首页 > 最新文献

Coluna/ Columna最新文献

英文 中文
PROFILE OF PATIENTS WITH SPINE TUMOR OPERATED IN A SOUTH AMERICAN REFERENCE SERVICE. EPIDEMIOLOGICAL STUDY 南美一家参考服务机构脊柱肿瘤手术患者的概况。流行病学研究
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.1590/s1808-185120222104262528
Murilo Alexandre, William Zarza Santos, R. Mendonça, A. Gotfryd, M. F. Caffaro, R. Meves
ABSTRACT Objective: The objective was to conduct an analytical epidemiological study to understand the profile, treatment, and outcome of patients with spinal tumors in a Brazilian Quaternary Hospital of the SUS. Methods: A retrospective cohort analysis of data from the last five years was performed. It was described qualitative characteristics evaluated by absolute and relative frequencies and quantitative characteristics by sintetized measures. Associations between characteristics were verified using chi-square tests or exact tests. Results: 92 patients met the eligibility criteria. The mean age was 56.1 years (±14.7), with 48 men (52.2%) and 44 women (47.8%). The types of tumors organized in the three proposed groups had 19 multiple myelomas (20.7%), 62 metastases (67.3%), and 11 other tumors (12%). The neurological status measured through the ASIA score was A: 5.4%, B: 22.8%, C: 26.1%, D: 35.9%, E: 9.8%. Karnofsky was prevalent in the 50-70 range with 65.2%. The total hospitalization period had a mean of 22.8±18 days, preoperatively 11.9±9.2 days, and postoperatively 10.9±14 days. Karnofsky presented lower values according to the worst ASIA (p < 0.001). A total of 12 patients (13%) died during hospitalization. The total and postoperative length of stay was longer in patients who died (p = 0.002 and p < 0.001). Conclusions: This study provides epidemiological data that allow an understanding of the profile of patients with spinal tumors in the Brazilian Public Health System. The severity of the patients is higher when compared to most of the series cases in the literature. The patients with longer hospitalization stay died. Level of evidence IV; Case series.
目的:目的是开展一项分析流行病学研究,以了解SUS巴西第四医院脊柱肿瘤患者的概况、治疗和预后。方法:对近5年的资料进行回顾性队列分析。用绝对频率和相对频率评价其定性特征,用综合测度评价其定量特征。使用卡方检验或精确检验验证特征之间的关联。结果:92例患者符合入选标准。平均年龄56.1岁(±14.7岁),其中男性48例(52.2%),女性44例(47.8%)。三组患者的肿瘤类型分别为19例多发性骨髓瘤(20.7%)、62例转移瘤(67.3%)和11例其他肿瘤(12%)。通过ASIA评分测定的神经系统状态为A: 5.4%, B: 22.8%, C: 26.1%, D: 35.9%, E: 9.8%。Karnofsky在50-70的范围内普遍存在,占65.2%。总住院时间平均22.8±18天,术前11.9±9.2天,术后10.9±14天。Karnofsky表示,最差的ASIA值较低(p < 0.001)。12例患者(13%)在住院期间死亡。死亡患者的总住院时间和术后住院时间较长(p = 0.002和p < 0.001)。结论:本研究提供了流行病学数据,使人们能够了解巴西公共卫生系统中脊柱肿瘤患者的概况。与文献中大多数系列病例相比,患者的严重程度更高。住院时间较长的患者死亡。证据等级IV;病例系列。
{"title":"PROFILE OF PATIENTS WITH SPINE TUMOR OPERATED IN A SOUTH AMERICAN REFERENCE SERVICE. EPIDEMIOLOGICAL STUDY","authors":"Murilo Alexandre, William Zarza Santos, R. Mendonça, A. Gotfryd, M. F. Caffaro, R. Meves","doi":"10.1590/s1808-185120222104262528","DOIUrl":"https://doi.org/10.1590/s1808-185120222104262528","url":null,"abstract":"ABSTRACT Objective: The objective was to conduct an analytical epidemiological study to understand the profile, treatment, and outcome of patients with spinal tumors in a Brazilian Quaternary Hospital of the SUS. Methods: A retrospective cohort analysis of data from the last five years was performed. It was described qualitative characteristics evaluated by absolute and relative frequencies and quantitative characteristics by sintetized measures. Associations between characteristics were verified using chi-square tests or exact tests. Results: 92 patients met the eligibility criteria. The mean age was 56.1 years (±14.7), with 48 men (52.2%) and 44 women (47.8%). The types of tumors organized in the three proposed groups had 19 multiple myelomas (20.7%), 62 metastases (67.3%), and 11 other tumors (12%). The neurological status measured through the ASIA score was A: 5.4%, B: 22.8%, C: 26.1%, D: 35.9%, E: 9.8%. Karnofsky was prevalent in the 50-70 range with 65.2%. The total hospitalization period had a mean of 22.8±18 days, preoperatively 11.9±9.2 days, and postoperatively 10.9±14 days. Karnofsky presented lower values according to the worst ASIA (p < 0.001). A total of 12 patients (13%) died during hospitalization. The total and postoperative length of stay was longer in patients who died (p = 0.002 and p < 0.001). Conclusions: This study provides epidemiological data that allow an understanding of the profile of patients with spinal tumors in the Brazilian Public Health System. The severity of the patients is higher when compared to most of the series cases in the literature. The patients with longer hospitalization stay died. Level of evidence IV; Case series.","PeriodicalId":40025,"journal":{"name":"Coluna/ Columna","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67480192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THORACOLUMBAR FUSION IN THE UNIFIED HEALTH SYSTEM: PRE-COVID-19 TEMPORAL 统一卫生系统中的胸腰椎融合:covid -19前颞叶
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.1590/s1808-185120222102257395
Leticia Domingos Ronzani, Hannah Bang, K. S. Kock, Phelipe Menegaz, Rafael Olívio Martins, Martins Back Netto
ABSTRACT Objective: To evaluate the temporal trends of thoracolumbar fusion procedures performed by the United Health System in Brazil from 2009 to 2019. Methods: This was an observational ecological study based on data collected from the information systems under the aegis of DATASUS, especially the Hospital Information System, which manages the Hospital Admission Authorizations (Autorizações de Internação Hospitalar - AIHs). All patients who had undergone the procedures of interest, that is, elective and emergency short and long thoracolumbar arthrodeses, were included. The temporal trends of the procedures performed in Brazil and in its five regions were calculated using polynomial regression. Results: The temporal trend of elective thoracolumbar arthrodesis decreased, while that of emergency arthrodesis increased, with the peak in 2015, followed by a marked decline. Short fusions were more frequent in both elective and emergency modalities, and the South and Central-West Regions had the highest indices of procedures per million inhabitants during the entire 2009 to 2019 period. Conclusions: The temporal trends of thoracolumbar fusions performed by SUS have decreased over the last decade, a phenomenon which may be explained by the growing criticism of indications of the procedure in the current literature. Level of evidence III; Retrospective Comparative Study.
