Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery最新文献

Purpose: To compare the surgical outcomes in patients undergoing elective external dacryocystorhinostomy (EX-DCR) and endonasal dacryocystorhinostomy (EN-DCR) for nasolacrimal duct obstruction (NLDO).

Methods and materials: Retrospective non-randomized comparative clinical study. Electronic patient records were used to identify patients that underwent surgery for NLDO from 2013-2019 at Aintree University Hospital, Liverpool. Data regarding the type of operative procedure, patient demographics, preoperative, perioperative, and postoperative examination findings were recorded.

Results: Five hundred and twelve patients underwent DCR surgery (316 EX-DCR and 196 EN-DCR). The EX-DCR cohort median age was 70 (142 males, 176 females), and the EN-DCR median age was 62 (46 males, 149 females). For primary NLDO, symptomatic improvement in treatment-naïve patients was 90.7% (234/258) and 92.2% (141/153), for EX-DCR and EN-DCR, respectively. Revision surgery for failed primary NLDO, was successful in 89.8% (53/59) and 77.3% (34/44), for EX-DCR and EN-DCR respectively. Mean post-operative follow-up was 7.48 months. Complications were rare overall and included epistaxis and granuloma, 1.6% and 2.0%, respectively.

Conclusions: Our overall surgical success rate at 90% (90.5% and 89.3% for EX-DCR and EN-DCR respectively) in primary NLDO are at the higher end of the spectrum of published data. Revision surgery is highly successful, and EX-DCR may be the preferred approach for revision surgery. Younger patients and females were more likely to undergo EN-DCR. Both surgical modalities are safe and complications rare.

Purpose: To evaluate the performance of ChatGPT-4 and Gemini, two large language models (LLMs), in addressing frequently asked questions (FAQs) about eye removal surgeries.

Methods: A set of 24 FAQs related to enucleation and evisceration was identified through a Google search and categorized into preoperative, procedural, and postoperative topics. Each question was submitted three times to ChatGPT-4o and Gemini, and responses were evaluated for consistency, accuracy, appropriateness, and potential harm. Readability was assessed using Flesch Reading Ease and Flesch-Kincaid Grade Level scores.

Results: Gemini exhibited higher response consistency compared to ChatGPT (p = 0.043), while ChatGPT produced longer responses (mean length: 169.3 vs. 109.9 words; p < 0.001). Gemini's responses were more readable, with a higher Flesch Reading Ease score (39.0 vs. 31.3, p = 0.001) and lower Flesch-Kincaid Grade Level (11.6 vs. 14.0, p < 0.001). Both LLMs demonstrated comparable accuracy and low potential for harm, with 79.2% of Gemini responses and 77.1% of ChatGPT responses rated as completely correct. The sources cited by Gemini included academic institutions (91.7%) and medical practices (8.3%), while ChatGPT exclusively referenced academic sources.

Conclusions: ChatGPT and Gemini showed comparable accuracy and low harm potential when addressing patient questions about eye removal surgeries. Gemini provided more consistent and readable responses, but both LLMs exceeded the recommended readability levels for patient education. These findings highlight the potential of LLMs to assist in patient communication and clinical education while underscoring the need for careful oversight in their implementation.

Corynebacterium bovis is principally a zoonotic pathogen and a causative agent of bovine mastitis. To date, there are only 20 documented cases of C. bovis infection in humans in the literature, and only 6 have involved the eye or adnexal structures. No ophthalmologic cases have been demonstrated post-operatively. Here, we present the first case of C. bovis preseptal cellulitis and abscess formation following lower eyelid blepharoplasty. Her infection was difficult to control until microbial susceptibility results became available. The patient made a full recovery from her surgery despite this infection.

Purpose: To present three new cases of primary intraosseous orbital hemangioma (PIOH), including rare lacrimal bone involvement, and to provide an updated systematic review of previously reported cases.

Methods: We retrospectively reviewed three patients with orbital PIOH from our institution. Clinical, radiographic, histopathologic, and surgical findings were analyzed. A comprehensive systematic review of 84 previously published PIOH cases was performed to assess demographics, anatomic location, imaging, and treatment outcomes.

Results: All three patients had firm, progressively enlarging orbital masses. Imaging showed well-circumscribed, expansile lesions confirmed as PIOH histologically. Case 1 involved the zygomatic and sphenoid bones; Case 2, the maxilla and lacrimal bone; and Case 3, the frontal bone. All underwent orbitotomy with subtotal or complete excision and reconstruction. No recurrence was observed at 1-34 month follow-up. In the systematic review, the zygoma (50%) and frontal bone (44%) were most frequently involved. Common symptoms included swelling, proptosis, pain, and globe displacement. CT was the most used imaging modality. Surgical excision, often with preoperative embolization, remains the preferred treatment. Only one recurrence (1.8%) was reported out of the 56 cases with follow-up data.

Conclusions: Orbital PIOH is a rare vascular tumor best managed by tailored surgical excision. Our findings and updated systematic review emphasize individualized planning, particularly in rare sites like the lacrimal bone.

Purpose: To provide Australian data and a literature review on the clinical, radiological, and microbiological features and outcomes in patients with orbital abscess secondary to dacryocystitis.

Methods: Multicentre retrospective review of orbital abscess secondary to acute dacryocystitis from 2019 to 2024 in Australia.

