Yuliya V. Khokhlova, O. M. Lesnyak, O. Inamova, Marianna S. Petrova
Rheumatoid arthritis is a chronic inflammatory disease caused by genetic and environmental factors. Smoking is the one of the most important external risk factors for development rheumatoid arthritis, severity, rapid disease progression and an unsatisfactory response to treatment. This findings determines the importance of studying smoking among patients with rheumatoid arthritis to identify barriers to smoking cessation and factors contributing to tobacco cessation, as well as to develop specific smoking cessation programs.
{"title":"Smoking and rheumatoid arthritis","authors":"Yuliya V. Khokhlova, O. M. Lesnyak, O. Inamova, Marianna S. Petrova","doi":"10.17816/rfd625754","DOIUrl":"https://doi.org/10.17816/rfd625754","url":null,"abstract":"Rheumatoid arthritis is a chronic inflammatory disease caused by genetic and environmental factors. Smoking is the one of the most important external risk factors for development rheumatoid arthritis, severity, rapid disease progression and an unsatisfactory response to treatment. This findings determines the importance of studying smoking among patients with rheumatoid arthritis to identify barriers to smoking cessation and factors contributing to tobacco cessation, as well as to develop specific smoking cessation programs.","PeriodicalId":432054,"journal":{"name":"Russian Family Doctor","volume":" 35","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141832957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The textbook “Outpatient Therapy,” prepared by a team of authors under the guidance of professors O.Yu. Kuznetsova and E.V. Frolova, allows you to implement a competent approach to training the future primary health care doctors. The textbook complies with the Federal State Educational Standard of Higher Education. The book is written at a high scientific and methodological level, it is distinguished by a holistic approach to the coverage of the training material and the focus on the formation of both universal and general professional, and specialized professional competencies in the future doctor. The textbook is intended for students of medical faculties and can be used as the main educational literature in the discipline “Outpatient Therapy”.
{"title":"About the textbook “Outpatient Therapy” edited by professors O.Yu. Kuznetsova and E.V. Frolova","authors":"Y. Khovaeva","doi":"10.17816/rfd630707","DOIUrl":"https://doi.org/10.17816/rfd630707","url":null,"abstract":"The textbook “Outpatient Therapy,” prepared by a team of authors under the guidance of professors O.Yu. Kuznetsova and E.V. Frolova, allows you to implement a competent approach to training the future primary health care doctors. The textbook complies with the Federal State Educational Standard of Higher Education. The book is written at a high scientific and methodological level, it is distinguished by a holistic approach to the coverage of the training material and the focus on the formation of both universal and general professional, and specialized professional competencies in the future doctor. The textbook is intended for students of medical faculties and can be used as the main educational literature in the discipline “Outpatient Therapy”.","PeriodicalId":432054,"journal":{"name":"Russian Family Doctor","volume":" 59","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141833490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Y. Kuznetsova, M. Pokhaznikova, K. V. Ovakimyan, Rosa R. Fatkieva, Anna Yu. Goriaeva, Elena A. Andreeva, Laura D. Gevorgian
BACKGROUND: Taking into account the importance of quitting smoking of any nicotine-containing products by young people in various social groups, a comparative analysis of the prevalence of smoking tobacco and nicotine-containing products among students of medical and technical universities in St. Petersburg was carried out. AIM: To compare the prevalence and structure of consumption of tobacco and nicotine-containing products, as well as the smoking behavior of students at medical and technical universities. MATERIALS AND METHODS: A cross-sectional cross-sectional study of a random sample of student groups included 1,105 respondents. RESULTS: The prevalence of tobacco smoking among students at a technical university was 2 times higher than at a medical university (p 0.01). Cigarette smoking was also more often noted at the onset of smoking among engineering students and in their families (p 0.05). 