Pub Date : 2023-10-31DOI: 10.14730/aaps.2023.00941
Yunsung Park, Hyeokjae Kwon, Sunje Kim, Seung Han Song, Sang-Ha Oh, Yooseok Ha
Congenital melanocytic nevus (CMN) is a benign condition that either is present at birth or develops in the first weeks of life. Surgical removal is typically performed to improve cosmetic appearance and reduce the risk of malignant transformation. In this report, we present the case of a 26-year-old woman with a medium-sized CMN on her left breast. The nevus measured 14×8 cm, and the patient desired a single-stage excision. However, this approach would result in a large skin defect that would be challenging to reconstruct using a local flap or skin graft. Moreover, it could potentially compromise the maintenance of natural sagging and the contour of the breast. Consequently, we opted to place a thin thoracodorsal artery perforator free flap following the removal of the CMN. The patient was satisfied with the overall surgical results. By utilizing this free flap for reconstruction, we successfully preserved the natural shape and contour of the breast without complications such as postoperative hypertrophic scarring or contracture at the recipient site.
{"title":"Reconstruction of a medium-sized congenital melanocytic nevus defect using a thin thoracodorsal artery perforator free flap: a case report","authors":"Yunsung Park, Hyeokjae Kwon, Sunje Kim, Seung Han Song, Sang-Ha Oh, Yooseok Ha","doi":"10.14730/aaps.2023.00941","DOIUrl":"https://doi.org/10.14730/aaps.2023.00941","url":null,"abstract":"Congenital melanocytic nevus (CMN) is a benign condition that either is present at birth or develops in the first weeks of life. Surgical removal is typically performed to improve cosmetic appearance and reduce the risk of malignant transformation. In this report, we present the case of a 26-year-old woman with a medium-sized CMN on her left breast. The nevus measured 14×8 cm, and the patient desired a single-stage excision. However, this approach would result in a large skin defect that would be challenging to reconstruct using a local flap or skin graft. Moreover, it could potentially compromise the maintenance of natural sagging and the contour of the breast. Consequently, we opted to place a thin thoracodorsal artery perforator free flap following the removal of the CMN. The patient was satisfied with the overall surgical results. By utilizing this free flap for reconstruction, we successfully preserved the natural shape and contour of the breast without complications such as postoperative hypertrophic scarring or contracture at the recipient site.","PeriodicalId":41514,"journal":{"name":"Archives of Aesthetic Plastic Surgery","volume":"127 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135871795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-31DOI: 10.14730/aaps.2023.00948
Young Jun Kim, Ji Seon Cheon, Min Hyub Choi, Woo Young Choi
The cheek, a highly visible and significant aspect of an individual’s appearance, is situated adjacent to several structures involved in facial expressions, including the eye, mouth, and surrounding facial muscles. Consequently, aesthetic reconstruction for large cutaneous defects of the cheek remains a challenge for plastic surgeons. We experienced a case of an 83-year-old woman with a large (7×10 cm) facial defect following the removal of squamous cell carcinoma. We elevated a cervicofacial skin flap containing the superficial layer of the superficial musculoaponeurotic system and a blood supply via the dermal plexus in a random pattern. Through this method, we achieved aesthetically favorable reconstruction of a large facial defect using a cervicofacial transposition skin flap. By avoiding extensive dissection, we achieved adequate coverage for even a quite sizable facial defect, with a short recovery time. This method prevented facial nerve injury and made it possible to simultaneously obtain an aesthetically favorable outcome.
