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Invasive versus non-invasive ventilation in patients with COVID-19 pneumonia: A retrospective study COVID-19肺炎患者有创与无创通气的回顾性研究
IF 0.5 Q4 CRITICAL CARE MEDICINE Pub Date : 2023-01-01 DOI: 10.4103/2221-6189.374312
Abhijit S. Nair, Jacob Paul, A. Yadav, Khalid M Al Sawafi
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引用次数: 0
Incidence rate of animal bites in southern Iran during 2015-2019 using Cochrane-Armitage trend test 2015-2019年伊朗南部动物咬伤发生率(Cochrane-Armitage趋势检验
IF 0.5 Q4 CRITICAL CARE MEDICINE Pub Date : 2023-01-01 DOI: 10.4103/2221-6189.369076
Hamed Delam, A. Eidi, Z. Keshtkaran, O. Soufi, Behzad Rezaei, Mohammad-Rafi Bazrafshan
Objective: To investigate the trend of animal bites in southern Iran from 2015 to 2019. Methods: This is a cross-sectional study of patients with animal bites who were referred to the Center for Disease Control in the three cities of Larestan, Evaz, and Khonj in Fars province, southern Iran from 2015 to 2019. The trend of animal bites incidence was analyzed using the Cochran-Armitage trend test. Results: In total, from 2015 to 2019, 1 944 cases of animal bites were reported. A total of 79.8% of the cases were men. The overall average incidence of animal bites was 142.93 per 100 000 people. The incidence of animal bites was significantly increased (Ptrend<0.001). The highest incidence was in November (79.04 per 100 000 people) followed by January (76.1 per 100 000 people) and February (69.48 per 100 000 people); also, the lowest incidence was in August (47.42 per 100 000 people) and July (50.0 per 100 000 people). Conclusions: The incidence of animal bites has significantly increased. Given the importance of rabies, control and management of animal bites should be emphasized and considered.
目的:调查2015-2019年伊朗南部动物咬伤的趋势。方法:这是一项横断面研究,研究对象是2015年至2019年在伊朗南部法尔斯省的拉雷斯坦、埃瓦兹和孔杰三个城市转诊至疾病控制中心的动物咬伤患者。采用Cochran-Armitage趋势检验对动物咬伤发生率的趋势进行分析。结果:2015年至2019年,共报告了1 944例动物咬伤病例。79.8%的病例为男性。动物咬伤的总体平均发生率为每10万人142.93。动物咬伤的发生率显著增加(P趋势<0.001)。11月发生率最高(79.04/10万人),其次是1月(76.1/100万人)和2月(69.48/10万人);发病率最低的是8月(每10万人47.42)和7月(每100万人50.0)。结论:动物咬伤的发生率显著增加。鉴于狂犬病的重要性,应重视和考虑对动物咬伤的控制和管理。
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引用次数: 0
Correlation of umbilical cord blood pH, base deficit, and lactate levels with outcomes of hypoxic newborns: A prospective study 脐带血pH值、碱性缺陷和乳酸水平与新生儿缺氧结局的相关性:一项前瞻性研究
IF 0.5 Q4 CRITICAL CARE MEDICINE Pub Date : 2023-01-01 DOI: 10.4103/2221-6189.379275
SanaSalim Khan, Sumbul Qamar, M. Ansari, JN Mohapatra
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引用次数: 0
General awareness of symptoms of myocardial infarction and the need for urgent treatment: A cross-sectional, street survey in Chennai, Tamil Nadu 对心肌梗死症状的普遍认识和紧急治疗的需要:在泰米尔纳德邦金奈的横断面街道调查
IF 0.5 Q4 CRITICAL CARE MEDICINE Pub Date : 2023-01-01 DOI: 10.4103/2221-6189.374310
Thirumurugan E, G. K, Swathy P, Afrin Syed Ali, Alekhya Ponduri Lakshmi, J. B, B. Das
{"title":"General awareness of symptoms of myocardial infarction and the need for urgent treatment: A cross-sectional, street survey in Chennai, Tamil Nadu","authors":"Thirumurugan E, G. K, Swathy P, Afrin Syed Ali, Alekhya Ponduri Lakshmi, J. B, B. Das","doi":"10.4103/2221-6189.374310","DOIUrl":"https://doi.org/10.4103/2221-6189.374310","url":null,"abstract":"","PeriodicalId":45984,"journal":{"name":"Journal of Acute Disease","volume":"1 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70255431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of simulation-based learning regarding management of post-COVID complications in terms of knowledge, clinical decision-making ability, and self-efficacy among nursing students: A quasi-experimental study 基于模拟学习的护生新冠肺炎后并发症管理知识、临床决策能力和自我效能感的有效性:一项准实验研究
