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Current role of open surgery in adrenal tumors. 开放手术在肾上腺肿瘤中的作用。
IF 0.6 Q4 SURGERY Pub Date : 2020-01-01
A Chiappini, G Frattolillo, G Paradiso, A De Gori, V Scarano Catanazaro, R Avantifiori, E Fiori, G De Toma

Aim: The aim of this retrospective evaluation is to assess the current role of open adrenalectomy, in particular in cases of adrenocortical carcinoma (ACC).

Materials and methods: From January 2009 to May 2019, 26 open out of 233 adrenalectomies were performed in our Academic Department. Open adrenalectomy was performed by the anterior approach. A midline abdominal incision or a subcostal surgical incision was used to reach the peritoneal cavity. The resection was defined R0 if the margins of the sample were negative for malignancy.

Results: Open adrenalectomy was performed in 26 patients: 10 men and 16 women with a mean age of 61±25.3 years and a mean BMI of 28.4±2.9. The right adrenal gland was removed in 15 cases Romaand the left in 11 cases.We reported 18 diagnosis of malignant pathology. The other diagnosis concerned 5 cases of pheochromocytoma, 1 case of Cushing's disease and 2 cases of hyperaldosteronism. Mean tumor size was 7.7±5.5. Mean operative time was 160 min (range=110-205 minutes). Mean postoperative stay was 7±2 days. Only 3 (10%) patient showed postoperative grade II complications, according to Clavien-Dindo classification. Midline abdominal incision was used in 18 patients, subcostalsurgical incision in 5 patients and bilateral subcostal surgical incision in 3 patients. 3 right nephrectomy was necessary to remove the entire tumor mass. An en bloc R0 tumor resection was accomplished in all cases.There was no intra and perioperative mortality. All patients recovered well from surgery. The mean follow-up period was 15 (range=6-48) months.

Conclusion: In conclusion, our retrospective study points out the role of open adrenalectomy as the treatment of choice in selected cases with known or suspected malignant adrenal tumors and with size greater than 12 cm.

目的:本回顾性评价的目的是评估目前开放肾上腺切除术的作用,特别是在肾上腺皮质癌(ACC)的情况下。材料与方法:2009年1月至2019年5月,我院学术部共进行了233例肾上腺切除术,其中26例为开腹手术。经前路行开放肾上腺切除术。采用腹中线切口或肋下切口到达腹膜腔。如果样本边缘的恶性肿瘤呈阴性,则切除定义为R0。结果:26例患者行开放肾上腺切除术,男10例,女16例,平均年龄61±25.3岁,平均BMI 28.4±2.9。右肾上腺切除15例,左肾上腺切除11例。我们报告了18例恶性病理诊断。另外5例为嗜铬细胞瘤,1例为库欣病,2例为高醛固酮增多症。平均肿瘤大小为7.7±5.5。平均手术时间160 min(范围110 ~ 205 min)。术后平均住院时间为7±2天。根据Clavien-Dindo分级,仅有3例(10%)患者出现术后II级并发症。腹部中线切口18例,肋下切口5例,双侧肋下切口3例。需行右肾切除术以切除整个肿瘤。所有病例均完成整体R0肿瘤切除术。术中及围手术期均无死亡。所有患者术后恢复良好。平均随访15个月(范围6 ~ 48个月)。结论:我们的回顾性研究指出,对于已知或疑似恶性肾上腺肿瘤且体积大于12cm的患者,开放性肾上腺切除术是首选的治疗方法。
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引用次数: 0
Minilaparotomic incision for haemorrhagic corpus luteum: a case report. 剖腹小切口治疗黄体出血1例。
IF 0.6 Q4 SURGERY Pub Date : 2020-01-01
V Leanza, C Mininni, F M Di Grazia, F Genovese, A Carbonaro, G Leanza, M Palumbo

Corpus luteum cyst rupture with consequent hemoperitoneum is a common cause of admission to the emergency room. This condition is frequently misdiagnosed because of overlapping of clinical findings in acute gynecologic diseases. However, an incorrect identification may lead to delay in surgical treatment, which can Romabe a life-threatening condition. Ultrasound (US) is the first technique used for diagnosis that can confirm or dismiss the presence of intraperitoneal fluid. Secondly, the contrast-enhanced computed tomography (CT) is the quickest way to identify the site of active bleeding and to establish the correct management of the clinical condition. Herein, we report a case of a 19-years-old girl with acute abdominal pain correctly identified by diagnostic images and treated with mini-invasive surgery techniques in order to quickly act without clinic and aesthetic sequelae.

