首页 > 最新文献

Proceedings of the Workshop on Mathematical Methods in Biomedical Image Analysis最新文献

英文 中文
Contour/surface registration using a physically deformable model 使用物理可变形模型的轮廓/表面配准
Pub Date : 1996-06-21 DOI: 10.1109/MMBIA.1996.534063
J. Qian, T. Mitsa, E. Hoffman
Describes a new approach of surface/contour registration based on a physically deformable model. No prior knowledge about the types of geometric transformation is required for registration. Instead, the authors' approach views the surface as made of elastic material that will change shape in response to the applied external force. The registration of two surfaces/contours is the deformation process of one shape towards the other governed by physical laws. Before the deformation, the two shapes are roughly registered with a global affine transformation. The physically deformable model is then applied to deform one shape to match the other. The point correspondences between the two shapes are established when one shape is finally deformed to the other. In the 2D case, the model is similar to the active contour model but registration is formulated as an equilibrium problem instead of minimization problem. The result is a set of decoupled linear system equations that are easy to solve. It is also shown that, because of physical constraints imposed the authors' model is an improved version of Burr's (1981) dynamic contour model. Experimental results are presented to demonstrate the performance of the model.
描述了一种基于物理可变形模型的曲面/轮廓配准新方法。注册时不需要预先了解几何变换的类型。相反,作者的方法将表面看作是由弹性材料制成的,它会根据施加的外力而改变形状。两个曲面/轮廓的配准是一个形状向另一个形状受物理规律支配的变形过程。变形前,用全局仿射变换对两个形状进行粗略配准。然后应用物理可变形模型来变形一个形状以匹配另一个形状。当一个形状最终变形为另一个形状时,两个形状之间的点对应关系就建立起来了。在二维情况下,该模型类似于活动轮廓模型,但配准被表述为平衡问题而不是最小化问题。结果是一组解耦的线性系统方程,易于求解。还表明,由于物理约束,作者的模型是Burr(1981)动态轮廓模型的改进版本。实验结果验证了该模型的有效性。
{"title":"Contour/surface registration using a physically deformable model","authors":"J. Qian, T. Mitsa, E. Hoffman","doi":"10.1109/MMBIA.1996.534063","DOIUrl":"https://doi.org/10.1109/MMBIA.1996.534063","url":null,"abstract":"Describes a new approach of surface/contour registration based on a physically deformable model. No prior knowledge about the types of geometric transformation is required for registration. Instead, the authors' approach views the surface as made of elastic material that will change shape in response to the applied external force. The registration of two surfaces/contours is the deformation process of one shape towards the other governed by physical laws. Before the deformation, the two shapes are roughly registered with a global affine transformation. The physically deformable model is then applied to deform one shape to match the other. The point correspondences between the two shapes are established when one shape is finally deformed to the other. In the 2D case, the model is similar to the active contour model but registration is formulated as an equilibrium problem instead of minimization problem. The result is a set of decoupled linear system equations that are easy to solve. It is also shown that, because of physical constraints imposed the authors' model is an improved version of Burr's (1981) dynamic contour model. Experimental results are presented to demonstrate the performance of the model.","PeriodicalId":436387,"journal":{"name":"Proceedings of the Workshop on Mathematical Methods in Biomedical Image Analysis","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1996-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128430644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Nonlinear registration of brain images using deformable models 使用可变形模型的脑图像非线性配准
Pub Date : 1996-06-21 DOI: 10.1109/MMBIA.1996.534061
C. Davatzikos
A key issue in several brain imaging applications, including computer aided neurosurgery, functional image analysis, and morphometrics, is the spatial normalization and registration of tomographic images from different subjects. This paper proposes a technique for spatial normalization of brain images based on elastically deformable models. In the authors' approach they use a deformable surface algorithm to find a parametric representation of the outer cortical surface and then use this representation to obtain a map between corresponding regions of the outer cortex in two different images. Based on the resulting map, the authors then derive a three-dimensional elastic warping transformation which brings two images in register. This transformation models images as inhomogeneous elastic objects which are deformed into registration with each other by external force fields. The elastic properties of the images can vary from one region to the other, allowing more variable brain regions, such as the ventricles, to deform more freely than less variable ones. Finally, the authors use prestrained elasticity to model structural irregularities, and in particular the ventricular expansion occurring with aging or diseases. The performance of the authors' algorithm is demonstrated on magnetic resonance images.
