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Jejunal Diverticular Bleeding on Long-Term Aspirin and Short-Term Corticosteroid Therapy. 长期阿司匹林和短期皮质类固醇治疗的空肠憩室出血。
IF 0.6 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-11-14 eCollection Date: 2024-01-01 DOI: 10.1155/crgm/8875482
Nikolaos Angelopoulos, William Beattie, Sern Wei Yeoh

Haemorrhage is one of the most common complications of jejunal diverticula, which is a challenge to diagnose as the anatomical location of the jejunum renders it inaccessible to standard upper endoscopy, while routine imaging modalities may miss subtle or intermittent bleeding. Male gender, increasing age and colonic diverticula are known risk factors for jejunal diverticula. Nonsteroidal anti-inflammatory drugs and corticosteroids increase gastrointestinal bleeding risk. We present a case of an 80-year-old male admitted to our hospital with syncope and melaena, in the setting of colonic diverticula, long-term aspirin and short-term corticosteroid therapy. Push enteroscopy, using a paediatric colonoscope, was pivotal to establishing the diagnosis of jejunal diverticular bleeding after gastroduodenoscopy and computed tomography (CT) angiogram were negative. Management was conservative with repeat push enteroscopy confirming the cessation of bleeding. Clinicians should consider this diagnosis when there are clinical signs of gastrointestinal bleeding in patients with known risk factors for jejunal diverticula and no evidence of location on gastroduodenoscopy, colonoscopy or imaging. We advise that push enteroscopy is performed early during the diagnostic workup to assist in identifying jejunal sources of bleeding and initiating management. However, as reflected by our case, jejunal diverticular haemorrhage may be amenable to conservative measures.

出血是空肠憩室最常见的并发症之一,其诊断具有挑战性,因为空肠的解剖位置使得标准上腔镜无法检测到,而常规成像方式可能会遗漏细微或间歇性出血。已知男性、年龄增长和结肠憩室是空肠憩室的危险因素。非甾体类抗炎药和皮质类固醇会增加胃肠道出血的风险。我们报告一例80岁男性因晕厥和黑黑而入院,在结肠憩室的情况下,长期服用阿司匹林和短期皮质类固醇治疗。在胃十二指肠镜检查和计算机断层扫描(CT)血管造影均为阴性的情况下,使用儿科结肠镜的推入式小肠镜检查对于确定空肠憩室出血的诊断至关重要。治疗是保守的,反复推肠镜确认出血停止。当已知空肠憩室危险因素的患者有消化道出血的临床体征,且在胃十二指肠镜、结肠镜或影像学检查中没有明确位置时,临床医生应考虑这种诊断。我们建议在诊断检查的早期进行推肠镜检查,以帮助确定空肠出血的来源和开始处理。然而,正如我们的病例所反映的,空肠憩室出血可以采取保守措施。
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引用次数: 0
Laparoscopic Cholecystectomy for Gall Bladder Volvulus: A Report of an Original Case With Review of Literature. 腹腔镜胆囊切除术治疗胆囊肿物:一个原始病例的报告及文献综述。
IF 0.6 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-11-04 eCollection Date: 2024-01-01 DOI: 10.1155/2024/9319605
Ayad Ahmad Mohammed

Background: Volvulus of gallbladder is defined as a rotation of the gallbladder on its mesentery along the axis of the cystic duct and cystic artery. Many factors are postulated to be the causes such as anatomical, mechanical, physiological, and hormonal risk factors but the presence of a distended gallbladder with a redundant mesentery is thought to be an important cause. Case presentation: A 68-year-old woman presented with right hypochondrial pain and vomiting for 2 days that was radiated to the interscapular region and associated with nausea and vomiting. The patient had no jaundice and the abdominal examination showed severe tenderness with guarding during palpation of the right upper abdomen with no palpable mass. The WBCs were elevated, with normal liver enzymes, bilirubin, and alkaline phosphatase. The ultrasound showed a single gallstone with increased wall thickness. There was no significant clinical improvement with antibiotics and analgesics. During laparoscopy, volvulus of the gallbladder was discovered causing gangrene of the gallbladder. Laparoscopic detorsion and successful laparoscopic cholecystectomy were performed. The patient was discharged on the third postoperative day with dramatic improvement with no postoperative complications. Conclusion: Gall bladder volvulus is an acute surgical emergency that is usually seen in the elderly population. It required a high index of suspicion especially in the absence of gallstones and must be differentiated from acalculous cholecystitis. Most cases are discovered at surgery. It must be managed with immediate detorsion and cholecystectomy, and the prognosis is excellent in most cases after an appropriate surgical intervention.