黄体囊肿破裂,随之而来的腹膜出血是入院急诊室的常见原因。由于急性妇科疾病的临床表现重叠,这种情况经常被误诊。然而,错误的识别可能会导致手术治疗的延误,这可能会危及生命。超声(US)是用于诊断的第一种技术,可以确认或排除腹腔内液体的存在。其次,对比增强计算机断层扫描(CT)是识别活动性出血部位和建立正确的临床状况管理的最快方法。在此,我们报告一个19岁的女孩急性腹痛的病例,通过诊断图像正确识别,并采用微创手术技术治疗,以迅速采取行动,没有临床和美学后遗症。
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引用次数: 0
Diagnostic and therapeutic role of laparoscopy in perforated peptic ulcer in the elderly patients. 腹腔镜在老年穿孔性消化性溃疡中的诊断和治疗作用。
IF 0.6 Q4 SURGERY Pub Date : 2020-01-01
Angela Giordano, P Prosperi, G Alemanno, C Bergamini, A Bruscino, A Valeri

Aim: The purpose of this study is to analyze the outcome of elderly patients with perforated peptic ulcer comparing laparoscopic treatment versus open approach.

Methods: In our General and Emergency Surgery Unit in the last 3 years, 20 elderly patients with perforated peptic ulcer were performed. We considered elderly all patients over the age of 65 years (10 females and 10 males; the mean age was 75 years). 16 patients (80%) were submitted to laparoscopic repair with omentoplasty and 4 (20%) to open repair. The patients were classified using the Boye's score which influenced the choice of surgical treatment and the outcoEmergency Romame. The two groups were compared in terms of operative surgery times, complication rate, mortality and postoperative outcomes.

Discussion: Perforated peptic ulcer is a common abdominal disease that is treated by surgery. The potential advantages of laparoscopy, both in terms of diagnosis and therapy, are clear and the major advantages may be observed in cases with peritonitis secondary as a perforated peptic ulcer where laparoscopy allows the confirmation of the diagnosis, the identification of the position of the ulcer and the repair. With the age the risks of comorbidities increases multidisease syndrome. Elderly patients suffer from frailty syndrome. All these factors make the elderly patient a major challenge for a laparoscopy treatment.

Conclusion: The laparoscopic approach is an effective method for treatment of perforated peptic ulcer in the elderly with a great diagnostic and therapeutic role. Nowadays more prospective randomized studies are needed to evaluate the effectiveness of laparoscopic versus open repair.

目的:本研究的目的是分析老年消化性溃疡穿孔患者的结果,比较腹腔镜治疗与开放方法。方法:近3年来,我院普通外科及急诊外科共收治20例老年消化性溃疡穿孔患者。我们考虑了年龄在65岁以上的所有患者(10名女性和10名男性;平均年龄为75岁)。16例(80%)采用腹腔镜网膜成形术修复,4例(20%)采用开放式修复。使用Boye评分对患者进行分类,该评分影响手术治疗的选择和结果。比较两组手术次数、并发症发生率、死亡率及术后预后。讨论:穿孔性消化性溃疡是一种常见的腹部疾病,可通过手术治疗。腹腔镜在诊断和治疗方面的潜在优势是明确的,主要优势可以在继发性腹膜炎作为穿孔性消化性溃疡的病例中观察到,腹腔镜可以确认诊断,确定溃疡的位置和修复。随着年龄的增长,合并多病综合征的风险增加。老年病人患有虚弱综合症。所有这些因素使老年患者成为腹腔镜治疗的主要挑战。结论:腹腔镜入路是治疗老年人穿孔性消化性溃疡的有效方法,具有重要的诊断和治疗作用。目前需要更多的前瞻性随机研究来评估腹腔镜与开放式修复的有效性。
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引用次数: 0
The evolution of robotic arm-assisted arthroplasty in Greece. 希腊机械臂辅助关节成形术的发展。
IF 0.6 Q4 SURGERY Pub Date : 2020-01-01
C Koutserimpas, K Dretakis

Background: The robotic arm-assisted (Mako) arthroplasty was introduced in Greece in January 2014, through the years of financial crisis. The purpose of this study is to demonstrate its evolution per procedure throughout the years.

