Eric Puryear, Jennifer Van Puymbrouck, D. Angulo, K. Drew, Lee Ann Hollenbeck, Dominic Battré, A. Schilling, David Jabon, G. Laszewski
Research in proteomics has created two significant needs: the need for an accurate public database of empirically derived mass spectrum information and the need for managing the I/O and organization of mass spectrometry data in the form of files and structures. Lack of an empirically derived database limits the ability of proteomic researchers to identify and study proteins. Managing the I/O and organization of mass spectrometry data is often time-consuming due to the many fields that need to be set and retrieved. As a result, incompatibilities and inefficiencies are created by each programmer handling this in his or her own way. Until recently, storage space and computing power has been the limiting factor in developing tools to handle the vast amount of mass spectrometry information. Now the resources are available to store, organize, and analyze mass spectrometry information.The Illinois Bio-Grid Mass Spectrometry Database is a database of empirically derived tandem mass spectra of peptides created to provide researchers with an organized and searchable database of curated spectrum information to allow more accurate protein identification. The Mass Spectrometry I/O Project creates a framework that handles mass spectrometry data I/O and data organization, allowing researchers to concentrate on data analysis rather than I/O. In addition, the Mass Spectrometry I/O Project leverages several cross-platform and portability-enhancing technologies, allowing it to be utilized on a variety of hardware and operating systems.
{"title":"Achieving I/O improvements in a mass spectral database","authors":"Eric Puryear, Jennifer Van Puymbrouck, D. Angulo, K. Drew, Lee Ann Hollenbeck, Dominic Battré, A. Schilling, David Jabon, G. Laszewski","doi":"10.1145/1217728.1217739","DOIUrl":"https://doi.org/10.1145/1217728.1217739","url":null,"abstract":"Research in proteomics has created two significant needs: the need for an accurate public database of empirically derived mass spectrum information and the need for managing the I/O and organization of mass spectrometry data in the form of files and structures. Lack of an empirically derived database limits the ability of proteomic researchers to identify and study proteins. Managing the I/O and organization of mass spectrometry data is often time-consuming due to the many fields that need to be set and retrieved. As a result, incompatibilities and inefficiencies are created by each programmer handling this in his or her own way. Until recently, storage space and computing power has been the limiting factor in developing tools to handle the vast amount of mass spectrometry information. Now the resources are available to store, organize, and analyze mass spectrometry information.The Illinois Bio-Grid Mass Spectrometry Database is a database of empirically derived tandem mass spectra of peptides created to provide researchers with an organized and searchable database of curated spectrum information to allow more accurate protein identification. The Mass Spectrometry I/O Project creates a framework that handles mass spectrometry data I/O and data organization, allowing researchers to concentrate on data analysis rather than I/O. In addition, the Mass Spectrometry I/O Project leverages several cross-platform and portability-enhancing technologies, allowing it to be utilized on a variety of hardware and operating systems.","PeriodicalId":429016,"journal":{"name":"ACM Crossroads","volume":"78 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114790812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
If you thought video game addiction was a joke, you need a wake-up call. Video game addiction is a form of non-substance abuse like gambling. Fisher [2], in 1994, reported on a study of addiction to arcade machines. Adolescents surveyed in the study were from a small community that relied on tourism, and arcade machines available for tourists were easily accessible to these teenagers. The researchers used pathological measures that were adapted from those used to identify gambling addiction in adults. The results of the study identified some adolescents that were "pathological players" and found that not only did they play a lot more, but also that they were spending their lunch money, borrowing, stealing, and selling their possessions to play.
