Pub Date : 2024-05-10DOI: 10.59518/farabimedj.1449180
Z. Kırbaş, Elif Odabaşı Aktaş
Objective: This study aimed to examine the feeling of guilt experienced by mothers whose children are hospitalized and the factors affecting it. Methods: Data were collected from mothers whose children were hospitalized using a Personal Information Form and the Feeling of Guilt Scale for Mothers whose Children were Hospitalized. Analyzes were made in the SPSS 26 package program. P
{"title":"An Ignored Fact: Feeling of Guilt in Mothers Whose Children are Hospitalized","authors":"Z. Kırbaş, Elif Odabaşı Aktaş","doi":"10.59518/farabimedj.1449180","DOIUrl":"https://doi.org/10.59518/farabimedj.1449180","url":null,"abstract":"Objective: This study aimed to examine the feeling of guilt experienced by mothers whose children are hospitalized and the factors affecting it. \u0000Methods: Data were collected from mothers whose children were hospitalized using a Personal Information Form and the Feeling of Guilt Scale for Mothers whose Children were Hospitalized. Analyzes were made in the SPSS 26 package program. P","PeriodicalId":399200,"journal":{"name":"Farabi Tıp Dergisi","volume":" 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140990147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-12DOI: 10.59518/farabimedj.1415269
Akif Ci̇nel, Hüseyin Ipek, Altuğ Uşun, Kutay Çava, M. Aslan
Retractor systems are crucial in assisting physicians during surgical operations, ensuring optimal access to the surgical site, holding necessary equipment, and facilitating various procedures such as holding open wounds, stretching tissues, and removing them from the surgery site. Currently, retractors are tailored to specific anatomical regions. For instance, thyroid surgery presents unique challenges due to the gland's location and proximity to vital structures. Accessing the thyroid tissue amid the complexities of the neck region, which includes muscles like sternohyoid, sternothyroid, thyrohyoid, and omohyoid, requires careful retraction for a safe and effective procedure. The success of thyroid surgery relies on distinguishing the thyroid gland from surrounding structures, precisely determining surgical margins, and ensuring a clear view of the surgical field to mitigate potential complications. In this study, two distinct retractor holder designs, versatile for various operations, were developed and evaluated for their working volume, degrees of freedom in design, and applicability in surgical procedures. These designs aim to contribute to improving surgical outcomes, reducing complications, and general advances in the field of surgical instrumentation.
{"title":"Cerrahi Operasyonlarda Kullanılan Ekartörlerin Çalışma Hacmi ve Uygulamalarının Geliştirilmesi","authors":"Akif Ci̇nel, Hüseyin Ipek, Altuğ Uşun, Kutay Çava, M. Aslan","doi":"10.59518/farabimedj.1415269","DOIUrl":"https://doi.org/10.59518/farabimedj.1415269","url":null,"abstract":"Retractor systems are crucial in assisting physicians during surgical operations, ensuring optimal access to the surgical site, holding necessary equipment, and facilitating various procedures such as holding open wounds, stretching tissues, and removing them from the surgery site. Currently, retractors are tailored to specific anatomical regions. For instance, thyroid surgery presents unique challenges due to the gland's location and proximity to vital structures. Accessing the thyroid tissue amid the complexities of the neck region, which includes muscles like sternohyoid, sternothyroid, thyrohyoid, and omohyoid, requires careful retraction for a safe and effective procedure. The success of thyroid surgery relies on distinguishing the thyroid gland from surrounding structures, precisely determining surgical margins, and ensuring a clear view of the surgical