Materials and methods: Data regarding type of procedure: partial knee arthroplasty (PKA), total knee arthroplasty (TKA) and total hip arthroplasty (THA) were collected from the official distributor of the Mako platform in Greece. The number of Mako arthroplasties were calculated annually and monthly per procedure type from January 2014 to December 2018.

Results: A total of 1081 robotic arm-assisted arthroplasties have been performed in Greece in two private hospitals. Mako cases showed overall 163.06% increase, while THA showed 235.1% increase, during the study period. On the other hand PKA showed 61% decrease, while in during one year (2017-2018) TKA showed 402% increase.

Conclusions: Introducing robots into the orthopedic operating theater may improve precision, could lead to lower complication rates and finally may offer higher patient satisfaction scores. However, the total growth of robotic arm-assisted arthroplasties in Greece should be interpreted with caution, since all surgeries were performed in private institutions and, therefore, the economic burden of these procedures may have been withstood by specific social class patients.

背景:经历了多年的金融危机,2014年1月,希腊引入了机械臂辅助(Mako)关节成形术。本研究的目的是展示其演变的每一个程序,在多年来。材料和方法:关于手术类型的数据:部分膝关节置换术(PKA),全膝关节置换术(TKA)和全髋关节置换术(THA)从希腊Mako平台的官方分销商收集。2014年1月至2018年12月,每年和每月计算每种手术类型的Mako关节置换术的数量。结果:希腊两家私立医院共实施机械臂辅助关节置换术1081例。研究期间,灰鲭鱼病例总数增加163.06%,THA病例总数增加235.1%。另一方面,PKA下降了61%,而在一年内(2017-2018),TKA增长了402%。结论:机器人进入骨科手术室可提高手术精度,降低并发症发生率,提高患者满意度。然而,希腊机械臂辅助关节置换术的总体增长应该谨慎解读,因为所有手术都是在私人机构进行的,因此,这些手术的经济负担可能是由特定社会阶层的患者承受的。
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引用次数: 0
Spontaneous transdiaphragmatic intercostal hernia: clinical considerations and management. 自发性经膈肋间疝:临床考虑和处理。
IF 0.6 Q4 SURGERY Pub Date : 2020-01-01
M T Lonardo, F Frezzotti, M Collalti, A Natili, A Metere

Most diaphragmatic ruptures are due to the traumatic or penetrating injury, while the spontaneous diaphragmatic rupture is considered uncommon. The spontaneous transdiaphragmatic hernia is a consequence of violent coughing, vomiting that increase the thoracoabdominal pressure causing the diaphragmatic rupture. Even rarer is the concomitant prolapse of abdominal viscera into the thoracic subcutis through the chest wall, a condition known as spontaneous transdiaphragmatic intercostal hernia. Herein, we present a rare case of spontaneous transdiaphragmatic intercostal hernia presenting as a thoracoabdominal emergency.

大多数膈破裂是由于外伤性或穿透性损伤,而自发性膈破裂被认为是罕见的。自发性横膈膜疝是剧烈咳嗽、呕吐增加胸腹压力导致横膈膜破裂的结果。更罕见的是腹部脏器通过胸壁脱垂到胸皮下,这种情况被称为自发性经膈肋间疝。在此,我们提出一个罕见的自发性经膈肋间疝的情况下,表现为胸腹急症。
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引用次数: 0
Laparoscopic Roux-en-Y gastric bypass in the treatment of obesity: evidence based update through randomized clinical trials and meta-analyses. 腹腔镜Roux-en-Y胃旁路治疗肥胖:随机临床试验和荟萃分析的循证更新
IF 0.6 Q4 SURGERY Pub Date : 2020-01-01
J Morales-Maza, J H Rodriguez-Quintero, G E Sanchez-Morales, E Sanchez Garcia-Ramos, G Romero-Velez, J L Aguilar-Frasco, A S Pimienta-Ibarra, F E Alvarez-Bautista, P Leon, J D Hernandez-Acevedo, G Del Angel-Millan, M Sierra

