Pub Date : 2022-12-03DOI: 10.52101/9785870190921_2021_8_268
Владимир Александрович Куркин, Елена Николаевна Зайцева, Анна Владимировна Куркина, Анна Евгеньевна Савельева, Анастасия Игоревна Климова, Анастасия Сергеевна Цибина
Бархатцы отклонённые (Tagetes patula L.) являются ценным источником биологически активных соединений, в том числе флавоноидов. Целью настоящего исследования явилось изучение диуретической активности густого экстракта из цветков бархатцев отклонённых, а также доминирующих флавоноидов данного вида сырья — патулитрина и патулетина. С использованием колоночной хроматографии на силикагеле L 40/100 выделено два флавоноидных вещества — патулетин (3,5,7,3’,4’-пентагидрокси-6-метоксифлавон) и патулитрин (7-О-β-D-глюкопиранозид 3,5,7,3’,4’-пентагидрокси-6-метоксифлавона), идентификацию которых проводили с помощью УФ-, 1Н и 13С ЯМР-спектроскопии. При однократном внутрижелудочном введении густого экстракта цветков бархатцев в дозе 10 мг/кг, патулетина и патулитрина в дозе 1 мг/кг на фоне 3 % водной нагрузки в 4-часовом эксперименте у животных опытной группы относительно показателей водного контроля достоверно возрастал диурез (аналогично действию препарата сравнения фуросемида в пороговой дозе 1 мг/кг); к концу 24-часового эксперимента с густым экстрактом отмечалось достоверное увеличение диуреза (аналогичное действию гипотиазида в эффективной средней терапевтической дозе 20 мг/кг), а также креатининуреза (свидетельствующее о возрастании клубочковой фильтрации).
{"title":"ИЗУЧЕНИЕ ФЛАВОНОИДОВ ЦВЕТКОВ БАРХАТЦЕВ ОТКЛОНЕННЫХ","authors":"Владимир Александрович Куркин, Елена Николаевна Зайцева, Анна Владимировна Куркина, Анна Евгеньевна Савельева, Анастасия Игоревна Климова, Анастасия Сергеевна Цибина","doi":"10.52101/9785870190921_2021_8_268","DOIUrl":"https://doi.org/10.52101/9785870190921_2021_8_268","url":null,"abstract":"Бархатцы отклонённые (Tagetes patula L.) являются ценным источником биологически активных соединений, в том числе флавоноидов. Целью настоящего исследования явилось изучение диуретической активности густого экстракта из цветков бархатцев отклонённых, а также доминирующих флавоноидов данного вида сырья — патулитрина и патулетина. С использованием колоночной хроматографии на силикагеле L 40/100 выделено два флавоноидных вещества — патулетин (3,5,7,3’,4’-пентагидрокси-6-метоксифлавон) и патулитрин (7-О-β-D-глюкопиранозид 3,5,7,3’,4’-пентагидрокси-6-метоксифлавона), идентификацию которых проводили с помощью УФ-, 1Н и 13С ЯМР-спектроскопии. При однократном внутрижелудочном введении густого экстракта цветков бархатцев в дозе 10 мг/кг, патулетина и патулитрина в дозе 1 мг/кг на фоне 3 % водной нагрузки в 4-часовом эксперименте у животных опытной группы относительно показателей водного контроля достоверно возрастал диурез (аналогично действию препарата сравнения фуросемида в пороговой дозе 1 мг/кг); к концу 24-часового эксперимента с густым экстрактом отмечалось достоверное увеличение диуреза (аналогичное действию гипотиазида в эффективной средней терапевтической дозе 20 мг/кг), а также креатининуреза (свидетельствующее о возрастании клубочковой фильтрации).","PeriodicalId":448420,"journal":{"name":"Современные тенденции развития технологий здоровьесбережения. Сборник научных трудов Международной научной конференции","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133629583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.52101/9785870190921_2021_8_35
И. Ю. Селютина, М. Е. Дыйканова
