The devastating impact of COVID-19 pandemic, its fast-tracked vaccines and authorized treatments have led to more volunteers signing up to be part of clinical studies than any time in recent history. We sought to investigate the relationship between increased knowledge of vaccine clinical trials and willingness to participate in future vaccine trials. A convenience sample survey of the United States residents was conducted in May 2021. Over 1,100 adults completed questions about their knowledge of clinical vaccine trials and attitudes toward participation in future trials. A total of 1149 respondents completed the survey. The median age was 29. Amongst respondents, 47.9% were women. Over 85% had attended college. Most were married (60.1%). A significant proportion of respondents were of Hispanic origin (42.2%). Higher Knowledge Scores were observed for female respondents (p <0.001);>30 years-old respondents (p <0.001) and respondents with a bachelors’ degree or higher (p <0.05). Overall, the survey respondents felt that their COVID-19 pandemic experience had increased their knowledge of vaccine trials (807, 70.2%) and willingness to participate in future vaccine studies (677, 58.9%). In addition, over half of the respondents expressed willingness to sign up for a future vaccine study of any kind (51.5%) with another 38.0% willing to consider it. The findings from this survey confirms significant increased interest in clinical vaccine study participation in the midst of COVID-19 pandemic and provides actionable insights to improve outreach efforts with underrepresented populations in clinical research. Keywords: COVID-19; Clinical Trials Participat
{"title":"Greater Awareness and Knowledge of Clinical Research Increases Willingness to Participate in Future Vaccine TrialsAn Examination of the Enduring Impact of COVID-19 Pandemic","authors":"Faye O'Brien","doi":"10.54026/cjct/1005","DOIUrl":"https://doi.org/10.54026/cjct/1005","url":null,"abstract":"The devastating impact of COVID-19 pandemic, its fast-tracked vaccines and authorized treatments have led to more volunteers signing up to be part of clinical studies than any time in recent history. We sought to investigate the relationship between increased knowledge of vaccine clinical trials and willingness to participate in future vaccine trials. A convenience sample survey of the United States residents was conducted in May 2021. Over 1,100 adults completed questions about their knowledge of clinical vaccine trials and attitudes toward participation in future trials. A total of 1149 respondents completed the survey. The median age was 29. Amongst respondents, 47.9% were women. Over 85% had attended college. Most were married (60.1%). A significant proportion of respondents were of Hispanic origin (42.2%). Higher Knowledge Scores were observed for female respondents (p <0.001);>30 years-old respondents (p <0.001) and respondents with a bachelors’ degree or higher (p <0.05). Overall, the survey respondents felt that their COVID-19 pandemic experience had increased their knowledge of vaccine trials (807, 70.2%) and willingness to participate in future vaccine studies (677, 58.9%). In addition, over half of the respondents expressed willingness to sign up for a future vaccine study of any kind (51.5%) with another 38.0% willing to consider it. The findings from this survey confirms significant increased interest in clinical vaccine study participation in the midst of COVID-19 pandemic and provides actionable insights to improve outreach efforts with underrepresented populations in clinical research. Keywords: COVID-19; Clinical Trials Participat","PeriodicalId":436742,"journal":{"name":"Corpus Journal of Clinical Trails (CJCT)","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128980497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Coronary Obstructive Pulmonary Disease (COPD) is a reversible incomplete form of advanced airflow obstruction and abnormal inflammation of lung tissues occurred during the progression of this disease. The primary symptoms of this disease involves wheezing phenomena that remain persistent, recurrent chest infectious problems, rest breathlessness that prolongs with exercise, mucus hyper secretion, consistent coughing with phlegm and ultimately destruction of parenchyma cells of lungs due to severe coughing. In this report, we are discussing the case study of COPD pneumonia patient due to vulnerability of this particular disease.
