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Comprehensive clinical outcomes of TiRobot-assisted minimally invasive surgery for pelvic fractures: a meta-analysis. tirobot辅助微创手术治疗骨盆骨折的综合临床结果:一项荟萃分析
IF 3 3区 医学 Q2 SURGERY Pub Date : 2026-02-03 DOI: 10.1007/s11701-026-03212-z
Yifan Yin, Guohang Shen, Ruoyan Wang, Huiling Chen, Kaiyong Wang, Yang Chen, Yupei Dai

Pelvic fractures, often caused by high-energy trauma, represent a significant challenge in orthopaedic practice. TiRobot-assisted minimally invasive surgery has emerged as a promising alternative, offering precise and navigated percutaneous fixation. However, robust evidence comparing its clinical efficacy with traditional methods is limited. This meta-analysis systematically reviewed studies comparing TiRobot-assisted surgery with conventional surgical techniques for pelvic fractures. Databases including PubMed, Web of Science, Embase, and the Cochrane Library were searched for studies published until December 1, 2025. Eleven studies, including randomized controlled trials (RCTs) and cohort studies, were included. Primary outcomes assessed were perioperative parameters, functional recovery, safety, and healthcare costs. Pooled analyses showed that TiRobot-assisted surgery was significantly associated with shorter operative times, lower intraoperative blood loss, fewer fluoroscopic exposures, and fewer drilling attempts compared with conventional surgery. Additionally, the TiRobot-assisted group demonstrated a lower screw malposition rate and reduced overall complication rates. Functional outcomes, measured by Majeed pelvic scores, were superior in the TiRobot-assisted group. However, direct medical costs were higher for TiRobot-assisted surgery. In conclusion, TiRobot-assisted surgery offers substantial advantages in managing pelvic fractures, optimizing perioperative efficiency, screw placement accuracy, and functional recovery, while reducing complications. Despite higher initial costs, TiRobot-assisted surgery presents a highly valuable minimally invasive option, particularly for complex and unstable pelvic fractures.

骨盆骨折通常由高能创伤引起,是骨科实践中的一个重大挑战。tirobot辅助的微创手术已经成为一种很有前途的选择,提供精确和导航的经皮固定。然而,将其临床疗效与传统方法进行比较的有力证据有限。本荟萃分析系统回顾了比较tirobot辅助手术与传统手术技术治疗骨盆骨折的研究。检索了PubMed、Web of Science、Embase和Cochrane Library等数据库,检索了截至2025年12月1日发表的研究。纳入11项研究,包括随机对照试验(rct)和队列研究。评估的主要结果是围手术期参数、功能恢复、安全性和医疗费用。综合分析显示,与传统手术相比,tirobot辅助手术与更短的手术时间、更低的术中出血量、更少的透视暴露和更少的钻孔尝试显著相关。此外,tirobot辅助组表现出较低的螺钉错位率和降低的总体并发症发生率。通过Majeed骨盆评分测量的功能结果在tirobot辅助组中更好。然而,tirobot辅助手术的直接医疗费用更高。总之,tirobot辅助手术在治疗骨盆骨折、优化围手术期效率、螺钉放置准确性和功能恢复方面具有显著优势,同时减少并发症。尽管初始成本较高,但tirobot辅助手术提供了一种非常有价值的微创选择,特别是对于复杂和不稳定的骨盆骨折。
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引用次数: 0
Robot assisted compared to conventional knee arthroplasty: metanalysis and systematic review. 机器人辅助与传统膝关节置换术的比较:荟萃分析和系统回顾。
IF 3 3区 医学 Q2 SURGERY Pub Date : 2026-02-03 DOI: 10.1007/s11701-026-03172-4
Zaid Khalaf, Asem Rahahleh, Omar Al-Amairah

