Cuadernos de Bioetica最新文献

The main aim of this paper is to define an answer, in a key time before COVID19, if it is indeed possible to do so, as to the difference between pain and suffering. In order to do so, we will refer to, although not exclusively, the reflexions of the German philosopher Robert Spaemann. To finish, the question of death will briefly be analysed.

Transgenesis is a parcel of biotechnology that allows the introduction of genetic information not proper to the genome of living beings, apart from the mechanisms of natural genetic exchange. This made possible to address important applications in bacteria, animals and plants with significant benefits in health, food and environmental aspects. Since its origin, the production of genetically modified organisms (GMOs) caused some controversy due to the possible negative influence of these organisms or their derived products on health and the environment. Over time, genetic modification techniques have renewed, giving way to others of greater precision, simplicity and safety. Currently the CRISPR-Cas9 technique is widely used, which allows to edit, modify or eliminate specific DNA sequences, with multiple applications in the same fields of transgenesis, but adding greater simplicity, security and lower cost. This work presents the main techniques, applications and ethical implications of using these methods and their perspectives in an ever-evolving world. The bacteria for obtaining products of pharmacological interest, new varieties of cultivated plants of higher production, more resistance to growth limiting agents and better nutritional quality and domestic animals modified genetically, offer a set of advantages needed to address the global challenges that affect the lives of many people around the world.

To show hospital health professionals' knowledge on ABC. Observational, descriptive, transversal and analytical research using questionnaires designed ad hoc. Comparative statistical analysis applying Ji-square by Pearson and Fisher tests. Binary logistic regression model to determine the odd ratios (O.R) having education level and sex as independent variables. A 4% accuracy was accepted, as well as a confidence Interval of 95% and a p value inferior to 0.05. The data was processed by IBM SPSS Statistics v.20 software. Required sample of 351 professionals (108 doctors and other related graduate; 144 nurses and 99 clinical assistants (TCAE)). 276 participants (78,6%; IC95%: 74,0-82,2); of which 84 doctors (77,8%; IC95%: 68,8-85,2); 120 nurses (83,3%; IC95%: 76,2-89,0) y 71 TCAE (71,7%; IC95%: 61,7-80,3), predominantly women (194, 70,3%). 228 (82,6%) were aware of the existence of ABC. Both doctors and nurses had more knowledge of ABC than clinical assistants (p 0,0001 for both), however there was not significative difference between doctors and nurses (p=0,836; OR:0,901; IC95%: 0,334-2,228). 124 (45,1%) knew the functions of ABC, with doctors displaying more knownledge than both nurses and clinical assistants (p=0,002 and p 0,0001 respectively) and nurses showing more familiarity than clinical assistants (p=0,008). 129(47,6%) communicated ethical conflicts, showing no significative difference between doctors and nurses (p=0,119). However, clinical assistants displayed different behabiour than the other two groups in this regard (p 0,0001 and p=0,001 respectively). Of all, 47 (22,4%) communicated they had ethical conflicts regarding the beginning and end of life. The knowledge on the existence of the ABC is high, however there is poor knowledge around its functions. Among health professionals, doctors and nurses know him better than TCAE. Matters related with the beginning and end of life cause most of ethical conflicts.

The authors make an interdisciplinary approach to prostitution, with emphasis on women. From the psychological point of view, they adopt a systemic approach, and validate the expression ″persons in prostitution situation″; they review the state of the art in legal matters and public policies, making a critical analysis based on the tradition of realistic thinking. They argue that one of the fundamental issues involved is the unity of the human person and the role that intimacy plays in it, polemicizing against usual objections. Finally, they state their conclusions, which implies affirming that prostitution considers human person as object, and therefore it is contrary to her or his dignity.

Epigenetics deals with the study of structural modifications in the regions of the genome, by methylation of DNA or chromosomal histones, or other mechanisms that affect the expression of genes without altering the base composition of DNA. Cell differentiation, which is established in embryonic development from blastocyst status, is the consequence of differential cell reprogramming, based on programmed epigenetic modifications, which establish differences in the epigenome of cells and tissues. Maternal and paternal genomes of the gametes have genomic imprinting differences due to DNA methylation or other epigenetic modifications established in the germinal cells during gametogenesis. Maternal and paternal parental genomes present differences of genomic imprinting, which are established by DNA methylation or other epigenetic modifications during embryonic development, in the primordial germ cells. Unscheduled epigenetic modifications may also occur under the influence of uncontrolled environmental factors, which can lead to health disturbances. However, all epigenetic modifications are erased after fertilization and those affecting the germ line of the embryo or fetus during their development are not inherited beyond the second generation, - F2 -. Epigenetics should not be considered a new type of inheritance with transgenerational consequences, but as a set of mechanisms related to genetic regulation.

Gender was an important component in the May '68 revolution. However, what was originally proposed as an effort for equality and the defense of the legitimate prerogatives of women, evolved into a movement, gender post-feminism, which it set aside their real interests and needs, pursuing other, even contradictory, goals. This article tries to justify the previous statement, starting from some of the main currents of thought what were at the base of the revolution.

Lately, number of divorces is increasing, nevertheless, a parents' divorce can become a traumatic problem for paediatric patients. Consequently, the aim of this study was to analyze the ethical conflicts that appear in the relationship between physician/parents/son/daughter, and more specifically those that a divorce generates. A descriptive study was developed through a survey composed by 39 items. Previously, an exhaustive bibliographic analysis was carried out. Our results show that only 35% of paediatricians interviewed have been educated in bioethics although this issue is important in daily practice. Other items show that 57,5% would not cancel a pharmacological treatment in order to improve quality of life. Also, they would react against a wrong parents' decision (82,5%). They give low value to the minor`s decision (6,05%), and rarely inform exclusively to adolescents (5%). In contrast, paediatricians sometimes ask to adolescents (20%) in first place and involved them to decide in 90% of cases. Besides, there are differences in the relation with fathers and mothers, 17,5% of mothers are informed exclusively, a fact that never happens with fathers. Ethics has an intrinsic value very important in daily clinical decisions in order to respect the rules and to adapt them to the situation of every paediatric patient. When an important ethical conflict become, as a divorce is, it is essential to know who must be informed and the rights everyone has to make a decision. It is complicated to the paediatricians yet to develop 41/2002 law for Patient's autonomy.

The interaction between doctors and pharmaceutical companies has been and is common, occurs in multiple ways and has proven, in many cases, to be necessary for the development of medicine. However, some of the sales techniques of the pharmaceutical industry are not ethically acceptable and can compromise the independence of physicians. An ethical dilemma arises from a real case in which the search for vulnerability in prescription based on a donation by a pharmaceutical company was not easy to identify.

The crisis of COVID-19 leaves us a teaching in the form of reminiscence. We do not learn anything new from it, but it reminds us of something we knew and forgot. It shows us in a new light our vulnerability, the impossibility of protecting ourselves perfectly through prediction and control. The sciences do not predict with certainty and the technologies do not manage to have everything under control, although the former and the latter have many other and worthwhile functions. Ideologies do not see the future, no matter how much they pretend to do so. However, we are not without reliable guidance in deciding our actions. This orientation must be sought in being, not in the future. It is fidelity to our common human nature that must advise us. It is the full realization of our personal being, of our peculiar vocation, that guides us. So, the means for self-realization consists in the development of a virtuous character. The same character that has mitigated the ravages of the pandemic, given that, to some degree, it was already present in many of our fellow citizens. The same that would have alleviated the suffering even more if it had been available in more people and to a greater degree.