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Primary Cementless Total Hip Arthroplasty with a Sandwich Type in Ceramic-Ceramic Articulation (Minimum 10-Year Follow up Results) 夹层型陶瓷-陶瓷关节一期无骨水泥全髋关节置换术(至少10年随访结果)
Pub Date : 2011-09-01 DOI: 10.5371/JKHS.2011.23.3.206
U. Yoon, H. Min, J. Seo, Jinsoo Kim, B. Lim, Joon Yub Kim, Hyun Seok Oh, J. Seok, S. Y. Baek
인공관절 전치환술시 폴리에틸렌의 마모와 마모된 입자 에 의한 체내 면역계의 생물학적 반응은 골용해와 삽입물 의 해리를 가져와 인공관절의 수명에 주요한 영향을 미치 게 된다. 이러한 문제들을 줄이기 위한 노력으로 시도된 세라믹-세라믹 관절면은 높은 탄성계수와 경도를 가지며, 마찰계수가 생체 관절면에 비슷하고 생체와는 거의 반응 하지 않는 특성을 가지고 있다. 1971년 프랑스의 Pierre Boutin이 알루미나 세라믹을 관절면에 이용한 것이 시 초라 할 수 있으며 초기의 세라믹은 약한 비구 고정력에 의한 비구컵의 해리, 낮은 순도와 큰 입자크기 때문에 발 생하는 세라믹의 파괴가 많아 사용에 제한이 있었으나, 최근 제조 공정의 발전으로 매우 작은 미세입자 크기가 가 능해짐에 따라 고순도와 고밀도에 의한 경도(hardness), 강도(strength)와 같은 기계적 특성이 우수해졌으며 비구 컵에 금속 shell를 적용하고 골두와 티타늄 대퇴 삽입물간 에 Morse-taper 잠금장치를 도입하여 고정력을 향상시키 게 되었다. 하지만 세라믹은 경도와 마모특성은 우수한 반면 취성(brittleness)이 강하여 부품의 파손 가능성이 높 다. 이에 저자들은 세라믹-세라믹 관절면의 단점인 취성 을 감소시키기 위해 고안된 세라믹 라이너에 폴리에틸렌 을 부착시킨 샌드위치형 세라믹-세라믹 관절면을 이용한 Submitted: April 25, 2011 1st revision: June 30, 2011 2nd revision: August 18, 2011 3rd revision: August 22, 2011 4rd revision: September 7, 2011 Final acceptance: September 14, 2011
人工关节前置置换手术时,聚乙烯的磨损和因磨损粒子引起的体内免疫系统的生物学反应,会导致骨溶解和插入物的解离,对人工关节的寿命产生主要影响。为了减少这些问题而尝试的陶瓷-陶瓷关节面具有较高的弹性系数和硬度,摩擦系数与生物关节面相似,具有与生物几乎没有反应的特性。1971年法国的Pierre Boutin将铝或陶瓷利用在关节面可能是寒酸的陶瓷,早期的陶瓷是由较弱的比丘固定力引起的比丘杯的解解,由于纯度低和粒子大而产生的陶瓷破坏较多,使用受到限制;最近制造工程的发展,很善于做小微粒子大小随着高纯度和高密度的硬度(hardness)、强度(strength)和同样的机械特性变得优秀,比丘杯子适用金属shell,两个进球和钛插入大腿之间莫尔斯- taper水要引入锁定装置固定力,提高了。但是陶瓷的硬度和磨损特性都很优秀,而脆性(brittleness)较强,因此配件的破损可能性较高。作者将聚乙烯附在陶瓷衬垫上,用于减少陶瓷关节的缺点。Submitted: April 25, 2011 1st revision: June 30, 2011 2nd revision: August 18, 2011 3rd revision:August 22, 2011 4rd revision: September 7, 2011 Final acceptance: September 14, 2011
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引用次数: 1
The Results of Cementless Total Hip Arthroplasty for Primary Osteoarthritis Compared with Avascular Necrosis of the Femoral Head 无骨水泥全髋关节置换术治疗原发性骨关节炎与股骨头缺血性坏死的疗效比较
Pub Date : 2011-09-01 DOI: 10.5371/JKHS.2011.23.3.192
J. O. Kim, B. Park, Hong-Man Cho, Ju Han Kim
Purpose: Cementless total hip arthroplasty was performed to treat primary osteoarthritis of the hip and avascular necrosis of the femoral head. The clinical and radiological results of the acetabular cups and femoral stems were compared. Materials and Methods: The subjects were 84 cases who underwent primary cementless total hip arthroplasty from March 1992 to May 2001. The 84 cases were followed up for at least eight years. The patients were divided into the following two groups: group (A), 38 cases