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Adolescent Medicine: State of the Art Reviews最新文献

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Addressing Firearm Violence in the Primary Health Care Setting. 解决初级卫生保健环境中的枪支暴力问题。
Eric Sigel
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引用次数: 0
Esophagitis in Adolescents. 青少年食管炎。
Pub Date : 2016-05-16 DOI: 10.1542/9781581109382-esophagitis
P. Putnam
Esophagitis is the end result of a variety of insults to epithelial homeostasis. Eosinophilic esophagitis is a manifestation of non-IgE-mediated food allergy that most commonly affects the esophagus of males who have other atopic phenomena. Reflux esophagitis reflects repeated exposure to acidic gastric contents because of failure of the normal protections afforded by the LES. Because certain histologic features can be present in either condition, endoscopic biopsy alone does not distinguish them. Their symptoms overlap, but the treatment options are very different, such that making a formal diagnosis by following consensus guidelines is essential. A treatment protocol designed to manage the inflammation by controlling the provocative factors (acid for GERD and food antigens for EoE) or suppressing the inflammation (ie, topical steroids for EoE) should result in normalization of the mucosa and resolution of symptoms. Eosinophilic esophagitis is a chronic condition that rarely remits spontaneously, so any therapeutic modality will need to be continued indefinitely.
食管炎是对上皮稳态的各种损害的最终结果。嗜酸性粒细胞性食管炎是一种非ige介导的食物过敏的表现,最常见于有其他特应性现象的男性食道。反流性食管炎反映了由于LES提供的正常保护失效而反复暴露于酸性胃内容物。因为某些组织学特征可以出现在这两种情况下,内镜活检本身并不能区分它们。他们的症状重叠,但治疗方案非常不同,因此根据共识指南做出正式诊断至关重要。通过控制刺激因素(胃酸治疗胃食管反流,食物抗原治疗EoE)或抑制炎症(即局部类固醇治疗EoE)来控制炎症的治疗方案应该导致粘膜正常化和症状缓解。嗜酸性粒细胞性食管炎是一种慢性疾病,很少自发缓解,因此任何治疗方式都需要无限期地持续下去。
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引用次数: 0
Gastrointestinal Issues in Adolescents with Eating Disorders. 青少年饮食失调的胃肠问题。
Pub Date : 2016-05-16 DOI: 10.1542/9781581109382-gastrointestinal_issues
M. E. Pérez, C. Kapphahn
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引用次数: 0
Vitamin D in Health and Disease in Adolescents: When to Screen, Whom to Treat, and How to Treat. 青少年健康和疾病中的维生素D:何时筛查,治疗谁,以及如何治疗。
Pub Date : 2016-05-16 DOI: 10.1542/9781581109382-vitamin
N. Golden, D. Carey
The existing guidelines on screening and treatment are confusing because different guidelines target different populations. The IOM and AAP guidelines target generally healthy populations, whereas the Endocrine Society and other subspecialty guidelines target individuals with specific medical conditions associated with increased bone fragility. These distinctions have not always been well articulated. For healthy adolescents, the AAP does not recommend universal screening or screening of obese or dark-skinned individuals. Increased dietary intake of vitamin D is recommended, and vitamin D supplementation can be considered if the RDA cannot be met. For adolescents with chronic medical illnesses associated with increased fracture risk, screening for vitamin D deficiency should be performed by obtaining a serum 25-OHD level. Those found to be deficient (25-OHD level < 20 ng/mL) should be treated with doses of vitamin D2 or vitamin D3 higher than the daily requirement (as discussed in the section on vitamin D and chronic disease), followed by a maintenance dose. A repeat 25-OHD level should be obtained after the therapeutic course is completed. Some experts advocate for achievement of 25-OHD levels greater than 30 ng/mL in conditions associated with increased bone fragility, and several pediatric subspecialty organizations have made recommendations specific to the diseases they treat. In such instances, the recommendations of the pediatric subspecialty organizations should take precedence over the AAP recommendations for adolescents with chronic illnesses associated with increased bone fragility because the AAP recommendations were primarily targeted at a healthy population.
