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The efficacy of vitamin D supplementation for irritable bowel syndrome: a systematic review with meta-analysis. 维生素 D 补充剂对肠易激综合征的疗效:系统回顾与荟萃分析。
IF 4.4 Q3 TELECOMMUNICATIONS Pub Date : 2022-05-05 DOI: 10.1186/s12937-022-00777-x
Hangkai Huang, Linjie Lu, Yishu Chen, Yan Zeng, Chengfu Xu

Background: Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder involving gut-brain interactions with limited effective treatment options. Vitamin D deficiency is commonly observed in patients with IBS, but whether vitamin D supplementation ameliorates IBS is controversial in randomized controlled trials. The present systematic review and meta-analysis explored the efficacy of vitamin D supplementation in patients with IBS.

Methods: We performed a systematic search of potentially relevant publications from PubMed, EMBASE, the Cochrane Central Register of Controlled Studies and the Web of Science up until January 2022. We assessed the weighted mean difference (WMD) and 95% confidence interval (95% CI) of the IBS severity scoring system (IBS-SSS), IBS quality of life (IBS-QoL) and IBS total score (IBS-TS) before and after vitamin D supplementation intervention.

Results: We included four randomized, placebo-controlled trials involving 335 participants. The differences in IBS-SSS score between participants in the intervention group and the placebo group increased after intervention (WMD: -55.55, 95% CI: -70.22 to -40.87, I2 = 53.7%, after intervention; WMD: -3.17, 95% CI: -18.15 to 11.81, I2 = 0.0%, before intervention). Participants receiving vitamin D supplementation showed greater improvement in IBS-SSS after intervention than participants receiving placebo treatment (WMD: -84.21, 95% CI: -111.38 to -57.05, I2 = 73.2%; WMD: -28.29, 95% CI: -49.95 to -6.62, I2 = 46.6%, respectively). Vitamin D supplementation was also superior to placebo in IBS-QoL improvement (WMD: 14.98, 95% CI: 12.06 to 17.90, I2 = 0.0%; WMD: 6.55, 95% CI: -2.23 to 15.33, I2 = 82.7%, respectively). Sensitivity analyses revealed an unstable pooled effect on IBS-TS in participants receiving vitamin D supplementation. Therefore, we did not evaluate the efficacy of vitamin D intervention in IBS-TS.

Conclusions: This systematic review and meta-analysis suggested that vitamin D supplementation was superior to placebo for IBS treatment.

