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The Knowledge and Attitudes of University Students concerning HPV Vaccine and Cervical Screening 大学生对HPV疫苗和子宫颈筛查的知识和态度
Pub Date : 2009-01-01 DOI: 10.4137/CMRH.S2973
L. Elit, K. Trim, R. Mohan, S. Nastos, D. Harnish
Background Cervical cancer is preventable with regular PAP tests and the human papillomavirus (HPV) vaccine. Objective Identify factors influencing initiation into regular sexual health examinations within a group of undergraduate health science students who have high parental SES. Methods After reviewing the literature, a survey of knowledge, attitudes and behaviors about HPV exposure and cervical cancer prevention through vaccination and cervical cancer screening was developed. The survey was circulated using a web-based survey tool to undergraduate Faculty of Health Sciences student. Results Two hundred and three students at McMaster University completed the survey. The sample included 72% women and 28% men. The mean age was 19.4 years. This sample represents a population of young adults who the previous literature would suggest are most likely to have regular health care since they are affluent (FAS greater than 6.7 ∓ 1.4). This group is also motivated in health education as 83.3% knew about the HPV vaccine and 76.4% could define the purpose of a PAP smear. Both male and female students were more likely to consult their family doctor about sexual health than their family. More than half of sexually active females have a family doctor, 82.1% of which visit them regularly. Sexually active women visit more regularly than sexually inactive women (p ≤ 0.01). The majority (66%) are comfortable discussing sexual health with their family doctor, yet only 62.5% of women have had this discussion. 57% of sexually active women and less that 1% of non-sexually active women had had a PAP smear or a pelvic exam. Conclusion These affluent and well educated students do not appear to be able to apply their knowledge of HPV and PAP smears to their own sexual health. Thus they require access to tools that help motivate university students to personalize information and make important health decisions.
背景宫颈癌可以通过定期的PAP检查和人乳头瘤病毒(HPV)疫苗来预防。目的探讨影响父母社会经济地位高的健康科学本科学生接受定期性健康检查的因素。方法在查阅文献的基础上,对HPV暴露及通过疫苗接种和宫颈癌筛查预防宫颈癌的知识、态度和行为进行调查。该调查使用基于网络的调查工具分发给健康科学学院的本科生。结果麦克马斯特大学的203名学生完成了调查。样本包括72%的女性和28%的男性。平均年龄为19.4岁。该样本代表了先前文献认为最有可能有定期医疗保健的年轻人群体,因为他们富裕(FAS大于6.7 + 1.4)。这一群体也积极参与健康教育,因为83.3%的人知道HPV疫苗,76.4%的人可以确定PAP涂片的目的。男女学生都比家人更倾向于向家庭医生咨询性健康问题。超过一半的性活跃女性有家庭医生,其中82.1%的人定期去看她们。性生活活跃的女性就诊频率高于性生活不活跃的女性(p≤0.01)。大多数人(66%)愿意与家庭医生讨论性健康问题,但只有62.5%的女性进行过这样的讨论。57%的性活跃女性和不到1%的非性活跃女性做过子宫颈抹片检查或盆腔检查。结论这些富裕和受过良好教育的学生似乎不能将他们对HPV和PAP涂片的知识应用到自己的性健康中。因此,他们需要使用工具来帮助激励大学生个性化信息并做出重要的健康决定。
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引用次数: 7
Coping and Suicidal Ideations in Women with Symptoms of Postpartum Depression 产后抑郁症患者的应对与自杀意念
Pub Date : 2009-01-01 DOI: 10.4137/CMRH.S3801
S. Doucet, N. Letourneau
Objective To explore the relationship between coping mechanisms and suicidal ideations among women who experience symptoms of postpartum depression. Design This exploratory descriptive study used secondary data from a study of women who experienced symptoms of postpartum depression. Participants Convenience and purposive sampling were used to obtain the community sample of 40 women who experienced symptoms of postpartum depression. Methods Binary logistic regression was employed to explore emotion-focused coping, avoidance-focused coping, problem-focused coping, and religious coping as predictors of suicidal ideations. Results Approximately 27% of the sample reported suicidal ideations within the past seven days. The results showed that lower levels of emotion-focused coping and higher levels of avoidance-focused and religious coping predicted suicidal ideations in participants. Problem-focused coping did not predict suicidal ideations. Conclusion Overall, our findings provide support for the importance of coping mechanisms as predictors of suicidal ideations among women who experience symptoms of postpartum depression. The results illustrate the need for health professionals to conduct routine assessments on coping strategies and thoughts of suicide when caring for postpartum women, as well as the need to integrate coping approaches in the prevention and treatment of suicidal ideations.
