Pub Date : 2020-12-22DOI: 10.5606/DSUFNJT.2020.017
A. Ekmekçi
e-mail: aslimelike01@gmail.com ABSTRACT Autism spectrum disorder (ASD) is a social behavior disorder and awareness on ASD has been increasing nowadays. Social deficiencies and repetitive movements constitute the symptoms of ASD occurring in childhood. As there is no biological marker in autism, parental and clinician approaches are based on diagnosis. Genetic and environmental factors play a role in autism, and its prevalence has been increasing in recent years. The process and amount of exposure to environmental factors create differences in the cause of autism. Although it is unclear yet whether autism is a cause or result, impaired intestinal flora is among the symptoms of autism. Factors such as nutrition approaches and perinatal factors have been thought to play a role in intestinal flora dysbiosis. Metabolites that cross the blood-brain barrier in the intestinal flora dysbiosis can cause morphological changes in the hippocampus in the brain. Various dietary approaches and fecal microbiota transplantation have become candidates for autism treatment methods to improve the deteriorated flora. In this review, we discuss the effects of therapeutic nutritional approaches and fecal transplantation by examining the relationship between ASD and
{"title":"The role of intestinal flora in autism and nutritional approaches","authors":"A. Ekmekçi","doi":"10.5606/DSUFNJT.2020.017","DOIUrl":"https://doi.org/10.5606/DSUFNJT.2020.017","url":null,"abstract":"e-mail: aslimelike01@gmail.com ABSTRACT Autism spectrum disorder (ASD) is a social behavior disorder and awareness on ASD has been increasing nowadays. Social deficiencies and repetitive movements constitute the symptoms of ASD occurring in childhood. As there is no biological marker in autism, parental and clinician approaches are based on diagnosis. Genetic and environmental factors play a role in autism, and its prevalence has been increasing in recent years. The process and amount of exposure to environmental factors create differences in the cause of autism. Although it is unclear yet whether autism is a cause or result, impaired intestinal flora is among the symptoms of autism. Factors such as nutrition approaches and perinatal factors have been thought to play a role in intestinal flora dysbiosis. Metabolites that cross the blood-brain barrier in the intestinal flora dysbiosis can cause morphological changes in the hippocampus in the brain. Various dietary approaches and fecal microbiota transplantation have become candidates for autism treatment methods to improve the deteriorated flora. In this review, we discuss the effects of therapeutic nutritional approaches and fecal transplantation by examining the relationship between ASD and","PeriodicalId":423654,"journal":{"name":"Demiroglu Science University Florence Nightingale Transplantation Journal","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127187466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-22DOI: 10.5606/DSUFNJT.2020.016
Ensar Demir
e-mail: demiir.ensar@gmail.com ABSTRACT Transcranial magnetic stimulation (TMS), which is a non-invasive procedure, has become more and more prominent with promising studies in the last two decades. With a very low rate of side effects, TMS has the potential to be effective in many diseases, particularly in psychiatric disorders such as depression, obsessive-compulsive disorder, and epilepsy. In this review, we analyze and compile studies on the development and current status of TMS and the areas where it is used or can be used. The data were obtained based on the review of about 200 studies in the literature search between January 1995 and September 2020 by scanning two online database publishing in English and one online database publishing in Turkish and English. Tens of studies examined have yielded very successful results for TMS. In the following years, it seems to enter our lives among the combined treatment methods even at worst. Undoubtedly, this cannot be ignored, but it has not been standardized yet, including two or three United States Food and Drug Administration-approved applications. Still different methodologies and protocols are available. Above all, the fact that there are unsuccessful studies or a large number of studies showing that the effect of TMS decreases significantly in the long-term indicates that it should be approached with caution.
