Pub Date : 2023-10-31DOI: 10.47825/jkgp.2023.27.2.71
Woo Youn Jung, Seul Gi Koo, Young Ju Kim, Seong-A Lee, Hyu Seok Jeong, Do Hyun Kim, Kyung Min Kim, Jung Jae Lee, Seok Bum Lee
Objective: This study explored the efficacy of group reminiscence therapy, incorporating traditional plays, for individuals with mild cognitive impairment (MCI) and dementia patients.
Methods: We provided 10 sessions of group reminiscence therapy to 25 MCI and dementia patients. We conducted assessments, both before and after the program, encompassing a range of tests, namely the Mini-Mental Status Examination (MMSE), Dysexecutive Questionnaire, Zarit Burden Interview (ZBI-K), Dementia Care Assessment Packet-Instrumental Activities of Daily Living, Geriatric Depression Scale (GDS-K), and Neuropsychiatric Inventory (NPI-K).
Results: Following the program, there was a significant improvement in MMSE scores for MCI patients (19.17 to 22.33, p=0.027). There was a significant improvement in NPI-K scores for dementia patients (8.05 to 3.74, p=0.006). There was a significant improvement in GDS-K scores for MCI patients (17.00 to 14.00, p=0.043). There was a significant improvement in ZBIK scores for dementia (28.53 to 17.68, p=0.001) and MCI patients (29.17 to 16.33, p=0.046).
Conclusion: Our study suggested that group reminiscence therapy based on traditional play might be effective in global cognition of MCI patients, neuropsychological symptoms of dementia patients, depression of MCI patients, and caregiver burden of all subjects.
{"title":"Effects of Group Reminiscence Therapy Based on Korean Traditional Play for Mild Cognitive Impairment and Dementia Patients","authors":"Woo Youn Jung, Seul Gi Koo, Young Ju Kim, Seong-A Lee, Hyu Seok Jeong, Do Hyun Kim, Kyung Min Kim, Jung Jae Lee, Seok Bum Lee","doi":"10.47825/jkgp.2023.27.2.71","DOIUrl":"https://doi.org/10.47825/jkgp.2023.27.2.71","url":null,"abstract":"Objective: This study explored the efficacy of group reminiscence therapy, incorporating traditional plays, for individuals with mild cognitive impairment (MCI) and dementia patients.
 Methods: We provided 10 sessions of group reminiscence therapy to 25 MCI and dementia patients. We conducted assessments, both before and after the program, encompassing a range of tests, namely the Mini-Mental Status Examination (MMSE), Dysexecutive Questionnaire, Zarit Burden Interview (ZBI-K), Dementia Care Assessment Packet-Instrumental Activities of Daily Living, Geriatric Depression Scale (GDS-K), and Neuropsychiatric Inventory (NPI-K).
 Results: Following the program, there was a significant improvement in MMSE scores for MCI patients (19.17 to 22.33, p=0.027). There was a significant improvement in NPI-K scores for dementia patients (8.05 to 3.74, p=0.006). There was a significant improvement in GDS-K scores for MCI patients (17.00 to 14.00, p=0.043). There was a significant improvement in ZBIK scores for dementia (28.53 to 17.68, p=0.001) and MCI patients (29.17 to 16.33, p=0.046).
 Conclusion: Our study suggested that group reminiscence therapy based on traditional play might be effective in global cognition of MCI patients, neuropsychological symptoms of dementia patients, depression of MCI patients, and caregiver burden of all subjects.","PeriodicalId":471642,"journal":{"name":"Noin jeongsin yihag","volume":"79 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135976575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-31DOI: 10.47825/jkgp.2023.27.2.59
Min Hong Lee, Min Jae Kang, Woo Jung Kim
Objective: This study aimed to assess the usefulness of a memory complaint questionnaire for predicting amyloid PET positivity in community-dwelling older adults.