IF 0.5 Q4 CRITICAL CARE MEDICINE Pub Date : 2023-01-01 DOI: 10.4103/2221-6189.379276
S. Pareek, Thakur Malvika, ,. Eenu, K. Yogesh, Sarin Jyoti, Nitesh Kumawat
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引用次数: 0
Emerging peril of post–dengue mucormycosis: A case report 登革后毛霉病新出现的危险:一例报告
IF 0.5 Q4 CRITICAL CARE MEDICINE Pub Date : 2023-01-01 DOI: 10.4103/2221-6189.369077
N. Verma, N. Gupta, Vashi Gupta, Smita Nath
Rationale: Dengue fever is a leading cause of death in tropical and subtropical countries. Although most patients have a self-limited febrile illness, the viral infection can induce virus-mediated host changes, making immunocompetent persons susceptible to deadly fungal infections. However, there are only a few reports of such an association. Here we present a case of this deadly co-infection. Patient’s Concern: A 17-year-old male patient was diagnosed with dengue fever. He presented to us with facial swelling, periorbital edema, and black discoloration over the palate during the second week of his illness. Diagnosis: Diagnostic tests confirmed the presence of fungal hyphae. A diagnosis of post-dengue mucormycosis was made. No other comorbidity or underlying immune deficit was detected. Interventions: The patient underwent surgical debridement and antifungal treatment. Outcomes: The patient recovered and showed signs of palatal healing with an advancing mucosal edge. Lessons: Dengue virus and mucor co-infection has brought to light a new pathogenic paradigm. Clinicians need to be aware of this emerging medical condition and maintain a high index of suspicion for mucor co-infections while treating dengue patients.
理由:登革热是热带和亚热带国家的主要死亡原因。虽然大多数患者有自限性发热性疾病,但病毒感染可诱导病毒介导的宿主改变,使免疫正常的人容易受到致命的真菌感染。然而,关于这种关联的报道很少。在这里,我们提出一个致命的合并感染病例。患者关注:一名17岁男性患者被诊断患有登革热。他在发病的第二周向我们表现为面部肿胀、眶周水肿和上颚黑色变色。诊断:诊断试验证实存在真菌菌丝。诊断为登革后毛霉病。未发现其他合并症或潜在的免疫缺陷。干预措施:患者接受手术清创和抗真菌治疗。结果:患者恢复并表现出腭部愈合的迹象,粘膜边缘向前发展。经验教训:登革病毒和毛杆菌合并感染揭示了一种新的致病模式。临床医生需要意识到这种新出现的医疗状况,并在治疗登革热患者时保持对毛杆菌合并感染的高度怀疑。
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引用次数: 0
Impact of COVID-19 pandemic on health-promoting lifestyle behaviors: A cross-sectional study 新冠肺炎大流行对促进健康的生活方式行为的影响:一项横断面研究
IF 0.5 Q4 CRITICAL CARE MEDICINE Pub Date : 2023-01-01 DOI: 10.4103/2221-6189.369073
Ç. Tekin, Züleyha Kılıç
Objective: To explore health-improving behaviors during COVID-19 pandemic and to reveal the impact of the risk perception of COVID-19 on these behaviors. Methods: We recruited a total of 510 participants for this cross-sectional study. The data were collected online using a questionnaire booklet covering a form inquiring about the participants’ demographic, physical, and mental characteristics, the Generalized Anxiety Disorder-7 Scale, and the COVID-19 Perceived Risk Scale. Results: The mean age of the participants was (28.7±10.1) years, and 76.1% were females. Of the participants, 31.8% were overweight and obese. While 35.1% experienced negative alterations in their dietary patterns, 23.9% reported positive changes to their diet during the pandemic. Besides, 47.8% reported their sleep to be negatively affected during the pandemic. While the rate of those with extended screen time was 72.5%, it was 44.3% for the participants engaging in regular exercise. More than one-third of the participants (35.9%) had high and severe anxiety. We also found increased risk perception of COVID-19 among females, obese, those with disturbed eating and sleep quality, healthcare workers, and those with severe anxiety. Conclusions: Overall, the pandemic has appeared to have brought both positive and negative impacts on maintaining and improving eating, sleep, physical activity, and mental health.