{"title":"Modified cervicofacial transposition flap: a case report of aesthetic considerations after resection of a huge facial squamous cell carcinoma","authors":"Young Jun Kim, Ji Seon Cheon, Min Hyub Choi, Woo Young Choi","doi":"10.14730/aaps.2023.00948","DOIUrl":"https://doi.org/10.14730/aaps.2023.00948","url":null,"abstract":"The cheek, a highly visible and significant aspect of an individual’s appearance, is situated adjacent to several structures involved in facial expressions, including the eye, mouth, and surrounding facial muscles. Consequently, aesthetic reconstruction for large cutaneous defects of the cheek remains a challenge for plastic surgeons. We experienced a case of an 83-year-old woman with a large (7×10 cm) facial defect following the removal of squamous cell carcinoma. We elevated a cervicofacial skin flap containing the superficial layer of the superficial musculoaponeurotic system and a blood supply via the dermal plexus in a random pattern. Through this method, we achieved aesthetically favorable reconstruction of a large facial defect using a cervicofacial transposition skin flap. By avoiding extensive dissection, we achieved adequate coverage for even a quite sizable facial defect, with a short recovery time. This method prevented facial nerve injury and made it possible to simultaneously obtain an aesthetically favorable outcome.","PeriodicalId":41514,"journal":{"name":"Archives of Aesthetic Plastic Surgery","volume":"8 8","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135808381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-31DOI: 10.14730/aaps.2022.00787
Eun Chan Kim, Hyun Gyo Jeong, S. Wee
Scars are still a challenging problem in medical practice, despite advancements in treatment modalities. Numerous treatment modalities, ranging from simple revision, Z-plasty, and W-plasty to laser treatments, have been used to treat scar deformities. However, for wide depressed scars, additional methods are needed to completely restore the contour of the depression caused by tissue adhesion. We report on the case of a 34-year-old woman with a wide depressed scar deformity on the left upper buttock and the encouraging results of an autologous fat graft injection technique that utilized a cutting wire to form a pocket for the fat graft site, while simultaneously resolving the adhesion caused by the tissue. This method is safe and easily reproducible, making it a useful addition to the surgeon’s toolkit when dealing with such lesions.
{"title":"A wide depressed scar deformity treated with cutting wire and autologous fat graft: a case report","authors":"Eun Chan Kim, Hyun Gyo Jeong, S. Wee","doi":"10.14730/aaps.2022.00787","DOIUrl":"https://doi.org/10.14730/aaps.2022.00787","url":null,"abstract":"Scars are still a challenging problem in medical practice, despite advancements in treatment modalities. Numerous treatment modalities, ranging from simple revision, Z-plasty, and W-plasty to laser treatments, have been used to treat scar deformities. However, for wide depressed scars, additional methods are needed to completely restore the contour of the depression caused by tissue adhesion. We report on the case of a 34-year-old woman with a wide depressed scar deformity on the left upper buttock and the encouraging results of an autologous fat graft injection technique that utilized a cutting wire to form a pocket for the fat graft site, while simultaneously resolving the adhesion caused by the tissue. This method is safe and easily reproducible, making it a useful addition to the surgeon’s toolkit when dealing with such lesions.","PeriodicalId":41514,"journal":{"name":"Archives of Aesthetic Plastic Surgery","volume":"47 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67139346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-31DOI: 10.14730/aaps.2023.00843
Y. Choi, Jeong-Min Ji, Ki Pyo Sung, Choong Hyeon Kim
Background The initial redness of the scar on a postoperative suture site is a natural phenomenon that fades over time. However, with a long period of redness, patients complain about cosmetic discomfort, and the possibility of pigmentation changes is induced. We investigated the use of a long-pulsed 1064 nm Nd:YAG laser as a noninvasive treatment for improving the redness of these scars.Methods A retrospective chart review was conducted on 36 patients who underwent excision of a nevus on the face. Fourteen patients received laser treatment and another 22 patients used only scar management ointment. Patients were followed up 1 week after the sutures were removed. The photographic images taken at the time of suture removal and 2 months later were reviewed. The evaluation was performed on a 7-point scale by adding the Japan Scar Workshop (JSW) scar scale’s redness and erythema scores.Results The average initial JSW scar scale score of the treatment group was 4.6, and that of the nontreatment group was 4.2. When the re-evaluation was performed 2 months later, the score of the treatment group decreased to 2.2 and that of the nontreatment group decreased to 3.1. The difference in the JSW scar scale between the treatment group and the nontreatment group according to laser performance was statistically significant (P=0.03).Conclusions The treatment method with a long-pulsed 1064 nm Nd:YAG laser that is less invasive and has a quick effect can be a good alternative for improving this initial scar redness.