field to mitigate potential complications. In this study, two distinct retractor holder designs, versatile for various operations, were developed and evaluated for their working volume, degrees of freedom in design, and applicability in surgical procedures. These designs aim to contribute to improving surgical outcomes, reducing complications, and general advances in the field of surgical instrumentation.","PeriodicalId":399200,"journal":{"name":"Farabi Tıp Dergisi","volume":"17 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140458213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-05DOI: 10.59518/farabimedj.1352413
Ali Beyazgül, Cahit Özer
Amaç: Araştırmada bir tıp fakültesinde eğitim alan öğrencilerin sağlıklı hayat tarzı davranışları ve esenlik halinin incelenmesi amaçlandı. Yöntemler: Kesitsel ve tanımlayıcı tipte tasarlanan çalışmanın evrenini bir tıp fakültesinde 2022-2023 eğitim yılında öğrenim gören tüm öğrenciler (n=1407 kişi) oluşturdu. Öğrencilerin % 23,52’sine ulaşıldı (n=331). "Sağlıklı Yaşam Biçimi Davranışları Ölçeği-II" (SYBDÖ-II) ve "Yeni Esenlik Ölçeği " kullanıldı. Verilerin analizinde Mann-Whitney U, Kruskal Wallis ve Spearman Korelasyon Testleri kullanıldı. Anlamlılık sınırı 0,05 olarak kabul edildi. Bulgular: Öğrencilerin SYBDÖ-II genel ortalaması 123,35±19,63 puandı. Kronik hastalığı olan 30 öğrencinin SYBDÖ-II puanı 114,66±17,13 iken kronik hastalığı olmayan 301 öğrencinin SYBDÖ-II puanı 124,22±19,68 idi (p=0,009). SYBDÖ-II’nin alt ölçeği olan Fiziksel Aktivite alt ölçeğinde en yüksek puan ortalaması dönem 3 (18,96±5,69), en düşük puan ortalaması dönem 5 öğrencilerine (16,04±5,32) aitti (p=0,006). SYBDÖ-II alt ölçeği olan Manevi Gelişim alt ölçeğinde dönem 1 puan ortalaması 26,22±4,63, dönem 6 puan ortalaması 22,78±5,37 idi (p=0,000). Öğrencilerin Yeni Esenlik Ölçeği genel ortalaması 80,38±16,11 puan idi. Yeni Esenlik Ölçeğinin alt ölçeği olan Kişilik ve Erdem alt ölçeğinde en yüksek puan ortalaması dönem 1 öğrencilerinde (16,57±2,74) iken en düşük puan ortalaması dönem 6 öğrencilerine (14,14±3,33) ait idi (p=0,000). SYBDÖ-II ile Yeni Esenlik Ölçeği karşılaştırıldığında pozitif yönde orta derecede korelasyon mevcuttu (p=0,000, r = 0,574). Sonuç: Ölçekler arasında orta derecede korelasyon görüldü. Sağlıklı yaşam tarzları ve uygulanması konusu, tıp fakültesi öğrencilerinin meslek hayatlarında örnek olmaları açısından eğitim müfredatına eklenebilir.
{"title":"Investigation of Healthy Lifestyle Behaviors and Well-Being in Medical Students","authors":"Ali Beyazgül, Cahit Özer","doi":"10.59518/farabimedj.1352413","DOIUrl":"https://doi.org/10.59518/farabimedj.1352413","url":null,"abstract":"Amaç: Araştırmada bir tıp fakültesinde eğitim alan öğrencilerin sağlıklı hayat tarzı davranışları ve esenlik halinin incelenmesi amaçlandı. \u0000Yöntemler: Kesitsel ve tanımlayıcı tipte tasarlanan çalışmanın evrenini bir tıp fakültesinde 2022-2023 eğitim yılında öğrenim gören tüm öğrenciler (n=1407 kişi) oluşturdu. Öğrencilerin % 23,52’sine ulaşıldı (n=331). \"Sağlıklı Yaşam Biçimi Davranışları Ölçeği-II\" (SYBDÖ-II) ve \"Yeni Esenlik Ölçeği \" kullanıldı. Verilerin analizinde Mann-Whitney U, Kruskal Wallis ve Spearman Korelasyon Testleri kullanıldı. Anlamlılık sınırı 0,05 olarak kabul edildi. \u0000Bulgular: Öğrencilerin SYBDÖ-II genel ortalaması 123,35±19,63 puandı. Kronik hastalığı olan 30 öğrencinin SYBDÖ-II puanı 114,66±17,13 iken kronik hastalığı olmayan 301 öğrencinin SYBDÖ-II puanı 124,22±19,68 idi (p=0,009). SYBDÖ-II’nin alt ölçeği olan Fiziksel Aktivite alt ölçeğinde en yüksek puan ortalaması dönem 3 (18,96±5,69), en düşük puan ortalaması dönem 5 öğrencilerine (16,04±5,32) aitti (p=0,006). SYBDÖ-II alt ölçeği olan Manevi Gelişim alt ölçeğinde dönem 1 puan ortalaması 26,22±4,63, dönem 6 puan ortalaması 22,78±5,37 idi (p=0,000). Öğrencilerin