The paper describes the professional activities and merits of Margarita A. Barskaya, a pediatric surgeon, in celebration of her anniversary.
本文介绍了小儿外科医生玛格丽塔-巴尔斯卡娅（Margarita A. Barskaya）的职业活动和功绩，以庆祝她的诞辰。
{"title":"To the anniversary of Margarita A. Barskaya","authors":"Oleg S. Gorbachev","doi":"10.17816/psaic1790","DOIUrl":"https://doi.org/10.17816/psaic1790","url":null,"abstract":"The paper describes the professional activities and merits of Margarita A. Barskaya, a pediatric surgeon, in celebration of her anniversary.","PeriodicalId":437552,"journal":{"name":"Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care","volume":"23 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140714118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. A. Borisov, I. I. Gordienko, N. Tsap, G. Baigonakova, E. Marchenko, V. A. Larikov
BACKGROUND: The relevance of this study was supported by the increasing number of infectious complications of bone augmentation in children and adults. Currently, porous titanium nickelide alloys are among the most preferred materials used in bone plasty. Despite the observable advantages of porous nickelide titanium alloys in terms of biochemical and biomechanical compatibility with the body, research on the antibacterial activity of alloys is ongoing to counter the development of infections at the implant–biological tissue border. AIM: To perform an experimental study of the biocompatible antibacterial surface in porous titanium nickelide alloys with the addition of silver nanoparticles. MATERIALS AND METHODS: Titanium nickelide alloys with 62% porosity were obtained using the self-propagating high-temperature synthesis method from nickel, titanium, and nanosilver powders at concentrations of 0.2 at.% Ag, 0.5 at.% Ag, and 1.0 at.% Ag, respectively. The experiment was conducted on nine sexually mature female white laboratory rats. They were divided into three groups, with three rats each. All animals were implanted with titanium nickelide along with porous granules of silver additives. The first group was the control, the second received 0.2 at.% silver, and the third received 0.5% silver. The standard method of incubating Staphylococcus epidermidis in liquid broth in the presence of the studied images was used to determine bactericidal activity, followed by seeding on solid media and counting colonies. RESULTS: The antibacterial effect of the samples on S. epidermidis gradually increased with increasing silver concentration. The significance of the differences between the experiment and control was confirmed by Student’s criterion p 0.005, whereas the sample without silver nanoparticles and the control do not differ significantly. Thus, these alloys may have bioactive properties because they contain silver nanoparticles. An alloy with a silver concentration of 0.5 at.% Ag showed the best antibacterial activity to S. epidermidis. In the clinical evaluation of the results of the experimental study, purulent inflammatory complications were not observed in all animals at all times. On day 75, the animals underwent computed tomography, which showed good occupancy of the bone defect and absence of a dystrophic effect on the area where the bone and soft tissue are in contact with the material. CONCLUSIONS: If the concentration of silver nanoparticles is increased up to 0.5 at%, the antibacterial activity and cytocompatibility of the implant also increase. Clinical experimental evaluation in all groups of animals showed that osteointegration of alloys with 0.5 at.% Ag begins immediately after implantation and is completed 2 weeks earlier than that in the remaining groups.