摘要经颅磁刺激(Transcranial magnetic stimulation, TMS)作为一种非侵入性的治疗手段，在近二十年的研究中越来越受到重视。由于副作用率极低，经颅磁刺激有可能对许多疾病有效，特别是对抑郁症、强迫症和癫痫等精神疾病。本文对经颅磁刺激的发展、现状、应用领域和应用前景等方面的研究进行了分析和综述。数据是基于1995年1月至2020年9月期间文献检索中约200项研究的综述，通过扫描两个英文在线数据库和一个土耳其语和英语在线数据库。数十项经颅磁刺激试验取得了非常成功的结果。在接下来的几年里，它似乎在最坏的情况下也进入了我们的生活。毫无疑问，这是不容忽视的，但它还没有被规范，包括两三个美国食品和药物管理局批准的申请。仍然有不同的方法和协议可用。最重要的是，有不成功的研究或大量的研究表明经颅磁刺激的效果在长期内显著下降，这表明应该谨慎对待。
{"title":"Transcranial magnetic stimulation application fields","authors":"Ensar Demir","doi":"10.5606/DSUFNJT.2020.016","DOIUrl":"https://doi.org/10.5606/DSUFNJT.2020.016","url":null,"abstract":"e-mail: demiir.ensar@gmail.com ABSTRACT Transcranial magnetic stimulation (TMS), which is a non-invasive procedure, has become more and more prominent with promising studies in the last two decades. With a very low rate of side effects, TMS has the potential to be effective in many diseases, particularly in psychiatric disorders such as depression, obsessive-compulsive disorder, and epilepsy. In this review, we analyze and compile studies on the development and current status of TMS and the areas where it is used or can be used. The data were obtained based on the review of about 200 studies in the literature search between January 1995 and September 2020 by scanning two online database publishing in English and one online database publishing in Turkish and English. Tens of studies examined have yielded very successful results for TMS. In the following years, it seems to enter our lives among the combined treatment methods even at worst. Undoubtedly, this cannot be ignored, but it has not been standardized yet, including two or three United States Food and Drug Administration-approved applications. Still different methodologies and protocols are available. Above all, the fact that there are unsuccessful studies or a large number of studies showing that the effect of TMS decreases significantly in the long-term indicates that it should be approached with caution.","PeriodicalId":423654,"journal":{"name":"Demiroglu Science University Florence Nightingale Transplantation Journal","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126973811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-22DOI: 10.5606/DSUFNJT.2020.015
Alper Kurt
e-mail: alper.kurt@ozu.edu.tr ABSTRACT Many of the drugs used in the treatment of diseases, such as cancer, spread throughout the body, causing tissue and healthy cell loss. Patients taking these medications may experience serious side effects. To overcome these problems, scientists have developed many types of microrobots and operating principles which can release drugs manageably and locally and can be remotely controlled with external sources. In this review, four different movement types that we selected from the movement mechanisms of microrobots are examined in detail. These motion types are magnetic motion, acoustic motion, microorganism-based motion, and chemical reaction-based motion, respectively. In this review, we discuss how each movement mechanism works and what kind of experimental studies it has today. In addition, the shortcomings of these movement mechanisms and the aspects that need to be improved are mentioned. In general, this review sheds light into how microrobots facilitate human health with targeted drug delivery technology and forthcoming
{"title":"Locomotion methods of microrobots and targeted drug delivery","authors":"Alper Kurt","doi":"10.5606/DSUFNJT.2020.015","DOIUrl":"https://doi.org/10.5606/DSUFNJT.2020.015","url":null,"abstract":"e-mail: alper.kurt@ozu.edu.tr ABSTRACT Many of the drugs used in the treatment of diseases, such as cancer, spread throughout the body, causing tissue and healthy cell loss. Patients taking these medications may experience serious side effects. To overcome these problems, scientists have developed many types of microrobots and operating principles which can release drugs manageably and locally and can be remotely controlled with external sources. In this review, four different movement types that we selected from the movement mechanisms of microrobots are examined in detail. These motion types are magnetic motion, acoustic motion, microorganism-based motion, and chemical reaction-based motion, respectively. In this review, we discuss how each movement mechanism works and what kind of experimental studies it has today. In addition, the shortcomings of these movement mechanisms and the aspects that need to be improved are mentioned. In general, this review sheds light into how microrobots facilitate human health with targeted drug delivery technology and forthcoming","PeriodicalId":423654,"journal":{"name":"Demiroglu Science University Florence Nightingale Transplantation Journal","volume":"86 16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126284831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-22DOI: 10.5606/DSUFNJT.2020.014
Mihriban Akkoz
{"title":"The relationship between social media use and narcissism","authors":"Mihriban Akkoz","doi":"10.5606/DSUFNJT.2020.014","DOIUrl":"https://doi.org/10.5606/DSUFNJT.2020.014","url":null,"abstract":"","PeriodicalId":423654,"journal":{"name":"Demiroglu Science University Florence Nightingale Transplantation Journal","volume":"99 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131464920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-22DOI: 10.5606/DSUFNJT.2020.018
Mine Ün