Yeni Esenlik Ölçeği genel ortalaması 80,38±16,11 puan idi. Yeni Esenlik Ölçeğinin alt ölçeği olan Kişilik ve Erdem alt ölçeğinde en yüksek puan ortalaması dönem 1 öğrencilerinde (16,57±2,74) iken en düşük puan ortalaması dönem 6 öğrencilerine (14,14±3,33) ait idi (p=0,000). SYBDÖ-II ile Yeni Esenlik Ölçeği karşılaştırıldığında pozitif yönde orta derecede korelasyon mevcuttu (p=0,000, r = 0,574). \u0000Sonuç: Ölçekler arasında orta derecede korelasyon görüldü. Sağlıklı yaşam tarzları ve uygulanması konusu, tıp fakültesi öğrencilerinin meslek hayatlarında örnek olmaları açısından eğitim müfredatına eklenebilir.","PeriodicalId":399200,"journal":{"name":"Farabi Tıp Dergisi","volume":"142 45","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138598827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-24DOI: 10.59518/farabimedj.1354783
Serdar Özdemir, İbrahim Altunok, A. Algın
Introduction: One of the most common post-traumatic injuries and pain areas in the community is the distal lower extremity. In this study, we aimed to evaluate the demographic data and injured tissue of the patients who applied to the emergency department with foot and ankle injuries and to reveal the relationship between them. Materials and Methods: This study was conducted by retrospectively evaluating the data of the patients who applied to the emergency department of a tertiary hospital during the two-month period between 01.01.2019 and 28.02.2019. Files of patients with foot and ankle injuries were reviewed retrospectively using the hospital computer-based data system. In order to determine foot and ankle injuries, patients who had short leg splints were identified and included in the study using the hospital computer-based data system. The fractured bones were grouped as tibia, fibula, talus, calcaneus, cuboid bone, navicular bone, cuneiform bone and 1st, 2nd, 3rd, 4th, 5th metatarsal bones and proximal phalanx. Trauma mechanisms were grouped as falling from height, falling from the same level, beating, sports injury, traffic accident and sprain. Results: Of the 133 patients included in the study, 68 (51.1%) were female. The age ranged between 1 and 78 years, with a median of 28. The most common bone fracture was the fibula (42.9%). As the cases were evaluated according to the trauma mechanisms, falling from a height 5 (3.8%), falling on the same level 79 (59.4%), beating 4 (3%), sports injury 3 (2.3%), traffic accident 2 (1.5%) and sprain was 40 (30.1%). As the injuries are evaluated; there was one bone fracture in 118 (88.7%) cases, and more than three bone fractures in 15 (11.3%) cases. As the relationship between fractured bone and age was evaluated, it was observed that there was a statistically significant relationship between the calcaneus, first metatarsal and fifth metatarsal (Mann-Whitney U test, for calcaneus p: 0.003, for 1st metatarsal bone p
{"title":"Evaluation of Foot and Ankle Trauma Registering to Emergency Department","authors":"Serdar Özdemir, İbrahim Altunok, A. Algın","doi":"10.59518/farabimedj.1354783","DOIUrl":"https://doi.org/10.59518/farabimedj.1354783","url":null,"abstract":"Introduction: One of the most common post-traumatic injuries and pain areas in the community is the distal lower extremity. In this study, we aimed to evaluate the demographic data and injured tissue of the patients who applied to the emergency department with foot and ankle injuries and to reveal the relationship between them. Materials and Methods: This study was conducted by retrospectively evaluating the data of the patients who applied to the emergency department of a tertiary hospital during the two-month period between 01.01.2019 and 28.02.2019. Files of patients with foot and ankle injuries were reviewed retrospectively using the hospital computer-based data system. In