17.2% of North-Western State Medical University named after I.I. Mechnikov students and 14.2% of Saint Petersburg Electrotechnical University “LETI” named after V.I. Ulyanov (Lenin) students consume nicotine-containing products. Men from the medical university smoke cigarettes significantly more often than women, or use nicotine-containing products, as well as a combination of both. No similar gender differences were found at the technical university. Female doctors used ES more often than women from a technical university at the beginning of smoking (p 0.05). Men at a medical university started using nicotine-containing products more often than women, considering them the least dangerous to health (p 0.05). The example of friends was the most common reason for starting smoking among respondents from both universities (43.9 and 30.8%, respectively). Common risk factors for smoking any product among students of North-Western State Medical University and LETI were boyfriend/girlfriend smoking, smoking among one’s immediate environment. Studying in senior years was a protective factor for girls at a medical university in comparison with students at a technical university (odds ratio 0.48). CONCLUSIONS: The data obtained on the lower prevalence of tobacco smoking among medical university students compared to technical students may indirectly indicate the latter’s insufficient knowledge about the harmful effects of tobacco smoking on the body. The high prevalence of nicotine-containing products consumption in universities of various fields of study and the lack of significant differences in the share of their consumers can also be interpreted as an underestimation of the health risks of new smoking products. This requires adjustments to educational programs in order to increase students’ awareness of the potential health hazards not only of smoking cigarettes, but also of using any nicotine-containing products.
{"title":"Comparative analysis of the prevalence of smoking and consumption of nicotine-containing products and their risk factors among students of medical and technical universities of Saint Petersburg based on data from the PROTECT study","authors":"O. Y. Kuznetsova, M. Pokhaznikova, K. V. Ovakimyan, Rosa R. Fatkieva, Anna Yu. Goriaeva, Elena A. Andreeva, Laura D. Gevorgian","doi":"10.17816/rfd631886","DOIUrl":"https://doi.org/10.17816/rfd631886","url":null,"abstract":"BACKGROUND: Taking into account the importance of quitting smoking of any nicotine-containing products by young people in various social groups, a comparative analysis of the prevalence of smoking tobacco and nicotine-containing products among students of medical and technical universities in St. Petersburg was carried out. \u0000AIM: To compare the prevalence and structure of consumption of tobacco and nicotine-containing products, as well as the smoking behavior of students at medical and technical universities. \u0000MATERIALS AND METHODS: A cross-sectional cross-sectional study of a random sample of student groups included 1,105 respondents. \u0000RESULTS: The prevalence of tobacco smoking among students at a technical university was 2 times higher than at a medical university (p 0.01). Cigarette smoking was also more often noted at the onset of smoking among engineering students and in their families (p 0.05). 17.2% of North-Western State Medical University named after I.I. Mechnikov students and 14.2% of Saint Petersburg Electrotechnical University “LETI” named after V.I. Ulyanov (Lenin) students consume nicotine-containing products. Men from the medical university smoke cigarettes significantly more often than women, or use nicotine-containing products, as well as a combination of both. No similar gender differences were found at the technical university. Female doctors used ES more often than women from a technical university at the beginning of smoking (p 0.05). Men at a medical university started using nicotine-containing products more often than women, considering them the least dangerous to health (p 0.05). The example of friends was the most common reason for starting smoking among respondents from both universities (43.9 and 30.8%, respectively). Common risk factors for smoking any product among students of North-Western State Medical University and LETI were boyfriend/girlfriend smoking, smoking among one’s immediate environment. Studying in senior years was a protective factor for girls at a medical university in comparison with students at a technical university (odds ratio 0.48). \u0000CONCLUSIONS: The data obtained on the lower prevalence of tobacco smoking among medical university students compared to technical students may indirectly indicate the latter’s insufficient knowledge about the harmful effects of tobacco smoking on the body. The high prevalence of nicotine-containing products consumption in universities of various fields of study and the lack of significant differences in the share of their consumers can also be interpreted as an underestimation of the health risks of new smoking products. This requires adjustments to educational programs in order to increase students’ awareness of the potential health hazards not only of smoking cigarettes, but also of using any nicotine-containing products.","PeriodicalId":432054,"journal":{"name":"Russian Family Doctor","volume":" 22","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141833075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G.S. Balasaniants, Sumbul Z. Abdrakhmanova, L. T. Gilmutdinova, I. R. Farkhshatov