of degenerative osteoarthritis of the hip; and group (B), 46 cases of avascular necrosis of the hip. The clinical evaluation was conducted based on the Harris Hip Score (HHS). A radiological assessment was performed to determine if osteolysis or acetabular loosening had occurred. The results were analyzed statistically. Results: The postoperative HHS of groups A and B at the final follow-up were 92.1 and 91.2, respectively (p=0.483). The radiological results revealed 9 and 15 cases of acetabular osteolysis (p=0.671) and 1 and 3 cases of vertical migration of the acetabular cups in the group A and B, respectively. Eight and 7 complications (p=0.572) were encountered in group A and B, respectively. Among these, 4 and 5 cases of revisional total hip arthroplasty were performed in group A and B, respectively. The results of survival analysis were similar in the two groups (p=0.969). Conclusion: The clinical and radiological features of the acetabular cups and stems were similar in the two groups. Nevertheless, further studies will be needed due to the high rate of polyethylene liner wear and osteolysis around the acetabular cups or femoral stems.
目的:采用无骨水泥全髋关节置换术治疗原发性髋关节骨性关节炎和股骨头缺血性坏死。比较髋臼杯和股骨干的临床和影像学结果。材料与方法:选取1992年3月至2001年5月行一期无骨水泥全髋关节置换术的84例患者为研究对象。对84例患者进行了至少8年的随访。将患者分为两组:A组,退行性髋关节骨性关节炎38例;B组46例髋关节缺血性坏死。临床评价依据Harris髋关节评分(HHS)。放射学评估确定是否发生骨溶解或髋臼松动。结果进行统计学分析。结果:A组术后HHS为92.1,B组术后HHS为91.2 (p=0.483)。影像学结果显示,A组髋臼骨溶解9例,B组髋臼杯垂直移位1例,B组髋臼杯垂直移位15例(p=0.671)。A组8例,B组7例(p=0.572)。其中,A组4例,B组5例,行翻修全髋关节置换术。两组患者生存分析结果相似(p=0.969)。结论:两组患者髋臼杯和髋臼柄的临床和影像学特征相似。然而,由于髋臼杯或股干周围聚乙烯衬垫磨损和骨溶解率高,需要进一步的研究。
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引用次数: 1
Traumatic Disassembly of a Bipolar Hip Prosthesis - A Case Report - 双相髋关节假体外伤性拆卸一例报告
Pub Date : 2011-06-01 DOI: 10.5371/JKHS.2011.23.2.151
B. Park, Ju-Oh Kim, Hong-Man Cho, J. Sim
We report a rare case of a complete disassembly of the inner head from the bipolar cup without polyethylene wear and locking system failure. An 84-year-old man who had a femur neck fracture of the right hip underwent a replacement of the bipolar prosthesis 4 months ago. He fell down from a height of a chair and felt a sudden sharp pain in the right hip. Roentgenograms revealed that the inner head was dislocated from the outer cup; subsequently, a revision surgery was carried out. When the outer head was removed from the acetabulum, the bearing insert and locking ring were not deformed. Because there was no evidence of loosening of the femoral stem, identicallysized bipolar cup and metal head replacement was performed. At a 6 months follow-up, he had mild hip pain but had returned fully to daily living.