目的:评估2009年至2019年巴西联合卫生系统实施的胸腰椎融合手术的时间趋势。方法:这是一项观察性生态学研究,基于DATASUS支持下的信息系统,特别是管理住院许可的医院信息系统(Autorizações de interna o Hospitalar - AIHs)收集的数据。所有接受过相关手术的患者,即择期和急诊胸腰椎短段和长段关节融合术。使用多项式回归计算了在巴西及其五个地区执行的程序的时间趋势。结果:择期胸腰椎融合术的时间趋势下降,而急诊融合术的时间趋势上升,在2015年达到高峰,随后明显下降。短期融合在选择性和紧急模式下都更为频繁,2009年至2019年期间,南部和中西部地区每百万居民的程序指数最高。结论:在过去十年中,SUS进行胸腰椎融合的时间趋势有所下降,这一现象可能是由于当前文献中对该手术适应症的批评越来越多。证据等级III;回顾性比较研究。
{"title":"THORACOLUMBAR FUSION IN THE UNIFIED HEALTH SYSTEM: PRE-COVID-19 TEMPORAL","authors":"Leticia Domingos Ronzani, Hannah Bang, K. S. Kock, Phelipe Menegaz, Rafael Olívio Martins, Martins Back Netto","doi":"10.1590/s1808-185120222102257395","DOIUrl":"https://doi.org/10.1590/s1808-185120222102257395","url":null,"abstract":"ABSTRACT Objective: To evaluate the temporal trends of thoracolumbar fusion procedures performed by the United Health System in Brazil from 2009 to 2019. Methods: This was an observational ecological study based on data collected from the information systems under the aegis of DATASUS, especially the Hospital Information System, which manages the Hospital Admission Authorizations (Autorizações de Internação Hospitalar - AIHs). All patients who had undergone the procedures of interest, that is, elective and emergency short and long thoracolumbar arthrodeses, were included. The temporal trends of the procedures performed in Brazil and in its five regions were calculated using polynomial regression. Results: The temporal trend of elective thoracolumbar arthrodesis decreased, while that of emergency arthrodesis increased, with the peak in 2015, followed by a marked decline. Short fusions were more frequent in both elective and emergency modalities, and the South and Central-West Regions had the highest indices of procedures per million inhabitants during the entire 2009 to 2019 period. Conclusions: The temporal trends of thoracolumbar fusions performed by SUS have decreased over the last decade, a phenomenon which may be explained by the growing criticism of indications of the procedure in the current literature. Level of evidence III; Retrospective Comparative Study.","PeriodicalId":40025,"journal":{"name":"Coluna/ Columna","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67479310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SPINOPELVIC PARAMETERS AFTER POSTERIOR LUMBAR ARTHRODESIS IN DEGENERATIVE SPINAL DISEASES 退行性脊柱疾病后路腰椎融合术后的脊柱骨盆参数
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.1590/s1808-185120222102258229
Julio Alves Ponte, Alderico Girão Campos de Barros, G. Almeida, Luiz Eduardo Carelli Teixeira da Silva, Eduardo Branco de Sousa
ABSTRACT Introduction: Spinopelvic parameters related to sagittal balance have become increasinglyimportantamong spine surgeons due to their correlation with patient satisfaction rates. Objective: The goal of this study was to evaluate changes in spinal sagittal balance after lumbar spine surgery using PLIF, the posterior lumbar interbody fusion technique. Methods: The sample consisted of adult patients with degenerative spinal disease submitted to posterior lumbar arthrodesis. Patients between 18 and 70 years of agewho underwent surgeryfrom 2015 to 2017 were included in the study and divided into short (1 level) and long arthrodesis (2 to 4 levels) groups. Radiographic analysis of the spinopelvic parameters, measured before and after lumbar arthrodesis, was conducted using the SURGIMAP software. Then we evaluated the variation between pre- and postoperative measurements and performed correlation and linear regression analyses between the parameters. Results: The sample was composed of 80 patients (48 men). The mean age was lower in the short arthrodesis group than in the long arthrodesis group (52.67 ± 9.66 years versus 59.37 ± 9.30 years, respectively; p<0.0025). Significant variations in lumbar lordosis, pelvic tilt, sagittal vertical axis, T1 pelvic angle, and pelvic incidence minus lumbar lordosis were found in both short and long arthrodesis groups. The variation was significantly larger in the long than in the short arthrodesis group. Conclusion: In adult degenerative spine disease, short and long arthrodesis of the lumbar spine by PLIF allows correction of the spinopelvic parameters. Level of evidence III; Retrospective, comparative study.