{"title":"At a crossroads: video game addiction","authors":"P. Bach, C. Jordon","doi":"10.1145/1217728.1217730","DOIUrl":"https://doi.org/10.1145/1217728.1217730","url":null,"abstract":"If you thought video game addiction was a joke, you need a wake-up call. Video game addiction is a form of non-substance abuse like gambling. Fisher [2], in 1994, reported on a study of addiction to arcade machines. Adolescents surveyed in the study were from a small community that relied on tourism, and arcade machines available for tourists were easily accessible to these teenagers. The researchers used pathological measures that were adapted from those used to identify gambling addiction in adults. The results of the study identified some adolescents that were \"pathological players\" and found that not only did they play a lot more, but also that they were spending their lunch money, borrowing, stealing, and selling their possessions to play.","PeriodicalId":429016,"journal":{"name":"ACM Crossroads","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116598938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
So you want to play DVDs in your car, listen to thousands of songs without changing a CD, play Half-Life 2, browse the Internet, and you want a navigation system; but, you don't want to pay more than $400? Well, then you are just like me and what you need is a carputer! A carputer is reasonably simple to make; the hardest part is finding the motivation to start. My project began as a result of boredom in my high school automotives class, and a really great sale on power inverters at Wal-Mart. To start, I purchased a 5.6" LCD screen on eBay and a 350 watt power inverter. I installed the power inverter in the car, designed a custom in-dash plate to hold the screen (see Figure 1), and tested the setup with a Playstation 2. To my delight, everything worked flawlessly.
{"title":"Ultimate car entertainment systems: the carputer","authors":"Nick Datzov","doi":"10.1145/1217728.1217740","DOIUrl":"https://doi.org/10.1145/1217728.1217740","url":null,"abstract":"So you want to play DVDs in your car, listen to thousands of songs without changing a CD, play Half-Life 2, browse the Internet, and you want a navigation system; but, you don't want to pay more than $400? Well, then you are just like me and what you need is a carputer! A carputer is reasonably simple to make; the hardest part is finding the motivation to start. My project began as a result of boredom in my high school automotives class, and a really great sale on power inverters at Wal-Mart. To start, I purchased a 5.6\" LCD screen on eBay and a 350 watt power inverter. I installed the power inverter in the car, designed a custom in-dash plate to hold the screen (see Figure 1), and tested the setup with a Playstation 2. To my delight, everything worked flawlessly.","PeriodicalId":429016,"journal":{"name":"ACM Crossroads","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134293083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pierre Pontevia is the Chief Technical Officer at Kynogon SA (www.kynogon.com). Established in 2000 by Pierre and his partner, Jacques Gaubil, Kynogon provides the leading artificial intelligence middleware solution, Kynapse, to both the gaming and serious gaming industries. Kynapse 4.0 was released in June 2006. Kynogon recently opened a new office in Montreal, Canada. I sat down with Pierre in the company's Paris office to ask him about his career, Kynapse, and working at Kynogon.
Pierre Pontevia是Kynogon SA (www.kynogon.com)的首席技术官。Kynogon由Pierre和他的合伙人Jacques Gaubil于2000年创立，为游戏和严肃游戏行业提供领先的人工智能中间件解决方案Kynapse。Kynapse 4.0于2006年6月发布。Kynogon最近在加拿大蒙特利尔开设了一个新办事处。我在公司的巴黎办公室与Pierre坐下来，询问他的职业、Kynapse以及在Kynogon的工作。
{"title":"AI and the rise of gaming middleware: an interview with Pierre Pontevia of Kynogon","authors":"Audrey Christophory","doi":"10.1145/1217728.1217735","DOIUrl":"https://doi.org/10.1145/1217728.1217735","url":null,"abstract":"Pierre Pontevia is the Chief Technical Officer at Kynogon SA (www.kynogon.com). Established in 2000 by Pierre and his partner, Jacques Gaubil, Kynogon provides the leading artificial intelligence middleware solution, Kynapse, to both the gaming and serious gaming industries. Kynapse 4.0 was released in June 2006. Kynogon recently opened a new office in Montreal, Canada. I sat down with Pierre in the company's Paris office to ask him about his career, Kynapse, and working at Kynogon.","PeriodicalId":429016,"journal":{"name":"ACM Crossroads","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130954592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Today in our society, there are two obvious groups of people: one who are able to effectively use technology, and secondly who are not. Many articles and reports call these groups the “haves” and “havenots.” Unfortunately, a large proportion of the population in the United States does not have the technological abilities that have become essential in our day to day lives. We call this partitioning of our society the Digital Divide. Because of the increasing amount of technology that is becoming a part of our society and the complexity of IT, many people are not able to keep up with the changing world. Many people have been left behind and will never be able to benefit from the advantages that today's technology offers. This paper is an insight of getting more description in a very lucid style.