目的探讨产后抑郁症患者应对机制与自杀意念的关系。设计:本探索性描述性研究采用了一项对经历过产后抑郁症状的妇女的研究的辅助数据。采用方便抽样和目的抽样的方法,对40名有产后抑郁症状的妇女进行社区抽样。方法采用二元logistic回归方法探讨情绪聚焦应对、回避聚焦应对、问题聚焦应对和宗教应对对自杀意念的影响。结果约27%的样本报告在过去7天内有自杀意念。结果表明,较低水平的情绪聚焦应对和较高水平的回避聚焦应对和宗教应对预测了参与者的自杀意念。以问题为中心的应对与自杀意念无关。结论:总的来说,我们的研究结果支持应对机制作为产后抑郁症妇女自杀意念预测因素的重要性。结果表明,在护理产后妇女时,卫生专业人员需要对应对策略和自杀想法进行常规评估,并需要将应对方法整合到自杀意念的预防和治疗中。
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引用次数: 12
Introductory Editorial 入门篇社论
Pub Date : 2008-01-01 DOI: 10.1177/117955810800100001
Z. Blumenfeld
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引用次数: 0
Obesity and Time to Conception 肥胖与受孕时间
Pub Date : 2008-01-01 DOI: 10.4137/CMRH.S869
S. Richman
Objective To examine the association between body mass index and time to conception. Methods Secondary data analysis of The Asthma in Pregnancy Study, a Prospective cohort of 2205 women assembled from April 1997-June 2000. Results Time to conception in women not on contraception, by BMI category, did not show a significant difference among the groups, p = 0.81 for test of equality over the strata. Conclusions No association between time to conception and BMI was demonstrated in these data.
目的探讨体重指数与受孕时间的关系。方法对1997年4月至2000年6月期间2205名妊娠期哮喘妇女的前瞻性队列进行二次资料分析。结果未采取避孕措施的妇女的受孕时间,按BMI分类,各组间无显著差异,在阶层平等检验中p = 0.81。结论:在这些数据中,受孕时间与BMI之间没有关联。
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引用次数: 4
Contraceptive Options for the Perimenopausal Woman 围绝经期妇女的避孕选择
Pub Date : 2008-01-01 DOI: 10.4137/CMRH.S886
Petra M. Casey, M. Marnach, S. Pruthi
Introduction Despite an increasing number of available contraceptive options, about 49% of the annual U.S. pregnancies remain unintended.1 Surprisingly, over a third of all pregnancies in women in their forties are unintended. Perhaps due to safety considerations and co-existing medical conditions, these patients may be directed toward less effective, compliance dependent methods. In addition to reliable contraception, perimenopausal women may need to stabilize hormonal fl uctuations and minimize irregular heavy menstrual fl ow. The ideal contraceptive for the perimenopausal woman would be compliance independent and provide non-contraceptive benefi ts. With the perimenopausal woman’s needs in mind , we will discuss all contraceptive options currently available in the United States, review the risks and benefi ts of each and describe the transition from contraception to postmenopausal hormone therapy. We include a summary of the effi cacy of various contraceptives in Table 1. As women enter their perimenopausal years, they are often faced with contraceptive decisions along with the onset of new medical conditions. These conditions include cardiovascular risk factors such as hyperlipidemia, hypertension, diabetes and obesity. Cardiovascular disease increases dramatically with age and is the leading cause of death among adult women in the U.S. Cardiovascular risk factor management is therefore a critical component in the care of perimenopausal women. It is prudent to educate women seeking contraceptive counseling about the importance of a healthy diet, exercise and avoidance of smoking. It is known that coronary artery disease in women who undergo natural menopause occurs about 10 years later than men. However, women who undergo early natural menopause or bilateral oophorectomy develop coronary artery disease at a younger age. The decline in ovarian function is related to changes in the lipid profi le and subsequent risk for developing coronary artery disease.2 Studies have not shown an increased risk of myocardial infarction or stroke in women who are current users of oral contraceptives containing less than 50 ug of EE.3 However, women older than 35 years of age who smoke and have a history of hypertension are at increased risk for myocardial infarction and stroke.4 Women with a history of diabetes but no other risk factors such as hypertension or