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Persistent guidewire-induced arrhythmias following central venous catheterization in traumatic brain injury 外伤性脑损伤中心静脉置管后持续性导丝诱发的心律失常
IF 0.3 Q4 ANESTHESIOLOGY Pub Date : 2021-07-01 DOI: 10.4103/TheIAForum.TheIAForum_46_21
Haneesh Thakur, Nidhi Singh, J. Makkar, K. Jain
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引用次数: 0
Analgesic efficacy of ultrasound-guided erector spinae block and pectoral nerve block in patients undergoing modified radical mastectomy: A randomized control trial 超声引导下竖脊肌阻滞和胸神经阻滞对改良乳房切除术患者的镇痛效果:一项随机对照试验
IF 0.3 Q4 ANESTHESIOLOGY Pub Date : 2021-07-01 DOI: 10.4103/TheIAForum.TheIAForum_74_21
Geeta Singariya, Himani Pahuja, M. Kamal, Kusum Choudhary, S. Meena, P. Saini
Background and Aims: Modified radical mastectomy (MRM) is the commonest surgical procedure performed for carcinoma breasts. MRM is associated with considerable postoperative pain. This study was aimed to compare the analgesic efficacy of erector spinae plane (ESP) block and pectoral nerve (PECS) block. Materials and Methods: A total 70 female patients, American Society of Anesthesiologist Physical Status I-II, aged between 18 and 65 years, undergoing MRM surgery. Patients were randomly divided into two equal groups of 35 each, by computer-generated random number table. Group E patients, received ESP block with 20 mL of 0.25% levobupivacaine, and Group P patients, received PECS block with 30 mL of 0.25% of levobupivacaine. The surgical procedure was conducted under general anesthesia in both groups. The primary objective was total morphine consumption in the first 24 h and secondary objectives were intraoperative fentanyl needed, duration of analgesia, numeric rating scale (NRS) score, postoperative complications, and patient's satisfaction. The Statistical Package for the Social Science (SPSS) software version 22.0 used for statistical analysis. Results: Demographic data, hemodynamic parameters, and intraoperative fentanyl consumption were comparable between the two groups (P > 0.05). Postoperative morphine consumed in the first 24 h was less in the Group P compared to Group E (P = 0.018). The duration of analgesia was significantly prolonged in the Group P than Group E (P < 0.0001). The NRS score, postoperative complications, and patient's satisfaction were comparable. Conclusion: The PECS block is more effective analgesic modality compared to ESP blocks in patients undergoing MRM surgeries.
背景和目的:改良根治性乳房切除术(MRM)是治疗乳腺癌最常见的手术方法。MRM与相当大的术后疼痛有关。本研究旨在比较竖脊肌平面(ESP)阻滞和胸神经(PECS)阻滞的镇痛效果。材料和方法:共有70名女性患者,美国麻醉师协会,身体状况I-II,年龄在18至65岁之间,正在接受MRM手术。通过计算机生成的随机数表,将患者随机分为两组,每组35人。E组患者接受20 mL 0.25%左旋布比卡因的ESP阻滞,P组患者接受30 mL 0.25%左旋布比卡因的PECS阻滞。两组均在全身麻醉下进行手术。主要目标是前24小时的吗啡总消耗量,次要目标是术中所需芬太尼、镇痛持续时间、数字评分量表(NRS)评分、术后并发症和患者满意度。用于统计分析的社会科学统计软件包(SPSS)软件版本22.0。结果:两组患者的人口学数据、血液动力学参数和术中芬太尼消耗量具有可比性(P>0.05)。P组术后前24小时的吗啡消耗量低于E组(P=0.018),患者满意度相当。结论:在接受MRM手术的患者中,PECS阻滞比ESP阻滞更有效。
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引用次数: 0
A randomized, double-blinded comparative study of phenylephrine infusion and norepinephrine infusion for the prevention and treatment of spinal anesthesia-induced hypotension in elective and emergency cesarean deliveries 苯肾上腺素和去甲肾上腺素输注预防和治疗选择性和紧急剖宫产脊麻低血压的随机双盲对照研究
IF 0.3 Q4 ANESTHESIOLOGY Pub Date : 2021-07-01 DOI: 10.4103/TheIAForum.TheIAForum_9_21
Payal Berawala, S. Mehta, M. Chaudhari, Mayura U. Shinde
Context and Aims: Among vasopressors used to treat postspinal hypotension (PSH) in cesarean sections (CS), phenylephrine (PE) is the preferred drug at present but reflex bradycardia and thus reduction in cardiac output still pose a concern. Norepinephrine (NE), with its better pharmacological properties, may be a better alternative to overcome this risk. Hence, we did this study intending to compare both the drugs. Materials and Methods: A double-blinded, randomized, controlled trial (RCT) was carried out on 70 patients, 35 in each group-group P (PE) and group N (NE) undergoing CS, to compare and evaluate the efficacy of both drugs for preventing and treating PSH. Patients in Group P and Group N were given intravenous infusion of PE at the rate of 50 μg/min and NE at the rate of 2.5 μg/min, respectively, after the intrathecal injection of bupivacaine. The number of intermittent bolus doses required, heart rate, and mean arterial pressure (MAP) at predefined intervals were noted. Results: The incidence of hypotension calculated from the number of bolus doses required was lower in Group N than in Group P for the initial 15 min (P < 0.05). The incidence of bradycardia and vomiting was higher in Group P but were not statistically significant, while the incidences of nausea (P = 0.004) and oxygen requirement (P = 0.03) were statistically significantly higher in Group P. Conclusion: This study suggests that NE infusion is superior to PE infusion when used in the potency ratio of 20:1, to prevent and treat PSH in CS, with a lesser number of side effects.
