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A novel use of growth factors, CD34 positive cells, and fibrin for fingertip injury: Description of a case 生长因子、CD34阳性细胞和纤维蛋白在指尖损伤中的新应用:一个病例的描述
IF 0.4 Q4 DERMATOLOGY Pub Date : 2016-01-01 DOI: 10.1016/j.jdds.2015.09.002
Francesco Romano , Barbara Andrea Rizzo , Luigi Sacco , Antonio Russo , Maria Teresa Paparo , Francesco Paolino , Andrea Dominijanni , Roberta Stefanelli , Stephen Southworth , Raffaele Serra , Luca Gallelli

Traumatic soft tissue injuries of the finger represent a frequent hand injury challenging hand surgeons. We report a case involving a 30-year-old man with a dorsal index finger soft tissue wound failing conservative treatment. The novel use of applied fibrin membranes and concentrated growth factors yielded complete resolution of the injury in 6 months without need for skin grafting.

手指外伤性软组织损伤是手外科医生面临的一种常见的手部损伤。我们报告一例涉及一个30岁的男子与背食指软组织伤口失败保守治疗。应用纤维蛋白膜和浓缩生长因子的新方法在6个月内完全解决了损伤,无需皮肤移植。
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引用次数: 2
Chemical burn following 50% trichloroacetic acid for acne: Presentation of a case and a focused review 50%三氯乙酸治疗痤疮后的化学烧伤:一个病例的介绍和重点综述
IF 0.4 Q4 DERMATOLOGY Pub Date : 2016-01-01 DOI: 10.1016/j.jdds.2015.06.001
Hannah Liu , Amor Khachemoune , Rashid M. Rashid

Background

Chemical peels are widely used minimally invasive procedures with both cosmetic and medical indications. Although known for their general safety and efficacy, peels can rarely result in significant complications.

Objective

Here we report the first case in the peer-reviewed literature of chemical burn from erroneous home use of 50% trichloroacetic acid.

Methods

A focused literature review was performed of complications relating to chemical peels.

Results

Chemical burns from trichloroacetic acid peels are rare. To our knowledge, this is the first such case reported with supporting histopathological data.

Conclusions

Physicians must be aware of the potential complications of chemical peels, prevention strategies, and treatment modalities.

化学换肤是广泛应用于美容和医学适应症的微创手术。虽然以其一般的安全性和有效性而闻名,但换肤很少会导致严重的并发症。目的报告同行评议文献中第一例因误用50%三氯乙酸而致化学烧伤的病例。方法对化学换肤术并发症的相关文献进行回顾性分析。结果三氯乙酸脱皮引起的化学烧伤少见。据我们所知,这是第一例有组织病理学数据支持的病例。结论医师必须了解化学换肤的潜在并发症、预防策略和治疗方法。
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引用次数: 4
Transformed dermatofibrosarcoma protuberans: A series of nine cases and literature review 转化性皮肤纤维肉瘤隆突:附九例报告并文献复习
IF 0.4 Q4 DERMATOLOGY Pub Date : 2016-01-01 DOI: 10.1016/j.jdds.2015.07.001
Leila Achouri, Amira Triki, Hatem Bouzaiene, Molka Chemleli, Boutheina Laamouri, Maher Slimen, Tarek Dhiab, Khaled Rahal

The fibrosarcomatous variant of dermatofibrosarcoma protuberans (DFSP) represents an uncommon form of DFSP which has a higher risk of local recurrence and distant metastases than ordinary DFSP.

The aim of our study is to investigate clinicopathologic characteristics, treatment modalities and prognostic factors of nine cases of transformed DFSP admitted in Salah Azaiez Institute between 2002 and 2009.

They were five men and four women. Median age at diagnosis was 52 years (35–87 years). The lesions were located on the abdominal wall (three cases), the upper limb (two cases), the back (two cases), the lower limb (one case) and the chest wall (one case). Tumor size ranged from 25 mm to 150 mm. After diagnosis, six patients were treated by wide local excision with margins ⩾2 cm, two patients had local excision without defined margins and one patient had incomplete local excision. Three patients underwent radiotherapy because of either cramped or unknown limits. Local recurrence was diagnosed in 5 cases and distant metastasis occurred in one patient.

