Pub Date : 2021-08-01DOI: 10.4274/tod.galenos.2020.47855
Senem Şaş, Fatmanur Aybala Koçak, B. Büyükturan, Ö. Büyükturan
Objective: This study aimed to determine the relationship between vitamin D levels and anxiety and depression in patients with chronic pain. Materials and Methods: A total of 160 patients, including 125 female and 35 male patients, who were >18 years old and capable of answering study questions were included in this study. Age, gender, height, weight, duration of disease, diagnosis and comorbid status of the patients were recorded. Body mass index (BMI) (kg/m 2 ) was calculated for each patient. Pain was evaluated using the visual analogue scale (VAS), which ranges from 0 to 10. Hospital anxiety and depression scale (HADS) scores were recorded. The patients were divided into two groups (group 1 vitamin D: 0-19, group 2 vitamin D: 20-60 ng/mL) according to vitamin D levels. Also vitamin D levels were noted. Results: The mean age of the patients included in this study was 58.72±8.21 years. Vitamin D deficiency was found in 42.8% of the patients, of which 80.7% were female patients.In patients with chronic pain, there was no correlation between vitamin D levels and age (r=0.185, p=0.026); BMI (r=0.084, p=0.316); disease duration (r=0.067, p=0.420); VAS (r=0.038, p=0.648); HADS scores for anxiety (r=0.020, p=0.808) and HADS scores for depression (r=0.048, p=0.569). No relationship was noted between BMI and vitamin D levels (r =-0.117, p=0.165) in patients with chronic pain; however, a positive correlation was noted between BMI and VAS (r=0.305, p=0.000) and HADS scores for anxiety (r=0.185, p=0.001) and HADS scores for depression (r=0.0240, p=0.002). Abstract Conclusion: In the present study, we found no relationship between vitamin D levels and anxiety and depression in patients with chronic pain. However, we found a correlation between obesity and pain severity. Also we report that obesity is associated with anxiety and depression. Implementing lifestyle changes, such as weight loss and reduction of vitamin D deficiency, can improve anxiety and depression in patients with chronic pain.
{"title":"Evaluation of the Relationship Between Vitamin D Levels and Anxiety and Depression in Patients with Chronic Pain","authors":"Senem Şaş, Fatmanur Aybala Koçak, B. Büyükturan, Ö. Büyükturan","doi":"10.4274/tod.galenos.2020.47855","DOIUrl":"https://doi.org/10.4274/tod.galenos.2020.47855","url":null,"abstract":"Objective: This study aimed to determine the relationship between vitamin D levels and anxiety and depression in patients with chronic pain. Materials and Methods: A total of 160 patients, including 125 female and 35 male patients, who were >18 years old and capable of answering study questions were included in this study. Age, gender, height, weight, duration of disease, diagnosis and comorbid status of the patients were recorded. Body mass index (BMI) (kg/m 2 ) was calculated for each patient. Pain was evaluated using the visual analogue scale (VAS), which ranges from 0 to 10. Hospital anxiety and depression scale (HADS) scores were recorded. The patients were divided into two groups (group 1 vitamin D: 0-19, group 2 vitamin D: 20-60 ng/mL) according to vitamin D levels. Also vitamin D levels were noted. Results: The mean age of the patients included in this study was 58.72±8.21 years. Vitamin D deficiency was found in 42.8% of the patients, of which 80.7% were female patients.In patients with chronic pain, there was no correlation between vitamin D levels and age (r=0.185, p=0.026); BMI (r=0.084, p=0.316); disease duration (r=0.067, p=0.420); VAS (r=0.038, p=0.648); HADS scores for anxiety (r=0.020, p=0.808) and HADS scores for depression (r=0.048, p=0.569). No relationship was noted between BMI and vitamin D levels (r =-0.117, p=0.165) in patients with chronic pain; however, a positive correlation was noted between BMI and VAS (r=0.305, p=0.000) and HADS scores for anxiety (r=0.185, p=0.001) and HADS scores for depression (r=0.0240, p=0.002). Abstract Conclusion: In the present study, we found no relationship between vitamin D levels and anxiety and depression in patients with chronic pain. However, we found a correlation between obesity and pain severity. Also we report that obesity is associated with anxiety and depression. Implementing lifestyle changes, such as weight loss and reduction of vitamin D deficiency, can improve anxiety and depression in patients with chronic pain.","PeriodicalId":41797,"journal":{"name":"Turk Osteoporoz Dergisi-Turkish Journal of Osteoporosis","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72775388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-01DOI: 10.4274/tod.galenos.2021.09815
S. Satış, A. Yetişgin
Objective: To investigate the effects of wearing mask and lockdowns during the coronavirus disease-2019 (COVID-19) pandemic on the vitamin D levels in females. Materials and Methods: This retrospective study included female adults aged 18-64 years who underwent vitamin D evaluation at our hospital in April and May from 2017 to 2020. Vitamin D levels were categorized as follows: 30 ng/mL (normal). Results: A total of 835 (90.8%) out of 920 females had vitamin D deficiency, and among them 463 (50.3%) had vitamin D severe deficiency. In April and May of 2020 (during the national lockdown period), 74 (89.2%) out of 83 subjects had vitamin D deficiency. Vitamin D levels were found to be higher in 2017 than the other years (p 0.05). Conclusion: Our findings indicate that there is a serious and urgent public health problem regarding with vitamin D deficiency (>90%) in our population;and about 50% of them had severe deficiency. This problem was not different during the lockdown period compared with the previous two years. (English) [ABSTRACT FROM AUTHOR] Amac: Koronavirus hastaligi-2019 (COVID-19) pandemisi sirasinda maske takmanin ve sokaga cikma yasaginin kadinlarda D vitamini duzeyleri uzerindeki etkilerini arastirmaktir. Gerec ve Yontem: Bu retrospektif calismaya 2017-2020 yillari arasinda Nisan ve Mayis aylarinda hastanemizde D vitamini degerlendirmesi yapilan 18-64 yas arasi eriskin kadinlar dahil edildi. D vitamini duzeyleri su sekilde kategorize edildi: 30 ng/mL (normal). Bulgular: Dokuz yuz yirmi kadindan toplam 835'inde (%90,8) D vitamini eksikligi, 463'unde (%50,3) ciddi D vitamini eksikligi vardi. 2020 yilinin Nisan ve Mayis aylarinda (ulusal karantina doneminde), 83 kisiden 74'unde (%89,2) D vitamini eksikligi vardi. 2017 yilinda D vitamini duzeyleri diger yillara gore daha yuksek bulundu (p 0,05). Sonuc: Bulgularimiz toplumumuzda D vitamini eksikligi (>%90) ile ilgili ciddi ve acil bir halk sagligi sorunu oldugunu gostermektedir;ve yaklasik %50'sinde ciddi eksiklik vardir. Bu sorun, karantina doneminde onceki iki yila kiyasla farkli degildir. (Turkish) [ABSTRACT FROM AUTHOR] Copyright of Turkish Journal of Osteoporosis / Turk Osteoporoz Dergisi is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
目的:探讨冠状病毒病(COVID-19)大流行期间戴口罩和封锁对女性维生素D水平的影响。材料与方法:本回顾性研究纳入2017 - 2020年4 - 5月在我院进行维生素D评估的18-64岁女性成年人。维生素D水平分类如下:30纳克/毫升(正常)。结果:920名女性中有835人(90.8%)存在维生素D缺乏症，其中重度维生素D缺乏症463人(50.3%)。在2020年4月和5月(全国封锁期间)，83名受试者中有74人(89.2%)缺乏维生素D。2017年的维生素D水平高于其他年份(p < 0.05)。结论:我们的研究结果表明，在我国人口中，维生素D缺乏症是一个严重而紧迫的公共卫生问题(约90%)，其中约50%的人严重缺乏维生素D。这一问题在封锁期间与前两年没有什么不同。摘要/ ABSTRACT摘要/作者简介:2019冠状病毒(COVID-19)大流行的sirasinda口罩takmanin ve sokaga cikma yasaginin kadinlarda D维生素duzeyleri uzerindeki etkilerini arasirmaktir。研究项目:回顾性分析2017-2020年枸杞枸杞中维生素D的含量，分析枸杞枸杞中维生素D的含量，分析枸杞枸杞中维生素D的含量。维生素D: 30 ng/mL(正常)。品种:Dokuz yuz yirmi kadindan toplam 835' index (%90,8) D vitamini eksikligi, 463' index (%50,3) ciddi D vitamini eksikligi vardi。2020年1月1日，1年1月1日，1年2月1日，1年3月1日，1年3月1日，1年3月1日，1年3月1日。2017 yilinda D维生素duzeyleri, diger, yillara, yillara, yillara, yillard . [p];[关键词]bulgulariziz - plumumuzda D vitaminiekkkligi (b> %90)， ilgili - cidive, halk sagligi sorunu, oldugunu gostermektedir, yyaklasik %50' in cididekklik vardir。但是，卡兰蒂娜doneminde onceki iki yila kiyasla farkli degildir。[摘要]土耳其骨质疏松症杂志版权所有/ Turk骨质疏松症Dergisi是Galenos Yayinevi Tic的财产。有限公司未经版权所有者的明确书面许可，STI及其内容不得复制或通过电子邮件发送到多个网站或发布到listserv。但是，用户可以打印、下载或通过电子邮件发送文章供个人使用。这篇摘要可以删节。对副本的准确性不作任何保证。用户应参考资料的原始出版版本以获取完整摘要。(版权适用于所有摘要。)