背景：儿童和成人骨增量术后感染性并发症的数量不断增加，这支持了本研究的相关性。目前，多孔镍化钛合金是骨成形术中最常用的材料之一。尽管多孔镍化钛合金在与人体的生物化学和生物力学相容性方面具有明显的优势，但目前仍在对合金的抗菌活性进行研究，以防止在植入物与生物组织交界处发生感染。目的：对添加了纳米银颗粒的多孔镍化钛合金的生物相容性抗菌表面进行实验研究。材料与方法：采用自蔓延高温合成法，从镍粉、钛粉和纳米银粉中分别以 0.2 at.% Ag、0.5 at.% Ag 和 1.0 at.% Ag 的浓度获得孔隙率为 62% 的钛镍合金。实验以九只性成熟的雌性白色实验鼠为对象。它们被分为三组，每组三只。所有动物都植入了镍化钛和多孔银添加剂颗粒。第一组为对照组，第二组接受 0.2%的银，第三组接受 0.5%的银。测定杀菌活性的标准方法是将表皮葡萄球菌放在有所研究图像存在的液体肉汤中培养，然后在固体培养基上播种并计数菌落。结果：随着银浓度的增加，样品对表皮葡萄球菌的抗菌效果逐渐增强。实验与对照之间的差异经学生标准 p 0.005 检验，差异显著，而不含纳米银的样品与对照差异不显著。因此，这些合金可能因为含有纳米银粒子而具有生物活性特性。银浓度为 0.5%的合金对表皮葡萄球菌的抗菌活性最好。在对实验研究结果进行临床评估时，并非所有动物在任何时候都能观察到化脓性炎症并发症。第 75 天，对动物进行了计算机断层扫描，结果显示骨缺损的占位情况良好，骨和软组织与材料接触的区域没有萎缩效应。结论：如果将纳米银粒子的浓度提高到 0.5%，植入物的抗菌活性和细胞相容性也会提高。各组动物的临床实验评估结果表明，含 0.5%银的合金在植入后立即开始骨整合，并比其他组的动物提前两周完成骨整合。
{"title":"Antibacterial activity and biocompatibility of titanium nickelide augments with the addition of silver nanoparticles for bone grafting: an experimental study","authors":"S. A. Borisov, I. I. Gordienko, N. Tsap, G. Baigonakova, E. Marchenko, V. A. Larikov","doi":"10.17816/psaic1566","DOIUrl":"https://doi.org/10.17816/psaic1566","url":null,"abstract":"BACKGROUND: The relevance of this study was supported by the increasing number of infectious complications of bone augmentation in children and adults. Currently, porous titanium nickelide alloys are among the most preferred materials used in bone plasty. Despite the observable advantages of porous nickelide titanium alloys in terms of biochemical and biomechanical compatibility with the body, research on the antibacterial activity of alloys is ongoing to counter the development of infections at the implant–biological tissue border. \u0000AIM: To perform an experimental study of the biocompatible antibacterial surface in porous titanium nickelide alloys with the addition of silver nanoparticles. \u0000MATERIALS AND METHODS: Titanium nickelide alloys with 62% porosity were obtained using the self-propagating high-temperature synthesis method from nickel, titanium, and nanosilver powders at concentrations of 0.2 at.% Ag, 0.5 at.% Ag, and 1.0 at.% Ag, respectively. The experiment was conducted on nine sexually mature female white laboratory rats. They were divided into three groups, with three rats each. All animals were implanted with titanium nickelide along with porous granules of silver additives. The first group was the control, the second received 0.2 at.% silver, and the third received 0.5% silver. The standard method of incubating Staphylococcus epidermidis in liquid broth in the presence of the studied images was used to determine bactericidal activity, followed by seeding on solid media and counting colonies. \u0000RESULTS: The antibacterial effect of the samples on S. epidermidis gradually increased with increasing silver concentration. The significance of the differences between the experiment and control was confirmed by Student’s criterion p 0.005, whereas the sample without silver nanoparticles and the control do not differ significantly. Thus, these alloys may have bioactive properties because they contain silver nanoparticles. An alloy with a silver concentration of 0.5 at.% Ag showed the best antibacterial activity to S. epidermidis. In the clinical evaluation of the results of the experimental study, purulent inflammatory complications were not observed in all animals at all times. On day 75, the animals underwent computed tomography, which showed good occupancy of the bone defect and absence of a dystrophic effect on the area where the bone and soft tissue are in contact with the material. \u0000CONCLUSIONS: If the concentration of silver nanoparticles is increased up to 0.5 at%, the antibacterial activity and cytocompatibility of the implant also increase. Clinical experimental evaluation in all groups of animals showed that osteointegration of alloys with 0.5 at.% Ag begins immediately after implantation and is completed 2 weeks earlier than that in the remaining groups.","PeriodicalId":437552,"journal":{"name":"Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care","volume":"17 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140715970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BACKGROUND: Diffuse purulent peritonitis is the most severe complication of abdominal surgical pathology accompanied by the development of serious metabolic disorders, and its elimination is a preoperative task. AIM: This study aimed to compare traditional preoperative preparations using a new scheme that provides a differential approach considering the stage of peritonitis, degree of endotoxicosis, child’s age, and succinate administration. MATERIALS AND METHODS: An analysis of the results of treatment of patients aged 1–14 years (average age 7.9 ± 3.9 years) with diffuse purulent peritonitis of various etiologies who were treated from 2006 to 2022 in the children’s surgical department of the V.D. Seredavin Samara Regional Hospital, Samara. The patients were divided into two groups. The main group included 237 patients who underwent