order to determine foot and ankle injuries, patients who had short leg splints were identified and included in the study using the hospital computer-based data system. The fractured bones were grouped as tibia, fibula, talus, calcaneus, cuboid bone, navicular bone, cuneiform bone and 1st, 2nd, 3rd, 4th, 5th metatarsal bones and proximal phalanx. Trauma mechanisms were grouped as falling from height, falling from the same level, beating, sports injury, traffic accident and sprain. Results: Of the 133 patients included in the study, 68 (51.1%) were female. The age ranged between 1 and 78 years, with a median of 28. The most common bone fracture was the fibula (42.9%). As the cases were evaluated according to the trauma mechanisms, falling from a height 5 (3.8%), falling on the same level 79 (59.4%), beating 4 (3%), sports injury 3 (2.3%), traffic accident 2 (1.5%) and sprain was 40 (30.1%). As the injuries are evaluated; there was one bone fracture in 118 (88.7%) cases, and more than three bone fractures in 15 (11.3%) cases. As the relationship between fractured bone and age was evaluated, it was observed that there was a statistically significant relationship between the calcaneus, first metatarsal and fifth metatarsal (Mann-Whitney U test, for calcaneus p: 0.003, for 1st metatarsal bone p","PeriodicalId":399200,"journal":{"name":"Farabi Tıp Dergisi","volume":"365 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139240639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-20DOI: 10.59518/farabimedj.1382097
F. Öznurhan, Aylin Özel
ÖZET Amaç:Bu çalışmanın amacı, akıllı kromatik teknoloji özelliğine sahip rezin esaslı restoratif materyallerin farklı pH değerlerindeki sıvılarda bekletilmesinin, yüzey pürüzlülüğüne ve renk değişimlerine etkilerini karşılaştırmalı olarak incelemektir. Gereç ve Yöntemler:Bu çalışmada üç rezin restoratif materyal;Omnichroma, VittraAPS Unique,Charisma DiamondONE ve iki farklı polisaj sistemi; Clearfil Twist Dia,Super-Snap kullanılmıştır.Her bir grup için 80adet olmak üzere toplamda 240örnek hazırlanmış ve yapay tükürük kontrol grubu olmak üzere kola, portakallı gazoz ve aromalı soğuk çay olmak üzere 4farklı sıvıda bekletilerek, başlangıç,7.gün ve14.günün sonundaki renk stabilitesi ve yüzey pürüzlülüğü değerlerindeki değişiklikler incelenmiştir.Örneklerin renk değişimleri spektrofotometre ile yüzey pürüzlülükleri ise profilometre ile ölçülmüştür.Klinik tip spektrofotometre cihazı ile renklendirme öncesi/sonrası renkler ölçülmüş ve ∆E* değerleri hesaplanmıştır.Veriler istatistiksel olarak değerlendirilmiştir. Bulgular:Kompozit grupları arasında 14günlük deney periyodu sonrası pürüzlülük değerleri(Ra) incelendiğinde, en az yüzey pürüzlülüğü Charisma DiamondONE kompozit rezinde görülürken, en fazla yüzey pürüzlülüğü Omnichroma’da gözlenmiştir. Gruplar ikişerli karşılaştırıldığında istatistiksel olarak anlamlı bir fark bulunamamıştır(p>0,05). Kompozit grupları arasındaki başlangıç ve 14.gün renk değişim değerleri(ΔE2) incelendiğinde; Super-Snap alt grubunda, sıvılardan en fazla etkilenen kompozit rezin Vittra APS Unique iken Clearfil Twist Dia alt grubunda sıvılardan en fazla Omnichroma olmuştur. En fazla etkileyen sıvı ise aromalı soğuk çay(6,39 ± 9,29) olarak bulunmuştur. Sıvılar arasındaki fark istatistiksel olarak anlamlı bulunmamıştır (p>0,05). Sonuç:Yapılan bu çalışmanın sonuçları incelendiğinde renk stabilitesi ve pürüzlülük bakımından eroziv potansiyele sahip asidik sıvıların kullanılan restoratif materyallerin yüzey özelliklerini farklı oranlarda etkilediği,Super-Snap bitirme ve cila sisteminin in vitro koşullarda kullanılan yüzeylere daha uyumlu olduğu, in vivo koşulların in vitro koşullardan farklılık gösterebileceği, dolayısıyla ağız içerisindeki kompozitlerin renklerini zaman içerisinde etkileyebileceği görülmüştür.
