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Evaluation of the efficacy of pulsed radiofrequency therapy in patients with lumbosacral radicular pain: An analysis of single-center data. 评估脉冲射频疗法对腰骶部根性疼痛患者的疗效:单中心数据分析。
IF 0.6 Q3 Medicine Pub Date : 2024-01-01 DOI: 10.14744/agri.2022.60234
Gökhan Yıldız, Şeref Çelik, Erkan Yavuz Akçaboy, Şaziye Şahin, Samet Sancar Kaya, Müge Baran, Hamit Göksu

Objectives: Lumbosacral radicular pain (LRP) is one of the most common causes of neuropathic pain. This pain often arises from inflammation in the dorsal root ganglia (DRG) or spinal nerves. Despite various treatment modalities, success rates are not very high in chronic LRP cases. Pulsed radiofrequency (PRF) therapy, frequently applied to the DRG, is widely used, but its effectiveness is often questioned in various studies. The primary aim of our study is to evaluate the effectiveness of PRF treatment in 154 patients.

Methods: Patients with LRP for longer than 3 months, treated with PRF, were included in this study. To assess the efficacy of PRF treatment, numerical rating scale (NRS) scores were evaluated at the 4th-week and 6th-month follow-ups.

Results: The NRS scores were significantly lower at the 4th-week and 6th-month follow-ups compared to pre-treatment levels (p<0.001). However, there was no significant difference between the mean NRS scores at the 4th week and 6th month.

Conclusion: Success in interventional pain procedures is often considered as at least a 50% reduction in pain scores. The success rate for PRF treatment for LRP in the literature varies between 30% and 60%, which is similar to our findings at the 4th week and 6th month. PRF treatment is widely used due to its low side-effect profile and cost-effectiveness in the long term. There is no fully standardized practice regarding procedural aspects, such as the duration of the application, and prospective studies with larger participation are needed.

目的:腰骶部根性疼痛(LRP)是神经性疼痛最常见的原因之一。这种疼痛通常源于背根神经节(DRG)或脊神经的炎症。尽管治疗方法多种多样,但慢性 LRP 病例的成功率并不高。脉冲射频(PRF)疗法经常应用于背根神经节,被广泛使用,但其有效性经常在各种研究中受到质疑。我们研究的主要目的是评估 154 例患者接受脉冲射频治疗的效果:本研究纳入了接受 PRF 治疗超过 3 个月的 LRP 患者。为了评估 PRF 治疗的疗效,我们在第 4 周和第 6 个月的随访中对数字评分量表(NRS)评分进行了评估:结果:第四周和第 6 个月随访时的 NRS 评分明显低于治疗前的水平(p):介入性疼痛治疗的成功通常被认为是疼痛评分至少降低 50%。文献中 PRF 治疗 LRP 的成功率在 30% 到 60% 之间,这与我们在第 4 周和第 6 个月的研究结果相似。PRF 治疗因其副作用小、长期成本效益高而被广泛使用。在程序方面,如应用时间的长短,目前还没有完全标准化的做法,因此需要更多参与的前瞻性研究。
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引用次数: 0
Percutaneous fluoroscopic lumbar facet joint synovial cyst aspiration for manifesting with radiculopathy and low back pain. 经皮透视腰椎面关节滑膜囊肿抽吸术治疗表现为根性病变和腰痛的腰椎面关节滑膜囊肿。
IF 0.8 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-01-01 DOI: 10.14744/agri.2022.07742
Kamer Dere

Lumbar facet joint synovial cysts are benign degenerative abnormalities of the lumbar spine and can cause lower extremity ra-diculopathy, spinal stenosis, and low back pain. Herein, we report a case with a synovial cyst treated by percutaneous fluoros-copic aspiration via the facet joint. A 46-year-old woman presented to the neurosurgery clinic complaining of a 2-month history of low back pain with left-sided radicular symptoms. Her physical examination was consistent with a left L5 radiculopathy, and MRI confirmed a left L5-S1 facet joint synovial cyst compressing the nerve root. Percutaneous fluoroscopic cyst aspiration via the facet joint was planned. The cyst was aspirated, and a total of 0.2-0.3 cc of fluid was removed. During the aspiration, the patient reported pain relief. Thus, the procedure was completed. An MRI taken after 3 weeks showed that the cyst had become smaller than before, with no evidence of nerve root compression. For 1 year, the patient has had no pain or neurological symptoms. Patients who undergo a fluoroscopic percutaneous rupture by filling of the facet joint cyst typically have successful outcomes. We conclude that aspiration of the facet joint cyst without rupture can also result in the same successful outcome.