preoperative preparation according to the proposed scheme (depending on age, peritonitis stage, and degree of endotoxemia) lasting at least 4–6 h. In addition, for intracorporeal detoxification, the antihypoxant meglumine sodium succinate was used. The control group comprised 102 children who received traditional therapy according to generally accepted approaches and national guidelines for pediatric surgery lasting 2–3 h. Changes in hemodynamic parameters, electrolytes, hematocrit, platelets, and blood gases were comprehensively examined. RESULTS: After preoperative preparation, a statistically significant improvement in hemodynamic parameters was observed in the main group compared with that in the control group; the indicators were close to normal values. The dynamics of hematological parameters indicated more pronounced hemodilution in patients of the main group of all ages, which proves a significant improvement in the rheological properties of blood. Electrolyte and blood gas indicators did not reach the indicators of healthy children in any groups; however, in the main group, they were closer to normal. Complications of varying severity in the main group occurred in 21 children (8.8% ± 1.4%; p 0.001), whereas in the control group, they were diagnosed in 47 patients (46.0% ± 4.6%). A statistically significant reduction in the length of stay of patients in the intensive care unit after surgery was noted in 80% of children in the main group. CONCLUSIONS: The proposed scheme of preoperative preparation based on a differential approach using the antihypoxant meglumine sodium demonstrated greater effectiveness than traditional treatment. The composition, volume, and duration of preoperative preparation are dependent on the state of homeostasis and the age of the patient.
{"title":"Differential approach to preoperative preparations for diffuse purulent peritonitis in children","authors":"V. A. Zavyalkin, M. A. Barskaya, S. Yukhimets","doi":"10.17816/psaic1570","DOIUrl":"https://doi.org/10.17816/psaic1570","url":null,"abstract":"BACKGROUND: Diffuse purulent peritonitis is the most severe complication of abdominal surgical pathology accompanied by the development of serious metabolic disorders, and its elimination is a preoperative task. \u0000AIM: This study aimed to compare traditional preoperative preparations using a new scheme that provides a differential approach considering the stage of peritonitis, degree of endotoxicosis, child’s age, and succinate administration. \u0000MATERIALS AND METHODS: An analysis of the results of treatment of patients aged 1–14 years (average age 7.9 ± 3.9 years) with diffuse purulent peritonitis of various etiologies who were treated from 2006 to 2022 in the children’s surgical department of the V.D. Seredavin Samara Regional Hospital, Samara. The patients were divided into two groups. The main group included 237 patients who underwent preoperative preparation according to the proposed scheme (depending on age, peritonitis stage, and degree of endotoxemia) lasting at least 4–6 h. In addition, for intracorporeal detoxification, the antihypoxant meglumine sodium succinate was used. The control group comprised 102 children who received traditional therapy according to generally accepted approaches and national guidelines for pediatric surgery lasting 2–3 h. Changes in hemodynamic parameters, electrolytes, hematocrit, platelets, and blood gases were comprehensively examined. \u0000RESULTS: After preoperative preparation, a statistically significant improvement in hemodynamic parameters was observed in the main group compared with that in the control group; the indicators were close to normal values. The dynamics of hematological parameters indicated more pronounced hemodilution in patients of the main group of all ages, which proves a significant improvement in the rheological properties of blood. Electrolyte and blood gas indicators did not reach the indicators of healthy children in any groups; however, in the main group, they were closer to normal. Complications of varying severity in the main group occurred in 21 children (8.8% ± 1.4%; p 0.001), whereas in the control group, they were diagnosed in 47 patients (46.0% ± 4.6%). A statistically significant reduction in the length of stay of patients in the intensive care unit after surgery was noted in 80% of children in the main group. \u0000CONCLUSIONS: The proposed scheme of preoperative preparation based on a differential approach using the antihypoxant meglumine sodium demonstrated greater effectiveness than traditional treatment. The composition, volume, and duration of preoperative preparation are dependent on the state of homeostasis and the age of the patient.","PeriodicalId":437552,"journal":{"name":"Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care","volume":"98 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140713522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Ermolenko, K. V. Pshenisnov, Y. Aleksandrovich, I. V. Aleksandrovich, Alexandr I. Konev
