Pub Date : 2018-12-14DOI: 10.1201/9781315384313-17
A. Earl‐Slater
This article discusses the challenges faced by modern schools in providing quality education and the challenges they must overcome to address these issues. Common problems in modern schools include overloaded curriculum, technological dominance, excessive workload, and limited facilities and infrastructure. One major issue is an overloaded curriculum, where students face pressure to absorb a vast amount of information within limited timeframes, leaving little room for the development of their interests and talents. Technological dominance also has a significant impact, as excessive reliance on technology can reduce social interaction and hinder students' critical thinking abilities. Excessive workload is another commonly faced problem for students in modern schools, resulting in stress and an imbalance between academic activities and personal life. Additionally, limitations in facilities and infrastructure, such as inadequate facilities and insufficient infrastructure, can restrict students' learning experiences. The challenges faced by modern schools include the development of relevant and flexible curricula, as well as the wise integration of technology to optimize learning. Managing a balanced workload for students and improving school facilities and infrastructure are also challenges that need to be addressed. In addressing these challenges, collaboration among schools, teachers, parents, and relevant stakeholders is key. Continuous teacher training, the implementation of innovative teaching models, and adequate funding are necessary to achieve sustainable improvements in education. Through a deep understanding of the problems faced by modern schools and the challenges they encounter, it is hoped that this article will provide valuable insights for stakeholders in addressing educational issues and promoting better progress for students and society as a whole.
{"title":"Q","authors":"A. Earl‐Slater","doi":"10.1201/9781315384313-17","DOIUrl":"https://doi.org/10.1201/9781315384313-17","url":null,"abstract":"This article discusses the challenges faced by modern schools in providing quality education and the challenges they must overcome to address these issues. Common problems in modern schools include overloaded curriculum, technological dominance, excessive workload, and limited facilities and infrastructure. One major issue is an overloaded curriculum, where students face pressure to absorb a vast amount of information within limited timeframes, leaving little room for the development of their interests and talents. Technological dominance also has a significant impact, as excessive reliance on technology can reduce social interaction and hinder students' critical thinking abilities. Excessive workload is another commonly faced problem for students in modern schools, resulting in stress and an imbalance between academic activities and personal life. Additionally, limitations in facilities and infrastructure, such as inadequate facilities and insufficient infrastructure, can restrict students' learning experiences. The challenges faced by modern schools include the development of relevant and flexible curricula, as well as the wise integration of technology to optimize learning. Managing a balanced workload for students and improving school facilities and infrastructure are also challenges that need to be addressed. In addressing these challenges, collaboration among schools, teachers, parents, and relevant stakeholders is key. Continuous teacher training, the implementation of innovative teaching models, and adequate funding are necessary to achieve sustainable improvements in education. Through a deep understanding of the problems faced by modern schools and the challenges they encounter, it is hoped that this article will provide valuable insights for stakeholders in addressing educational issues and promoting better progress for students and society as a whole.","PeriodicalId":438532,"journal":{"name":"Dictionary of Health Economics","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129895342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-14DOI: 10.1201/9781315384313-19
A. Earl‐Slater
{"title":"S","authors":"A. Earl‐Slater","doi":"10.1201/9781315384313-19","DOIUrl":"https://doi.org/10.1201/9781315384313-19","url":null,"abstract":"","PeriodicalId":438532,"journal":{"name":"Dictionary of Health Economics","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126664774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-14DOI: 10.1201/9781315384313-13
A. Earl‐Slater
{"title":"M","authors":"A. Earl‐Slater","doi":"10.1201/9781315384313-13","DOIUrl":"https://doi.org/10.1201/9781315384313-13","url":null,"abstract":"","PeriodicalId":438532,"journal":{"name":"Dictionary of Health Economics","volume":"173 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132663654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-14DOI: 10.1201/9781315384313-18
A. Earl‐Slater