腰椎面关节滑膜囊肿是腰椎的良性退行性畸形,可导致下肢二叉病、椎管狭窄和腰痛。在此,我们报告了一例经皮氟镜经关节抽吸治疗滑膜囊肿的病例。一名 46 岁的女性来到神经外科门诊,主诉其腰痛病史长达 2 个月,并伴有左侧根性症状。她的体格检查结果与左侧 L5 根性病变一致,核磁共振成像证实左侧 L5-S1 椎面关节滑膜囊肿压迫神经根。计划通过经皮透视关节囊肿抽吸术。对囊肿进行了抽吸,共抽出0.2-0.3毫升液体。在抽吸过程中,患者表示疼痛有所缓解。手术就此结束。3 周后进行的核磁共振成像显示,囊肿比之前变小了,没有压迫神经根的迹象。一年来,患者一直没有疼痛或神经症状。接受透视经皮破裂填充面关节囊肿手术的患者通常都能获得成功。我们的结论是,在不破裂的情况下抽吸面关节囊肿也能获得同样的成功结果。
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引用次数: 0
The effectiveness of high dose steroid in post-corona severe headache. 大剂量类固醇治疗电晕后严重头痛的疗效。
IF 0.6 Q3 Medicine Pub Date : 2023-10-01 DOI: 10.14744/agri.2022.33410
TepeNermin, TertemizOktay Faysal
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引用次数: 0
The effect of erector spinae plane block on the use of anesthetic medications in lumbar spine surgery. 竖脊肌平面阻滞对腰椎手术麻醉药物使用的影响。
IF 0.6 Q3 Medicine Pub Date : 2023-10-01 DOI: 10.14744/agri.2022.48992
NashibiMasoud, SezariParisa, SafariFarhad, TeymourianHouman, AsgariSogol, MottaghiKamran

Objectives: To reduce the drug side effects and facilitate the emergence from anesthesia after complex spine surgery, various methods have been proposed. One of these methods is ESPB, which has been less studied. Hence, we conducted this study to evaluate the effectiveness of ESPB on the use of anesthetic drugs in lumbar spine surgery.

Methods: In this study, 70 patients undergoing lumbar spine fusion surgery were studied. Patients were randomly divided into two groups: the case group (n=35), in which bilateral ESPB was done, and the control group (n=35). After standard anesthesia protocols, anesthesia was maintained with isoflurane in both groups. Intraoperative isoflurane and perioperative opioid consumption were recorded. Statistical analysis was performed using SPSS software version 21.

Results: Intraoperative use of fentanyl in the case group was significantly lower than the control group (14.29±21.5 vs. 65.96±73.33 µg, p<0.001). Furthermore, isoflurane consumption in the intervention group compared to the controls was significantly lower (20.71±5.02 versus 28.83±8.68 mL, p<0.001). Moreover, the emergence time was significantly shorter in the case group than in the control group (8.49±4.30 minutes versus 15.00±4.94, p<0.001). In the post-anesthesia care unit 1 h after surgery, the pain scores in the case group were significantly lower than the controls (p<0.001).

Conclusion: ESPB under ultrasound guidance is an effective method of regional anesthesia/analgesia for lumbar spine surgery (fusion) by decreasing the consumption of anesthetics during and following the surgery.