背景和目的:在用于治疗剖宫产(CS)脊柱后低血压(PSH)的血管加压药物中,苯肾上腺素(PE)是目前首选的药物,但反射性心动过缓和心输出量减少仍然是一个问题。去甲肾上腺素(NE)具有更好的药理学特性,可能是克服这种风险的更好选择。因此,我们做这项研究的目的是比较这两种药物。材料与方法:采用双盲、随机、对照试验(RCT)对70例经CS治疗的PSH患者,P组(PE)和N组(NE)各35例,比较和评价两种药物防治PSH的疗效。P组和N组患者在鞘内注射布比卡因后,分别以50 μg/min的速率静脉滴注PE和2.5 μg/min的速率静脉滴注NE。记录所需间歇给药剂量、心率和预定间隔内的平均动脉压(MAP)。结果:N组用药前15 min低血压发生率低于P组(P < 0.05)。P组心动过缓、呕吐发生率高于P组,但无统计学意义。P组恶心发生率(P = 0.004)、需氧量发生率(P = 0.03)高于P组,有统计学意义。结论:本研究提示以20:1的效价比输注NE优于输注PE,预防和治疗CS PSH,且副作用少。
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引用次数: 2
Liver fibrosis-4 score predicts mortality in critically ill patients with coronavirus disease 2019 肝纤维化-4评分预测2019冠状病毒病危重患者的死亡率
IF 0.3 Q4 ANESTHESIOLOGY Pub Date : 2021-07-01 DOI: 10.4103/TheIAForum.TheIAForum_49_21
M. Abosamak, Ivan Szergyuk, Maria Helena Santos de Oliveira, G. Lippi, Ahmed Al-Jabbary, A. Al-Najjar, M. Albadi, B. Henry
Background: Emerging evidence suggests that liver dysfunction in the course of coronavirus disease 2019 (COVID-19) illness is a critical prognostic factor for mortality in COVID-19 patients, and the Fibrosis-4 (FIB-4) score, developed to reflect level of hepatic fibrosis, has been associated with adverse outcomes in hospitalized COVID-19 patients. This study aimed to investigate intensive care unit (ICU) admitted patients, a high-risk subpopulation, research on which is lacking. Materials and Methods: This retrospective cohort study examined FIB-4 scores and clinical endpoints including death, acute cardiac injury (ACI), acute kidney injury, and need for mechanical ventilation in critically ill COVID-19 patients, without prior hepatic disease, throughout ICU stay. Results: Of 60 patients enrolled, 35% had ICU admission FIB-4 >2.67. Among nonsurvivors, FIB-4 was significantly higher at admission (median 3.19 vs. 1.44; P < 0.001) and only a minority normalized <1.45 (36.0%). Each one-unit increment in admission FIB-4 was associated with 67.4% increased odds of death (95% confidence interval [CI], 9.8%–162.6%; P = 0.017). FIB-4 >2.67 was associated with a median survival time of 18 days from ICU admission versus 40 days with FIB-4 <2.67 (P = 0.016). Admission FIB-4 was also higher in patients developing ACI (median 4.99 vs. 1.76; P < 0.001). FIB-4 correlated with age (r = 0.449; P < 0.001), and aspartate transaminase with alanine transaminase (r = 0.674; P < 0.001) and lactate dehydrogenase (r = 0.618; P < 0.001). Conclusion: High ICU admission FIB-4 is associated with mortality in critically ill COVID-19 patients, with failure to normalize at time of death, however, the high score is likely a result of generalized cytotoxicity rather than advanced hepatic fibrosis.