{"title":"Did Wearing Mask and Lockdowns Affect Vitamin D Levels During the Coronavirus Disease-2019 Pandemic?","authors":"S. Satış, A. Yetişgin","doi":"10.4274/tod.galenos.2021.09815","DOIUrl":"https://doi.org/10.4274/tod.galenos.2021.09815","url":null,"abstract":"Objective: To investigate the effects of wearing mask and lockdowns during the coronavirus disease-2019 (COVID-19) pandemic on the vitamin D levels in females. Materials and Methods: This retrospective study included female adults aged 18-64 years who underwent vitamin D evaluation at our hospital in April and May from 2017 to 2020. Vitamin D levels were categorized as follows: 30 ng/mL (normal). Results: A total of 835 (90.8%) out of 920 females had vitamin D deficiency, and among them 463 (50.3%) had vitamin D severe deficiency. In April and May of 2020 (during the national lockdown period), 74 (89.2%) out of 83 subjects had vitamin D deficiency. Vitamin D levels were found to be higher in 2017 than the other years (p 0.05). Conclusion: Our findings indicate that there is a serious and urgent public health problem regarding with vitamin D deficiency (>90%) in our population;and about 50% of them had severe deficiency. This problem was not different during the lockdown period compared with the previous two years. (English) [ABSTRACT FROM AUTHOR] Amac: Koronavirus hastaligi-2019 (COVID-19) pandemisi sirasinda maske takmanin ve sokaga cikma yasaginin kadinlarda D vitamini duzeyleri uzerindeki etkilerini arastirmaktir. Gerec ve Yontem: Bu retrospektif calismaya 2017-2020 yillari arasinda Nisan ve Mayis aylarinda hastanemizde D vitamini degerlendirmesi yapilan 18-64 yas arasi eriskin kadinlar dahil edildi. D vitamini duzeyleri su sekilde kategorize edildi: 30 ng/mL (normal). Bulgular: Dokuz yuz yirmi kadindan toplam 835'inde (%90,8) D vitamini eksikligi, 463'unde (%50,3) ciddi D vitamini eksikligi vardi. 2020 yilinin Nisan ve Mayis aylarinda (ulusal karantina doneminde), 83 kisiden 74'unde (%89,2) D vitamini eksikligi vardi. 2017 yilinda D vitamini duzeyleri diger yillara gore daha yuksek bulundu (p 0,05). Sonuc: Bulgularimiz toplumumuzda D vitamini eksikligi (>%90) ile ilgili ciddi ve acil bir halk sagligi sorunu oldugunu gostermektedir;ve yaklasik %50'sinde ciddi eksiklik vardir. Bu sorun, karantina doneminde onceki iki yila kiyasla farkli degildir. (Turkish) [ABSTRACT FROM AUTHOR] Copyright of Turkish Journal of Osteoporosis / Turk Osteoporoz Dergisi is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)","PeriodicalId":41797,"journal":{"name":"Turk Osteoporoz Dergisi-Turkish Journal of Osteoporosis","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88261492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-01DOI: 10.4274/tod.galenos.2020.85688
Salim Mısırcı, Y. Akyol, Y. Ulus, A. Cengiz, A. Bilgici
{"title":"Kinesiophobia and Related Factors in Postmenopausal Women with Osteoporosis and Osteopenia","authors":"Salim Mısırcı, Y. Akyol, Y. Ulus, A. Cengiz, A. Bilgici","doi":"10.4274/tod.galenos.2020.85688","DOIUrl":"https://doi.org/10.4274/tod.galenos.2020.85688","url":null,"abstract":"","PeriodicalId":41797,"journal":{"name":"Turk Osteoporoz Dergisi-Turkish Journal of Osteoporosis","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81407561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-04-09DOI: 10.4274/tod.galenos.2021.60590
O. Yazıcı, Şenay Demir Yazıcı
{"title":"Role of FRAX in the Evaluation of Osteoporosis in Patients with Chronic Obstructive Pulmonary Disease","authors":"O. Yazıcı, Şenay Demir Yazıcı","doi":"10.4274/tod.galenos.2021.60590","DOIUrl":"https://doi.org/10.4274/tod.galenos.2021.60590","url":null,"abstract":"","PeriodicalId":41797,"journal":{"name":"Turk Osteoporoz Dergisi-Turkish Journal of Osteoporosis","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2021-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74803809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-01DOI: 10.4274/tod.galenos.2020.49379