我们报告一个罕见的情况下完全拆卸内头从双极杯没有聚乙烯磨损和锁定系统故障。一位84岁男性右髋关节股骨颈骨折4个月前接受了双极假体置换手术。他从椅子上摔了下来,右臀部突然感到一阵剧痛。x线摄影显示内头与外杯脱位;随后,进行了翻修手术。当外头从髋臼取出时,轴承内嵌件和锁紧环没有变形。由于没有证据表明股骨干松动,因此进行了相同尺寸的双极杯和金属头置换术。在6个月的随访中,他有轻微的髋关节疼痛,但已经完全恢复日常生活。
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引用次数: 0
Anterior Approaches in Hip Surgery 髋关节手术中的前路入路
Pub Date : 2011-06-01 DOI: 10.5371/JKHS.2011.23.2.95
Tae-Young Kim, Seung-Hwan Cha, O. Maidar, S. S. Lee
The Smith-Petersen anterior approach and the Watson-Jones anterolateral approach are the two most renowned anterior approaches for hip surgery. The anterior approach offers several advantages, including a reduced dislocation risk as compared with that associated with the posterior approach. The post-operative dislocation rate after total hip arthroplasty is known to be 2~3 times lower than that of the posterior approach. However, a more extensive skin incision and poor anatomical visualization are some of the disadvantages of the anterior approach. Nevertheless, since this approach preserves the circulation to the femoral head, the ability to perform the anterior approach is imperative for hip surgeons.
Smith-Petersen前路和Watson-Jones前外侧入路是髋关节手术中最著名的两种前路。前路入路有几个优点,包括与后路入路相比脱位风险降低。全髋关节置换术后脱位率比后路低2~3倍。然而,更广泛的皮肤切口和较差的解剖可视化是前路手术的一些缺点。然而,由于这种入路保留了股骨头的循环,因此对髋关节外科医生来说,进行前路入路是必要的。
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引用次数: 0
Do You Need CAOS (Computer Assisted Orthopedic Surgery) in THA? - From a Negative Perspective - 髋关节置换术是否需要计算机辅助骨科手术(CAOS) ?-从消极的角度看-
Pub Date : 2011-06-01 DOI: 10.5371/JKHS.2011.23.2.103
Joo Yup Lee, Joo-Hyoun Song, C. Kim
최근 인공 고관절에 사용되는 기구와 수술 술기는 우수 한 통증 감소와, 거의 정상에 가까운 기능 회복을 얻을 수 있도록 하기에, 의학 분야에서 매우 우수한 수술 중의 하 나로 자리매김 하였다. 이전에 비해 인공 관절의 재료, 고정 방법 그리고 관절면의 개선이 뚜렷하여 젊고 활동적 인 환자에서도 인공 고관절 치환이 가능해졌으며, 나아가 더욱 작은 절개와 적은 연부조직 손상으로 조기 기능회복 을 얻기 위해 노력하고 있다. 인공 고관절의 또 다른 개발 분야로서, 기구 삽입의 정확도를 높이기 위한, 소위 ‘CAOS (Computer Assisted Orthopedic Surgery)’가 도입 되고 있다. CAOS를 옹호하는 학자들은 이를 이용하 여 인공 고관절 치환술을 시행하면 기구 삽입의 정확도와 일관성을 향상시켜, 부정확한 기구 삽입으로 인한 탈구의 위험, 조기 관절면의 마모 그리고 충돌 등을 줄일 수 있고, 다리 길이와 오프셋의 조절이 용이 하다고 주장 한다. 컴퓨터를 이용하는 인공 고관절 전치환술은 수술 전 전 산화단층 촬영을 이용하는 CT-based navigation, 수술 중 영상증폭장치를 이용하는 intraoperative fluoroscopy navigation 그리고 해부학적 landmark를 이용하는 imageless navigation, 세 가지로 나누어 진다. 이 세 가지 방법들을 이용한 인공 고관절 전치환술의 결과가 우수한다는 많은 보고가 있으나 CAOS의 장점뿐만 이 아니라 단점과 한계를 알아보고 개선 방향을 연구하여, 인공고관절의 치료 성적을 극대화시키는 것이 필요하다.