目的:探讨新冠肺炎大流行期间的健康改善行为,并揭示新冠肺炎风险认知对这些行为的影响。方法:我们共招募了510名参与者进行横断面研究。数据是通过一份问卷小册子在线收集的,其中包括一份表格,询问参与者的人口统计、身体和心理特征、广泛性焦虑障碍-7量表和COVID-19感知风险量表。结果:参与者平均年龄为(28.7±10.1)岁,女性占76.1%。在参与者中,31.8%的人超重和肥胖。35.1%的人的饮食模式发生了负面变化,23.9%的人报告在大流行期间饮食发生了积极变化。此外,47.8%的人报告说,他们的睡眠在疫情期间受到了负面影响。长时间看屏幕的比例为72.5%,而定期锻炼的比例为44.3%。超过三分之一的参与者(35.9%)有高度和严重的焦虑。我们还发现,女性、肥胖者、饮食和睡眠质量紊乱者、卫生保健工作者和严重焦虑症患者对COVID-19的风险认知增加。结论:总体而言,大流行似乎对维持和改善饮食、睡眠、身体活动和心理健康带来了积极和消极的影响。
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引用次数: 1
Are scorpion stings the new public health threat for southeast Turkey and northern Syria after the earthquakes? An emphasis on Leiurus quinquestriatus 地震后,蝎子蜇伤是土耳其东南部和叙利亚北部新的公共卫生威胁吗?强调了雷乌斯的观点
Q4 CRITICAL CARE MEDICINE Pub Date : 2023-01-01 DOI: 10.4103/2221-6189.385678
Mehmet Uçar
In tropical countries, scorpion sting is a significant cause of disease, leading to severe localized cutaneous reactions, neurologic impairments, and respiratory distress, as well as myocarditis[1]. The world's most poisonous scorpion species, Leiurus quinquestriatus, is found in southern Turkey and is a threat to the public's health in all of the provinces, particularly in Adiyaman and its surrounding areas, which were hit by the recent Turkey and Syria earthquake[1]. The scorpion species Leiurus quinquestriatus is unique to that region. As one of the world's most poisonous scorpions and one of the two dangerous scorpion species found in Turkey, its sting is fatal to people as its venom is twice as potent as that of the other dangerous species, such as Androctonus crassicauda[2]. The most concerning consequences of scorpion sting, pulmonary edema, and cardiogenic shock, are linked to cardiac involvement[3]. An antidote should be given in extreme situations, especially when children are involved. Children under 5 are among the most vulnerable populations associated with a higher risk for these illnesses, which is strongly associated with mortality and poor outcomes[4]. The devastating earthquake hammered southern Turkey and northern Syria on February 6, 2023, resulting in a severe humanitarian disaster. By March 20, 2023, there had been over 50000 reported deaths in Turkey and over 8000 in Syria[5]. The earthquake had forced Syria, which is already at war, and Turkey, which is already in an economic crisis and had been severely struck, into even worse situations. The inhabitants of these two countries would experience pernicious, long-term health consequences if this immediate catastrophe is not appropriately managed. People must adapt to new living situations as a result of disasters like earthquakes. The vast majority of those impacted by the earthquake in Turkey and Syria had left their homes. In addition to being susceptible to the risk of potential outbreaks of post-disaster infectious diseases, the individuals who still reside in earthquake-affected areas do so in tents and containers, exposing them to the outdoor environment and making them prone to insect bites. Most importantly, scorpion stings had been detected in Turkey and Syria, in areas where the earthquake inflicted the most damage[6]. The connection between the earthquake and cases of scorpion stings had not been reported yet since the earthquake took place in the winter. However, it is highly possible that as the weather gets warmer, the movement of stinging poisonous creatures will increase, making the locals a potential target of the risk[7]. In addition to using social and individual methods, policymakers have a lot of work to do to control the scorpion species Leiurus quinquestriatus. In this scenario, it is important to make appropriate use of primary healthcare services and to run efficient prevention and treatment programs to mitigate people's risk from scorpion stings[8].