BACKGROUND: The possibility of mutual aggravation of post-tuberculosis and post-COVID respiratory pathologies requires additional consideration. AIM: To study some subjective breathing parameters at patients with post-tuberculosis pulmonary residual changes after a new coronavirus infection recovering. MATERIALS AND METHODS: The study included two groups: the main group — 14 patients with cured pulmonary tuberculosis, who had recovered from a new coronavirus infection, a comparison group — 52 patients with post-tuberculosis changes non-sick new coronavirus infection who were admitted to the tuberculosis sanatorium “Glukhovskaya” in 2020–2021. The severity of shortness of breath using the Modified Medical Research Council (mMRC) and Borg scales was assessed upon admission to the sanatorium and a month later. Results: The mMRC scale was 1.5 ± 1.4 and 2.1 ± 0.2 and the Borg scale was 1.5 ± 1.4 and 2.9 ± 0.2 before treatment respectively in the main group and the comparison group. According to the mMRC scale initially 14.3 and 11.5% of patients with pulmonary tuberculosis and the comparison group did not complain of shortness of breath and 50% of pulmonary tuberculosis patients and 42.4% of the comparison group defined it as severe. After a month there were 3 or 4 points on the mMRC scale among pulmonary tuberculosis patients. In the comparison group 3-point shortness of breath decreased by 11.2 times most often indicated shortness of breath with 2 score. According to the Borg scale dyspnea was initially assessed as 3 points at 71.5% pulmonary tuberculosis patients. In the comparison group 67.3% patients had grade 3 dyspnea and 11.5% noted 4–6 grade shortness of breath. After a month the proportion of patients with mild shortness of breath at the pulmonary tuberculosis and comparison groups increased by 4.5 and 3.3 times, respectively, and the frequency of 3-grade shortness of breath decreased by 5 and 3.9 times. CONCLUSIONS: Major post-tuberculosis changes, smoking and chronic obstructive pulmonary disease determine the severity of breathing discomfort to a greater extent than the experience of new coronavirus infection but rehabilitation treatment are leveled out these differences. It is advisable to study the state of the respiratory system at patients cured of pulmonary tuberculosis.
{"title":"Breath assessment at with post-tuberculosis patients suffered new coronavirus infection","authors":"G.S. Balasaniants, Sumbul Z. Abdrakhmanova, L. T. Gilmutdinova, I. R. Farkhshatov","doi":"10.17816/rfd626940","DOIUrl":"https://doi.org/10.17816/rfd626940","url":null,"abstract":"BACKGROUND: The possibility of mutual aggravation of post-tuberculosis and post-COVID respiratory pathologies requires additional consideration. \u0000AIM: To study some subjective breathing parameters at patients with post-tuberculosis pulmonary residual changes after a new coronavirus infection recovering. \u0000MATERIALS AND METHODS: The study included two groups: the main group — 14 patients with cured pulmonary tuberculosis, who had recovered from a new coronavirus infection, a comparison group — 52 patients with post-tuberculosis changes non-sick new coronavirus infection who were admitted to the tuberculosis sanatorium “Glukhovskaya” in 2020–2021. The severity of shortness of breath using the Modified Medical Research Council (mMRC) and Borg scales was assessed upon admission to the sanatorium and a month later. \u0000Results: The mMRC scale was 1.5 ± 1.4 and 2.1 ± 0.2 and the Borg scale was 1.5 ± 1.4 and 2.9 ± 0.2 before treatment respectively in the main group and the comparison group. According to the mMRC scale initially 14.3 and 11.5% of patients with pulmonary tuberculosis and the comparison group did not complain of shortness of breath and 50% of pulmonary tuberculosis patients and 42.4% of the comparison group defined it as severe. After a month there were 3 or 4 points on the mMRC scale among pulmonary tuberculosis patients. In the comparison group 3-point shortness of breath decreased by 11.2 times most often indicated