{"title":"Restless Legs Syndrome, Sleep Quality and Fatigue in Hemodialysis Patients","authors":"G. Turgay, E. Tutal, S. Sezer","doi":"10.5262/tndt.2018.3095","DOIUrl":"https://doi.org/10.5262/tndt.2018.3095","url":null,"abstract":"","PeriodicalId":42328,"journal":{"name":"Turkish Nephrology Dialysis and Transplantation Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41350113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ilter Bozaci, Tugay Avcı, Sevil Nalbant, İbrahim Vasi, Mehmet Soydan
{"title":"Oral D Vitamin Replasmanına Bağlı Gelişen Hiperkalsemi ve Akut Böbrek Hasarı","authors":"Ilter Bozaci, Tugay Avcı, Sevil Nalbant, İbrahim Vasi, Mehmet Soydan","doi":"10.5262/TNDT.2018.2827","DOIUrl":"https://doi.org/10.5262/TNDT.2018.2827","url":null,"abstract":"","PeriodicalId":42328,"journal":{"name":"Turkish Nephrology Dialysis and Transplantation Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46949531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Murside Esra Dolarslan, S. Bardak, K. Turgutalp, S. Demir, A. Kiykim
{"title":"A Rare Cause of Hyponatremia and Acute Kidney Injury: Leptospirosis","authors":"Murside Esra Dolarslan, S. Bardak, K. Turgutalp, S. Demir, A. Kiykim","doi":"10.5262/TNDT.2018.2823","DOIUrl":"https://doi.org/10.5262/TNDT.2018.2823","url":null,"abstract":"","PeriodicalId":42328,"journal":{"name":"Turkish Nephrology Dialysis and Transplantation Journal","volume":"27 1","pages":"218-220"},"PeriodicalIF":0.0,"publicationDate":"2018-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45251766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Abedi, E. Eroglu, I. Kocyiğit, A. Unal, M. Sipahioğlu, B. Tokgoz, O. Oymak
Familial Mediterranean fever (FMF) is an autosomal recessive hereditary disease characterized by recurrent attacks of fever, usually accompanied by sterile polyserositis. Although colchicine is the main medical treatment option for FMF, potential adverse effects and drug interactions should be considered during the follow-up of these patients. Herein, we presented a case of a hemodialysis patient with FMF, who developed rhabdomyolysis due to concomitant use of colchicine and clarithromycin for pneumonia treatment.
{"title":"Colchicine and Clarithromycin Induced Rhabdomyolysis in a Hemodialysis Patient with Familial Mediterranean Fever","authors":"A. Abedi, E. Eroglu, I. Kocyiğit, A. Unal, M. Sipahioğlu, B. Tokgoz, O. Oymak","doi":"10.5262/TNDT.2018.2976","DOIUrl":"https://doi.org/10.5262/TNDT.2018.2976","url":null,"abstract":"Familial Mediterranean fever (FMF) is an autosomal recessive hereditary disease characterized by recurrent attacks of fever, usually accompanied by sterile polyserositis. Although colchicine is the main medical treatment option for FMF, potential adverse effects and drug interactions should be considered during the follow-up of these patients. Herein, we presented a case of a hemodialysis patient with FMF, who developed rhabdomyolysis due to concomitant use of colchicine and clarithromycin for pneumonia treatment.","PeriodicalId":42328,"journal":{"name":"Turkish Nephrology Dialysis and Transplantation Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42901072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Yıldız, M. Seferoğlu, A. Güneş, Nilufer Buyukkoyuncu, A. Yildiz, K. Kılıc, C. Gül, S. Kahvecioğlu, A. Oruc, D. Sığırlı
OBJECTIVE: Our aim was to assess cognitive dysfunction, which is common in hemodialysis patients and difficult to diagnose, by an easily applicable test, the Mini Mental State Examination and Clock Drawing Test. MATERIAL and METHODS: Two hundred and sixty six (266, 88.37%) dialysis patients that were followed-up at the Nephrology Clinic of Bursa Specialty Training and Research Hospital and private dialysis centers, and 35 (11.63%) healthy control individuals were involved in our study. Mini Mental State Examination and Clock Drawing Test were applied by a neurologist to the subjects. MMSE and CDT scores of the patients were compared with the control group. RESULTS: Patient and control groups were similar in terms of age, gender, diabetes, and smoking. The rate of hypertension was significantly higher in the dialysis group. Mini Mental State Examination and Clock Drawing Test success rates were significantly higher in the control group. Orientation, attention and language modalities evaluated in the MMSE were observed to be significantly lower in the hemodialysis group. A statistically significant inverse correlation was found between registration memory and recall scores in MMSE, and urea. CONCLUSION: Cognitive performances of hemodialysis patients must be monitored closely. The relationship between record memory and recall scores and urea suggests that uremic toxins may affect memory functions negatively. In addition, cognitive performance can be monitored by Clock Drawing Test in these patients.