{"title":"Efficacy of a long-pulsed 1064-nm Nd:YAG laser in acute scar redness","authors":"Y. Choi, Jeong-Min Ji, Ki Pyo Sung, Choong Hyeon Kim","doi":"10.14730/aaps.2023.00843","DOIUrl":"https://doi.org/10.14730/aaps.2023.00843","url":null,"abstract":"Background The initial redness of the scar on a postoperative suture site is a natural phenomenon that fades over time. However, with a long period of redness, patients complain about cosmetic discomfort, and the possibility of pigmentation changes is induced. We investigated the use of a long-pulsed 1064 nm Nd:YAG laser as a noninvasive treatment for improving the redness of these scars.Methods A retrospective chart review was conducted on 36 patients who underwent excision of a nevus on the face. Fourteen patients received laser treatment and another 22 patients used only scar management ointment. Patients were followed up 1 week after the sutures were removed. The photographic images taken at the time of suture removal and 2 months later were reviewed. The evaluation was performed on a 7-point scale by adding the Japan Scar Workshop (JSW) scar scale’s redness and erythema scores.Results The average initial JSW scar scale score of the treatment group was 4.6, and that of the nontreatment group was 4.2. When the re-evaluation was performed 2 months later, the score of the treatment group decreased to 2.2 and that of the nontreatment group decreased to 3.1. The difference in the JSW scar scale between the treatment group and the nontreatment group according to laser performance was statistically significant (P=0.03).Conclusions The treatment method with a long-pulsed 1064 nm Nd:YAG laser that is less invasive and has a quick effect can be a good alternative for improving this initial scar redness.","PeriodicalId":41514,"journal":{"name":"Archives of Aesthetic Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44475513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-31DOI: 10.14730/aaps.2023.00857
Joo-Hak Kim, Yunsung Park, Ho Jik Yang, Sang-Ha Oh, S. Song, Yooseok Ha, Sunje Kim, H. Kyung
A 25-year-old woman was referred for discomfort when breathing through her left nose. The patient had undergone augmentation rhinoplasty 5 years ago, after which hypertrophic scarring occurred in the left nostril. Several corticosteroid injections were administered as the first line of treatment, but with no symptom improvement. Therefore, we proceeded with surgical scar removal, with the use of a nasal conformer. However, scarring in the left nostril recurred. Accordingly, we proceeded with further surgical treatment using the scar folding technique. After scar folding, neither scarring nor nostril stenosis recurred during 1 year of postoperative follow-up. To summarize, herein, we report a case of hypertrophic scarring in the nostril that was successfully treated with the scar folding technique.
{"title":"Scar folding for the treatment of nostril stenosis after open rhinoplasty: a case report","authors":"Joo-Hak Kim, Yunsung Park, Ho Jik Yang, Sang-Ha Oh, S. Song, Yooseok Ha, Sunje Kim, H. Kyung","doi":"10.14730/aaps.2023.00857","DOIUrl":"https://doi.org/10.14730/aaps.2023.00857","url":null,"abstract":"A 25-year-old woman was referred for discomfort when breathing through her left nose. The patient had undergone augmentation rhinoplasty 5 years ago, after which hypertrophic scarring occurred in the left nostril. Several corticosteroid injections were administered as the first line of treatment, but with no symptom improvement. Therefore, we proceeded with surgical scar removal, with the use of a nasal conformer. However, scarring in the left nostril recurred. Accordingly, we proceeded with further surgical treatment using the scar folding technique. After scar folding, neither scarring nor nostril stenosis recurred during 1 year of postoperative follow-up. To summarize, herein, we report a case of hypertrophic scarring in the nostril that was successfully treated with the scar folding technique.","PeriodicalId":41514,"journal":{"name":"Archives of Aesthetic Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47624971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-31DOI: 10.14730/aaps.2023.00822
K. Hwang