shortness of breath with 2 score. According to the Borg scale dyspnea was initially assessed as 3 points at 71.5% pulmonary tuberculosis patients. In the comparison group 67.3% patients had grade 3 dyspnea and 11.5% noted 4–6 grade shortness of breath. After a month the proportion of patients with mild shortness of breath at the pulmonary tuberculosis and comparison groups increased by 4.5 and 3.3 times, respectively, and the frequency of 3-grade shortness of breath decreased by 5 and 3.9 times. \u0000CONCLUSIONS: Major post-tuberculosis changes, smoking and chronic obstructive pulmonary disease determine the severity of breathing discomfort to a greater extent than the experience of new coronavirus infection but rehabilitation treatment are leveled out these differences. It is advisable to study the state of the respiratory system at patients cured of pulmonary tuberculosis.","PeriodicalId":432054,"journal":{"name":"Russian Family Doctor","volume":" 34","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141833476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Turusheva, Daria V. Pronina, Alla M. Shchukina, Victoria E. Lepa
BACKGROUND: High consumption of vegetables and fruits is associated with a reduced risk of developing cardiovascular diseases, type 2 diabetes mellitus, cancer and all — causes mortality. However, most studies on the health benefits of fruit and vegetable consumption have traditionally focused on children, adolescents, young and middle-aged people, and only a few of them included older adults, and even more so did not take into account the geriatric status of the study participants. AIM: To assess the effect of fruit and vegetable consumption on mortality in Russian population people 65 years and older. MATERIALS AND METHODS: A prospective cohort study of a random sample of individuals aged 65 years and older (n = 383). The main parameters of the study: Mini Nutritional Assessment anthropometry, clinical blood test, albumin, total protein, C-reactive protein, comprehensive geriatric assessment, 2.5 years of follow-up. RESULTS: The average age of the participants was 77.7 ± 5.7 years. The frequency of fruit and vegetable consumption was higher among women, compared with men by 16.7% (95% confidence interval 1.5–33.6%). Consumption of 2 or more portions vegetables and/or fruits per day was associated with a reduced risk of death from all causes with hazard ratio 0.401 (95% confidence interval 0.180–0.896) after adjusting for gender, age of study participants, presence of malnourishment syndrome, protein intake, glasses drunk per day, body mass index, reduced middle arm circumstance, falls, cognitive status, autonomy decline and a decrease in the level of physical function. CONCLUSIONS: Consumption of 2 or more portions of vegetables and/or fruits per day was independently associated with a 59.9% reduction in the risk of death from all causes in persons aged 65 years and older.
{"title":"The impact of vegetable and fruit consumption on mortality in persons aged 65 years and older: results of a prospective cohort study","authors":"A. Turusheva, Daria V. Pronina, Alla M. Shchukina, Victoria E. Lepa","doi":"10.17816/rfd631569","DOIUrl":"https://doi.org/10.17816/rfd631569","url":null,"abstract":"BACKGROUND: High consumption of vegetables and fruits is associated with a reduced risk of developing cardiovascular diseases, type 2 diabetes mellitus, cancer and all — causes mortality. However, most studies on the health benefits of fruit and vegetable consumption have traditionally focused on children, adolescents, young and middle-aged people, and only a few of them included older adults, and even more so did not take into account the geriatric status of the study participants. \u0000AIM: To assess the effect of fruit and vegetable consumption on mortality in Russian population people 65 years and older. \u0000MATERIALS AND METHODS: A prospective cohort study of a random sample of individuals aged 65 years and older (n = 383). The main parameters of the study: Mini Nutritional Assessment anthropometry, clinical blood test, albumin, total protein, C-reactive protein, comprehensive geriatric assessment, 2.5 years of follow-up. \u0000RESULTS: The average age of the participants was 77.7 ± 5.7 years. The frequency of fruit and vegetable consumption was higher among women, compared with men by 16.7% (95% confidence interval 1.5–33.6%). Consumption of 2 or more portions vegetables and/or fruits per day was associated with a reduced risk of death from all causes with hazard ratio 0.401 (95% confidence interval 0.180–0.896) after adjusting for gender, age of study participants, presence of malnourishment syndrome, protein