A. H. Akgülle, F. Yücel, Evrim Karadağ Saygı
Objective: The aim of this study is to investigate the frequency of fractures and related factors in children with spina bifida who were followed up in our hospital. Materials and Methods: By retrospectively examination of the medical records of 450 patients with spina bifida, who were followed up by our clinic between 2000 and 2018, the patients were evaluated in terms of factors such as frequency of fracture, age of the first fracture, lesion level, ambulation capacity, physical therapy initiation age, fracture site and mechanism. Results: In the 450 patients examined, the fracture rate was 5.7%. While there was a relationship between low ambulatory capacity and high-level lesions and fracture risk, the early initiation of physical therapy did not protect against fracture. Conclusion: According to these data, fractures are more common in patients with spina bifida. It was concluded that the quality of mobilisation, not the duration, was the more important risk factor for fracture.
{"title":"Fractures in Children with Spina Bifida","authors":"A. H. Akgülle, F. Yücel, Evrim Karadağ Saygı","doi":"10.4274/tod.galenos.2020.49379","DOIUrl":"https://doi.org/10.4274/tod.galenos.2020.49379","url":null,"abstract":"Objective: The aim of this study is to investigate the frequency of fractures and related factors in children with spina bifida who were followed up in our hospital. Materials and Methods: By retrospectively examination of the medical records of 450 patients with spina bifida, who were followed up by our clinic between 2000 and 2018, the patients were evaluated in terms of factors such as frequency of fracture, age of the first fracture, lesion level, ambulation capacity, physical therapy initiation age, fracture site and mechanism. Results: In the 450 patients examined, the fracture rate was 5.7%. While there was a relationship between low ambulatory capacity and high-level lesions and fracture risk, the early initiation of physical therapy did not protect against fracture. Conclusion: According to these data, fractures are more common in patients with spina bifida. It was concluded that the quality of mobilisation, not the duration, was the more important risk factor for fracture.","PeriodicalId":41797,"journal":{"name":"Turk Osteoporoz Dergisi-Turkish Journal of Osteoporosis","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80771388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-01DOI: 10.4274/tod.galenos.2020.37233
N. Alayunt, Osman Özüdoğru
{"title":"Changes in Vitamin D Levels According to Age, Gender and Season in the Siirt Province","authors":"N. Alayunt, Osman Özüdoğru","doi":"10.4274/tod.galenos.2020.37233","DOIUrl":"https://doi.org/10.4274/tod.galenos.2020.37233","url":null,"abstract":"","PeriodicalId":41797,"journal":{"name":"Turk Osteoporoz Dergisi-Turkish Journal of Osteoporosis","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90981703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-01DOI: 10.4274/tod.galenos.2020.36002
N. N. Mulyaningsih, A. Juwono, D. Soejoko, D. Astuti
Amaç: Osteoporoz tüm yaşlardaki kadın ve erkek bireyleri etkileyebilir. Bu çalışmanın amacı ovariektomi (OVX) proksimal kortikal epifiz kemiğinin morfolojisini, ovariektomize edilmiş sıçan modellerinde taramalı elektron mikroskobu (SEM) ve transmisyon elektron mikroskobu (TEM) kullanarak analiz etmektir. Gereç ve Yöntem: Analiz edilen kemikler ovariektomize Rattus norvegicus dişi sıçanlardan alınan kortikal femur kemikleriydi. OVX’in beşinci, yedinci ve dokuzuncu haftada devam etmesinden bu yana üçüncü haftadan itibaren karakterizasyon yapıldı. Analiz, TEM yapısından elde edilen kemik çukurunun ve nanoyapı seviyesinin şeklini ve yoğunluğunu analiz etmek için SEM görüntülerinden elde edilen 100 μm büyütmeli