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Long-term steroid treatment: a potential risk factor for uterine rupture during pregnancy? 长期类固醇治疗:妊娠期子宫破裂的潜在危险因素?
IF 0.6 Q4 SURGERY Pub Date : 2019-03-01
C Grigoriadis, A Tympa, V Delivoria, S Baka, K Theodoraki

Aim: Uterine rupture during pregnancy is a rare but life threatening event in Obstetrics, with potentially catastrophic consequences for both the fetus and the mother. There are few published case reports that investigate the possible association between long-term steroid treatment and uterine rupture during the antenatal period.

Case report: A 33-year-old G2P1 woman with obstetrical history of one previous transverse low-segment caesarean section presented at the 30th week of gestation with severe abdominal pain which started spontaneously one hour before. She had medical history of pemphigus under long-term treatment with prednisolone. Clinical examination showed acute abdomen while the fetus developed heart rate decelerations. Emergency caesarean section via Pfannenstiel incision under general anaesthesia was performed. Uterine rupture was recognised with localization not at the scar of the previous caesarean section but at the left posterolateral site of the uterine fundus. A healthy premature male infant with an excellent Apgar score and weight of 1510 gr. was delivered by a low-segment caesarean section. Surgical repair of the site of the rupture with isolated sutures followed. There was no need for hysterectomy as hemorrhage was controlled and hemodynamic stability of the woman was restored.

Discussion: Uterine rupture should be included in the differential diagnosis by all obstetricians not only during labour but in acute abdominal pain during the antenatal period as well.

目的:怀孕期间子宫破裂是一种罕见但危及生命的产科事件,对胎儿和母亲都有潜在的灾难性后果。很少有已发表的病例报告调查长期类固醇治疗和产前子宫破裂之间可能存在的联系。病例报告:一名33岁G2P1女性,既往有一次横断低段剖宫产的产科史,于妊娠第30周出现严重腹痛,1小时前自发开始。患者有天疱疮病史,长期使用强的松龙治疗。临床检查显示急腹症,胎儿心率减慢。全麻下经Pfannenstiel切口行紧急剖宫产术。子宫破裂被认为不是定位在以前剖腹产的疤痕,而是在子宫底的左后外侧。我们采用低节段剖宫产术接生了一名Apgar评分优良、体重1510克的健康早产男婴。随后手术修复破裂部位并进行隔离缝合。由于出血得到控制,血流动力学稳定性得到恢复,不需要切除子宫。讨论:子宫破裂应包括在鉴别诊断的所有产科医生不仅在分娩,而且在产前急性腹痛以及。
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引用次数: 0
Effectiveness of a preventive bundle of measures for reducing surgical site infections in patients undergoing elective orthopedic procedures in a Hellenic Air Force Hospital. 在希腊空军医院进行选择性整形手术的病人中,预防措施束减少手术部位感染的有效性。
IF 0.6 Q4 SURGERY Pub Date : 2019-03-01
G Kritikou, K I Avgerinos, C Koutserimpas, F Sourri, D Hatzigeorgiou, C Kottaridi, I Bountouris

Background: Bundles of preventive measures may improve patient outcomes. The aim of this study is to investigate if a surgical site infections (SSIs) preventive bundle in orthopedic surgery patients can result in reduction of such infections, hospitalization length and cost.

Methods: The present is a retrospective cohort study. A total of 1299 patients was admitted to hospital for an elective orthopedic procedure during 2012-2015. The patients were subjected to either an integrated three-stage SSIs preventive protocol or standard preventive measures. The two groups were compared for incidence of SSIs, median hospitalization length and median cost.

Results: The incidence of SSIs was lower in the new-protocol group, when compared to the old protocol one (p=0.102). Median (md) hospitalization length was significantly lower in the new protocol group (md = 2) compared to "old-protocol" group (md= 5) [U = 280520, p<0.001]. Regarding arthroscopies, the median cost in the new protocol patients (md= 1500) was significantly lower compared to "old-protocol" patients (md= 1585) [(U= 112660), p < 0.001]. Knee arthroplasties' median costs did not differ (both mds= 4400, U = 2002, p > 0.05). For hip arthroplasties, the new protocol's patient median cost (md= 3000) was significantly lower than that of "old-protocol" (md = 4000) [U = 19680, p < 0.001].

Conclusions: The use of a bundle of measures for the prevention of SSIs in a hospital's orthopedic operations proved effective, since it resulted in substantial decrease of SSIs, statistically significant decreased hospitalization length, as well as cost.