最近人工骨关节使用的器具和手术术器能够得到良好的疼痛减轻,接近正常的功能恢复,在医学领域成为非常优秀的手术之一。与以前相比,人工关节的材料、固定方法以及关节面的改善非常明显,年轻活跃的患者也可以进行人工髋关节置换,进而通过更小的切开和较少的软骨组织损伤,努力获得早期功能恢复。作为人工髋关节的另一个发展领域,正在引入所谓的CAOS (Computer Assisted Orthopedic Surgery),以提高仪器插入的准确度。拥护caos学者们使用该多人工关节置换,机构要执行插入的酒,提高准确度和一贯性,因不正确的机构插入脱臼的危险,早期관절면的磨损以及可以减少冲突等,容易调节腿长度和胶版的主张。利用电脑的人工骨关节前置置换手术分为手术前利用前氧化断层摄影的CT-based navigation、手术中利用影像增幅装置的intraoperative fluoroscopy navigation、利用解剖学landmark的imageless navigation三种。虽然有很多报告称利用这三种方法的人工骨关节前置手术结果非常优秀,但是不仅要了解CAOS的优点,还要了解其缺点和局限性,研究改善方向,最大限度地提高人工骨关节的治疗成绩。
{"title":"Do You Need CAOS (Computer Assisted Orthopedic Surgery) in THA? - From a Negative Perspective -","authors":"Joo Yup Lee, Joo-Hyoun Song, C. Kim","doi":"10.5371/JKHS.2011.23.2.103","DOIUrl":"https://doi.org/10.5371/JKHS.2011.23.2.103","url":null,"abstract":"최근 인공 고관절에 사용되는 기구와 수술 술기는 우수 한 통증 감소와, 거의 정상에 가까운 기능 회복을 얻을 수 있도록 하기에, 의학 분야에서 매우 우수한 수술 중의 하 나로 자리매김 하였다. 이전에 비해 인공 관절의 재료, 고정 방법 그리고 관절면의 개선이 뚜렷하여 젊고 활동적 인 환자에서도 인공 고관절 치환이 가능해졌으며, 나아가 더욱 작은 절개와 적은 연부조직 손상으로 조기 기능회복 을 얻기 위해 노력하고 있다. 인공 고관절의 또 다른 개발 분야로서, 기구 삽입의 정확도를 높이기 위한, 소위 ‘CAOS (Computer Assisted Orthopedic Surgery)’가 도입 되고 있다. CAOS를 옹호하는 학자들은 이를 이용하 여 인공 고관절 치환술을 시행하면 기구 삽입의 정확도와 일관성을 향상시켜, 부정확한 기구 삽입으로 인한 탈구의 위험, 조기 관절면의 마모 그리고 충돌 등을 줄일 수 있고, 다리 길이와 오프셋의 조절이 용이 하다고 주장 한다. 컴퓨터를 이용하는 인공 고관절 전치환술은 수술 전 전 산화단층 촬영을 이용하는 CT-based navigation, 수술 중 영상증폭장치를 이용하는 intraoperative fluoroscopy navigation 그리고 해부학적 landmark를 이용하는 imageless navigation, 세 가지로 나누어 진다. 이 세 가지 방법들을 이용한 인공 고관절 전치환술의 결과가 우수한다는 많은 보고가 있으나 CAOS의 장점뿐만 이 아니라 단점과 한계를 알아보고 개선 방향을 연구하여, 인공고관절의 치료 성적을 극대화시키는 것이 필요하다.","PeriodicalId":410202,"journal":{"name":"The Journal of the Korean Hip Society","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129559031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Reliability of the Radiologic Measurement Methods for Assessment of Osteoporosis Using the Digital Hip Radiograph 使用数字髋关节x线片评估骨质疏松的放射学测量方法的可靠性
Pub Date : 2011-06-01 DOI: 10.5371/JKHS.2011.23.2.142
H. Yun, J. Yi, Deuk-Soo Lim, Sung Chul Park, Seongrok Oh
Purpose: We evaluated the usefulness of radiographic parameters for osteoporosis by analyzing the results of radiographic parameters determined by digital hip radiographs and bone mineral density T-scores, as assessed by Dual Energy X-ray Absorptiometry (DEXA). Materials and Methods: The authors reviewed 100 subjects in the hip fracture group and 50 in the non-fracture control group. Digital hip radiographs were assessed to determine the values of Singh index, Canal-to-Calcar Ratio, and Cortical Thickness Index (CTI). Bone mineral density was assessed by DEXA. Results: Intraclass Correlation Coefficient (ICC) results of the CTI were above 0.8 in the fracture group. Compared to the control group, the fracture group showed higher ICCs. Interobserver ICCs were especially lower in the control group. There were statistically significant correlations between CTI and DEXA (r=0.50~0.58, p<0.05). In the analysis of ROC curves, a mean threshold for CTI set a value of 0.54 (0.53~0.55), and mean sensitivity and specificity were 75.5% (69~79%) and 67.8% (65~78%), respectively. Conclusion: CTI showed reasonable reliability and correlation with DEXA results. CTI was a useful radiographic parameter to alert the surgeon to recommend referral for osteoporosis evaluation in elderly hip fracture patients.
