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A Randomized Crossover, Pilot Study Examining the Effect of Acupuncture in the Management of Competitive Anxiety in Athletes. 一项随机交叉试验研究针刺在运动员竞技焦虑管理中的作用。
IF 1 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2021-08-31 DOI: 10.51507/j.jams.2021.14.4.149
Mohammad Khojastefar, Maryam Selk-Ghaffari, Amir-Hossein Memari, Farzin Halabchi, Tohid Seif-Barghi

Background: Excessive competitive anxiety induces adverse effects on athletic performance and planning efficient management methods is crucial. Objectives: We aimed to assess the effects of acupuncture on competitive anxiety.

Methods: In this cross-over study, 20 male soccer players under 21 years (U-21) were randomized equally into acupuncture or control groups. The acupuncture group received acupuncture on fifteen anxiety-related points and the control group received acupuncture on fifteen points unrelated to anxiety for thirty minutes. We measured the participants' resting heart rate and galvanic skin conduction and asked them to answer the Competitive State Anxiety Inventory-2 (CSAI-2) questionnaire at baseline and the end of the intervention.

Results: We detected a significant treatment effect in the cognitive anxiety level (-1.05 ± 0.91; p = 0.02) but not in the somatic anxiety level (-0.46 ± 1.68; p = 0.43), Sport Self-Confidence (-1.06 ± 2.21; p = 0.11), heart rate (0.20 ± 2.2; p = 0.93), and skin conductance (-0.50 ± 0.77; p = 0.19).

Conclusion: Based on these results, acupuncture might decrease cognitive anxiety but might not affect somatic anxiety.

背景:过度的竞争焦虑会对运动成绩产生不利影响,规划有效的管理方法至关重要。目的:我们旨在评估针灸对竞争性焦虑的影响。方法:在交叉研究中,20名21岁以下(U-21)的男子足球运动员随机分为针灸组和对照组。针灸组接受15个与焦虑有关的穴位的针灸,对照组接受15个与焦虑无关的穴位的针灸,持续30分钟。我们测量了参与者的静息心率和皮肤电传导,并要求他们在基线和干预结束时回答竞争状态焦虑量表-2 (CSAI-2)问卷。结果:治疗对认知焦虑水平有显著影响(-1.05±0.91;P = 0.02),躯体焦虑水平差异无统计学意义(-0.46±1.68;p = 0.43),运动自信(-1.06±2.21;P = 0.11),心率(0.20±2.2;P = 0.93),皮肤电导率(-0.50±0.77;P = 0.19)。结论:针刺可降低认知焦虑,但对躯体焦虑无影响。
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引用次数: 2
Heart Rate Variability and Psychometric Analysis in Patients with Hyperactive Heart Fire Syndrome. 心火多动综合征患者的心率变异性和心理测量学分析。
IF 1 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2021-08-31 DOI: 10.51507/j.jams.2021.14.4.137
Oliverio Medina Martínez, Ruben Fossion, Yolanda García Piceno, Rosa E Lopez-Gomez, Emma López-Espinosa, Ismael Jiménez-Estrada, Salvador Quiroz-González

Background: Hyperactive heart fire syndrome is characterized by anxiety, insomnia, dream-disturbed sleep, tongue ulcers, heat in the hands, and palpitations. However, syndrome differentiation is often subjective due to a lack of objective, quantifiable variables. Objectives: To identify changes in heart rate variability (HRV) and psychometric analysis in patients with hyperactive heart fire syndrome.

Methods: Healthy controls (n = 33) were compared to patients with hyperactive heart fire syndrome (n = 48) from the Integrative University Clinic of the State University of Ecatepec Valley (CIU-UNEVE). Physiological outcome measures included heart rate (HR), the standard deviation of the normal-to-normal heartbeat intervals (SDNN), low (LF) and high frequency (HF) power, and the LF/HF ratio. Psychometric outcome measures included the Athens Insomnia Scale (AIS) and the Hamilton Anxiety Rating Scale (HARS).