Methods: We recruited community-dwelling older adults without history of dementia who wished to participate in the study based on voluntary consent. We performed the Seoul Neuropsychological Screening Battery-Core (SNSB-C), Memory Age-associated Complaint Questionnaire (MACQ), Apolipoprotein E (ApoE) genotyping, and amyloid PET. According to the result of the SNSB-C, participants with objective cognitive impairment were excluded, and finally 124 participants were included in this study. We used receiver operating characteristic (ROC) curve and calculated area under the ROC curve (AUC) to evaluate usefulness of the MACQ compared to the result of ApoE genotyping for predicting amyloid PET positivity in cognitively unimpaired community-dwelling older adults.
Results: The mean age of the study participants was 73.3 years, and 69.4% were female. ROC curve with MACQ score and with ApoE4 carrier was created and AUC of each model was calculated. AUC value was 0.660 for MACQ score, and 0.695 for ApoE4 carrier. There was no statistically significant difference in AUC value (p=0.494).
Conclusion: In community-dwelling older adults without objective cognitive decline, the memory complaint questionnaire― MACQ showed no significant difference with ApoE4 carrier for predicting amyloid PET positivity.
{"title":"Usefulness of a Memory Complaint Questionnaire for Predicting Amyloid PET Positivity in Community-Dwelling Older Adults","authors":"Min Hong Lee, Min Jae Kang, Woo Jung Kim","doi":"10.47825/jkgp.2023.27.2.59","DOIUrl":"https://doi.org/10.47825/jkgp.2023.27.2.59","url":null,"abstract":"Objective: This study aimed to assess the usefulness of a memory complaint questionnaire for predicting amyloid PET positivity in community-dwelling older adults.
 Methods: We recruited community-dwelling older adults without history of dementia who wished to participate in the study based on voluntary consent. We performed the Seoul Neuropsychological Screening Battery-Core (SNSB-C), Memory Age-associated Complaint Questionnaire (MACQ), Apolipoprotein E (ApoE) genotyping, and amyloid PET. According to the result of the SNSB-C, participants with objective cognitive impairment were excluded, and finally 124 participants were included in this study. We used receiver operating characteristic (ROC) curve and calculated area under the ROC curve (AUC) to evaluate usefulness of the MACQ compared to the result of ApoE genotyping for predicting amyloid PET positivity in cognitively unimpaired community-dwelling older adults.
 Results: The mean age of the study participants was 73.3 years, and 69.4% were female. ROC curve with MACQ score and with ApoE4 carrier was created and AUC of each model was calculated. AUC value was 0.660 for MACQ score, and 0.695 for ApoE4 carrier. There was no statistically significant difference in AUC value (p=0.494).
 Conclusion: In community-dwelling older adults without objective cognitive decline, the memory complaint questionnaire― MACQ showed no significant difference with ApoE4 carrier for predicting amyloid PET positivity.","PeriodicalId":471642,"journal":{"name":"Noin jeongsin yihag","volume":"154 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135976878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-31DOI: 10.47825/jkgp.2023.27.2.65
Surin Seo, Won Seok William Hyung, Seung-Hoon Lee, Junhyung Kim, Kwang-Yeon Choi, HyunChul Youn, Hyun-Ghang Jeong
Objective: Cognitive dysfunction is frequently reported after surgery and anesthesia in elderly patients. This study aims to investigate the incidence of dementia for eight years after anesthesia.
Methods: We extracted the data between 2007 and 2020 from the Health Insurance Review and Assessment Service Database. We analyzed risk of developing dementia after anesthesia using Cox proportional hazard models.
Results: Data were collected from 62,541 patient. Among them, subjects with and without anesthesia were 15,857 and 46,684, respectively. Subjects with anesthesia had more hypertension, diabetes mellitus and hyperlipemia than those without anesthesia. The risk of dementia incidence was found to increase 1.7 times in subjects with anesthesia (hazard ratio=1.751, 95% confidence interval=1.596-1.921). Even after the correction for gender, age, and comorbidity, the statistical significance of this risk remained (hazard ratio=1.662, 95% confidence interval=1.512-1.827).