Robot-assisted total knee replacement has emerged as a promising technology in bone surgery, offering further precision and accuracy compared to manual methods. This advancement shows potential benefits for better patient outcomes. The PRISMA 2020 guidelines were followed to ensure a transparent, systematic, and reproducible evaluation of all included studies. This method helped review research properly. Comparative studies and controlled trials related to robot-assisted knee arthroplasty compared to conventional knee arthroplasty were found using multiple database searching (PubMed/MEDLINE, Embase, Cochrane Library, and Web of Science). The search strategy enabled identification of relevant studies. The study showed that robotic knee surgery had significantly better post-operative anatomical and mechanical restoration compared to the regular surgery methods. However, clinical and functional results were similar between both groups, and the complication rates themselves showed no further difference. Robot-assisted knee replacement surgery showed better accuracy and fewer alignment problems compared to conventional manual TKA. Regarding short-term results, patients had better outcomes with robot-assisted methods. Total Knee Arthroplasty itself became cost-effective when case volume was further increased beyond 49 cases per year. Although Robot-assisted knee surgery provides better accuracy in component positioning and alignment, the actual patient outcomes and knee function remain comparable to traditional surgery methods in short and medium-term follow-up. The technology shows promise; however, longer-term studies are required to determine whether these improvements translate into superior clinical outcomes. The cost-effectiveness only depends on how many cases the hospital manages and how well they organize their work processes.

机器人辅助全膝关节置换术在骨外科手术中已经成为一项很有前途的技术,与人工方法相比,它提供了更高的精确度和准确性。这一进步显示了潜在的好处,可以改善患者的预后。遵循PRISMA 2020指南,以确保对所有纳入的研究进行透明、系统和可重复的评估。这种方法有助于正确地审查研究。通过多个数据库检索(PubMed/MEDLINE、Embase、Cochrane Library和Web of Science),发现机器人辅助膝关节置换术与传统膝关节置换术相关的比较研究和对照试验。搜索策略可以识别相关研究。研究表明,与常规手术方法相比,机器人膝关节手术具有明显更好的术后解剖和机械恢复。然而,两组的临床和功能结果相似,并发症发生率本身无进一步差异。与传统的人工膝关节置换术相比,机器人辅助的膝关节置换术显示出更好的准确性和更少的对齐问题。就短期效果而言,采用机器人辅助方法的患者效果更好。当病例数量进一步增加到每年49例以上时,全膝关节置换术本身就具有成本效益。尽管机器人辅助膝关节手术在部件定位和对齐方面提供了更好的准确性,但在中短期随访中,患者的实际预后和膝关节功能仍与传统手术方法相当。这项技术显示了前景;然而,需要更长期的研究来确定这些改善是否转化为更好的临床结果。成本效益只取决于医院管理了多少病例以及他们如何组织他们的工作流程。
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引用次数: 0
Impact of an intraoperative Trendelenburg break on perioperative outcomes during robot-assisted radical prostatectomy. 术中Trendelenburg断裂对机器人辅助根治性前列腺切除术围手术期预后的影响。
IF 3 3区 医学 Q2 SURGERY Pub Date : 2026-02-03 DOI: 10.1007/s11701-026-03160-8
Arnold R Palacios, Jack Rausch, Quentin H Drane, Lester Hubble, Dane E Klett
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引用次数: 0
Correction: Computed tomography versus long-leg radiography for CPAK-based coronal alignment assessment in total knee arthroplasty: a prospective evaluation. 纠正:计算机断层扫描与长腿x线摄影在全膝关节置换术中基于cpap的冠状位评估:一项前瞻性评估。
IF 3 3区 医学 Q2 SURGERY Pub Date : 2026-02-02 DOI: 10.1007/s11701-026-03175-1
Anoop Jhurani, Sanchay Lavaniya, Gaurav Ardawatia, Piyush Agarwal, Abhishek Dwivedi, Mudit Srivastava
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引用次数: 0
Effect of combined acetaminophen and nefopam on postoperative pain in patients undergoing robot-assisted urological surgery: a retrospective propensity score-matched analysis. 对乙酰氨基酚联合奈福泮对机器人辅助泌尿外科手术患者术后疼痛的影响:回顾性倾向评分匹配分析。
IF 3 3区 医学 Q2 SURGERY Pub Date : 2026-01-31 DOI: 10.1007/s11701-025-03013-w
Soowon Lee, Jung-Hee Ryu, Young-Tae Jeon, Ah-Young Oh, Chang-Hoon Koo