Results: Compared to controls, hyperactive heart fire patients had higher HR (9.6 ± 2.62%), LF (22 ± 4.21%) and LF/HF ratio (23 ± 3.14%), and lower SDNN (21 ± 2.33%) and HF (18 ± 4.61%). Patients showed increased anxiety, both with somatic (33 ± 11.2%) and psychic symptoms (39 ± 10.5%) with more difficulty falling asleep (47 ± 9.9%) and diurnal impact of sleep (31 ± 9.6%).

Conclusion: Hyperactive heart fire patients may have a sympathovagal imbalance due to a reduced parasympathetic tone and/or adominant sympathetic tone, which may be at the origin of the observed symptoms of insomnia and anxiety.

背景:心火亢进综合征的特点是焦虑、失眠、梦扰睡眠、舌溃疡、手热和心悸。然而,由于缺乏客观的、可量化的变量,辨证往往是主观的。目的:探讨心火多动综合征患者心率变异性(HRV)的变化及心理测量学分析。方法:将健康对照组(n = 33)与来自埃卡特佩克谷州立大学综合大学诊所(CIU-UNEVE)的心火综合征患者(n = 48)进行比较。生理结果测量包括心率(HR)、正常至正常心跳间隔(SDNN)的标准差、低频(LF)和高频(HF)功率以及LF/HF比值。心理测量结果测量包括雅典失眠量表(AIS)和汉密尔顿焦虑评定量表(HARS)。结果:与对照组相比,高活动性心火患者HR(9.6±2.62%)、LF(22±4.21%)、LF/HF(23±3.14%)较高,SDNN(21±2.33%)、HF(18±4.61%)较低。患者表现出焦虑加重,躯体症状(33±11.2%)和精神症状(39±10.5%),入睡困难(47±9.9%)和睡眠日影响(31±9.6%)。结论:心火过度活跃患者可能由于副交感神经张力和/或主交感神经张力降低而出现交感神经失衡,这可能是观察到的失眠和焦虑症状的根源。
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引用次数: 2
The 2nd International Symposium of Primo-vascular System. 第二届国际原始血管系统学术研讨会。
IF 1 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2021-06-30 DOI: 10.51507/j.jams.2021.14.3.A001
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引用次数: 0
Identification of Cleaved Haptoglobin in the Serum of Bee Venom-Hypersensitive Patients. 蜜蜂毒液过敏患者血清中裂裂型触珠蛋白的鉴定。
IF 1 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2021-06-30 DOI: 10.51507/j.jams.2021.14.3.102
Jae-Min Ryu, Han-Heom Na, Jin-Sung Park, Byung-Soo Ahn, Keun-Cheol Kim

Background: Bee venom has been used as a therapeutic compound for various human diseases in oriental medicine; however, it can induce anaphylaxis in hypersensitive patients during treatment. Anaphylaxis is an acute allergic reaction that occurs after allergen exposure. IgE is released from immune-related cells such as mast cells and basophils during anaphylaxis. Various inflammatory mediators are also released into the bloodstream during the acute response.

Objectives: We aimed to identify specific proteins from bee venom-hypersensitive patients.

Methods: We analyzed the blood serum of control and bee venom-hypersensitive patients using two-dimensional (2D) electrophoresis.

Results: An interesting protein spot with a molecular size of 10 kDa was identified at an isoelectric point (p.I.) of 5.5. Spots detected both before and after sweet bee venom therapy were not proteins induced by sweet bee venom. The 10 kDa protein was identified as the cleaved form of haptoglobin through liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis. Statistical analysis indicated that the presence of the spot was highly significant in the bee venom-hypersensitive group.

Conclusion: The findings suggest that cleaved haptoglobin may be a significant diagnostic protein for anaphylaxis. In addition, a high incidence of bee venom hypersensitivity may be associated with the haptoglobin genotype.