背景:新出现的证据表明,2019冠状病毒病(COVID-19)病程中的肝功能障碍是COVID-19患者死亡的关键预后因素,用于反映肝纤维化水平的纤维化-4 (FIB-4)评分与住院COVID-19患者的不良结局相关。本研究旨在调查重症监护病房(ICU)住院患者,这是一个缺乏研究的高危亚人群。材料和方法:本回顾性队列研究检查了无肝脏疾病的COVID-19危重患者在ICU住院期间的FIB-4评分和临床终点,包括死亡、急性心脏损伤(ACI)、急性肾损伤和机械通气需求。结果:60例入组患者中,35%的患者入住ICU时FIB-4 bb0.2.67。在非幸存者中,入院时FIB-4明显更高(中位数3.19 vs. 1.44;P < 0.001),只有少数归一化2.67与ICU入院后18天的中位生存时间相关,而FIB-4 <2.67的中位生存时间为40天(P = 0.016)。ACI患者的入院FIB-4也更高(中位数4.99 vs 1.76;P < 0.001)。FIB-4与年龄相关(r = 0.449;P < 0.001),谷草转氨酶与丙氨酸转氨酶(r = 0.674;P < 0.001)和乳酸脱氢酶(r = 0.618;P < 0.001)。结论:ICU入院FIB-4评分高与COVID-19危重患者死亡率相关,死亡时FIB-4评分未能恢复正常,但较高评分可能是全身性细胞毒性所致,而非晚期肝纤维化所致。
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引用次数: 0
The dilemma of extubation of a patient with congenital cyanotic heart disease 先天性紫绀型心脏病患者拔管的困境
IF 0.3 Q4 ANESTHESIOLOGY Pub Date : 2021-07-01 DOI: 10.4103/TheIAForum.TheIAForum_25_21
Hariprasad Ramalingam, Ankur Sharma, Hareesh Ayyawar, P. Bhatia, Nikhil Kothari
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引用次数: 0
Indian association of paediatric anaesthesia advisory for pain management in neonates and preverbal children 印度儿科麻醉协会咨询疼痛管理的新生儿和学龄前儿童
IF 0.3 Q4 ANESTHESIOLOGY Pub Date : 2021-07-01 DOI: 10.4103/TheIAForum.TheIAForum_4_21
I. Sen, Anju Gupta, Y. Chandrika, G. Nath, E. Varghese
In the past, management of pain in neonates was regarded as unnecessary, with the belief that neonates have an immature nervous system and do not perceive pain. Later studies confirmed that neonates certainly do feel pain, though they lack the inhibitory mechanisms that modulate excruciating stimuli, unlike in older children. Repeated painful encounters experienced in the newborn period are associated with poor cognitive and motor development by 1 year of age. Pain in preverbal infants and children is also poorly recognized and often undertreated. Neonates and preverbal children cannot verbally communicate their pain and discomfort but express them through specific behavioral, physiological, and biochemical responses. Several pain measurement tools have been developed for young children as surrogate measures of pain. To achieve optimum postoperative or procedural pain relief, easily understandable tools and a multimodal treatment module should be tailor-made for each health-care facility that cares for neonates and young infants. The aim of this advisory is to outline key concepts of pain assessment in neonates and preverbal children and suggest a rational approach to its management by all anesthesiologists, pediatricians, nursing staff, and other medical personnel caring for these children. The Indian Association of Paediatric Anaesthesia (IAPA) convened an online meeting in April 2020 to formulate the advisory on pain management in neonates and preverbal children under the chairmanship of Dr. Elsa Varghese, President IAPA, and members of the guideline committee. After several such meetings and revisions using feedback from IAPA members, the final guidelines were released in October 2020 on the IAPA website. Recommendations: Pain relief should generally be accomplished with a combination of nonpharmacologic approaches and pharmacologic techniques in a stepwise tiered manner by escalating type and dose of analgesia with anticipated increases in procedural pain. Nonpharmacological distraction measures may be sufficient for minor needle procedures like vaccination and venipuncture and may be offered as a first step and to complement other pain management remedies. An interdisciplinary approach involving pharmacologic, cognitive-behavioral, psychologic, and physical treatments should be employed whenever feasible.