vascular disease including nephropathy are candidates for combination oral contraceptives. Those who have diabetes in addition to multiple other cardiac risk factors should be offered progestin only or nonhormonal contraceptives. In short, from the standpoint of medical eligibility, combination estrogen-progestin contraception is most appropriate for lean, healthy, non-smoking women without signifi cant cardiovascular risk factors. Women with multiple cardiovascular risk factors are ineligible for combination estrogen-progestin contraceptives. These women need to be counseled regarding a healthy lifestyl
尽管可用的避孕方法越来越多,但美国每年约有49%的怀孕仍然是意外怀孕令人惊讶的是,在40多岁的女性中,超过三分之一的怀孕是意外的。可能由于安全考虑和共存的医疗条件,这些患者可能会被引导到效果较差的依从性依赖方法。除了可靠的避孕措施,围绝经期妇女可能需要稳定激素波动,尽量减少不规则的大量月经。对于围绝经期妇女来说,理想的避孕方法是独立于依从性的,并提供非避孕的好处。考虑到围绝经期妇女的需要,我们将讨论目前在美国可用的所有避孕方法,回顾每种方法的风险和好处,并描述从避孕到绝经后激素治疗的过渡。我们在表1中对各种避孕药具的疗效进行了总结。当妇女进入围绝经期时,她们常常面临着避孕的决定以及新的医疗条件的出现。这些疾病包括心血管危险因素,如高脂血症、高血压、糖尿病和肥胖。心血管疾病随着年龄的增长而急剧增加,是美国成年妇女死亡的主要原因,因此心血管风险因素管理是围绝经期妇女护理的关键组成部分。谨慎的做法是教育寻求避孕咨询的妇女了解健康饮食、锻炼和避免吸烟的重要性。众所周知,自然绝经的女性患冠状动脉疾病的时间比男性晚10年左右。然而,接受早期自然绝经或双侧卵巢切除术的妇女在较年轻时患上冠状动脉疾病。卵巢功能的下降与血脂变化和随后发生冠状动脉疾病的风险有关研究并没有显示,目前口服避孕药中含有少于50微克ee3的女性心肌梗死或中风的风险增加。然而,35岁以上吸烟且有高血压史的女性心肌梗死和中风的风险增加有糖尿病史但没有其他危险因素如高血压或血管疾病包括肾病的妇女适合联合口服避孕药。那些患有糖尿病和其他多种心脏危险因素的人应该只服用黄体酮或非激素避孕药。简而言之,从医疗资格的角度来看,雌激素-黄体酮联合避孕最适合瘦、健康、不吸烟、没有明显心血管危险因素的女性。有多种心血管危险因素的妇女不适合使用雌激素-黄体酮联合避孕药。这些妇女需要得到关于健康生活方式和风险因素管理的咨询,最好只提供黄体酮或非激素避孕药
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引用次数: 0
Endometrial Thickness- a Practical Prospective Marker for the Risk of Surgical Intervention after RU486 Induced Abortion 子宫内膜厚度——RU486人工流产后手术干预风险的实用前瞻性指标
Pub Date : 2008-01-01 DOI: 10.4137/CMRH.S994
Z. Blumenfeld, W. Abdallah, D. Kaplan, O. Nevo
Background Medical termination of pregnancy [TOP] during the early first trimester is commonly used. However, treatment failure which warrants surgical intervention occurs in small proportion of patients. Our objective was to examine the effectiveness and predictive value of sonographic measurement of endometrial thickness during a follow up visit after medical abortion as an accurate predictor of the necessity of curettage for completion of pregnancy termination. Methods Women who opted for medical TOP where treated by single dose of RU486 followed by a single dose of misoprostol. Endometrial thickness was evaluated by transvaginal U.S. at 14 days after misoprostol tretament. The data was collected prospectively for this cohort study which includes all the women undergoing medical abortion in the first seven weeks of gestation. Results In 34.7% of the patients the endometrial width was > 11 mm on the follow-up visit. Surgical intervention was performed in 18% of these patients, for a failure rate of the medical termination of pregnancy [TOP] of 6.25%, as compared with no failure rate in those with endometrium < 11 mm, P < 0.001. In the patients where the endometrium was 11-12 mm on follow-up, the failure rate was 5%, and if > 12 mm the failure was 5.9%. In cases where the endometrium was 12-13 mm the failure rate was 27.3%, and if >13 mm the failure was 18.9%. When the endometrium was 13-14 mm the failure rate was 10%, and when >14 mm the failure was 23.7%. Half of the 18 patients who had undergone dilatation and curettage [D&C] for completion of the TOP, had endometrium > 14 mm, one to two weeks after the medical abortion. Conclusion Measurement of endometrial width after medical TOP is beneficial in segregating patient to low or high risk for surgical treatment of retained product of conception [POC]. Using a cutoff of 11 mm during the follow-up visit after medical TOP, 18% of the patients may need dilatation and curettage to complete the pregnancy termination, and if it is >14 mm, half of them may need surgical intervention. There is no difference between 11 and 14 mm regarding the risk of surgical intervention after medical TOP.