The acetaminophen-nefopam combination has not been investigated as a preventive analgesic strategy for robot-assisted urological surgery. Here, we evaluated whether their administration could reduce postoperative pain and opioid consumption in such patients. This retrospective cohort study analyzed adults who underwent robot-assisted urological surgery from April 2023 to March 2025 at a single tertiary academic center. Patients received conventional anesthetic management (conventional group) or preventive acetaminophen (1000 mg) and nefopam (20 mg) at robotic system de-docking (preventive group). Propensity score matching (1:1) was performed using the ASA physical performance class, surgery type, surgeon, and procedure duration. Pain was assessed using an 11-point numeric rating scale. The primary outcome was pain severity distribution upon postanesthesia care unit (PACU) arrival. After matching, 340 patients (170 per group) were analyzed. The preventive group exhibited higher proportions of patients with no/mild pain (57.6% vs. 29.4%, P < 0.001) and lower proportions with moderate pain (20.0% vs. 40.6%, P < 0.001) compared to the conventional group. Opioid-free analgesia rates were higher in the preventive group during PACU stay (36.5% vs. 16.5%, P < 0.001) and in the first 24 h (30.6% vs. 13.5%, P < 0.001). Rescue opioid consumption was lower in the preventive group during the PACU (2.5 vs. 7.5 mg morphine equivalent, P < 0.001) and 24-h periods (5 vs. 10 mg, P < 0.001). Their PACU stay was also shorter (34 vs. 40.5 min, P < 0.001). Preventive acetaminophen-nefopam administration was associated with significantly lower postoperative pain severity and opioid requirements and faster recovery after robot-assisted urological surgery.

对乙酰氨基酚-奈福泮联合应用作为机器人辅助泌尿外科手术的预防性镇痛策略尚未进行研究。在这里,我们评估了给药是否可以减少这类患者的术后疼痛和阿片类药物的消耗。本回顾性队列研究分析了2023年4月至2025年3月在一个三级学术中心接受机器人辅助泌尿外科手术的成年人。患者在机器人系统分离时接受常规麻醉管理(常规组)或预防性对乙酰氨基酚(1000 mg)和奈福泮(20 mg)(预防组)。倾向评分匹配(1:1)采用ASA身体表现等级、手术类型、外科医生和手术持续时间进行。疼痛采用11分的数字评定量表进行评估。主要结局是麻醉后护理单位(PACU)到达时的疼痛严重程度分布。匹配后,340例患者(每组170例)进行分析。预防组患者无/轻度疼痛的比例更高(57.6% vs. 29.4%, P
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引用次数: 0
Da Vinci platform robotic adrenalectomy for adrenal neoplasms: a GRADE-assessed systematic review and meta-analysis of prospective randomized trials comparing perioperative, postoperative, and economic outcomes with laparoscopic adrenalectomy. 达芬奇平台机器人肾上腺切除术治疗肾上腺肿瘤:一项分级评估的前瞻性随机试验的系统评价和荟萃分析,比较了腹腔镜肾上腺切除术的围手术期、术后和经济结果。
IF 3 3区 医学 Q2 SURGERY Pub Date : 2026-01-31 DOI: 10.1007/s11701-026-03204-z
Wajahat Mirza, Fahad Khan Orakzai, Rao Nouman Ali, Mehak Ejaz Khan, Muhammad Bilal Moeen-Ud-Din, Hania Iqbal, Alishbah Khan, Abdul Rahim Khan, Hadi Mohammad Khan