Türkiye. e-posta: unmine13@gmail.com ABSTRACT Echinococcosis also known as hydatid cyst disease (HD) is caused by the transmission of Echinococcus granulosus (E. granulosus) from animals to humans. Transmission is by fecal-oral contact, usually from infected domestic dogs or their stools containing eggs. E. granulosus forms unilocular cysts, particularly in liver and lungs in humans following infection. Although the most common location is the liver, hydatid cyst formation can be seen almost everywhere in the body. In patients with liver cysts, abdominal pain and anorexia are the most common manifestations. It can compress the bile ducts, leading to jaundice. Cysts in the lungs present with symptoms as chronic cough, dyspnea, pleuritic chest, pain and hemoptysis. Ultrasound is a rapid and accurate method to detect liver lesions with a precision up to 90 to 95%. Hydatid cyst usually has the appearance of a simple fluid-filled cyst on ultrasound; however, the appearance and characteristics may change depending on the development stage of the disease. Computed tomography (CT) scan and magnetic resonance imaging (MRI) are more sensitive and specific in the detection and characterization of HD. Surgical treatment has long been accepted as the definitive treatment method for hydatid cyst. It can be performed in about 90% of patients, if the disease has not progressed excessively. In addition, the puncture, aspiration, injection, and re-aspiration (PAIR) technique, which is a less invasive approach, is an alternative treatment performed by aspirating the cystic fluid with ultrasound or CT. In addition, two medications as mebendazole and albendazole, are used for the treatment of hydatid cyst in patients, if necessary. The management and treatment approach of hydatid cyst depends on the affected organ, the number of cysts, the presence of cystic-biliary communication, secondary bacterial infection, and hemorrhage. Therefore, it is of utmost importance to evaluate each case thoroughly and carefully to achieve the
{"title":"Hydatid cyst and treatment","authors":"Mine Ün","doi":"10.5606/DSUFNJT.2020.018","DOIUrl":"https://doi.org/10.5606/DSUFNJT.2020.018","url":null,"abstract":"Türkiye. e-posta: unmine13@gmail.com ABSTRACT Echinococcosis also known as hydatid cyst disease (HD) is caused by the transmission of Echinococcus granulosus (E. granulosus) from animals to humans. Transmission is by fecal-oral contact, usually from infected domestic dogs or their stools containing eggs. E. granulosus forms unilocular cysts, particularly in liver and lungs in humans following infection. Although the most common location is the liver, hydatid cyst formation can be seen almost everywhere in the body. In patients with liver cysts, abdominal pain and anorexia are the most common manifestations. It can compress the bile ducts, leading to jaundice. Cysts in the lungs present with symptoms as chronic cough, dyspnea, pleuritic chest, pain and hemoptysis. Ultrasound is a rapid and accurate method to detect liver lesions with a precision up to 90 to 95%. Hydatid cyst usually has the appearance of a simple fluid-filled cyst on ultrasound; however, the appearance and characteristics may change depending on the development stage of the disease. Computed tomography (CT) scan and magnetic resonance imaging (MRI) are more sensitive and specific in the detection and characterization of HD. Surgical treatment has long been accepted as the definitive treatment method for hydatid cyst. It can be performed in about 90% of patients, if the disease has not progressed excessively. In addition, the puncture, aspiration, injection, and re-aspiration (PAIR) technique, which is a less invasive approach, is an alternative treatment performed by aspirating the cystic fluid with ultrasound or CT. In addition, two medications as mebendazole and albendazole, are used for the treatment of hydatid cyst in patients, if necessary. The management and treatment approach of hydatid cyst depends on the affected organ, the number of cysts, the presence of cystic-biliary communication, secondary bacterial infection, and hemorrhage. Therefore, it is of utmost importance to evaluate each case thoroughly and carefully to achieve the","PeriodicalId":423654,"journal":{"name":"Demiroglu Science University Florence Nightingale Transplantation Journal","volume":"04 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129590912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-22DOI: 10.5606/DSUFNJT.2020.013
Sura Sanem Köse
e-mail: sura_sanem98@hotmail.com ABSTRACT Symptoms such as personality disorder, adaptation to the environment, functionality problems, and tension-anxiety can be observed. It is a set of physical, intellectual, and mental characteristics defined as thinking, functioning, and behavioral disorders. It is also defined as a mental problem based on the observation of long-term adaptation problems and strict tendencies. A wide range of factors from genetics to environment plays a role in the development of personality disorders. Although personality disorders have been studied extensively in recent years, the main causes and treatments have not been clearly understood, yet. In this review, we discuss symptoms of personality disorders together with biological- environmental causes