在热带国家,蝎子蜇伤是引起疾病的重要原因,可导致严重的局部皮肤反应、神经损伤、呼吸窘迫以及心肌炎[1]。世界上最毒的蝎子种类,Leiurus quinquestriatus,在土耳其南部被发现,对所有省份的公众健康构成威胁,特别是在最近遭受土耳其和叙利亚地震袭击的Adiyaman及其周边地区[1]。蝎子是该地区独有的物种。它是世界上最毒的蝎子之一,也是在土耳其发现的两种危险蝎子之一,它的毒液是其他危险物种(如Androctonus crassicauda)的两倍,对人来说是致命的[2]。蝎子蜇伤最令人担忧的后果是肺水肿和心源性休克,这些都与心脏受累有关[3]。在极端情况下,特别是涉及儿童时,应给予解毒剂。5岁以下儿童是最脆弱的人群之一,患这些疾病的风险较高,这与死亡率和不良预后密切相关[4]。2023年2月6日,土耳其南部和叙利亚北部发生特大地震,造成严重的人道主义灾难。截至2023年3月20日,土耳其报告的死亡人数超过5万人,叙利亚报告的死亡人数超过8000人[5]。地震使已经处于战争状态的叙利亚和已经陷入经济危机并受到严重打击的土耳其陷入了更糟糕的境地。如果这一迫在眉睫的灾难得不到适当管理,这两个国家的居民将经历有害的长期健康后果。由于地震等灾害,人们必须适应新的生活环境。受到土耳其和叙利亚地震影响的绝大多数人已经离开了家园。除了容易受到潜在的灾后传染病爆发的风险外,仍然居住在地震灾区的人住在帐篷和集装箱里,使他们暴露在室外环境中,容易被昆虫叮咬。最重要的是,在地震造成最严重破坏的土耳其和叙利亚发现了蝎子蜇伤[6]。由于地震发生在冬季,地震与蝎子蜇伤之间的联系尚未报道。然而,很有可能随着天气变暖,有刺的有毒生物的活动会增加,使当地人成为潜在的风险目标[7]。除了使用社会和个体方法外,决策者还有很多工作要做,以控制quinquestriatus的种类。在这种情况下,重要的是适当利用初级卫生保健服务,并实施有效的预防和治疗方案,以减轻人们被蝎子蜇伤的风险[8]。利益冲突声明作者报告无利益冲突。本研究未获得校外资助。《华尔街日报》的出版商对已出版地图的管辖权要求和机构关系保持中立。
{"title":"Are scorpion stings the new public health threat for southeast Turkey and northern Syria after the earthquakes? An emphasis on <i>Leiurus quinquestriatus</i>","authors":"Mehmet Uçar","doi":"10.4103/2221-6189.385678","DOIUrl":"https://doi.org/10.4103/2221-6189.385678","url":null,"abstract":"In tropical countries, scorpion sting is a significant cause of disease, leading to severe localized cutaneous reactions, neurologic impairments, and respiratory distress, as well as myocarditis[1]. The world's most poisonous scorpion species, Leiurus quinquestriatus, is found in southern Turkey and is a threat to the public's health in all of the provinces, particularly in Adiyaman and its surrounding areas, which were hit by the recent Turkey and Syria earthquake[1]. The scorpion species Leiurus quinquestriatus is unique to that region. As one of the world's most poisonous scorpions and one of the two dangerous scorpion species found in Turkey, its sting is fatal to people as its venom is twice as potent as that of the other dangerous species, such as Androctonus crassicauda[2]. The most concerning consequences of scorpion sting, pulmonary edema, and cardiogenic shock, are linked to cardiac involvement[3]. An antidote should be given in extreme situations, especially when children are involved. Children under 5 are among the most vulnerable populations associated with a higher risk for these illnesses, which is strongly associated with mortality and poor outcomes[4]. The devastating earthquake hammered southern Turkey and northern Syria on February 6, 2023, resulting in a severe humanitarian disaster. By March 20, 2023, there had been over 50000 reported deaths in Turkey and over 8000 in Syria[5]. The earthquake had forced Syria, which is already at war, and Turkey, which is already in an economic crisis and had been severely struck, into even worse situations. The inhabitants of these two countries would experience pernicious, long-term health consequences if this immediate catastrophe is not appropriately managed. People must adapt to new living situations as a result of disasters like