intake, glasses drunk per day, body mass index, reduced middle arm circumstance, falls, cognitive status, autonomy decline and a decrease in the level of physical function. \u0000CONCLUSIONS: Consumption of 2 or more portions of vegetables and/or fruits per day was independently associated with a 59.9% reduction in the risk of death from all causes in persons aged 65 years and older.","PeriodicalId":432054,"journal":{"name":"Russian Family Doctor","volume":" 48","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141833205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The editorial board regret that in the published version of “Gorham–Stout disease started with recurrent bilateral exudative pleuritis: case description and literature review” institution (place of work) of the authors North-Western State Medical University named after I.I. Mechnikov was indicated incorrectly. The authors’ institutions are: Olga M. Lesnyak — North Western State Medical University named after I.I. Mechnikov, Clinical Rheumatological Hospital No. 25, Saint Petersburg; Vadim G. Pischik — Saint Petersburg State University, City Clinical Oncological Clinic, Saint Petersburg; Olga N. Tkach — Clinical Rheumatological Hospital No. 25, Saint Petersburg; Elena S. Kunitsina — Clinical Rheumatological Hospital No. 25, Saint Petersburg. The editorial board is confident that the error could not significantly affect the perception of the work and the interpretation of information by readers. The error has been corrected online, the file of the article and the issue have been updated.
编辑部感到遗憾的是，"Gorham-Stout 病起病于反复发作的双侧渗出性胸膜炎：病例描述和文献综述 "的出版版本中，以 I.I. Mechnikov 命名的西北国立医科大学的作者单位（工作单位）标注有误。作者单位为 Olga M. Lesnyak - 以 I.I. Mechnikov 命名的西北国立医科大学，圣彼得堡第 25 临床风湿病医院；Vadim G. Pischik - 圣彼得堡国立大学，圣彼得堡市临床肿瘤诊所；Olga N. Tkach - 圣彼得堡第 25 临床风湿病医院；Elena S. Kunitsina - 圣彼得堡第 25 临床风湿病医院。 编辑委员会相信，该错误不会对读者对作品的理解和信息的解读产生重大影响。该错误已在网上更正，文章文件和期刊也已更新。
{"title":"Erratum to “Gorham–Stout disease started with recurrent bilateral exudative pleuritis: case description and literature review” (doi: 10.17816/RFD625565)","authors":"","doi":"10.17816/rfd632468","DOIUrl":"https://doi.org/10.17816/rfd632468","url":null,"abstract":"The editorial board regret that in the published version of “Gorham–Stout disease started with recurrent bilateral exudative pleuritis: case description and literature review” institution (place of work) of the authors North-Western State Medical University named after I.I. Mechnikov was indicated incorrectly. \u0000The authors’ institutions are: \u0000 \u0000Olga M. Lesnyak — North Western State Medical University named after I.I. Mechnikov, Clinical Rheumatological Hospital No. 25, Saint Petersburg; \u0000Vadim G. Pischik — Saint Petersburg State University, City Clinical Oncological Clinic, Saint Petersburg; \u0000Olga N. Tkach — Clinical Rheumatological Hospital No. 25, Saint Petersburg; \u0000Elena S. Kunitsina — Clinical Rheumatological Hospital No. 25, Saint Petersburg. \u0000 \u0000The editorial board is confident that the error could not significantly affect the perception of the work and the interpretation of information by readers. The error has been corrected online, the file of the article and the issue have been updated.","PeriodicalId":432054,"journal":{"name":"Russian Family Doctor","volume":" 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141833527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vladimir A. Neverov, G. I. Kirpichnikova, Vsevolod M. Antonov, G. Startseva, Margarita V. Klur
The lecture is devoted to two infections controlled by specific means of prevention — measles and rubella, which still pose a danger both to the sphere of child and maternal health, and to healthcare in general. The second part of the lecture is devoted to rubella, which, despite its benign course in most cases, currently poses a serious problem for global health due to its ubiquity and high incidence of severe intrauterine lesions of the fetus. Despite significant advances in the field of diagnosis and immunoprophylaxis of rubella, it is still found in economically developed countries with confirmed elimination of the disease. Therefore, to prevent the return of this infection to our country, where its elimination was achieved by 2018, maximum coverage of the population with vaccinations against rubella is still necessary in all its regions. The lecture covers modern aspects of the etiopathogenesis, epidemiology, clinical picture, diagnosis, treatment and prevention of rubella. This information, given the increasing incidence of rubella, even in countries with confirmed elimination of the disease, may be useful for general practitioners, primarily family doctors.