背景:胆囊肿胀是指胆囊沿胆囊管和胆囊动脉的轴线在其系膜上旋转。许多因素被认为是导致胆囊肿胀的原因,如解剖、机械、生理和荷尔蒙风险因素,但存在膨胀的胆囊和多余的系膜被认为是一个重要原因。病例介绍:一名 68 岁的妇女因右下腹疼痛和呕吐就诊,疼痛和呕吐已持续 2 天,并向肩胛间区域放射,还伴有恶心和呕吐。患者无黄疸,腹部检查显示右上腹触诊时有严重压痛并伴有戒备,但未触及肿块。白细胞升高,肝酶、胆红素和碱性磷酸酶正常。超声波检查显示有一块胆石,石壁厚度增加。服用抗生素和镇痛药后,临床症状没有明显改善。腹腔镜检查时发现胆囊肿胀,导致胆囊坏疽。患者接受了腹腔镜胆囊切除术。患者在术后第三天出院,病情明显好转,没有出现术后并发症。结论胆囊内翻是一种急性外科急症,通常见于老年人群。需要高度怀疑,尤其是在没有胆结石的情况下,并且必须与结石性胆囊炎相鉴别。大多数病例都是在手术中发现的。必须立即进行剥离和胆囊切除术,经过适当的手术干预后,大多数病例的预后都很好。
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引用次数: 0
VCTE Overestimates Liver Fibrosis due to Abdominal-Truncal Adiposity and Not Hepatic Steatosis: A Case Report. VCTE 高估了腹部和躯干脂肪过多导致的肝纤维化,而非肝脏脂肪变性:病例报告
IF 0.6 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-10-28 eCollection Date: 2024-01-01 DOI: 10.1155/2024/7938701
Jordan S Woodard, Jena Velji-Ibrahim, Jay Alden, Gary A Abrams

Vibration-controlled transient elastography (VCTE) is used for the noninvasive assessment of liver fibrosis. We present a case of significant weight loss over 1 year, resulting in a marked improvement in liver stiffness suggesting a decrease in liver fibrosis from stage 4 (cirrhosis) to stage 2 (moderate fibrosis) notably without a change in the grade of hepatic steatosis. The improvement in two stages of fibrosis over this short time frame is due to the overestimation of liver stiffness in a subject with class 3 obesity and not due to the resolution of fibrosis. Therefore, this case highlights that BMI, due to excess subcutaneous abdominal adipose tissue and not intrahepatic lipid accumulation, can cause a significant overestimation of liver fibrosis with VCTE.

振动控制瞬态弹性成像(VCTE)用于对肝纤维化进行无创评估。我们介绍了一例在一年内体重明显下降的病例,其结果是肝脏硬度明显改善,表明肝纤维化从第 4 期(肝硬化)下降到第 2 期(中度纤维化),但肝脏脂肪变性的等级没有发生变化。在这么短的时间内,两期肝纤维化的改善是由于高估了 3 级肥胖症患者的肝脏硬度,而不是由于肝纤维化的缓解。因此,本病例突出表明,由于腹部皮下脂肪组织过多而不是肝内脂质堆积,BMI 可导致 VCTE 对肝纤维化的显著高估。
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引用次数: 0
Cervical Chylous Leakage Combined With Chylothorax: A Case Report of a Rare Complication Postretroperitoneal Surgery and Its Management: A Case Report of Chylous Leakage. 颈部乳糜漏合并乳糜胸:腹膜后手术后罕见并发症及其处理的病例报告:乳糜泻病例报告。
IF 0.6 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-10-22 eCollection Date: 2024-01-01 DOI: 10.1155/2024/8820322
Yao Zhou, Mingde Ding, Qiang Shi, Jing Wang, Guanghai Liu, Qianqian Zhang