{"title":"EVALUATION OF SURFACE ROUGHNESS AND COLOR CHANGES AFTER HOLDING COMPOSITE RESINS WITH SMART CHROMATIC TECHNOLOGY IN LIQUIDS WITH DIFFERENT PH VALUES","authors":"F. Öznurhan, Aylin Özel","doi":"10.59518/farabimedj.1382097","DOIUrl":"https://doi.org/10.59518/farabimedj.1382097","url":null,"abstract":"ÖZET Amaç:Bu çalışmanın amacı, akıllı kromatik teknoloji özelliğine sahip rezin esaslı restoratif materyallerin farklı pH değerlerindeki sıvılarda bekletilmesinin, yüzey pürüzlülüğüne ve renk değişimlerine etkilerini karşılaştırmalı olarak incelemektir. Gereç ve Yöntemler:Bu çalışmada üç rezin restoratif materyal;Omnichroma, VittraAPS Unique,Charisma DiamondONE ve iki farklı polisaj sistemi; Clearfil Twist Dia,Super-Snap kullanılmıştır.Her bir grup için 80adet olmak üzere toplamda 240örnek hazırlanmış ve yapay tükürük kontrol grubu olmak üzere kola, portakallı gazoz ve aromalı soğuk çay olmak üzere 4farklı sıvıda bekletilerek, başlangıç,7.gün ve14.günün sonundaki renk stabilitesi ve yüzey pürüzlülüğü değerlerindeki değişiklikler incelenmiştir.Örneklerin renk değişimleri spektrofotometre ile yüzey pürüzlülükleri ise profilometre ile ölçülmüştür.Klinik tip spektrofotometre cihazı ile renklendirme öncesi/sonrası renkler ölçülmüş ve ∆E* değerleri hesaplanmıştır.Veriler istatistiksel olarak değerlendirilmiştir. Bulgular:Kompozit grupları arasında 14günlük deney periyodu sonrası pürüzlülük değerleri(Ra) incelendiğinde, en az yüzey pürüzlülüğü Charisma DiamondONE kompozit rezinde görülürken, en fazla yüzey pürüzlülüğü Omnichroma’da gözlenmiştir. Gruplar ikişerli karşılaştırıldığında istatistiksel olarak anlamlı bir fark bulunamamıştır(p>0,05). Kompozit grupları arasındaki başlangıç ve 14.gün renk değişim değerleri(ΔE2) incelendiğinde; Super-Snap alt grubunda, sıvılardan en fazla etkilenen kompozit rezin Vittra APS Unique iken Clearfil Twist Dia alt grubunda sıvılardan en fazla Omnichroma olmuştur. En fazla etkileyen sıvı ise aromalı soğuk çay(6,39 ± 9,29) olarak bulunmuştur. Sıvılar arasındaki fark istatistiksel olarak anlamlı bulunmamıştır (p>0,05). Sonuç:Yapılan bu çalışmanın sonuçları incelendiğinde renk stabilitesi ve pürüzlülük bakımından eroziv potansiyele sahip asidik sıvıların kullanılan restoratif materyallerin yüzey özelliklerini farklı oranlarda etkilediği,Super-Snap bitirme ve cila sisteminin in vitro koşullarda kullanılan yüzeylere daha uyumlu olduğu, in vivo koşulların in vitro koşullardan farklılık gösterebileceği, dolayısıyla ağız içerisindeki kompozitlerin renklerini zaman içerisinde etkileyebileceği görülmüştür.","PeriodicalId":399200,"journal":{"name":"Farabi Tıp Dergisi","volume":"68 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139258973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In the study, the factors that can be effective in choosing oral and dental health care products for their children were evaluated. A descriptive survey was applied to the parents (n=270) of children aged 0-14. Descriptive statistics and chi-square tests were used in the analysis. A p
{"title":"Evaluation Of Parents' Selection Criteria and Related Factors of Oral and Dental Health Care Products Used by Their Children","authors":"Hilal ŞENOCAK, Tamer TÜZÜNER, Gülin RENDA, Büşra KORKMAZ, Özlem ÇOBAN","doi":"10.59518/farabimedj.1356871","DOIUrl":"https://doi.org/10.59518/farabimedj.1356871","url":null,"abstract":"In the study, the factors that can be effective in choosing oral and dental health care products for their children were evaluated. A descriptive survey was applied to the parents (n=270) of children aged 0-14. Descriptive statistics and chi-square tests were used in the analysis. A p","PeriodicalId":399200,"journal":{"name":"Farabi Tıp Dergisi","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135970143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-26DOI: 10.59518/farabimedj.1328565