When I encounter a patient with a fractured nose, I tell them that the goal of closed reduction is not to obtain a straight nose, but to return to the state before injury. I show deviation of the nasal septum on the axial view of computed tomography and show that it cannot be straightened at this time. In the preoperative design of upper blepharoplasty in elderly patients, the extent of excision is not the same in both eyelids. Usually, laxity is more severer on one side than on the other side. Patients planning to undergo aesthetic procedures often want to make their faces symmetrical. A symmetrical face has often been regarded as a feature of true beauty, and many movie stars are hailed for their mirror-image looks. However, a perfectly symmetrical face is quite rare. Facial symmetry is observed in only 2% of the world’s population. For example, Amber Laura Heard (1986) (Fig. 1), an American actress who plays leading roles in horror films, is regarded as having a perfectly symmetrical face. Some degree of congenital or acquired asymmetry is normal and universal. Significant facial asymmetry, however, causes both aesthetic and functional problems [1]. Factors such as aging, trauma, and lifestyle choices, such as smoking or sun exposure, may contribute to asymmetry. Sometimes an asymmetrical face is the result of an individual’s genetics. There is a link between increasing age and facial asymmetry. Smoking exposes the face to toxins and can cause vascular problems. Excessive exposure to ultraviolet rays can also cause an asymmetrical face. Trauma, such as a broken nose, a deep cut, or being involved in a vehicle collision, can damage the face. Furthermore, using dentures or getting dental veneers may change the contours of the face. If a person has always had asymmetrical features, there is no cause for concern. However, new and noticeable facial asymmetry may be a sign of a serious underlying condition, such as stroke or Bell’s palsy. Facial drooping may be a sign of a stroke. Bell’s palsy is a condition involving paralysis of the facial nerves, usually causing one side of the face to droop [2]. When patients complain of facial asymmetry, the underlying cause should be investigated. Its causes are congenital disorders, acquired diseases, and traumatic and developmental deformities. Many cases of developmental facial asymmetry have indistinct causes. An appropriate assessment includes the patient’s history, a physical examination, and medical imaging [3]. When my patients want perfect symmetry, I usually quote a sentence from Murder on the Orient Express, written by Agatha Christie (1890–1976). Hercule Poirot says, “I was looking forward to seeing La Sainte Sophie. I love cathedrals. Mankind imposing order on the chaos, impossible symmetry. The most beautiful woman I ever saw had two different colored eyes, one blue one green” (heterochromia iridis).
当我遇到一个鼻子骨折的病人时，我告诉他们，闭合复位的目标不是获得直鼻，而是恢复到受伤前的状态。我在计算机断层扫描的轴向视图上显示了鼻中隔的偏移，并表明此时无法拉直。在老年患者上眼睑整形术的术前设计中，双眼皮的切除程度不同。通常，一侧的松懈比另一侧更严重。计划接受美容手术的患者通常希望自己的脸对称。对称的脸通常被认为是真正美丽的特征，许多电影明星因其镜像形象而受到赞誉。然而，一张完全对称的脸是非常罕见的。全世界只有2%的人口面部对称。例如，Amber Laura Heard（1986）（图1），一位在恐怖电影中扮演主角的美国女演员，被认为有一张完美对称的脸。某种程度的先天性或后天性不对称是正常和普遍的。然而，显著的面部不对称会导致审美和功能问题[1]。衰老、创伤和生活方式选择（如吸烟或日晒）等因素可能会导致不对称。有时不对称的脸是个体遗传的结果。年龄的增长和面部不对称之间存在联系。吸烟会使面部暴露在毒素中，并可能导致血管问题。过度暴露在紫外线下也会导致面部不对称。外伤，如鼻子骨折、深深的伤口或车辆碰撞，都会损伤面部。此外，使用假牙或使用贴面可能会改变面部轮廓。如果一个人总是有不对称的特征，那就没有理由担心。然而，新出现的明显面部不对称可能是严重潜在疾病的征兆，如中风或贝尔氏麻痹。面部下垂可能是中风的征兆。贝尔麻痹是一种涉及面部神经麻痹的疾病，通常会导致一侧面部下垂[2]。当患者抱怨面部不对称时，应调查其根本原因。其病因包括先天性疾病、后天性疾病、创伤和发育畸形。许多发育性面部不对称的原因不明。适当的评估包括患者的病史、身体检查和医学成像[3]。当我的病人想要完美对称时，我通常会引用阿加莎·克里斯蒂（1890–1976）的《东方快车谋杀案》中的一句话。Hercule Poirot说：“我很期待看到La Sainte Sophie。我喜欢大教堂。人类在混乱中强加秩序，不可能对称。我见过的最漂亮的女人有两只不同颜色的眼睛，一只蓝一只绿。”。
{"title":"Impossible symmetry","authors":"K. Hwang","doi":"10.14730/aaps.2023.00822","DOIUrl":"https://doi.org/10.14730/aaps.2023.00822","url":null,"abstract":"When I encounter a patient with a fractured nose, I tell them that the goal of closed reduction is not to obtain a straight nose, but to return to the state before injury. I show deviation of the nasal septum on the axial view of computed tomography and show that it cannot be straightened at this time. In the preoperative design of upper blepharoplasty in elderly patients, the extent of excision is not the same in both eyelids. Usually, laxity is more severer on one side than on the other