目的:我们通过分析数字髋关节x线片和骨密度t评分(双能x线吸收仪(DEXA)评估)确定的x线片参数的结果,评估放射参数对骨质疏松症的有用性。材料与方法:回顾性分析髋部骨折组100例,非骨折对照组50例。评估数字髋关节x线片以确定Singh指数、Canal-to-Calcar比值和皮质厚度指数(CTI)的值。DEXA测定骨密度。结果:骨折组CTI的类内相关系数(ICC)均在0.8以上。骨折组的ICCs高于对照组。观察者间ICCs在对照组尤其低。CTI与DEXA的相关性有统计学意义(r=0.50~0.58, p<0.05)。在ROC曲线分析中,CTI的平均阈值为0.54(0.53~0.55),平均敏感性和特异性分别为75.5%(69~79%)和67.8%(65~78%)。结论:CTI与DEXA结果具有合理的信度和相关性。CTI是一个有用的影像学参数,提醒外科医生推荐老年髋部骨折患者骨质疏松评估转诊。
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引用次数: 7
Ceramic on Ceramic Total Hip Arthroplasty - The Results of a Minimum 10-Years Follow up - 陶瓷对陶瓷全髋关节置换术-至少10年随访的结果
Pub Date : 2011-06-01 DOI: 10.5371/JKHS.2011.23.2.116
D. Moon, J. Choi, Dong Whan Kim, Kwang Hee Kim
Purpose: We wanted to evaluate the clinical and radiographic results of ceramic on ceramic bearing cementless total hip arthroplasty with a minimum of 10-years follow up. Materials and Methods: This study was performed on 44 patients and 51 hips, and the patients were recruited among the patients who underwent ceramic-ceramic type cementless total hip arthroplasty from August 1998 to February 2000 and they were available for 10-years or longer follow up. The gender ratio was 28 males and 16 females, and the mean age at the time of surgery was 49 years (range: 26~77 years). Regarding the causality of disease, osteonecrosis was noted in 36 cases, degenerative arthritis was noted in 4 cases, acetabular dysplasia was noted in 4 cases and septic or tuberculous hip sequelae was noted in 7 cases. The clinical evaluation was performed according to the Harris hip score, and for the radiological evaluation of the femoral component, we assessed the degree of subsidence and the presence of periprosthetic osteolysis, endosteal new bone formation and cortical hypertrophy, and the final fixation state of the implant. In the cases with an acetabular cup osteoscleostic line in the vicinity of the acetabular cup, endosteal new bone formation, acetabular osteolysis and the vertical migration as well as the horizontal migration of the acetubular cup were assessed. Results: Regarding the clinical outcomes, the Harris hip score was improved from an average 59 points to 93 points at the final follow up. For the radiological results, osteolysis was not detected in the acetabular and femoral components, the subsidence of femoral stem was not beyond 2 mm on average and significant subsidence was not detected. In regard to complications, linear fracture during surgery was noted in 6 cases and postoperative hip dislocation was noted in 1 case. A ceramic head fracture occurred in one case and a ceramic liner fracture occurred in 2 cases. Conclusion: This type of articulation is a promising option at a minimum of 10-years follow up of 51 hips that underwent ceramic-ceramic bearing cementless total hip arthroplasty. However, our results demonstrated that surgeons should be aware of the potential risks of ceramic fracture when using ceramic-on-ceramic bearing surfaces. Additional longer-term follow-up is necessary.