背景:一系列的预防措施可以改善患者的预后。本研究的目的是探讨骨科手术患者手术部位感染(ssi)预防束是否可以减少此类感染、住院时间和费用。方法:回顾性队列研究。2012-2015年期间,共有1299名患者因择期骨科手术入院。患者接受综合三阶段ssi预防方案或标准预防措施。比较两组ssi发生率、中位住院时间和中位费用。结果:新方案组ssi发生率低于旧方案组(p=0.102)。新方案组的中位(md)住院时间(md= 2)明显低于“旧方案”组(md= 5) [U = 280520, p 0.05]。对于髋关节置换术,新方案的患者中位成本(md= 3000)显著低于“旧方案”(md= 4000) [U = 19680, p < 0.001]。结论:在某医院骨科手术中,采用一套预防ssi的措施是有效的,ssi发生率大幅下降,住院时间和费用均有统计学意义上的显著降低。
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引用次数: 0
Recurrent giant Brunner's gland adenoma. 复发性巨大布伦纳腺瘤。
IF 0.6 Q4 SURGERY Pub Date : 2019-03-01
J H Rodriguez-Quintero, O Santes, J Morales-Maza, U Clemente-Gutierrez, E Sanchez-Garcia Ramos, R Cortés-Gonzalez

Benign duodenal tumours are extremely rare, with an incidence of 0.008% among general population; those originating from Brunner's Gland represent 11% of this neoplasms. Most cases remain asymptomatic and are often diagnosed during routine endoscopic procedures, however their clinical presentation may be variable making resection treatment of choice in order to prevent complications. Recurrence has not been reported previously on literature. 59-year-old male presented to the emergency department nine months following endoscopic resection of a 2x1.5cm Brunner's gland adenoma complaining of bloating, weight loss and gastro intestinal bleeding, diagnostic approach revealed a 10x4cm mass occupying the duodenum. Tumour size did not allow for endoscopic resection and surgical removal was performed with excellent outcome and no further recurrence at 30 months.

良性十二指肠肿瘤极为罕见,在一般人群中的发病率仅为0.008%;源自布伦纳腺的占11%。大多数病例无症状,通常在常规内窥镜手术中诊断,然而他们的临床表现可能是可变的,为了防止并发症,选择切除治疗。既往文献未见复发报道。59岁男性,在内镜下切除2x1.5cm的布伦纳腺腺瘤9个月后到急诊室就诊,主诉腹胀、体重减轻和胃肠道出血,诊断方法显示一个10x4cm的肿块占据十二指肠。肿瘤大小不允许内镜切除,手术切除效果很好,30个月后没有进一步复发。
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引用次数: 0
Benign multicystic mesothelioma: a case report of recurrent disease in a young adult with familiarity for renal cell carcinoma. 良性多囊间皮瘤:一例年轻成人肾细胞癌复发病例报告。
IF 0.6 Q4 SURGERY Pub Date : 2019-03-01
N Falco, F Colli, R Tutino, T Fontana, L Licari, G Rotolo, G Scerrino, G Salamone, G Gulotta

Benign multi-cystic peritoneal mesothelioma (BMCM) is a very rare disease (about 150 cases observed). The aetiology is currently little-known, and the data collected, without having achieved conclusive re sults, identify two possible causes: neoplastic and reactive inflammatory. This case report refers to a recidivism of BCMC in a patient whose brother, few months before, underwent a left nephrectomy and right renal Radio Frequency Termo Ablation (RFTA) for bilateral papillary renal cell carcinoma. For the recurring trend, the onset in a male young patient without chronic inflammatory diseases evidence, the presence of a first degree relative with a rare carcinoma we supposed a neoplastic aetiology. The available literature suggests that both tumours (BCMC and renal cell carcinoma) are susceptible to oestrogens. This biomolecular mechanism could represent a valid antipathogenic hypothesis.

良性多囊性腹膜间皮瘤是一种非常罕见的疾病(约150例)。病因目前尚不清楚,收集的数据尚未取得结论性结果,确定了两种可能的原因:肿瘤和反应性炎症。本病例报告是一个BCMC再犯的病人,他的兄弟几个月前因双侧乳头状肾细胞癌接受了左肾切除术和右肾射频消融(RFTA)。对于复发的趋势,起病于男性年轻患者无慢性炎症疾病的证据,存在的一级亲属与罕见的癌症,我们认为是肿瘤的病因。现有文献表明,两种肿瘤(BCMC和肾细胞癌)都对雌激素敏感。这种生物分子机制可能是一种有效的抗病原假说。
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引用次数: 0
Choroidal metastasis from lung adenocarcinoma: a rare case report. 肺腺癌脉络膜转移一例。
IF 0.6 Q4 SURGERY Pub Date : 2019-03-01
C Porrello, R Gullo, C M Gagliardo, A Vaglica, M Palazzolo, F Giangregorio, D Iadicola, G Profita, F Lo Faso, G Tomasello, Fabrizio Carini, G Cocorullo

The choroid is the most common site for intraocular metastatic di sease. Orbital metastasis as metastatic site of lung adenocarcinoma is very rare and in literature a very exiguous number of cases is present. This is a case report of a woman with history of lung adenocarcinoma and, after surgery, detection of a choroidal mass described as lung metastasis, responding to Gefinitib therapy. However a biopsy was not performed. After two years there was a great dimension decrement of the lung metastasis but she is still suffering from recurrent pleural effusion, with pleural thickenings biopsied and diagnosed as recurrences of disease.