side. Patients planning to undergo aesthetic procedures often want to make their faces symmetrical. A symmetrical face has often been regarded as a feature of true beauty, and many movie stars are hailed for their mirror-image looks. However, a perfectly symmetrical face is quite rare. Facial symmetry is observed in only 2% of the world’s population. For example, Amber Laura Heard (1986) (Fig. 1), an American actress who plays leading roles in horror films, is regarded as having a perfectly symmetrical face. Some degree of congenital or acquired asymmetry is normal and universal. Significant facial asymmetry, however, causes both aesthetic and functional problems [1]. Factors such as aging, trauma, and lifestyle choices, such as smoking or sun exposure, may contribute to asymmetry. Sometimes an asymmetrical face is the result of an individual’s genetics. There is a link between increasing age and facial asymmetry. Smoking exposes the face to toxins and can cause vascular problems. Excessive exposure to ultraviolet rays can also cause an asymmetrical face. Trauma, such as a broken nose, a deep cut, or being involved in a vehicle collision, can damage the face. Furthermore, using dentures or getting dental veneers may change the contours of the face. If a person has always had asymmetrical features, there is no cause for concern. However, new and noticeable facial asymmetry may be a sign of a serious underlying condition, such as stroke or Bell’s palsy. Facial drooping may be a sign of a stroke. Bell’s palsy is a condition involving paralysis of the facial nerves, usually causing one side of the face to droop [2]. When patients complain of facial asymmetry, the underlying cause should be investigated. Its causes are congenital disorders, acquired diseases, and traumatic and developmental deformities. Many cases of developmental facial asymmetry have indistinct causes. An appropriate assessment includes the patient’s history, a physical examination, and medical imaging [3]. When my patients want perfect symmetry, I usually quote a sentence from Murder on the Orient Express, written by Agatha Christie (1890–1976). Hercule Poirot says, “I was looking forward to seeing La Sainte Sophie. I love cathedrals. Mankind imposing order on the chaos, impossible symmetry. The most beautiful woman I ever saw had two different colored eyes, one blue one green” (heterochromia iridis).","PeriodicalId":41514,"journal":{"name":"Archives of Aesthetic Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45476867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-31DOI: 10.14730/aaps.2022.00773
A. Unlu, Muhammet Volkan Bulbul, Bircan Kolbasi Erkan, İlkay Ozdemir, I. Keskin, M. Sutcu
Background Since cartilage, unlike skin, does not contain vessels, it obtains nutrition by diffusion. This reduces graft viability, resulting in problems such as reductions in size, changes in shape, and resorption of the cartilage graft in the late post-graft period. This study aimed to investigate the effects of adipose-derived mesenchymal cells and conditioned medium (CM) on cartilage graft viability.Methods Dissections were performed 4 months after the injection of 0.5 mL of CM or 2×106 mesenchymal stem cells (MSCs) in 0.5 mL after grafting into a control group and two experimental groups (n=21 rabbits in total). Chondrocyte viability and type II collagen expression in the grafted areas were analyzed by hematoxylin-eosin staining and immunohistochemical methods, respectively.Results In the MSC and CM groups, chondrocyte proliferation at the graft tissue incision margin (MSC: P<0.01, CM: P<0.0001), chondrocyte proliferation at the auricular cartilage incision margin (MSC: P<0.05, CM: P<0.0001), integration of the graft with the surrounding cartilage (MSC: P<0.001, CM: P<0.0001) and type II collagen expression levels (MSC: P=0.001, CM: P=0.0002) significantly increased.Conclusions Xenogenic injection of MSCs and CM contributed to new cartilage production without any tumoral effects or immune reactions. In particular, the cell-free nature of CM strengthened its potential for safe use. Since injections of MSC and CM can preserve cartilage graft viability, interest in this technique is expected to increase as long-term results from clinical studies on the subject become available.