Robot-assisted adrenalectomy using the da Vinci platform offers theoretical advantages over conventional laparoscopy, including enhanced visualization, superior instrument articulation, and improved ergonomics. However, their comparative effectiveness remains controversial, with previous meta-analyses confounded by the inclusion of retrospective cohort studies. No systematic synthesis has exclusively evaluated prospective randomized controlled trials with formal GRADE certainty assessments. To compare the perioperative, postoperative, and economic outcomes of da Vinci robotic versus laparoscopic adrenalectomy for adrenal neoplasms through GRADE-assessed meta-analysis restricted to prospective randomized trials. This systematic review and meta-analysis was registered in PROSPERO (ID: CRD420251276037) on December 27, 2025. A systematic literature search (inception to December 2025) was performed to identify prospective randomized trials comparing robotic and laparoscopic adrenalectomy. Two independent reviewers performed the screening, extraction, and Cochrane RoB 2. Random-effects meta-analyses were used to pool operative time, blood loss, conversion, length of stay, complications, and cost. Heterogeneity was assessed using I² with pre-specified sensitivity and subgroup analyses. The GRADE system was used to evaluate the certainty of the evidence. Three randomized trials (n = 214 patients) met the inclusion criteria. Robotic adrenalectomy showed no statistically significant difference compared with laparoscopy in terms of operative time (MD 14.88 min, 95% CI - 25.18 to 54.95; P = 0.47; I²=94%; very low certainty), hospital stay (MD 0.04 days, 95% CI - 0.29 to 0.38; P = 0.80; I²=0%; low certainty), conversion rates (RR 0.72, 95% CI 0.05 to 10.58; P = 0.81; I²=60%; very low certainty), postoperative complications (RR 1.52, 95% CI 0.69 to 3.36; P = 0.30; I²=0%; low certainty), or total costs (MD $2444.02, 95% CI -$906.62 to 5794.66; P = 0.15; I²=99%; very low certainty). Estimated blood loss showed a statistically significant reduction with robotics (MD - 4.86 mL, 95% CI - 9.55 to - 0.18; P = 0.04; I²=0%; low certainty), but this 5 mL difference had no clinical relevance in procedures with typical blood loss under 50 mL. Sensitivity analysis identified Morino et al.2004 as the primary driver of heterogeneity in operative duration and conversion rates. Robotic adrenalectomy achieves perioperative and postoperative outcomes equivalent to laparoscopy for adrenal neoplasms, with low-to-very-low certainty evidence showing no meaningful differences in operative efficiency, recovery, complications or costs. Platform selection should prioritize surgeon expertise and case complexity rather than the expectation of universal benefit. Adequately powered trials in high-complexity populations are needed to identify the contexts in which robotic assistance provides measurable clinical value.

使用达芬奇平台的机器人辅助肾上腺切除术在理论上比传统腹腔镜手术有优势,包括增强的可视化、优越的器械关节和改进的人体工程学。然而,它们的比较有效性仍然存在争议,先前的荟萃分析因纳入回顾性队列研究而混淆。没有系统的综合研究专门评价具有正式GRADE确定性评价的前瞻性随机对照试验。通过对前瞻性随机试验进行grade评估的荟萃分析,比较达芬奇机器人与腹腔镜肾上腺切除术治疗肾上腺肿瘤的围手术期、术后和经济效果。该系统评价和荟萃分析于2025年12月27日在PROSPERO (ID: CRD420251276037)注册。通过系统的文献检索(从开始到2025年12月)来确定比较机器人和腹腔镜肾上腺切除术的前瞻性随机试验。两名独立审稿人进行了筛选、提取和Cochrane RoB 2。随机效应荟萃分析用于汇总手术时间、出血量、转归、住院时间、并发症和费用。异质性评估采用I²预先指定的敏感性和亚组分析。GRADE系统用于评价证据的确定性。三个随机试验(n = 214例患者)符合纳入标准。与腹腔镜相比,机器人肾上腺切除术在手术时间(MD 14.88 min, 95% CI - 25.18 ~ 54.95; P = 0.47; I²=94%;极低确定性)、住院时间(MD 0.04天,95% CI - 0.29 ~ 0.38; P = 0.80; I²=0%;低确定性)、转归率(RR 0.72, 95% CI 0.05 ~ 10.58; P = 0.81; I²=60%;极低确定性)、术后并发症(RR 1.52, 95% CI 0.69 ~ 3.36; P = 0.30; I²=0%;低确定性)或总成本(MD为2444.02美元,95% CI为906.62至5794.66;P = 0.15; I²=99%;极低确定性)。估计失血量在统计学上显著减少(MD - 4.86 mL, 95% CI - 9.55至- 0.18;P = 0.04; I²=0%;低确定性),但这5 mL的差异在典型失血量低于50 mL的手术中没有临床相关性。敏感性分析确定Morino et al.2004是手术时间和转换率异质性的主要驱动因素。机器人肾上腺切除术的围手术期和术后效果与腹腔镜手术治疗肾上腺肿瘤相当,低至极低的确定性证据表明,手术效率、恢复、并发症或成本没有显著差异。平台的选择应优先考虑外科医生的专业知识和病例的复杂性,而不是期望普遍受益。需要在高度复杂的人群中进行足够有力的试验,以确定机器人辅助提供可衡量的临床价值的背景。
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引用次数: 0
Economic assessment of next-generation robotic surgical systems compared with the multiport da Vinci platform: a comprehensive review. 与多端口达芬奇平台相比,下一代机器人手术系统的经济评估:全面回顾。
IF 3 3区 医学 Q2 SURGERY Pub Date : 2026-01-28 DOI: 10.1007/s11701-025-03114-6
Maria Chiara Sighinolfi, Giuseppe Pallotta, Francesco Rossi, Giovanni Filomena, Simone Assumma, Filippo Gavi, Enrico Panio, Marco Montesi, Nicoletta Testori, Simona Presutti, Angelo Totaro, Filippo Turri, Mauro Ragonese, Pierluigi Russo, Riccardo Bientinesi, Giuseppe Palermo, Carlo Gandi, Nazario Foschi, Ela Patel, Bernardo Rocco