脉络膜是眼内转移性病变最常见的部位。眼眶转移作为肺腺癌的转移部位是非常罕见的,在文献中也有非常少的病例。这是一个有肺腺癌病史的女性病例报告,手术后,发现脉络膜肿块描述为肺转移,对吉非尼治疗有反应。然而,没有进行活检。两年后,肺转移灶的体积大大减小,但患者仍有反复胸腔积液,活检胸膜增厚,诊断为疾病复发。
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引用次数: 0
Can initial inflammatory markers predict length of stay in uncomplicated diverticulitis? 初始炎症标志物能否预测无并发症憩室炎的住院时间?
IF 0.6 Q4 SURGERY Pub Date : 2019-03-01
S Parys, A Eranki, S Khamhing

Aim: To investigate the ability of White Cell Count (WCC), Neutrophil count & C-Reactive Protein (CRP) levels at admission to predict length of stay (LOS) in patients with uncomplicated diverticulitis.

Method: This study was performed as a retrospective review of all patients admitted with CT proven uncomplicated diverticulitis over a one-year period. WCC, Neutrophils and CRP levels where recorded at admission. Uniform discharge criteria where used and length of stay measured. A correlation analysis was performed between the inflammatory markers and LOS.

Results: A total of 84 admissions with uncomplicated diverticulitis was included in this study. Average LOS 3.06 (range 1-7 days). On Romaadmission average CRP was 55 (1-276), WCC 11.5 (4.5-35.6) and Neutrophils 8.37 (2.3-18.9). Peak inflammatory values were also measured with mean peak CRP 93.5 (3-325), WCC 11.6 (5.1-35.6) and neutrophils 8.47 (2.3-18.9). Inflammatory markers were correlated to LOS. Multivariate analysis and Fit Plots showed no correlation between any of the inflammatory markers and LOS. Using a modified Hinchey classification 8 patients were Hinchey 0, 60 Hinchey Ia and 16 Hinchey Ib. Hinchey classification was associated with longer LOS (Hinchey 0 mean LOS 2.63 days, Hinchey Ia 2.71 days, Hinchey Ib 4.4 days).

Conclusion: There was a high degree of variation in the inflammatory markers at admission, as well as the peak level of these inflammatory markers during the patients stay. The extent to which these markers were raised did not correlate with the patients' length of stay. As such, the use of inflammatory markers has limited prognostic value in patients with uncomplicated diverticulitis.

目的:探讨入院时白细胞计数(WCC)、中性粒细胞计数和c反应蛋白(CRP)水平对非并发症憩室炎患者住院时间(LOS)的预测能力。方法:本研究对一年内所有CT证实无并发症的憩室炎患者进行回顾性分析。入院时记录WCC、中性粒细胞和CRP水平。使用统一的出院标准和测量停留时间。对炎症标志物与LOS进行相关性分析。结果:84例入院的无并发症憩室炎纳入本研究。平均LOS 3.06(范围1-7天)。入院时平均CRP为55 (1-276),WCC为11.5(4.5-35.6),中性粒细胞为8.37(2.3-18.9)。炎症峰值CRP平均峰值为93.5 (3-325),WCC平均峰值为11.6(5.1-35.6),中性粒细胞平均峰值为8.47(2.3-18.9)。炎症标志物与LOS相关。多变量分析和拟合图显示,任何炎症标志物与LOS之间均无相关性。采用改进的Hinchey分级,8例患者为Hinchey 0、60例Hinchey Ia和16例Hinchey Ib。Hinchey分级与较长的LOS相关(Hinchey 0平均LOS 2.63天,Hinchey Ia 2.71天,Hinchey Ib 4.4天)。结论:患者入院时炎症指标变化较大,住院期间炎症指标的峰值水平也存在较大差异。这些指标升高的程度与患者的住院时间无关。因此,使用炎症标志物对非并发症憩室炎患者的预后价值有限。
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引用次数: 0
Occasionally report of sacral chordoma; treatment and review of literature. 偶有骶脊索瘤的报道;文献的处理和回顾。
IF 0.6 Q4 SURGERY Pub Date : 2019-03-01
P Sallustio, M Minafra, R Laforgia, U Riccelli, P Lobascio, G Carbotta, G Balducci, N Palasciano

Introduction: Brain notochordal cell tumors (BTCN) are lesions arising from notochordal differentiation which affect the axial skeleton.