与皮肤不同，软骨不含血管，它通过扩散获得营养。这降低了移植物的生存能力，导致诸如大小缩小、形状改变和移植后后期软骨移植物的吸收等问题。本研究旨在探讨脂肪源性间充质细胞和条件培养基(CM)对软骨移植物活力的影响。方法将0.5 mL CM或0.5 mL 2×106间充质干细胞(MSCs)移植后注入对照组和2个实验组(共21只)，4个月后进行解剖。采用苏木精-伊红染色法和免疫组化法分别分析移植区软骨细胞活力和II型胶原表达。结果MSC组和CM组移植物组织切口缘软骨细胞增殖(MSC: P<0.01, CM: P<0.0001)、耳软骨切口缘软骨细胞增殖(MSC: P<0.05, CM: P<0.0001)、移植物与周围软骨融合(MSC: P<0.001, CM: P<0.0001)和II型胶原表达水平(MSC: P=0.001, CM: P=0.0002)均显著增加。结论异种注射MSCs和CM可促进新生软骨生成，无肿瘤效应和免疫反应。特别是，CM的无细胞特性增强了其安全使用的潜力。由于注射骨髓间充质干细胞和骨髓间充质干细胞可以保持软骨移植物的活力，随着临床研究的长期结果的出现，人们对这项技术的兴趣有望增加。
{"title":"Examination of the effect of xenogeneic mesenchymal stem cells and conditioned medium on cartilage graft viability: a rabbit model","authors":"A. Unlu, Muhammet Volkan Bulbul, Bircan Kolbasi Erkan, İlkay Ozdemir, I. Keskin, M. Sutcu","doi":"10.14730/aaps.2022.00773","DOIUrl":"https://doi.org/10.14730/aaps.2022.00773","url":null,"abstract":"Background Since cartilage, unlike skin, does not contain vessels, it obtains nutrition by diffusion. This reduces graft viability, resulting in problems such as reductions in size, changes in shape, and resorption of the cartilage graft in the late post-graft period. This study aimed to investigate the effects of adipose-derived mesenchymal cells and conditioned medium (CM) on cartilage graft viability.Methods Dissections were performed 4 months after the injection of 0.5 mL of CM or 2×106 mesenchymal stem cells (MSCs) in 0.5 mL after grafting into a control group and two experimental groups (n=21 rabbits in total). Chondrocyte viability and type II collagen expression in the grafted areas were analyzed by hematoxylin-eosin staining and immunohistochemical methods, respectively.Results In the MSC and CM groups, chondrocyte proliferation at the graft tissue incision margin (MSC: P<0.01, CM: P<0.0001), chondrocyte proliferation at the auricular cartilage incision margin (MSC: P<0.05, CM: P<0.0001), integration of the graft with the surrounding cartilage (MSC: P<0.001, CM: P<0.0001) and type II collagen expression levels (MSC: P=0.001, CM: P=0.0002) significantly increased.Conclusions Xenogenic injection of MSCs and CM contributed to new cartilage production without any tumoral effects or immune reactions. In particular, the cell-free nature of CM strengthened its potential for safe use. Since injections of MSC and CM can preserve cartilage graft viability, interest in this technique is expected to increase as long-term results from clinical studies on the subject become available.","PeriodicalId":41514,"journal":{"name":"Archives of Aesthetic Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45458037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-31DOI: 10.14730/aaps.2022.00689
J. Seo, Seung Hyun Kim, Jae Woo Lee, Min Wook Kim, Dae Kyun Jeong, S. Bae, Hyun Yul Kim, Y. Jung, S. Nam
Background Implant-based immediate breast reconstruction surgery with nipple-sparing mastectomy has recently been favored by patients. However, in patients who do not wish to undergo balancing procedures, it is difficult to select the appropriate implant size, making it challenging to achieve a symmetrical breast shape. Therefore, this study investigated the differences in breast asymmetry and other complications in patients who underwent a two-stage procedure or direct-to-implant (DTI) breast reconstruction to determine whether the two-stage procedure can produce more favorable outcomes.Methods The participants of this study were patients who underwent immediate two-stage breast reconstruction or DTI breast reconstruction from May 2018 to April 2022, did not receive postoperative radiotherapy, and did not wish to undergo any balancing procedures. An acellular dermal matrix was used for breast reconstruction in all patients, and a single reconstructive surgeon performed all the operations. Statistical significance was set at P<0.05.Results No significant differences in complications were found between the patients who underwent DTI breast reconstruction and those who underwent two-stage breast reconstruction. In the two-stage breast reconstruction group, breast volume asymmetry was observed in 18.4% (seven patients), which was significantly lower than the percentage of 44.7% (17 patients) observed in the DTI group.Conclusions Breast asymmetry was observed in a significant proportion of the patients in both groups. However, because breast volume asymmetry was more common in the DTI group than in the two-stage breast reconstruction group, two-stage breast reconstruction may be a favorable method for patients who do not wish to undergo balancing procedures.