背景:在东方医学中,蜂毒已被用作治疗各种人类疾病的药物;然而,在治疗过程中,它可以引起过敏反应的过敏患者。过敏反应是在接触过敏原后发生的急性过敏反应。在过敏反应期间,IgE从免疫相关细胞如肥大细胞和嗜碱性细胞释放出来。在急性反应期间,各种炎症介质也被释放到血液中。目的:我们旨在鉴定蜜蜂毒液过敏患者的特异性蛋白质。方法:采用二维电泳法对对照组和蜂毒过敏患者的血清进行分析。结果:在等电点(pi)为5.5处发现了一个分子量为10 kDa的有趣蛋白点。甜蜂毒治疗前后检测到的斑点均不是甜蜂毒诱导的蛋白。通过液相色谱-串联质谱(LC-MS/MS)分析,鉴定了10 kDa蛋白为裂裂形式的触珠蛋白。统计分析表明,该斑点的存在是高度显著的蜜蜂毒液过敏组。结论:裂化接触珠蛋白可能是一种重要的过敏反应诊断蛋白。此外,蜂毒过敏的高发可能与触珠蛋白基因型有关。
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引用次数: 1
Treatment of Masticatory Muscle Pain with Acupuncture: Is It Necessary to Associate with Occlusal Splints? 针刺治疗咀嚼肌痛:是否需要配合咬合夹板?
IF 1 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2021-06-30 DOI: 10.51507/j.jams.2021.14.3.89
Crischina Branco Marques Sant'Anna, Fernanda Pereira de Caxias, Paulo Renato Junqueira Zuim, Marcella Santos Januzzi, Emily Viviane Freitas da Silva, Karina Helga Leal Turcio

Background: Temporomandibular disorders (TMDs) are treated by different modalities including splints, physiotherapy, and acupuncture. Although all of these offer evidencebased benefits to the patients, avoiding overtreatment is of paramount importance.

Objectives: To assess the effectiveness of muscle pain treatment with acupuncture combined with or without occlusal splints.

Methods: Recruited patients were allocated to G1 (acupuncture) and G2 (acupuncture and occlusal splint) groups and treated in four consecutive weekly sessions (P1, P2, P3, and P4). The reported pain (RP) and the pressure pain threshold (PPT) of the masseter and temporalis muscles were assessed before and after each session.

Results: RP decreased after each session in G1, except at P4. In G2, the RP decreased only after the first session, and the PPT did not vary.

Conclusion: The assessed treatments did not influence the PPT levels of the masseter and anterior temporalis muscles in patients with temporomandibular disorders. Our findings suggest that occlusal splints may not be mandatory along with the acupuncture treatment.

背景:颞下颌疾病(TMDs)的治疗方式不同,包括夹板、物理治疗和针灸。尽管所有这些都为患者提供了基于证据的益处,但避免过度治疗是至关重要的。目的:评价针刺配合或不配合咬合夹板治疗肌肉疼痛的疗效。方法:将招募的患者分为G1组(针刺组)和G2组(针刺+咬合夹板组),每周连续治疗4次(P1、P2、P3、P4)。在每次训练前后评估咬肌和颞肌的报告疼痛(RP)和压力痛阈(PPT)。结果:除P4外,G1期每次疗程后RP均下降。在G2中,RP仅在第一次治疗后下降,PPT没有变化。结论:所评估的治疗方法对颞下颌障碍患者的咬肌和颞前肌PPT水平无影响。我们的研究结果表明,咬合夹板可能不强制与针灸治疗。
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引用次数: 1
An Immunological Hypothesis of Fu's Subcutaneous Needling Acupuncture. 傅皮下针刺的免疫学假说。
IF 1 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2021-06-30 DOI: 10.51507/j.jams.2021.14.3.110
Wenbo Xu, Jidong Wu, Ping Xu

Fu's subcutaneous needling (FSN) is a novel acupuncture approach. Although it has been popularized and widely used by acupuncture practitioners, theoretical research on its mechanism of action remains lacking. This study establishes an immunological hypothesis for the efficacy of FSN basis existing knowledge in biomedical science, histology and physiology, and traditional acupuncture mechanisms. The theoretical inference indicates that FSN treatment may affect the body's immune system through subcutaneous connective tissue, similar to triggering a cobweb-like system. This article also proposes possible clinical implications of this theory, which require further studies to validate.