Chylous leakage is an uncommon and serious clinical condition, especially occurring after retroperitoneal operations. Here, we report a case of cervical chylous leakage combined with chylothorax in a 57-year-old woman postretroperitoneal surgery, and our conservative approach led to resolution/clinical improvement. The causes of this rare complication are discussed. We considered that the venous thrombosis, the increased intra-abdominal pressure, or the patient positioning during the surgery may lead to the chylous particles leakage and chylothorax. Because of its rarity, we hope this case report will improve clinicians' understanding of cervical chylous leakage combined with chylothorax and provide suitable treatment options for future clinical reference.

乳糜漏是一种不常见的严重临床症状,尤其发生在腹膜后手术后。在此,我们报告了一例 57 岁女性腹膜后手术后颈部乳糜液渗漏合并乳糜胸的病例,我们采取的保守治疗方法使病情得到了缓解/临床改善。我们讨论了这种罕见并发症的原因。我们认为,静脉血栓、腹腔内压力增高或手术中患者的体位都可能导致乳糜微粒渗漏和乳糜胸。由于其罕见性,我们希望本病例报告能提高临床医生对宫颈乳糜漏合并乳糜胸的认识,并提供合适的治疗方案供今后临床参考。
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引用次数: 0
Rectal Adenocarcinoma With Pagetoid Spread: A Novel Entity. 伴有片状扩散的直肠腺癌:一种新的实体。
IF 0.6 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-10-21 eCollection Date: 2024-01-01 DOI: 10.1155/2024/4952952
Lefika Bathobakae, Pasha Shenasan, Aakash Trivedi, Ruhin Yuridullah, Sohail Qayyum, Abraham El-Sedfy

Perianal Paget's disease (PPD) is a rare skin adenocarcinoma that arises in the apocrine glands of the perianal region. It is often misdiagnosed as eczema, leukoplakia, squamous cell carcinoma, Bowen's disease, lichen planus, or condylomata acuminata. We report a case of a 63-year-old male who presented to the emergency room (ER) for evaluation of an anal mass that had persisted over 6 months. The patient was found to have a rectal adenocarcinoma with pagetoid spread and underwent neoadjuvant chemoradiation with symptom improvement. However, the patient declined further chemotherapy and the planned abdominal perineal resection with reconstruction, as it would require a permanent colostomy.

肛周帕吉特氏病(PPD)是一种罕见的皮肤腺癌,发生于肛周的分泌腺。它常被误诊为湿疹、白斑病、鳞状细胞癌、鲍温氏病、扁平苔藓或尖锐湿疣。我们报告了一例 63 岁男性患者的病例,他因肛门肿块持续 6 个月之久到急诊室就诊。经检查发现,患者患有直肠腺癌,并伴有腺样体扩散,患者接受了新辅助化疗,症状有所改善。然而,患者拒绝接受进一步化疗和腹部会阴部切除与重建计划,因为这需要永久性结肠造口。
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引用次数: 0
White Globe Appearance-Like Findings Indicating Intralymphatic Cancer Involvement Beneath the Epithelium in Gastric Cancer. 显示胃癌上皮下淋巴内癌受累的白球样发现
IF 0.6 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-10-19 eCollection Date: 2024-01-01 DOI: 10.1155/2024/8504987
Hiroki Maruyama, Taku Yamagata, Yoshihide Kanno, Takeshi Shimizu, Takuho Itasaka, Fumiyoshi Fujishima, Takashi Sawai, Kei Ito

A 75-year-old female was diagnosed with a type 0-I, moderately differentiated, early gastric carcinoma on the posterior wall of the middle gastric body during esophagogastroduodenoscopy (EGD). Several small whitish structures, referred to as white globe appearances (WGAs), were noted on the oral side outside the demarcation line of the cancerous protrusion. Although this area was flat without cancerous mucosal changes on the surface, subepithelial cancer extension was suspected. The histopathology of the resected specimen revealed that the carcinoma with submucosal invasion had significant lymphatic invasion with submucosal lateral extent along lymphatic vessels. In some areas, the carcinoma within the lymphatic vessels regressed from the submucosal layer towards the mucosal lamina propria, penetrating the muscularis mucosas. The intralymphatic carcinoma reaching just beneath the epithelium was considered to manifest WGA features during endoscopy.