背景医学终止妊娠[TOP]在妊娠早期是常用的。然而,需要手术干预的治疗失败发生在一小部分患者中。我们的目的是研究在药物流产后随访期间超声测量子宫内膜厚度的有效性和预测价值,作为完成终止妊娠的刮除必要性的准确预测指标。方法选择医学TOP的妇女采用单剂量RU486加单剂量米索前列醇治疗。米索前列醇治疗14天后,经阴道超声检查子宫内膜厚度。这项队列研究的数据是前瞻性收集的,其中包括所有在妊娠前七周进行药物流产的妇女。结果34.7%的患者随访时子宫内膜宽度为1011mm。其中18%的患者进行了手术干预,药物终止妊娠的失败率[TOP]为6.25%,而子宫内膜< 11 mm的患者无失败率,P < 0.001。随访时子宫内膜11- 12mm的患者失败率为5%,子宫内膜0 - 12mm的患者失败率为5.9%。子宫内膜在12-13毫米的病例中,失败率为27.3%,如果子宫内膜在12-13毫米,失败率为18.9%。子宫内膜13 ~ 14 mm时,失败率为10%;子宫内膜10 ~ 14 mm时,失败率为23.7%。18例经扩张刮除术(D&C)完成TOP的患者中,半数在药物流产后1 ~ 2周出现子宫内膜bbb14 mm。结论医用TOP后测量子宫内膜宽度有助于区分低风险或高风险患者进行妊娠残留物手术治疗[POC]。医疗TOP术后随访时截距为11mm, 18%的患者可能需要扩张刮除完成终止妊娠,若截距为14mm,半数患者可能需要手术干预。11 mm和14 mm在医学TOP后手术干预的风险方面没有差异。
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引用次数: 3
Editorial—Recent Developments in Clinical Medicine: Reproductive Health 社论-临床医学的最新发展:生殖健康
Pub Date : 2008-01-01 DOI: 10.1177/117955810800200001
Z. Blumenfeld
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引用次数: 0
In Vitro Models Using the Human Placenta to Study Fetal Exposure to Drugs 利用人胎盘研究胎儿药物暴露的体外模型
Pub Date : 2008-01-01 DOI: 10.4137/CMRH.S974
M. Kovo, A. Golan
Over the recent years there has been a gradual rise in the use of pharmaceuticals during pregnancy. Knowledge on placental drug transfer and metabolism has increased during the past decades as well. Investigation of the transplacental transfer of any therapeutically useful drug is essential to the understanding of its metabolic processes and is a prerequisite for its use during pregnancy. The purpose of this review is to give insight on the various techniques that have been developed to evaluate transplacental transfer of drugs and xenobiotics.
近年来,怀孕期间使用药物的情况逐渐增加。在过去的几十年里,关于胎盘药物转移和代谢的知识也有所增加。研究任何治疗药物的经胎盘转移对了解其代谢过程至关重要,也是妊娠期间使用药物的先决条件。本综述的目的是对已经开发的用于评估药物和外源性药物经胎盘转移的各种技术进行深入了解。
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引用次数: 18
期刊
Clinical Medicine Insights-Reproductive Health
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