Öznur DEMİRTAŞ, Ayşegül SÜMER
ABSTRACT
Objective: The aim is to explain the role of the gastrointestinal system in obesity and related complications by focusing on the biological mechanisms between obesity and the gastrointestinal system, based on the latest evidence in the literature.
Methods: A systematic search of the literature in the PubMed and ScienceDirect databases was conducted.
Results: Factors such as inflammation, mechanical space-occupying effect, microbiota, adipocyte peptides are involved in the development of obesity-related gastrointestinal system comorbidities. However, obesity occurs when the connection between the gastrointestinal tract and the brain changes. Signaling dysfunction disrupts the brain-gut axis, leading to increased frequency of food intake and excessive fat accumulation.
Conclusion: Obesity increases the risk of developing gastrointestinal system disorders. However, the gastrointestinal tract and its pathophysiology play a key role in the regulation of food intake and subsequent progression to obesity.
{"title":"Obesity And Gastrointestinal Regulation Of Food Intake","authors":"Öznur DEMİRTAŞ, Ayşegül SÜMER","doi":"10.59518/farabimedj.1328565","DOIUrl":"https://doi.org/10.59518/farabimedj.1328565","url":null,"abstract":"ABSTRACT
 
 Objective: The aim is to explain the role of the gastrointestinal system in obesity and related complications by focusing on the biological mechanisms between obesity and the gastrointestinal system, based on the latest evidence in the literature.
 Methods: A systematic search of the literature in the PubMed and ScienceDirect databases was conducted.
 Results: Factors such as inflammation, mechanical space-occupying effect, microbiota, adipocyte peptides are involved in the development of obesity-related gastrointestinal system comorbidities. However, obesity occurs when the connection between the gastrointestinal tract and the brain changes. Signaling dysfunction disrupts the brain-gut axis, leading to increased frequency of food intake and excessive fat accumulation.
 Conclusion: Obesity increases the risk of developing gastrointestinal system disorders. However, the gastrointestinal tract and its pathophysiology play a key role in the regulation of food intake and subsequent progression to obesity.","PeriodicalId":399200,"journal":{"name":"Farabi Tıp Dergisi","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134886315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-19DOI: 10.59518/farabimedj.1325315
Nergiz ERKUT
ÖZET
Hodgkin lenfoma (HL), lenfatik sistemin nadir görülen malign bir neoplazisidir. Tüm lenfomaların yaklaşık %10’unu oluşturmaktadır. Sıklıkla gençlerde izlenmekle birlikte, daha az oranda yaşlılarda da gözlenmektedir. HL, germinal merkez B lenfositlerden kaynaklanan ve tümöral mikroçevrede belirgin inflamatuvar hücre artışı ile karakterize bir malignensidir. Klinik ve patolojik özellikleri farklı olan klasik HL ve nodüler lenfosit-predominant HL (NLPHL) olmak üzere iki tipi mevcuttur. Klasik HL vakaların %90-%95’ini, NLPHL ise %5-10’unu oluşturmaktadır. Kemoterapi ve/veya radyoterapi ile hastaların yaklaşık %80’inde kür sağlanmaktadır. Bu derlemede HL’nin epidemiyoloji, etiyoloji, patobiyoloji, klinik, tanı ve tedavisi üzerinde durulacaktır.