In commodity farms, the technology of growing onions by sowing from seeds in an annual crop is spreading. However, the average yield of onions in Russia is at a low level: 20–30 t/ha. New varieties and hybrids should have early maturity, high yield, resistance to diseases and pests, and good keeping quality. In the State register of breeding achievements of the Russian Federation, approved for use in 2020, 385 varieties and hybrids of onions are registered, including 195 varieties and 190 hybrids. In 2020, eighteen new hybrids and one variety are included. Along with the creation of heterotic hybrids in the moment in the Department of breeding and seed production of the All-Russian Research Institute of Vegetable Growing – branch of Federal Scientifi c Centre of Vegetable Growing (ARRIVG – branch of FSBSI FSVC) also continues the selection of varieties that show high performance when grown in annual crops. The aim of the work is to evaluate promising samples of onions in a competitive nursery. The research was carried out in 2019–2020 in the Moscow region at ARRIVG – branch of FSBSI FSVC. Experiments were carried out according to generally accepted methods. Seeds were sown on April 24 with a precision seeding machine Gaspardo Olimpia on a ridge of 1.4 m according to a two-line three-row scheme, with a distance between the lines of 8 cm. The seeding rate is 0.8 million pieces/ ha of germinating seeds. The accounting area of the plot is 98 m 2 , the repetition of the experience options is three-fold. The lack of moisture during the growing season was compensated by irrigation through a drip irrigation system, maintaining the HB at the level of 80– 85%. The object of research is promising samples of onion Sn-20/16 and Al-20/16. As a standard, the Forward variety was used. The testing results showed that the varieties Sn-20/16 and Al-20/16 are promising for the Moscow region, as they have a high yield potential and high quality of bulbs.
{"title":"ВЛИЯНИЕ ГЛАУКОНИТОВОГО ПЕСКА НА ПРОДУКТИВНОСТЬ ЯРОВОГО ЧЕСНОКА В УСЛОВИЯХ МОСКОВСКОЙ ОБЛАСТИ","authors":"И. Ю. Селютина, М. Е. Дыйканова","doi":"10.52101/9785870190921_2021_8_35","DOIUrl":"https://doi.org/10.52101/9785870190921_2021_8_35","url":null,"abstract":"In commodity farms, the technology of growing onions by sowing from seeds in an annual crop is spreading. However, the average yield of onions in Russia is at a low level: 20–30 t/ha. New varieties and hybrids should have early maturity, high yield, resistance to diseases and pests, and good keeping quality. In the State register of breeding achievements of the Russian Federation, approved for use in 2020, 385 varieties and hybrids of onions are registered, including 195 varieties and 190 hybrids. In 2020, eighteen new hybrids and one variety are included. Along with the creation of heterotic hybrids in the moment in the Department of breeding and seed production of the All-Russian Research Institute of Vegetable Growing – branch of Federal Scientifi c Centre of Vegetable Growing (ARRIVG – branch of FSBSI FSVC) also continues the selection of varieties that show high performance when grown in annual crops. The aim of the work is to evaluate promising samples of onions in a competitive nursery. The research was carried out in 2019–2020 in the Moscow region at ARRIVG – branch of FSBSI FSVC. Experiments were carried out according to generally accepted methods. Seeds were sown on April 24 with a precision seeding machine Gaspardo Olimpia on a ridge of 1.4 m according to a two-line three-row scheme, with a distance between the lines of 8 cm. The seeding rate is 0.8 million pieces/ ha of germinating seeds. The accounting area of the plot is 98 m 2 , the repetition of the experience options is three-fold. The lack of moisture during the growing season was compensated by irrigation through a drip irrigation system, maintaining the HB at the level of 80– 85%. The object of research is promising samples of onion Sn-20/16 and Al-20/16. As a standard, the Forward variety was used. The testing results showed that the varieties Sn-20/16 and Al-20/16 are promising for the Moscow region, as they have a high yield potential and high quality of bulbs.","PeriodicalId":448420,"journal":{"name":"Современные тенденции развития технологий здоровьесбережения. Сборник научных трудов Международной научной конференции","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121978412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.52101/9785870190921_2021_8_14