Fibrosarcomatous DFSP exhibits more aggressive behavior than DFSP. Their similar clinical presentation requires histopathological differentiation for prognosis. Treatment is based on wide local excision, radiation and targeted therapy.

纤维肉瘤变体的皮肤纤维肉瘤隆突(DFSP)是一种罕见的DFSP形式,与普通的DFSP相比,它具有更高的局部复发和远处转移的风险。本研究旨在探讨Salah Azaiez研究所2002 - 2009年间收治的9例转化性DFSP的临床病理特征、治疗方式及预后因素。他们是五男四女。诊断时的中位年龄为52岁(35-87岁)。病变部位为腹壁(3例)、上肢(2例)、背部(2例)、下肢(1例)和胸壁(1例)。肿瘤大小从25mm到150mm不等。诊断后,6名患者接受边缘大于或等于2厘米的广泛局部切除治疗,2名患者进行了没有明确边缘的局部切除,1名患者进行了不完全局部切除。三名患者因狭窄或未知的限制而接受放疗。局部复发5例,远处转移1例。纤维肉瘤性DFSP表现出比DFSP更强的侵袭性行为。其相似的临床表现需要组织病理学的鉴别来判断预后。治疗的基础是广泛的局部切除,放射和靶向治疗。
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引用次数: 4
Nail-patella syndrome with infertility in a 38 year old Saudi male: A case report 38岁沙特男性甲髌骨综合征伴不孕症1例报告
IF 0.4 Q4 DERMATOLOGY Pub Date : 2016-01-01 DOI: 10.1016/j.jdds.2015.08.002
Nada Al-Ghamdi

Nail-patella syndrome (NPS) which also known as hereditary osteo-onychodysplasia is a rare autosomal-dominant disorder characterized by a classic clinical tetrad of changes in the nails, knees, elbows and the presence of iliac horns.

Occasionally the central nervous system, the eyes and the renal system are affected.

NPS was reported worldwide, affecting males and females equally.

Infertility was not mentioned in this syndrome before.

Here we are reporting a case of NPS in a 38 year old Saudi male, in association with infertility, which was exceptional and could represent an additional manifestation to the syndrome.

指甲-髌骨综合征(NPS),也被称为遗传性骨甲发育不良,是一种罕见的常染色体显性疾病,其典型的临床特征是指甲、膝盖、肘部和髂角的变化。偶尔中枢神经系统、眼睛和肾脏系统也会受到影响。全球都报告了NPS,对男性和女性的影响相同。不孕不育在此综合征中未被提及。在这里,我们报告一例38岁的沙特男性NPS,与不育症有关,这是例外的,可能是该综合征的另一种表现。
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引用次数: 0
Pattern of skin cancer at Dammam Medical Complex in Dammam, Saudi Arabia 沙特阿拉伯达曼达曼医疗中心皮肤癌的模式
IF 0.4 Q4 DERMATOLOGY Pub Date : 2016-01-01 DOI: 10.1016/j.jdds.2015.06.002
Khalid M. Alwunais , Sohail Ahmad

Objective

This study was performed to determine the pattern of skin malignancies in Dammam Medical Complex, Dammam, Kingdom of Saudi Arabia and to compare these results with those from other parts of the world.

Materials and methods

Histologically diagnosed skin cancers between June 2008 and May 2014 were reviewed and analyzed. Dammam Medical Complex is the main hospital in Dammam that receives most of the malignant cases in this area. Trends in incidence of skin cancers by their age, sex and anatomic location were examined.

Results

Of the 27 cases of skin cancer majority (74%) were Saudis and males (59.2%). The most common malignant skin lesion was BCC followed by SCC, dermatofibrosarcoma protuberans (DFSP), skin secondaries from stomach, breast and lung, mycosis fungoides (MF), malignant melanoma (MM). The most common site was head and neck for BCC, trunk for SCC, and trunk for DFSP.

Conclusion

Low occurrence of malignant skin tumors is found in dermatology practice in Dammam. Nevertheless BCC, SCC and MM should be considered in the dermatology practice locally.