摘要:由于与患者满意度相关,与矢状面平衡相关的脊柱骨盆参数在脊柱外科医生中变得越来越重要。目的:本研究的目的是评估使用PLIF(后路腰椎椎体间融合技术)腰椎手术后脊柱矢状平衡的变化。方法:样本包括接受后路腰椎关节融合术的退行性脊柱疾病的成年患者。研究纳入了2015年至2017年接受手术的年龄在18岁至70岁之间的患者,并分为短节段(1节段)和长节段(2至4节段)组。使用SURGIMAP软件对腰椎融合术前后测量的椎盂参数进行影像学分析。然后我们评估术前和术后测量值之间的差异,并对参数进行相关和线性回归分析。结果:样本由80例患者组成,其中男性48例。短关节融合术组的平均年龄低于长关节融合术组(52.67±9.66岁vs 59.37±9.30岁);p < 0.0025)。在短关节融合术组和长关节融合术组中,腰椎前凸、骨盆倾斜、矢状垂直轴、T1骨盆角和骨盆发生率减去腰椎前凸均有显著变化。长关节融合术组的差异明显大于短关节融合术组。结论:在成人退行性脊柱疾病中,通过PLIF进行腰椎短、长关节融合术可以矫正脊柱骨盆参数。证据等级III;回顾性比较研究。
{"title":"SPINOPELVIC PARAMETERS AFTER POSTERIOR LUMBAR ARTHRODESIS IN DEGENERATIVE SPINAL DISEASES","authors":"Julio Alves Ponte, Alderico Girão Campos de Barros, G. Almeida, Luiz Eduardo Carelli Teixeira da Silva, Eduardo Branco de Sousa","doi":"10.1590/s1808-185120222102258229","DOIUrl":"https://doi.org/10.1590/s1808-185120222102258229","url":null,"abstract":"ABSTRACT Introduction: Spinopelvic parameters related to sagittal balance have become increasinglyimportantamong spine surgeons due to their correlation with patient satisfaction rates. Objective: The goal of this study was to evaluate changes in spinal sagittal balance after lumbar spine surgery using PLIF, the posterior lumbar interbody fusion technique. Methods: The sample consisted of adult patients with degenerative spinal disease submitted to posterior lumbar arthrodesis. Patients between 18 and 70 years of agewho underwent surgeryfrom 2015 to 2017 were included in the study and divided into short (1 level) and long arthrodesis (2 to 4 levels) groups. Radiographic analysis of the spinopelvic parameters, measured before and after lumbar arthrodesis, was conducted using the SURGIMAP software. Then we evaluated the variation between pre- and postoperative measurements and performed correlation and linear regression analyses between the parameters. Results: The sample was composed of 80 patients (48 men). The mean age was lower in the short arthrodesis group than in the long arthrodesis group (52.67 ± 9.66 years versus 59.37 ± 9.30 years, respectively; p<0.0025). Significant variations in lumbar lordosis, pelvic tilt, sagittal vertical axis, T1 pelvic angle, and pelvic incidence minus lumbar lordosis were found in both short and long arthrodesis groups. The variation was significantly larger in the long than in the short arthrodesis group. Conclusion: In adult degenerative spine disease, short and long arthrodesis of the lumbar spine by PLIF allows correction of the spinopelvic parameters. Level of evidence III; Retrospective, comparative study.","PeriodicalId":40025,"journal":{"name":"Coluna/ Columna","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67479551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
LONG-TERM USE OF DENOSUMAB IN GIANT CELL TUMORS AND VERTEBRAL ANEURYSMAL BONE CYSTS 地诺单抗在巨细胞瘤和椎动脉瘤性骨囊肿中的长期应用
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.1590/s1808-185120222101253789
P. Bazán, Micaela Cinalli, Felipe Lanari Zabiaur, R. Castelli, C. Silveri, José Luis Monayer, Enrique Gobbi, A. Steverlynck
ABSTRACT Introduction: Denosumab is a human monoclonal antibody that binds to the receptor activator of nuclear factor kB (RANKL), it is used in the treatment of Osteoporosis. The Giant Cell Tumor (GCT) and the Aneurysmal Bone Cyst (ABC) use the same RANKL, and for this reason this drug began to be used for its treatment. There is consensus on the use, dose-time and 12-month duration for Denosumab treatment of GCT. Not so for ABC. In unresectable, disabling or recurrent tumors, its use could be for life. The adverse events of the habitual use of the drug are known, but it is not known if these increase with time. The objective of the present work is to identify the possible adverse events of treatment with Denosumab for more than 12 months. Material and Method: Series of cases with a diagnosis of GCT or ABC in spine, treated with Denosumab for more than 12 months. Adverse events are: arthralgia, fatigue, spinal pain, pain in extremities, headache, hypokalaemia, hypocalcemia, osteonecrosis of the jaw, malignant transformation, pathological fractures. Results: Eight patients, 6 TCG and 2 ABC, with a mean age at diagnosis of 25,6 years; presenting a mean treatment of 4.18 years (range 1.7 - 8.7). Of 6 operated patients, 4 had recurrence (2 to 36 months after surgery). One patient had to suspend treatment due to necrosis of the jaw, another hypocalcemia, both returned to treatment when stabilized. Conclusions: A minor adverse event (hypocalcemia) and a major adverse event (jaw bone necrosis) were observed. Level of Evidence IV; Original.