И. В. Басалаева, М. Ю. Грязнов, Светлана Анатольевна Тоцкая
{"title":"БИОЛОГИЧЕСКИЕ ОСОБЕННОСТИ SCUTELLARIA BAICALENSIS GEORGI В УСЛОВИЯХ КУЛЬТУРЫ В НЕЧЕРНОЗЕМНОЙ ЗОНЕ РОССИИ","authors":"И. В. Басалаева, М. Ю. Грязнов, Светлана Анатольевна Тоцкая","doi":"10.52101/9785870190921_2021_8_14","DOIUrl":"https://doi.org/10.52101/9785870190921_2021_8_14","url":null,"abstract":"","PeriodicalId":448420,"journal":{"name":"Современные тенденции развития технологий здоровьесбережения. Сборник научных трудов Международной научной конференции","volume":"92 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126173919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.52101/9785870190921_2021_8_416
К. Е. Лукинова, В. Д. Бояршинов, Екатерина Вячеславовна Зорина
{"title":"ИЗУЧЕНИЕ АНТИРАДИКАЛЬНОЙ АКТИВНОСТИ НАСТОЕВ МАНЖЕТКИ МЯГКОЙ И МАНЖЕТКИ ОБЫКНОВЕННОЙ","authors":"К. Е. Лукинова, В. Д. Бояршинов, Екатерина Вячеславовна Зорина","doi":"10.52101/9785870190921_2021_8_416","DOIUrl":"https://doi.org/10.52101/9785870190921_2021_8_416","url":null,"abstract":"","PeriodicalId":448420,"journal":{"name":"Современные тенденции развития технологий здоровьесбережения. Сборник научных трудов Международной научной конференции","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129858606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.52101/9785870190921_2021_8_423
Е. Р. Гатиатулина, Д. С. Кабанов
{"title":"СРАВНИТЕЛЬНЫЙ АНАЛИЗ ПРОДУКЦИИ ФАКТОРА НЕКРОЗА ОПУХОЛИ В ОТВЕТ НА ЛИПОПОЛИСАХАРИДЫ ИЛИ ПЕНТАГАЛЛОИЛГЛЮКОЗУ IN VITRO И IN VIVO","authors":"Е. Р. Гатиатулина, Д. С. Кабанов","doi":"10.52101/9785870190921_2021_8_423","DOIUrl":"https://doi.org/10.52101/9785870190921_2021_8_423","url":null,"abstract":"","PeriodicalId":448420,"journal":{"name":"Современные тенденции развития технологий здоровьесбережения. Сборник научных трудов Международной научной конференции","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117218216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.52101/9785870190921_2021_8_379
K. Badekova, M. E. Zholdasbaev, G. Atazhanova, S. Akhmetova, M. Smagulov
{"title":"THE STUDY OF ANTIMICROBIAL AND ANTIFUNGAL ACTIVITY OF EXTRACTS ORIGANUM VULGARE L.","authors":"K. Badekova, M. E. Zholdasbaev, G. Atazhanova, S. Akhmetova, M. Smagulov","doi":"10.52101/9785870190921_2021_8_379","DOIUrl":"https://doi.org/10.52101/9785870190921_2021_8_379","url":null,"abstract":"","PeriodicalId":448420,"journal":{"name":"Современные тенденции развития технологий здоровьесбережения. Сборник научных трудов Международной научной конференции","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122632725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.52101/9785870190921_2021_8_404
С. В. Лемясева, М. В. Боровкова, О. С. Кузина
{"title":"ИЯНИЕ ЦИКОРИЯ ОБЫКНОВЕННОГО НА ПОКАЗАТЕЛИ КРОВИ И ГЕМОСТАЗ ЭКСПЕРИМЕНТАЛЬНЫХ ЖИВОТНЫХ ПРИ ОДНОКРАТНОМ И ДЛИТЕЛЬНОМ ВВЕДЕНИИ","authors":"С. В. Лемясева, М. В. Боровкова, О. С. Кузина","doi":"10.52101/9785870190921_2021_8_404","DOIUrl":"https://doi.org/10.52101/9785870190921_2021_8_404","url":null,"abstract":"","PeriodicalId":448420,"journal":{"name":"Современные тенденции развития технологий здоровьесбережения. Сборник научных трудов Международной научной конференции","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127531604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.52101/9785870190921_2021_8_344