As a sensor of cytosolic DNA, the role of cyclic GMP-AMP synthase (cGAS) in innate immune response is well established, yet how its functions in different biological conditions remain to be elucidated. Here, we identify cGAS as an essential regulator in inhibiting mitotic DNA double-strand break (DSB) repair and protecting short telomeres from end-to-end fusion independent of the canonical cGAS-STING pathway. cGAS associates with telomeric/subtelomeric DNA during mitosis when TRF1/ TRF2/POT1 are de fi cient on telomeres. Depletion of cGAS leads to mitotic chromosome end-to-end fusions predominantly occurring between short telomeres. Mechanistically, cGAS interacts with CDK1 and posi-tions them to chromosome ends. Thus, CDK1 inhibits mitotic non-homologous end joining (NHEJ) by blocking the recruitment of RNF8. cGAS-de fi cient human primary cells are defective in entering replicative senescence and display chromosome end-to-end fusions, genome instability and prolonged growth arrest. Altogether, cGAS safeguards genome stability by controlling mitotic DSB repair to inhibit mitotic chromosome end-to-end fusions, thus facilitating replicative senescence
{"title":"R","authors":"A. Earl‐Slater","doi":"10.1201/9781315384313-18","DOIUrl":"https://doi.org/10.1201/9781315384313-18","url":null,"abstract":"As a sensor of cytosolic DNA, the role of cyclic GMP-AMP synthase (cGAS) in innate immune response is well established, yet how its functions in different biological conditions remain to be elucidated. Here, we identify cGAS as an essential regulator in inhibiting mitotic DNA double-strand break (DSB) repair and protecting short telomeres from end-to-end fusion independent of the canonical cGAS-STING pathway. cGAS associates with telomeric/subtelomeric DNA during mitosis when TRF1/ TRF2/POT1 are de fi cient on telomeres. Depletion of cGAS leads to mitotic chromosome end-to-end fusions predominantly occurring between short telomeres. Mechanistically, cGAS interacts with CDK1 and posi-tions them to chromosome ends. Thus, CDK1 inhibits mitotic non-homologous end joining (NHEJ) by blocking the recruitment of RNF8. cGAS-de fi cient human primary cells are defective in entering replicative senescence and display chromosome end-to-end fusions, genome instability and prolonged growth arrest. Altogether, cGAS safeguards genome stability by controlling mitotic DSB repair to inhibit mitotic chromosome end-to-end fusions, thus facilitating replicative senescence","PeriodicalId":438532,"journal":{"name":"Dictionary of Health Economics","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124228923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"H","authors":"A. Earl‐Slater","doi":"10.1201/9781315384313-8","DOIUrl":"https://doi.org/10.1201/9781315384313-8","url":null,"abstract":"","PeriodicalId":438532,"journal":{"name":"Dictionary of Health Economics","volume":"179 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115008690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-14DOI: 10.1201/9781315384313-15
A. Earl‐Slater
{"title":"O","authors":"A. Earl‐Slater","doi":"10.1201/9781315384313-15","DOIUrl":"https://doi.org/10.1201/9781315384313-15","url":null,"abstract":"","PeriodicalId":438532,"journal":{"name":"Dictionary of Health Economics","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128699135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-14DOI: 10.1201/9781315384313-23
A. Earl‐Slater
{"title":"W","authors":"A. Earl‐Slater","doi":"10.1201/9781315384313-23","DOIUrl":"https://doi.org/10.1201/9781315384313-23","url":null,"abstract":"","PeriodicalId":438532,"journal":{"name":"Dictionary of Health Economics","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121768756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-14DOI: 10.1201/9781315384313-25
A. Earl‐Slater
Para poner en marcha una estrategia de comunicación debes tener claros los contenidos que deseas transmitir. Y para ello, necesitamos previamente manejar abundante información: listados de empresas, información profesional, ofertas de trabajo, etc. En definitiva, estar al día en lo que sucede en nuestro entorno profesional. Eso requiere realizar búsquedas eficaces y usar mecanismos para su adecuada organización.
{"title":"Y","authors":"A. Earl‐Slater","doi":"10.1201/9781315384313-25","DOIUrl":"https://doi.org/10.1201/9781315384313-25","url":null,"abstract":"Para poner en marcha una estrategia de comunicación debes tener claros los contenidos que deseas transmitir. Y para ello, necesitamos previamente manejar abundante información: listados de empresas, información profesional, ofertas de trabajo, etc. En definitiva, estar al día en lo que sucede en nuestro entorno profesional. Eso requiere realizar búsquedas eficaces y usar mecanismos para su adecuada organización.","PeriodicalId":438532,"journal":{"name":"Dictionary of Health Economics","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129869890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-14DOI: 10.1201/9781315384313-14
A. Earl‐Slater