目的:为了减少复杂脊柱手术后的药物副作用,促进麻醉苏醒,人们提出了各种方法。其中一种方法是ESPB,研究较少。因此,我们进行了这项研究,以评估ESPB在腰椎手术中麻醉药物使用的有效性。方法:对70例接受腰椎融合术的患者进行研究。患者被随机分为两组:病例组(n=35)和对照组(n=35%),其中进行双侧ESPB。在标准麻醉方案后,两组均使用异氟烷维持麻醉。记录术中异氟醚和围手术期阿片类药物的消耗情况。结果:病例组术中芬太尼的使用量显著低于对照组(14.29±21.5 vs.65.96±73.33µg,P结论:超声引导下的ESPB是一种有效的腰椎手术(融合)区域麻醉/镇痛方法,可减少术中和术中麻醉剂的消耗手术后。
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引用次数: 0
The investigation of antidepressant and anxiolytic effects of pregabalin and its mechanisms of action in rats 普瑞巴林抗抑郁、抗焦虑作用及其作用机制的研究
IF 0.6 Q3 Medicine Pub Date : 2023-10-01 DOI: 10.14744/agri.2022.98474
S. Aydin
OBJECTIVES Pregabalin (PGB) is used in drug-resistant epilepsy. Also, it has analgesic effects in painful syndromes. Depression and anxiety are commonly seen in epilepsy and neuropathic pain patients. PGB is often combined with anxiolytics and antidepressants. We aimed to investigate the antidepressant and anxiolytic effects of PGB and compare its effects with those of antidepressant and anxiolytic drugs and their combined use. METHODS Wistar Albino rats were used, and PGB (5, 10, 20, and 40 mg/kg), amitriptylin (AMT), fluoxetine (FLX), ketamine (KET), and diazepam (DZM), as well as combinations of PGB (20 mg/kg) with AMT, FLX, KET, and DZM, were administered. Elevated plus maze, forced swimming, and locomotor activity tests were performed. RESULTS In the elevated plus maze, PGB10, 20, 40, AMT, FLX, and DZM increased open arm time. The PGB20+FLX combination increased compared to PGB20. In forced swimming, PGB doses increased immobility time. AMT, FLX, DZM, and KET decreased compared to control and PGB doses. Other combinations of PGB20 reversed immobility time, except FLX. In locomotor activity, PGB20, AMT, KET, and DZM decreased distance. CONCLUSION PGB had a depressant effect in all doses and a dose-dependently anxiolytic effect. In combinations of PGB with AMT, KET, and DZM, it reversed their antidepressant effects. We assumed FLX could be preferred instead of AMT in patients using PGB. When PGB is used in combination, drug interactions should be considered. These results are also very remarkable in terms of pharmacoeconomics.
{"title":"The investigation of antidepressant and anxiolytic effects of pregabalin and its mechanisms of action in rats","authors":"S. Aydin","doi":"10.14744/agri.2022.98474","DOIUrl":"https://doi.org/10.14744/agri.2022.98474","url":null,"abstract":"OBJECTIVES Pregabalin (PGB) is used in drug-resistant epilepsy. Also, it has analgesic effects in painful syndromes. Depression and anxiety are commonly seen in epilepsy and neuropathic pain patients. PGB is often combined with anxiolytics and antidepressants. We aimed to investigate the antidepressant and anxiolytic effects of PGB and compare its effects with those of antidepressant and anxiolytic drugs and their combined use. METHODS Wistar Albino rats were used, and PGB (5, 10, 20, and 40 mg/kg), amitriptylin (AMT), fluoxetine (FLX), ketamine (KET), and diazepam (DZM), as well as combinations of PGB (20 mg/kg) with AMT, FLX, KET, and DZM, were administered. Elevated plus maze, forced swimming, and locomotor activity tests were performed. RESULTS In the elevated plus maze, PGB10, 20, 40, AMT, FLX, and DZM increased open arm time. The PGB20+FLX combination increased compared to PGB20. In forced swimming, PGB doses increased immobility time. AMT, FLX, DZM, and KET decreased compared to control and PGB doses. Other combinations of PGB20 reversed immobility time, except FLX. In locomotor activity, PGB20, AMT, KET, and DZM decreased distance. CONCLUSION PGB had a depressant effect in all doses and a dose-dependently anxiolytic effect. In combinations of PGB with AMT, KET, and DZM, it reversed their antidepressant effects. We assumed FLX could be preferred instead of AMT in patients using PGB. When PGB is used in combination, drug interactions should be considered. These results are also very remarkable in terms of pharmacoeconomics.","PeriodicalId":45603,"journal":{"name":"Agri-The Journal of the Turkish Society of Algology","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67313294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effectiveness of the erector spinae plane block using methylprednisolone and bupivacaine in post-herpetic neuralgia: Case series. 甲基强的松龙和布比卡因应用竖脊肌平面阻滞治疗疱疹后神经痛的疗效:病例系列。
IF 0.6 Q3 Medicine Pub Date : 2023-10-01 DOI: 10.14744/agri.2021.43926
PeksözUğur, ÖnerÜmran, ÇelikMine