摘要；霍奇金淋巴瘤（HL）是一种罕见的淋巴系统恶性肿瘤。它约占所有淋巴瘤的 10%。虽然它最常见于年轻人，但在老年人中的发病率也较低。HL 是一种由生殖中心 B 淋巴细胞引起的恶性肿瘤，其特点是肿瘤微环境中炎症细胞明显增多。HL分为两种类型，即典型HL和结节性淋巴细胞为主的HL（NLPHL），它们具有不同的临床和病理特征。传统型HL占90%-95%，NLPHL占5%-10%。约80%的患者可通过化疗和/或放疗治愈。本综述将重点介绍HL的流行病学、病因学、病理生物学、临床、诊断和治疗。
{"title":"Hodgkin Lymphoma","authors":"Nergiz ERKUT","doi":"10.59518/farabimedj.1325315","DOIUrl":"https://doi.org/10.59518/farabimedj.1325315","url":null,"abstract":"ÖZET
 Hodgkin lenfoma (HL), lenfatik sistemin nadir görülen malign bir neoplazisidir. Tüm lenfomaların yaklaşık %10’unu oluşturmaktadır. Sıklıkla gençlerde izlenmekle birlikte, daha az oranda yaşlılarda da gözlenmektedir. HL, germinal merkez B lenfositlerden kaynaklanan ve tümöral mikroçevrede belirgin inflamatuvar hücre artışı ile karakterize bir malignensidir. Klinik ve patolojik özellikleri farklı olan klasik HL ve nodüler lenfosit-predominant HL (NLPHL) olmak üzere iki tipi mevcuttur. Klasik HL vakaların %90-%95’ini, NLPHL ise %5-10’unu oluşturmaktadır. Kemoterapi ve/veya radyoterapi ile hastaların yaklaşık %80’inde kür sağlanmaktadır. Bu derlemede HL’nin epidemiyoloji, etiyoloji, patobiyoloji, klinik, tanı ve tedavisi üzerinde durulacaktır.","PeriodicalId":399200,"journal":{"name":"Farabi Tıp Dergisi","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135061291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-28DOI: 10.59518/farabimedj.1323840
Mustafa Kandaz, Atalay Balsak, Kaan Aydoğdu, H. Çobanoğlu
Objective: It was aimed to evaluate the acute side effects of patients treated in our clinic with nasopharyngeal cancer who underwent definitive chemoradiotherapy. Materials and Methods: 64 patients diagnosed with nasopharyngeal cancer and treated between January 2010 and May 2023 were included in the study. Definitive chemoradiotherapy with intensity modulated radiotherapy was applied to the patients. While 70 Gy of radiotherapy was given to tumor and positive lymph nodes, 60 Gy of radiotherapy was applied to all nasopharynx and bilateral neck lymph nodes. The three rounds of cisplatin 100 mg/m2 (days 1, 22 and 43) or 40 mg/m2 weekly of chemotherapy were used for treatment. The acute side effects of the patients were noted and evaluated. Results: The mean age of the patients was 51.05±14.46 (range: 20-82) years. Of the patients included in the study, 15 (23%) were stage II, 37 (58%) were stage III, and 12 (19%) were stage IV. 41 (64%) patients were male and 23 (36%) were female. In male, the rates of grade 2 and 3 hematological toxicity were 47% and 20%, respectively. In female, the rates of grade 2 and 3 hematological toxicity were 53% and 80%, respectively. There was a significant difference in the rate of hematological toxicity between the 2 groups (z=16.882, p= 0.0001). The rates of grade 2 and 3 hematological toxicity in patients younger than 65 years were 47% and 20%, respectively. In patients older than 65 years, the rates of grade 2 and 3 esophagitis were 53% and 80%, respectively. There was a significant difference in esophagitis rate between the 2 groups (z =18.360, p= 0.0001). Conclusion: Despite the technological treatment devices and methods, the risk of acute toxicity is high in the treatment of nasopharyngeal cancer due to its anatomical location. Our study was found to be compatible with the literature in terms of acute side effects. Strict follow-up and treatment of acute side effects may increase the patient's adherence to treatment, improve quality of life, and increase the effectiveness of treatment.