mikroyapı seviyesi olan iki yapı seviyesine odaklanıyordu TEM görüntülerinden elde edilen 50 nm’lik bir büyütme ile nanoyapı seviyesinin analiz edilmesi kemik analizi apatit kristalleri. Bulgular: Mikroyapı düzeyinde, OVX’ten bu yana 9 haftalık sıçanlarda ortaya çıkan boşluğun kontrol grubuna (OVX olmayan) kıyasla %68,9 arttığı tespit edildi. Nanoyapı düzeyinde, plaka, tablet ve örtüşen apatit kristallerinin hem OVX olmayan hem de OVX sıçanlarında mevcut olduğu anlaşılmaktadır. Bununla birlikte, ovariektomize edilmiş sıçanlar grubunda, apatit kristallerinin tablet boyutunun düşme eğilimi vardı. Sonuç: Rattus norvegicus beyaz sıçanlarının dişileri OVX’ten bu yana 9. haftada morfolojiye ve oyukların yüzdesine dayanan osteoporoz koşulları göstermiştir. OVX ayrıca apatit kristallerinin boyutunu da düşürdü. Anahtar kelimeler: Osteoporoz, overiektomi, kemik morfolojisi, kemik boşluğu, kemik apatit kristalleri Morphology of Proximal Cortical Epiphysis Bone of Ovariectomized Rattus Norvegicus
{"title":"Morphology of Proximal Cortical Epiphysis Bone of Ovariectomized Rattus Norvegicus","authors":"N. N. Mulyaningsih, A. Juwono, D. Soejoko, D. Astuti","doi":"10.4274/tod.galenos.2020.36002","DOIUrl":"https://doi.org/10.4274/tod.galenos.2020.36002","url":null,"abstract":"Amaç: Osteoporoz tüm yaşlardaki kadın ve erkek bireyleri etkileyebilir. Bu çalışmanın amacı ovariektomi (OVX) proksimal kortikal epifiz kemiğinin morfolojisini, ovariektomize edilmiş sıçan modellerinde taramalı elektron mikroskobu (SEM) ve transmisyon elektron mikroskobu (TEM) kullanarak analiz etmektir. Gereç ve Yöntem: Analiz edilen kemikler ovariektomize Rattus norvegicus dişi sıçanlardan alınan kortikal femur kemikleriydi. OVX’in beşinci, yedinci ve dokuzuncu haftada devam etmesinden bu yana üçüncü haftadan itibaren karakterizasyon yapıldı. Analiz, TEM yapısından elde edilen kemik çukurunun ve nanoyapı seviyesinin şeklini ve yoğunluğunu analiz etmek için SEM görüntülerinden elde edilen 100 μm büyütmeli mikroyapı seviyesi olan iki yapı seviyesine odaklanıyordu TEM görüntülerinden elde edilen 50 nm’lik bir büyütme ile nanoyapı seviyesinin analiz edilmesi kemik analizi apatit kristalleri. Bulgular: Mikroyapı düzeyinde, OVX’ten bu yana 9 haftalık sıçanlarda ortaya çıkan boşluğun kontrol grubuna (OVX olmayan) kıyasla %68,9 arttığı tespit edildi. Nanoyapı düzeyinde, plaka, tablet ve örtüşen apatit kristallerinin hem OVX olmayan hem de OVX sıçanlarında mevcut olduğu anlaşılmaktadır. Bununla birlikte, ovariektomize edilmiş sıçanlar grubunda, apatit kristallerinin tablet boyutunun düşme eğilimi vardı. Sonuç: Rattus norvegicus beyaz sıçanlarının dişileri OVX’ten bu yana 9. haftada morfolojiye ve oyukların yüzdesine dayanan osteoporoz koşulları göstermiştir. OVX ayrıca apatit kristallerinin boyutunu da düşürdü. Anahtar kelimeler: Osteoporoz, overiektomi, kemik morfolojisi, kemik boşluğu, kemik apatit kristalleri Morphology of Proximal Cortical Epiphysis Bone of Ovariectomized Rattus Norvegicus","PeriodicalId":41797,"journal":{"name":"Turk Osteoporoz Dergisi-Turkish Journal of Osteoporosis","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83706768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-08-28DOI: 10.4274/tod.galenos.2020.65477
Y. Kutsal, O. Özdemir, M. Sarıdoğan, Z. Günendi, A. Küçükdeveci, Y. Kirazlı, J. Meray
Osteosarcopenia is a geriatric syndrome characterised by the co-existence of osteoporosis and sarcopenia, two chronic musculoskeletal conditions associated with ageing. This syndrome may lead to falls and fractures, increased morbidity, mortality and disability, and reduced quality of life. The etiopathogenesis of osteosarcopenia is multifactorial; mechanical, biochemical, genetic and lifestyle factors all play important roles. Its prevalence has been reported between 5% and 37%. The varied prevalence is likely due to the heterogeneous populations or non-unified diagnostic criteria for this syndrome. Osteosarcopenia can be diagnosed by detailed clinical assessment (e.g. screening and risk calculation tools, grip strength, physical performance tests), laboratory tests and imaging methods. Dual-energy X-ray absorptiometry is the most common method used in measuring bone mineral density for the diagnosis of osteoporosis. The imaging techniques used to detect loss of skeletal muscle mass in sarcopenia are dual-energy X-ray absorptiometry, computed tomography, ultrasonography and magnetic resonance imaging. Treatment options for osteosarcopenia include exercise, nutritional supplements (protein, vitamin D, calcium and creatine), life style modifications and pharmacological therapy. With increasing understanding of the underlying mechanisms of osteosarcopenia, the development of therapeutic agents targeting both muscle and bone has become a new area of investigation. This review summarises the epidemiology, pathophysiology, diagnosis and treatment of osteosarcopenia in the light of the relevant literature.
{"title":"Osteosarcopenia: Clinical Perspective","authors":"Y. Kutsal, O. Özdemir, M. Sarıdoğan, Z. Günendi, A. Küçükdeveci, Y. Kirazlı, J. Meray","doi":"10.4274/tod.galenos.2020.65477","DOIUrl":"https://doi.org/10.4274/tod.galenos.2020.65477","url":null,"abstract":"Osteosarcopenia is a geriatric syndrome characterised by the co-existence of osteoporosis and sarcopenia, two chronic musculoskeletal conditions associated with ageing. This syndrome may lead to falls and fractures, increased morbidity, mortality and disability, and reduced quality of life. The etiopathogenesis of osteosarcopenia is multifactorial; mechanical, biochemical, genetic and lifestyle factors all play important roles. Its prevalence has been reported between 5% and 37%. The varied prevalence is likely due to the heterogeneous populations or non-unified diagnostic criteria for this syndrome. Osteosarcopenia can be diagnosed by detailed clinical assessment (e.g. screening and risk calculation tools, grip strength, physical performance tests), laboratory tests and imaging methods. Dual-energy X-ray absorptiometry is the most common method used in measuring bone mineral density for the diagnosis of osteoporosis. The imaging techniques used to detect loss of skeletal muscle mass in sarcopenia are dual-energy X-ray absorptiometry, computed tomography, ultrasonography and magnetic resonance imaging. Treatment options for osteosarcopenia include exercise, nutritional supplements (protein, vitamin D, calcium and creatine), life style modifications and pharmacological therapy. With increasing understanding of the underlying mechanisms of osteosarcopenia, the development of therapeutic agents targeting both muscle and bone has become a new area of investigation. This review summarises the epidemiology, pathophysiology, diagnosis and treatment of osteosarcopenia in the light of the relevant literature.","PeriodicalId":41797,"journal":{"name":"Turk Osteoporoz Dergisi-Turkish Journal of Osteoporosis","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2020-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84449362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-08-28DOI: 10.4274/tod.galenos.2020.98700
Aslı Çalışkan Arıcan, Y. Kutsal, N. P. Acar, F. Akbıyık, S. Karahan, R. Karabudak
{"title":"Factors Affecting Bone Mineral Density in Male Patients with Primary Progressive Multiple Sclerosis","authors":"Aslı Çalışkan Arıcan, Y. Kutsal, N. P. Acar, F. Akbıyık, S. Karahan, R. Karabudak","doi":"10.4274/tod.galenos.2020.98700","DOIUrl":"https://doi.org/10.4274/tod.galenos.2020.98700","url":null,"abstract":"","PeriodicalId":41797,"journal":{"name":"Turk Osteoporoz Dergisi-Turkish Journal of Osteoporosis","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2020-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74719606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-08-28DOI: 10.4274/tod.galenos.2020.05657
H. Sucuoğlu, A. Aktürk