Bariatric surgery was introduced in 1953, but during the last 20 years its popularity has increased after the development of significant Romaevidenced based breakthroughs in the field. Currently, approximately 150 long-term randomized clinical trials and 40 meta-analyses support and give credibility to the surgical approaches for the treatment of obesity and its related metabolic disturbances. Bariatric surgery has demonstrated improved outcomes compared to medical treatment, conduct therapy, and endoscopic procedures. Roux-en-Y gastrojejunostomy (RYGB) and Sleeve gastrectomy (SG) are the surgical procedures most frequently performed, due to their satisfactory results and security profile. There is sufficient evidence in medical literature to perform these procedures when indicated; however, there are still several controversies regarding technical aspects that need to be further explored.

减肥手术于1953年推出,但在过去的20年里,随着该领域的重大突破的发展,它的受欢迎程度有所增加。目前,大约有150项长期随机临床试验和40项荟萃分析支持并给予手术方法治疗肥胖及其相关代谢紊乱的可信度。与药物治疗、传导疗法和内窥镜手术相比,减肥手术已证明改善了结果。Roux-en-Y胃空肠吻合术(RYGB)和袖胃切除术(SG)是最常用的外科手术,因为它们的效果令人满意和安全性。医学文献中有足够的证据表明,在需要时可以进行这些手术;然而,在技术方面仍然存在一些争议,需要进一步探讨。
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引用次数: 0
Retroperitoneal sarcomas: from diagnosis to treatment. Case series and review of the literature. 腹膜后肉瘤:从诊断到治疗。个案系列及文献回顾。
IF 0.6 Q4 SURGERY Pub Date : 2020-01-01
D Mantas, N Garmpis, D Polychroni, A Garmpi, C Damaskos, A Liakea, G Sypsa, E Kouskos

Background: Retroperitoneal sarcoma is a rare malignancy arising from mesenchymal cells, most commonly presented as an abdominal mass and is associated with poor prognosis. The most effective treatment modality for retroperitoneal sarcomas is complete surgical resection, including sometimes adjacent organs infiltrated by the tumor. Radiotherapy is frequently applied and has shown some benefit, while the role of chemotherapy and molecular-targeted agents is still not clear. Local recurrence is common for retroperitoneal sarcomas and still remains the main cause of death. The major factors associated with the overall survival are tumor grade, histological subtype, complete macroscopic excision and multifocality.

Aim: To report our experience via the presentation of patients with retroperitoneal sarcomas managed in our department during the period 2014-18; and to review the current literature.

Patients and methods: Eight patients appeared with chronic non-specific complaints including abdominal distension and changes in bowel or bladder habit, while one patient presented with acute abdominal pain due to mass rupture. All of the patients underwent surgical resection of the tumor.

Results: Among the patients, seven were operated for primary disease and one only for recurrent. The most common histologic type was liposarcoma (well-differentiated, dedifferentiated), found in five patients; followed by leiomyosarcoma found in two cases. Fibrous histiocytoma was found in only one case. The masses were removed with macroscopically clear margins (R0 and R1 resections) in four cases. In five patient cases adjuvant therapy was required. Three patients are still alive and free of disease.

Conclusions: Retroperitoneal sarcomas present to be a therapeutic challenge based on their location, their extent at the time of diagnosis and the high risk of local recurrence or distant metastasis. Their management requires a multidisciplinary approach, with the surgical resection remaining the mainstay of curative treatment, combined with surveillance for early detection of recurrence or metastases.