earthquakes. The vast majority of those impacted by the earthquake in Turkey and Syria had left their homes. In addition to being susceptible to the risk of potential outbreaks of post-disaster infectious diseases, the individuals who still reside in earthquake-affected areas do so in tents and containers, exposing them to the outdoor environment and making them prone to insect bites. Most importantly, scorpion stings had been detected in Turkey and Syria, in areas where the earthquake inflicted the most damage[6]. The connection between the earthquake and cases of scorpion stings had not been reported yet since the earthquake took place in the winter. However, it is highly possible that as the weather gets warmer, the movement of stinging poisonous creatures will increase, making the locals a potential target of the risk[7]. In addition to using social and individual methods, policymakers have a lot of work to do to control the scorpion species Leiurus quinquestriatus. In this scenario, it is important to make appropriate use of primary healthcare services and to run efficient prevention and treatment programs to mitigate people's risk from scorpion stings[8].","PeriodicalId":45984,"journal":{"name":"Journal of Acute Disease","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135799470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Central venous catheterization-related complications in a cohort of 100 hospitalized patients: An observational study 100例住院患者中心静脉置管相关并发症的观察性研究
Q4 CRITICAL CARE MEDICINE Pub Date : 2023-01-01 DOI: 10.4103/2221-6189.385685
Reena Singh, Naimish Patel, Nidhi Mehta, Gaurav Singh, Nirav Patel
Objective: To evaluate the complications of central venous catheterization (CVC). Methods: A prospective, observational study was conducted at a tertiary care center in India from December 2018 to September 2020. Critically ill patients (aged ≥18 years) in the intensive care unit undergoing CVC procedures were included in the study. Baseline demographics and detailed medical history were recorded. Chest X-rays and electrocardiography were performed on all the patients. Complications associated with CVC were recorded. Results: A total of 100 patients with the indication for centralvenous catheter insertion were included. The majority (81%) of the patients were inserted with CVC at the right internal jugular vein. Complications such as arterial puncture (2%), hematoma (4%), blood clot formation (4%), catheter kinking (3%), thoracic injury(1%), thrombophlebitis (6%), sepsis (9%) and nerve injury (1%)were reported. Conclusions: Though central venous access is preferred in management of critically ill patients, it has its risks. However, early recognition and prompt management of complications may reduce mortality and morbidity. Physicians and intensive care unit intensivists should be vigilant for central venous catheter-related complications. Suitable site selection, operator experience, and proper catheter maintenance are associated with optimal outcomes.