{"title":"Assessment of Cognitive Dysfunction in Hemodialysis Patients By the Mini Mental Test and the Clock Drawing Test","authors":"D. Yıldız, M. Seferoğlu, A. Güneş, Nilufer Buyukkoyuncu, A. Yildiz, K. Kılıc, C. Gül, S. Kahvecioğlu, A. Oruc, D. Sığırlı","doi":"10.5262/tndt.2018.3201","DOIUrl":"https://doi.org/10.5262/tndt.2018.3201","url":null,"abstract":"OBJECTIVE: Our aim was to assess cognitive dysfunction, which is common in hemodialysis patients and difficult to diagnose, by an easily applicable test, the Mini Mental State Examination and Clock Drawing Test. MATERIAL and METHODS: Two hundred and sixty six (266, 88.37%) dialysis patients that were followed-up at the Nephrology Clinic of Bursa Specialty Training and Research Hospital and private dialysis centers, and 35 (11.63%) healthy control individuals were involved in our study. Mini Mental State Examination and Clock Drawing Test were applied by a neurologist to the subjects. MMSE and CDT scores of the patients were compared with the control group. RESULTS: Patient and control groups were similar in terms of age, gender, diabetes, and smoking. The rate of hypertension was significantly higher in the dialysis group. Mini Mental State Examination and Clock Drawing Test success rates were significantly higher in the control group. Orientation, attention and language modalities evaluated in the MMSE were observed to be significantly lower in the hemodialysis group. A statistically significant inverse correlation was found between registration memory and recall scores in MMSE, and urea. CONCLUSION: Cognitive performances of hemodialysis patients must be monitored closely. The relationship between record memory and recall scores and urea suggests that uremic toxins may affect memory functions negatively. In addition, cognitive performance can be monitored by Clock Drawing Test in these patients.","PeriodicalId":42328,"journal":{"name":"Turkish Nephrology Dialysis and Transplantation Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44850301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-19DOI: 10.5262/tndt.2018.1001.05
I. Dogan, Şakir Altuner, S. Kahvecioğlu, Ahmet Hunuk, B. Eser, O. Yayar, Ünal Kurtoğlu, H. Bayol
{"title":"Relationship of Serum Asymmetric Dimethylarginine Levels with Inflammation and Cardiac Functions in Autosomal Dominant Polycystic Kidney Disease","authors":"I. Dogan, Şakir Altuner, S. Kahvecioğlu, Ahmet Hunuk, B. Eser, O. Yayar, Ünal Kurtoğlu, H. Bayol","doi":"10.5262/tndt.2018.1001.05","DOIUrl":"https://doi.org/10.5262/tndt.2018.1001.05","url":null,"abstract":"","PeriodicalId":42328,"journal":{"name":"Turkish Nephrology Dialysis and Transplantation Journal","volume":"27 1","pages":"68-75"},"PeriodicalIF":0.0,"publicationDate":"2018-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48473241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-19DOI: 10.5262/tndt.2018.1001.04
H. Tonbul, L. Altıntepe, I. Baloglu
OBJECTIVE: Anemia is a common problem in chronic renal failure. Recent studies have shown that there is a close relationship between fluctuations in hemoglobin values and increased mortality. Therefore, treatment of anemia and providing stable hemoglobin (Hb) levels with erythropoiesisstimulating agent (ESA) is important in the management of chronic renal failure. Hence, ESA usage and relationship between ESA type and Hb variability were investigated in hemodialysis patients. MATERIAL and METHODS: 130 patients treated at a hemodialysis center were monitored monthly for one year. The mean age was 60±7 years, mean weight was 72±13 kg, and mean dialysis duration was 5 ±2 years (F/M: 64/66). Hb stability was defined as continuous ESA usage at maintenance dosage and Hb levels being at the target level (Hb≥11g/dl) for last 12 months. Hb variability and ESA dose change was accepted as decrease of Hb levels under 11 g/dl during maintenance dosage use and increasing ESA to starting dosage. In our study, annual mean values of monthly prescribed ESA rates, types of ESA and weekly dosages, and changes in ESA dosages due to monthly changes in hemoglobin (Hb) levels were examined. The relation between ESA type and Hb variability was investigated. RESULTS: During a one-year period, the number of patients who did not use ESA (Hb levels always >12 g/dl) was 5 (%3.8) and the number of patients who used ESA for different periods was 125 (%96.2). The mean number of patients using ESA monthly was 71 (57%). 