{"title":"Measles and rubella are two controlled airborne infections: etiopathogenesis, epidemiology, clinical picture, diagnosis, treatment and prevention. Part 2. Rubella","authors":"Vladimir A. Neverov, G. I. Kirpichnikova, Vsevolod M. Antonov, G. Startseva, Margarita V. Klur","doi":"10.17816/rfd625359","DOIUrl":"https://doi.org/10.17816/rfd625359","url":null,"abstract":"The lecture is devoted to two infections controlled by specific means of prevention — measles and rubella, which still pose a danger both to the sphere of child and maternal health, and to healthcare in general. \u0000The second part of the lecture is devoted to rubella, which, despite its benign course in most cases, currently poses a serious problem for global health due to its ubiquity and high incidence of severe intrauterine lesions of the fetus. Despite significant advances in the field of diagnosis and immunoprophylaxis of rubella, it is still found in economically developed countries with confirmed elimination of the disease. Therefore, to prevent the return of this infection to our country, where its elimination was achieved by 2018, maximum coverage of the population with vaccinations against rubella is still necessary in all its regions. \u0000The lecture covers modern aspects of the etiopathogenesis, epidemiology, clinical picture, diagnosis, treatment and prevention of rubella. This information, given the increasing incidence of rubella, even in countries with confirmed elimination of the disease, may be useful for general practitioners, primarily family doctors.","PeriodicalId":432054,"journal":{"name":"Russian Family Doctor","volume":" 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141833035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lyudmila V. Tribuntceva, A. V. Budnevsky, G. G. Prozorova, I. Olysheva, R. A. Khokhlov
BACKGROUND: Despite significant progress in the search for treatable additional features affecting multicomponent control of bronchial asthma, there is currently a paucity of research studies with a comprehensive assessment of the impact of obesity and multimorbidity on quality of life in patients with bronchial asthma. AIM: To assess the effect of personalizing features (obesity and multimorbidity) on the quality of life of patients with different levels of asthma control. MATERIALS AND METHODS: Patients with asthma (n = 237) were divided into 3 groups depending on BMI. Multimorbid pathology was analyzed by Cumulative Illness Rating Scale (CIRS), asthma control — Asthma Control Questionnaire-5 (ACQ-5), quality of life — Asthma Quality of Life Questionnaire with Standardized Activities [AQLQ(S)], anxiety and depression — Hospital Anxiety and Depression Scale (HADS). Statistical analysis: Microsoft Excel, Statistica 12.0, Statgraphics XVIII. RESULTS: Patients with obesity and asthma had more comorbidities (p 0.05). Quality of life in patients with high and normal body weight depended on the level of control and the number of diseases (p 0.05), with getting worse disease control these differences became insignificant. In the group with obesity, activity limitation (p = 0.0150) and overall quality of life (p 0.005) increased significantly with increasing number of diseases. Anxiety levels increased with increasing number of illnesses (p 0.0001). Quality of life of patients according to AQLQ(S) has inverse correlation with BMI (r = −0.5135), age (r = −0.2034) with CIRS scores (r = −0.4905) with anxiety (r = −0.5078) and depression (r = −0.4820) level. CONCLUSIONS: Body weight, level of asthma control, depression and anxiety, and the number of comorbid multimorbid conditions affect the quality of life of patients with asthma. Obesity makes a significant negative contribution to worsening asthma control and patients’ quality of life, in this group patients have the highest level of multimorbidity and they have a prevalence of anxiety. To improve asthma control, patients need a complex examination including assessment of quality of life, depression and anxiety, and comorbidities in order to develop personalization of therapeutic approaches to patient management.