目的:探讨中心静脉置管术的并发症。方法:2018年12月至2020年9月,在印度一家三级医疗中心进行了一项前瞻性观察性研究。在重症监护室接受CVC手术的危重患者(年龄≥18岁)被纳入研究。记录基线人口统计和详细的病史。所有患者均行胸片和心电图检查。记录CVC相关并发症。结果:共纳入100例符合中心静脉置管指征的患者。大多数(81%)患者在右颈内静脉置入CVC。并发症如动脉穿刺(2%)、血肿(4%)、血栓形成(4%)、导管扭结(3%)、胸腔损伤(1%)、血栓性静脉炎(6%)、脓毒症(9%)和神经损伤(1%)。结论:中心静脉通路是危重病人的首选途径,但也存在一定的风险。然而,早期发现和及时处理并发症可以降低死亡率和发病率。内科医生和重症监护病房的重症医师应警惕中心静脉导管相关的并发症。合适的位置选择、操作人员经验和适当的导管维护与最佳结果相关。
{"title":"Central venous catheterization-related complications in a cohort of 100 hospitalized patients: An observational study","authors":"Reena Singh, Naimish Patel, Nidhi Mehta, Gaurav Singh, Nirav Patel","doi":"10.4103/2221-6189.385685","DOIUrl":"https://doi.org/10.4103/2221-6189.385685","url":null,"abstract":"Objective: To evaluate the complications of central venous catheterization (CVC). Methods: A prospective, observational study was conducted at a tertiary care center in India from December 2018 to September 2020. Critically ill patients (aged ≥18 years) in the intensive care unit undergoing CVC procedures were included in the study. Baseline demographics and detailed medical history were recorded. Chest X-rays and electrocardiography were performed on all the patients. Complications associated with CVC were recorded. Results: A total of 100 patients with the indication for centralvenous catheter insertion were included. The majority (81%) of the patients were inserted with CVC at the right internal jugular vein. Complications such as arterial puncture (2%), hematoma (4%), blood clot formation (4%), catheter kinking (3%), thoracic injury(1%), thrombophlebitis (6%), sepsis (9%) and nerve injury (1%)were reported. Conclusions: Though central venous access is preferred in management of critically ill patients, it has its risks. However, early recognition and prompt management of complications may reduce mortality and morbidity. Physicians and intensive care unit intensivists should be vigilant for central venous catheter-related complications. Suitable site selection, operator experience, and proper catheter maintenance are associated with optimal outcomes.","PeriodicalId":45984,"journal":{"name":"Journal of Acute Disease","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135799614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The modified systemic inflammation score is a predictor of ICU admission of COVID-19 patients 改良全身炎症评分是新冠肺炎患者入住ICU的预测指标
IF 0.5 Q4 CRITICAL CARE MEDICINE Pub Date : 2023-01-01 DOI: 10.4103/2221-6189.369074
Damla Anbarlı Metin, Hamdi Metin, Ş. Atiş
Objective: To evaluate the effect of the modified systemic inflammation score (mSIS) on prognosis in patients diagnosed with COVID-19. Methods: In this retrospective cross-sectional study, 181 patients were selected and divided into two groups: patients with and without admission to the intensive care unit (ICU). An albumin level of ≥4.0 g/dL and lymphocyte-to-monocyte ratio (LMR) of ≥3.4 was scored 0, an albumin level of <4.0 g/dL or LMR of <3.4 was scored 1, and an albumin level of <4.0 g/dL and LMR of <3.4 was scored 2. Results: A total of 242 COVID-19 positive patients were initially included in this study. Of these patients, 61 were excluded and 181 patients remained. Among the 181 participants, 94 (51.9%) were female, and the median age was 61 (51, 75) years. The mSIS scale ranged from 0 to 2. After analysis, the median score was 0 (0, 0) in the non-ICU group and 2 (0, 2) in the ICU group (P<0.001). The median white blood cell, lymphocyte counts, and albumin levels were lower in the ICU group (P<0.001, P<0.001, and P<0.001, respectively). In logistic regression analysis lymphocytopenia (OR=5.158, 95% CI=1.249-21.304, P=0.023), hypoalbuminemia (OR=49.921, 95% CI=1.843-1 352.114, P=0.020), AST elevation (OR=3.939, 95% CI=1.017-15.261, P=0.047), and mSIS=2 (OR=5.853, 95% CI=1.338-25.604, P=0.019) were identified as independent predictors of ICU admission. Conclusion: The mSIS can be used as an independent parameter for establishing the intensive care needs of patients with COVID-19.