摘要简介:Denosumab是一种结合核因子kB受体激活剂(RANKL)的人单克隆抗体,用于治疗骨质疏松症。巨细胞瘤(GCT)和动脉瘤性骨囊肿(ABC)使用相同的RANKL,因此这种药物开始用于治疗巨细胞瘤。对于Denosumab治疗GCT的使用、剂量时间和12个月的持续时间有共识。但ABC却不是这样。对于无法切除、致残或复发的肿瘤,它的使用可能是终身的。习惯性使用该药的不良事件是已知的,但不知道这些不良事件是否随着时间的推移而增加。本研究的目的是确定使用Denosumab治疗超过12个月可能出现的不良事件。材料与方法:诊断为脊柱GCT或ABC的病例系列,用Denosumab治疗12个月以上。不良事件有:关节痛、疲劳、脊柱痛、四肢痛、头痛、低钾血症、低钙血症、颌骨骨坏死、恶性转化、病理性骨折。结果:8例患者,TCG 6例,ABC 2例,平均诊断年龄25.6岁;平均治疗时间为4.18年(范围1.7 - 8.7)。6例手术患者中,4例术后2 ~ 36个月复发。一名患者因颌骨坏死而暂停治疗,另一名患者因低钙血症而暂停治疗,两人均在病情稳定后恢复治疗。结论:观察到轻微不良事件(低钙血症)和主要不良事件(颌骨坏死)。证据水平IV;原创。
{"title":"LONG-TERM USE OF DENOSUMAB IN GIANT CELL TUMORS AND VERTEBRAL ANEURYSMAL BONE CYSTS","authors":"P. Bazán, Micaela Cinalli, Felipe Lanari Zabiaur, R. Castelli, C. Silveri, José Luis Monayer, Enrique Gobbi, A. Steverlynck","doi":"10.1590/s1808-185120222101253789","DOIUrl":"https://doi.org/10.1590/s1808-185120222101253789","url":null,"abstract":"ABSTRACT Introduction: Denosumab is a human monoclonal antibody that binds to the receptor activator of nuclear factor kB (RANKL), it is used in the treatment of Osteoporosis. The Giant Cell Tumor (GCT) and the Aneurysmal Bone Cyst (ABC) use the same RANKL, and for this reason this drug began to be used for its treatment. There is consensus on the use, dose-time and 12-month duration for Denosumab treatment of GCT. Not so for ABC. In unresectable, disabling or recurrent tumors, its use could be for life. The adverse events of the habitual use of the drug are known, but it is not known if these increase with time. The objective of the present work is to identify the possible adverse events of treatment with Denosumab for more than 12 months. Material and Method: Series of cases with a diagnosis of GCT or ABC in spine, treated with Denosumab for more than 12 months. Adverse events are: arthralgia, fatigue, spinal pain, pain in extremities, headache, hypokalaemia, hypocalcemia, osteonecrosis of the jaw, malignant transformation, pathological fractures. Results: Eight patients, 6 TCG and 2 ABC, with a mean age at diagnosis of 25,6 years; presenting a mean treatment of 4.18 years (range 1.7 - 8.7). Of 6 operated patients, 4 had recurrence (2 to 36 months after surgery). One patient had to suspend treatment due to necrosis of the jaw, another hypocalcemia, both returned to treatment when stabilized. Conclusions: A minor adverse event (hypocalcemia) and a major adverse event (jaw bone necrosis) were observed. Level of Evidence IV; Original.","PeriodicalId":40025,"journal":{"name":"Coluna/ Columna","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67478963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
PRE- AND POSTOPERATIVE COMPARATIVE ANALYSIS OF THE SPINOPELVIC AND GLOBAL SAGITTAL PARAMETERS OF PATIENTS WITH ADOLESCENT IDIOPATHIC SCOLIOSIS 青少年特发性脊柱侧凸患者脊柱骨盆和整体矢状面参数术前和术后的比较分析
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.1590/s1808-185120222101250514
Anderson Fellipe Matos de Souza, L. M. Ávila, C. A. Aguiar, Luís Eduardo Munhoz da Rocha
ABSTRACT Objective: To analyze the pre- and postoperative spinopelvic parameters and global sagittal balance of patients with adolescent idiopathic scoliosis (AIS) divided into 3 groups (Group 1 – thoracic arthrodesis, Group 2 - thoracolumbar arthrodesis, and Group 3 – lumbar arthrodesis), observing differences in these two moments and whether the parameter values are maintained or not over a period of up to 2 years following surgery. Methods: We analyzed the radiographs from a single-center database of 99 patients who underwent arthrodesis with posterior instrumentation. Pelvic incidence, pelvic version, sacral slope, lumbar lordosis, thoracic kyphosis, and sagittal vertical axis values were measured in the pre- and postoperative radiographies of each patient. Results: The parameters of pelvic incidence, pelvic version, sacral slope, and sagittal vertical axis did not show statistically significant differences among the 3 groups. There was a difference in preoperative lumbar lordosis between the 3 groups (p = 0.049). Thoracic kyphosis showed differences both in the pre- (p = 0.015) and postoperative (p = 0.042) values, in addition to demonstrating a relationship of dependence between the pre- and postoperative values in the final statistical analysis. Conclusion: The evaluation of the parameters analyzed shows that the study groups have similar values of individual balance, with the exception of thoracic kyphosis and lumbar lordosis, which are measurements that depend on the surgical technique and compensatory mechanisms, but remained within normal ranges. These factors allow the surgeon to be attentive to both the coronal and sagittal planes when planning the correction in order to achieve the equilibrium of the trunk in addition to correction of the deformity. Level of Evidence IIIA: Comparative retrospective study.