目的:我们希望通过至少10年的随访来评估陶瓷对陶瓷轴承无骨水泥全髋关节置换术的临床和影像学结果。材料与方法:本研究纳入1998年8月至2000年2月行陶瓷-陶瓷型无骨水泥全髋关节置换术的患者44例,51髋,随访10年以上。性别比例:男性28例,女性16例,手术时平均年龄49岁(范围:26~77岁)。病因方面,骨坏死36例,退行性关节炎4例,髋臼发育不良4例,脓毒性或结核性髋关节后遗症7例。根据Harris髋关节评分进行临床评估,对于股骨假体的放射学评估,我们评估了下沉程度和假体周围骨溶解的存在,骨内新生骨形成和皮质肥大,以及假体的最终固定状态。在髋臼杯附近有骨硬化线的病例中,评估骨内新生骨形成、髋臼骨溶解以及髋臼杯的垂直移动和水平移动。结果:临床结果方面,Harris髋关节评分由平均59分提高到最后随访时的93分。放射学结果显示,在髋臼和股骨部件中未检测到骨溶解,股骨干下沉平均不超过2mm,未检测到明显的下沉。并发症方面,术中线状骨折6例,术后髋关节脱位1例。陶瓷头部骨折1例,陶瓷内胆骨折2例。结论:在51例髋关节接受陶瓷-陶瓷轴承无水泥全髋关节置换术至少10年的随访中,这种类型的关节是一个有希望的选择。然而,我们的研究结果表明,外科医生在使用陶瓷对陶瓷承载表面时应该意识到陶瓷骨折的潜在风险。额外的长期随访是必要的。
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引用次数: 1
Subtrochanteric Femur Fracture after Multiple Drilling for Treatment of Nontraumatic Osteonecrosis of the Femoral Head - A Case Report - 多次钻孔治疗股骨头非外伤性骨坏死后股骨转子下骨折1例报告
Pub Date : 2011-06-01 DOI: 10.5371/JKHS.2011.23.2.155
Jong Won Kim, Hyun-Soo Park, J. Rha, Young-Soo Jang, J. Jung, Jin-Phil Yang, Jae-Hyuk Choi
Multiple drilling of the femoral head is a commonly-used surgical technique for the treatment of osteonecrosis. Several holes are drilled into the femoral head using a small-diameter Steinmann pin. This decompression technique promotes revascularization and regeneration of necrotic tissue in the femoral head. Known complications are heterotopic ossification and femoral subtrochanteric fractures, although these have only been rarely reported. Our case study focuses on a subtrochanteric fracture 6 weeks after a multiple drilling operation.