傅氏皮下针刺(FSN)是一种新颖的针刺方法。虽然它已被针灸从业者广泛推广和使用,但其作用机制的理论研究仍然缺乏。本研究基于生物医学、组织生理学和传统针刺机制的现有知识,建立了FSN疗效的免疫学假说。理论推断FSN治疗可能通过皮下结缔组织影响机体免疫系统,类似于触发蛛网状系统。本文还提出了该理论可能的临床意义,这需要进一步的研究来验证。
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引用次数: 1
The Effect of Acupressure on Clinical Stress Management in Nursing Students: A Randomised Controlled Study. 穴位按压对护生临床应激管理的影响:一项随机对照研究。
IF 1 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2021-06-30 DOI: 10.51507/j.jams.2021.14.3.95
Dilek Yildirim, Özlem Akman

Background: Nursing students experience clinical stress frequently and severely. The application of acupressure is reported to be effective in stress management.

Objectives: This study was conducted to determine the effects of acupressure on reducing the stress of nursing students in clinical practice.

Methods: This study was carried out using a single-blind randomized controlled experimental design. The experimental and control groups were randomly determined by using a previously prepared randomization checklist. A Participant Information Form, VAS, and the State Anxiety Inventory were applied to all students before practice. Acupressure was performed on the HT7 point and Yintang point (EX-HN3), respectively, every five minutes for a total of 30 minutes in the experimental group.

Results: The level of stress experienced by the students in the experimental group before the intervention according to VAS was 6.95 ± 1.57, and it was determined as 2.82 ± 1.94 after the third application (p < 0.05). The mean clinical stress score before the application was 46.54 ± 3.81, and after the 3rd week of application, it was 25.15 ± 5.26 (p < 0.05). It was observed that the students' stress levels decreased in all measurements made after the acupressure intervention.

Conclusion: This study determined that acupressure effectively reduces the stress levels of nursing students, and it may be applied in clinical stress management.

背景:护生临床应激频繁且严重。据报道,穴位按压在压力管理中是有效的。目的:探讨穴位按压对护理学生临床应激的影响。方法:采用单盲随机对照试验设计。使用事先准备的随机清单随机确定实验组和对照组。在练习前对所有学生使用参与者信息表、VAS和状态焦虑量表。实验组分别穴位按压HT7穴和音堂穴(EX-HN3),每5分钟一次,共30分钟。结果:实验组学生干预前的应激水平VAS为6.95±1.57,第三次应用后的应激水平VAS为2.82±1.94 (p < 0.05)。用药前临床应激评分平均为46.54±3.81,用药第3周后临床应激评分平均为25.15±5.26 (p < 0.05)。我们观察到,在穴位按摩干预后,学生的压力水平在所有测量中都有所下降。结论:穴位按压能有效降低护生的应激水平,可应用于临床应激管理。
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引用次数: 2
Effect of Acupressure on Primary Dysmenorrhea: Review of Experimental Studies. 穴位按压治疗原发性痛经的实验研究综述。
IF 1 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2021-04-30 DOI: 10.51507/j.jams.2021.14.2.33
Aslı Karakuş Selçuk, Emre Yanikkerem