The most common skin cancers seen are BCC and SCC followed by DFSB and MF. The site of distribution of BCC and SCC in our study is similar to studies from various other regions of Saudi Arabia and other countries.

目的本研究旨在确定沙特阿拉伯王国达曼达曼医疗中心皮肤恶性肿瘤的模式,并将这些结果与世界其他地区的结果进行比较。材料与方法回顾性分析2008年6月至2014年5月组织学诊断的皮肤癌病例。达曼综合医院是达曼的主要医院,接收了该地区大多数恶性病例。按年龄、性别和解剖位置检查皮肤癌发病率的趋势。结果27例皮肤癌患者中,沙特人占74%,男性占59.2%。最常见的恶性皮肤病变是BCC,其次是SCC、隆突性皮肤纤维肉瘤(DFSP)、胃、乳腺和肺部继发皮肤、蕈样真菌病(MF)、恶性黑色素瘤(MM)。BCC最常见的部位是头颈部,SCC最常见的部位是主干,DFSP最常见的部位是主干。结论达曼地区皮肤恶性肿瘤的发生率较低。然而,在当地的皮肤科实践中,BCC, SCC和MM应该被考虑。最常见的皮肤癌是BCC和SCC,其次是DFSB和MF。在我们的研究中,BCC和SCC的分布地点与沙特阿拉伯其他地区和其他国家的研究相似。
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引用次数: 9
Psoriasis: Correlation between severity index (PASI) and quality of life index (DLQI) based on the type of treatment 银屑病:基于治疗类型的严重程度指数(PASI)和生活质量指数(DLQI)的相关性
IF 0.4 Q4 DERMATOLOGY Pub Date : 2016-01-01 DOI: 10.1016/j.jdds.2015.05.002
Ali Al Raddadi , Abdulhadi Jfri , Sahal Samarghandi , Nesreen Matury , Taha Habibullah , Majed Alfarshoti , Ahmad Mahdi

Background

Psoriasis vulgaris is a common chronic dermatological disease that has a negative impact on the psychological status and the social interaction of the patient.

Objective

To correlate the quality of life and clinical severity of psoriasis vulgaris in patients using different types of treatment.

Materials and methods

This is a prospective observational cross-sectional study that took place over a 4 month period, from January to April 2014, at the King Abdul Aziz Medical City, Jeddah, Saudi Arabia. All patients with psoriasis vulgaris attending the dermatology clinics during this period were included.

Results

Of the total 41 Saudi patients, 25 were males and 16 were females. 21 were on combined (i.e. topical with either systemic or NB-UVB) and 20 were on topical treatments only. PASI score was moderate in the majority for both groups, that is, patients on topical (70%) and combined treatment (80%). DLQI score shows only a small effect on the patient’s quality of life for the majority (14/20) in the topical group and (16/21) for those on combined therapy.

Conclusion

There is no significant difference in terms of the effect of the type of treatment between the two groups.

