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Association between Serum Vitamin D Levels and Risk of Sudden Sensorineural Hearing Loss: A cross-sectional Study. 血清维生素D水平与突发性感音神经性听力损失风险之间的关系:一项横断面研究。
Q3 Engineering
北京航空航天大学学报
Pub Date : 2023-12-01 Epub Date: 2023-06-02 DOI: 10.1007/s12070-023-03917-9
Afshin Zandi, Hassan Mehrad-Majd, Mohamad Reza Afzalzadeh

Background: Sudden sensorineural hearing loss (SSNHL) is an autoimmune diseases of the inner ear which is usually defined by acute onset of hearing loss in one or both ears, of 30 dB or more on at least three contiguous audiometric frequencies within 3 days or less. This study aimed to compare the serum levels of 25-hydroxyvitamin D (VitD) between patients with SSNHL and healthy controls.

Methods: A total of 50 patients with SSNHL and 50 healthy individuals without hearing loss as control group were enrolled in this study. Serum levels of VitD and other related laboratory tests such as calcium (Ca), phosphorus (P), and parathyroid hormone (PTH) were measured and compared between two study groups.

Results: Serum level of VitD was significantly lower in patients suffering from SSNHL compared to the healthy controls (26.55 ± 14.44 vs. 33.51 ± 14.21, P = 0.017, respectively). VitD insufficiency was observed in 70% (n = 35) of the patients with SSNHL as compared to 44% (n = 22) of healthy individuals, demonstrating a significant difference between two study groups. However, no statistically difference was observed for serum levels of Ca, P, and PTH.

Conclusion: This study indicated an increased prevalence of VitD insufficiency in subjects with SSNHL, suggesting a possible association between serum VitD levels and the development of SSNHL. VitD may protect the hearing loss through its antioxidant role.

背景:突发性感音神经性听力损失(SSNHL)是一种内耳自身免疫性疾病，通常定义为单耳或双耳急性听力损失，3天或更短时间内至少三个连续听力学频率的听力损失为30db或以上。本研究旨在比较SSNHL患者和健康对照者血清25-羟基维生素D (VitD)水平。方法:选取50例SSNHL患者和50例无听力损失的健康人作为对照组。测量并比较两个研究组之间的血清VitD水平和其他相关实验室测试，如钙(Ca)、磷(P)和甲状旁腺激素(PTH)。结果:SSNHL患者血清VitD水平显著低于健康对照组(26.55±14.44∶33.51±14.21,P = 0.017)。70% (n = 35)的SSNHL患者存在VitD功能不全，而44% (n = 22)的健康人存在VitD功能不全，两组之间存在显著差异。然而，血清钙、磷和甲状旁腺素水平无统计学差异。结论:本研究表明，SSNHL患者中维生素d不足的患病率增加，提示血清维生素d水平与SSNHL的发展可能存在关联。维生素d可能通过其抗氧化作用来保护听力损失。
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引用次数: 0
Novel damping-variable sliding mode cascade control for electro-hydrostatic actuator 一种新型变阻尼滑模串级控制的电静液执行器
Q3 Engineering
北京航空航天大学学报
Pub Date : 2021-09-06 DOI: 10.13700/J.BH.1001-5965.2020.0252
Wang Mingkang, Fu Yongling, Zhao Jiang'ao, Yang Rongrong
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引用次数: 0
Transpiration cooling test of porous plate in vacuum environment 多孔板在真空环境下的蒸腾冷却试验
Q3 Engineering
北京航空航天大学学报
Pub Date : 2021-09-06 DOI: 10.13700/J.BH.1001-5965.2020.0257
Chen Xingyu, Wang Liyan, C. Weihua, Wang Zhenfeng, Cao Zhanwei, Gao Yang
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引用次数: 0
Estimating number of birds around airport based on avian radar 基于鸟类雷达的机场周边鸟类数量估算
Q3 Engineering
北京航空航天大学学报
Pub Date : 2021-09-06 DOI: 10.13700/J.BH.1001-5965.2020.0278
C. Weishi, Huang Yifeng, LU Xianfeng, Zhang Jie, Chen Xiaolong
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引用次数: 2
Ship detector in SAR images based on EfficientDet without pre-training 基于EfficientDet的SAR图像船舶检测器
Q3 Engineering
北京航空航天大学学报
Pub Date : 2021-09-06 DOI: 10.13700/J.BH.1001-5965.2020.0255
Bao Zhuangzhuang, Zhao Xuejun
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引用次数: 1
Performance of oxygen-consuming catalytic inerting system of fuel tank under flight envelope 飞行包线下燃料箱耗氧催化惰化系统性能研究
Q3 Engineering
北京航空航天大学学报
Pub Date : 2021-09-06 DOI: 10.13700/J.BH.1001-5965.2020.0283
Peng Xiaotian, Feng Shiyu, Ren Tong, Z. Ruihua, Pan Jun, Wang Yangyang
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引用次数: 0
Dynamic modeling and simulation of irregular bearing failure 不规则轴承失效的动态建模与仿真
Q3 Engineering
北京航空航天大学学报
Pub Date : 2021-09-06 DOI: 10.13700/J.BH.1001-5965.2020.0232
Wang Zhen, Y. Zhengwei, HE Haohao, Ming Anbo, Zhang Wei
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引用次数: 3
Structural reliability calculation method based on improved weighted response surface 基于改进加权响应面的结构可靠度计算方法
Q3 Engineering
北京航空航天大学学报
Pub Date : 2021-09-06 DOI: 10.13700/J.BH.1001-5965.2020.0251
Wu Jie, Zhang Jianguo, You Lingfei, YE Nan
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引用次数: 0
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Q3 Engineering
北京航空航天大学学报
Pub Date : 2021-09-06 DOI: 10.13700/J.BH.1001-5965.2020.0250
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引用次数: 0
Buoyancy lifting scheme for marine risers in deep-sea mining system 深海采矿系统海洋立管浮力提升方案
Q3 Engineering
北京航空航天大学学报
Pub Date : 2021-09-06 DOI: 10.13700/J.BH.1001-5965.2020.0240
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引用次数: 0
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