摘要目的:将青少年特发性脊柱侧凸(AIS)患者分为3组(1组-胸椎融合术、2组-胸腰椎融合术和3组-腰椎融合术),分析其术前和术后椎盂参数和整体矢状平衡,观察这两个时刻的差异,以及这些参数值在术后2年内是否保持。方法:我们分析了99例接受后路内固定关节融合术患者的单中心数据库的x线片。在每位患者的术前和术后x线片上测量骨盆发生率、骨盆形态、骶骨坡度、腰椎前凸、胸后凸和矢状垂直轴值。结果:3组患者盆腔发生率、盆腔形态、骶骨坡度、矢状垂直轴等参数差异无统计学意义。3组术前腰椎前凸比较差异有统计学意义(p = 0.049)。胸后凸在术前值(p = 0.015)和术后值(p = 0.042)均有差异,并在最终的统计分析中显示了术前值和术后值之间的依赖关系。结论:对所分析参数的评估显示,研究组的个体平衡值相似,除了胸后凸和腰椎前凸,这是依赖于手术技术和代偿机制的测量值,但仍在正常范围内。这些因素使外科医生在计划矫正时既要注意冠状面又要注意矢状面,以便在矫正畸形的同时达到躯干的平衡。证据水平IIIA:比较回顾性研究。
{"title":"PRE- AND POSTOPERATIVE COMPARATIVE ANALYSIS OF THE SPINOPELVIC AND GLOBAL SAGITTAL PARAMETERS OF PATIENTS WITH ADOLESCENT IDIOPATHIC SCOLIOSIS","authors":"Anderson Fellipe Matos de Souza, L. M. Ávila, C. A. Aguiar, Luís Eduardo Munhoz da Rocha","doi":"10.1590/s1808-185120222101250514","DOIUrl":"https://doi.org/10.1590/s1808-185120222101250514","url":null,"abstract":"ABSTRACT Objective: To analyze the pre- and postoperative spinopelvic parameters and global sagittal balance of patients with adolescent idiopathic scoliosis (AIS) divided into 3 groups (Group 1 – thoracic arthrodesis, Group 2 - thoracolumbar arthrodesis, and Group 3 – lumbar arthrodesis), observing differences in these two moments and whether the parameter values are maintained or not over a period of up to 2 years following surgery. Methods: We analyzed the radiographs from a single-center database of 99 patients who underwent arthrodesis with posterior instrumentation. Pelvic incidence, pelvic version, sacral slope, lumbar lordosis, thoracic kyphosis, and sagittal vertical axis values were measured in the pre- and postoperative radiographies of each patient. Results: The parameters of pelvic incidence, pelvic version, sacral slope, and sagittal vertical axis did not show statistically significant differences among the 3 groups. There was a difference in preoperative lumbar lordosis between the 3 groups (p = 0.049). Thoracic kyphosis showed differences both in the pre- (p = 0.015) and postoperative (p = 0.042) values, in addition to demonstrating a relationship of dependence between the pre- and postoperative values in the final statistical analysis. Conclusion: The evaluation of the parameters analyzed shows that the study groups have similar values of individual balance, with the exception of thoracic kyphosis and lumbar lordosis, which are measurements that depend on the surgical technique and compensatory mechanisms, but remained within normal ranges. These factors allow the surgeon to be attentive to both the coronal and sagittal planes when planning the correction in order to achieve the equilibrium of the trunk in addition to correction of the deformity. Level of Evidence IIIA: Comparative retrospective study.","PeriodicalId":40025,"journal":{"name":"Coluna/ Columna","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67479056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE USE OF CHEMOPROPHYLAXIS OR NOT FOR DVT IN SPINE SURGERY: A SYSTEMATIC REVIEW 在脊柱手术中是否使用化学预防治疗深静脉血栓:一项系统综述
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.1590/s1808-185120222102258863
Bruno Landal Cavassin, Carolina Cabral Brandalizze, Gabriel Wielisvky Rocha, L. M. Garbers, S. Kusma, Fernando Borge Teixeira, E. Vialle, L. Vialle
ABSTRACT Objective: To compare pharmacological and non-pharmacological prophylaxis in elective spine surgery to determine the risks of DVT, PTE, and epidural hematoma (EH) in both groups, as well as their respective treatment effectiveness. Methods: Systematic review and meta-analysis based on systematically searched articles, using combinations of MeSH terms related to chemoprophylaxis and non-chemoprophylaxis for prevention of deep vein thrombosis and pulmonary embolism in elective spine surgery. Adult patients were eligible for inclusion in the study, except for those with trauma, spinal cord injury, neoplasms, or those using vena cava filters. Results: Five studies were selected for this systematic review and meta-analysis: 3 retrospective studies, 1 prospective study, and 1 case series. Data analysis showed that 4.64% of patients treated with chemoprophylaxis had an unfavorable outcome regarding DVT, while this outcome occurred in 1.14% of patients not treated with chemoprophylaxis (p=0.001). Among patients using chemoprophylaxis, only 0.1% developed epidural hematoma and 0.38% developed PTE. Among those on non-pharmaceutical prophylaxis, 0.04% had EH (p=0.11) and 0.42% had PTE (p=0.45). Conclusions: No benefits were found for chemoprophylaxis as compared to non-chemoprophylaxis in preventing DVT in elective spine surgery, nor was there an increased risk of epidural hematoma or fatal thromboembolic events. Level of evidence III; Therapeutic studies; Investigation of treatment results.