背景寻常型牛皮癣是一种常见的慢性皮肤病,对患者的心理状态和社会交往产生负面影响。目的探讨不同治疗方式对寻常型银屑病患者生活质量和临床严重程度的影响。材料和方法这是一项前瞻性观察性横断面研究,于2014年1月至4月在沙特阿拉伯吉达的阿卜杜勒·阿齐兹国王医疗城进行,为期4个月。在此期间,所有在皮肤科诊所就诊的寻常型牛皮癣患者均被纳入研究。结果41例沙特患者中,男性25例,女性16例。21名患者接受了联合治疗(即局部使用全身或NB-UVB), 20名患者仅接受局部治疗。两组的PASI评分大多数为中等,即局部治疗(70%)和联合治疗(80%)的患者。DLQI评分对大多数局部治疗组(14/20)和联合治疗组(16/21)患者的生活质量只有很小的影响。结论两组在治疗方式的效果上无显著差异。
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引用次数: 16
Intralesional 8.33% Rifamycin infiltration; New treatment for cutaneous leishmaniasis 皮肤内利福霉素浸润8.33%;皮肤利什曼病的新疗法
IF 0.4 Q4 DERMATOLOGY Pub Date : 2016-01-01 DOI: 10.1016/j.jdds.2015.11.001
Nameer K. Al-Sudany , Yousif J. Ali
<div><h3>Background</h3><p>Cutaneous leishmaniasis (CL) is an endemic disease in Iraq, for which many therapies had been tried, aiming to induce cure with no or minimal scaring. Rifamycin is an antibacterial agent, with the ability to inhibit bacterial DNA-dependent RNA synthesis and it is effective against extra- and intracellular microorganisms.</p></div><div><h3>Objective</h3><p>To evaluate the effectiveness and safety of intralesional 8.33% Rifamycin infiltration in treatment of cutaneous leishmaniasis.</p></div><div><h3>Patients and methods</h3><p>This is an open controlled therapeutic trial, carried out in the outpatient clinic of Dermatology & Venereology, Al-Yarmouk Teaching Hospital during the period between the first of December 2013 to the end of June 2014. A total of 29 patients have been enrolled in this therapeutic trial, however 4 patients were defaulted and 25 patients have completed the therapeutic trial. Fourteen (56%) were males and 11 (44%) were females, with a male to female ratio 1.27. Their ages ranged from 6 to 60<!--> <!-->years, with a mean<!--> <!-->±<!--> <!-->SD of 28.6<!--> <!-->±<!--> <!-->14.9<!--> <!-->years. The total number of lesions was 56 and the duration of lesions ranged between 4 and 18<!--> <!-->weeks with a mean<!--> <!-->±<!--> <!-->SD of 9.9<!--> <!-->±<!--> <!-->4.4<!--> <!-->weeks. The size of lesions ranged from 0.5 to 6<!--> <!-->cm in diameter with a mean<!--> <!-->±<!--> <!-->SD of 2.46<!--> <!-->±<!--> <!-->1.17<!--> <!-->cm. All patients have been diagnosed through history and clinical examination and the diagnosis was confirmed by skin smear and biopsy. The lesions were divided into two groups; <strong><em>group A</em></strong> treated with intralesional 8.33% Rifamycin infiltration every 2<!--> <!-->weeks for a maximum of 5 sessions, while <strong><em>group B</em></strong> was left untreated as a control group. Follow up was every 2<!--> <!-->weeks during the treatment period, and for 6<!--> <!-->weeks after completing the therapeutic sessions.</p></div><div><h3>Results</h3><p>Twenty five patients with a total of 56 lesions were completed the study period. Twenty one (37%) lesions were ulcerative and 35 (63%) were non ulcerative lesions. Ten (40%) patients had single lesion whereas 15 (60%) patients had multiple lesions. In group A, 38 (92.7%) out of 41 lesions showed a cure with 2–5 sessions with a mean<!--> <!-->±<!--> <!-->SD of 4.9<!--> <!-->±<!--> <!-->0.79 sessions, while in the control group no lesion had significantly improved or cured. At the end of the study period, only 8 out of 41 treated lesions have left trivial scars. Most of the lesions showed transient hyperpigmentation at the end of the study, but fortunately, it had disappeared in all cases few weeks later.</p></div><div><h3>Conclusion</h3><p>Rifamycin 8.33% solution given intralesionally in cutaneous leishmaniasis is a highly effective agent with a success rate of 92.7%. For cure, it needs 2–5 local infiltrations given
皮肤利什曼病(CL)是伊拉克的一种地方病,已经尝试了许多治疗方法,目的是在没有惊吓或惊吓最小的情况下诱导治愈。利福霉素是一种抗菌剂,具有抑制细菌dna依赖性RNA合成的能力,对细胞外和细胞内微生物有效。目的评价8.33%利福霉素局部浸润治疗皮肤利什曼病的有效性和安全性。患者和方法:这是一项开放对照治疗试验,在皮肤科门诊进行;在2013年12月1日至2014年6月底期间,在Al-Yarmouk教学医院的性病科。本次治疗性试验共入组29例患者,有4例患者未入组,25例患者已完成治疗性试验。男性14例(56%),女性11例(44%),男女比例1.27。年龄6 ~ 60岁,平均±SD 28.6±14.9岁。病灶总数56个,病灶持续时间4 ~ 18周,平均±SD为9.9±4.4周。病灶直径0.5 ~ 6cm,平均±SD为2.46±1.17 cm。所有患者均通过病史和临床检查确诊,并经皮肤涂片和活检确诊。病变分为两组;A组以8.33%利福霉素局部浸润治疗,每2周治疗一次,最多5次;B组不治疗,作为对照组。治疗期间每2周随访一次,治疗结束后随访6周。结果25例患者共56个病灶完成了研究。溃疡性病变21例(37%),非溃疡性病变35例(63%)。10例(40%)患者有单个病变,15例(60%)患者有多个病变。在A组中,41个病灶中有38个(92.7%)在2-5个疗程内治愈,平均±SD为4.9±0.79个疗程,而在对照组中,没有病灶明显改善或治愈。在研究期结束时,41个治疗病灶中只有8个留下了轻微的疤痕。大多数病变在研究结束时表现出短暂的色素沉着,但幸运的是,几周后所有病例的色素沉着都消失了。结论利福霉素8.33%溶液局部注射治疗皮肤利什曼病疗效显著,治愈率为92.7%。为了治愈,需要每两周进行2-5次局部浸润。除了有效之外,它还是皮肤利什曼病的一种安全且成本较低的治疗选择。
