Pub Date : 2022-09-04DOI: 10.1183/13993003.congress-2022.662
M. Nakayama, H. Ishigaki, N. Thanh Cong, S. Suzuki, H. Ishida, N. Kitagawa, K. Ogasawara, Y. Itoh
{"title":"Long-term efficacy of an inactivated whole particle H5N1 virus against H5N1 highly pathogenic avian influenza virus challenge in cynomolgus monkeys","authors":"M. Nakayama, H. Ishigaki, N. Thanh Cong, S. Suzuki, H. Ishida, N. Kitagawa, K. Ogasawara, Y. Itoh","doi":"10.1183/13993003.congress-2022.662","DOIUrl":"https://doi.org/10.1183/13993003.congress-2022.662","url":null,"abstract":"","PeriodicalId":420846,"journal":{"name":"10.01 - Respiratory infections and bronchiectasis","volume":"241 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133491498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-04DOI: 10.1183/13993003.congress-2022.257
J. Davy, P. Tang, M. Burton
{"title":"Ambulatory management of bronchopleural fistulae secondary to empyema","authors":"J. Davy, P. Tang, M. Burton","doi":"10.1183/13993003.congress-2022.257","DOIUrl":"https://doi.org/10.1183/13993003.congress-2022.257","url":null,"abstract":"","PeriodicalId":420846,"journal":{"name":"10.01 - Respiratory infections and bronchiectasis","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133639379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-04DOI: 10.1183/13993003.congress-2022.332
M. Hassan, M. Gadallah, A. Elshazly, B. El-shaarawy, A. Sadaka
{"title":"The microbiology of adult pleural infection in an Egyptian hospital","authors":"M. Hassan, M. Gadallah, A. Elshazly, B. El-shaarawy, A. Sadaka","doi":"10.1183/13993003.congress-2022.332","DOIUrl":"https://doi.org/10.1183/13993003.congress-2022.332","url":null,"abstract":"","PeriodicalId":420846,"journal":{"name":"10.01 - Respiratory infections and bronchiectasis","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132106944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-04DOI: 10.1183/13993003.congress-2022.3312
C. Lythgoe, A. Rowe, O. Aiyegbusi, L. Chambers, F. Sherratt, J. Wood, B. Young, D. Wootton
Background: Patient reported outcome measures (PROMs) provide a standardised method to capture patient perspectives which can be used in comparative effectiveness research to inform the evaluation of treatment. Thus far, PROMs have focussed on the long-term sequelae of COVID-19 rather than the acute illness and initial recovery period. Aim(s): To design a psychometrically validated COVID-19 specific PROM to be used in the acute and recovery phase of illness. Method(s): A review of existing literature, evaluation of existing PROMs, input from local experts (n=15) and in-depth qualitative concept elicitation interviews with patients (n=8) were used to create a conceptual framework which informed the generation of items included in the PROM. Cognitive interviews with patients (n=8) were then used to develop and refine the items for inclusion in the PROM and confirm the content and face validity of the draft tool. A nominal group meeting of the expert panel (n=6) was held to confirm the final items for inclusion. Result(s): The CoV-Sym PROM consists of 19 domains and 44 items which are scored using a five-point Likert scale to enable objective measurement of patients' symptomatic recovery from acute COVID-19 illness. Questions address physical, psychological and social domains. Cognitive interviews revealed acceptable content and face validity. Conclusion(s): With the involvement of both patients and experts in the development and validation process, we have created the first COVID-19 specific PROM to measure patient's symptomatic recovery from acute COVID-19 infection. It is ready for further psychometric testing to confirm reliability and responsiveness, the results of which will be presented.