目的:探讨改良全身炎症评分(mSIS)对新冠肺炎患者预后的影响。方法:采用回顾性横断面研究方法,将181例患者分为重症监护病房(ICU)住院患者和非ICU住院患者两组。白蛋白水平≥4.0 g/dL、LMR≥3.4评分为0,白蛋白水平<4.0 g/dL、LMR <3.4评分为1,白蛋白水平<4.0 g/dL、LMR <3.4评分为2。结果:共纳入242例COVID-19阳性患者。在这些患者中,61例被排除,181例被保留。181例受试者中,女性94例(51.9%),中位年龄61岁(51,75)岁。mSIS评分范围从0到2。经分析,非ICU组中位评分为0 (0,0),ICU组中位评分为2(0,2),差异有统计学意义(P<0.001)。ICU组中位白细胞、淋巴细胞计数、白蛋白水平均较低(P<0.001、P<0.001、P<0.001)。在logistic回归分析中,淋巴细胞减少症(OR=5.158, 95% CI=1.249 ~ 21.304, P=0.023)、低白蛋白血症(OR=49.921, 95% CI=1.843 ~ 352.114, P=0.020)、AST升高(OR=3.939, 95% CI=1.017 ~ 15.261, P=0.047)和mSIS=2 (OR=5.853, 95% CI=1.338 ~ 25.604, P=0.019)被确定为ICU入院的独立预测因素。结论:mSIS可作为确定COVID-19患者重症监护需求的独立参数。
{"title":"The modified systemic inflammation score is a predictor of ICU admission of COVID-19 patients","authors":"Damla Anbarlı Metin, Hamdi Metin, Ş. Atiş","doi":"10.4103/2221-6189.369074","DOIUrl":"https://doi.org/10.4103/2221-6189.369074","url":null,"abstract":"Objective: To evaluate the effect of the modified systemic inflammation score (mSIS) on prognosis in patients diagnosed with COVID-19. Methods: In this retrospective cross-sectional study, 181 patients were selected and divided into two groups: patients with and without admission to the intensive care unit (ICU). An albumin level of ≥4.0 g/dL and lymphocyte-to-monocyte ratio (LMR) of ≥3.4 was scored 0, an albumin level of <4.0 g/dL or LMR of <3.4 was scored 1, and an albumin level of <4.0 g/dL and LMR of <3.4 was scored 2. Results: A total of 242 COVID-19 positive patients were initially included in this study. Of these patients, 61 were excluded and 181 patients remained. Among the 181 participants, 94 (51.9%) were female, and the median age was 61 (51, 75) years. The mSIS scale ranged from 0 to 2. After analysis, the median score was 0 (0, 0) in the non-ICU group and 2 (0, 2) in the ICU group (P<0.001). The median white blood cell, lymphocyte counts, and albumin levels were lower in the ICU group (P<0.001, P<0.001, and P<0.001, respectively). In logistic regression analysis lymphocytopenia (OR=5.158, 95% CI=1.249-21.304, P=0.023), hypoalbuminemia (OR=49.921, 95% CI=1.843-1 352.114, P=0.020), AST elevation (OR=3.939, 95% CI=1.017-15.261, P=0.047), and mSIS=2 (OR=5.853, 95% CI=1.338-25.604, P=0.019) were identified as independent predictors of ICU admission. Conclusion: The mSIS can be used as an independent parameter for establishing the intensive care needs of patients with COVID-19.","PeriodicalId":45984,"journal":{"name":"Journal of Acute Disease","volume":"12 1","pages":"18 - 22"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45304973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Journal of Acute Disease
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