{"title":"Quality of life of patients with asthma: the effects of overweight, obesity and multimorbidity","authors":"Lyudmila V. Tribuntceva, A. V. Budnevsky, G. G. Prozorova, I. Olysheva, R. A. Khokhlov","doi":"10.17816/rfd627462","DOIUrl":"https://doi.org/10.17816/rfd627462","url":null,"abstract":"BACKGROUND: Despite significant progress in the search for treatable additional features affecting multicomponent control of bronchial asthma, there is currently a paucity of research studies with a comprehensive assessment of the impact of obesity and multimorbidity on quality of life in patients with bronchial asthma. \u0000AIM: To assess the effect of personalizing features (obesity and multimorbidity) on the quality of life of patients with different levels of asthma control. \u0000MATERIALS AND METHODS: Patients with asthma (n = 237) were divided into 3 groups depending on BMI. Multimorbid pathology was analyzed by Cumulative Illness Rating Scale (CIRS), asthma control — Asthma Control Questionnaire-5 (ACQ-5), quality of life — Asthma Quality of Life Questionnaire with Standardized Activities [AQLQ(S)], anxiety and depression — Hospital Anxiety and Depression Scale (HADS). Statistical analysis: Microsoft Excel, Statistica 12.0, Statgraphics XVIII. \u0000RESULTS: Patients with obesity and asthma had more comorbidities (p 0.05). Quality of life in patients with high and normal body weight depended on the level of control and the number of diseases (p 0.05), with getting worse disease control these differences became insignificant. In the group with obesity, activity limitation (p = 0.0150) and overall quality of life (p 0.005) increased significantly with increasing number of diseases. Anxiety levels increased with increasing number of illnesses (p 0.0001). Quality of life of patients according to AQLQ(S) has inverse correlation with BMI (r = −0.5135), age (r = −0.2034) with CIRS scores (r = −0.4905) with anxiety (r = −0.5078) and depression (r = −0.4820) level. \u0000CONCLUSIONS: Body weight, level of asthma control, depression and anxiety, and the number of comorbid multimorbid conditions affect the quality of life of patients with asthma. Obesity makes a significant negative contribution to worsening asthma control and patients’ quality of life, in this group patients have the highest level of multimorbidity and they have a prevalence of anxiety. To improve asthma control, patients need a complex examination including assessment of quality of life, depression and anxiety, and comorbidities in order to develop personalization of therapeutic approaches to patient management.","PeriodicalId":432054,"journal":{"name":"Russian Family Doctor","volume":" 52","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141833587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. M. Lesnyak, V. Pischik, Olga N. Tkach, Elena S. Kunitsina
Gorham–Stout disease is an extremely rare skeletal disorder of unknown etiology manifested by multiple foci of osteolysis (“vanishing bone disease”) and lymphangiomatosis. Osteolysis can occur in any part of the skeleton (skull, facial skeleton, ribs, clavicula, spine, pelvic bones, bones of the upper and lower extremities). Approximately half of the patients develop pleural effusion, accompanied by respiratory abnormalities. We describe a case of Gorham-Stout disease with recurrent bilateral exudative pleuritis as a first and most prominent sign, while the bone lesions at the vertebral bodies, ribs and sternum proceeded without active complaints and were an accidental finding during chest computer tomography. Timely diagnosis of the disease depends on the awareness of doctors of various specialties and careful reading of imaging results.