{"title":"CoV-Sym: The development of a psychometrically validated patient reported outcome measure for COVID-19","authors":"C. Lythgoe, A. Rowe, O. Aiyegbusi, L. Chambers, F. Sherratt, J. Wood, B. Young, D. Wootton","doi":"10.1183/13993003.congress-2022.3312","DOIUrl":"https://doi.org/10.1183/13993003.congress-2022.3312","url":null,"abstract":"Background: Patient reported outcome measures (PROMs) provide a standardised method to capture patient perspectives which can be used in comparative effectiveness research to inform the evaluation of treatment. Thus far, PROMs have focussed on the long-term sequelae of COVID-19 rather than the acute illness and initial recovery period. Aim(s): To design a psychometrically validated COVID-19 specific PROM to be used in the acute and recovery phase of illness. Method(s): A review of existing literature, evaluation of existing PROMs, input from local experts (n=15) and in-depth qualitative concept elicitation interviews with patients (n=8) were used to create a conceptual framework which informed the generation of items included in the PROM. Cognitive interviews with patients (n=8) were then used to develop and refine the items for inclusion in the PROM and confirm the content and face validity of the draft tool. A nominal group meeting of the expert panel (n=6) was held to confirm the final items for inclusion. Result(s): The CoV-Sym PROM consists of 19 domains and 44 items which are scored using a five-point Likert scale to enable objective measurement of patients' symptomatic recovery from acute COVID-19 illness. Questions address physical, psychological and social domains. Cognitive interviews revealed acceptable content and face validity. Conclusion(s): With the involvement of both patients and experts in the development and validation process, we have created the first COVID-19 specific PROM to measure patient's symptomatic recovery from acute COVID-19 infection. It is ready for further psychometric testing to confirm reliability and responsiveness, the results of which will be presented.","PeriodicalId":420846,"journal":{"name":"10.01 - Respiratory infections and bronchiectasis","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133029774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-04DOI: 10.1183/13993003.congress-2022.1318
I. Ketata, S. Majdoub Fehri, W. Madi, R. Sellami, H. Kwass
{"title":"what relationship between eosinophilia and covid19 prognosis?","authors":"I. Ketata, S. Majdoub Fehri, W. Madi, R. Sellami, H. Kwass","doi":"10.1183/13993003.congress-2022.1318","DOIUrl":"https://doi.org/10.1183/13993003.congress-2022.1318","url":null,"abstract":"","PeriodicalId":420846,"journal":{"name":"10.01 - Respiratory infections and bronchiectasis","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133553694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-04DOI: 10.1183/13993003.congress-2022.2784
G. Canelas, M. Gomes, C. Nuñes Silva, A. Sarmento, M. Tavares
{"title":"Developing a Long-COVID follow-up protocol in a Portuguese tertiary hospital","authors":"G. Canelas, M. Gomes, C. Nuñes Silva, A. Sarmento, M. Tavares","doi":"10.1183/13993003.congress-2022.2784","DOIUrl":"https://doi.org/10.1183/13993003.congress-2022.2784","url":null,"abstract":"","PeriodicalId":420846,"journal":{"name":"10.01 - Respiratory infections and bronchiectasis","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133558538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-04DOI: 10.1183/13993003.congress-2022.3902
I. Kharrat, A. Kacem, H. Hannechi, R. Benjazia, H. Zorgati, S. Mefteh, D. Benbraiek, J. Ayachi, A. Maatalla, L. Merzougui
{"title":"The charateristics of patients with pulmonary post covid fibrosis","authors":"I. Kharrat, A. Kacem, H. Hannechi, R. Benjazia, H. Zorgati, S. Mefteh, D. Benbraiek, J. Ayachi, A. Maatalla, L. Merzougui","doi":"10.1183/13993003.congress-2022.3902","DOIUrl":"https://doi.org/10.1183/13993003.congress-2022.3902","url":null,"abstract":"","PeriodicalId":420846,"journal":{"name":"10.01 - Respiratory infections and bronchiectasis","volume":"78 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123127827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-04DOI: 10.1183/13993003.congress-2022.2067
T. Hinks, M. Brown, S. Morgan, G. Donachie, I. Pavord, C. Arancibia
{"title":"Non-typeable Haemophilus influenzae activates respiratory epithelial cell innate immune responses independently of intracellular internalisation","authors":"T. Hinks, M. Brown, S. Morgan, G. Donachie, I. Pavord, C. Arancibia","doi":"10.1183/13993003.congress-2022.2067","DOIUrl":"https://doi.org/10.1183/13993003.congress-2022.2067","url":null,"abstract":"","PeriodicalId":420846,"journal":{"name":"10.01 - Respiratory infections and bronchiectasis","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132626699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-04DOI: 10.1183/13993003.congress-2022.2998
H. Keir, H. Richardson, A. Veluchamy, D. Alferes De Lima, A. Gilmour, C. Hennayake, A. Dicker, M. Crichton, J. Chalmers
{"title":"Molecular characterisation of COPD exacerbations","authors":"H. Keir, H. Richardson, A. Veluchamy, D. Alferes De Lima, A. Gilmour, C. Hennayake, A. Dicker, M. Crichton, J. Chalmers","doi":"10.1183/13993003.congress-2022.2998","DOIUrl":"https://doi.org/10.1183/13993003.congress-2022.2998","url":null,"abstract":"","PeriodicalId":420846,"journal":{"name":"10.01 - Respiratory infections and bronchiectasis","volume":"158 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121249838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-04DOI: 10.1183/13993003.congress-2022.3036
D. Schumann, A. Hoheisel, K. Jahn, N. Khanna, M. Herrmann, A. Darie, S. Ragozzino, S. Kuster, W. Strobel, H. Hirsch, M. Tamm, D. Stolz
{"title":"Host transcriptomic signature for infection in patients with suspicion of LRTI undergoing bronchoscopy","authors":"D. Schumann, A. Hoheisel, K. Jahn, N. Khanna, M. Herrmann, A. Darie, S. Ragozzino, S. Kuster, W. Strobel, H. Hirsch, M. Tamm, D. Stolz","doi":"10.1183/13993003.congress-2022.3036","DOIUrl":"https://doi.org/10.1183/13993003.congress-2022.3036","url":null,"abstract":"","PeriodicalId":420846,"journal":{"name":"10.01 - Respiratory infections and bronchiectasis","volume":"148 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115969867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}