32 (45%) patients used short acting, 31 (44%) used medium acting (darbepoetin) and 8 (11%) used long acting ESA (methoxy polyethylene glycol-epoetin beta). 26 patients (21%) used ESA at the starting dose and 45 (36%) at the maintenance dose. One third of the 71 patients (36.6%) were using ESA at the starting dose and two thirds (63.4%) were on the maintenance dose. Mean weekly short acting ESA dose was 9666±2376 IU in the starting dose group and 5400±1142 IU in the maintenance group. Mean weekly darbepoetin dose was 46.6±10,3 mcg in the starting dose group and 26.4±4,9 mcg in the maintenance group. There were no Hb changes in 33 patients (26.4%) but 92 (73.6%) had Hb variability during one year. During one year, the Hb level dropped under 11 g/dl once in 32 patients (35%), twice in 39 patients (42%), three times in 16 patients (17%) and four times in 5 (6%) patients and the ESA dose was increased to the starting dose. Number of monthly Hb changes was higher in the short acting ESA than the medium and long acting ESA groups. CONCLUSION: Our results revealed that monthly ESA usage rate and weekly ESA dosage were lower than in western countries. During the one year period, there was Hb variability in three in four of the patients and ESA dosages were changed. The number of monthly Hb variability cases was found to be lower in the medium and long acting ESA groups. The most important reason of Hb variability was monthly dose change or discontinuation of ESA, due to the
{"title":"Relationship Between Erythropoiesis-Stimulating Agent Usage and Hemoglobin Variability in Hemodialysis Patients","authors":"H. Tonbul, L. Altıntepe, I. Baloglu","doi":"10.5262/tndt.2018.1001.04","DOIUrl":"https://doi.org/10.5262/tndt.2018.1001.04","url":null,"abstract":"OBJECTIVE: Anemia is a common problem in chronic renal failure. Recent studies have shown that there is a close relationship between fluctuations in hemoglobin values and increased mortality. Therefore, treatment of anemia and providing stable hemoglobin (Hb) levels with erythropoiesisstimulating agent (ESA) is important in the management of chronic renal failure. Hence, ESA usage and relationship between ESA type and Hb variability were investigated in hemodialysis patients. MATERIAL and METHODS: 130 patients treated at a hemodialysis center were monitored monthly for one year. The mean age was 60±7 years, mean weight was 72±13 kg, and mean dialysis duration was 5 ±2 years (F/M: 64/66). Hb stability was defined as continuous ESA usage at maintenance dosage and Hb levels being at the target level (Hb≥11g/dl) for last 12 months. Hb variability and ESA dose change was accepted as decrease of Hb levels under 11 g/dl during maintenance dosage use and increasing ESA to starting dosage. In our study, annual mean values of monthly prescribed ESA rates, types of ESA and weekly dosages, and changes in ESA dosages due to monthly changes in hemoglobin (Hb) levels were examined. The relation between ESA type and Hb variability was investigated. RESULTS: During a one-year period, the number of patients who did not use ESA (Hb levels always >12 g/dl) was 5 (%3.8) and the number of patients who used ESA for different periods was 125 (%96.2). The mean number of patients using ESA monthly was 71 (57%). 32 (45%) patients used short acting, 31 (44%) used medium acting (darbepoetin) and 8 (11%) used long acting ESA (methoxy polyethylene glycol-epoetin beta). 