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Personal Hygiene and Environmental Sanitation Factors that Influence the Incidence of Scabies in Al-Bayan 影响巴彦地区疥疮发病率的个人卫生和环境卫生因素
Pub Date : 2024-06-04 DOI: 10.33096/gmj.v6i1.153
Abrar Ghifari Hasti, Dian Amelia Abdi, Zulfiyah Surdam, Nurfachanti Fattah, Lisa Yuniati
Introduction: The scabies is a skin disease caused by an infestation of Sarcoptes scabies mites. The scabies prevalence in Makassar city health profile in 2012 was 8 of 10 major diseases with a huge 6.63 %. Methods: Analytical description with cross-sectional design. Data was collected through interviews using personal hygiene questionnaires and environmental sanitation observation sheets.  The sample for this study was total sampling, a total of 67 junior high school Al Bayan Hidayatullah students were selected. Results: Chi-square test results that showed that there was a relationship between skin hygiene and the incidence of scabies (p-value = 0.000), there was a relationship between hand hygiene and the incidence of scabies (p-value = 0.014), there was a relationship between nail hygiene and the incidence of scabies (p-value = 0.023), there is a relationship between clothing hygiene and the incidence of scabies (p-value = 0.000), there is a relationship between towel hygiene and the incidence of scabies (p-value = 0.006), there is no relationship between bed and bed linen hygiene and the incidence of scabies (p-value = 0.095 ), There is no relationship between environmental sanitation and the incidence of scabies (p-value = 0.538), There is no relationship between residential density and the incidence of scabies (p-value = 0.538). Conclusion: Improve personal hygiene and improve environmental sanitation so that they can avoid scabies as early as possible.
简介疥疮是一种由疥螨寄生引起的皮肤病。2012 年,在望加锡市健康档案中,疥疮发病率在 10 种主要疾病中占 8 种,高达 6.63%。研究方法采用横断面设计进行分析描述。通过个人卫生问卷和环境卫生观察表进行访谈收集数据。 研究样本为总体抽样,共选取了 67 名 Al Bayan Hidayatullah 初级中学的学生。研究结果Chi-square 检验结果表明,皮肤卫生与疥疮发病率之间存在关系(P 值 = 0.000),手部卫生与疥疮发病率之间存在关系(P 值 = 0.014),指甲卫生与疥疮发病率之间存在关系(P 值 = 0.023),衣物卫生与疥疮发病率之间存在关系(P 值 = 0.000),毛巾卫生与疥疮发病率有关系(P 值 = 0.006),床和床单卫生与疥疮发病率没有关系(P 值 = 0.095 ),环境卫生与疥疮发病率没有关系(P 值 = 0.538),居住密度与疥疮发病率没有关系(P 值 = 0.538)。结论改善个人卫生和环境卫生,以便尽早避免疥疮的发生。
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引用次数: 0
Effect of Dangke on Changes in Neutrophil to Lymphocyte Ratio in Obese White Rats 当可对肥胖白鼠中性粒细胞与淋巴细胞比率变化的影响
Pub Date : 2024-06-04 DOI: 10.33096/gmj.v6i1.158
Alya Muthia Nur Amari Natsar, Asrini Safitri, Rezky Pratiwi L Basri, Sri Julyani, I. D. Kartika
Introduction: Obesity is associated with inflammation. Previous research has found that obesity determined by Body Mass Index (BMI) and Waist Circumference (LP) is associated with inflammation. Dangke contains Indigenos Lactic Acid Bacteria. The presence of lactic acid bacteria in fermented products has very positive benefits for health. The function of papaya sap which is used in making dangke, can act as an antibacterial and anti-inflammatory ingredient. Methods: Pure experimental research with a design, namely Pre-Post Randomized Clinical Trial Design. Data analysis used the independent T-test/Mann-Whitney test with a value <0.05. Results: The difference in the mean levels of Neutrophil to Lymphocyte (NLR) in the Intervention and control groups obtained a p-value of 0.94 which means that there is no relationship between control and intervention on NLR levels. The average change in NLR levels in the control group p-value of 0.61 which means there is no significant change in NLR levels in test 1 and test 2. The average change in NLR levels in the intervention group before and after the intervention was given a p-value of 0.07, which means there was no significant change in NLR levels in the intervention group. Conclusion: This study showed that intervention with Dangke did not yield a significant alteration in the NLR levels within the animal model of obesity.