Primary dysmenorrhea is defined as cramping pain in the lower abdomen with no pelvic diseases, and it has a high prevalence in many countries. Acupressure is a widely used complementary treatment method for primary dysmenorrhea. This review examined experimental studies to determine the effects of acupressure on primary dysmenorrhea using the databases PubMed, Google Scholar, and CINAHL with the keywords "Acupressure" and "Dysmenorrhea". There were 2227 records in the databases, and 330 articles were published between 1989 and March 2020. Experimental studies in the English language were reviewed according to the PRISMA guidelines. This review included 28 published studies that were assessed using the Jadad score for quality. The studies were categorized as studies of acupressure at the LR3 point (n = 4), at the SP6 point (n = 9), at auricular points (n = 5), at multiple points (n = 8), and with devices (n = 2). Moreover, studies of self-acupressure (n = 9) were identified. The studies demonstrated that acupressure could reduce menstrual symptoms, the severity and duration of menstrual pain, distress, and anxiety. Furthermore, it helped improve the quality of life and well-being of patients and provide psychological support and self-care. Acupressure is an inexpensive, easy-to-apply, and non-pharmacological treatment and is useful for reducing primary dysmenorrhea, and women can apply this method anywhere by themselves. However, high-quality randomized controlled trials with larger samples are necessary to establish the evidence for acupressure as an effective intervention.

原发性痛经被定义为没有盆腔疾病的下腹绞痛性疼痛,在许多国家发病率很高。穴位按压是一种广泛应用于原发性痛经的辅助治疗方法。本文通过检索PubMed、Google Scholar和CINAHL数据库,检索关键词为“穴位按压”和“痛经”的实验研究,以确定穴位按压对原发性痛经的影响。数据库中有2227条记录,1989年至2020年3月期间发表了330篇文章。根据PRISMA指南对英语实验研究进行了审查。本综述纳入了28项已发表的研究,使用Jadad评分进行质量评估。这些研究被归类为LR3点(n = 4)、SP6点(n = 9)、耳穴(n = 5)、多点(n = 8)和带器械(n = 2)的穴位按压研究。此外,还确定了自我穴位按压研究(n = 9)。研究表明,穴位按压可以减轻经期症状,减轻经期疼痛、苦恼和焦虑的严重程度和持续时间。此外,它有助于改善患者的生活质量和福祉,并提供心理支持和自我保健。穴位按压是一种廉价、易于使用、非药物的治疗方法,对减轻原发性痛经很有用,女性可以自己在任何地方使用这种方法。然而,大样本的高质量随机对照试验是必要的,以建立穴位按压作为有效干预的证据。
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引用次数: 3
Visible Meridian Phenomena after Acupuncture: A Series of Case Reports. 针刺后可见经络现象:一系列病例报告。
IF 1 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2021-04-30 DOI: 10.51507/j.jams.2021.14.2.50
Nikolay Dimitrov, Nikola Tomov, Dimitrinka Atanasova, Stiliyan Iliev, Tatyana Tomova, Dimitar Sivrev, Zoya Goranova

Background: In accordance with the meridian theory of Traditional Chinese Medicine (TCM), meridian phenomena are observed along the course of a meridian following acupuncture. Their visible manifestations include alterations in the color (reddening or whitening) of the skin as well as papule and vesicle formation.

Objectives: The aim of the present work is to report a series of visible meridian phenomena manifested in human subjects and to correlate them to TCM concepts. A total of 1,200 patients, on whom classical acupuncture (with standard single-use needles without electrostimulation or moxibustion) was applied, were carefully observed and documented.

Methods: Visible meridian phenomena were photographed using standard photographical equipment and compared to classical acupuncture channels used by TCM.

Results: Ten patients (5 male, 5 female) exhibited visible meridian phenomena. Lines, concurring with the meridians, were observed: white lines in seven cases and red lines in three cases. The duration of the two kinds of phenomena was different. White lines remained visible for a shorter period (10-15 min), whereas red lines were seen for up to one hour after needle removal.

Conclusion: These observations indicate that visible meridian phenomena following acupuncture are objective, albeit rare, findings that coincide with the acupuncture channels described in the classical works of TCM. The presence of such phenomena provides a new insight into the concept of meridians and explains the development of the idea in its historical context.