26 patients (21%) used ESA at the starting dose and 45 (36%) at the maintenance dose. One third of the 71 patients (36.6%) were using ESA at the starting dose and two thirds (63.4%) were on the maintenance dose. Mean weekly short acting ESA dose was 9666±2376 IU in the starting dose group and 5400±1142 IU in the maintenance group. Mean weekly darbepoetin dose was 46.6±10,3 mcg in the starting dose group and 26.4±4,9 mcg in the maintenance group. There were no Hb changes in 33 patients (26.4%) but 92 (73.6%) had Hb variability during one year. During one year, the Hb level dropped under 11 g/dl once in 32 patients (35%), twice in 39 patients (42%), three times in 16 patients (17%) and four times in 5 (6%) patients and the ESA dose was increased to the starting dose. Number of monthly Hb changes was higher in the short acting ESA than the medium and long acting ESA groups. CONCLUSION: Our results revealed that monthly ESA usage rate and weekly ESA dosage were lower than in western countries. During the one year period, there was Hb variability in three in four of the patients and ESA dosages were changed. The number of monthly Hb variability cases was found to be lower in the medium and long acting ESA groups. The most important reason of Hb variability was monthly dose change or discontinuation of ESA, due to the","PeriodicalId":42328,"journal":{"name":"Turkish Nephrology Dialysis and Transplantation Journal","volume":"27 1","pages":"63-67"},"PeriodicalIF":0.0,"publicationDate":"2018-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44725911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-19DOI: 10.5262/tndt.2018.1001.02
Neslihan Ülger Öztürk, Reyhan Nergiz-Unal
Chronic kidney disease can be defined as chronic and progressive deterioration of the regulation of fluid-solute balance and metabolic-endocrine functions of the kidney due to diminishing glomerular filtration. Inflammation in renal disease can develop as a cause or an outcome, and it has been reported in recent studies that inflammation is among the most important causes of disease-related mortality. Investigations on inflammation and diet interactions have shown that the effects of nutrients such as polyunsaturated fatty acids, vitamin D, vitamin E and other dietary components such as carnitine, lipoic acid, flavanoids, probiotics and prebiotics may have positive effects on the renal inflammation process. In this review, the potential anti-inflammatory effects of some current dietary components in chronic kidney disease were studied.
{"title":"Kronik Böbrek Hastalığında Renal İnflamasyon ve Bazı Güncel Diyet Bileşenleri İlişkisi","authors":"Neslihan Ülger Öztürk, Reyhan Nergiz-Unal","doi":"10.5262/tndt.2018.1001.02","DOIUrl":"https://doi.org/10.5262/tndt.2018.1001.02","url":null,"abstract":"Chronic kidney disease can be defined as chronic and progressive deterioration of the regulation of fluid-solute balance and metabolic-endocrine functions of the kidney due to diminishing glomerular filtration. Inflammation in renal disease can develop as a cause or an outcome, and it has been reported in recent studies that inflammation is among the most important causes of disease-related mortality. Investigations on inflammation and diet interactions have shown that the effects of nutrients such as polyunsaturated fatty acids, vitamin D, vitamin E and other dietary components such as carnitine, lipoic acid, flavanoids, probiotics and prebiotics may have positive effects on the renal inflammation process. In this review, the potential anti-inflammatory effects of some current dietary components in chronic kidney disease were studied.","PeriodicalId":42328,"journal":{"name":"Turkish Nephrology Dialysis and Transplantation Journal","volume":"27 1","pages":"14-25"},"PeriodicalIF":0.0,"publicationDate":"2018-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44160942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-19DOI: 10.5262/TNDT.2018.1001.10
Didar Şenocak, A. B. Genc, Mehmet Yildirim, Hamad Dheir, Mustafa Kösem, Savas Sipahi
{"title":"Akut Fosfat Nefropatisi","authors":"Didar Şenocak, A. B. Genc, Mehmet Yildirim, Hamad Dheir, Mustafa Kösem, Savas Sipahi","doi":"10.5262/TNDT.2018.1001.10","DOIUrl":"https://doi.org/10.5262/TNDT.2018.1001.10","url":null,"abstract":"","PeriodicalId":42328,"journal":{"name":"Turkish Nephrology Dialysis and Transplantation Journal","volume":"27 1","pages":"100-103"},"PeriodicalIF":0.0,"publicationDate":"2018-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45281408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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