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Management of Coronary Artery Spasm. 冠状动脉痉挛的治疗。
IF 3 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
European Cardiology Review
Pub Date : 2023-01-01 DOI: 10.15420/ecr.2022.47
Gaetano Antonio Lanza, Hiroaki Shimokawa

Calcium channel blockers (CCBs) are the first-line treatment for coronary artery spasm (CAS). When CAS-related angina symptoms are not well controlled by CCB therapy, long-acting nitrates or (where available) nicorandil can be added as second-line medications. In the case of CAS refractory to standard treatments, several other alternative drugs and interventions have been proposed, including the Rho-kinase inhibitor fasudil, anti-adrenergic drugs, neural therapies and percutaneous coronary interventions. In patients with syncope or cardiac arrest caused by CAS-related tachyarrhythmias, or even bradyarrhythmias, implantation of an ICD or pacemaker, respectively, should be considered according to the risk of recurrence and efficacy of vasodilator therapy.

钙通道阻滞剂(CCBs)是治疗冠状动脉痉挛(CAS)的一线药物。当CCB治疗不能很好地控制cas相关心绞痛症状时，可添加长效硝酸盐或(如有)尼可地尔作为二线药物。在标准治疗难治性CAS的情况下，已经提出了几种其他替代药物和干预措施，包括rho激酶抑制剂法舒地尔、抗肾上腺素能药物、神经疗法和经皮冠状动脉介入治疗。对于由cas相关性快速心律失常，甚至慢速心律失常引起的晕厥或心脏骤停患者，应根据复发风险和血管扩张剂治疗效果，分别考虑植入ICD或起搏器。
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引用次数: 2
Long-term Mortality Predictors of Patients Evaluated with Pharmacologic Cardiac Stress SPECT (PS-SPECT) for Suspicion of Chronic Coronary Syndrome. 用药理学心脏应激SPECT (PS-SPECT)评估疑似慢性冠脉综合征患者的长期死亡率预测因素。
IF 3 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
European Cardiology Review
Pub Date : 2023-01-01 DOI: 10.15420/ecr.2023.18.PO16
Nuria Mallofré
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引用次数: 0
The Relationship between Neutrophil to Lymphocyte Ratio with Rehospitalisation and Mortality in Patients with Acute Coronary Syndrome. 急性冠脉综合征患者中性粒细胞与淋巴细胞比值与再住院及死亡率的关系。
IF 3 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
European Cardiology Review
Pub Date : 2023-01-01 DOI: 10.15420/ecr.2023.18.PO12
J Lesmana, A Lefi
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引用次数: 0
Effect of Vitamin D in Experimental Pulmonary Arterial Hypertension in Rats: Possible Role of eNOS-mediated Signalling Pathways. 维生素D在实验性肺动脉高压大鼠中的作用:enos介导的信号通路的可能作用。
IF 3 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
European Cardiology Review
Pub Date : 2023-01-01 DOI: 10.15420/ecr.2023.18.PO11
Harlokesh Narayan Yadav, Sadia Shah
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引用次数: 0
HDL Mimetics Enhances Mitochondrial Function via Stimulation of PGC1-α. HDL模拟物通过刺激PGC1-α增强线粒体功能。
IF 3 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
European Cardiology Review
Pub Date : 2023-01-01 DOI: 10.15420/ecr.2023.18.PO10
Hang Zhang, Tomohiro Komatsu, Shihoko Nakashima, Satomi Abe, Emi Kawachi, Satoshi Imaizumi, Keijiro Saku, Yoshinari Uehara
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引用次数: 0
Coronary Spasm: Ethnic and Sex Differences. 冠状动脉痉挛:种族和性别差异。
IF 3 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
European Cardiology Review
Pub Date : 2023-01-01 DOI: 10.15420/ecr.2023.13
Peter Ong, Astrid Hubert, Maike Schwidder, John F Beltrame

Coronary spasm (CS), which may occur at the epicardial (focal or diffuse spasm) and/or microvascular (microvascular spasm) level, is a well-established cause of myocardial ischaemia, in particular in patients with anginal chest pain despite unobstructed coronary arteries. The diagnosis of CS can be confirmed during coronary angiography by an additional provocation test with vasoactive substances such as acetylcholine. Due to partially inconsistent data from large clinical studies, especially between Asian and white CS patients, ethnic differences concerning the prevalence and angiographic patterns of CS seem to exist. Furthermore, several studies in patients with coronary vasomotor disorders pointed towards differences among male and female CS patients. This article gives an overview of ethnic- and sex-related differences in patients with CS.

冠状动脉痉挛(CS)可能发生在心外膜(局灶性或弥漫性痉挛)和/或微血管(微血管痉挛)水平，是心肌缺血的一个公认原因，特别是在冠状动脉通畅的心绞痛胸痛患者中。CS的诊断可以在冠状动脉造影时通过血管活性物质(如乙酰胆碱)的额外激发试验来证实。由于大型临床研究的部分数据不一致，特别是在亚洲和白人CS患者之间，CS的患病率和血管造影模式似乎存在种族差异。此外，一些对冠状动脉血管舒缩性疾病患者的研究表明，男性和女性CS患者存在差异。本文概述了CS患者的种族和性别相关差异。
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引用次数: 1
Use of Heart Failure-Exacerbating Medications among Heart Failure Patients in a Tertiary Referral Centre in Malaysia. 在马来西亚三级转诊中心心力衰竭患者中使用心力衰竭加重药物。
IF 3 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
European Cardiology Review
Pub Date : 2023-01-01 DOI: 10.15420/ecr.2023.18.PO20
Yii Ching Wong
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引用次数: 0
Evolocumab is initiated in Central and Eastern Europe at Much Higher LDL-C Levels than Recommended in Guidelines: Results from the Observational HEYMANS Study. Evolocumab在中欧和东欧的LDL-C水平比指南中推荐的高得多的患者中开始使用:观察性HEYMANS研究的结果。
IF 3 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
European Cardiology Review
Pub Date : 2023-01-01 DOI: 10.15420/ecr.2023.18.PO19
V Blaha, R Margoczy, I Petrov, A Postadzhiyan, K Raslova, H Rosolova, I Bridges, N N Dhalwani, M Zachlederova, K K Ray
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引用次数: 0
Difficulties in Monitoring Antithrombotic Therapy in Patients with Atrial Fibrillation and Post-traumatic Hepatic and Splenic Visceral Haematomas. 心房颤动和创伤后肝、脾脏器血肿患者抗血栓治疗监测的困难。
IF 3 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
European Cardiology Review
Pub Date : 2023-01-01 DOI: 10.15420/ecr.2023.18.PO14
Maria Cristina Beznă, Suzana Dănoiu, Marinela Beznă, Iulia-Andreea Voișneanu, Amelia Genunche-Dumitrescu, Larisa Săndulescu
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引用次数: 0
Approach to Anticoagulation Therapy in Patients with Combined Atrial Fibrillation and Coronary Artery Stents: A Review of the Literature. 房颤合并冠状动脉支架患者的抗凝治疗方法:文献综述。
IF 3 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
European Cardiology Review
Pub Date : 2023-01-01 DOI: 10.15420/ecr.2023.18.PO4
Ben Borokhovsky, Perry J Weinstock
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引用次数: 0
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