在一些脑成像应用中,包括计算机辅助神经外科、功能图像分析和形态计量学,一个关键问题是来自不同主体的断层图像的空间归一化和配准。提出了一种基于弹性变形模型的脑图像空间归一化技术。在作者的方法中,他们使用一种可变形表面算法来找到外皮层表面的参数表示,然后使用这种表示来获得两幅不同图像中外皮层相应区域之间的映射。在此基础上,作者推导出一种三维弹性扭曲变换,将两幅图像进行配准。这种变换将图像建模为非均匀的弹性物体,这些物体在外力作用下变形成相互配准的形状。图像的弹性属性可以从一个区域变化到另一个区域,允许更多可变的大脑区域,如脑室,比变化较小的区域更自由地变形。最后,作者使用预紧弹性来模拟结构不规则,特别是随着衰老或疾病而发生的心室扩张。在磁共振图像上验证了算法的性能。
{"title":"Nonlinear registration of brain images using deformable models","authors":"C. Davatzikos","doi":"10.1109/MMBIA.1996.534061","DOIUrl":"https://doi.org/10.1109/MMBIA.1996.534061","url":null,"abstract":"A key issue in several brain imaging applications, including computer aided neurosurgery, functional image analysis, and morphometrics, is the spatial normalization and registration of tomographic images from different subjects. This paper proposes a technique for spatial normalization of brain images based on elastically deformable models. In the authors' approach they use a deformable surface algorithm to find a parametric representation of the outer cortical surface and then use this representation to obtain a map between corresponding regions of the outer cortex in two different images. Based on the resulting map, the authors then derive a three-dimensional elastic warping transformation which brings two images in register. This transformation models images as inhomogeneous elastic objects which are deformed into registration with each other by external force fields. The elastic properties of the images can vary from one region to the other, allowing more variable brain regions, such as the ventricles, to deform more freely than less variable ones. Finally, the authors use prestrained elasticity to model structural irregularities, and in particular the ventricular expansion occurring with aging or diseases. The performance of the authors' algorithm is demonstrated on magnetic resonance images.","PeriodicalId":436387,"journal":{"name":"Proceedings of the Workshop on Mathematical Methods in Biomedical Image Analysis","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1996-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130778940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 49
An integrated approach for surface finding in medical images 医学图像表面发现的集成方法
Pub Date : 1996-06-21 DOI: 10.1109/MMBIA.1996.534077
A. Chakraborty, L. Staib, J. Duncan
The wide availability of three-dimensional medical images has made their direct analysis a necessity. Accurately segmenting and quantifying structures is a key issue for such images. Conventional gradient-based surface finding however often suffers from a variety of limitations. This paper proposes a surface finding approach that uses in addition to gradient information, region information. This makes the resulting procedure more robust to noise and improper initialization. It uses Gauss's Divergence theorem to find the surface of of a homogeneous region-classified area in the image and integrates this with a gray level gradient-based surface finder. Experimental results show that indeed, as expected, a significant improvement is achieved as a consequence of the use of this extra information. Further these improvements are achieved with little increase in computational overhead, an advantage derived from the application of Gauss's Divergence theorem.
