S. Wijaya, Yuki Tanaka, M. Altaf-Ul-Amin, Aki Morita, F. Afendi, I. Batubara, N. Ono, L. K. Darusman, S. Kanaya
Recently, the use of traditional medicines for medical treatment and maintaining good health is increasing. This condition has been followed by the increasing number of research activities, publications and databases of crude drug systems to support the scientific aspects of traditional medicines. Nevertheless, the information about traditional medicines is scattered in an unorganized manner and the existing traditional medicine databases have been stored by different database schemas. Therefore, a standardized tool that integrates and provides information about various herbal medicines is needed. In this study, we developed a mobile application with Waterfall Method, called as Herbal Medicine Systems, for various kinds of crude drug systems as a reference of traditional medicines. The KNApSAcK Family Databases were used as a role model to design the database schemas of crude drug systems by using data warehouse pre-processing technique. The Herbal Medicine Systems application is preloaded with 336 and 5,310 Kampo and Jamu formulas respectively from the KNApSAcK Kampo and KNApSAcK Jamu databases. In addition, the Herbal Medicine Systems can predict the efficacy of crude drug combinations by using Random Forest classifier developed based on the formulation of Indonesian Jamu with the average accuracy of 90%.
{"title":"Utilization of KNApSAcK Family Databases for Developing Herbal Medicine Systems","authors":"S. Wijaya, Yuki Tanaka, M. Altaf-Ul-Amin, Aki Morita, F. Afendi, I. Batubara, N. Ono, L. K. Darusman, S. Kanaya","doi":"10.2751/JCAC.17.1","DOIUrl":"https://doi.org/10.2751/JCAC.17.1","url":null,"abstract":"Recently, the use of traditional medicines for medical treatment and maintaining good health is increasing. This condition has been followed by the increasing number of research activities, publications and databases of crude drug systems to support the scientific aspects of traditional medicines. Nevertheless, the information about traditional medicines is scattered in an unorganized manner and the existing traditional medicine databases have been stored by different database schemas. Therefore, a standardized tool that integrates and provides information about various herbal medicines is needed. In this study, we developed a mobile application with Waterfall Method, called as Herbal Medicine Systems, for various kinds of crude drug systems as a reference of traditional medicines. The KNApSAcK Family Databases were used as a role model to design the database schemas of crude drug systems by using data warehouse pre-processing technique. The Herbal Medicine Systems application is preloaded with 336 and 5,310 Kampo and Jamu formulas respectively from the KNApSAcK Kampo and KNApSAcK Jamu databases. In addition, the Herbal Medicine Systems can predict the efficacy of crude drug combinations by using Random Forest classifier developed based on the formulation of Indonesian Jamu with the average accuracy of 90%.","PeriodicalId":41457,"journal":{"name":"Journal of Computer Aided Chemistry","volume":"20 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2751/JCAC.17.1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69255119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kenichi Tanaka, H. Kaneko, Kyosuke Nagasaka, K. Funatsu
{"title":"Improvement of Prediction Accuracy in Just-In-Time Modelling Using Distance-based Database Update","authors":"Kenichi Tanaka, H. Kaneko, Kyosuke Nagasaka, K. Funatsu","doi":"10.2751/JCAC.16.1","DOIUrl":"https://doi.org/10.2751/JCAC.16.1","url":null,"abstract":"","PeriodicalId":41457,"journal":{"name":"Journal of Computer Aided Chemistry","volume":"16 1","pages":"1-14"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2751/JCAC.16.1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69255064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Kawashita, Hiroyuki Yamasaki, Tomoyuki Miyao, Kentaro Kawai, Y. Sakae, Takeshi Ishikawa, K. Mori, Shinya Nakamura, H. Kaneko
{"title":"A Mini-review on Chemoinformatics Approaches for Drug Discovery","authors":"N. Kawashita, Hiroyuki Yamasaki, Tomoyuki Miyao, Kentaro Kawai, Y. Sakae, Takeshi Ishikawa, K. Mori, Shinya Nakamura, H. Kaneko","doi":"10.2751/JCAC.16.15","DOIUrl":"https://doi.org/10.2751/JCAC.16.15","url":null,"abstract":"","PeriodicalId":41457,"journal":{"name":"Journal of Computer Aided Chemistry","volume":"16 1","pages":"15-29"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2751/JCAC.16.15","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69255100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Development of a New Regression Method Considering Predictability and Molecular Design of Amine Compounds for CO2 Separation and Recovery","authors":"K. Mishima, H. Kaneko, K. Funatsu","doi":"10.2751/JCAC.14.1","DOIUrl":"https://doi.org/10.2751/JCAC.14.1","url":null,"abstract":"","PeriodicalId":41457,"journal":{"name":"Journal of Computer Aided Chemistry","volume":"14 1","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69254969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Erd^|^#337;s Numbers of Japanese Informational Chemists","authors":"A. Oda","doi":"10.2751/JCAC.14.36","DOIUrl":"https://doi.org/10.2751/JCAC.14.36","url":null,"abstract":"","PeriodicalId":41457,"journal":{"name":"Journal of Computer Aided Chemistry","volume":"14 1","pages":"36-43"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69255037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Development of a New Index to Monitor Database for Soft Sensors","authors":"H. Kaneko, K. Funatsu","doi":"10.2751/JCAC.14.11","DOIUrl":"https://doi.org/10.2751/JCAC.14.11","url":null,"abstract":"","PeriodicalId":41457,"journal":{"name":"Journal of Computer Aided Chemistry","volume":"58 1","pages":"11-22"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2751/JCAC.14.11","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69254981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}