{"title":"Differences in complications and asymmetry in patients who did not receive a balancing procedure in two-stage and direct-to-implant breast reconstruction","authors":"J. Seo, Seung Hyun Kim, Jae Woo Lee, Min Wook Kim, Dae Kyun Jeong, S. Bae, Hyun Yul Kim, Y. Jung, S. Nam","doi":"10.14730/aaps.2022.00689","DOIUrl":"https://doi.org/10.14730/aaps.2022.00689","url":null,"abstract":"Background Implant-based immediate breast reconstruction surgery with nipple-sparing mastectomy has recently been favored by patients. However, in patients who do not wish to undergo balancing procedures, it is difficult to select the appropriate implant size, making it challenging to achieve a symmetrical breast shape. Therefore, this study investigated the differences in breast asymmetry and other complications in patients who underwent a two-stage procedure or direct-to-implant (DTI) breast reconstruction to determine whether the two-stage procedure can produce more favorable outcomes.Methods The participants of this study were patients who underwent immediate two-stage breast reconstruction or DTI breast reconstruction from May 2018 to April 2022, did not receive postoperative radiotherapy, and did not wish to undergo any balancing procedures. An acellular dermal matrix was used for breast reconstruction in all patients, and a single reconstructive surgeon performed all the operations. Statistical significance was set at P<0.05.Results No significant differences in complications were found between the patients who underwent DTI breast reconstruction and those who underwent two-stage breast reconstruction. In the two-stage breast reconstruction group, breast volume asymmetry was observed in 18.4% (seven patients), which was significantly lower than the percentage of 44.7% (17 patients) observed in the DTI group.Conclusions Breast asymmetry was observed in a significant proportion of the patients in both groups. However, because breast volume asymmetry was more common in the DTI group than in the two-stage breast reconstruction group, two-stage breast reconstruction may be a favorable method for patients who do not wish to undergo balancing procedures.","PeriodicalId":41514,"journal":{"name":"Archives of Aesthetic Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43395942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-31DOI: 10.14730/aaps.2023.00801
Y. Chung, Min-Seok Kim, J. Shin, Nae-Ho Lee, H. Park, Si-Gyun Roh
Advances in plastic surgery have included a shift toward less invasive procedures. To improve outcomes and avoid incisional surgery, numerous noninvasive face-lifting techniques have been studied. This includes thread-lifting, a technique that promises to correct facial aging with limited scarring, rapid recovery, and minimal complications. As the population ages, an increasing number of ordinary people in South Korea are undergoing thread lifting procedures for the purpose of rejuvenation. The procedure involves insertion of a thread under the skin into the subcutaneous tissue, using a long needle as a guide. Dents or barbs prevent the thread from slipping and provide uniform aggregation of soft tissue to create a new volume contour when the thread is lifted. This procedure has gained worldwide popularity and is frequently performed. However, some minor complications have been reported. In this paper, we report an unusual complication: an obstructive stone in the parotid (Stensen) duct after a thread-lifting procedure using nonabsorbable anchoring threads.
{"title":"Case report of unusual complication following thread lifting: an obstructive stone in the parotid duct","authors":"Y. Chung, Min-Seok Kim, J. Shin, Nae-Ho Lee, H. Park, Si-Gyun Roh","doi":"10.14730/aaps.2023.00801","DOIUrl":"https://doi.org/10.14730/aaps.2023.00801","url":null,"abstract":"Advances in plastic surgery have included a shift toward less invasive procedures. To improve outcomes and avoid incisional surgery, numerous noninvasive face-lifting techniques have been studied. This includes thread-lifting, a technique that promises to correct facial aging with limited scarring, rapid recovery, and minimal complications. As the population ages, an increasing number of ordinary people in South Korea are undergoing thread lifting procedures for the purpose of rejuvenation. The procedure involves insertion of a thread under the skin into the subcutaneous tissue, using a long needle as a guide. Dents or barbs prevent the thread from slipping and provide uniform aggregation of soft tissue to create a new volume contour when the thread is lifted. This procedure has gained worldwide popularity and is frequently performed. However, some minor complications have been reported. In this paper, we report an unusual complication: an obstructive stone in the parotid (Stensen) duct after a thread-lifting procedure using nonabsorbable anchoring threads.","PeriodicalId":41514,"journal":{"name":"Archives of Aesthetic Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46931516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-31DOI: 10.14730/aaps.2021.00773
