Radiation dermatitis (RD) is an acute skin reaction that occurs as a result of radiotherapy used to treat a range of different cancers. Severity of symptoms ranges from erythema to dry desquamation (dry flaky skin with itching) to moist desquamation (serous exudate, oedema and blistering). Level 1 evidence1-3 reporting effectiveness of barrier films for preventing RD. Some studies2-4 showed statistically significant reductions in severity of RD and reduction in patient-reported symptoms.; however, the volume of evidence was small. Largest effect was achieved with a silicone-based barrier film forming gel dressing that was associated with a 41% reduction in risk of grade 2 RD.4 Level 1 and 3 evidence4, 5 failed to demonstrate a benefit in using a barrier film to treat existing RD.
{"title":"Barrier film for prevention and treatment of radiation dermatitis: a WHAM evidence summary","authors":"E. Haesler","doi":"10.33235/wpr.30.1.62-64","DOIUrl":"https://doi.org/10.33235/wpr.30.1.62-64","url":null,"abstract":"Radiation dermatitis (RD) is an acute skin reaction that occurs as a result of radiotherapy used to treat a range of different cancers. Severity of symptoms ranges from erythema to dry desquamation (dry flaky skin with itching) to moist desquamation (serous exudate, oedema and blistering). Level 1 evidence1-3 reporting effectiveness of barrier films for preventing RD. Some studies2-4 showed statistically significant reductions in severity of RD and reduction in patient-reported symptoms.; however, the volume of evidence was small. Largest effect was achieved with a silicone-based barrier film forming gel dressing that was associated with a 41% reduction in risk of grade 2 RD.4 Level 1 and 3 evidence4, 5 failed to demonstrate a benefit in using a barrier film to treat existing RD.","PeriodicalId":44572,"journal":{"name":"Wound Practice and Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42843768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The nails, in combination with skin, glands and hair, comprise the integumentary system. Abnormalities in the colour, shape and clinical appearance of nails can be indicative of pathophysiological disorders, habit-tics such as bitten nails, poor grooming, nutritional deficits and cosmetic practices. Discolouration and changes in nail appearance are common reasons for referral of individuals to dermatologists. This paper presents a mélange of common nail disorders with a clinical focus on those that present with discolouration.
{"title":"Discoloured nails","authors":"Kurt Gebauer, K. Carville","doi":"10.33235/wpr.30.1.50-54","DOIUrl":"https://doi.org/10.33235/wpr.30.1.50-54","url":null,"abstract":"The nails, in combination with skin, glands and hair, comprise the integumentary system. Abnormalities in the colour, shape and clinical appearance of nails can be indicative of pathophysiological disorders, habit-tics such as bitten nails, poor grooming, nutritional deficits and cosmetic practices. Discolouration and changes in nail appearance are common reasons for referral of individuals to dermatologists. This paper presents a mélange of common nail disorders with a clinical focus on those that present with discolouration.","PeriodicalId":44572,"journal":{"name":"Wound Practice and Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49059996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
There are dramatic disparities in the life expectancy, health and healthcare access between Indigenous and non-Indigenous Australians. The burden of chronic disease is significantly
土著和非土著澳大利亚人在预期寿命、健康和医疗保健方面存在巨大差异。慢性病的负担很重
{"title":"Cutaneous infection and atopic dermatitis: the importance of early intervention in Indigenous children in Australia","authors":"R. Russell, D. Slape, I. McCrossin, J. Frew","doi":"10.33235/wpr.30.1.34-39","DOIUrl":"https://doi.org/10.33235/wpr.30.1.34-39","url":null,"abstract":"There are dramatic disparities in the life expectancy, health and healthcare access between Indigenous and non-Indigenous Australians. The burden of chronic disease is significantly","PeriodicalId":44572,"journal":{"name":"Wound Practice and Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41765015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pathergy: a review of potential mechanisms and novel therapeutic targets","authors":"A. Honigman, J. Kern, J. Frew","doi":"10.33235/wpr.30.1.55-61","DOIUrl":"https://doi.org/10.33235/wpr.30.1.55-61","url":null,"abstract":"healing","PeriodicalId":44572,"journal":{"name":"Wound Practice and Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48697966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hidradenitis suppurativa: an up-to-date review of clinical features, pathogenesis and therapeutic approaches","authors":"A. Moussa, Anneliese Willems, Rodney D Sinclair","doi":"10.33235/wpr.30.1.40-49","DOIUrl":"https://doi.org/10.33235/wpr.30.1.40-49","url":null,"abstract":"","PeriodicalId":44572,"journal":{"name":"Wound Practice and Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44477181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
New paradigms and advances in medical and translational science are often found at the boundaries of knowledge where multiple disciplines overlap. The ability to examine an issue or problem from a novel perspective may lead to insights and solutions not previously considered. Inflammation, both its mechanism and treatment, is a core tenet of wound research and is also central to a variety of dermatological conditions which are often encountered in the wound care setting.
