Calcium channel blockers (CCBs) are the first-line treatment for coronary artery spasm (CAS). When CAS-related angina symptoms are not well controlled by CCB therapy, long-acting nitrates or (where available) nicorandil can be added as second-line medications. In the case of CAS refractory to standard treatments, several other alternative drugs and interventions have been proposed, including the Rho-kinase inhibitor fasudil, anti-adrenergic drugs, neural therapies and percutaneous coronary interventions. In patients with syncope or cardiac arrest caused by CAS-related tachyarrhythmias, or even bradyarrhythmias, implantation of an ICD or pacemaker, respectively, should be considered according to the risk of recurrence and efficacy of vasodilator therapy.
{"title":"Management of Coronary Artery Spasm.","authors":"Gaetano Antonio Lanza, Hiroaki Shimokawa","doi":"10.15420/ecr.2022.47","DOIUrl":"https://doi.org/10.15420/ecr.2022.47","url":null,"abstract":"<p><p>Calcium channel blockers (CCBs) are the first-line treatment for coronary artery spasm (CAS). When CAS-related angina symptoms are not well controlled by CCB therapy, long-acting nitrates or (where available) nicorandil can be added as second-line medications. In the case of CAS refractory to standard treatments, several other alternative drugs and interventions have been proposed, including the Rho-kinase inhibitor fasudil, anti-adrenergic drugs, neural therapies and percutaneous coronary interventions. In patients with syncope or cardiac arrest caused by CAS-related tachyarrhythmias, or even bradyarrhythmias, implantation of an ICD or pacemaker, respectively, should be considered according to the risk of recurrence and efficacy of vasodilator therapy.</p>","PeriodicalId":45957,"journal":{"name":"European Cardiology Review","volume":"18 ","pages":"e38"},"PeriodicalIF":3.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/dc/58/ecr-18-e38.PMC10345953.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9825940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.15420/ecr.2023.18.PO12
J Lesmana, A Lefi
{"title":"The Relationship between Neutrophil to Lymphocyte Ratio with Rehospitalisation and Mortality in Patients with Acute Coronary Syndrome.","authors":"J Lesmana, A Lefi","doi":"10.15420/ecr.2023.18.PO12","DOIUrl":"https://doi.org/10.15420/ecr.2023.18.PO12","url":null,"abstract":"","PeriodicalId":45957,"journal":{"name":"European Cardiology Review","volume":"18 ","pages":"e29"},"PeriodicalIF":3.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/15/37/ecr-18-e29.PMC10316359.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10160561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.15420/ecr.2023.18.PO11
Harlokesh Narayan Yadav, Sadia Shah
{"title":"Effect of Vitamin D in Experimental Pulmonary Arterial Hypertension in Rats: Possible Role of eNOS-mediated Signalling Pathways.","authors":"Harlokesh Narayan Yadav, Sadia Shah","doi":"10.15420/ecr.2023.18.PO11","DOIUrl":"https://doi.org/10.15420/ecr.2023.18.PO11","url":null,"abstract":"","PeriodicalId":45957,"journal":{"name":"European Cardiology Review","volume":"18 ","pages":"e28"},"PeriodicalIF":3.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ea/d3/ecr-18-e28.PMC10316370.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9793289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.15420/ecr.2023.18.PO2
N Mallofré, G Torres, C Roca, P Rojas, M Sutil, N Casanovas, M Lloreda, F Castaldo, E Bosch, A Martínez-Rubio
{"title":"Oral Presentation Award Winner: LDL-C Reduction in Diabetic Patients after Percutaneous Coronary Intervention: Is There any Difference with Non-diabetic?","authors":"N Mallofré, G Torres, C Roca, P Rojas, M Sutil, N Casanovas, M Lloreda, F Castaldo, E Bosch, A Martínez-Rubio","doi":"10.15420/ecr.2023.18.PO2","DOIUrl":"https://doi.org/10.15420/ecr.2023.18.PO2","url":null,"abstract":"","PeriodicalId":45957,"journal":{"name":"European Cardiology Review","volume":"18 ","pages":"e19"},"PeriodicalIF":3.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a2/2f/ecr-18-e19.PMC10316379.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9793291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.15420/ecr.2023.18.PO20
Yii Ching Wong
{"title":"Use of Heart Failure-Exacerbating Medications among Heart Failure Patients in a Tertiary Referral Centre in Malaysia.","authors":"Yii Ching Wong","doi":"10.15420/ecr.2023.18.PO20","DOIUrl":"https://doi.org/10.15420/ecr.2023.18.PO20","url":null,"abstract":"","PeriodicalId":45957,"journal":{"name":"European Cardiology Review","volume":"18 ","pages":"e37"},"PeriodicalIF":3.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/50/e1/ecr-18-e37.PMC10316340.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9802291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.15420/ecr.2023.18.PO19
V Blaha, R Margoczy, I Petrov, A Postadzhiyan, K Raslova, H Rosolova, I Bridges, N N Dhalwani, M Zachlederova, K K Ray
{"title":"Evolocumab is initiated in Central and Eastern Europe at Much Higher LDL-C Levels than Recommended in Guidelines: Results from the Observational HEYMANS Study.","authors":"V Blaha, R Margoczy, I Petrov, A Postadzhiyan, K Raslova, H Rosolova, I Bridges, N N Dhalwani, M Zachlederova, K K Ray","doi":"10.15420/ecr.2023.18.PO19","DOIUrl":"https://doi.org/10.15420/ecr.2023.18.PO19","url":null,"abstract":"","PeriodicalId":45957,"journal":{"name":"European Cardiology Review","volume":"18 ","pages":"e36"},"PeriodicalIF":3.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d9/cb/ecr-18-e36.PMC10316339.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9802292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}