背景:腹膜后肉瘤是一种由间充质细胞引起的罕见恶性肿瘤,最常表现为腹部肿块,预后较差。腹膜后肉瘤最有效的治疗方式是完全手术切除,有时包括肿瘤浸润的邻近器官。放疗是常用的治疗方法,并已显示出一定的疗效,而化疗和分子靶向药物的作用仍不清楚。局部复发是常见的腹膜后肉瘤,仍然是死亡的主要原因。与总生存率相关的主要因素是肿瘤分级、组织学亚型、完全肉眼切除和多灶性。目的:通过2014-18年间我科收治的腹膜后肉瘤患者的临床表现,报告我们的经验;并回顾当前的文献。患者与方法:8例患者出现腹胀、排便习惯改变等慢性非特异性主诉,1例患者因肿块破裂出现急性腹痛。所有患者均行手术切除肿瘤。结果:7例因原发疾病行手术,1例因复发疾病行手术。最常见的组织学类型为脂肪肉瘤(高分化、去分化),见于5例患者;其次为平滑肌肉瘤2例。纤维组织细胞瘤仅1例。4例肿块切除,宏观边缘清晰(R0和R1切除)。5例患者需要辅助治疗。三名病人仍然活着,没有疾病。结论:腹膜后肉瘤的位置、诊断时的范围以及局部复发或远处转移的高风险是治疗的挑战。它们的治疗需要多学科的方法,手术切除仍然是治疗的主要方法,并结合早期发现复发或转移的监测。
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引用次数: 0
Systemic immune response after open tension-free inguinal hernia repair under different anesthetic alternatives: a prospective comparative study. 不同麻醉方案下开放式无张力腹股沟疝修补术后的全身免疫反应:一项前瞻性比较研究。
IF 0.6 Q4 SURGERY Pub Date : 2020-01-01
D Symeonidis, A Diamantis, I Baloyiannis, G Tzovaras, K Tepetes

Purpose: The purpose of the present study was a comparison of the systemic inflammatory response intensity through the estimation of C- reactive protein and albumin levels before and after open tension free inguinal hernia repair performed under different anesthetic alternatives.

Patients and methods: Totally, 125 inguinal hernia patients scheduled for unilateral primary open tension free inguinal repair unRomader local (50 patients), spinal (50 patients) and general anesthesia (25 patients) have been included in this prospective study.

Results: The group of local anesthesia was associated with the higher postoperative serum levels of albumin compared to the group of general anesthesia (P 0.013). Local anesthesia was also associated with higher postoperative serum albumin levels compared to regional anesthesia but however the difference was not statistically significant (P 0.282). The group of local anesthesia was also associated with the lower postoperative levels of CRP compared to the regional (P 0.0094) and general anesthesia (P 0.0009) groups.

Conclusion: Local anesthesia proved superior to regional or general anesthesia for open tension free inguinal hernia repair in the given patient sample from the standpoint of the inflammatory and acute phase response.

目的:本研究的目的是通过评估不同麻醉方案下开放式无张力腹股沟疝修补术前后的C反应蛋白和白蛋白水平,比较全身炎症反应强度。患者和方法:本前瞻性研究共纳入125例腹股沟疝患者,计划在romader局部(50例)、脊柱(50例)和全身麻醉(25例)下进行单侧开放式无张力腹股沟修补术。结果:局麻组术后血清白蛋白水平高于全麻组(P < 0.013)。与区域麻醉相比,局部麻醉术后血清白蛋白水平也较高,但差异无统计学意义(P 0.282)。与局部麻醉组(P 0.0094)和全身麻醉组(P 0.0009)相比,局麻组术后CRP水平也较低。结论:从炎症和急性期反应的角度来看,局麻优于区域或全麻,适用于开放式无张力腹股沟疝修补术。
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引用次数: 0
Advances in bioengineering of complex tissues: state of the art of mucosae decellularization protocols. 复杂组织生物工程的进展:粘膜脱细胞技术的现状。
IF 0.6 Q4 SURGERY Pub Date : 2020-01-01
M I Rizzo, C Contardi, M Esposito, M Zama

The loss or deficiency of a tissue or organ is a serious health problem and severely affects the patients' quality of life. In the near future, an option for solving this problem will be the development of bio-derived extracellular matrices (ECM) from huPlastic Romaman or animal tissues and their usage for in vitro or in vivo cellular reseeding. Many researchers are working on this development. Nowadays, different decellularization protocols have been developed to manufacture ECMs but there is not yet a consensus about the most efficient procedures. This review aims to describe the state of the art in the field of decellularization of complex mucosal tissues, analizing and comparing the most recent and most valiant articles published about this procedure.