一名 75 岁的女性在接受食管胃十二指肠镜检查(EGD)时被确诊为中胃体后壁上的 0-I 型中度分化早期胃癌。在癌突起分界线外的口腔侧发现了几个小的白色结构,称为白球外观(WGA)。虽然该区域平坦,表面没有癌变粘膜,但怀疑是上皮下癌延伸。切除标本的组织病理学检查显示,粘膜下浸润癌有明显的淋巴管浸润,沿淋巴管向粘膜下侧扩展。在某些区域,淋巴管内的癌细胞从粘膜下层向粘膜固有层退缩,穿透粘膜肌层。在内窥镜检查中,淋巴管内癌刚好到达上皮下方,被认为具有 WGA 特征。
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引用次数: 0
Fluoroscopic-Guided Removal of Jejunal Sharp Foreign Body: An Alternative Approach to Surgery. 透视引导下的空肠尖锐异物取出术:手术的另一种方法。
IF 0.6 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-09-16 eCollection Date: 2024-01-01 DOI: 10.1155/2024/5117360
Abdulrahman Qatomah, Simon McQueen, Wafa Qatomah, Aishah Qatomah, Ali Bessissow

Introduction: Foreign body (FB) ingestion represents a frequently encountered scenario in clinical practice. Most ingested FBs typically pass spontaneously, requiring no intervention. Endoscopic removal stands out as the least invasive method, with only a minimal 1% needing surgical intervention. Case Presentation. We present a case of a 30-year-old male who ingested multiple FBs located in the stomach and small bowel. While successful removal of the stomach FB was achieved through endoscopy, the second FB in the small bowel proved challenging due to perforation concerns and limited expertise. Given a history of prior surgical intervention resulting in a large incisional hernia, surgical removal was discouraged. Consequently, a collaborative decision involving surgeon and interventional radiologist (IR) led to the adoption of a fluoroscopic-guided removal approach facilitated by IR techniques.

Conclusion: This case highlights the potential for a less invasive alternative in situations where both endoscopic and surgical interventions are deemed not feasible.

导言:异物(FB)摄入是临床实践中经常遇到的情况。大多数误食的异物通常会自行排出,无需干预。内窥镜取出异物是创伤最小的方法,只有极少的 1%需要手术干预。病例介绍。我们介绍了一例 30 岁男性的病例,他摄入了位于胃部和小肠的多个 FB。虽然通过内窥镜成功切除了胃中的 FB,但由于穿孔问题和专业知识有限,切除小肠中的第二个 FB 证明具有挑战性。考虑到患者之前曾因手术治疗导致大切口疝,医生不建议进行手术切除。因此,在外科医生和介入放射科医生(IR)的共同决定下,在 IR 技术的帮助下采用了透视引导下的切除方法:本病例凸显了在内窥镜和外科手术均不可行的情况下,采用创伤较小的替代方法的可能性。
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引用次数: 0
Severe Airway Obstruction Caused by Esophageal Bezoar with Coca-Cola and Creon (Pancrelipase) in a Patient with Underlying Achalasia: A Comprehensive Case Report. 一名有潜在食道闭锁的患者因使用可口可乐和 Creon(Pancrelipase)造成食道溃疡而导致严重气道阻塞:一份综合病例报告。
IF 0.6 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-07-27 eCollection Date: 2024-01-01 DOI: 10.1155/2024/2081040
Kinnera Sahithi Urlapu, Nikhitha Mantri, Harish Patel, Priscilla Lajara Hallal, Sridhar Chilimuri, Gilda Diaz-Fuentes