三维医学图像的广泛可用性使得对其进行直接分析成为必要。准确分割和量化结构是这类图像的关键问题。然而,传统的基于梯度的表面探测常常受到各种各样的限制。本文提出了一种除了利用梯度信息外,还利用区域信息的曲面查找方法。这使得生成的过程对噪声和不正确的初始化更加健壮。该算法利用高斯散度定理在图像中寻找均匀区域分类区域的表面,并将其与基于灰度梯度的表面检测器相结合。实验结果表明,正如预期的那样,使用这些额外信息确实取得了显著的改进。此外,这些改进是在计算开销很少增加的情况下实现的,这是高斯散度定理应用的优势。
{"title":"An integrated approach for surface finding in medical images","authors":"A. Chakraborty, L. Staib, J. Duncan","doi":"10.1109/MMBIA.1996.534077","DOIUrl":"https://doi.org/10.1109/MMBIA.1996.534077","url":null,"abstract":"The wide availability of three-dimensional medical images has made their direct analysis a necessity. Accurately segmenting and quantifying structures is a key issue for such images. Conventional gradient-based surface finding however often suffers from a variety of limitations. This paper proposes a surface finding approach that uses in addition to gradient information, region information. This makes the resulting procedure more robust to noise and improper initialization. It uses Gauss's Divergence theorem to find the surface of of a homogeneous region-classified area in the image and integrates this with a gray level gradient-based surface finder. Experimental results show that indeed, as expected, a significant improvement is achieved as a consequence of the use of this extra information. Further these improvements are achieved with little increase in computational overhead, an advantage derived from the application of Gauss's Divergence theorem.","PeriodicalId":436387,"journal":{"name":"Proceedings of the Workshop on Mathematical Methods in Biomedical Image Analysis","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1996-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129521919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Deblurring the discrete Gaussian blur 去模糊离散高斯模糊
Pub Date : 1996-06-21 DOI: 10.1109/MMBIA.1996.534079
B. Mair, D.C. Wilson, Z. Réti
In 1995 Z. Reti presented a method for deblurring images blurred by the discrete Gaussian. The method is based on theorems borrowed from analytic number theory developed by Gauss, G. Jacobi (1829), and Ramanujan. One advantage of this method over similar ones developed for the continuous domain is that it provides exact formulas for the deblurring convolution. In addition, while deblurring the Gaussian in the continuous domain is an ill-posed inverse problem, deblurring the discrete Gaussian model results in a mathematically well-posed problem. The formulas presented here provide error bounds which relate the quality of the reconstructed image to that of the blurred image. This deblurring method is conveniently expressed in terms of multiplication by Toeplitz matrices whose diagonal entries decrease exponentially, thus rendering the method suitable for numerical approximations. Condition numbers are provided for various choices of /spl sigma/.
1995年,Z. Reti提出了一种消除离散高斯模糊图像的方法。该方法是基于从高斯、G.雅可比(1829)和拉马努金发展的解析数论中借用的定理。该方法相对于连续域的同类方法的一个优点是它提供了去模糊卷积的精确公式。此外,在连续域高斯模型的去模糊是一个不适定逆问题,而对离散高斯模型的去模糊则是一个数学上的适定问题。这里给出的公式提供了将重建图像的质量与模糊图像的质量联系起来的误差界限。这种去模糊方法被方便地表示为Toeplitz矩阵的乘法,该矩阵的对角线项呈指数减少,从而使该方法适合于数值近似。条件数提供了各种选择/spl σ /。
{"title":"Deblurring the discrete Gaussian blur","authors":"B. Mair, D.C. Wilson, Z. Réti","doi":"10.1109/MMBIA.1996.534079","DOIUrl":"https://doi.org/10.1109/MMBIA.1996.534079","url":null,"abstract":"In 1995 Z. Reti presented a method for deblurring images blurred by the discrete Gaussian. The method is based on theorems borrowed from analytic number theory developed by Gauss, G. Jacobi (1829), and Ramanujan. One advantage of this method over similar ones developed for the continuous domain is that it provides exact formulas for the deblurring convolution. In addition, while deblurring the Gaussian in the continuous domain is an ill-posed inverse problem, deblurring the discrete Gaussian model results in a mathematically well-posed problem. The formulas presented here provide error bounds which relate the quality of the reconstructed image to that of the blurred image. This deblurring method is conveniently expressed in terms of multiplication by Toeplitz matrices whose diagonal entries decrease exponentially, thus rendering the method suitable for numerical approximations. Condition numbers are provided for various choices of /spl sigma/.","PeriodicalId":436387,"journal":{"name":"Proceedings of the Workshop on Mathematical Methods in Biomedical Image Analysis","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1996-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125296313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Intensity ridge and widths for tubular object segmentation and description 用于管状物体分割和描述的强度脊和宽度
Pub Date : 1996-06-21 DOI: 10.1109/MMBIA.1996.534065
S. Aylward, E. Bullitt, S. Pizer, Dave H. Eberly
Introduces a technique for the automated description of tubular objects in 3D medical images. The goal of automated 3D object description is to extract a representation which consistently details the location, size, and structure of objects in 3D images using minimal user interaction. Such a representation provides a means by which objects can be classified, quantifiably evaluated, and registered. It also serves as a region of interest specification for visualization processes. The technique presented in this paper is suited for generating representations of 3D objects with nearly circular cross sections which have, possibly as a result of a global operation (e.g., blurring), intensity extrema near their centers. Such tubular objects commonly occur within human anatomy (e.g., vessels and selected bones). The medial axis of each of these objects is well approximated by its intensity ridge. The scales of the local maxima in medialness at all points along the ridge can be mapped to local width estimates. Together these measures capture the location, size, and structure of tubular objects. This paper covers the mathematical basis, the implementation issues, and the application of this technique to the extraction of vessels from 3D magnetic resonance angiographic images and bones from 3D X-ray computed tomographic images.