导言肥胖与炎症有关。以往的研究发现,根据体重指数(BMI)和腰围(LP)确定的肥胖与炎症有关。Dangke 含有 Indigenos 乳酸菌。发酵产品中的乳酸菌对健康非常有益。用于制作当归的木瓜汁液可作为抗菌消炎成分。研究方法纯实验研究设计,即前-后随机临床试验设计。数据分析采用独立 T 检验/曼-惠特尼检验,检验值小于 0.05。结果干预组和对照组的中性粒细胞对淋巴细胞(NLR)平均水平的差异得出的 P 值为 0.94,这意味着对照组和干预组在 NLR 水平上没有关系。对照组 NLR 水平的平均变化 p 值为 0.61,这意味着 NLR 水平在测试 1 和测试 2 中没有显著变化。 干预组 NLR 水平在干预前后的平均变化 p 值为 0.07,这意味着干预组 NLR 水平没有显著变化。结论这项研究表明,在肥胖症动物模型中,使用 Dangke 进行干预并没有使 NLR 水平发生显著变化。
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引用次数: 0
Biliary Atresia with Cytomegalovirus Infection, Congenital Heart Disease and Pneumonia: A Case Report 胆道闭锁伴巨细胞病毒感染、先天性心脏病和肺炎:病例报告
Pub Date : 2024-06-04 DOI: 10.33096/gmj.v6i1.137
Gracia Dewi, Setia Budi Salekede, Sri Hardiyanti Putri, Ninny Meutia Pelupessy, Mokhammad Ikhsan, Amiruddin Laompo
Biliary atresia (BA) is a condition of biliary obstruction. Kasai portoenterostomy (KPE) is a treatment option. The aim to determine the success rate of kasai procedure and prognosis in BA patients with other underlying diseases. This is a descriptive case study research. We report a boy, 2 months and 11 days with jaundice all over his body since one week old; putty stool, and dark urine. Old man's face, icteric, rib xylophone, subcostal retraction, rales, continuous heart murmur, and wasting. Total and direct bilirubin, SGOT, SGPT, and gamma GT are increased. A Kasai surgical procedure was carried out, but did not significantly improve his condition because the operation was performed at the age of 4 months and 8 days with liver cirrhosis, sepsis, pneumonia, and malnutrition. Cytomegalovirus (CMV) infection and acyanotic congenital heart disease also worsened his preoperative condition. Kasai portoenterostomy is a method of managing biliary atresia, but our patient was diagnosed with biliary atresia accompanied by CMV infection, congenital heart disease, or pneumonia, so the procedures not enough for this condition, and mortality rate is higher than biliary atresia alone. Age at surgery time also influences the prognosis.
胆道闭锁(BA)是一种胆道梗阻疾病。葛西肠管造口术(KPE)是一种治疗方法。本研究旨在确定伴有其他基础疾病的胆道闭锁患者接受 Kasai 手术的成功率和预后。这是一项描述性病例研究。我们报告了一名 2 个月零 11 天的男孩,从一周大起全身黄疸,大便呈腻子状,小便颜色深。老人面容,黄疸,肋骨木琴状,肋下回缩,啰音,持续性心脏杂音,消瘦。总胆红素、直接胆红素、SGOT、SGPT 和γ GT 增高。虽然进行了卡萨伊手术,但并没有明显改善他的病情,因为手术是在他 4 个月零 8 天时进行的,当时他患有肝硬化、败血症、肺炎和营养不良。巨细胞病毒(CMV)感染和急性先天性心脏病也加重了他的术前状况。葛西肠管造口术是治疗胆道闭锁的一种方法,但我们的患者被诊断为胆道闭锁,同时伴有巨细胞病毒感染、先天性心脏病或肺炎,因此该手术并不适合这种情况,而且死亡率比单纯的胆道闭锁更高。手术时的年龄也会影响预后。
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引用次数: 0
Association of Nutritional Intake and Toddler Development 营养摄入与幼儿发展的关系
Pub Date : 2023-08-31 DOI: 10.33096/gmj.v5i2.146
Risky Awalia H, Rosdianah Rahim, Arlina Wiyata Gama, Abdul Rahman
Introduction: This study explores the impact of nutritional intake on the growth and development of children, particularly in terms of brain development during the toddler phase. The objective was to establish a link between nutritional intake and children's development. Methods: This research employs a quantitative approach, utilizing an analytical survey design with a crosssectional methodology. The research tools consisted of a developmental pre-screening questionnaire and a Food Frequency Questionnaire (FFQ). The sample included 74 children aged 1 to 3 years, who were attendees of the Bulukunyi Health Center in Takalar Regency. The data analysis was conducted using the Chi Square test, with statistical significance set at p < 0.05. Results: The study unveiled noteworthy correlations between protein intake (p = 0.013), vitamin A (p = 0.019), and vitamin C (p = 0.011) and the growth and development of children. Conclusion: This research establishes a positive connection between protein intake, as well as the intake of vitamin C and vitamin A, and the development of children during the toddler phase.