{"title":"Nazofarengeal Karsinom Tedavisinde Yoğunluk Ayarlı Radyoterapi ile Kombine Kemoterapinin Akut Yan Etkileri","authors":"Mustafa Kandaz, Atalay Balsak, Kaan Aydoğdu, H. Çobanoğlu","doi":"10.59518/farabimedj.1323840","DOIUrl":"https://doi.org/10.59518/farabimedj.1323840","url":null,"abstract":"Objective: It was aimed to evaluate the acute side effects of patients treated in our clinic with nasopharyngeal cancer who underwent definitive chemoradiotherapy. \u0000Materials and Methods: 64 patients diagnosed with nasopharyngeal cancer and treated between January 2010 and May 2023 were included in the study. Definitive chemoradiotherapy with intensity modulated radiotherapy was applied to the patients. While 70 Gy of radiotherapy was given to tumor and positive lymph nodes, 60 Gy of radiotherapy was applied to all nasopharynx and bilateral neck lymph nodes. The three rounds of cisplatin 100 mg/m2 (days 1, 22 and 43) or 40 mg/m2 weekly of chemotherapy were used for treatment. The acute side effects of the patients were noted and evaluated. \u0000Results: The mean age of the patients was 51.05±14.46 (range: 20-82) years. Of the patients included in the study, 15 (23%) were stage II, 37 (58%) were stage III, and 12 (19%) were stage IV. 41 (64%) patients were male and 23 (36%) were female. In male, the rates of grade 2 and 3 hematological toxicity were 47% and 20%, respectively. In female, the rates of grade 2 and 3 hematological toxicity were 53% and 80%, respectively. There was a significant difference in the rate of hematological toxicity between the 2 groups (z=16.882, p= 0.0001). The rates of grade 2 and 3 hematological toxicity in patients younger than 65 years were 47% and 20%, respectively. In patients older than 65 years, the rates of grade 2 and 3 esophagitis were 53% and 80%, respectively. There was a significant difference in esophagitis rate between the 2 groups (z =18.360, p= 0.0001). \u0000Conclusion: Despite the technological treatment devices and methods, the risk of acute toxicity is high in the treatment of nasopharyngeal cancer due to its anatomical location. Our study was found to be compatible with the literature in terms of acute side effects. Strict follow-up and treatment of acute side effects may increase the patient's adherence to treatment, improve quality of life, and increase the effectiveness of treatment.","PeriodicalId":399200,"journal":{"name":"Farabi Tıp Dergisi","volume":"331 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134330971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-27DOI: 10.59518/farabimedj.1347185
S. Özdemir, A. Algın
Akut SARS-CoV-2 enfeksiyonu ile ilişkili çoğu kardiyak komplikasyon, hastanın klinik seyrini zorlaştırır ve yüksek morbidite ve mortalite ile ilişkilidir. Enfeksiyondan sonra hayatta kalan hastalar, uzun süreli kardiyak komplikasyonlar açısından risk altındadır.
{"title":"Long-Term Cardiac Effects After Recovery in SARS-CoV-2 Infection","authors":"S. Özdemir, A. Algın","doi":"10.59518/farabimedj.1347185","DOIUrl":"https://doi.org/10.59518/farabimedj.1347185","url":null,"abstract":"Akut SARS-CoV-2 enfeksiyonu ile ilişkili çoğu kardiyak komplikasyon, hastanın klinik seyrini zorlaştırır ve yüksek morbidite ve mortalite ile ilişkilidir. Enfeksiyondan sonra hayatta kalan hastalar, uzun süreli kardiyak komplikasyonlar açısından risk altındadır.","PeriodicalId":399200,"journal":{"name":"Farabi Tıp Dergisi","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128842761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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