介绍了一种三维医学图像中管状物体的自动描述技术。自动化3D对象描述的目标是在使用最少的用户交互的情况下,提取出一种一致地详细描述3D图像中对象的位置、大小和结构的表示。这种表示提供了一种可以对对象进行分类、定量评估和注册的方法。它还可以作为可视化过程的兴趣区域规范。本文中提出的技术适用于生成具有近圆形横截面的3D物体的表示,这些物体可能由于全局操作(例如,模糊)而在其中心附近具有强度极值。这种管状物体通常出现在人体解剖学中(例如,血管和选定的骨骼)。每一个物体的中轴线都很好地近似于其强度脊。沿脊的所有点的局部最大中度的尺度可以映射到局部宽度估计值。这些措施一起捕捉到管状物体的位置、大小和结构。本文介绍了该技术的数学基础、实现问题,以及该技术在三维磁共振血管造影图像中血管提取和三维x射线计算机断层图像中骨骼提取中的应用。
{"title":"Intensity ridge and widths for tubular object segmentation and description","authors":"S. Aylward, E. Bullitt, S. Pizer, Dave H. Eberly","doi":"10.1109/MMBIA.1996.534065","DOIUrl":"https://doi.org/10.1109/MMBIA.1996.534065","url":null,"abstract":"Introduces a technique for the automated description of tubular objects in 3D medical images. The goal of automated 3D object description is to extract a representation which consistently details the location, size, and structure of objects in 3D images using minimal user interaction. Such a representation provides a means by which objects can be classified, quantifiably evaluated, and registered. It also serves as a region of interest specification for visualization processes. The technique presented in this paper is suited for generating representations of 3D objects with nearly circular cross sections which have, possibly as a result of a global operation (e.g., blurring), intensity extrema near their centers. Such tubular objects commonly occur within human anatomy (e.g., vessels and selected bones). The medial axis of each of these objects is well approximated by its intensity ridge. The scales of the local maxima in medialness at all points along the ridge can be mapped to local width estimates. Together these measures capture the location, size, and structure of tubular objects. This paper covers the mathematical basis, the implementation issues, and the application of this technique to the extraction of vessels from 3D magnetic resonance angiographic images and bones from 3D X-ray computed tomographic images.","PeriodicalId":436387,"journal":{"name":"Proceedings of the Workshop on Mathematical Methods in Biomedical Image Analysis","volume":"320 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1996-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116429135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 162
Automatic registration and alignment on a template of cardiac stress and rest SPECT images 在心脏压力和休息SPECT图像的模板上自动配准和对齐
Pub Date : 1996-06-21 DOI: 10.1109/MMBIA.1996.534073
J. Declerck, J. Feldmar, F. Betting, M. Goris
Single photon emission computed tomography (SPECT) imaging is used to assess the location or the extent of myocardial infarction or ischemia. A method is proposed to decrease the effect of operator variability and morphologically blind sampling in the quantification of scintigraphic myocardial perfusion studies. To effect this, the patient's myocardial images (target cases) are registered automatically over a template image, utilizing non-rigid transformations. The registration method is an adaptation of the Iterative Closest Point algorithm. Experiments have been conducted on a database including 40 pairs of images selected to obtain a group of image abnormalities and variability. Upon the successful clinical validation of this work, a reliable, operator independent method for the analysis and interpretation of myocardial perfusion scintigraphies will be available.