{"title":"The digital divide","authors":"S. Dyer","doi":"10.1145/1217728.1217731","DOIUrl":"https://doi.org/10.1145/1217728.1217731","url":null,"abstract":"Today in our society, there are two obvious groups of people: one who are able to effectively use technology, and secondly who are not. Many articles and reports call these groups the “haves” and “havenots.” Unfortunately, a large proportion of the population in the United States does not have the technological abilities that have become essential in our day to day lives. We call this partitioning of our society the Digital Divide. Because of the increasing amount of technology that is becoming a part of our society and the complexity of IT, many people are not able to keep up with the changing world. Many people have been left behind and will never be able to benefit from the advantages that today's technology offers. This paper is an insight of getting more description in a very lucid style.","PeriodicalId":429016,"journal":{"name":"ACM Crossroads","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115823244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Firaxis Games is a game geek's Shangri-La. The company's office takes up the top floor of a high-rise in Hunt Valley, Maryland and hosts a team of designers, artists, sound technicians, and producers who put together, as the company slogan goes, "Games That Stand the Test of Time," a design principle that comes from one of the company's founders, the gaming great and creator of the celebrated Civilization series, Sid Meier. Meier sits behind his office door like the godfather of computer gaming, working on what is currently described only as a "secret project."
{"title":"Interesting complexity: Sid Meier and the secrets of game design","authors":"Caio Camargo","doi":"10.1145/1217728.1217732","DOIUrl":"https://doi.org/10.1145/1217728.1217732","url":null,"abstract":"Firaxis Games is a game geek's Shangri-La. The company's office takes up the top floor of a high-rise in Hunt Valley, Maryland and hosts a team of designers, artists, sound technicians, and producers who put together, as the company slogan goes, \"Games That Stand the Test of Time,\" a design principle that comes from one of the company's founders, the gaming great and creator of the celebrated Civilization series, Sid Meier. Meier sits behind his office door like the godfather of computer gaming, working on what is currently described only as a \"secret project.\"","PeriodicalId":429016,"journal":{"name":"ACM Crossroads","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129212585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The Sims, the creation of game designer Will Wright, is the best selling computer video game series of all time. A recent addition to the franchise (produced by Maxis and Electronic Arts) is an expansion pack to The Sims 2 entitled Open for Business. For those not familiar with the concept of The Sims, it is a life simulator. You control a variety of simulated people (Sims) as they live, love, work, relax, and even go to the bathroom.
游戏设计师威尔·赖特的作品《模拟人生》是有史以来最畅销的电脑视频游戏系列。该系列(由Maxis和ea制作)最近又增加了一个名为《the Sims 2》的扩展包，名为《Open for Business》。对于那些不熟悉《模拟人生》概念的人来说，这是一款生活模拟器。你可以控制各种各样的模拟人物，让他们生活、恋爱、工作、放松，甚至上厕所。
{"title":"The Sims 2: open for business: lessons learned about business and life","authors":"Chris Dondanville","doi":"10.1145/1217728.1217736","DOIUrl":"https://doi.org/10.1145/1217728.1217736","url":null,"abstract":"The Sims, the creation of game designer Will Wright, is the best selling computer video game series of all time. A recent addition to the franchise (produced by Maxis and Electronic Arts) is an expansion pack to The Sims 2 entitled Open for Business. For those not familiar with the concept of The Sims, it is a life simulator. You control a variety of simulated people (Sims) as they live, love, work, relax, and even go to the bathroom.","PeriodicalId":429016,"journal":{"name":"ACM Crossroads","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127854765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bioinformatics is the interdisciplinary intersection of computing and the life sciences. The National Institute of Health [6] defines bioinformatics as the use of computer techniques to explore biological problems. As computers have become more mobile -evolving from mainframes to desktop workstations to laptop computers to personal digital assistants (PDAs) [3] such as Palm Pilots and Pocket PCs -so too has bioinformatics. Recently, Riikonen and colleagues [10] wrote a client-server interface reminiscent of a thin client application that enables Internet-connected PDAs to search bioinformatics databases. Advances in technology have also led to advances in the teaching of bioinformatics, which is now supported by mobile platforms including the "thinking tag" and the Palm Pilot [4, 7]. In this paper, we explore the use of a Pocket PC genetics participatory simulation, an activity that embeds the investigator in a life-size simulation, in studying computational evolutionary biology, with particular emphasis on its value as a teaching tool.