А.С. Адекенова, А. И. Макубаева, А. А. Рахатаева, Х. Мамырхан
{"title":"ЛЕЧЕБНОЕ ЖИДКОЕ МЫЛО С ЭФИРНЫМ МАСЛОМ РОМАШКИ АПТЕЧНОЙ","authors":"А.С. Адекенова, А. И. Макубаева, А. А. Рахатаева, Х. Мамырхан","doi":"10.52101/9785870190921_2021_8_344","DOIUrl":"https://doi.org/10.52101/9785870190921_2021_8_344","url":null,"abstract":"","PeriodicalId":448420,"journal":{"name":"Современные тенденции развития технологий здоровьесбережения. Сборник научных трудов Международной научной конференции","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127365506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.52101/9785870190921_2021_8_322
В. И. Зверева, Ольга Александровна Семкина
Medicinal plant raw materials is a promising source for the development of drugs used for the prevention and treatment of thyroid dysfunction. It is interesting the study of the domestic pharmaceutical market in order to determine the proportion of drugs of plant origin, the above-mentioned pharmacological group. The results of this study indicate that among the drugs used for the prevention and treatment of diseases of the thyroid gland, drugs of plant origin do not exist; the largest proportion of the substances represented by the Russian manufacturers. At the same time, among the ready-to-use dosage forms, the form has an advantage, as a country of origin is Germany, which indicates the patient's dependence on supplies from abroad. The study also showed a lack of diversity of dosage forms of the studied group of drugs, which affects the adherence of patients to the treatment.
{"title":"РАЗРАБОТКА ЛЕКАРСТВЕННЫХ СРЕДСТВ ДЛЯ ПРОФИЛАКТИКИ И ЛЕЧЕНИЯ ЗАБОЛЕВАНИЙ ЩИТОВИДНОЙ ЖЕЛЕЗЫ","authors":"В. И. Зверева, Ольга Александровна Семкина","doi":"10.52101/9785870190921_2021_8_322","DOIUrl":"https://doi.org/10.52101/9785870190921_2021_8_322","url":null,"abstract":"Medicinal plant raw materials is a promising source for the development of drugs used for the prevention and treatment of thyroid dysfunction. It is interesting the study of the domestic pharmaceutical market in order to determine the proportion of drugs of plant origin, the above-mentioned pharmacological group. The results of this study indicate that among the drugs used for the prevention and treatment of diseases of the thyroid gland, drugs of plant origin do not exist; the largest proportion of the substances represented by the Russian manufacturers. At the same time, among the ready-to-use dosage forms, the form has an advantage, as a country of origin is Germany, which indicates the patient's dependence on supplies from abroad. The study also showed a lack of diversity of dosage forms of the studied group of drugs, which affects the adherence of patients to the treatment.","PeriodicalId":448420,"journal":{"name":"Современные тенденции развития технологий здоровьесбережения. Сборник научных трудов Международной научной конференции","volume":"115 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132396522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.52101/9785870190921_2021_8_23
Айна Шугаевна Амиржанова, Г. Т. Модин, А. К. Абдикадир, М. Ю. Ишмуратова, Р. М. Абдуллабекова
{"title":"ТЕХНОЛОГИЯ ЗАГОТОВКИ РАСТИТЕЛЬНОГО СЫРЬЯ SPIRAEA HYPERICIFOLIA","authors":"Айна Шугаевна Амиржанова, Г. Т. Модин, А. К. Абдикадир, М. Ю. Ишмуратова, Р. М. Абдуллабекова","doi":"10.52101/9785870190921_2021_8_23","DOIUrl":"https://doi.org/10.52101/9785870190921_2021_8_23","url":null,"abstract":"","PeriodicalId":448420,"journal":{"name":"Современные тенденции развития технологий здоровьесбережения. Сборник научных трудов Международной научной конференции","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131641711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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