单光子发射计算机断层扫描(SPECT)成像用于评估心肌梗死或缺血的位置或程度。提出了一种方法,以减少操作员的可变性和形态学盲采样的影响,在定量的闪烁心肌灌注研究。为了实现这一点,患者的心肌图像(目标病例)在模板图像上自动注册,利用非刚性转换。该配准方法是对迭代最近点算法的改进。在数据库中选取了40对图像进行实验,得到了一组图像的异常和变异性。在这项工作的成功临床验证后,一种可靠的、独立于操作人员的心肌灌注闪烁图分析和解释方法将可用。
{"title":"Automatic registration and alignment on a template of cardiac stress and rest SPECT images","authors":"J. Declerck, J. Feldmar, F. Betting, M. Goris","doi":"10.1109/MMBIA.1996.534073","DOIUrl":"https://doi.org/10.1109/MMBIA.1996.534073","url":null,"abstract":"Single photon emission computed tomography (SPECT) imaging is used to assess the location or the extent of myocardial infarction or ischemia. A method is proposed to decrease the effect of operator variability and morphologically blind sampling in the quantification of scintigraphic myocardial perfusion studies. To effect this, the patient's myocardial images (target cases) are registered automatically over a template image, utilizing non-rigid transformations. The registration method is an adaptation of the Iterative Closest Point algorithm. Experiments have been conducted on a database including 40 pairs of images selected to obtain a group of image abnormalities and variability. Upon the successful clinical validation of this work, a reliable, operator independent method for the analysis and interpretation of myocardial perfusion scintigraphies will be available.","PeriodicalId":436387,"journal":{"name":"Proceedings of the Workshop on Mathematical Methods in Biomedical Image Analysis","volume":"44 11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1996-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125678908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 47
Extension of the ICP algorithm to non-rigid intensity-based registration of 3D volumes 将ICP算法扩展到基于非刚性强度的三维体配准
Pub Date : 1996-06-21 DOI: 10.1109/MMBIA.1996.534060
J. Feldmar, G. Malandain, J. Declerck, N. Ayache
Presents a new registration and gain correction algorithm for 3D medical images. It is intensity based. The basic idea is to represent the images by 4D points (x/sub j/, y/sub j/, z/sub j/, i/sub j/) and to define a global energy function based on this representation. For minimization, the authors propose a technique which does not require to compute the derivatives of this criterion with respect to the parameters. It can be understood as an extension of the Iterative Closest Point algorithm (P. Besl and N. McKay, 1992; Z. Zhang, 1992) or as an application of the formalism proposed by L. Cohen (Use of auxiliary variables in computer vision problems. In Proceedings of the Fifth International Conference on Computer Vision (ICCV '95), Boston, June 1995). Two parameters allow one to have a coarse to fine strategy both for resolution and deformation. The authors' technique presents the advantage to minimize a well defined global criterion to deal with various classes of transformations (for example rigid, affine and volume spline), to be simple to implement and to be efficient in practice. Results on real brain and heart 3D images are presented to demonstrate the validity of the authors' approach.
提出了一种新的三维医学图像配准与增益校正算法。这是基于强度的。基本思想是用4D点(x/sub j/, y/sub j/, z/sub j/, i/sub j/)表示图像,并根据这种表示定义一个全局能量函数。为了最小化,作者提出了一种不需要计算该准则相对于参数的导数的技术。它可以理解为迭代最近点算法的扩展(P. Besl和N. McKay, 1992;Z. Zhang, 1992)或作为L. Cohen提出的形式主义的应用(计算机视觉问题中辅助变量的使用)。第五届计算机视觉国际会议论文集(ICCV '95),波士顿,1995年6月)。两个参数允许一个有一个粗到细的策略,无论是分辨率和变形。作者的技术的优势在于最小化一个定义良好的全局准则来处理各种类型的变换(例如刚性、仿射和体积样条),实现简单,在实践中效率高。在真实的大脑和心脏三维图像上的结果证明了作者方法的有效性。
{"title":"Extension of the ICP algorithm to non-rigid intensity-based registration of 3D volumes","authors":"J. Feldmar, G. Malandain, J. Declerck, N. Ayache","doi":"10.1109/MMBIA.1996.534060","DOIUrl":"https://doi.org/10.1109/MMBIA.1996.534060","url":null,"abstract":"Presents a new registration and gain correction algorithm for 3D medical images. It is intensity based. The basic idea is to represent the images by 4D points (x/sub j/, y/sub j/, z/sub j/, i/sub j/) and to define a global energy function based on this representation. For minimization, the authors propose a technique which does not require to compute the derivatives of this criterion with respect to the parameters. It can be understood as an extension of the Iterative Closest Point algorithm (P. Besl and N. McKay, 1992; Z. Zhang, 1992) or as an application of the formalism proposed by L. Cohen (Use of auxiliary variables in computer vision problems. In Proceedings of the Fifth International Conference on Computer Vision (ICCV '95), Boston, June 1995). Two parameters allow one to have a coarse to fine strategy both for resolution and deformation. The authors' technique presents the advantage to minimize a well defined global criterion to deal with various classes of transformations (for example rigid, affine and volume spline), to be simple to implement and to be efficient in practice. Results on real brain and heart 3D images are presented to demonstrate the validity of the authors' approach.","PeriodicalId":436387,"journal":{"name":"Proceedings of the Workshop on Mathematical Methods in Biomedical Image Analysis","volume":"75 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1996-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122175953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 52