过去,对新生儿疼痛的治疗被认为是不必要的,因为人们认为新生儿的神经系统不成熟,不会感知疼痛。后来的研究证实,新生儿确实会感到疼痛,尽管与年龄较大的儿童不同,他们缺乏调节剧烈刺激的抑制机制。新生儿时期反复经历的疼痛与1岁时认知和运动发育不良有关。早产儿和儿童的疼痛也很少被认识到,而且往往治疗不足。新生儿和言语前儿童不能用言语表达他们的疼痛和不适,而是通过特定的行为、生理和生化反应来表达。已经为幼儿开发了几种疼痛测量工具,作为疼痛的替代测量方法。为了实现最佳的术后或程序性疼痛缓解,应为每个照顾新生儿和幼儿的医疗机构量身定制易于理解的工具和多模式治疗模块。本咨询的目的是概述新生儿和言语前儿童疼痛评估的关键概念,并建议所有麻醉师、儿科医生、护理人员和其他照顾这些儿童的医务人员合理管理疼痛评估。印度儿科麻醉协会(IAPA)于2020年4月召开了一次在线会议,在IAPA主席Elsa Varghese博士和指导委员会成员的主持下,制定新生儿和语言前儿童疼痛管理咨询意见。在几次此类会议和利用IAPA成员的反馈进行修订后,最终指南于2020年10月在IAPA网站上发布。建议:疼痛缓解通常应通过非药物方法和药理学技术的结合,逐步分级,通过增加镇痛类型和剂量来达到预期的手术疼痛增加。非药物分散注意力的措施可能足以用于疫苗接种和静脉穿刺等小针头手术,并可作为第一步提供,以补充其他疼痛管理补救措施。只要可行,应采用包括药理学、认知行为学、心理学和物理治疗在内的跨学科方法。
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引用次数: 0
A migrated guidewire of a hemodialysis catheter in a COVID-19 patient COVID-19患者血液透析导管导丝移位
IF 0.3 Q4 ANESTHESIOLOGY Pub Date : 2021-07-01 DOI: 10.4103/TheIAForum.TheIAForum_44_21
Sarfaraz Ahmad, S. Naaz, Neeraj Kumar, Amarjeet Kumar
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引用次数: 0
Perfusion index as a monitor to determine the success of a peripheral nerve block: Is the truth subjective or objective? 灌注指数作为确定周围神经阻滞成功与否的监视器:真相是主观的还是客观的?
IF 0.3 Q4 ANESTHESIOLOGY Pub Date : 2021-07-01 DOI: 10.4103/TheIAForum.TheIAForum_103_21
S. Sanghavi, G. Biyani
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引用次数: 0
Ultrasound-guided dilation of central venous catheter track to prevent dilator-related injury 超声引导下中心静脉导管径迹扩张预防扩张器相关损伤
IF 0.3 Q4 ANESTHESIOLOGY Pub Date : 2021-07-01 DOI: 10.4103/TheIAForum.TheIAForum_39_21
Hariprasad Ramalingam, Shipra Roy, Ankur Sharma, Nikhil Kothari, S. Goyal
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引用次数: 0
Stellate ganglion block and neurolysis for refractory ventricular arrhythmia 难治性室性心律失常的星状神经节阻滞和神经松解
IF 0.3 Q4 ANESTHESIOLOGY Pub Date : 2021-07-01 DOI: 10.4103/TheIAForum.TheIAForum_13_21
A. Aggarwal, Rohit Balyan, Varun Suresh, B. Gupta
Enhanced electrical activity, ventricular arrhythmia (VA), and cardiac instability due to increased sympathetic tone may be refractory to standard medical treatment and ablation procedures. Stellate ganglion block (SGB) has been used to treat refractory VA; however, there is insufficient information in the literature on its long-term outcome. Herein, we described three patients that were successfully treated with ultrasound-guided left SGB (LSGB) and chemical neurolysis. Ultrasound-guided LSGB may be considered as rescue or bridge therapy for stabilizing ventricular rhythm before a definitive procedure is planned.
交感神经张力增高引起的电活动增强、室性心律失常(VA)和心脏不稳定,可能对标准的医学治疗和消融手术难以治愈。星状神经节阻滞(SGB)已被用于治疗难治性VA;然而,文献中关于其长期结果的信息不足。本文中,我们描述了3例超声引导下左侧SGB (LSGB)和化学神经松解术成功治疗的患者。超声引导下的LSGB可能被认为是在确定手术计划之前稳定心室节律的抢救或桥梁治疗。
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引用次数: 0
期刊
Indian Anaesthetists Forum
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