Jang Won Lee, Seong Heum Jeong, Seung-Hyun Oh, C. Kim
Background Capsular contracture is the most common serious breast surgery complication. The cause of capsular formation remains unknown, but chronic inflammation is commonly considered to cause excessive fibrosis. Curcumin has anti-inflammatory effects and thus can relieve the symptoms of inflammatory diseases, as demonstrated in animal studies. This study aimed to evaluate the effects of curcumin on the fibrous envelope covering silicone implants in a rat model.Methods Two solid 1.8-cm oval-shaped silicone implants were placed beneath both sides of the back in 20 Sprague-Dawley rats. The control group included 10 rats that were fed a normal diet (group A), while the experimental group (group B) included the remaining 10 rats that were fed ground curcumin. En bloc excision was conducted at 8 postoperative weeks. Capsular thickness and inflammatory cell distribution were examined using a fixed tissue sample.Results Gross findings and histologic differences between the groups were observed. The experimental group had a significantly lower mean total capsular thickness than the control group (177.4±31.4 μm vs. 145.9±32.5 μm, P=0.007). A significant decreasing tendency was found in several inflammatory cells in the experimental group (7,070±744.3/mm2 vs. 2,640±301.7/mm2, P=0.001).Conclusions Curcumin significantly reduced the inflammatory reaction, and will help to lower the risk of capsular contracture. Long-term studies are required to determine whether this hypothesis can provide a basis for a viable therapeutic strategy to reduce capsular contracture.
背景:乳房包膜挛缩是乳房手术中最常见的严重并发症。荚膜形成的原因尚不清楚，但慢性炎症通常被认为是导致过度纤维化的原因。姜黄素具有抗炎作用，因此可以缓解炎症性疾病的症状，这在动物研究中得到证实。本研究旨在评价姜黄素对大鼠硅胶植入物纤维包膜的影响。方法将2个实心1.8 cm椭圆形硅胶植入物置于20只sd大鼠背部下方。对照组10只大鼠饲喂正常饮食(a组)，试验组(B组)其余10只大鼠饲喂姜黄素粉。术后8周进行整体切除。使用固定组织样本检查荚膜厚度和炎症细胞分布。结果观察两组大体表现及组织学差异。实验组的平均囊膜厚度明显低于对照组(177.4±31.4 μm∶145.9±32.5 μm, P=0.007)。实验组几种炎症细胞有明显下降趋势(7070±744.3/mm2 vs. 2640±301.7/mm2, P=0.001)。结论姜黄素可明显降低炎症反应，降低包膜挛缩的发生风险。需要长期的研究来确定这一假设是否可以为减少包膜挛缩的可行治疗策略提供基础。
{"title":"The effects of curcumin on the fibrous envelope surrounding silicone implants in rats","authors":"Jang Won Lee, Seong Heum Jeong, Seung-Hyun Oh, C. Kim","doi":"10.14730/aaps.2021.00773","DOIUrl":"https://doi.org/10.14730/aaps.2021.00773","url":null,"abstract":"Background Capsular contracture is the most common serious breast surgery complication. The cause of capsular formation remains unknown, but chronic inflammation is commonly considered to cause excessive fibrosis. Curcumin has anti-inflammatory effects and thus can relieve the symptoms of inflammatory diseases, as demonstrated in animal studies. This study aimed to evaluate the effects of curcumin on the fibrous envelope covering silicone implants in a rat model.Methods Two solid 1.8-cm oval-shaped silicone implants were placed beneath both sides of the back in 20 Sprague-Dawley rats. The control group included 10 rats that were fed a normal diet (group A), while the experimental group (group B) included the remaining 10 rats that were fed ground curcumin. En bloc excision was conducted at 8 postoperative weeks. Capsular thickness and inflammatory cell distribution were examined using a fixed tissue sample.Results Gross findings and histologic differences between the groups were observed. The experimental group had a significantly lower mean total capsular thickness than the control group (177.4±31.4 μm vs. 145.9±32.5 μm, P=0.007). A significant decreasing tendency was found in several inflammatory cells in the experimental group (7,070±744.3/mm2 vs. 2,640±301.7/mm2, P=0.001).Conclusions Curcumin significantly reduced the inflammatory reaction, and will help to lower the risk of capsular contracture. Long-term studies are required to determine whether this hypothesis can provide a basis for a viable therapeutic strategy to reduce capsular contracture.","PeriodicalId":41514,"journal":{"name":"Archives of Aesthetic Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47817049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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