Conclusion: Our findings suggest that anesthesia possibly contribute on cognitive impairment. Clinician might need closed observation on cognitive function in patients after surgery and anesthesia.
{"title":"Influence of Anesthesia on Incidence of Dementias: 8-Year Follow-Up Study","authors":"Surin Seo, Won Seok William Hyung, Seung-Hoon Lee, Junhyung Kim, Kwang-Yeon Choi, HyunChul Youn, Hyun-Ghang Jeong","doi":"10.47825/jkgp.2023.27.2.65","DOIUrl":"https://doi.org/10.47825/jkgp.2023.27.2.65","url":null,"abstract":"Objective: Cognitive dysfunction is frequently reported after surgery and anesthesia in elderly patients. This study aims to investigate the incidence of dementia for eight years after anesthesia.
 Methods: We extracted the data between 2007 and 2020 from the Health Insurance Review and Assessment Service Database. We analyzed risk of developing dementia after anesthesia using Cox proportional hazard models.
 Results: Data were collected from 62,541 patient. Among them, subjects with and without anesthesia were 15,857 and 46,684, respectively. Subjects with anesthesia had more hypertension, diabetes mellitus and hyperlipemia than those without anesthesia. The risk of dementia incidence was found to increase 1.7 times in subjects with anesthesia (hazard ratio=1.751, 95% confidence interval=1.596-1.921). Even after the correction for gender, age, and comorbidity, the statistical significance of this risk remained (hazard ratio=1.662, 95% confidence interval=1.512-1.827).
 Conclusion: Our findings suggest that anesthesia possibly contribute on cognitive impairment. Clinician might need closed observation on cognitive function in patients after surgery and anesthesia.","PeriodicalId":471642,"journal":{"name":"Noin jeongsin yihag","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135976270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-31DOI: 10.47825/jkgp.2023.27.2.52
Hyun Kim, Kang Joon Lee
Objective: As the elderly population increases, the proportion of neurocognitive disorder is increasing. Accordingly, research on cognitive intervention therapy to prevent neurocognitive disorder is also becoming active. In particular, this study attempted to evaluate changes in cognitive function before and after training and verify their effectiveness by implementing a computerized cognitive training program for patients with mild cognitive impairment.
Methods: A computerized cognitive training program was conducted for 15 patients with mild cognitive impairment. It was conducted twice a week, 30 minutes, and 16 times for 8 weeks, and neurocognitive function was evaluated before and after training. The neurocognitive function tests are as follows; Seoul Neuropsychological Screening Battery, Korean version of Montreal Cognitive Assessment (K-MoCA), Clinical Dementia Rating (CDR), Korean Instrumental Activity of Daily Living (K-IADL), Korean Neuropsychiatric Inventory (K-NPI), and Memory Age-associated Complaint Questionnaire (MAC-Q).
Results: There was a statistically significant improvement in memory domain after the implementation of the computerized cognitive training program, but no significant changes in attention, language ability, visuospatial function, and frontal lobe executive function. Among the memory areas, the Seoul Verbal Learning Test: Delayed Recall, Rey Complex Figure Test: Delayed Recall, and Rey Complex Figure Test: Recognition are showed significant improvement. In addition, there was a significant improvement in CDR (sum of box) and K-MoCA scores. There was no statistically significant difference in K-IADL and K-NPI.
Conclusion: Computerized cognitive training programs have been effective in improving memory in patients with mild cognitive impairment. In order to verify the effectiveness of dementia prevention, a long-term study of a larger number is needed. The results of this preliminary study will help develop and apply cognitive training contents in the future.