本研究探讨了营养摄入对儿童生长发育的影响,特别是在幼儿阶段的大脑发育方面。目的是建立营养摄入与儿童发育之间的联系。方法:本研究采用定量方法,利用横断面方法的分析性调查设计。研究工具包括发育前筛选问卷和食物频率问卷(FFQ)。样本包括74名1至3岁的儿童,他们是塔克拉拉尔摄政区Bulukunyi卫生中心的参与者。数据分析采用卡方检验,p <为统计学显著性;0.05. 结果:该研究揭示了蛋白质摄入量(p = 0.013)、维生素A (p = 0.019)、维生素C (p = 0.011)与儿童生长发育之间值得注意的相关性。结论:本研究建立了蛋白质摄入量以及维生素C和维生素a的摄入量与幼儿期儿童发育之间的正相关关系。
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引用次数: 0
Polycythemia Vera: A Malignancy in Hematology: Review Article 真性红细胞增多症:血液学中的一种恶性肿瘤:综述文章
Pub Date : 2023-08-31 DOI: 10.33096/gmj.v5i2.117
Shafalyn Roliskana, Devi Rahmadhona
ABSTRACT: Myeloid neoplasm is a condition in which myeloid cells can undergo excessive clonal proliferation. One classification of the disease is polycythemia vera.Polycythemia Vera (PV) is a condition where there is an increase in the number of red blood cells reaching 125% of the calculation based on body mass and sex. PV is caused by mutations in the JAK2 gene. PV disease diagnosisBased on the results of the history, physical examination and supporting examinations in the form of laboratory tests. PV disease can be managed with phlebotomy, administration of aspirin, and cytoreductive drugs. Patients with PV can survive more than 10 years if treated quickly and appropriately.
摘要:髓系肿瘤是一种髓系细胞可发生过度克隆增殖的疾病。该疾病的一种分类是真性红细胞增多症。真性红细胞增多症(PV)是红细胞数量增加达到按体重和性别计算的125%的一种疾病。PV是由JAK2基因突变引起的。PV病诊断依据病史、体格检查和实验室检查形式的辅助检查结果。PV疾病可以通过静脉切开术、阿司匹林和细胞减少药物治疗。如果治疗迅速和适当,PV患者可以存活10年以上。
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引用次数: 0
Inspiratory Muscle Training in Chronic Obstructive Pulmonary Disease Patients: A Scoping Review 慢性阻塞性肺疾病患者的吸气肌训练:范围综述
Pub Date : 2023-08-31 DOI: 10.33096/gmj.v5i2.144
Imran Safei, Zulfahmidah Zulfahmidah
Introduction: COPD is a leading cause of chronic disease and death globally, with high mortality rates for those hospitalized or requiring mechanical ventilation. Delaying disease progression and improving patient outcomes can reduce healthcare costs and societal impact. Respiratory muscles play a crucial role in COPD, and specific endurance respiratory exercises have been shown to improve muscle fibers and mitochondrial activity, reducing oxidative stress and fatigue. Inspiratory Muscle Training (IMT) is a recommended pulmonary rehabilitation technique that enhances lung capacity and improves exercise performance by altering muscle fiber types and distribution. The impact of IMT implemented in COPD remains unclear. This scoping review aims to ascertain the impact IMT has on COPD patients. Methods: A scoping review was performed in PubMed, Academic Search Complete/EBCSCO, and Grey Literature sources, including Google Scholar. IMT studies evaluating interventions for COPD patients that were published in 2018-2023 were included. Results: We reviewed 644 studies, nine IMT interventions met inclusion criteria and were included in the current study. In the majority of studies, improvements were noted through the implementation of IMT interventions. Several facilitators and barriers were noted during implementation and contributed to the success or failure of the intervention. Conclusion: Overall, IMT had conflicting effects on a variety of COPD patient outcomes. Numerous studies demonstrate, however, that IMT can improve COPD-related outcomes, such as respiratory muscle function, dyspnea symptoms, quality of life, autonomic function, exercise tolerance, diaphragmatic strength and reduced exertional dyspnea, and balance.