The global landscape of robotic-assisted surgery is undergoing rapid transformation as new platforms emerge to challenge the long-standing dominance of the da Vinci (DV) system. Although DV remains the most widely adopted robotic platform worldwide, its high acquisition and maintenance costs have limited diffusion, particularly in resource-constrained regions. Next-generation systems-including Hugo RAS, Versius, Senhance, Hinotori, KangDuo, Sentire, and Micro Hand S-aim to expand access through reduced capital expenditure, reusable instrumentation, alternative cost structures, and modular architectures. This narrative review synthesizes available studies comparing the economic performance of these new technologies - including da Vinci Single-Port - with the DV multiport. A systematic search across PubMed, Scopus, and Cochrane Library identified 14 comparative cost studies through October 2025. Radical prostatectomy was the most frequently evaluated procedure, with additional analyses focused on colorectal surgery, hysterectomy, sacrocolpopexy, total mesorectal excision, and pyeloplasty. Overall, emerging platforms demonstrate heterogeneous but promising economic profiles. Hugo RAS and KangDuo showed lower overall procedural expenses in some series, although early inefficiencies may increase initial non-surgical operative time until team proficiency improved. The da Vinci Single Port platform demonstrated possible cost increases relative to the multiport system, largely influenced by institutional discharge pathways and disposable pricing. Economic outcomes varied markedly across institutions, driven by local procurement policies, instrument pricing, operative workflows, and reimbursement models. Current evidence suggests that new robotic platforms can reduce specific cost components without compromising clinical outcomes, yet generalizability remains limited. Standardized, prospective cost evaluations incorporating acquisition models, non-surgical time, learning curves, and long-term outcomes are essential to determine true value across healthcare settings.

