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Das akute Abdomen in der Schwangerschaft 妊娠急腹症
Q4 Medicine Pub Date : 2022-01-07 DOI: 10.1007/s00129-021-04897-z
Henriette Schallock, M. Huber
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引用次数: 0
Gutartige Tumoren der weiblichen Brust: vergleichen – versorgen – verstehen 女性乳房良性肿瘤:对症杂交
Q4 Medicine Pub Date : 2022-01-04 DOI: 10.1007/s00129-021-04885-3
A. Strauss
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引用次数: 0
[Online congress of the German Menopause Society 2021]. [2021年德国更年期学会在线大会]。
Q4 Medicine Pub Date : 2022-01-01 Epub Date: 2022-03-17 DOI: 10.1007/s00129-022-04908-7
Anne Göttenauer
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引用次数: 0
Vorteile der 3-D/4-D-Echokardiographie – Neuerungen und Ausblick 3d /4 d心电图革新和前景的优势
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.1007/s00129-021-04891-5
A. Weichert, Sven C. Weber
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引用次数: 0
Medizinrecht 医学法
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.1007/s00129-021-04888-0
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引用次数: 0
Kardiale Funktionsanalyse beim Feten: Schritt für Schritt 引擎操纵术检查
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.1007/s00129-021-04889-z
O. Graupner, C. Enzensberger
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引用次数: 2
[Radiotherapy for the treatment of leukemia]. 放疗治疗白血病。
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.1007/s00761-022-01163-2
Michael Oertel, Hans Theodor Eich

Background: Lymphoma cells are highly radiosensitive and consequently, radiation therapy is a rational addition to systemic therapy in the treatment of leukemia. Especially as a conditioning regimen before allogeneic stem cell transplantation, radiation therapy, in the form of total body irradiation, is an established concept.

Objectives: The present work provides an overview on the execution and side effects of radiation treatment in leukemia. Especially (long-term) side effects after total body irradiation are presented.

Materials and methods: A selective search in the database PubMed on radiation treatment of leukemia and on total body irradiation has been carried out, focusing on toxicities as well as technical and conceptional innovations.

Results: Total body irradiation is a successful conditioning therapy before allogeneic stem cell transplantation and is accompanied by a diverse, but manageable, toxicity spectrum with endocrinological, cardiopulmonary, ophthalmological, nephrological and neurological long-term side effects as well as secondary neoplasia. In addition, low-dose radiotherapy may be utilized to treat myeloid sarcoma (chloroma).

Conclusions: The variety of side effects after total body irradiation requires an interdisciplinary and long-term aftercare provided by radiation oncologists and medical oncologists/the transplantation team. Technical evolutions may result in a more selective targeting of the bone marrow and lymphatic organs. At the moment, these techniques are not established in clinical routine but are being evaluated in clinical trials.

背景:淋巴瘤细胞对放射高度敏感,因此,放射治疗是白血病治疗系统治疗的合理补充。特别是作为同种异体干细胞移植前的调理方案,放射治疗,以全身照射的形式,是一个既定的概念。目的:对白血病放射治疗的实施和副作用进行综述。特别是(长期)副作用的全身照射后提出。材料和方法:在PubMed数据库中对白血病的放射治疗和全身照射进行了选择性搜索,重点是毒性以及技术和概念上的创新。结果:全身照射是同种异体干细胞移植前的一种成功的调理疗法,并伴有多种但可控的毒性谱,包括内分泌、心肺、眼科、肾脏和神经系统的长期副作用以及继发性肿瘤。此外,低剂量放疗可用于髓系肉瘤(氯瘤)的治疗。结论:全身照射后的各种副作用需要放射肿瘤学家和医学肿瘤学家/移植团队提供跨学科和长期的善后护理。技术的发展可能导致骨髓和淋巴器官更有选择性的靶向。目前,这些技术尚未在临床常规中建立,但正在临床试验中进行评估。
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引用次数: 1
Fetale Arrhythmien – ein Update 胎儿心律不整最新情况
Q4 Medicine Pub Date : 2021-12-22 DOI: 10.1007/s00129-021-04887-1
U. Gembruch
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引用次数: 0
Geburtsplanung bei Diabetes in der Schwangerschaft 怀孕时有糖尿病的生育计划
Q4 Medicine Pub Date : 2021-12-22 DOI: 10.1007/s00129-021-04893-3
I. Hösli, K. Redling
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引用次数: 0
Update fetale Therapie bei kardialen Vitien 呼吸困难
Q4 Medicine Pub Date : 2021-12-22 DOI: 10.1007/s00129-021-04892-4
B. Strizek, C. Berg
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引用次数: 0
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