慢性阻塞性肺病是全球慢性疾病和死亡的主要原因,住院或需要机械通气的患者死亡率很高。延缓疾病进展和改善患者预后可以降低医疗成本和社会影响。呼吸肌在慢性阻塞性肺病中起着至关重要的作用,特定的耐力呼吸运动已被证明可以改善肌肉纤维和线粒体活动,减少氧化应激和疲劳。吸气肌训练(IMT)是一种推荐的肺部康复技术,通过改变肌肉纤维的类型和分布来增强肺活量和改善运动表现。在COPD中实施IMT的影响尚不清楚。本综述旨在确定IMT对COPD患者的影响。方法:在PubMed、Academic Search Complete/EBCSCO和灰色文献来源(包括Google Scholar)中进行范围综述。纳入2018-2023年发表的评估COPD患者干预措施的IMT研究。 结果:我们回顾了644项研究,其中9项IMT干预符合纳入标准,并被纳入本研究。在大多数研究中,通过实施IMT干预措施可以注意到改善。在实施过程中注意到一些促进因素和障碍,这些因素对干预措施的成功或失败起了一定的作用。结论:总体而言,IMT对多种COPD患者预后的影响相互矛盾。然而,大量研究表明,IMT可以改善copd相关结局,如呼吸肌功能、呼吸困难症状、生活质量、自主神经功能、运动耐量、膈肌力量和减轻的用力性呼吸困难,以及平衡。
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引用次数: 0
Sensitive Molecular Detection for Salmonella Enterica Serovars Typhimurium 肠炎沙门氏菌血清型鼠伤寒沙门氏菌的灵敏分子检测
Pub Date : 2023-08-31 DOI: 10.33096/gmj.v5i2.145
Hasta Handayani Idrus, Sarwo Handayni, Fitriana Fitriana
Introduction: Salmonella infections contribute significantly to gastroenteritis cases, with the National Salmonella Reference Laboratory reporting 500 isolates in 2022. However, traditional culture-based methods for detecting Salmonella in samples can take 4 to 7 days to confirm a positive result, which poses health risks due to delayed detection. Given these health risks, swift and accurate detection methods are essential to minimize both false-positive and false-negative outcomes. Salmonella, a gram-negative bacterium within the Enterobacteriaceae family, demonstrates remarkable hardiness, surviving for several weeks in dry environments and months in water. Although most serotypes of Salmonella cause relatively mild gastroenteritis, some, particularly those transmitted from animals to humans, can lead to severe, life-threatening conditions Methods: The qRT-PCR procedure involved the design of primers and probes targeting the same genes as the mPCR assay. These primer sets were reconfigured to generate smaller amplicons suitable for qRT-PCR systems Results: qRT-PCR process, TaqMan probes were meticulously designed for specific target genes: FAM dye was employed to detect STM2745, Cy5 dye was used for STM4492, and Rox dye was utilized to detect. A standard curve was constructed using Typhimurium LT2 genomic DNA. Each sample underwent duplicate analysis, and Rotor-Gene software was employed to assign threshold values for each channel. Conclusion: The effectiveness of our qPCR assay for the detection of Salmonella across a diverse array of matrices. Notably, our results unveiled distinct limits of detection for Salmonella in various samples. Specifically, a parallel vein, the deployment of a PCR assay, leveraging an immunomagnetic separation technique for DNA extraction, was studied by another group. While subsequent analysis of Salmonella detected via our assay may necessitate the full ISO SMT method for live culture isolation, this supplementary step can be seamlessly conducted alongside qRT-PCR.