随着新平台的出现,机器人辅助手术的全球格局正在经历快速转变,挑战达芬奇(DV)系统的长期统治地位。虽然DV仍然是世界上最广泛采用的机器人平台,但其高昂的获取和维护成本限制了推广,特别是在资源有限的地区。包括Hugo RAS、Versius、senance、Hinotori、KangDuo、sente和Micro Hand s在内的下一代系统旨在通过减少资本支出、可重用仪器、替代成本结构和模块化架构来扩大使用范围。这篇叙述性综述综合了现有的研究,比较了这些新技术的经济性能,包括达芬奇单端口与DV多端口。通过对PubMed、Scopus和Cochrane图书馆的系统搜索,到2025年10月确定了14项比较成本研究。根治性前列腺切除术是最常见的评估方法,其他分析集中在结直肠手术、子宫切除术、骶结肠固定术、全肠系膜切除术和肾盂成形术。总的来说,新兴平台呈现出不同的但有前景的经济概况。Hugo RAS和KangDuo在某些系列中显示出较低的总体手术费用,尽管早期效率低下可能会增加初始非手术手术时间,直到团队熟练程度提高。达芬奇单端口平台表明,相对于多端口系统,成本可能会增加,这在很大程度上受到机构排放途径和一次性定价的影响。受当地采购政策、仪器定价、操作流程和报销模式的影响,不同机构的经济结果差异很大。目前的证据表明,新的机器人平台可以在不影响临床结果的情况下降低特定的成本组成部分,但推广仍然有限。标准化的前瞻性成本评估,包括获取模型、非手术时间、学习曲线和长期结果,对于确定整个医疗保健环境的真正价值至关重要。
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引用次数: 0
Adoption and expansion of robotic surgery across General Surgery in the United Kingdom: a 10-year procedure-specific analysis (2015-2024). 机器人手术在英国普通外科的采用和扩展:一项10年手术特定分析(2015-2024)。
IF 3 3区 医学 Q2 SURGERY Pub Date : 2026-01-28 DOI: 10.1007/s11701-025-03073-y
Neil Donald, Joseph Sebastian, Giuseppe Preziosi
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引用次数: 0
A standardized linear-stapled side-to-side anastomotic technique in robot-assisted Ivor Lewis esophagectomy: a retrospective analysis of 350 consecutive cases from a prospective registry. 机器人辅助Ivor Lewis食管切除术的标准化线性吻合器侧对侧吻合技术:对前瞻性登记的350例连续病例的回顾性分析。
IF 3 3区 医学 Q2 SURGERY Pub Date : 2026-01-24 DOI: 10.1007/s11701-025-03132-4
A Zeyara, E A Kouwenhoven, H T J Mantel, M J van Det

Early experiences with robotic-assisted esophagectomy showed disappointing anastomotic outcomes when techniques were directly translated from open or thoracoscopic surgery. Among intrathoracic anastomotic options in robot-assisted Ivor Lewis esophagectomy (RAMIE-IL), emerging data suggest lower complication rates with the linear stapled side-to-side technique. This method was adopted at our institution in 2018. Here, we present our outcomes and describe our standardized linear-stapled side-to-side anastomosis for RAMIE-IL. The primary objective of this study was to detail the surgical technique and evaluate postoperative outcomes of a linear-stapled side-to-side anastomosis in RAMIE-IL. This retrospective cohort study used prospectively collected registry data of all consecutive patients undergoing RAMIE-IL with an intrathoracic linear-stapled side-to-side anastomosis at ZGT Almelo, The Netherlands. All patients from inception (July 1st, 2018) until November 15th, 2025, were included. Data were obtained from the Dutch Upper GI Cancer Audit (DUCA) registry. 350 consecutive patients were included. Mean age was 66 years, 70% were male and 44% had an ASA-class of 3 or more. Length of ICU stay was median 1 days. Length of hospital stay was median 7 days. Overall anastomotic leak rate was 4%. Overall rate of all Clavien-Dindo ≥ 3 complications was 14%. Readmission rate within 30 days was 12.5%. 30-day mortality rate was 1.7%. The presented linear-stapled side-to-side anastomotic technique is feasible and associated with a low rate of anastomotic complications in the studied cohort.