BACKGROUND: Multiple-organ dysfunction syndrome is one of the most dangerous complications of critical illness in children, which helps determine the disease outcomes. AIM: This study aimed to examine the features of multiple-organ dysfunction syndrome in children with severe central nervous system (CNS) infection and identify factors that determine disease outcomes. MATERIALS AND METHODS: This single-center, retrospective, observational study enrolled 98 patients, which included 66 (67%) boys and 32 (33%) girls. The average age was 3.6 ± 2.5 years. The Glasgow coma scale (GCS) score was 8.8 ± 2.4 points. Shock was diagnosed in 43 (44%) patients. The average treatment duration in the intensive care unit (ICU) was 9.5 ± 6.2 days, the duration of mechanical ventilation was 6.0 ± 3.9 days, and the mortality rate was 9%. Depending on the outcome, the children were divided into groups I (recovery, n = 88) and II (death, n = 10). All indicators were recorded in the first 12 h from ICU admission. RESULTS: The most pronounced phenomena of cardiovascular dysfunction, such as decreased Teicholtz ejection fraction (62.3 L/min), were observed when the pSOFA scale score was 10 points, which was statistically significant when compared with the indicators in children with a pSOFA scale score of 8 points. In all patients, regardless of age, a negative correlation of moderate strength was found between the pSOFA scale score and the Teicholtz ejection fraction, and it was pronounced in children aged 7–17 years (R = –0.41; p = 0.008). A positive correlation was found between heart rate and pSOFA scale score in children aged 7–17 years (R = 0.72; p = 0.009). In the evaluation of the discriminatory ability of the pSOFA scale and Phoenix sepsis scores regarding the outcome on the first day of treatment in the ICU, the latter has greater prognostic significance (area under the curve, 0.866 vs 0.838; sensitivity, 76% vs 72%; specificity, 82% vs 79%). CONCLUSIONS: Low cardiac output syndrome and systemic hypoxia are key factors associated with fatal outcomes in children with severe CNS infections. The high clinical significance of the ejection fraction in predicting the outcomes of severe CNS infections in children, regardless of age, allows the use of this parameter for goal-oriented therapy.
背景：多器官功能障碍综合征是儿童危重病最危险的并发症之一，有助于决定疾病的预后。目的：本研究旨在探讨严重中枢神经系统（CNS）感染患儿多器官功能障碍综合征的特征，并确定决定疾病结局的因素。材料与方法：这项单中心、回顾性、观察性研究共纳入 98 名患者，其中包括 66 名男孩（67%）和 32 名女孩（33%）。平均年龄为 3.6 ± 2.5 岁。格拉斯哥昏迷量表（GCS）评分为（8.8 ± 2.4）分。43（44%）名患者被诊断为休克。在重症监护室（ICU）的平均治疗时间为（9.5±6.2）天，机械通气时间为（6.0±3.9）天，死亡率为 9%。根据结果，患儿被分为 I 组（康复，88 人）和 II 组（死亡，10 人）。所有指标均记录在进入重症监护室后的最初 12 小时内。结果：当pSOFA量表评分为10分时，观察到最明显的心血管功能障碍现象，如Teicholtz射血分数下降（62.3 L/min），与pSOFA量表评分为8分的患儿指标相比，具有统计学意义。在所有患者中，无论年龄大小，pSOFA评分与Teicholtz射血分数之间都存在中等强度的负相关，在7-17岁儿童中更为明显（R = -0.41; p = 0.008）。在 7-17 岁儿童中，心率与 pSOFA 评分之间呈正相关（R = 0.72；p = 0.009）。在评估 pSOFA 评分和 Phoenix 败血症评分对重症监护室第一天治疗结果的判别能力时，后者具有更大的预后意义（曲线下面积，0.866 vs 0.838；灵敏度，76% vs 72%；特异性，82% vs 79%）。结论低心输出量综合征和全身缺氧是导致严重中枢神经系统感染患儿死亡的关键因素。射血分数在预测儿童重症中枢神经系统感染的预后方面具有很高的临床意义，与年龄无关，因此可以利用这一参数进行目标导向治疗。
{"title":"Multiple-organ dysfunction in children with central nervous system infections","authors":"K. Ermolenko, K. V. Pshenisnov, Y. Aleksandrovich, I. V. Aleksandrovich, Alexandr I. Konev","doi":"10.17816/psaic1770","DOIUrl":"https://doi.org/10.17816/psaic1770","url":null,"abstract":"BACKGROUND: Multiple-organ dysfunction syndrome is one of the most dangerous complications of critical illness in children, which helps determine the disease outcomes. \u0000AIM: This study aimed to examine the features of multiple-organ dysfunction syndrome in children with severe central nervous system (CNS) infection and identify factors that determine disease outcomes. \u0000MATERIALS AND METHODS: This single-center, retrospective, observational study enrolled 98 patients, which included 66 (67%) boys and 32 (33%) girls. The average age was 3.6 ± 2.5 years. The Glasgow coma scale (GCS) score was 8.8 ± 2.4 points. Shock was diagnosed in 43 (44%) patients. The average treatment duration in the intensive care unit (ICU) was 9.5 ± 6.2 days, the duration of mechanical ventilation was 6.0 ± 3.9 days, and the mortality rate was 9%. Depending on the outcome, the children were divided into groups I (recovery, n = 88) and II (death, n = 10). All indicators were recorded in the first 12 h from ICU admission. \u0000RESULTS: The most pronounced phenomena of cardiovascular dysfunction, such as decreased Teicholtz ejection fraction (62.3 L/min), were observed when the pSOFA scale score was 10 points, which was statistically significant when compared with the indicators in children with a pSOFA scale score of 8 points. In all patients, regardless of age, a negative correlation of moderate strength was found between the pSOFA scale score and the Teicholtz ejection fraction, and it was pronounced in children aged 7–17 years (R = –0.41; p = 0.008). A positive correlation was found between heart rate and pSOFA