Pub Date : 1900-01-01DOI: 10.59717/j.xinn-med.2023.100005
A. Wong
{"title":"Pushing the boundary of cancer diagnostics through microfluidic technologies","authors":"A. Wong","doi":"10.59717/j.xinn-med.2023.100005","DOIUrl":"https://doi.org/10.59717/j.xinn-med.2023.100005","url":null,"abstract":"","PeriodicalId":423184,"journal":{"name":"The Innovation Medicine","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124939746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a crucial curative method to treat hematologic malignancies and non-malignant hematologic disorder. 1,
同种异体造血干细胞移植是治疗恶性血液病和非恶性血液病的重要方法。1，
{"title":"Basiliximab is the potential solution for severe liver chronic GVHD: A prospective pilot study","authors":"Dao-Xing Deng, Mengzhu Shen, Xiaohui Zhang, Lanping Xu, Yu Wang, Chen‐hua Yan, Yuhong Chen, Huan Chen, W. Han, Feng‐rong Wang, Jing‐zhi Wang, Xiaojun Huang, X. Mo","doi":"10.59717/j.xinn-med.2023.100009","DOIUrl":"https://doi.org/10.59717/j.xinn-med.2023.100009","url":null,"abstract":"Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a crucial curative method to treat hematologic malignancies and non-malignant hematologic disorder. 1,","PeriodicalId":423184,"journal":{"name":"The Innovation Medicine","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117047455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.59717/j.xinn-med.2023.100024
Shuang Zhou, R. Xu, Gongbo Chen, P. Yu, Yuming Guo
{"title":"Where is the boundary of wildfire smoke?","authors":"Shuang Zhou, R. Xu, Gongbo Chen, P. Yu, Yuming Guo","doi":"10.59717/j.xinn-med.2023.100024","DOIUrl":"https://doi.org/10.59717/j.xinn-med.2023.100024","url":null,"abstract":"","PeriodicalId":423184,"journal":{"name":"The Innovation Medicine","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124864217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.59717/j.xinn-med.2023.100022
Xueyang Zhang, Jiuyang Xu, Ye-ming Wang, Hui Li, Jiapei Yu, Xiaoyu Shang, L. Shang, B. Hou, Xulong Zhang, Bin Cao
The susceptibility of the elderly to respiratory viral infections and the challenges posed by an aging population necessitate imperative development of advanced preventive and therapeutic strategies for elderly individuals. The clinical outcome of such infections is intricately determined by the complex interplay among viruses, host tissues, and immune cells. Elderly individuals exhibit a diminished efficacy of their immune system to clear viruses, consequently leading to prolonged viral insults, tissue damage, and an excessive activation of inflammatory cells. These ultimately result in worse clinical outcomes. Targeting the dysregulated antiviral immune responses has emerged as a potential approach to improve the prognosis of geriatric patients. It is noteworthy that the impacts of aging on antiviral immune responses are highly heterogenous. Thus, individualized patient assessment and management assume paramount importance. This review aims to summarize the current evidence elucidating the effects of aging on immune responses to respiratory viruses, with the ultimate goal of identifying knowledge gaps that can inform future research and enhance the management of elderly individuals.
{"title":"Respiratory viral infections in the elderly: From the perspective of the aging immune system","authors":"Xueyang Zhang, Jiuyang Xu, Ye-ming Wang, Hui Li, Jiapei Yu, Xiaoyu Shang, L. Shang, B. Hou, Xulong Zhang, Bin Cao","doi":"10.59717/j.xinn-med.2023.100022","DOIUrl":"https://doi.org/10.59717/j.xinn-med.2023.100022","url":null,"abstract":"The susceptibility of the elderly to respiratory viral infections and the challenges posed by an aging population necessitate imperative development of advanced preventive and therapeutic strategies for elderly individuals. The clinical outcome of such infections is intricately determined by the complex interplay among viruses, host tissues, and immune cells. Elderly individuals exhibit a diminished efficacy of their immune system to clear viruses, consequently leading to prolonged viral insults, tissue damage, and an excessive activation of inflammatory cells. These ultimately result in worse clinical outcomes. Targeting the dysregulated antiviral immune responses has emerged as a potential approach to improve the prognosis of geriatric patients. It is noteworthy that the impacts of aging on antiviral immune responses are highly heterogenous. Thus, individualized patient assessment and management assume paramount importance. This review aims to summarize the current evidence elucidating the effects of aging on immune responses to respiratory viruses, with the ultimate goal of identifying knowledge gaps that can inform future research and enhance the management of elderly individuals.\u0000","PeriodicalId":423184,"journal":{"name":"The Innovation Medicine","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127082722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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