股骨头多次钻孔是治疗骨坏死的常用手术技术。用小直径斯坦曼针在股骨头上钻几个孔。这种减压技术可促进股骨头坏死组织的血运重建和再生。已知的并发症是异位骨化和股骨粗隆下骨折,尽管这些报道很少。我们的病例研究集中在多次钻孔手术后6周的转子下骨折。
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引用次数: 1
Immature Heterotopic Ossification in the Iliacus Muscle in Spinal Cord Injury - A Case Report - 脊髓损伤后髂肌未成熟异位骨化1例报告
Pub Date : 2011-06-01 DOI: 10.5371/JKHS.2011.23.2.161
Jong Seok Park, J. Kim, W. Kim, Sang-Wook Choi, S. Cho, Byung-Woong Jang
Heterotopic ossification (HO) is a frequent complication associated with spinal cord injury and can lead to significant problems during rehabilitation. Surgical resection of HO could be applied to patients who do not respond to conservative treatment. To reduce the risk of recurrence after the operation, radiation therapy and NSAID or bisphosphonate administration may be utilized. We report the case of a 48-year-old male with a T3-sparing spinal cord injury who underwent successful treatment of immature HO in the iliacus muscle with a combination of surgical resection, radiation therapy, and NSAID administration.
异位骨化(HO)是与脊髓损伤相关的常见并发症,可导致康复过程中的重大问题。手术切除HO可应用于保守治疗无效的患者。为了减少手术后复发的风险,可以使用放疗和非甾体抗炎药或双膦酸盐。我们报告一例48岁男性t3保留脊髓损伤患者,通过手术切除、放射治疗和非甾体抗炎药联合成功治疗髂肌未成熟HO。
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引用次数: 0
Diagnosis of Osteoporosis 骨质疏松症的诊断
Pub Date : 2011-06-01 DOI: 10.5371/JKHS.2011.23.2.108
J. Kim, Young Wan Moon
Osteoporosis is defined as a skeletal disorder characterized by compromised bone strength, predisposing an individual to increased fracture risk. Many factors can lead to the development of osteoporosis. It is usually asymptomatic unless osteoporotic fracture and secondary changes of bone structure occur. Early radiographs show normal findings; however, osteopenic appearance, fracture, cortical bone thinning, and roughening of bone trabeculae can be found according to severity of osteoporosis. These symptoms are most frequently found in the spine and proximal femur. Bone mineral density (BMD) is the standard method used to diagnose osteoporosis, and dual energy X-ray absorptiometry (DXA), one of the measurement tools for BMD, is particularly regarded as the appropriate tool applicable to WHO criteria, which defines osteoporosis as a T-score of less than 2.5 SDs below the mean of young adult women. Peripheral densitometry is less useful in predicting the risk of fractures of the spine and proximal femur, and it is not enough to diagnose and treat osteoporosis. Biochemical bone markers have demonstrated utility in clinical research and trials; however, they cannot replace BMD as a diagnostic tool. WHO recently developed FRAX, a novel method we can use to more conveniently evaluate osteoporotic fracture risk.
骨质疏松症是一种骨骼疾病,其特征是骨骼强度降低,易导致个体骨折风险增加。许多因素可导致骨质疏松症的发展。除非发生骨质疏松性骨折和继发性骨结构改变,否则通常无症状。早期x线片显示正常;然而,根据骨质疏松的严重程度,可以发现骨质减少、骨折、皮质骨变薄、骨小梁变粗。这些症状最常见于脊柱和股骨近端。骨密度(BMD)是诊断骨质疏松症的标准方法,双能x线骨密度测量仪(DXA)是骨密度测量工具之一,尤其被认为是适用于WHO标准的合适工具。WHO标准将骨质疏松症定义为年轻成年女性的t评分低于平均值2.5个标准差。外周密度测定在预测脊柱和股骨近端骨折风险方面用处不大,也不足以诊断和治疗骨质疏松症。骨生化标记物已在临床研究和试验中得到证实;然而,它们不能取代BMD作为诊断工具。世卫组织最近开发了FRAX,这是一种我们可以更方便地评估骨质疏松性骨折风险的新方法。
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引用次数: 6
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The Journal of the Korean Hip Society
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