Results: Eight cases were identified. The median age was 56 years (range, 26-80 years) with no gender predilection. Common presenting symptoms and signs were motility restriction (n  = 6, 75%), proptosis (n = 5, 62.5%), decreased visual acuity (n = 4, 50%), chemosis (n  = 3, 37.5%) and RAPD (n = 2, 25%). Radiologically inferomedial (n  = 3, 37.5%) and medial (n  = 2, 25%) orbital involvement was most commonly followed by intraconal (n = 2, 25%) and inferior (n = 1, 12.5%) orbit. Microbiological cultures revealed gram-negative bacteria (n = 3), gram-positive bacteria (n  = 1), anaerobic growth (n = 1), polymicrobial growth (n  = 1), MRSA (n = 1), and no growth (n = 1). Treatment included intravenous antibiotics in all cases, 4 patients underwent orbital abscess drainage combined with DCR, 1 had orbital drainage alone, 1 had endoscopic DCR alone, 1 had canthotomy with cantholysis, and 1 patient did not receive surgical treatment. One patient lost vision (light perception) with remainder having stable or improved visual acuity at follow up.

Conclusion: Acute surgical management needs to be considered in majority of cases with dacryocystitis and orbital abscess. Signs of orbital involvement in acute dacryocystitis should be identified promptly to prevent irreversible visual loss.

Eyelid and conjunctiva sparing exenteration (ECSE) allows for the extirpation of pathologies that lie deep within the orbit without disrupting the anatomy of the eyelids. Despite the cosmetic benefits of maintaining the eyelids, few cases of ECSE have been reported, and reconstruction following the procedure has only been detailed in the form of primary closure or a temporalis muscle transfer. The authors present two patients with deep orbital pathologies that extended into the intracranial space. Each patient underwent an extended ECSE followed by reconstruction with a microvascular free flap. The combination of ECSE plus microvascular free flap reconstruction offers an alternative approach to previously published techniques and may improve esthetic outcomes when exenteration is required for deep orbital pathologies.

Purpose: To compare the clinical presentation, imaging features and outcomes of patients with orbital myositis (OM) and thyroid associated orbitopathy (TAO).

Methods: A retrospective and comparative study of 60 patients diagnosed with OM in a tertiary Eye Clinic between 2012 and 2023. Cases were matched with 60 TAO controls by sex and age.

Results: Clinical presentation of OM differs from TAO with a unilateral involvement and an acute onset of symptoms in 93% and 65% of cases, respectively. OM usually affect a single extraocular muscle (63%), typically the medial rectus, whereas TAO affect multiple and several EOM, with higher incidence of increased orbital fat volume. Tendon sparing on MRI was not discriminant between both conditions. Patients with OM had a better remission rate at 12 months (48% vs 14%, p < 0.001). Optic neuritis occurred in only one patient with OM vs. 11 patients with TAO (p < 0.001) and 12 patients had a relapse of OM with a contralateral involvement in 3/12 patients (25%).

Conclusions: This comparative study highlights key clinical and imaging features that distinguish OM from TAO. OM is associated with a better clinical outcome and prognosis with a reduced risk of optic neuritis and relapse compared with TAO patients.

Inverse Bell's phenomenon (IBP) is a rare but clinically significant complication of eyelid surgery, characterized by paradoxical downward deviation of the globe during attempted eyelid closure. This study presents a retrospective case series of four patients who developed IBP within three months after upper eyelid surgery at a tertiary oculoplastic center (2018-2024) together with a review of the literature. Presentations ranged from transient IBP that resolved spontaneously to persistent cases associated with lagophthalmos or ocular surface disease. Two patients regained a normal Bell's reflex after conservative or surgical management, whereas two developed chronic IBP despite intervention. Literature review indicates that most cases are transient, although persistent IBP may result from scarring, fibrosis, or neuromuscular disruption. Careful preoperative assessment of Bell's reflex, close postoperative monitoring, and early individualized management are essential. While most cases resolve without sequelae, persistent IBP may necessitate surgical intervention and carries a risk of long-term ocular surface morbidity.

Purpose: To analyze the correlation between a magnetic resonance imaging (MRI) score, we proposed in a previous report, and conventional quantitatively evaluated MRI findings, and to evaluate the clinical utility of the MRI score in patients with Graves' ophthalmopathy (GO).

Methods: Using ImageJ, we retrospectively re-analyzed magnetic resonance images of 25 patients with GO who were evaluated in the previous study. The signal intensity and area measured by ImageJ were normalized for each affected extraocular muscle (EOM) in each patient (normalized quantified inflammation and enlargement). Furthermore, the ratio of the value for the affected EOM to the normal values was calculated in each patient (quantified inflammation and enlargement compared to normal values). We analyzed the correlations between MRI scores and quantitative MRI finding before and after 6 g of intravenous methylprednisolone (IVMP).

Results: The correlation coefficient between the normalized MRI score and normalized quantified inflammation and enlargement was 0.59 before IVMP and 0.69 after IVMP. The correlation coefficient between the MRI score and quantified inflammation and enlargement compared to normal values was 0.58 before IVMP and 0.73 after IVMP. The correlation coefficients for all items were statistically significant (P-value < .05).

Conclusion: This study found a high correlation between the MRI score, which is our proposed semiquantitative method for assessing EOM swelling and inflammation, and the results of conventional quantitative evaluation methods. This suggests that the MRI score, which can be more readily used in clinical practice, may be as reliable as quantitative evaluation methods.