scale score in children aged 7–17 years (R = 0.72; p = 0.009). In the evaluation of the discriminatory ability of the pSOFA scale and Phoenix sepsis scores regarding the outcome on the first day of treatment in the ICU, the latter has greater prognostic significance (area under the curve, 0.866 vs 0.838; sensitivity, 76% vs 72%; specificity, 82% vs 79%). \u0000CONCLUSIONS: Low cardiac output syndrome and systemic hypoxia are key factors associated with fatal outcomes in children with severe CNS infections. The high clinical significance of the ejection fraction in predicting the outcomes of severe CNS infections in children, regardless of age, allows the use of this parameter for goal-oriented therapy.","PeriodicalId":437552,"journal":{"name":"Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140712684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This paper describes the professional activities and merits of Sergey M. Stepanenko, a pediatric surgeon, in celebration of his anniversary.
本文介绍了小儿外科医生谢尔盖-斯捷潘年科（Sergey M. Stepanenko）的职业活动和功绩，以纪念他的诞辰。
{"title":"To the 70th anniversary of Professor Sergey M. Stepanenko","authors":"Aleksandr V. Isakov","doi":"10.17816/psaic1792","DOIUrl":"https://doi.org/10.17816/psaic1792","url":null,"abstract":"This paper describes the professional activities and merits of Sergey M. Stepanenko, a pediatric surgeon, in celebration of his anniversary.","PeriodicalId":437552,"journal":{"name":"Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care","volume":"10 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140713325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The study reported on the activities of the chief freelance specialist — pediatric surgeon of the Ministry of Health of the Russian Federation for 2023. Information was provided on the analytical and organizational work of the Institute of Chief Pediatric Surgeons, strategic decisions in pediatric surgical service, interaction with the subjects of the Russian Federation, professional associations of other specialists, and bodies of legislative and executive power of the regions and the Federation. A separate section was devoted to “Pediatric surgery: Numbers and facts”, which is a summary of the main characteristics of the pediatric surgical service of the country through comparative analysis of data from the chief pediatric surgeons of the subjects (n = 80) of the Russian Federation for 2022 and 2023.
{"title":"Report of the Chief pediatric surgeon of the Ministry of Health of the Russian Federation for 2023. Pediatric surgery: numbers and facts","authors":"D. A. Morozov","doi":"10.17816/psaic1784","DOIUrl":"https://doi.org/10.17816/psaic1784","url":null,"abstract":"The study reported on the activities of the chief freelance specialist — pediatric surgeon of the Ministry of Health of the Russian Federation for 2023. Information was provided on the analytical and organizational work of the Institute of Chief Pediatric Surgeons, strategic decisions in pediatric surgical service, interaction with the subjects of the Russian Federation, professional associations of other specialists, and bodies of legislative and executive power of the regions and the Federation. A separate section was devoted to “Pediatric surgery: Numbers and facts”, which is a summary of the main characteristics of the pediatric surgical service of the country through comparative analysis of data from the chief pediatric surgeons of the subjects (n = 80) of the Russian Federation for 2022 and 2023.","PeriodicalId":437552,"journal":{"name":"Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care","volume":"11 s2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140714823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Alexandrov, P. V. Goncharuk, L. Y. Idris, V. V. Rybchenok, Alexander A. Smirnov, R. Khagurov
Distal phalangeal traumas are among the most common injuries in children. Nowadays, no unified approach has been established for the treatment of children with distal phalangeal defects. Very few domestic publications have devoted to fingertip injuries in children. To date, one of the most common methods of treating children with distal phalangeal defects is the shortening of the finger with stump formation. In cases of distal phalangeal injuries, the most complete restoration of their length, contour, and sensitivity with the preservation of the widest range of motion, and lowest donor site morbidity are necessary. In this literature review, conservative and surgical treatments of patients with distal phalangeal defects are described. The main advantages and disadvantages of different treatment methods are highlighted. The systematic search was performed in databases of PubMed, Web of Science, eLibrary, Russian Science Citation Index, and CyberLeninka, and 86 publications devoted to the surgical treatment of patients with fingertip defects were selected. This problem and its treatment require wider coverage and introduction into domestic healthcare.