Post-herpetic neuralgia (PHN) is the most common chronic complication of herpes zoster and the most common pain syndrome associated with infections. There are medical and interventional treatment options in PHN, and some patients may be resistant to the preferred medical treatments. This situation negatively affects the quality of life of the patient. Interventional treatments come to the fore, especially in patients in whom medical treatments are not sufficient, and systemic side effects such as hepatotoxicity and nephrotoxicity occur. Erector spinal plane block (ESPB) is a recently described ultrasound-guided regional anesthesia technique. It is especially used to prevent post-operative pain due to trunk surgeries. In this study, ESPB was administered with methylprednisolone and bupivacaine in five patients who developed PHN after thoracic herpes zoster and did not have an expected response to three-month medical treatments. Pain severity was assessed using the Numerical Pain Rating Scale. We want to emphasize that ESPB, which is applied with steroids and anesthetics, is a speedy and longacting treatment option that increases the quality of life of the patient, has low side effects, and is a cost-effective treatment option.

带状疱疹后神经痛(PHN)是带状疱疹最常见的慢性并发症,也是与感染相关的最常见的疼痛综合征。PHN有医学和介入治疗的选择,一些患者可能对首选的医学治疗有抵抗力。这种情况会对患者的生活质量产生负面影响。介入治疗脱颖而出,尤其是在药物治疗不足的患者中,会出现肝毒性和肾毒性等全身副作用。勃起脊髓平面阻滞(ESPB)是最近描述的一种超声引导的区域麻醉技术。它特别用于预防躯干手术引起的术后疼痛。在这项研究中,五名胸部带状疱疹后出现PHN的患者接受了甲基强的松龙和布比卡因的ESPB治疗,并且对三个月的药物治疗没有预期的反应。使用数字疼痛评定量表评估疼痛严重程度。我们想强调的是,ESPB与类固醇和麻醉剂一起使用,是一种快速、长效的治疗选择,可以提高患者的生活质量,副作用低,是一个具有成本效益的治疗选择。
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引用次数: 0
Effect of physical activity level on pain, functionality, and quality of life in migraine patients. 身体活动水平对偏头痛患者疼痛、功能和生活质量的影响。
IF 0.6 Q3 Medicine Pub Date : 2023-10-01 DOI: 10.14744/agri.2022.26504
Sağlı DirenGamze, Kaya CiddiPınar, ErgezenGizem, ŞahinMustafa

Objectives: This study aimed to determine the physical activity (PA) level of individuals with migraine and examine its effects on pain intensity (PI), disability, and quality of life (QoL).

Methods: Individuals diagnosed with migraine between the ages of 18 and 55 were included in the study. PA levels are assessed by the International PA Questionnaire Short Form (IPAQ-SF), PI with the McGill Melzack Pain Questionnaire, disability with the Migraine Disability Assessment Scale (MIDAS), and QoL with the World Health Organization QoL Scale Short Form (WHOQOL-BREF).