VISTO il D.P.R. 10 Gennaio 1957, n. 3; VISTO il D.P.R. 3.5.1957, n. 686; VISTA la Legge 9.5.1989, n. 168; VISTA la Legge 7.8.1990, n. 241; VISTA la Legge 10.4.1991, n. 125; VISTA la Legge 5.2.1992, n. 104; VISTA la Legge 24.12.1993, n. 537 ed in particolare l’art. 5; VISTO il D.P.C.M. 7.2.1994, n. 174; VISTO il D.P.R. 9.5.1994, n. 487 e successive modificazioni ed integrazioni; VISTA la Legge 31 Dicembre 1996, n. 675 e successive modificazione ed integrazioni; VISTA la Legge 15 Maggio 1997, n. 127; VISTO il D.P.R. 28.12.2000, n. 445; VISTO il D.Lgs. 30.3.2001, n. 165 e successive modificazioni ed integrazioni; VISTO il Contratto Collettivo Nazionale dei Dipendenti del comparto dell’Università 20062009; VISTO il Contratto Collettivo Nazionale di Lavoro relativo al Personale del Comparto Istruzione e Ricerca Triennio 2016-2018; VISTO il D.Lgs. 15 marzo 2010, n. 66 Codice dell’ordinamento militare ed in particolare gli artt. 1014 comma 1 e 678 comma 9 (già D. Lgs. 215/2001, art. 18 comma 6); VISTO il Regolamento in materia di accesso dall'esterno ai ruoli del personale tecnicoamministrativo a tempo indeterminato di questa Università approvato con D.R. 4 aprile 2017, n. 495; VISTA la Legge 16.1.2003, n. 3; VISTO il Regolamento (UE) 2016/679 del Parlamento europeo e del Consiglio del 27 aprile 2016 relativo alla protezione delle persone fisiche con riguardo al trattamento dei dati personali, nonché alla libera circolazione di tali dati e che abroga la direttiva 95/46/CE; VISTA la Legge 12 ottobre 1993 n. 413, Norme sull'obiezione di coscienza alla sperimentazione animale; VISTO l’avviso di mobilità volontaria ai sensi dell’art. 30 del Decreto Legislativo 30 marzo 2001, n. 165 e ai sensi dell’art. 57 del C.C.N.L. 2006-2009 del personale del comparto Università pubblicato all’Albo ufficiale di Ateneo Rep. n. 568/2022 Prot n. 245865 del 29/07/2022; CONSIDERATO che con nota Prot. 248281 del 01/08/2022 è stato data attuazione a quanto disposto dall'art. dall'art. 34 bis del Decreto Legislativo 30 marzo 2001, n. 165; VISTO il Decreto del Direttore Generale n. 1175/2022 Prot n. 244063 del 27/07/2022; VISTO il Decreto legge 1 aprile 2021, n. 44; ACCERTATA la copertura finanziaria sul bilancio dell’Ateneo; VISTO lo Statuto dell’Università degli Studi di Ferrara;
{"title":"N","authors":"A. Earl‐Slater","doi":"10.1201/9781315384313-14","DOIUrl":"https://doi.org/10.1201/9781315384313-14","url":null,"abstract":"VISTO il D.P.R. 10 Gennaio 1957, n. 3; VISTO il D.P.R. 3.5.1957, n. 686; VISTA la Legge 9.5.1989, n. 168; VISTA la Legge 7.8.1990, n. 241; VISTA la Legge 10.4.1991, n. 125; VISTA la Legge 5.2.1992, n. 104; VISTA la Legge 24.12.1993, n. 537 ed in particolare l’art. 5; VISTO il D.P.C.M. 7.2.1994, n. 174; VISTO il D.P.R. 9.5.1994, n. 487 e successive modificazioni ed integrazioni; VISTA la Legge 31 Dicembre 1996, n. 675 e successive modificazione ed integrazioni; VISTA la Legge 15 Maggio 1997, n. 127; VISTO il D.P.R. 28.12.2000, n. 445; VISTO il D.Lgs. 30.3.2001, n. 165 e successive modificazioni ed integrazioni; VISTO il Contratto Collettivo Nazionale dei Dipendenti del comparto dell’Università 20062009; VISTO il Contratto Collettivo Nazionale di Lavoro relativo al Personale del Comparto Istruzione e Ricerca Triennio 2016-2018; VISTO il D.Lgs. 15 marzo 2010, n. 66 Codice dell’ordinamento militare ed in particolare gli artt. 1014 comma 1 e 678 comma 9 (già D. Lgs. 215/2001, art. 18 comma 6); VISTO il Regolamento in materia di accesso dall'esterno ai ruoli del personale tecnicoamministrativo a tempo indeterminato di questa Università approvato con D.R. 4 aprile 2017, n. 495; VISTA la Legge 16.1.2003, n. 3; VISTO il Regolamento (UE) 2016/679 del Parlamento europeo e del Consiglio del 27 aprile 2016 relativo alla protezione delle persone fisiche con riguardo al trattamento dei dati personali, nonché alla libera circolazione di tali dati e che abroga la direttiva 95/46/CE; VISTA la Legge 12 ottobre 1993 n. 413, Norme sull'obiezione di coscienza alla sperimentazione animale; VISTO l’avviso di mobilità volontaria ai sensi dell’art. 30 del Decreto Legislativo 30 marzo 2001, n. 165 e ai sensi dell’art. 57 del C.C.N.L. 2006-2009 del personale del comparto Università pubblicato all’Albo ufficiale di Ateneo Rep. n. 568/2022 Prot n. 245865 del 29/07/2022; CONSIDERATO che con nota Prot. 248281 del 01/08/2022 è stato data attuazione a quanto disposto dall'art. dall'art. 34 bis del Decreto Legislativo 30 marzo 2001, n. 165; VISTO il Decreto del Direttore Generale n. 1175/2022 Prot n. 244063 del 27/07/2022; VISTO il Decreto legge 1 aprile 2021, n. 44; ACCERTATA la copertura finanziaria sul bilancio dell’Ateneo; VISTO lo Statuto dell’Università degli Studi di Ferrara;","PeriodicalId":438532,"journal":{"name":"Dictionary of Health Economics","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125593122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-14DOI: 10.1201/9781315384313-26
A. Earl‐Slater
{"title":"Z","authors":"A. Earl‐Slater","doi":"10.1201/9781315384313-26","DOIUrl":"https://doi.org/10.1201/9781315384313-26","url":null,"abstract":"","PeriodicalId":438532,"journal":{"name":"Dictionary of Health Economics","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129319918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}