{"title":"Intralesional 8.33% Rifamycin infiltration; New treatment for cutaneous leishmaniasis","authors":"Nameer K. Al-Sudany ,&nbsp;Yousif J. Ali","doi":"10.1016/j.jdds.2015.11.001","DOIUrl":"10.1016/j.jdds.2015.11.001","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;p&gt;Cutaneous leishmaniasis (CL) is an endemic disease in Iraq, for which many therapies had been tried, aiming to induce cure with no or minimal scaring. Rifamycin is an antibacterial agent, with the ability to inhibit bacterial DNA-dependent RNA synthesis and it is effective against extra- and intracellular microorganisms.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Objective&lt;/h3&gt;&lt;p&gt;To evaluate the effectiveness and safety of intralesional 8.33% Rifamycin infiltration in treatment of cutaneous leishmaniasis.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Patients and methods&lt;/h3&gt;&lt;p&gt;This is an open controlled therapeutic trial, carried out in the outpatient clinic of Dermatology &amp; Venereology, Al-Yarmouk Teaching Hospital during the period between the first of December 2013 to the end of June 2014. A total of 29 patients have been enrolled in this therapeutic trial, however 4 patients were defaulted and 25 patients have completed the therapeutic trial. Fourteen (56%) were males and 11 (44%) were females, with a male to female ratio 1.27. Their ages ranged from 6 to 60&lt;!--&gt; &lt;!--&gt;years, with a mean&lt;!--&gt; &lt;!--&gt;±&lt;!--&gt; &lt;!--&gt;SD of 28.6&lt;!--&gt; &lt;!--&gt;±&lt;!--&gt; &lt;!--&gt;14.9&lt;!--&gt; &lt;!--&gt;years. The total number of lesions was 56 and the duration of lesions ranged between 4 and 18&lt;!--&gt; &lt;!--&gt;weeks with a mean&lt;!--&gt; &lt;!--&gt;±&lt;!--&gt; &lt;!--&gt;SD of 9.9&lt;!--&gt; &lt;!--&gt;±&lt;!--&gt; &lt;!--&gt;4.4&lt;!--&gt; &lt;!--&gt;weeks. The size of lesions ranged from 0.5 to 6&lt;!--&gt; &lt;!--&gt;cm in diameter with a mean&lt;!--&gt; &lt;!--&gt;±&lt;!--&gt; &lt;!--&gt;SD of 2.46&lt;!--&gt; &lt;!--&gt;±&lt;!--&gt; &lt;!--&gt;1.17&lt;!--&gt; &lt;!--&gt;cm. All patients have been diagnosed through history and clinical examination and the diagnosis was confirmed by skin smear and biopsy. The lesions were divided into two groups; &lt;strong&gt;&lt;em&gt;group A&lt;/em&gt;&lt;/strong&gt; treated with intralesional 8.33% Rifamycin infiltration every 2&lt;!--&gt; &lt;!--&gt;weeks for a maximum of 5 sessions, while &lt;strong&gt;&lt;em&gt;group B&lt;/em&gt;&lt;/strong&gt; was left untreated as a control group. Follow up was every 2&lt;!--&gt; &lt;!--&gt;weeks during the treatment period, and for 6&lt;!--&gt; &lt;!--&gt;weeks after completing the therapeutic sessions.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;p&gt;Twenty five patients with a total of 56 lesions were completed the study period. Twenty one (37%) lesions were ulcerative and 35 (63%) were non ulcerative lesions. Ten (40%) patients had single lesion whereas 15 (60%) patients had multiple lesions. In group A, 38 (92.7%) out of 41 lesions showed a cure with 2–5 sessions with a mean&lt;!--&gt; &lt;!--&gt;±&lt;!--&gt; &lt;!--&gt;SD of 4.9&lt;!--&gt; &lt;!--&gt;±&lt;!--&gt; &lt;!--&gt;0.79 sessions, while in the control group no lesion had significantly improved or cured. At the end of the study period, only 8 out of 41 treated lesions have left trivial scars. Most of the lesions showed transient hyperpigmentation at the end of the study, but fortunately, it had disappeared in all cases few weeks later.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusion&lt;/h3&gt;&lt;p&gt;Rifamycin 8.33% solution given intralesionally in cutaneous leishmaniasis is a highly effective agent with a success rate of 92.7%. For cure, it needs 2–5 local infiltrations given","PeriodicalId":43409,"journal":{"name":"Journal of Dermatology & Dermatologic Surgery-JDDS","volume":"20 1","pages":"Pages 39-45"},"PeriodicalIF":0.4,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jdds.2015.11.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81823170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Diffuse intramuscular lipoma responsible for monomelic hypertrophy 引起单细胞肥大的弥漫性肌内脂肪瘤
IF 0.4 Q4 DERMATOLOGY Pub Date : 2016-01-01 DOI: 10.1016/j.jdds.2015.07.005
Krich Sanaa , Meziane Mariame , Amraoui Nissrine , Abid Hatim , Mrini Abdelmajid , Tizniti Siham , Mernissi Fatima Zahra