远端趾骨创伤是儿童最常见的损伤之一。目前，治疗儿童远端指骨缺损的方法尚未统一。国内很少有专门针对儿童指尖损伤的出版物。迄今为止，治疗儿童远端指骨缺损最常用的方法之一是缩短手指并形成残端。在远端指骨损伤的病例中，必须最彻底地恢复其长度、轮廓和灵敏度，同时保留最广泛的活动范围，并将供体部位的发病率降至最低。本文献综述介绍了对远端趾骨缺损患者的保守治疗和手术治疗。重点介绍了不同治疗方法的主要优缺点。我们在PubMed、Web of Science、eLibrary、Russian Science Citation Index和CyberLeninka等数据库中进行了系统检索，选取了86篇关于指尖缺损患者手术治疗的文献。这一问题及其治疗需要更广泛的覆盖面，并引入国内医疗保健领域。
{"title":"Soft tissue surgical reconstruction of distal phalanges in children. Review","authors":"A. Alexandrov, P. V. Goncharuk, L. Y. Idris, V. V. Rybchenok, Alexander A. Smirnov, R. Khagurov","doi":"10.17816/psaic1766","DOIUrl":"https://doi.org/10.17816/psaic1766","url":null,"abstract":"Distal phalangeal traumas are among the most common injuries in children. Nowadays, no unified approach has been established for the treatment of children with distal phalangeal defects. Very few domestic publications have devoted to fingertip injuries in children. To date, one of the most common methods of treating children with distal phalangeal defects is the shortening of the finger with stump formation. In cases of distal phalangeal injuries, the most complete restoration of their length, contour, and sensitivity with the preservation of the widest range of motion, and lowest donor site morbidity are necessary. In this literature review, conservative and surgical treatments of patients with distal phalangeal defects are described. The main advantages and disadvantages of different treatment methods are highlighted. The systematic search was performed in databases of PubMed, Web of Science, eLibrary, Russian Science Citation Index, and CyberLeninka, and 86 publications devoted to the surgical treatment of patients with fingertip defects were selected. This problem and its treatment require wider coverage and introduction into domestic healthcare.","PeriodicalId":437552,"journal":{"name":"Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140715103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. A. Chundokova, M. A. Golovanev, Andrey A. Ivanov
One of the causes of intussusception is the presence of Meckel’s diverticulum. Although Meckel’s diverticulum is the most common anomaly of the gastrointestinal tract, isolated cases of intussusception caused by the inversion of Meckel’s diverticulum into the lumen of the ileum have been described in world literature. Description of case. The patient was a 2-year-11-month boy who was transported by an ambulance team, with complaints of paroxysmal abdominal pain and single vomiting. Palpation revealed lower abdominal pain without signs of peritoneal irritation. The child underwent an ultrasound examination of the abdominal cavity, which revealed a layered structure consisting of the wall of the large and small intestines in the right lower quadrant. Thus, a diagnosis of intussusception was established. An attempt to conservatively straighten the intussusception during pneumoirrigoscopy was ineffective. Emergency laparoscopy was performed, and ileocecal intussusception was diagnosed, which was eliminated without technical difficulties. During the inspection of the ileum, a crater-shaped depression with a dense formation extending from it into the intestinal lumen was discovered on its antimesenteric edge 30 cm from the ileocecal angle. The operation was continued with a minilaparotomy in the right iliac region. Meckel’s diverticulum was manually inverted from the ileum, tied at the base, and cut off with the stump immersed in a purse-string suture. The postoperative period was event-free. On day 5 after the operation, the child was discharged home in a satisfactory condition. For any intussusception in children aged 1 year, the anatomical causes must be excluded, except for the possibility of an inverted Meckel’s diverticulum. Therefore, after successful intestinal disinvagination, a thorough revision of the ileum is necessary.