{"title":"Becoming a virtual organism to learn about genetics","authors":"Alexander Bick","doi":"10.1145/1217666.1217673","DOIUrl":"https://doi.org/10.1145/1217666.1217673","url":null,"abstract":"Bioinformatics is the interdisciplinary intersection of computing and the life sciences. The National Institute of Health [6] defines bioinformatics as the use of computer techniques to explore biological problems. As computers have become more mobile -evolving from mainframes to desktop workstations to laptop computers to personal digital assistants (PDAs) [3] such as Palm Pilots and Pocket PCs -so too has bioinformatics. Recently, Riikonen and colleagues [10] wrote a client-server interface reminiscent of a thin client application that enables Internet-connected PDAs to search bioinformatics databases. Advances in technology have also led to advances in the teaching of bioinformatics, which is now supported by mobile platforms including the \"thinking tag\" and the Palm Pilot [4, 7]. In this paper, we explore the use of a Pocket PC genetics participatory simulation, an activity that embeds the investigator in a life-size simulation, in studying computational evolutionary biology, with particular emphasis on its value as a teaching tool.","PeriodicalId":429016,"journal":{"name":"ACM Crossroads","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123205479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
DNA can be thought of as a four-letter alphabet with the symbols A, C, G, and T representing the four possible nucleotides: adenine, cytosine, guanine, and thymine. The genome of an organism is composed of a linear sequence of A, C, G, and T that can be decoded from an individual's chromosomes. For the human genome, this is on the order of 3.2 billion bases. Within a genome, special sets of instructions known as genes code for proteins that provide structural and functional properties. Inside of a gene-coding region, every three bases codes for an amino acid. Since there are four possibilities for each position (A, C, G, or T), there are 4 * 4 * 4 = 64 potential three-base patterns, or codons.
{"title":"Aligning DNA sequences using dynamic programming","authors":"E. Rouchka","doi":"10.1145/1217666.1217675","DOIUrl":"https://doi.org/10.1145/1217666.1217675","url":null,"abstract":"DNA can be thought of as a four-letter alphabet with the symbols A, C, G, and T representing the four possible nucleotides: adenine, cytosine, guanine, and thymine. The genome of an organism is composed of a linear sequence of A, C, G, and T that can be decoded from an individual's chromosomes. For the human genome, this is on the order of 3.2 billion bases. Within a genome, special sets of instructions known as genes code for proteins that provide structural and functional properties. Inside of a gene-coding region, every three bases codes for an amino acid. Since there are four possibilities for each position (A, C, G, or T), there are 4 * 4 * 4 = 64 potential three-base patterns, or codons.","PeriodicalId":429016,"journal":{"name":"ACM Crossroads","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130094552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ask a dozen Internet experts what the term Web 2.0 means, and you'll get a dozen different answers. Some say that Web 2.0 is a set of philosophies and practices that provide Web users with a deep and rich experience. Others say it's a new collection of applications and technologies that make it easier for people to find information and connect with one another online. A few journalists maintain that the term doesn't mean anything at all -it's just a marketing ploy used to hype social networking sites.
{"title":"What is web 2.0?","authors":"Daniel Lewis","doi":"10.1145/1217666.1217669","DOIUrl":"https://doi.org/10.1145/1217666.1217669","url":null,"abstract":"Ask a dozen Internet experts what the term Web 2.0 means, and you'll get a dozen different answers. Some say that Web 2.0 is a set of philosophies and practices that provide Web users with a deep and rich experience. Others say it's a new collection of applications and technologies that make it easier for people to find information and connect with one another online. A few journalists maintain that the term doesn't mean anything at all -it's just a marketing ploy used to hype social networking sites.","PeriodicalId":429016,"journal":{"name":"ACM Crossroads","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132817153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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