背景:根据中医的经络理论,经络现象是在针灸后沿着经络的过程中观察到的。其可见的表现包括皮肤颜色的改变(变红或变白)以及丘疹和囊泡的形成。目的:本工作的目的是报道一系列可见的经络现象,并将其与中医概念联系起来。研究人员仔细观察并记录了1200名接受经典针灸(使用标准的一次性针,不使用电刺激或艾灸)治疗的患者。方法:采用标准摄影器材拍摄可见经络现象,并与中医经典针灸经络进行对比。结果:10例患者(男5例,女5例)均可见经络现象。与经络重合的线:白线7例,红线3例。这两种现象持续的时间不同。白线的可见时间较短(10-15分钟),而红线在取针后一小时内仍可见。结论:针刺后可见经络现象是客观的,尽管罕见,但与中医经典著作中描述的针灸经络相吻合。这种现象的存在提供了对经络概念的新见解,并解释了这一概念在其历史背景下的发展。
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引用次数: 2
Comparison between the Effectiveness of Manual Acupuncture and Laser Acupuncture at EX-B3 Weiwanxiashu in a Rat Model of Type 2 Diabetes. 在2型糖尿病大鼠模型中EX-B3胃脘下舒的手动针灸和激光针灸效果的比较。
IF 1 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2021-04-30 DOI: 10.51507/j.jams.2021.14.2.75
Ahmad Aulia Jusuf, Yoshua Viventius, Wahyuningsih Djaali

Background: Diabetes mellitus (DM) is a chronic metabolic disease characterized by increased blood sugar levels. The current management of DM to date has a target of controlling blood glucose, but the therapy cannot be separated from long-term drug side effects. Acupuncture can be an option as an adjunct therapy for DM.

Objectives: The purpose of this study was to compare the effectiveness between manual acupuncture and laser acupuncture.

Methods: This study was a randomized control experimental study with a pretest and posttest design using 24 male Sprague-Dawley rats divided into 4 groups: a normal group, a diabetes group, an acupuncture group, and a laser group. Manual acupuncture and laser acupuncture were performed 6 times in two weeks. Fasting blood glucose (FBG) levels, the cell density of Langerhans islets, and side effects were assessed and compared among the 4 groups.

Results: The highest mean cell density of Langerhans islets was found in the laser and acupuncture group, and the lowest was found in the diabetes group. In the post hoc analysis, the normal, acupuncture, and the laser groups had a significantly higher mean cell density than the diabetes group. The lowest mean FBG level was in the laser group, followed by the acupuncture group, and the highest was in the diabetes group, but this difference was not significant. There were no serious side effects from the use of manual acupuncture or laser acupuncture.

Conclusion: Both manual acupuncture and laser acupuncture can improve the histological findings of Langerhans islets in type 2 diabetic rats, and both are safe to use.

背景:糖尿病是一种以血糖水平升高为特征的慢性代谢性疾病。到目前为止,糖尿病的治疗目标是控制血糖,但这种治疗离不开长期的药物副作用。针灸可以作为DM的辅助治疗选择。目的:本研究的目的是比较手法针灸和激光针灸的有效性。方法:本研究是一项随机对照实验研究,采用前测和后测设计,使用24只雄性Sprague-Dawley大鼠,分为4组:正常组、糖尿病组、针灸组和激光组。在两周内进行了6次手法针灸和激光针灸。评估并比较了4组患者的空腹血糖(FBG)水平、胰岛细胞密度和副作用。结果:激光组和针灸组胰岛平均细胞密度最高,糖尿病组最低。在事后分析中,正常组、针灸组和激光组的平均细胞密度显著高于糖尿病组。平均FBG水平最低的是激光组,其次是针灸组,最高的是糖尿病组,但这一差异并不显著。使用手动针灸或激光针灸没有严重的副作用。结论:手针和激光针均能改善2型糖尿病大鼠胰岛的组织学表现,使用安全。
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引用次数: 3
期刊
Journal of Acupuncture and Meridian Studies
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