Introduction: The occurrence of acute respiratory failure as a result of esophageal bezoars is a rare phenomenon. We present a patient who failed initial endoscopic intervention. Successful resolution was achieved through a novel approach involving a combination of Creon and Coca-Cola. Subsequently, the patient was diagnosed with achalasia, a condition that potentially contributed to the formation of the esophageal bezoar. Case Description. An 82-year-old man presented with respiratory distress, necessitating endotracheal intubation for airway protection. A chest computed tomogram (CT) showed pneumonia and a distended esophagus compressing the trachea, raising the possibility of an esophageal food bolus. Endoscopy revealed a severely dilated esophagus containing a significant amount of food and a phytobezoar in the lower esophagus. He failed various endoscopic techniques to remove the obstruction. Given the patient's poor surgical candidacy, he was started in a thrice-daily regimen of Creon dissolved in 165 mL of Coca-Cola, over a 4-day period. A subsequent endoscopy revealed no discernible evidence of food or bezoar. The patient was weaned from mechanical ventilation. A high-resolution esophageal manometry identified type 1 achalasia.

Conclusion: Esophageal food impaction leading to respiratory failure is rare. Endoscopy remains the mainstay approach. Surgical interventions carry significant risks. This case emphasizes the potential for noninvasive management in patients with esophageal bezoars and also underscores the significance of contemplating esophageal pathologies when addressing cases of respiratory failure. The use of Coca-Cola and Creon emerges as a safe, effective, and cost-efficient treatment, providing a feasible option when endoscopy proves unsuccessful before considering more aggressive interventions.

简介因食道大泡而导致急性呼吸衰竭是一种罕见的现象。我们为您介绍一名最初内镜介入治疗失败的患者。通过使用克瑞恩和可口可乐的新方法,成功解决了问题。随后,患者被诊断出患有贲门失弛缓症,这种疾病可能是食道软泡形成的原因之一。病例描述。一名 82 岁的男性出现呼吸困难,必须进行气管插管以保护气道。胸部计算机断层扫描(CT)显示存在肺炎,膨胀的食管压迫气管,这提高了食管食物栓的可能性。内窥镜检查显示食管严重扩张,食管下段含有大量食物和植物虫。他未能通过各种内镜技术清除梗阻。鉴于患者不适合手术治疗,医生让他在 4 天内每天三次服用溶解在 165 毫升可口可乐中的克里翁。随后的内窥镜检查没有发现食物或牛粪的迹象。患者已脱离机械通气。高分辨率食管测压发现了 1 型贲门失弛缓症:结论:食管食物嵌塞导致呼吸衰竭的情况非常罕见。内镜检查仍是主要方法。手术干预具有重大风险。本病例强调了对食管息肉患者进行无创治疗的可能性,同时也强调了在处理呼吸衰竭病例时考虑食管病变的重要性。使用可口可乐和克里翁是一种安全、有效、经济的治疗方法,当内窥镜检查不成功时,在考虑采取更积极的干预措施之前提供了一种可行的选择。
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引用次数: 0
Pneumothorax, Pneumomediastinum, and Cervical and Facial Massive Emphysema Secondary to Colonoscopy: A Rare Complication of Colonoscopy. 结肠镜检查继发气胸、气胸、颈部和面部大面积气肿:结肠镜检查的罕见并发症。
IF 0.6 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-06-25 eCollection Date: 2024-01-01 DOI: 10.1155/2024/1140099
Ruben Daniel Perez Lopez, Julian Vargas Flores, Lenin de Jesus Orbe Garibay, Hugo Fernando Narvaez Gonzalez

Background: Colonoscopy is a resource used for the diagnosis, treatment, and monitoring of benign and malignant colorectal pathologies. The incidence of perforation is 0.03%-0.65% in diagnostic colonoscopy; however, the incidence can be up to 10 times higher in therapeutic interventions, such as polypectomies, increasing the risk of complications up to 0.07-2.1%. Materials and methods. Case report of a 71-year-old female who presents a rare complication due to a perforation in the sigmoid which developed pneumoperitoneum, pneumomediastinum, pneumothorax, and massive subcutaneous emphysema as a complication of a diagnostic colonoscopy where a biopsy of a friable lesion was performed.