{"title":"Gorham–Stout disease started with recurrent bilateral exudative pleuritis: case description and literature review","authors":"O. M. Lesnyak, V. Pischik, Olga N. Tkach, Elena S. Kunitsina","doi":"10.17816/rfd625565","DOIUrl":"https://doi.org/10.17816/rfd625565","url":null,"abstract":"Gorham–Stout disease is an extremely rare skeletal disorder of unknown etiology manifested by multiple foci of osteolysis (“vanishing bone disease”) and lymphangiomatosis. Osteolysis can occur in any part of the skeleton (skull, facial skeleton, ribs, clavicula, spine, pelvic bones, bones of the upper and lower extremities). Approximately half of the patients develop pleural effusion, accompanied by respiratory abnormalities. We describe a case of Gorham-Stout disease with recurrent bilateral exudative pleuritis as a first and most prominent sign, while the bone lesions at the vertebral bodies, ribs and sternum proceeded without active complaints and were an accidental finding during chest computer tomography. Timely diagnosis of the disease depends on the awareness of doctors of various specialties and careful reading of imaging results.","PeriodicalId":432054,"journal":{"name":"Russian Family Doctor","volume":"30 32","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140358512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BACKGROUND: The FRAX calculator is an accessible method for identifying patients at high risk of fracture. However, data on its practical use in primary health care settings are limited. AIM: To evaluate the correctness of calculating the 10-year fracture probability according to FRAX by primary care physicians and then analyze the impact of the results on patient routing. MATERIALS AND METHODS: The base of the study was the city polyclinic No. 25 of the Nevsky district of Saint Petersburg. The study included men and women aged 40 years and older. During 2017–2020, polyclinic doctors assessed the risk of fracture using the FRAX calculator for 11,013 people. A group of patients with significant differences (30% or more) in the obtained value of the risk of major osteoporotic fractures from the average was identified. A 10-year probability of fractures was recalculated for these patients. RESULTS: Major osteoporotic fracture risk scores were compared before and after recalculation. In most cases of patients (83%), the risk category did not change after recalculation. In 15% of patients changed to a higher risk. In the total group (11,013 people), errors in FRAX calculation led to an underestimation of high fracture risk in 41 patients (0.4%). CONCLUSIONS: The study showed that primary care physicians use the FRAX calculator correctly. The proportion of incorrect fracture risk calculations was low. Nevertheless, training of primary care physicians in the calculation and interpretation of the FRAX score is essential.
{"title":"The role of the primary care physician in identifying patients at high risk of fractures in real clinical practice","authors":"E. Gladkova, Maria S. Seregina, Anna A. Soboleva","doi":"10.17816/rfd626717","DOIUrl":"https://doi.org/10.17816/rfd626717","url":null,"abstract":"BACKGROUND: The FRAX calculator is an accessible method for identifying patients at high risk of fracture. However, data on its practical use in primary health care settings are limited. \u0000AIM: To evaluate the correctness of calculating the 10-year fracture probability according to FRAX by primary care physicians and then analyze the impact of the results on patient routing. \u0000MATERIALS AND METHODS: The base of the study was the city polyclinic No. 25 of the Nevsky district of Saint Petersburg. The study included men and women aged 40 years and older. \u0000During 2017–2020, polyclinic doctors assessed the risk of fracture using the FRAX calculator for 11,013 people. A group of patients with significant differences (30% or more) in the obtained value of the risk of major osteoporotic fractures from the average was identified. A 10-year probability of fractures was recalculated for these patients. \u0000RESULTS: Major osteoporotic fracture risk scores were compared before and after recalculation. In most cases of patients (83%), the risk category did not change after recalculation. In 15% of patients changed to a higher risk. In the total group (11,013 people), errors in FRAX calculation led to an underestimation of high fracture risk in 41 patients (0.4%). \u0000CONCLUSIONS: The study showed that primary care physicians use the FRAX calculator correctly. The proportion of incorrect fracture risk calculations was low. Nevertheless, training of primary care physicians in the calculation and interpretation of the FRAX score is essential.","PeriodicalId":432054,"journal":{"name":"Russian Family Doctor","volume":"3 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140359456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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