目的:比较选择性脊柱手术的药物和非药物预防,以确定两组患者发生DVT、PTE和硬膜外血肿(EH)的风险,以及各自的治疗效果。方法:系统回顾和meta分析基于系统检索的文章,结合使用与化疗预防和非化疗预防相关的MeSH术语预防选择性脊柱手术中深静脉血栓形成和肺栓塞。除创伤、脊髓损伤、肿瘤或使用腔静脉过滤器的患者外,成年患者有资格纳入研究。结果:本系统评价和荟萃分析选择了5项研究:3项回顾性研究,1项前瞻性研究和1个病例系列。数据分析显示,4.64%接受化学预防治疗的患者在DVT方面出现不良结果,而未接受化学预防治疗的患者出现不良结果的比例为1.14% (p=0.001)。采用化学预防的患者发生硬膜外血肿的比例为0.1%,发生PTE的比例为0.38%,而采用非药物预防的患者发生EH的比例为0.04% (p=0.11),发生PTE的比例为0.42% (p=0.45)。结论:与非化学预防相比,化学预防在预防选择性脊柱手术DVT方面没有发现益处,也没有增加硬膜外血肿或致命血栓栓塞事件的风险。证据等级III;治疗研究;治疗结果调查。
{"title":"THE USE OF CHEMOPROPHYLAXIS OR NOT FOR DVT IN SPINE SURGERY: A SYSTEMATIC REVIEW","authors":"Bruno Landal Cavassin, Carolina Cabral Brandalizze, Gabriel Wielisvky Rocha, L. M. Garbers, S. Kusma, Fernando Borge Teixeira, E. Vialle, L. Vialle","doi":"10.1590/s1808-185120222102258863","DOIUrl":"https://doi.org/10.1590/s1808-185120222102258863","url":null,"abstract":"ABSTRACT Objective: To compare pharmacological and non-pharmacological prophylaxis in elective spine surgery to determine the risks of DVT, PTE, and epidural hematoma (EH) in both groups, as well as their respective treatment effectiveness. Methods: Systematic review and meta-analysis based on systematically searched articles, using combinations of MeSH terms related to chemoprophylaxis and non-chemoprophylaxis for prevention of deep vein thrombosis and pulmonary embolism in elective spine surgery. Adult patients were eligible for inclusion in the study, except for those with trauma, spinal cord injury, neoplasms, or those using vena cava filters. Results: Five studies were selected for this systematic review and meta-analysis: 3 retrospective studies, 1 prospective study, and 1 case series. Data analysis showed that 4.64% of patients treated with chemoprophylaxis had an unfavorable outcome regarding DVT, while this outcome occurred in 1.14% of patients not treated with chemoprophylaxis (p=0.001). Among patients using chemoprophylaxis, only 0.1% developed epidural hematoma and 0.38% developed PTE. Among those on non-pharmaceutical prophylaxis, 0.04% had EH (p=0.11) and 0.42% had PTE (p=0.45). Conclusions: No benefits were found for chemoprophylaxis as compared to non-chemoprophylaxis in preventing DVT in elective spine surgery, nor was there an increased risk of epidural hematoma or fatal thromboembolic events. Level of evidence III; Therapeutic studies; Investigation of treatment results.","PeriodicalId":40025,"journal":{"name":"Coluna/ Columna","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67479186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ENDOSCOPIC INTERLAMINAR SPINE SURGERY GUIDED BY PORTABLE ULTRASOUND: A NEW TECHNIQUE 便携式超声引导下的椎板间内窥镜手术:一项新技术
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.1590/s1808-185120222102260083
D. Giubilei, D. Santos, Monres Jose Gomes, Marcio Oliveira Penna de Carvalho
ABSTRACT This paper describes the technique of interlaminar endoscopic surgery guided by a portable ultrasound device. This innovation allows endoscopic surgery to be performed without the use of real-time radiography, which is associated with a higher risk of radiation damage. The portable wireless ultrasound device used for this technique, which has not been yet described in the world literature for minimally invasive surgeries, can be used as an imaging tool to delimit the interlaminar space in minimally invasive surgeries via both transverse and sagittal views. Level of evidence I; Quality of evidence A.
摘要本文介绍了一种便携式超声装置引导下的层间内镜手术技术。这一创新使得内窥镜手术可以在不使用实时放射照相的情况下进行,而实时放射照相会带来更高的辐射损伤风险。用于该技术的便携式无线超声设备,在世界微创手术文献中尚未描述,可作为微创手术中通过横切面和矢状面划分层间空间的成像工具。证据等级I;证据质量A。
{"title":"ENDOSCOPIC INTERLAMINAR SPINE SURGERY GUIDED BY PORTABLE ULTRASOUND: A NEW TECHNIQUE","authors":"D. Giubilei, D. Santos, Monres Jose Gomes, Marcio Oliveira Penna de Carvalho","doi":"10.1590/s1808-185120222102260083","DOIUrl":"https://doi.org/10.1590/s1808-185120222102260083","url":null,"abstract":"ABSTRACT This paper describes the technique of interlaminar endoscopic surgery guided by a portable ultrasound device. This innovation allows endoscopic surgery to be performed without the use of real-time radiography, which is associated with a higher risk of radiation damage. The portable wireless ultrasound device used for this technique, which has not been yet described in the world literature for minimally invasive surgeries, can be used as an imaging tool to delimit the interlaminar space in minimally invasive surgeries via both transverse and sagittal views. Level of evidence I; Quality of evidence A.","PeriodicalId":40025,"journal":{"name":"Coluna/ Columna","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67479192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE PREVALENCE OF LOW BACK PAIN IN NURSES AT A UNIVERSITY HOSPITAL IN THE EASTERN AREA OF SÃO PAULO 在东部地区sÃo保罗大学医院的护士腰痛的流行
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.1590/s1808-185120222102262474
Felipe Ramalho Guedes, Fernanda Andrea Minutti Navarro, Rodrigo Yuiti Nakao, I. Franco, L. Rodrigues
ABSTRACT Objective: To evaluate the prevalence of low back pain in nurses at a university hospital in São Paulo and establish a relationship with social aspects. Methods: A cross-sectional study was carried out, through the application of a questionnaire containing social questions(weight, age, height, work sector, working hours, physical activity, presence and frequency of low back pain) in addition to the Oswestry questionnaire. Results: One hundred fifty-three nurses participated in the study. Of these, 92.30% of the women and 73.91% of the men presented low back pain, with a third classifying the pain as sporadic. In relation to BMI, pain is lower in those who are underweight (60%) and higher among those who are overweight (96.77%). Most of the sample was sedentary (66%), and of these, 96% had low back pain. There was no difference in the comparison by working hours, in relation to work sector, pain was more present in the following sectors: coordination (100%); children’s ward (92%); adult emergency room (90%) and adult ICU (31%). Thirty nurses worked double shifts, and of these, 90% reported low back pain, while among those who worked only at the university hospital, 89.4% reported pain. In relation to working hours, the longer the working day, the greater the pain. In the function assessment (Oswestry), 99 participants obtained a value of up to 30% disability. Conclusion: Based on the results of this work, it is concluded that there is a high prevalence of low back pain in nurses at the Hospital Universitário; however, it was not possible to determine a direct risk factor associated with this high prevalence. Level of Evidence IV; Cross-sectional study.