Synthesis of an individualized cranial atlas with dysmorphic shape 个体化畸形颅骨图谱的合成
Pub Date : 1996-06-21 DOI: 10.1109/MMBIA.1996.534083
G. Christensen, A. Kane, J. Marsh, M. Vannier
A new method for non-rigid registration of a normal infant CT head atlas with CT data of infants with abnormal skull shape is presented. An individualized atlas is synthesized by computing a volume transformation from the normal atlas to the target data set shape. This process begins rigidly by eliminating translation and rotation differences and proceeds non-rigidly to eliminate anatomical shape differences. Operator specified anatomical landmarks are used to find the initial rigid transformation. Non-rigid registration is achieved by constraining the transformation by the low frequency modes of vibration of a 3D linear-elastic solid while minimizing the squared intensity difference between atlas and target CT image volumes. Results are presented in which the CT atlas was transformed into the shape of several infants with various types of craniofacial deformities.
提出了一种将正常婴儿CT头颅图谱与畸形婴儿CT数据进行非刚性配准的新方法。通过计算从正常地图集到目标数据集形状的体变换,合成个性化地图集。这个过程从消除平移和旋转差异开始,然后进行非刚性消除解剖形状差异。使用算子指定的解剖标志来求初始刚性变换。非刚性配准是通过限制三维线弹性实体的低频振动模式的变换来实现的,同时最小化图谱和目标CT图像体积之间的强度差的平方。结果提出了CT图谱转化为形状的几个婴儿不同类型的颅面畸形。
{"title":"Synthesis of an individualized cranial atlas with dysmorphic shape","authors":"G. Christensen, A. Kane, J. Marsh, M. Vannier","doi":"10.1109/MMBIA.1996.534083","DOIUrl":"https://doi.org/10.1109/MMBIA.1996.534083","url":null,"abstract":"A new method for non-rigid registration of a normal infant CT head atlas with CT data of infants with abnormal skull shape is presented. An individualized atlas is synthesized by computing a volume transformation from the normal atlas to the target data set shape. This process begins rigidly by eliminating translation and rotation differences and proceeds non-rigidly to eliminate anatomical shape differences. Operator specified anatomical landmarks are used to find the initial rigid transformation. Non-rigid registration is achieved by constraining the transformation by the low frequency modes of vibration of a 3D linear-elastic solid while minimizing the squared intensity difference between atlas and target CT image volumes. Results are presented in which the CT atlas was transformed into the shape of several infants with various types of craniofacial deformities.","PeriodicalId":436387,"journal":{"name":"Proceedings of the Workshop on Mathematical Methods in Biomedical Image Analysis","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1996-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131947316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 22
Non-invasive functional brain mapping using registered transcranial magnetic stimulation 使用经颅磁刺激进行非侵入性脑功能测绘
Pub Date : 1996-06-21 DOI: 10.1109/MMBIA.1996.534055
G. Ettinger, W. Grimson, M. Leventon, Ron Kikinis, V. Gugino, W. Cote, M. Karapelou, L. Aglio, M. Shenton, G. Potts, Eben Alexander
The authors describe a method for mapping the functional regions of the brain using a transcranial magnetic stimulation (TMS) device. This device, when placed on a subject's scalp, stimulates the underlying neurons by generating focused magnetic field pulses. A brain mapping is then generated by measuring responses of different motor and sensory functions to this stimulation. The key process in generating this mapping is the association of the 3D positions and orientations of the TMS probe on the scalp to a 3D brain reconstruction such as is feasible with a magnetic resonance image (MRI). The authors perform this matching process by (1) registering the subject's head position to an a priori MRI scan, (2) tracking the 3D position/orientation of the TMS probe, (3) transforming the TMS probe position/orientation to the MRI coordinate frame, and (4) tracking movements in the subject's head position to factor out any head motion. The resultant process generates a high resolution, accurate brain mapping which supports surgical planning, surgical guidance, neuroanatomy research, and psychiatric therapy. When compared to other functional imaging modalities, this approach exhibits much lower cost, greater portability, and more direct active control over the functional areas being studied.