{"title":"Dermatology and wound research: targeting inflammation through cooperation and collaboration","authors":"J. Frew","doi":"10.33235/wpr.30.1.5","DOIUrl":"https://doi.org/10.33235/wpr.30.1.5","url":null,"abstract":"New paradigms and advances in medical and translational science are often found at the boundaries of knowledge where multiple disciplines overlap. The ability to examine an issue or problem from a novel perspective may lead to insights and solutions not previously considered. Inflammation, both its mechanism and treatment, is a core tenet of wound research and is also central to a variety of dermatological conditions which are often encountered in the wound care setting.","PeriodicalId":44572,"journal":{"name":"Wound Practice and Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44356732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pyoderma gangrenosum: a review of the clinical, mechanistic and therapeutic landscape","authors":"A. Flora, J. Frew","doi":"10.33235/wpr.30.1.16-23","DOIUrl":"https://doi.org/10.33235/wpr.30.1.16-23","url":null,"abstract":".","PeriodicalId":44572,"journal":{"name":"Wound Practice and Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46490124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alopecia areata (AA) is a T cell-mediated autoimmune disease that has an estimated lifetime prevalence of 2.1%. Although clinically heterogenous, the typical presentation is of discrete, well-demarcated patches of non-scarring hair loss. In severe AA, complete loss of scalp hair (alopecia totalis, AT) or all hair (alopecia universalis, AU) may occur. There is considerable variation in how AA is treated by dermatologists. Recent insights into the aetiopathogenesis of AA have led to the emergence of several novel treatment strategies, including Janus kinase inhibitors and biologics. This review provides a contemporary evidence-based summary of AA, including clinical features, severity assessment, disease pathogenesis and current and emerging treatment strategies
{"title":"Alopecia areata: a review of diagnosis, pathogenesis and the therapeutic landscape","authors":"A. Moussa, L. Bokhari, Rodney D Sinclair","doi":"10.33235/wpr.30.1.24-33","DOIUrl":"https://doi.org/10.33235/wpr.30.1.24-33","url":null,"abstract":"Alopecia areata (AA) is a T cell-mediated autoimmune disease that has an estimated lifetime prevalence of 2.1%. Although clinically heterogenous, the typical presentation is of discrete, well-demarcated patches of non-scarring hair loss. In severe AA, complete loss of scalp hair (alopecia totalis, AT) or all hair (alopecia universalis, AU) may occur. There is considerable variation in how AA is treated by dermatologists. Recent insights into the aetiopathogenesis of AA have led to the emergence of several novel treatment strategies, including Janus kinase inhibitors and biologics. This review provides a contemporary evidence-based summary of AA, including clinical features, severity assessment, disease pathogenesis and current and emerging treatment strategies","PeriodicalId":44572,"journal":{"name":"Wound Practice and Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48844176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Necrobiosis lipoidica: a review of management and the role of compression","authors":"Dan-Qi Zhang, Gabrielle M McMullin","doi":"10.33235/wpr.30.1.11-15","DOIUrl":"https://doi.org/10.33235/wpr.30.1.11-15","url":null,"abstract":"lipoidica: a review","PeriodicalId":44572,"journal":{"name":"Wound Practice and Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44145178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-01DOI: 10.33235/wpr.29.4.230-233
U. Bui, Savannah M Aitcheson, S. Boxall, Tony W. Parker, Fiona M. Wood, Rachael Murray, K. Finlayson, A. Cowin
{"title":"Research priorities for fundamental wound research in Australia: a scoping review protocol","authors":"U. Bui, Savannah M Aitcheson, S. Boxall, Tony W. Parker, Fiona M. Wood, Rachael Murray, K. Finlayson, A. Cowin","doi":"10.33235/wpr.29.4.230-233","DOIUrl":"https://doi.org/10.33235/wpr.29.4.230-233","url":null,"abstract":"","PeriodicalId":44572,"journal":{"name":"Wound Practice and Research","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47756279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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