{"title":"Inverted Meckel’s diverticulum as a cause of intestinal intussusception in a child: A case report","authors":"M. A. Chundokova, M. A. Golovanev, Andrey A. Ivanov","doi":"10.17816/psaic1779","DOIUrl":"https://doi.org/10.17816/psaic1779","url":null,"abstract":"One of the causes of intussusception is the presence of Meckel’s diverticulum. Although Meckel’s diverticulum is the most common anomaly of the gastrointestinal tract, isolated cases of intussusception caused by the inversion of Meckel’s diverticulum into the lumen of the ileum have been described in world literature. Description of case. The patient was a 2-year-11-month boy who was transported by an ambulance team, with complaints of paroxysmal abdominal pain and single vomiting. Palpation revealed lower abdominal pain without signs of peritoneal irritation. The child underwent an ultrasound examination of the abdominal cavity, which revealed a layered structure consisting of the wall of the large and small intestines in the right lower quadrant. Thus, a diagnosis of intussusception was established. An attempt to conservatively straighten the intussusception during pneumoirrigoscopy was ineffective. Emergency laparoscopy was performed, and ileocecal intussusception was diagnosed, which was eliminated without technical difficulties. During the inspection of the ileum, a crater-shaped depression with a dense formation extending from it into the intestinal lumen was discovered on its antimesenteric edge 30 cm from the ileocecal angle. The operation was continued with a minilaparotomy in the right iliac region. Meckel’s diverticulum was manually inverted from the ileum, tied at the base, and cut off with the stump immersed in a purse-string suture. The postoperative period was event-free. On day 5 after the operation, the child was discharged home in a satisfactory condition. For any intussusception in children aged 1 year, the anatomical causes must be excluded, except for the possibility of an inverted Meckel’s diverticulum. Therefore, after successful intestinal disinvagination, a thorough revision of the ileum is necessary.","PeriodicalId":437552,"journal":{"name":"Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care","volume":"30 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140714398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lower urinary tract dysfunction occurs in 30%–55.5% of patients with cerebral palsy. The article presents a clinical example of medical rehabilitation of a child with cerebral palsy and dysfunctional urination using the verticalization method and ExoAtlet exoskeleton. Description of observation. A 15-year-old boy had urinary disorders in the form of urine leakage after urination, incomplete emptying of the bladder, episodes of enuresis, and frequent urination while sitting. The gait was unsteady and aided with crutches supported by the elbow. Examinations included uroflowmetry and electromyography. The results indicated a decrease in contractility and impaired evacuation function of the detrusor. In total, 15 rehabilitation sessions were performed using the ExoAtlet exoskeleton, after which the patient gained an independent gait supported by a cane, and the child was taught to urinate in a standing position. A repeat urological examination revealed a positive change in urination parameters with partial relief of pollakiuria and complete relief of the residual bladder volume. Verticalization and activation of striated muscles, obtained following the use of an exoskeleton in a child with cerebral palsy and dysfunctional urination, in combination with restored posture, helped normalize lower urinary tract function.