Results: A total of 88 individuals, with a mean age of 34.11±10.51 years, were included in the study; 53.41% were low active (LA), 30.68% were moderate active (MA), and 15.91% were high active (HA). The physical health of LAs (p=0.047) was lower than that of MAs. General (p<0.001), physical (p<0.001), and psychological (p=0.003) health scores were lower than HAs. LAs had a higher disability (p=0.042) and PI (p=0.001) than HAs. There was a weak negative correlation between PA and PI (p=0.001) and disability (p=0.005), and a weak positive correlation between PA levels and social (p=0.007) and environmental (p=0.013) scores, and moderate positive correlations with physical (p=0.000), general (p=0.000), and psychological (p=0.000) scores.

Conclusion: It was observed that as PA levels increased, PI decreased, and functionality and QoL increased in patients with migraine. Ensuring exercise continuity seems to be effective for improving the negative effects of migraine.

目的:本研究旨在确定偏头痛患者的体力活动水平,并检查其对疼痛强度(PI)、残疾和生活质量(QoL)的影响。方法:将18岁至55岁之间被诊断为偏头痛的患者纳入研究。PA水平采用国际PA问卷简表(IPAQ-SF)、PI采用麦吉尔-梅尔扎克疼痛问卷、残疾采用偏头痛残疾评估量表(MIDAS)和生活质量采用世界卫生组织生活质量量表简表(WHOQOL-BREF)进行评估;53.41%为低活性(LA),30.68%为中等活性(MA),15.91%为高活性(HA)。LA的身体健康状况(p=0.047)低于MA。概述(P结论:观察到偏头痛患者随着PA水平的升高,PI降低,功能和生活质量增加。确保运动的连续性似乎对改善偏头痛的负面影响有效。
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引用次数: 0
[Pain beliefs of cancer patients and associated factors]. [癌症患者的疼痛信念和相关因素]。
IF 0.6 Q3 Medicine Pub Date : 2023-10-01 DOI: 10.14744/agri.2022.55798
ÖzdemirÜlkü, Tokaç AkdenizAysel

Objectives: The aim is to determine the pain beliefs and related factors of cancer patients.

Methods: The study was designed as a descriptive and analytical type. It was completed between January and June 2019 with 100 individuals who were 18 years of age or older, who were receiving chemotherapy, and who agreed to participate in the study. Data were collected using a patient information form, a pain assessment form, and the Pain Beliefs Scale.

Results: In the results of the regression analysis, the psychological belief scores of those who acted nervously were statistically 0.408 points higher than those who acted calmly. Organic beliefs scores were statistically 0.814 points and 0.599 points higher in basically literate and primary school graduates, respectively, compared to university graduates. They were 0.372 points higher for those whose income was less than their expenditure compared to those whose income was balanced with their expenditure, 0.414 points higher in those who had experienced pain in the last 6 months compared to those who had not, and 0.561 points higher in those who did not use non-pharmacological methods in pain control compared to those who did. Those who expressed pain verbally were found to have points that were 0.447 higher than those who did not say they had pain.

Conclusion: Based on the results obtained, it is recommended that cancer patients be given training that will improve self-management and self-efficacy with cognitive-behavioral methods, taking into account their pain beliefs and affecting factors, in order for them to be successful in pain management.

目的:确定癌症患者的疼痛信念及相关因素。方法:本研究设计为描述性和分析性研究。该研究于2019年1月至6月完成,共有100名18岁或以上、正在接受化疗并同意参与该研究的人。使用患者信息表、疼痛评估表和疼痛信念量表收集数据。结果:在回归分析的结果中,行为紧张者的心理信念得分比行为冷静者高0.408分。与大学毕业生相比,基本识字和小学毕业生的有机信念得分分别高出0.814分和0.599分。收入低于支出的人比收入与支出平衡的人高0.372分,在过去6个月内经历过疼痛的人比没有经历过的人高0.414分,在疼痛控制中没有使用非药物方法的人比使用非药物的人高0.561分。那些口头表达疼痛的人比那些没有说自己疼痛的人高0.447分。结论:根据研究结果,建议对癌症患者进行认知行为方法的训练,以提高自我管理和自我效能,同时考虑他们的疼痛信念和影响因素,使他们在疼痛管理方面取得成功。
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引用次数: 0
The effect of consecutive facet medial branch radiofrequency denervation and dorsal root ganglion pulse radiofrequency therapy on lumbar facet joint pain. 连续小关节内侧支射频去神经和背根神经节脉冲射频治疗腰椎小关节疼痛的疗效。
IF 0.6 Q3 Medicine Pub Date : 2023-10-01 DOI: 10.14744/agri.2022.42713
Gazioğlu TürkyılmazGülçin, RumeliŞebnem

