Pub Date : 2019-10-29DOI: 10.2174/1872211313666191029144038
Y. Dang, P. Tran, T. Tran
Background Natural materials have been encouraged in controlled drug release and improved drug bioavailability. Objective This study aimed to develop a modification process for the use of a natural material, Ocimum gratissimum seeds (OGS), in Orally Disintegrating Tablets (ODTs). Methods The OGS was investigated with four different modification processes including only milling, swelling, swelling/milling, and swelling/milling/incubation. The ODTs containing the modified OGS as a disintegrant were prepared by the wet granulation method. Furthermore, an evaluation to assess parameters of tablets, such as weight variation, hardness, friability, wetting time, disintegration time, drug content, and dissolution studies, was performed. Results The modification of OGS using the swelling/ milling process resulted in a completion of OGS modification, leading to an ideal wetting time, disintegrating time, and dissolution rate. The OGS concentrations also affected the wetting and disintegrating time with the optimal range of ODTs from 15% to 20%. On the other hand, the modification with the incubation processes varied by temperature and time increased the wetting time and disintegrating time. Conclusions The modified OGS demonstrated that it is a potential material with the advantages of cost-effectiveness, non-toxicity and easy manufacture in the preparation of ODTs.
{"title":"Development of the Modified Ocimum gratissimum Seeds for Orally Disintegrating Tablets","authors":"Y. Dang, P. Tran, T. Tran","doi":"10.2174/1872211313666191029144038","DOIUrl":"https://doi.org/10.2174/1872211313666191029144038","url":null,"abstract":"Background Natural materials have been encouraged in controlled drug release and improved drug bioavailability. Objective This study aimed to develop a modification process for the use of a natural material, Ocimum gratissimum seeds (OGS), in Orally Disintegrating Tablets (ODTs). Methods The OGS was investigated with four different modification processes including only milling, swelling, swelling/milling, and swelling/milling/incubation. The ODTs containing the modified OGS as a disintegrant were prepared by the wet granulation method. Furthermore, an evaluation to assess parameters of tablets, such as weight variation, hardness, friability, wetting time, disintegration time, drug content, and dissolution studies, was performed. Results The modification of OGS using the swelling/ milling process resulted in a completion of OGS modification, leading to an ideal wetting time, disintegrating time, and dissolution rate. The OGS concentrations also affected the wetting and disintegrating time with the optimal range of ODTs from 15% to 20%. On the other hand, the modification with the incubation processes varied by temperature and time increased the wetting time and disintegrating time. Conclusions The modified OGS demonstrated that it is a potential material with the advantages of cost-effectiveness, non-toxicity and easy manufacture in the preparation of ODTs.","PeriodicalId":40024,"journal":{"name":"Recent Patents on Drug Delivery and Formulation","volume":"14 1","pages":"40 - 47"},"PeriodicalIF":0.0,"publicationDate":"2019-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2174/1872211313666191029144038","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47329293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Que ce soit a la maison ou en salon de coiffure, de nombreuses personnes se colorent les cheveux. Une large gamme de produits, aux palettes de couleurs tres variees et a l’utilisation aisee, est proposee aux consommateurs. Ils ont le choix entre des colorations capillaires permanentes, semi-permanentes ou temporaires. Le principal defi pour les formulateurs est de concilier beaute et respect du cheveu en developpant des produits inoffensifs et moins agressifs. Cet article decrit, dans un premier temps, le cheveu et le constituant responsable de sa couleur, la melanine, pour aborder ensuite les differents types de colorations capillaires ainsi que leur mode d’action.