现有的筛查和治疗指南令人困惑,因为不同的指南针对不同的人群。美国医学学会和美国儿科学会的指南针对的是一般健康人群,而内分泌学会和其他亚专科指南针对的是患有与骨质脆性增加相关的特定疾病的个体。这些区别并不总是很清楚。对于健康的青少年,美国儿科学会不建议进行普遍筛查,也不建议对肥胖或深色皮肤的人进行筛查。建议增加饮食中维生素D的摄入量,如果不能达到RDA,可以考虑补充维生素D。对于患有与骨折风险增加相关的慢性医学疾病的青少年,应通过获得血清25-OHD水平来筛查维生素D缺乏症。那些发现缺乏维生素D (25-OHD水平< 20 ng/mL)的人应该服用高于每日所需剂量的维生素D2或维生素D3(如维生素D和慢性疾病一节所述),然后服用维持剂量。治疗疗程结束后应再次检测25-OHD水平。一些专家主张,在与骨质脆性增加相关的情况下,25-OHD水平应大于30 ng/mL,一些儿科亚专科组织已针对他们治疗的疾病提出了具体建议。在这种情况下,儿科亚专科组织的建议应优先于美国儿科学会的建议,因为美国儿科学会的建议主要针对健康人群,适用于患有与骨质脆性增加相关的慢性疾病的青少年。
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引用次数: 15
Health Care Maintenance in Adolescents with Inflammatory Bowel Disease. 青少年炎症性肠病的保健维护。
Pub Date : 2016-05-16 DOI: 10.1542/9781581109382-health_care
P. Rufo, Matthew D. Egberg
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引用次数: 0
Contemporary Dietary Practices: FODMAPs and Beyond. 当代饮食实践:FODMAPs及其他。
Pub Date : 2016-05-16 DOI: 10.1542/9781581109382-contemporary
S. Dharmapuri, Kyndal Hettich, P. Goday
There is no diet that is recommended for all individuals. Some special diets (eg, gluten-free for celiac disease) are necessary for health and quality of life. Other diets may be recommended for a short period of time to aid in symptom relief but may not be recommended for the long- term (eg, LFD). Popular diets continue to come and go with varying levels of success. When considering adolescents, continued growth and development are most important, and restrictive diets can lead to nutrient inadequacies and poor growth. Before making any recommendation, it is important to consider the goal of the diet and the cost versus benefits associated with following the diet. Adherence is always a challenge, regardless of the type of diet implemented. If a special diet is not warranted for the health, safety, and desired quality of life of the individual, it should not be implemented.
没有一种饮食是适合所有人的。一些特殊的饮食(如乳糜泻的无麸质饮食)对健康和生活质量是必要的。其他饮食可以在短时间内推荐,以帮助缓解症状,但可能不推荐长期(如LFD)。流行的饮食法来来去去,取得了不同程度的成功。考虑到青少年,持续生长发育是最重要的,限制性饮食可能导致营养不足和生长不良。在提出任何建议之前,重要的是要考虑饮食的目标以及遵循饮食的成本与收益。无论采用哪种饮食方式,坚持都是一个挑战。如果一种特殊饮食对个人的健康、安全和期望的生活质量没有保证,就不应该实施。
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引用次数: 2
Celiac Disease, Wheat Allergy, and Non-Celiac Gluten Sensitivity: What's the Difference? 乳糜泻,小麦过敏和非乳糜泻麸质敏感:有什么区别?
Pub Date : 2016-05-16 DOI: 10.1542/9781581109382-celiac
F. T. Mitsinikos, M. Pietzak
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引用次数: 0
Advances in Pain-Predominant Functional Gastrointestinal Disorders in the Adolescent. 青少年以疼痛为主的功能性胃肠疾病的研究进展。
Pub Date : 2016-05-16 DOI: 10.1542/9781581109382-advances
J. Rosen, Anthony Alioto, M. Saps
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引用次数: 0
Advances in Pediatric Inflammatory Bowel Disease. 儿童炎症性肠病研究进展
Pub Date : 2016-05-16 DOI: 10.1542/9781581109382-advances_in
Elizabeth C. Maxwell, A. Grossman
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引用次数: 1
The Gut Microbiome and Probiotics. 肠道微生物群和益生菌。
Pub Date : 2016-05-16 DOI: 10.1542/9781581109382-the_gut
Anam Fatima, F. Sylvester
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引用次数: 1
期刊
Adolescent Medicine: State of the Art Reviews
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