一个组织或器官的丧失或缺失是一个严重的健康问题,严重影响患者的生活质量。在不久的将来,解决这一问题的一个选择将是从人类或动物组织中开发生物来源的细胞外基质(ECM),并将其用于体外或体内细胞再生。许多研究人员正在研究这一进展。目前,已经开发了不同的脱细胞方案来制造ecm,但尚未就最有效的程序达成共识。这篇综述的目的是描述复杂粘膜组织脱细胞领域的最新技术,分析和比较最近发表的关于这一程序的最优秀的文章。
{"title":"Advances in bioengineering of complex tissues: state of the art of mucosae decellularization protocols.","authors":"M I Rizzo,&nbsp;C Contardi,&nbsp;M Esposito,&nbsp;M Zama","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The loss or deficiency of a tissue or organ is a serious health problem and severely affects the patients' quality of life. In the near future, an option for solving this problem will be the development of bio-derived extracellular matrices (ECM) from huPlastic Romaman or animal tissues and their usage for in vitro or in vivo cellular reseeding. Many researchers are working on this development. Nowadays, different decellularization protocols have been developed to manufacture ECMs but there is not yet a consensus about the most efficient procedures. This review aims to describe the state of the art in the field of decellularization of complex mucosal tissues, analizing and comparing the most recent and most valiant articles published about this procedure.</p>","PeriodicalId":46352,"journal":{"name":"Giornale di Chirurgia","volume":"41 1","pages":"50-65"},"PeriodicalIF":0.6,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37626318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Conservative management of streptococcal necrotizing periorbital fasciitis following primary VZV infection. 原发VZV感染后链球菌坏死性眶周筋膜炎的保守治疗。
IF 0.6 Q4 SURGERY Pub Date : 2020-01-01
E Kontou, G Bontzos, D Triantafyllou, C Garnavou-Xirou, A Ragkousis, T Xirou

A 45-year old male patient, with a past history of illicit drug abuse and hepatitis C, presented with a 2 day history of worsening eyelid edema. Examination of the globe was impossible due to eyelid fusion caused by extensive soft tissue damage. Based on the examination, a diagnosis of necrotic fasciitis secondary to VZV infection was Romamade. The patient received empirical treatment with intravenous acyclovir, meropenem and vancomycin. CT imaging demonstrated no ocular involvement. Lesions were cultivated, revealing presence of Streptococcus pyogenes. Intravenous clindamycin was added to his course. Improvement was gradually observed. The patient received treatment for a total of 21 days, resulting in excellent final outcome. His final visual acuity was 0.9 on a Snellen chart, without signs of ocular inflammation. No surgical intervention was required and lesions fully healed with conservative management. Clinical outcomes depend on prompt treatment initiation, whilst delay in the diagnosis can prove fatal.

45岁男性患者,既往有非法药物滥用史和丙型肝炎,眼睑水肿加重2天。由于广泛的软组织损伤导致眼睑融合,无法对眼球进行检查。根据检查,诊断为继发于VZV感染的坏死性筋膜炎。患者给予静脉注射阿昔洛韦、美罗培南、万古霉素的经验性治疗。CT未见眼部受累。培养病变,发现存在化脓性链球菌。在疗程中加入静脉注射克林霉素。情况逐渐改善。患者共接受治疗21天,最终预后良好。根据斯涅伦视力表,他的最终视力为0.9,没有眼部炎症的迹象。不需要手术干预,病灶在保守治疗下完全愈合。临床结果取决于及时开始治疗,而诊断延误可能是致命的。
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引用次数: 0
期刊
Giornale di Chirurgia
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