{"title":"Personality disorders diagnosis, causes, and treatments","authors":"Sura Sanem Köse","doi":"10.5606/DSUFNJT.2020.013","DOIUrl":"https://doi.org/10.5606/DSUFNJT.2020.013","url":null,"abstract":"e-mail: sura_sanem98@hotmail.com ABSTRACT Symptoms such as personality disorder, adaptation to the environment, functionality problems, and tension-anxiety can be observed. It is a set of physical, intellectual, and mental characteristics defined as thinking, functioning, and behavioral disorders. It is also defined as a mental problem based on the observation of long-term adaptation problems and strict tendencies. A wide range of factors from genetics to environment plays a role in the development of personality disorders. Although personality disorders have been studied extensively in recent years, the main causes and treatments have not been clearly understood, yet. In this review, we discuss symptoms of personality disorders together with biological- environmental causes","PeriodicalId":423654,"journal":{"name":"Demiroglu Science University Florence Nightingale Transplantation Journal","volume":"147 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127432281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-22DOI: 10.5606/DSUFNJT.2020.012
Alper Tanrikulu, O. Erbaş
Correspondence: Alper Tanrıkulu. Deneysel Tıp Enstitüsü, 41470 Gebze-Kocaeli, Türkiye. e-mail: tanriklualper@gmail.com ABSTRACT Schizophrenia is a neurodegenerative disease in which cognitive and behavioral disorders coexist. Based on magnetic resonance imaging (MRI) studies, there are problems in neuron connections and the prefrontal lobe is almost completely disrupted. It is highly inherited. Genome scans have shown that variations in the major histocompatibility complex (MHC) genes may be a risk factor for schizophrenia. Detection of the differences in allele frequency is also important in the etiology studies of the disease. Schizophrenia is a very complex disease due to dysfunction of almost entire neurocognitive related systems. With the discovery of antipsychotic drugs, many hypotheses have been put forward on the etiology of the disease. One of them is dopamine hypothesis of schizophrenia and the other is glutamate hypothesis of schizophrenia. Antipsychotic drugs alleviate psychosis symptoms by interacting with protein receptors or ion channels involved in dopamine glutamate and gamma aminobutyric acid (GABA) pathways. In this review, we discuss dopamine and glutamate hypotheses based on the etiology of schizophrenia and the genes that have the most evidence for their relationship with the disease.
通信:Alper Tanrıkulu。Deneysel Tıp Enstitüsü， 41470 Gebze-Kocaeli, t。精神分裂症是一种认知和行为障碍并存的神经退行性疾病。根据磁共振成像(MRI)研究，神经元连接出现问题，前额叶几乎完全中断。这是高度遗传的。基因组扫描显示，主要组织相容性复合体(MHC)基因的变异可能是精神分裂症的一个危险因素。检测等位基因频率的差异在该病的病因学研究中也很重要。精神分裂症是一种非常复杂的疾病，几乎整个神经认知相关系统都出现了功能障碍。随着抗精神病药物的发现，人们对该病的病因提出了许多假设。一种是多巴胺假说另一种是谷氨酸假说。抗精神病药物通过与多巴胺谷氨酸和γ氨基丁酸(GABA)通路中的蛋白受体或离子通道相互作用来减轻精神病症状。在这篇综述中，我们讨论了基于精神分裂症病因的多巴胺和谷氨酸假说，以及最有证据表明它们与疾病的关系的基因。
{"title":"Genetic basis of schizophrenia: Basic hypothesis pathways and gene functions","authors":"Alper Tanrikulu, O. Erbaş","doi":"10.5606/DSUFNJT.2020.012","DOIUrl":"https://doi.org/10.5606/DSUFNJT.2020.012","url":null,"abstract":"Correspondence: Alper Tanrıkulu. Deneysel Tıp Enstitüsü, 41470 Gebze-Kocaeli, Türkiye. e-mail: tanriklualper@gmail.com ABSTRACT Schizophrenia is a neurodegenerative disease in which cognitive and behavioral disorders coexist. Based on magnetic resonance imaging (MRI) studies, there are problems in neuron connections and the prefrontal lobe is almost completely disrupted. It is highly inherited. Genome scans have shown that variations in the major histocompatibility complex (MHC) genes may be a risk factor for schizophrenia. Detection of the differences in allele frequency is also important in the etiology studies of the disease. Schizophrenia is a very complex disease due to dysfunction of almost entire neurocognitive related systems. With the discovery of antipsychotic drugs, many hypotheses have been put forward on the etiology of the disease. One of them is dopamine hypothesis of schizophrenia and the other is glutamate hypothesis of schizophrenia. Antipsychotic drugs alleviate psychosis symptoms by interacting with protein receptors or ion channels involved in dopamine glutamate and gamma aminobutyric acid (GABA) pathways. In this review, we discuss dopamine and glutamate hypotheses based on the etiology of schizophrenia and the genes that have the most evidence for their relationship with the disease.","PeriodicalId":423654,"journal":{"name":"Demiroglu Science University Florence Nightingale Transplantation Journal","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133315841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-31DOI: 10.5606/DSUFNJT.2019.003
Mine Ün, O. Erbaş
İletişim adresi: Mine Ün. İstanbul Aydın Üniversitesi Tıp Fakültesi, 34295 Sefaköy, Küçükçekmece, İstanbul, Türkiye. e-posta: unmine13@gmail.com ABSTRACT Type 1 Diabetes mellitus is an autoimmune disease characterized by the destruction of insulin-producing beta cells in the pancreas. These patients become dependent on external insulin because they cannot produce insulin. However, in the long-term, exogenous insulin treatment does not prevent diabetic complications. In order to find an alternative diabetic treatment, clinical studies have demonstrated that pancreas transplantation or purified pancreatic islet transplantation could maintain control over blood sugar levels in Type 1 diabetes patients and were more effective treatment methods for these patients. Pancreatic islet transplantation is carried out with a smaller transplantation mass compared to complete pancreas transplantation. This also allows a more minor operation and transplantation of less immunologic tissue. Therefore, new methods aim to improve pancreatic islet transplantation.