Background

Lipomas are common benign soft tissue, however intramuscular lipoma, is an often misdiagnosed clinical entity. The aim of this case is to present an atypical infiltrating lipoma and discuss its diagnostic and therapeutic features.

Clinical features

A 24 year-old patient presented to our consultation with a swelling of the right lower limb from childhood and gradually increasing in size. Clinical examination revealed a firm and extended swelling along the leg, thigh and foot giving an aspect of monomelic hypertrophy. There were no signs of vascular or nerve compression.

Intervention and outcome

Pathological study showed a lipoma. Magnetic resonance imaging (MRI) of the right lower limb objectified a large infiltrating lipoma affecting muscles of the posterior compartment of the thigh and the right leg with no signs of malignancy. The diagnosis of intramuscular lipoma was done. The surgery was proposed but the patient refused.

Conclusion

This case report described an adult female patient with an unusually intramuscular lipoma where magnetic resonance imaging was playing an important role in the diagnostic. Indeed the intramuscular is a benign fatty tumor with characteristic appearance on MRI. Its management should be considered in multidisciplinary collaboration.

背景:脂肪瘤是常见的良性软组织,然而肌内脂肪瘤是一种常被误诊的临床实体。本病例的目的是提出一个不典型浸润性脂肪瘤,并讨论其诊断和治疗特点。临床特征:一名24岁的患者,从小右下肢肿胀,逐渐增大。临床检查显示沿腿部、大腿和足部有坚实和延伸的肿胀,表现为单核细胞肥大。没有血管或神经压迫的迹象。干预措施及结果:病理检查显示脂肪瘤。右下肢磁共振成像(MRI)显示一巨大浸润性脂肪瘤,影响大腿后腔室和右腿肌肉,无恶性体征。诊断为肌内脂肪瘤。建议做手术,但病人拒绝了。结论本病例报告描述了一例成年女性肌肉内脂肪瘤的异常,磁共振成像在诊断中发挥了重要作用。事实上,肌内是一种良性脂肪瘤,在MRI上具有特征性表现。其管理应在多学科合作中加以考虑。
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引用次数: 2
Comparative study between intralesional injection of bleomycin and 5-fluorouracil in the treatment of keloids and hypertrophic scars 局部注射博来霉素与5-氟尿嘧啶治疗瘢痕疙瘩和增生性瘢痕的比较研究
IF 0.4 Q4 DERMATOLOGY Pub Date : 2016-01-01 DOI: 10.1016/j.jdds.2015.07.003
Ahmed M. Kabel , Hanan H. Sabry , Neveen E. Sorour , Fatma M. Moharm