{"title":"Cheveu, mélanine et colorations capillaires","authors":"Florian Laubé, V. Nardello-Rataj","doi":"10.51257/a-v1-j2305","DOIUrl":"https://doi.org/10.51257/a-v1-j2305","url":null,"abstract":"Que ce soit a la maison ou en salon de coiffure, de nombreuses personnes se colorent les cheveux. Une large gamme de produits, aux palettes de couleurs tres variees et a l’utilisation aisee, est proposee aux consommateurs. Ils ont le choix entre des colorations capillaires permanentes, semi-permanentes ou temporaires. Le principal defi pour les formulateurs est de concilier beaute et respect du cheveu en developpant des produits inoffensifs et moins agressifs. Cet article decrit, dans un premier temps, le cheveu et le constituant responsable de sa couleur, la melanine, pour aborder ensuite les differents types de colorations capillaires ainsi que leur mode d’action.","PeriodicalId":40024,"journal":{"name":"Recent Patents on Drug Delivery and Formulation","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90208551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-29DOI: 10.2174/187221131302190705100916
F. Acartürk
{"title":"Meet Our Editorial Board Member ","authors":"F. Acartürk","doi":"10.2174/187221131302190705100916","DOIUrl":"https://doi.org/10.2174/187221131302190705100916","url":null,"abstract":"","PeriodicalId":40024,"journal":{"name":"Recent Patents on Drug Delivery and Formulation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2174/187221131302190705100916","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48427604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-07-08DOI: 10.2174/187221131301190502152146
Stefano Giovagnoli
{"title":"Preface.","authors":"Stefano Giovagnoli","doi":"10.2174/187221131301190502152146","DOIUrl":"https://doi.org/10.2174/187221131301190502152146","url":null,"abstract":"","PeriodicalId":40024,"journal":{"name":"Recent Patents on Drug Delivery and Formulation","volume":"13 1 1","pages":"2"},"PeriodicalIF":0.0,"publicationDate":"2019-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2174/187221131301190502152146","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41964278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-07-08DOI: 10.2174/187221131301190502152046
C. Marianecci
{"title":"Meet Our Editorial Board Member","authors":"C. Marianecci","doi":"10.2174/187221131301190502152046","DOIUrl":"https://doi.org/10.2174/187221131301190502152046","url":null,"abstract":"","PeriodicalId":40024,"journal":{"name":"Recent Patents on Drug Delivery and Formulation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2174/187221131301190502152046","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47841499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L’Organisation Mondiale de la Sante (OMS) a rapporte qu’en 2016, 90 % des individus dans le monde vivaient dans des zones ne respectant pas ses lignes directrices en ce qui concerne la qualite de l’air. Les consommateurs, avertis des effets nefastes de la pollution de l'air sur l'apparence de la peau, s’orientent donc vers des cosmetiques revendiquant une protection anti-pollution. Apres un etat de l’art sur l’emergence du marche des cosmetiques anti-pollution, cet article presente les principaux polluants affectant l’apparence de la peau. Enfin, les mecanismes d’action de ces polluants au niveau cutane sont decrits afin d’identifier les cibles potentielles de soins cosmetiques antipollution.
{"title":"Actifs cosmétiques anti-pollution - Les polluants environnementaux et leur impact cutané","authors":"P. Burger, Hortense Plainfossé, X. Fernandez","doi":"10.51257/a-v1-j3006","DOIUrl":"https://doi.org/10.51257/a-v1-j3006","url":null,"abstract":"L’Organisation Mondiale de la Sante (OMS) a rapporte qu’en 2016, 90 % des individus dans le monde vivaient dans des zones ne respectant pas ses lignes directrices en ce qui concerne la qualite de l’air. Les consommateurs, avertis des effets nefastes de la pollution de l'air sur l'apparence de la peau, s’orientent donc vers des cosmetiques revendiquant une protection anti-pollution. Apres un etat de l’art sur l’emergence du marche des cosmetiques anti-pollution, cet article presente les principaux polluants affectant l’apparence de la peau. Enfin, les mecanismes d’action de ces polluants au niveau cutane sont decrits afin d’identifier les cibles potentielles de soins cosmetiques antipollution.","PeriodicalId":40024,"journal":{"name":"Recent Patents on Drug Delivery and Formulation","volume":"65 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83560851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Un point sur les methodes scientifiques permettant de valider l’activite anti-pollution d’ingredients cosmetiques est presente dans cet article. Une synthese des principaux ingredients naturels et synthetiques actuellement utilises est exposee ainsi que quelques exemples de formulations cosmetiques disponibles sur le marche.