简介:沙门氏菌感染是肠胃炎病例的重要原因,国家沙门氏菌参考实验室在2022年报告了500个分离株。然而,传统的基于培养的检测样本沙门氏菌的方法可能需要4至7天才能确认阳性结果,这由于检测延迟而构成健康风险。鉴于这些健康风险,快速和准确的检测方法对于最大限度地减少假阳性和假阴性结果至关重要。沙门氏菌是肠杆菌科的一种革兰氏阴性细菌,它表现出非凡的耐寒性,在干燥环境中存活数周,在水中存活数月。虽然大多数血清型沙门氏菌引起相对轻微的胃肠炎,但有些,特别是那些从动物传播给人类的沙门氏菌,可导致严重的、危及生命的疾病 方法:qRT-PCR程序涉及的引物和探针的设计针对相同的基因的mPCR试验。这些引物组被重新配置以产生适合于qRT-PCR系统的更小的扩增子 结果:qRT-PCR工艺中,针对特定靶基因精心设计了TaqMan探针:STM2745采用FAM染料检测,STM4492采用Cy5染料检测,Rox染料检测。用鼠伤寒杆菌LT2基因组DNA构建标准曲线。每个样本进行重复分析,并使用Rotor-Gene软件为每个通道分配阈值。 结论:我们的qPCR检测方法在多种基质中检测沙门氏菌是有效的。值得注意的是,我们的结果揭示了不同样品中沙门氏菌的明显检测限。具体而言,另一组研究了平行静脉,利用免疫磁分离技术进行DNA提取的PCR测定的部署。虽然通过我们的实验检测到的沙门氏菌的后续分析可能需要完整的ISO SMT方法进行活培养分离,但这一补充步骤可以与qRT-PCR无缝地进行。
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引用次数: 0
Risk Factor Analysis of Anxiety Disorder in Third Trimester Pregnant Women 妊娠晚期孕妇焦虑障碍的危险因素分析
Pub Date : 2023-08-31 DOI: 10.33096/gmj.v5i2.143
Reski Nursyifah, Dewi Setiawati, Rista Suryaningsih
Introduction: Pregnancy is a natural thing for productive women. Anxiety that occurs in pregnancy is an emotional response related to the concern felt by the mother for the well-being of herself and her fetus during pregnancy, childbirth and the role of being a mother later. The purpose of this study was to determine the relationship between age, level of education, occupation, economy, parity, environmental status, and religious spiritual activities on anxiety disorders in third trimester pregnant women in Somba Opu District, Gowa Regency. Methods: The instrument in this study used a questionnaire. The sample used in this study consisted of 136 third trimester pregnant women in the work area of ​​Syekh Yusuf Hospital and Sungguminasa Health Center. Data was processed and analyzed as needed and data analysis using Chi Square test p<0.05 Results: The study showed that there was a significant relationship between age, education level, occupation, economic factors, parity, and religious spiritual activities with anxiety disorder levels in third trimester pregnant women and this study did not show that there was a significant relationship between living environment status. with the level of anxiety disorder in third trimester pregnant women (0.514) Conclusion: There is a relationship between age, education level, occupation, economic factors, parity, and religious spiritual activities with anxiety disorder levels in third trimester pregnant women, and there is no relationship between living environment status and anxiety disorder levels in third trimester pregnant women.
导读:怀孕对生育能力强的女性来说是一件很自然的事情。怀孕期间出现的焦虑是一种情绪反应,与母亲在怀孕期间、分娩期间以及以后作为母亲的角色对自己和胎儿的健康的担忧有关。本研究的目的是确定年龄、教育水平、职业、经济、平等、环境状况和宗教精神活动与Gowa县Somba Opu区妊娠晚期孕妇焦虑症之间的关系。方法:本研究采用问卷调查法。本研究中使用的样本包括在Syekh Yusuf医院和Sungguminasa健康中心工作区域的136名妊娠晚期孕妇。根据需要对数据进行处理和分析,数据分析采用卡方检验p<0.05 & # x0D;结果:本研究显示,年龄、受教育程度、职业、经济因素、胎次、宗教精神活动与孕晚期孕妇焦虑障碍水平有显著相关,而本研究未显示生活环境状况与焦虑障碍水平有显著相关。与妊娠晚期孕妇焦虑障碍水平(0.514) 结论:年龄、受教育程度、职业、经济因素、胎次、宗教精神活动与妊娠晚期孕妇焦虑障碍水平存在相关性,而生活环境状况与妊娠晚期孕妇焦虑障碍水平无相关性。
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引用次数: 0
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