目的:随着老年人口的增加，神经认知障碍的比例越来越高。因此，预防神经认知障碍的认知干预疗法研究也日趋活跃。特别是，本研究试图评估训练前后认知功能的变化，并通过对轻度认知障碍患者实施计算机认知训练计划来验证其有效性。
方法:对15例轻度认知障碍患者进行计算机化认知训练。每周2次，每次30分钟，共16次，共8周，并在训练前后评估神经认知功能。神经认知功能测试如下;首尔神经心理筛查组，韩国版蒙特利尔认知评估(K-MoCA)，临床痴呆评分(CDR)，韩国日常生活工具活动(K-IADL)，韩国神经精神量表(K-NPI)，记忆年龄相关投诉问卷(MAC-Q)。
结果:计算机化认知训练方案实施后，记忆领域有统计学意义上的改善，但在注意力、语言能力、视觉空间功能和额叶执行功能方面无显著变化。在记忆领域中，首尔语言学习测试(延迟回忆)、雷伊复杂图形测试(延迟回忆)、雷伊复杂图形测试(识别)表现出明显的改善。此外，CDR (sum of box)和K-MoCA评分也有显著改善。K-IADL、K-NPI差异无统计学意义。
结论:计算机化认知训练方案对改善轻度认知障碍患者的记忆有较好的效果。为了验证痴呆症预防的有效性，需要进行更大规模的长期研究。本研究的初步结果将有助于未来认知训练内容的开发和应用。
{"title":"The Effectiveness of Computerized Cognitive Training Program for Older Adults With Mild Cognitive Impairment: Preliminary Study","authors":"Hyun Kim, Kang Joon Lee","doi":"10.47825/jkgp.2023.27.2.52","DOIUrl":"https://doi.org/10.47825/jkgp.2023.27.2.52","url":null,"abstract":"Objective: As the elderly population increases, the proportion of neurocognitive disorder is increasing. Accordingly, research on cognitive intervention therapy to prevent neurocognitive disorder is also becoming active. In particular, this study attempted to evaluate changes in cognitive function before and after training and verify their effectiveness by implementing a computerized cognitive training program for patients with mild cognitive impairment.
 Methods: A computerized cognitive training program was conducted for 15 patients with mild cognitive impairment. It was conducted twice a week, 30 minutes, and 16 times for 8 weeks, and neurocognitive function was evaluated before and after training. The neurocognitive function tests are as follows; Seoul Neuropsychological Screening Battery, Korean version of Montreal Cognitive Assessment (K-MoCA), Clinical Dementia Rating (CDR), Korean Instrumental Activity of Daily Living (K-IADL), Korean Neuropsychiatric Inventory (K-NPI), and Memory Age-associated Complaint Questionnaire (MAC-Q).
 Results: There was a statistically significant improvement in memory domain after the implementation of the computerized cognitive training program, but no significant changes in attention, language ability, visuospatial function, and frontal lobe executive function. Among the memory areas, the Seoul Verbal Learning Test: Delayed Recall, Rey Complex Figure Test: Delayed Recall, and Rey Complex Figure Test: Recognition are showed significant improvement. In addition, there was a significant improvement in CDR (sum of box) and K-MoCA scores. There was no statistically significant difference in K-IADL and K-NPI.
 Conclusion: Computerized cognitive training programs have been effective in improving memory in patients with mild cognitive impairment. In order to verify the effectiveness of dementia prevention, a long-term study of a larger number is needed. The results of this preliminary study will help develop and apply cognitive training contents in the future.","PeriodicalId":471642,"journal":{"name":"Noin jeongsin yihag","volume":"97 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135976433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-31DOI: 10.47825/jkgp.2023.27.2.43
Chaelin Joo, Kayoung Kim, Won Hye Lee, Joo Hyun Han, Eunjung Noh, Seon Jin Yim
Objective: The study’s aim was to evaluate the validity of the Korean version of the University of California San Diego Performance- based Skills Assessment, Validation of Intermediate Measures (K-UPSA-2-VIM) in patients with dementia (D), mild cognitive impairment (MCI), and cognitive normal control group (CN). Methods: Study participants were 25 patients with D, 43 patients with MCI, and 111 controls with CN group, respectively. For cognitive assessment, Mini Mental State Examination, Consortium to Establish a Registry for Alzheimer’s Disease neuropsychological battery, and Clinical Dementia Rating were used. For functional assessment, Barthel-Activities of Daily Living, Instrumental Activities of Daily Living, Dementia Screening questionnaire, and K-UPSA-2-VIM were used. Results: Statistically significant differences were observed in all subdomains and total score of the K-UPSA-2-VIM among three cognitive groups. K-UPSA-2-VIM demonstrated 75.7% of sensitivity and 65.1% of specificity, with an area under the curve (AUC) of 0.731 (95% confidence interval [CI]: 0.641-0.821, p<0.001) in discriminating between CN and MCI groups. In discriminating between MCI and D groups, 76.7% of sensitivity and 64.0% of specificity, with an AUC of 0.706 (95% CI: 0.580-0.833, p=0.005) were demonstrated. Conclusion: The K-UPSA-2-VIM is useful to evaluate activities of daily living function in Korean patients with D and MCI.