{"title":"A Prospective Clinical Case Study of COPD (Coronary Obstructive Pulmonary Disease) Patient Shifted to Emergency","authors":"Rehman Zafar","doi":"10.54026/cjct/1004","DOIUrl":"https://doi.org/10.54026/cjct/1004","url":null,"abstract":"Coronary Obstructive Pulmonary Disease (COPD) is a reversible incomplete form of advanced airflow obstruction and abnormal inflammation of lung tissues occurred during the progression of this disease. The primary symptoms of this disease involves wheezing phenomena that remain persistent, recurrent chest infectious problems, rest breathlessness that prolongs with exercise, mucus hyper secretion, consistent coughing with phlegm and ultimately destruction of parenchyma cells of lungs due to severe coughing. In this report, we are discussing the case study of COPD pneumonia patient due to vulnerability of this particular disease.","PeriodicalId":436742,"journal":{"name":"Corpus Journal of Clinical Trails (CJCT)","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129307075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A large part of the world population is affected by some temporomandibular joint disorder (TMD). The challenges in the treatment of these disorders start from its proper diagnosis, which is often done inappropriately, to the choice of therapy. The highest prevalence is in cases of temporomandibular disorder of muscular origin. The symptoms resulting from TMD are usually accentuated in periods of greater emotional stress. With the Sars-CoV-2 (Covid-19) pandemic, many patients lost family members, jobs and their own income, and neurological disorders, linked to anxiety and sleep disorders, increased the occurrence of symptoms connected to TMD. Conservative treatment should be the first choice to combat TMD, when all these alternatives are exhausted, surgical treatment can be planned, according to the patient’s pathology. Generally, the treatment of choice is the use of drugs, but a large number of alternatives have emerged and some have shown to be very promising. This review seeks to talk a little about drug treatment for the relief of TMD symptoms.
{"title":"Drug Treatment in Temporomandibular Disorder","authors":"Igor Figueiredo Pereira","doi":"10.54026/cjct/1003","DOIUrl":"https://doi.org/10.54026/cjct/1003","url":null,"abstract":"A large part of the world population is affected by some temporomandibular joint disorder (TMD). The challenges in the treatment of these disorders start from its proper diagnosis, which is often done inappropriately, to the choice of therapy. The highest prevalence is in cases of temporomandibular disorder of muscular origin. The symptoms resulting from TMD are usually accentuated in periods of greater emotional stress. With the Sars-CoV-2 (Covid-19) pandemic, many patients lost family members, jobs and their own income, and neurological disorders, linked to anxiety and sleep disorders, increased the occurrence of symptoms connected to TMD. Conservative treatment should be the first choice to combat TMD, when all these alternatives are exhausted, surgical treatment can be planned, according to the patient’s pathology. Generally, the treatment of choice is the use of drugs, but a large number of alternatives have emerged and some have shown to be very promising. This review seeks to talk a little about drug treatment for the relief of TMD symptoms.","PeriodicalId":436742,"journal":{"name":"Corpus Journal of Clinical Trails (CJCT)","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115459560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bulimia nervosa is an eating disorder that, like anorexia nervosa, is of psychological origin and can have horrible physical consequences. While anorexics simply starve themselves, bulimics “cleanse” themselves of vomiting they have caused themselves or other forms of dealing with extra calories. Bulimics also often use weight loss pills, laxatives and diuretics to lose weight, but also use extensive exercise or fasting. Unlike anorexic people, they are usually of normal build, sometimes even bigger, while in combination with anorexia they are extremely thin. Cleansing can have two purposes: preventing weight gain, and temporarily relieving depression and other negative feelings.
{"title":"A Few Words about Bulimia Nervosa","authors":"Siniša Franjić","doi":"10.54026/cjct/1002","DOIUrl":"https://doi.org/10.54026/cjct/1002","url":null,"abstract":"Bulimia nervosa is an eating disorder that, like anorexia nervosa, is of psychological origin and can have horrible physical consequences. While anorexics simply starve themselves, bulimics “cleanse” themselves of vomiting they have caused themselves or other forms of dealing with extra calories. Bulimics also often use weight loss pills, laxatives and diuretics to lose weight, but also use extensive exercise or fasting. Unlike anorexic people, they are usually of normal build, sometimes even bigger, while in combination with anorexia they are extremely thin. Cleansing can have two purposes: preventing weight gain, and temporarily relieving depression and other negative feelings.","PeriodicalId":436742,"journal":{"name":"Corpus Journal of Clinical Trails (CJCT)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131847325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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