背景:肠易激综合征(IBS)是一种涉及肠道与大脑相互作用的慢性胃肠道疾病,有效的治疗方案有限。肠易激综合征患者普遍缺乏维生素 D,但在随机对照试验中,维生素 D 补充剂是否能改善肠易激综合征尚存争议。本系统综述和荟萃分析探讨了补充维生素 D 对肠易激综合征患者的疗效:我们对截至 2022 年 1 月的 PubMed、EMBASE、Cochrane Central Register of Controlled Studies 和 Web of Science 中可能相关的出版物进行了系统检索。我们评估了维生素D补充剂干预前后肠易激综合征严重程度评分系统(IBS-SSS)、肠易激综合征生活质量(IBS-QoL)和肠易激综合征总分(IBS-TS)的加权平均差(WMD)和95%置信区间(95% CI):结果:我们纳入了四项随机安慰剂对照试验,共有 335 人参与。干预后,干预组与安慰剂组参与者的 IBS-SSS 得分差异增大(干预后,WMD:-55.55,95% CI:-70.22 至 -40.87,I2 = 53.7%;干预前,WMD:-3.17,95% CI:-18.15 至 11.81,I2 = 0.0%)。与接受安慰剂治疗的参与者相比,接受维生素 D 补充剂治疗的参与者在干预后的 IBS-SSS 改善程度更大(WMD:-84.21,95% CI:-111.38 至 -57.05,I2 = 73.2%;WMD:-28.29,95% CI:-49.95 至 -6.62,I2 = 46.6%)。维生素 D 补充剂在改善肠易激综合征生活质量方面也优于安慰剂(WMD:14.98,95% CI:12.06 至 17.90,I2 = 0.0%;WMD:6.55,95% CI:-2.23 至 15.33,I2 = 82.7%)。敏感性分析显示,在接受维生素 D 补充剂的参与者中,IBS-TS 的集合效应并不稳定。因此,我们没有评估维生素D干预对IBS-TS的疗效:本系统综述和荟萃分析表明,在治疗肠易激综合征方面,补充维生素 D 优于安慰剂。
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引用次数: 0
Artificial Intelligence Feedback Loops in Mobile Platform Business Models 移动平台商业模式中的人工智能反馈回路
IF 2.5 Q3 TELECOMMUNICATIONS Pub Date : 2022-04-19 DOI: 10.1007/s10776-022-00556-9
E. Katsamakas, O. Pavlov
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引用次数: 3
An Intelligent Probabilistic Whale Optimization Algorithm (i-WOA) for Clustering in Vehicular Ad Hoc Networks 一种用于车载Ad Hoc网络聚类的智能概率鲸鱼优化算法(i-WOA)
IF 2.5 Q3 TELECOMMUNICATIONS Pub Date : 2022-03-29 DOI: 10.1007/s10776-022-00555-w
Ghassan Husnain, Shahzad Anwar
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引用次数: 15
Terahertz Dielectric Characterization of Low-Loss Thermoplastics for 6G Applications 用于6G应用的低损耗热塑性塑料的太赫兹介电特性
IF 2.5 Q3 TELECOMMUNICATIONS Pub Date : 2022-03-12 DOI: 10.1007/s10776-022-00554-x
Min Zhai, A. Locquet, D. Citrin
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引用次数: 5
An Empirical Study on the Causes of Mobile Phone Dependence of College Students 大学生手机依赖原因的实证研究
IF 2.5 Q3 TELECOMMUNICATIONS Pub Date : 2022-03-09 DOI: 10.1007/s10776-021-00532-9
Linghui Tian, Xiaolu Zhou
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引用次数: 1
Mobility Aware Adaptive Hybrid MAC Protocol for WSN 基于移动感知的WSN自适应混合MAC协议
IF 2.5 Q3 TELECOMMUNICATIONS Pub Date : 2022-02-23 DOI: 10.1007/s10776-022-00553-y
M. Rajesh, B. L. Raju, B. Bhandari
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引用次数: 2
Relay-Assisted Wireless Energy Transfer for Efficient Spectrum Sharing in Harsh Environments 恶劣环境下实现高效频谱共享的中继辅助无线能量传输
IF 2.5 Q3 TELECOMMUNICATIONS Pub Date : 2022-01-29 DOI: 10.1007/s10776-022-00552-z
Sonia Naderi, Somayeh Khosroazad, A. Abedi
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引用次数: 2
Machine Learning Protocol for Secure 5G Handovers 用于安全5G切换的机器学习协议
IF 2.5 Q3 TELECOMMUNICATIONS Pub Date : 2022-01-27 DOI: 10.1007/s10776-021-00547-2
V. O. Nyangaresi, A. Rodrigues, Silvance O. Abeka
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引用次数: 10
Performance Analysis of a Decode-and-forward based Mixed RF-FSO-VLC System 一种基于解码和前向的混合RF-FSO-VLC系统的性能分析
IF 2.5 Q3 TELECOMMUNICATIONS Pub Date : 2022-01-25 DOI: 10.21203/rs.3.rs-1288723/v1
Rima Deka, Sanya Anees
In this paper, the performance analysis of a cooperative radio frequency-free space optical communication-visible-light-communication (RF- FSO - VLC ) system using decode-and-forward ( DF ) relays is presented. In the proposed model, the RF link acts as the core network, the FSO link is used for providing last mile connectivity for the indoor cell users communicating through VLC environment. The RF link is characterized by Nakagami - $m$ -distributed fading, while the FSO link undergoes Double Generalized Gamma ( DGG ) distributed atmospheric turbulence and pointing errors and the VLC link is characterized by the Lambertian pattern of the LED. The closed-form expressions of the statistical characteristics of signal-to-noise-ratio ( SNR ) of the DF based triple-hop system are evaluated using which various performance metrics, i.e, outage probability, bit error rate ( BER ), and capacity of the considered system are obtained. The numerical results show that the system's performance gets severely affected by the RF fading, atmospheric turbulence, and pointing errors. The outage performance of the system decreases as field-of-view ( FOV ) and the height of the light-emitting-diode (LED) increase. It is also seen from the results that the BER performance of the system is better in case of heterodyne detection as compared to direct-detection. It is also observed that the capacity of the system decreases when the effect of atmospheric turbulence and pointing error is high and it increases when the no. of LEDs increases.
本文介绍了一种使用解码转发(DF)中继的协作射频自由空间光通信可见光通信(RF-FSO-VLC)系统的性能分析。在所提出的模型中,RF链路充当核心网络,FSO链路用于为通过VLC环境通信的室内小区用户提供最后一英里连接。RF链路的特征是Nakagami-$m$-分布式衰落,而FSO链路经历双广义伽马(DGG)分布式大气湍流和指向误差,VLC链路的特征在于LED的朗伯模式。评估了基于DF的三跳系统的信噪比(SNR)统计特性的闭合表达式,使用该表达式可以获得所考虑系统的各种性能指标,即中断概率、误码率(BER)和容量。数值结果表明,系统的性能受到射频衰落、大气湍流和指向误差的严重影响。系统的断电性能随着视场(FOV)和发光二极管(LED)高度的增加而降低。从结果中还可以看出,与直接检测相比,在外差检测的情况下,该系统的BER性能更好。还观察到,当大气湍流和指向误差的影响高时,系统的容量降低,而当LED的数量增加时,系统的能力增加。
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引用次数: 0
An Adaptive Transmission Mode Selection Scheme for Cellular Underlaid D2D Communication 蜂窝底层D2D通信的自适应传输模式选择方案
IF 2.5 Q3 TELECOMMUNICATIONS Pub Date : 2022-01-22 DOI: 10.1007/s10776-022-00550-1
N. Sharma, Shailesh Khanolkar, S. Kumar, A. Anpalagan
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引用次数: 0
期刊
International Journal of Wireless Information Networks
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