作者描述了一种使用经颅磁刺激(TMS)装置绘制大脑功能区域的方法。当这个装置被放置在受试者的头皮上时,它会通过产生聚焦的磁场脉冲来刺激底层的神经元。然后,通过测量不同运动和感觉功能对这种刺激的反应,生成大脑图谱。生成这种映射的关键过程是将头皮上TMS探针的3D位置和方向与三维大脑重建(如磁共振成像)相关联。作者通过(1)将受试者的头部位置注册到先验的MRI扫描中,(2)跟踪TMS探针的3D位置/方向,(3)将TMS探针的位置/方向转换为MRI坐标框架,以及(4)跟踪受试者头部位置的运动以剔除任何头部运动。由此产生的过程产生高分辨率,准确的大脑图谱,支持手术计划,手术指导,神经解剖学研究和精神治疗。与其他功能成像方式相比,该方法成本更低,便携性更强,对所研究的功能区域进行更直接的主动控制。
{"title":"Non-invasive functional brain mapping using registered transcranial magnetic stimulation","authors":"G. Ettinger, W. Grimson, M. Leventon, Ron Kikinis, V. Gugino, W. Cote, M. Karapelou, L. Aglio, M. Shenton, G. Potts, Eben Alexander","doi":"10.1109/MMBIA.1996.534055","DOIUrl":"https://doi.org/10.1109/MMBIA.1996.534055","url":null,"abstract":"The authors describe a method for mapping the functional regions of the brain using a transcranial magnetic stimulation (TMS) device. This device, when placed on a subject's scalp, stimulates the underlying neurons by generating focused magnetic field pulses. A brain mapping is then generated by measuring responses of different motor and sensory functions to this stimulation. The key process in generating this mapping is the association of the 3D positions and orientations of the TMS probe on the scalp to a 3D brain reconstruction such as is feasible with a magnetic resonance image (MRI). The authors perform this matching process by (1) registering the subject's head position to an a priori MRI scan, (2) tracking the 3D position/orientation of the TMS probe, (3) transforming the TMS probe position/orientation to the MRI coordinate frame, and (4) tracking movements in the subject's head position to factor out any head motion. The resultant process generates a high resolution, accurate brain mapping which supports surgical planning, surgical guidance, neuroanatomy research, and psychiatric therapy. When compared to other functional imaging modalities, this approach exhibits much lower cost, greater portability, and more direct active control over the functional areas being studied.","PeriodicalId":436387,"journal":{"name":"Proceedings of the Workshop on Mathematical Methods in Biomedical Image Analysis","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1996-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125386362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 15
Tracking 3-D pulmonary tree structures 跟踪三维肺树结构
Pub Date : 1996-06-21 DOI: 10.1109/MMBIA.1996.534068
C. Pisupati, L. Wolff, W. Mitzner, E. Zerhouni
Physiological measurements like branch angles, branch lengths, branch diameters and branch cross-sectional area of the 3-D pulmonary tree structures are clinically essential in evaluating the function of normal and diseased lung and during the breathing process. In order to facilitate these measurements and study relative structural changes, the 3-D lung tree volumes are reduced to a 3-D Euclidean straight line central axis tree. The central axis tree captures the branch topology and geometric features of the tree volume. Since matching 3-D tree volumes is complex, as they change in branch topology and geometry, the authors accomplish it by designing an efficient algorithm that matches their corresponding central axis trees. The algorithm takes two binary central axis trees T/sub 1/=(V/sub 1/,E/sub 1/,W/sub 1/) and T/sub 2/=(V/sub 2/,E/sub 2/,W/sub 2/), where W/sub 1/ and W/sub 2/ are set of tuples containing geometric attributes corresponding to the nodes in T/sub 1/ and T/sub 2/, as inputs and returns the one-to-one matching function f of nodes in T/sub 1/ to T/sub 2/ that preserves the tree topology and closely matches the geometric attributes of these trees, i.e. branch points, branch lengths, and branch angles between mapped nodes of T/sub 1/ and T/sub 2/. Since the topology match alone could result in many choices of the mapping function f, the authors prune these choices by incorporating constraints on the geometric attributes of nodes in T/sub 1/ and T/sub 2/. The authors design a linear time algorithm that matches the branch topology and geometric features of T/sub 1/ and T/sub 2/. The authors' algorithm produced accurate matchings on various airway data sets of a dog lung obtained from Computed Tomography under simulated breathing conditions. T/sub 1/ and T/sub 2/ are obtained by running a two-pass central axis algorithm on the tree volumes.