Results: A 71-year-old female that went to the emergency room due to acute generalized abdominal colic spasm pain with a duration of 7 hours, associated with significant abdominal distension, malaise, diaphoresis, progressive dyspnea, and massive subcutaneous emphysema that developed after performing panendoscopy and colonoscopy for diverticulosis follow-up. An abdominal CT scan with double contrast was performed, reporting suggestive data of hollow viscus perforation, pneumoperitoneum, pneumomediastinum, pneumothorax, and massive subcutaneous emphysema in the thorax, neck, and skull base. She underwent an exploratory laparotomy finding a perforation in the sigmoid for which sigmoidectomy was performed, and for the pneumothorax and pneumomediastinum, endopleural tubes were placed in both hemithoraxes. The massive subcutaneous emphysema subsided with observation and oxygen.

Conclusion: A rare complication of the use of colonoscopy as a diagnostic and therapeutic method is presented. The purpose of presenting this case is for the doctor who performs these interventions to suspect this complication in a timely manner, not delaying the diagnosis and carrying out an urgent therapeutic approach as in this case with exploratory laparotomy, finding the perforation site and carrying out the corresponding surgical management. We demonstrated that massive subcutaneous emphysema can be managed with observation if there is no other alarm data evident that required another surgical approach.

背景:结肠镜检查是诊断、治疗和监测良性和恶性结肠直肠病变的一种手段。在诊断性结肠镜检查中,穿孔的发生率为 0.03%-0.65%;然而,在治疗性干预(如息肉切除术)中,穿孔的发生率可高达 10 倍,并发症的风险增加到 0.07-2.1%。材料和方法。该病例报告了一名 71 岁女性因乙状结肠穿孔而引发的罕见并发症,她在诊断性结肠镜检查中对易碎病灶进行了活检,结果并发腹腔积气、气胸、气胸和大量皮下气肿:一位71岁的女性因急性全身腹部绞痛痉挛性疼痛前往急诊室就诊,疼痛持续了7个小时,伴有明显的腹胀、乏力、全身舒张、进行性呼吸困难和大量皮下气肿。她接受了腹部双对比 CT 扫描,结果显示空腔脏器穿孔、腹腔积气、纵隔积气、气胸以及胸部、颈部和颅底大面积皮下气肿。她接受了探查性开腹手术,发现乙状结肠穿孔,因此进行了乙状结肠切除术。通过观察和吸氧,大量皮下气肿消退:结肠镜检查作为一种诊断和治疗方法,出现了一种罕见的并发症。介绍该病例的目的是让医生在进行这些干预时及时怀疑这种并发症,不要延误诊断,并采取紧急治疗方法,就像本病例中的探查性开腹手术一样,找到穿孔部位并进行相应的手术治疗。我们的研究表明,如果没有其他明显的报警数据需要采取其他手术方法,大面积皮下气肿可以通过观察进行处理。
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引用次数: 0
Endoscopic Resection of Tailgut Cyst. 尾肠囊肿内窥镜切除术
IF 0.6 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-06-11 eCollection Date: 2024-01-01 DOI: 10.1155/2024/5538439
Oleksandr Kiosov, Vladyslav Tkachov, Sergii Gulevskyi

Tailgut cyst or retrorectal cystic hamartoma is a rare congenital lesion, thought to arise from a portion of the embryological hindgut, usually benign, with no or unspecific symptoms, mainly diagnosed in middle-aged women. Complete surgical resection of the cyst is recommended to avoid complications and confirm the diagnosis. In this report, we present our experience in the successful endoscopic management of a tailgut cyst, outlining the endoscopic resection technique and discussing under what conditions this approach may be applicable.

尾肠囊肿或直肠后囊肿是一种罕见的先天性病变,被认为来自胚胎后肠的一部分,通常为良性,无特异性症状或症状不明显,主要在中年女性中确诊。为避免并发症并确诊,建议对囊肿进行彻底手术切除。在本报告中,我们介绍了成功通过内窥镜治疗尾肠囊肿的经验,概述了内窥镜切除技术,并讨论了这种方法适用于哪些情况。
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引用次数: 0
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Case Reports in Gastrointestinal Medicine
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