目的:本研究的目的是评估加州大学圣地亚哥分校基于绩效的技能评估，中间措施验证(K-UPSA-2-VIM)在痴呆(D)、轻度认知障碍(MCI)和认知正常对照组(CN)患者中的效度。方法:研究对象分别为25例D组、43例MCI组和111例对照CN组。认知评估采用迷你精神状态检查、阿尔茨海默病神经心理学研究联盟和临床痴呆评分。功能评估采用Barthel-Activities of Daily Living, Instrumental Activities of Daily Living，痴呆筛查问卷，K-UPSA-2-VIM。
结果:三组间K-UPSA-2-VIM各子域及总分均有统计学差异。K-UPSA-2-VIM鉴别CN组和MCI组的敏感性为75.7%，特异性为65.1%，曲线下面积(AUC)为0.731(95%可信区间[CI]: 0.641-0.821, p<0.001)。鉴别MCI组和D组的敏感性为76.7%，特异性为64.0%，AUC为0.706 (95% CI: 0.580-0.833, p=0.005)。
结论:K-UPSA-2-VIM可用于评价韩国D合并MCI患者的日常生活功能活动。
{"title":"Validation of the Measures for Activities of Daily Living Function: the Korean Version of the University of California San Diego Performance-Based Skills Assessment","authors":"Chaelin Joo, Kayoung Kim, Won Hye Lee, Joo Hyun Han, Eunjung Noh, Seon Jin Yim","doi":"10.47825/jkgp.2023.27.2.43","DOIUrl":"https://doi.org/10.47825/jkgp.2023.27.2.43","url":null,"abstract":"Objective: The study’s aim was to evaluate the validity of the Korean version of the University of California San Diego Performance- based Skills Assessment, Validation of Intermediate Measures (K-UPSA-2-VIM) in patients with dementia (D), mild cognitive impairment (MCI), and cognitive normal control group (CN). Methods: Study participants were 25 patients with D, 43 patients with MCI, and 111 controls with CN group, respectively. For cognitive assessment, Mini Mental State Examination, Consortium to Establish a Registry for Alzheimer’s Disease neuropsychological battery, and Clinical Dementia Rating were used. For functional assessment, Barthel-Activities of Daily Living, Instrumental Activities of Daily Living, Dementia Screening questionnaire, and K-UPSA-2-VIM were used. Results: Statistically significant differences were observed in all subdomains and total score of the K-UPSA-2-VIM among three cognitive groups. K-UPSA-2-VIM demonstrated 75.7% of sensitivity and 65.1% of specificity, with an area under the curve (AUC) of 0.731 (95% confidence interval [CI]: 0.641-0.821, p<0.001) in discriminating between CN and MCI groups. In discriminating between MCI and D groups, 76.7% of sensitivity and 64.0% of specificity, with an AUC of 0.706 (95% CI: 0.580-0.833, p=0.005) were demonstrated. Conclusion: The K-UPSA-2-VIM is useful to evaluate activities of daily living function in Korean patients with D and MCI.","PeriodicalId":471642,"journal":{"name":"Noin jeongsin yihag","volume":"603 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135976267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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