Presentation of case: We report a case of a patient treated in our General Surgery Unit of the University Hospital of Bari, Italy, with occasional finding of sacral chordoma at the histological examination.

Discussion: Because of their location, sacral chordomas can affect bowel and bladder with organ specific symptoms. Radiotherapy may be used as a palliative treatment or for recurrence in those patients who cannot be submitted to surgery.

Conclusions: Due to the high local recurrence rate radiation therapy should be considered mandatory after any type of chordoma resection. Multidisciplinary management of the disease is mandatory and improve patient outcomes. Patients should have maximal tumor debulking with adjuvant radiotherapy when possible.

脑脊索细胞瘤(BTCN)是由脊索分化引起的影响中轴骨骼的病变。病例介绍:我们报告一例在意大利巴里大学医院普通外科治疗的患者,在组织学检查中偶尔发现骶脊索瘤。讨论:由于其位置,骶脊索瘤可累及肠道和膀胱,并伴有器官特异性症状。放疗可作为姑息治疗或复发的病人谁不能提交手术。结论:任何类型脊索瘤切除后,由于局部复发率高,放射治疗应被认为是强制性的。疾病的多学科管理是强制性的,可以改善患者的预后。在可能的情况下,患者应最大限度地进行辅助放疗。
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引用次数: 0
An enhanced outpatient modality for the treatment of hemorrhoidal disease: preliminary results. 加强门诊治疗痔疮疾病的方式:初步结果。
IF 0.6 Q4 SURGERY Pub Date : 2019-03-01
K Perivoliotis, M Spyridakis, E Zintzaras, E Arnaoutoglou, M G Pramateftakis, K Tepetes

Surgical treatment of haemorrhoids is, primarily, performed on an outpatient basis, and as so, the reduction of the operative time and the hospitalization duration is necessary. In order to achieve these results, both the surgical procedure and the anaesthesia modality should be optimized. Therefore, in this randomized controlled trial, we proposed the hemorrhoidal arteries ligation under pudendal nerve block, as an enhanced outpatient modality, versus the standard of doppler guided hemorrhoidal arteries ligation under spinal anaesthesia. Preliminary results showed that the experimental group was characterized by a similar to the control arm, symptoms remission rate, a lower operation duration and an improved postoperative recovery.

痔疮的手术治疗主要在门诊进行,因此,减少手术时间和住院时间是必要的。为了达到这些效果,手术程序和麻醉方式都应该优化。因此,在这项随机对照试验中,我们提出了阴部神经阻滞下的痔动脉结扎作为一种增强的门诊方式,而不是脊髓麻醉下多普勒引导下的痔动脉结扎。初步结果显示,实验组与对照组相似,症状缓解率低,手术时间短,术后恢复较好。
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引用次数: 0
[Una vita a strati uniti. Il nutrimento e l'esercizio fisico per stare meglio oggi e domani]. 一种分层的生活。营养和运动使你今天和明天变得更好。
IF 0.6 Q4 SURGERY Pub Date : 2019-03-01
A Pulcini
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引用次数: 0
Is the social status a new prognostic factor in the Fournier's gangrene? 社会地位是富尼耶坏疽的一个新的预后因素吗?
IF 0.6 Q4 SURGERY Pub Date : 2019-03-01
B Capasso, M Pezzatini, M Cinquepalmi, M S Antonelli, G Caraceni, A Rampini, S Cardella, G Castagnola, S Maggi, A Brescia

Fournier's gangrene is a life-threatening acute necrotizing fasciitis of perianal, genitourinary and perineal areas. Local symptoms are scrotal swelling, erythema of scrotal skin and pain with generalized constitutional symptoms. The gangrene may extends to abdominal wall, intra-abdominal structures, and even in the retroperitoneal tissues. Urgent surgical debridement is crucial to warrant a good outcome since delayed intervention carries a poor prognosis. We report the case of a not diabetic patient with Fournier's disease presented with severe sepsis and successfully treated with urgent deep debridement and reconstructive surgery. We propose the social status of the patient as a prognostic factor with high impact for survival rate.

富尼耶坏疽是一种危及生命的急性坏死性筋膜炎肛周,泌尿生殖系统和会阴区。局部症状为阴囊肿胀、阴囊皮肤红斑和全身疼痛。坏疽可扩展到腹壁、腹内结构,甚至腹膜后组织。紧急手术清创是保证良好结果的关键,因为延迟干预会带来不良预后。我们报告一例非糖尿病的富尼耶氏病患者表现为严重的败血症,并成功地接受了紧急深度清创和重建手术。我们认为患者的社会地位是影响生存率的一个预后因素。
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引用次数: 0
期刊
Giornale di Chirurgia
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