Objectives: The aim of this study was to evaluate the efficacy of consecutive facet medial branch (FMB) radiofrequency denervation (RFD) and dorsal root ganglion pulse radiofrequency (DRG PRF) therapy in patients with chronic lumbar facet joint pain.

Methods: The study included 27 patients with chronic lumbar pain who had ≥50% pain reduction after FMB block for suspected lumbar facet syndrome and subsequently underwent FMB RFD together with PRF to the adjacent DRG. The patients were retrospectively analyzed in terms of age, gender, pre-procedure symptom duration, history of previous back surgery, FMB RFD and DRG PRF level and side, and numerical rating scale scores immediately before and at 1, 3, and 6 months after the procedure, and subjective pain reduction at 6 months post-treatment. Treatment success was defined as ≥50% subjective pain reduction at 6 months.

Results: A total of 19 women and 8 men with a mean age of 57.7±12.4 years were analyzed. Twenty patients (74.1%) had no prior history of low back surgery. The success rate of the procedure in terms of subjective pain reduction at 6 months was 82.5% (n=25). The subjective percentage of pain reduction at post-procedure 6 months was significantly lower in patients with a pre-procedure symptom duration of 12 months or longer compared to those whose pre-procedure symptom duration was <12 months (p=0.04).

Conclusion: Our study results show that the analgesic efficiency of DRG PRF added to FMD RFD treatment can be increased in patients with short symptom durations.

目的:本研究旨在评估连续小关节内侧支(FMB)射频去神经支配(RFD)和背根神经节脉冲射频(DRG-PRF)治疗慢性腰小关节疼痛的疗效。方法:该研究纳入了27名慢性腰椎疼痛患者,他们在疑似腰椎小关节综合征的FMB阻滞后疼痛减轻≥50%,随后接受了FMB RFD和PRF对邻近DRG的治疗。回顾性分析患者的年龄、性别、术前症状持续时间、既往背部手术史、FMB RFD和DRG PRF水平和侧位、术前和术后1、3和6个月的数字评分量表评分,以及治疗后6个月主观疼痛减轻情况。治疗成功率定义为6个月时主观疼痛减轻≥50%。结果:共分析了19名女性和8名男性,平均年龄为57.7±12.4岁。20名患者(74.1%)既往无腰痛手术史。手术在6个月时主观疼痛减轻方面的成功率为82.5%(n=25)。与术前症状持续时间为12个月或更长的患者相比,术后6个月疼痛减轻的主观百分比显著更低。结论:我们的研究结果表明,在症状持续时间短的患者中,DRG-PRF加入FMD-RFD治疗的镇痛效率可以提高。
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引用次数: 0
Attention to soft tissues in hip pain: The importance of myofascial trigger point of the iliopsoas muscle in hip osteoarthritis. 髋关节疼痛时对软组织的关注:髂腰肌肌筋膜触发点在髋关节骨关节炎中的重要性。
IF 0.6 Q3 Medicine Pub Date : 2023-07-01 DOI: 10.14744/agri.2021.54837
Fatih Bağcıer, Ozan Volkan Yurdakul
{"title":"Attention to soft tissues in hip pain: The importance of myofascial trigger point of the iliopsoas muscle in hip osteoarthritis.","authors":"Fatih Bağcıer,&nbsp;Ozan Volkan Yurdakul","doi":"10.14744/agri.2021.54837","DOIUrl":"https://doi.org/10.14744/agri.2021.54837","url":null,"abstract":"","PeriodicalId":45603,"journal":{"name":"Agri-The Journal of the Turkish Society of Algology","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9873237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Agri-The Journal of the Turkish Society of Algology
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