The aim of this work was to evaluate the efficacy and safety of intralesional injection of 5-fluorouracil and bleomycin in the treatment of keloids and hypertrophic scars. One hundred and twenty patients were divided into the following groups: group IA was injected intralesionally with 5-fluorouracil; group IB was injected intralesionally with a combination of triamcinolone acetonide and 5-fluorouracil; group II was injected intralesionally with bleomycin. Patients underwent follow up by photographing and Vancouver scar scale system. There was a significant improvement in the Vancouver scar scale in group II compared to group I after treatment. There was hyperpigmentation, pain and ulceration in all the studied groups. Pain was significantly decreased in group IB compared to that in group IA, ulceration was significantly decreased in group II than in group I while pain after injection was increased in group II than in group I. Relapse occurred in 12 patients of group IA, 14 patients of group IB and no relapse occurred in group II. So, intralesional injection of bleomycin was more effective and better in remission than intralesional 5-fluorouracil injection in the treatment of keloids and hypertrophic scars regardless of patient’s age, sex, disease duration or site of the lesion.

本研究的目的是评价5-氟尿嘧啶和博来霉素局部注射治疗瘢痕疙瘩和增生性疤痕的疗效和安全性。120例患者分为以下两组:IA组局部注射5-氟尿嘧啶;IB组局部注射曲安奈德联合5-氟尿嘧啶;II组局部注射博来霉素。随访采用摄影和温哥华疤痕评分法。治疗后,II组温哥华疤痕评分较I组有显著改善。所有研究组均出现色素沉着、疼痛和溃疡。IB组疼痛较IA组明显减轻,II组溃疡较I组明显减轻,II组注射后疼痛较I组加重。IA组12例复发,IB组14例,II组无复发。因此,无论患者的年龄、性别、病程或病变部位如何,病灶内注射博来霉素治疗瘢痕瘤和增生性瘢痕比病灶内注射5-氟尿嘧啶更有效,缓解效果更好。
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引用次数: 15
Scleredema diabeticorum – A case report 糖尿病硬化性水肿1例
IF 0.4 Q4 DERMATOLOGY Pub Date : 2015-07-01 DOI: 10.1016/j.jdds.2014.03.003
O.I. Ezejiofor , O. Onayemi , O.A. Olasode , R.T. Ikem , A.A. Komolafe , I.F. Ezejiofor

Scleredema, a medical problem first described by Buschke in 1902, is a rare scleromatosis of unknown aetiology, which is characterized by wooden, nonpitting induration of the skin. This skin disorder first affects the neck and face and may symmetrically spread to the shoulders, trunk, arms, and legs. We report a case of a 65 year-old hypertensive and diabetic male who presented with marked thickening of the upper back with obvious peau d’orange changes. Association with other complications of diabetes is not certain and treatment is difficult, though improvement is possible with optimal glycaemic control. Scleredema diabeticorum is rare and is a cause of significant morbidity in diabetes.

硬化症是一种病因不明的罕见硬化症,由Buschke于1902年首次描述,其特征是皮肤出现木质、无凹点硬化。这种皮肤病首先影响颈部和面部,并可能对称地扩散到肩部、躯干、手臂和腿部。我们报告一个65岁男性高血压和糖尿病的病例,他表现出明显的上背部增厚和明显的橙皮变化。与糖尿病其他并发症的关联尚不确定,治疗困难,但最佳血糖控制可能改善。糖尿病硬化性水肿是罕见的,是一个显著的发病率在糖尿病的原因。
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引用次数: 1
期刊
Journal of Dermatology & Dermatologic Surgery-JDDS
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