İletişim地址:我的Ün。İstanbul Aydın Üniversitesi Tıp fak ltesi, 34295 Sefaköy, k ekmece， İstanbul, t rkiye。摘要1型糖尿病是一种自身免疫性疾病，其特征是胰腺中产生胰岛素的β细胞被破坏。这些患者依赖于外部胰岛素，因为他们不能产生胰岛素。然而，从长期来看，外源性胰岛素治疗并不能预防糖尿病并发症。为了寻找一种替代的糖尿病治疗方法，临床研究表明，胰腺移植或纯化胰岛移植可以维持1型糖尿病患者血糖水平的控制，是更有效的治疗方法。胰岛移植与完全胰腺移植相比，移植质量更小。这也允许更小的手术和较少免疫组织的移植。因此，新的方法旨在改善胰岛移植。
{"title":"Pancreatic islet cell transplantation","authors":"Mine Ün, O. Erbaş","doi":"10.5606/DSUFNJT.2019.003","DOIUrl":"https://doi.org/10.5606/DSUFNJT.2019.003","url":null,"abstract":"İletişim adresi: Mine Ün. İstanbul Aydın Üniversitesi Tıp Fakültesi, 34295 Sefaköy, Küçükçekmece, İstanbul, Türkiye. e-posta: unmine13@gmail.com ABSTRACT Type 1 Diabetes mellitus is an autoimmune disease characterized by the destruction of insulin-producing beta cells in the pancreas. These patients become dependent on external insulin because they cannot produce insulin. However, in the long-term, exogenous insulin treatment does not prevent diabetic complications. In order to find an alternative diabetic treatment, clinical studies have demonstrated that pancreas transplantation or purified pancreatic islet transplantation could maintain control over blood sugar levels in Type 1 diabetes patients and were more effective treatment methods for these patients. Pancreatic islet transplantation is carried out with a smaller transplantation mass compared to complete pancreas transplantation. This also allows a more minor operation and transplantation of less immunologic tissue. Therefore, new methods aim to improve pancreatic islet transplantation.","PeriodicalId":423654,"journal":{"name":"Demiroglu Science University Florence Nightingale Transplantation Journal","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116961870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-31DOI: 10.5606/dsufnjt.2019.007
Mine Ün
e-posta: unmine13@gmail.com ABSTRACT Although intestinal transplantation has become a standard in treating intestinal failure today, it has faced significant challenges up to this point. Intestinal transplantation, which is relatively more complicated and has higher likelihood of rejection compared to other solid organ transplantations such as the liver, kidneys, and heart, has gone a long way since the 1900s and has achieved successful results.
{"title":"Intestinal transplantation","authors":"Mine Ün","doi":"10.5606/dsufnjt.2019.007","DOIUrl":"https://doi.org/10.5606/dsufnjt.2019.007","url":null,"abstract":"e-posta: unmine13@gmail.com ABSTRACT Although intestinal transplantation has become a standard in treating intestinal failure today, it has faced significant challenges up to this point. Intestinal transplantation, which is relatively more complicated and has higher likelihood of rejection compared to other solid organ transplantations such as the liver, kidneys, and heart, has gone a long way since the 1900s and has achieved successful results.","PeriodicalId":423654,"journal":{"name":"Demiroglu Science University Florence Nightingale Transplantation Journal","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123663280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：