摘要目的:了解圣保罗某大学医院护士腰痛的患病率,并建立与社会方面的关系。方法:采用横断面研究,在Oswestry问卷的基础上,应用包含社会问题(体重、年龄、身高、工作部门、工作时间、体力活动、腰痛的存在和频率)的问卷进行研究。结果:153名护士参与了本研究。其中,92.30%的女性和73.91%的男性表现出腰痛,三分之一的人将疼痛归类为偶发性疼痛。相对于BMI,体重过轻的人(60%)的疼痛程度较低,而超重的人(96.77%)的疼痛程度较高。大多数样本是久坐不动的(66%),其中96%有腰痛。按工作时间进行比较没有差异,就工作部门而言,以下部门的痛苦程度更高:协调(100%);儿童病房(92%);成人急诊室(90%)和成人ICU(31%)。30名护士轮班工作,其中90%的人报告腰痛,而在那些只在大学医院工作的人中,89.4%的人报告腰痛。就工作时间而言,工作日越长,疼痛越大。在功能评估(Oswestry)中,99名参与者获得了高达30%的残疾值。结论:根据本工作的结果,得出结论:该医院护士腰痛的患病率较高Universitário;然而,不可能确定与这种高患病率相关的直接危险因素。证据水平IV;横断面研究。
{"title":"THE PREVALENCE OF LOW BACK PAIN IN NURSES AT A UNIVERSITY HOSPITAL IN THE EASTERN AREA OF SÃO PAULO","authors":"Felipe Ramalho Guedes, Fernanda Andrea Minutti Navarro, Rodrigo Yuiti Nakao, I. Franco, L. Rodrigues","doi":"10.1590/s1808-185120222102262474","DOIUrl":"https://doi.org/10.1590/s1808-185120222102262474","url":null,"abstract":"ABSTRACT Objective: To evaluate the prevalence of low back pain in nurses at a university hospital in São Paulo and establish a relationship with social aspects. Methods: A cross-sectional study was carried out, through the application of a questionnaire containing social questions(weight, age, height, work sector, working hours, physical activity, presence and frequency of low back pain) in addition to the Oswestry questionnaire. Results: One hundred fifty-three nurses participated in the study. Of these, 92.30% of the women and 73.91% of the men presented low back pain, with a third classifying the pain as sporadic. In relation to BMI, pain is lower in those who are underweight (60%) and higher among those who are overweight (96.77%). Most of the sample was sedentary (66%), and of these, 96% had low back pain. There was no difference in the comparison by working hours, in relation to work sector, pain was more present in the following sectors: coordination (100%); children’s ward (92%); adult emergency room (90%) and adult ICU (31%). Thirty nurses worked double shifts, and of these, 90% reported low back pain, while among those who worked only at the university hospital, 89.4% reported pain. In relation to working hours, the longer the working day, the greater the pain. In the function assessment (Oswestry), 99 participants obtained a value of up to 30% disability. Conclusion: Based on the results of this work, it is concluded that there is a high prevalence of low back pain in nurses at the Hospital Universitário; however, it was not possible to determine a direct risk factor associated with this high prevalence. Level of Evidence IV; Cross-sectional study.","PeriodicalId":40025,"journal":{"name":"Coluna/ Columna","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67479270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
COMPARISON BETWEEN TWO METHODS OF MEASURING PELVIC OBLIQUITY IN CEREBRAL PALSY AND MYELOMENINGOCELE 脑瘫和脊髓脊膜膨出两种测量骨盆倾角的方法比较
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.1590/s1808-185120222103147809
Marcus Vinicius Brito Marques, Sylvio Mistro Neto, Roberto Rossanez, P. Cavali, A. Rossato, Elcio Landim, Marcelo ítalo Risso Neto
ABSTRACT Objective: To evaluate the intra- and inter-observer reproducibility of the evaluation of the pelvic obliquity (PO) in patients with neuro-muscular deformities via the method that uses the iliac crests and the method that uses the upper endplate of S1 and to determine whe ther there is a relationship between the methods. Methods: The digitized panoramic radiographies of thirty patients with cerebral paralysis or myelomeningocelein outpatient monitoring were evaluated by four examiners: two experienced spinal surgeons and two fellows. Two radiographs were excluded because analysis was impossible. All exams were obtained in accordance with the periodic monitoring protocol in the sitting position, using digitized film and a film-focus distance of 110 cm Results: High intra- and inter-observer agreement was observed both for method that uses the iliac crests and the method that evaluates the S1 endplate. However, no significant relationship between the two methods was observed. Conclusions: The methods evaluated had good reproducibility and agreement among the observers. It was confirmed that, on account of the existent linear relation, it is possible to estimate the value of the iliac crest method knowing the value obtained by the S1 plateau multiplied by 0.76. There was no agreement between the iliac crest and S1 plateau PO evaluation methods. Level of evidence IV; Retrospective cross-sectional study.