{"title":"Actifs cosmétiques anti-pollution - Tests d’efficacité et formulations","authors":"P. Burger, Hortense Plainfossé, X. Fernandez","doi":"10.51257/a-v1-j3007","DOIUrl":"https://doi.org/10.51257/a-v1-j3007","url":null,"abstract":"Un point sur les methodes scientifiques permettant de valider l’activite anti-pollution d’ingredients cosmetiques est presente dans cet article. Une synthese des principaux ingredients naturels et synthetiques actuellement utilises est exposee ainsi que quelques exemples de formulations cosmetiques disponibles sur le marche.","PeriodicalId":40024,"journal":{"name":"Recent Patents on Drug Delivery and Formulation","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83185997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-03-11DOI: 10.2174/187221131204190212122056
G. Bonora
{"title":"Meet Our Editorial Board Member","authors":"G. Bonora","doi":"10.2174/187221131204190212122056","DOIUrl":"https://doi.org/10.2174/187221131204190212122056","url":null,"abstract":"","PeriodicalId":40024,"journal":{"name":"Recent Patents on Drug Delivery and Formulation","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2174/187221131204190212122056","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44107387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Le dynamisme du marche de l’aromatherapie est porte par l’engouement croissant pour les solutions naturelles en sante et bien-etre. Cependant, le developpement de produits d’aromatherapie peut s’averer complexe. Sans cadre reglementaire dedie aux huiles essentielles, la definition d’une strategie marketing et reglementaire est un prealable determinant pour tout futur produit. Pour etre moteur de l’innovation et repondre au defi d’avenir de l’aromatherapie, cet article, illustre d’exemples concrets, propose une approche pratique du developpement produit d’aromatherapie traitant des problematiques de formulation, d’ingredients et d’allegations, jusqu’a la strategie reglementaire adaptee.
{"title":"Aromathérapie - Formulation, développement, stratégies marketing et réglementaire","authors":"Mathieu Bouarfa","doi":"10.51257/a-v1-j2311","DOIUrl":"https://doi.org/10.51257/a-v1-j2311","url":null,"abstract":"Le dynamisme du marche de l’aromatherapie est porte par l’engouement croissant pour les solutions naturelles en sante et bien-etre. Cependant, le developpement de produits d’aromatherapie peut s’averer complexe. Sans cadre reglementaire dedie aux huiles essentielles, la definition d’une strategie marketing et reglementaire est un prealable determinant pour tout futur produit. Pour etre moteur de l’innovation et repondre au defi d’avenir de l’aromatherapie, cet article, illustre d’exemples concrets, propose une approche pratique du developpement produit d’aromatherapie traitant des problematiques de formulation, d’ingredients et d’allegations, jusqu’a la strategie reglementaire adaptee.","PeriodicalId":40024,"journal":{"name":"Recent Patents on Drug Delivery and Formulation","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89285812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Le dynamisme du marche de l’aromatherapie est porte par l’engouement croissant pour les solutions naturelles en sante et bien-etre. Bien que d’origine naturelle, les huiles essentielles, privees de definition legale, ne sont pas sans risque, et leur composition met au defi d’en tirer tout le potentiel. En vue d’y parvenir en aromatherapie, il est necessaire d’en maitriser la variabilite et de comprendre le maquis reglementaire applicable. Face au defi d’avenir de l’aromatherapie, cet article, illustre d’exemples, met en evidence les variations possibles de la composition des huiles essentielles et leurs usages therapeutiques, et s’interesse aux multiples statuts reglementaires idoines.
{"title":"Aromathérapie - Propriétés thérapeutiques et réglementation des huiles essentielles","authors":"Mathieu Bouarfa","doi":"10.51257/a-v1-j2309","DOIUrl":"https://doi.org/10.51257/a-v1-j2309","url":null,"abstract":"Le dynamisme du marche de l’aromatherapie est porte par l’engouement croissant pour les solutions naturelles en sante et bien-etre. Bien que d’origine naturelle, les huiles essentielles, privees de definition legale, ne sont pas sans risque, et leur composition met au defi d’en tirer tout le potentiel. En vue d’y parvenir en aromatherapie, il est necessaire d’en maitriser la variabilite et de comprendre le maquis reglementaire applicable. Face au defi d’avenir de l’aromatherapie, cet article, illustre d’exemples, met en evidence les variations possibles de la composition des huiles essentielles et leurs usages therapeutiques, et s’interesse aux multiples statuts reglementaires idoines.","PeriodicalId":40024,"journal":{"name":"Recent Patents on Drug Delivery and Formulation","volume":"53 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90361987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：