{"title":"Normalization of urination parameters in a boy with cerebral palsy after rehabilitation using an “ExoAtlet” exoskeleton","authors":"T.L. Bozhendaev, N. Guseva, Elena V. Pismennaya","doi":"10.17816/psaic1549","DOIUrl":"https://doi.org/10.17816/psaic1549","url":null,"abstract":"Lower urinary tract dysfunction occurs in 30%–55.5% of patients with cerebral palsy. The article presents a clinical example of medical rehabilitation of a child with cerebral palsy and dysfunctional urination using the verticalization method and ExoAtlet exoskeleton. Description of observation. A 15-year-old boy had urinary disorders in the form of urine leakage after urination, incomplete emptying of the bladder, episodes of enuresis, and frequent urination while sitting. The gait was unsteady and aided with crutches supported by the elbow. Examinations included uroflowmetry and electromyography. The results indicated a decrease in contractility and impaired evacuation function of the detrusor. In total, 15 rehabilitation sessions were performed using the ExoAtlet exoskeleton, after which the patient gained an independent gait supported by a cane, and the child was taught to urinate in a standing position. A repeat urological examination revealed a positive change in urination parameters with partial relief of pollakiuria and complete relief of the residual bladder volume. Verticalization and activation of striated muscles, obtained following the use of an exoskeleton in a child with cerebral palsy and dysfunctional urination, in combination with restored posture, helped normalize lower urinary tract function.","PeriodicalId":437552,"journal":{"name":"Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care","volume":"21 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140714421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Victoria A. Glushkova, A. V. Podkamenev, T. Gabrusskaya
In the last decade, the incidence of inflammatory bowel disease in children has been increasing. Some studies have reported the development of Crohn’s disease in patients with Hirschsprung disease and Hirschsprung-associated enterocolitis. Suggestions have been made about the possible causes of the development of Crohn’s-like lesions after intestinal resection in early childhood. This study aimed to summarize information about Hirschsprung-associated Crohn’s disease and Crohn’s-like lesions after surgical treatment of Hirschsprung disease. The search was carried out in scientific databases of eLibrary, PubMed, ScienceDirect, and Google Scholar. The search time interval was 2000–2023. Fourteen articles dedicated to Hirschsprung-associated Crohn’s disease were identified. Common pathogenesis factors in inflammatory bowel diseases and Hirschsprung-associated enterocolitis were identified, such as microbiota disturbance and chronic inflammation. Predisposing factors for pathological immune response to dysbiosis and incidence of enterocolitis included enteric nervous system dysfunction, impaired neuroimmune regulatory mechanisms, general immunological disturbance, and “immaturity” and abnormality of the barrier function of the intestinal mucosa. The “classic form” of Crohn’s disease may not develop in patients with Hirschsprung disease and recurrent attacks of enterocolitis but Crohn’s-like lesions. Persistent functional or organic obstruction after surgical treatment of Hirschsprung disease enhances the negative effect of predisposing factors, leading to chronic inflammation of the intestinal mucosa. Delayed occurrence of Hirschsprung-associated enterocolitis is a predisposing factor for the development of chronic inflammation. When Hirschsprung-associated enterocolitis occurs repeatedly, endoscopic assessment should be performed for the exclusion of Crohn’s disease and chronic inflammatory changes in the anastomosis area for treatment selection.
{"title":"Crohn’s disease in patients with Hirschsprung disease and Hirschsprung-associated enterocolitis: A review","authors":"Victoria A. Glushkova, A. V. Podkamenev, T. Gabrusskaya","doi":"10.17816/psaic1780","DOIUrl":"https://doi.org/10.17816/psaic1780","url":null,"abstract":"In the last decade, the incidence of inflammatory bowel disease in children has been increasing. Some studies have reported the development of Crohn’s disease in patients with Hirschsprung disease and Hirschsprung-associated enterocolitis. Suggestions have been made about the possible causes of the development of Crohn’s-like lesions after intestinal resection in early childhood. This study aimed to summarize information about Hirschsprung-associated Crohn’s disease and Crohn’s-like lesions after surgical treatment of Hirschsprung disease. The search was carried out in scientific databases of eLibrary, PubMed, ScienceDirect, and Google Scholar. The search time interval was 2000–2023. Fourteen articles dedicated to Hirschsprung-associated Crohn’s disease were identified. Common pathogenesis factors in inflammatory bowel diseases and Hirschsprung-associated enterocolitis were identified, such as microbiota disturbance and chronic inflammation. Predisposing factors for pathological immune response to dysbiosis and incidence of enterocolitis included enteric nervous system dysfunction, impaired neuroimmune regulatory mechanisms, general immunological disturbance, and “immaturity” and abnormality of the barrier function of the intestinal mucosa. The “classic form” of Crohn’s disease may not develop in patients with Hirschsprung disease and recurrent attacks of enterocolitis but Crohn’s-like lesions. Persistent functional or organic obstruction after surgical treatment of Hirschsprung disease enhances the negative effect of predisposing factors, leading to chronic inflammation of the intestinal mucosa. Delayed occurrence of Hirschsprung-associated enterocolitis is a predisposing factor for the development of chronic inflammation. When Hirschsprung-associated enterocolitis occurs repeatedly, endoscopic assessment should be performed for the exclusion of Crohn’s disease and chronic inflammatory changes in the anastomosis area for treatment selection.","PeriodicalId":437552,"journal":{"name":"Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care","volume":"47 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140713743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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