【摘要】目的:评价髂嵴法和骶S1上终板法评估神经肌肉畸形患者骨盆倾角(PO)的观察者内和观察者间的可重复性,并确定两者之间是否存在相关性。方法:由2名经验丰富的脊柱外科医生和2名研究员对30例门诊监测的脑瘫或脊髓脊膜明胶患者的数字化全景x线片进行评价。由于无法进行分析,两张x光片被排除在外。所有检查均按照坐位定期监测方案进行,使用数字化胶片,胶片聚焦距离为110 cm。结果:使用髂骨嵴的方法和评估S1终板的方法均观察到高度的观察者内部和观察者之间的一致性。然而,两种方法之间没有明显的关系。结论:所评价的方法具有良好的再现性和观察者之间的一致性。证实了由于存在线性关系,用S1平台值乘以0.76就可以估计出髂嵴法的值。髂嵴和S1平台的PO评价方法不一致。证据等级IV;回顾性横断面研究。
{"title":"COMPARISON BETWEEN TWO METHODS OF MEASURING PELVIC OBLIQUITY IN CEREBRAL PALSY AND MYELOMENINGOCELE","authors":"Marcus Vinicius Brito Marques, Sylvio Mistro Neto, Roberto Rossanez, P. Cavali, A. Rossato, Elcio Landim, Marcelo ítalo Risso Neto","doi":"10.1590/s1808-185120222103147809","DOIUrl":"https://doi.org/10.1590/s1808-185120222103147809","url":null,"abstract":"ABSTRACT Objective: To evaluate the intra- and inter-observer reproducibility of the evaluation of the pelvic obliquity (PO) in patients with neuro-muscular deformities via the method that uses the iliac crests and the method that uses the upper endplate of S1 and to determine whe ther there is a relationship between the methods. Methods: The digitized panoramic radiographies of thirty patients with cerebral paralysis or myelomeningocelein outpatient monitoring were evaluated by four examiners: two experienced spinal surgeons and two fellows. Two radiographs were excluded because analysis was impossible. All exams were obtained in accordance with the periodic monitoring protocol in the sitting position, using digitized film and a film-focus distance of 110 cm Results: High intra- and inter-observer agreement was observed both for method that uses the iliac crests and the method that evaluates the S1 endplate. However, no significant relationship between the two methods was observed. Conclusions: The methods evaluated had good reproducibility and agreement among the observers. It was confirmed that, on account of the existent linear relation, it is possible to estimate the value of the iliac crest method knowing the value obtained by the S1 plateau multiplied by 0.76. There was no agreement between the iliac crest and S1 plateau PO evaluation methods. Level of evidence IV; Retrospective cross-sectional study.","PeriodicalId":40025,"journal":{"name":"Coluna/ Columna","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67479314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
EFFECT OF TIME UNTIL DECOMPRESSION ON NEUROLOGIC RECOVERY AFTER SPINAL CORD INJURY 脊髓损伤后减压时间对神经功能恢复的影响
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.1590/s1808-185120222103265129
E. A. Iunes, F. Onishi, H. R. D. Costa, Thiago Leonardi Azuaga
ABSTRACT Spinal cord injuries can have serious consequences for the individual, such as loss of motor function, sensory impairment, and alteration of physiological systems functions. Treatments for spinal cord injuries involve the use of drugs and surgical approaches. In the surgical field, there is a question about the ideal time after the trauma to perform the surgical procedure. The studies divide the time until surgery after the injury into two categories: “early” and “late”. To review the scientific literature on this topic, and to assess the relative effectiveness of early versus late decompressive surgery, we considered early intervention up to 24 hours and late intervention from 24 hours after the injury. For this, we performed a literature review and selected retrospective, prospective observational studies, clinical studies, and reviews with meta-analysis that compared the recovery time of patients with spinal cord injury after surgeries performed within 24 hours (early) and after 24 hours (late). The results showed potential for neurological improvement with early or even ultra-early surgical decompression (up to 12 hours) in patients with traumatic cervical spinal cord injury. On the other hand, reports about the advantage of early decompression when there is a thoracic injury are scarce. In addition to the time to decompression, the concomitant use of some drugs seems to play an important role in patients’ recovery. Level of Evidence II; Literature review.
脊髓损伤可对个体造成严重后果,如运动功能丧失、感觉损伤和生理系统功能改变。脊髓损伤的治疗包括使用药物和手术方法。在外科领域,有一个关于创伤后进行手术的理想时间的问题。研究将受伤后手术前的时间分为两类:“早期”和“晚期”。为了回顾有关该主题的科学文献,并评估早期与晚期减压手术的相对有效性,我们考虑了损伤后24小时的早期干预和24小时后的晚期干预。为此,我们进行了文献综述,并选择了回顾性、前瞻性观察性研究、临床研究和meta分析综述,比较了脊髓损伤患者术后24小时内(早期)和24小时后(晚期)的恢复时间。结果显示,外伤性颈脊髓损伤患者早期甚至超早期手术减压(长达12小时)有可能改善神经系统。另一方面,关于胸椎损伤后早期减压优势的报道很少。除了减压的时间外,一些药物的同时使用似乎对患者的康复起着重要的作用。证据水平II;文献综述。
{"title":"EFFECT OF TIME UNTIL DECOMPRESSION ON NEUROLOGIC RECOVERY AFTER SPINAL CORD INJURY","authors":"E. A. Iunes, F. Onishi, H. R. D. Costa, Thiago Leonardi Azuaga","doi":"10.1590/s1808-185120222103265129","DOIUrl":"https://doi.org/10.1590/s1808-185120222103265129","url":null,"abstract":"ABSTRACT Spinal cord injuries can have serious consequences for the individual, such as loss of motor function, sensory impairment, and alteration of physiological systems functions. Treatments for spinal cord injuries involve the use of drugs and surgical approaches. In the surgical field, there is a question about the ideal time after the trauma to perform the surgical procedure. The studies divide the time until surgery after the injury into two categories: “early” and “late”. To review the scientific literature on this topic, and to assess the relative effectiveness of early versus late decompressive surgery, we considered early intervention up to 24 hours and late intervention from 24 hours after the injury. For this, we performed a literature review and selected retrospective, prospective observational studies, clinical studies, and reviews with meta-analysis that compared the recovery time of patients with spinal cord injury after surgeries performed within 24 hours (early) and after 24 hours (late). The results showed potential for neurological improvement with early or even ultra-early surgical decompression (up to 12 hours) in patients with traumatic cervical spinal cord injury. On the other hand, reports about the advantage of early decompression when there is a thoracic injury are scarce. In addition to the time to decompression, the concomitant use of some drugs seems to play an important role in patients’ recovery. Level of Evidence II; Literature review.","PeriodicalId":40025,"journal":{"name":"Coluna/ Columna","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67479961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
期刊
Coluna/ Columna
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1