Sacral stress fractures (SSF) are one of the rare causes of lumbar and hip pain during pregnancy. The purpose of this report is to present a case of SSF diagnosed in the second trimester of pregnancy along with its diagnosis and treatment as wells as the type of birth. A 27-year-old primigravid patient presented with lumbar and hip pain at 25 weeks of gestation. Magnetic resonance imaging revealed SSF. The patient was followed up with conservative treatment. She gave birth by caesarean section at 38 weeks of gestation. Bone mineral density analysis revealed pregnancy-related osteoporosis in the postpartum period. Two months later, the patient’s symptoms were completely resolved. SSF should be considered in the differential diagnosis of lumbar and hip pain during pregnancy, and it should be kept in mind that these fractures may also occur in the prepartum period. Pregnancy-related osteoporosis is a risk factor for SSF. Caesarean section can be recommended as the type of birth in the women with SSF while considering the possible displacement risk for the fracture. to the best of our knowledge, only three cases are reported during the prepartum period (1,4,8). SSF diagnosis can be delayed due to its rarity and unknown etiology and is included in the differential diagnosis of lumbar and hip pain in pregnant women. It is diagnosed via a vertical fracture line in the sacrum and edema in the surrounding bone as revealed by magnetic resonance imaging (MRI) (4,9). Difficulties may be experienced in prepartum SSF treatment due to pregnancy; the question of which type of birth should be performed in these patients remains controversial (1,4). Herein, we present a case of prepartum SSF and discuss these patients with their treatment and type of birth. Abstract
{"title":"Sacral Stress Fracture in Pregnancy: Case Report and Review of Literature","authors":"H. Sucuoğlu, A. Aktürk","doi":"10.4274/tod.galenos.2020.05657","DOIUrl":"https://doi.org/10.4274/tod.galenos.2020.05657","url":null,"abstract":"Sacral stress fractures (SSF) are one of the rare causes of lumbar and hip pain during pregnancy. The purpose of this report is to present a case of SSF diagnosed in the second trimester of pregnancy along with its diagnosis and treatment as wells as the type of birth. A 27-year-old primigravid patient presented with lumbar and hip pain at 25 weeks of gestation. Magnetic resonance imaging revealed SSF. The patient was followed up with conservative treatment. She gave birth by caesarean section at 38 weeks of gestation. Bone mineral density analysis revealed pregnancy-related osteoporosis in the postpartum period. Two months later, the patient’s symptoms were completely resolved. SSF should be considered in the differential diagnosis of lumbar and hip pain during pregnancy, and it should be kept in mind that these fractures may also occur in the prepartum period. Pregnancy-related osteoporosis is a risk factor for SSF. Caesarean section can be recommended as the type of birth in the women with SSF while considering the possible displacement risk for the fracture. to the best of our knowledge, only three cases are reported during the prepartum period (1,4,8). SSF diagnosis can be delayed due to its rarity and unknown etiology and is included in the differential diagnosis of lumbar and hip pain in pregnant women. It is diagnosed via a vertical fracture line in the sacrum and edema in the surrounding bone as revealed by magnetic resonance imaging (MRI) (4,9). Difficulties may be experienced in prepartum SSF treatment due to pregnancy; the question of which type of birth should be performed in these patients remains controversial (1,4). Herein, we present a case of prepartum SSF and discuss these patients with their treatment and type of birth. Abstract","PeriodicalId":41797,"journal":{"name":"Turk Osteoporoz Dergisi-Turkish Journal of Osteoporosis","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2020-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75049539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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