肺三维树状结构的分支角度、分支长度、分支直径、分支截面积等生理测量在临床评价正常和病变肺的功能以及呼吸过程中是必不可少的。为了便于这些测量和研究相对的结构变化,将三维肺树体积简化为三维欧几里得直线中心轴树。中轴树捕获了树体的分支拓扑和几何特征。由于匹配三维树体是复杂的,因为它们在分支拓扑和几何上的变化,作者通过设计一个有效的算法来匹配相应的中心轴树来完成它。该算法以两棵二叉中轴树T/sub 1/=(V/sub 1/,E/sub 1/,W/sub 1/)和T/sub 2/=(V/sub 2/,E/sub 2/,W/sub 2/)为输入,其中W/sub 1/和W/sub 2/是包含T/sub 1/和T/sub 2/中节点对应的几何属性的元组集合,并返回T/sub 1/中节点到T/sub 2/的一对一匹配函数f,该函数保持了树的拓扑结构,并与这些树的几何属性紧密匹配,即分支点、分支长度、映射节点间的分支角为T/sub 1/和T/sub 2/。由于拓扑匹配本身可能导致映射函数f的许多选择,因此作者通过结合对T/sub 1/和T/sub 2/中节点的几何属性的约束来减少这些选择。设计了一种匹配T/sub 1/和T/sub 2/分支拓扑和几何特征的线性时间算法。作者的算法对模拟呼吸条件下从计算机断层扫描中获得的狗肺的各种气道数据集进行了精确匹配。T/sub 1/和T/sub 2/是通过在树体上运行两遍中心轴算法得到的。
{"title":"Tracking 3-D pulmonary tree structures","authors":"C. Pisupati, L. Wolff, W. Mitzner, E. Zerhouni","doi":"10.1109/MMBIA.1996.534068","DOIUrl":"https://doi.org/10.1109/MMBIA.1996.534068","url":null,"abstract":"Physiological measurements like branch angles, branch lengths, branch diameters and branch cross-sectional area of the 3-D pulmonary tree structures are clinically essential in evaluating the function of normal and diseased lung and during the breathing process. In order to facilitate these measurements and study relative structural changes, the 3-D lung tree volumes are reduced to a 3-D Euclidean straight line central axis tree. The central axis tree captures the branch topology and geometric features of the tree volume. Since matching 3-D tree volumes is complex, as they change in branch topology and geometry, the authors accomplish it by designing an efficient algorithm that matches their corresponding central axis trees. The algorithm takes two binary central axis trees T/sub 1/=(V/sub 1/,E/sub 1/,W/sub 1/) and T/sub 2/=(V/sub 2/,E/sub 2/,W/sub 2/), where W/sub 1/ and W/sub 2/ are set of tuples containing geometric attributes corresponding to the nodes in T/sub 1/ and T/sub 2/, as inputs and returns the one-to-one matching function f of nodes in T/sub 1/ to T/sub 2/ that preserves the tree topology and closely matches the geometric attributes of these trees, i.e. branch points, branch lengths, and branch angles between mapped nodes of T/sub 1/ and T/sub 2/. Since the topology match alone could result in many choices of the mapping function f, the authors prune these choices by incorporating constraints on the geometric attributes of nodes in T/sub 1/ and T/sub 2/. The authors design a linear time algorithm that matches the branch topology and geometric features of T/sub 1/ and T/sub 2/. The authors' algorithm produced accurate matchings on various airway data sets of a dog lung obtained from Computed Tomography under simulated breathing conditions. T/sub 1/ and T/sub 2/ are obtained by running a two-pass central axis algorithm on the tree volumes.","PeriodicalId":436387,"journal":{"name":"Proceedings of the Workshop on Mathematical Methods in Biomedical Image Analysis","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1996-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116204690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 16
期刊
Proceedings of the Workshop on Mathematical Methods in Biomedical Image Analysis
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1