早期机器人辅助食管切除术的经验表明,当技术直接从开放或胸腔镜手术转化时,吻合结果令人失望。在机器人辅助Ivor Lewis食管切除术(RAMIE-IL)的胸内吻合选择中,新出现的数据表明线性侧对侧吻合术的并发症发生率较低。该方法于2018年在我院采用。在这里,我们介绍了我们的结果,并描述了我们对RAMIE-IL的标准化线性吻合器侧对侧吻合。本研究的主要目的是详细介绍RAMIE-IL的手术技术和评估线性订钉侧对侧吻合的术后结果。这项回顾性队列研究前瞻性地收集了所有在荷兰ZGT Almelo接受RAMIE-IL胸内线钉侧对侧吻合的连续患者的注册资料。纳入研究开始(2018年7月1日)至2025年11月15日的所有患者。数据来自荷兰上消化道癌症审计(DUCA)登记处。纳入了350例连续患者。平均年龄66岁,70%为男性,44%为asa 3级及以上。ICU住院时间中位数为1天。住院时间中位数为7天。吻合口漏总发生率为4%。Clavien-Dindo≥3并发症的总发生率为14%。30天内再入院率为12.5%。30天死亡率为1.7%。所提出的线性吻合器侧对侧吻合技术是可行的,并且在研究队列中吻合并发症发生率低。
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引用次数: 0
Early outcomes of subcostal four-arm robotic pulmonary resection and mediastinal lymph node dissection for non-small cell lung cancer. 肋下四臂机械肺切除和纵隔淋巴结清扫治疗非小细胞肺癌的早期疗效。
IF 3 3区 医学 Q2 SURGERY Pub Date : 2026-01-23 DOI: 10.1007/s11701-026-03164-4
Dong Kyu Yoon, Woohyun Jung, Jae Hyun Jeon, Sukki Cho, Kwhanmien Kim

We report the early outcomes of subcostal robot-assisted thoracic surgery (subRATS) for non-small cell lung cancer (NSCLC). We conducted a prospective, single-arm cohort study at Seoul National University Bundang Hospital beginning in June 2022 to evaluate the feasibility of subRATS for pulmonary resection in NSCLC. This interim analysis assessed outcomes in consecutive patients from June 2022 to June 2025. The operative times for a subgroup of patients who underwent lobectomy were also analyzed using cumulative sum (CUSUM) analysis to assess procedural reproducibility. A total of 102 patients were included, with a mean age of 63.3 years. Lobectomy was performed in 79 patients and segmentectomy in 21 patients. Systematic mediastinal lymph node (LN) dissection was completed in 47 patients. Nodal upstaging occurred in 11 cases, with eight patients upstaged to N2 disease. The mean console time was 106.6 min, and the average postoperative hospital stay was 3.6 days. Postoperative complications of Clavien-Dindo grade III or higher were observed in 4 patients: one 30-day mortality due to postoperative myocardial infarction, one conversion to thoracotomy due to bleeding, and two cases of transient recurrent laryngeal nerve injury. No postoperative diaphragmatic abnormalities were observed. CUSUM analysis identified the 31st case as the turning point on the learning curve, after which marked reductions in operative time, estimated blood loss, and length of hospital stay were achieved. SubRATS is feasible and reproducible for pulmonary resection and mediastinal LN dissection in patients with NSCLC, with the added advantage of sparing the intercostal nerve.

我们报告了肋下机器人辅助胸外科手术(subRATS)治疗非小细胞肺癌(NSCLC)的早期结果。我们从2022年6月开始在首尔国立大学盆唐医院进行了一项前瞻性单臂队列研究,以评估subRATS用于非小细胞肺癌肺切除术的可行性。该中期分析评估了2022年6月至2025年6月连续患者的结局。一组接受肺叶切除术的患者的手术时间也使用累积和(CUSUM)分析来评估手术的可重复性。共纳入102例患者,平均年龄63.3岁。79例患者行肺叶切除术,21例患者行节段切除术。47例患者完成了系统纵隔淋巴结清扫。11例发生淋巴结抢先期,其中8例抢先期为N2病。平均安慰时间106.6 min,术后平均住院时间3.6 d。Clavien-Dindo III级及以上术后并发症4例:1例因术后心肌梗死30天死亡,1例因出血转开胸,2例一过性喉返神经损伤。术后未见膈异常。CUSUM分析将第31例确定为学习曲线的转折点,此后手术时间、估计失血量和住院时间均显著减少。对于非小细胞肺癌患者的肺切除和纵隔LN清扫,SubRATS是可行和可重复性的,并且具有保留肋间神经的额外优势。
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Journal of Robotic Surgery
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