Introduction: Constipation is recognized as a common gastrointestinal problem that many sick and healthy individuals suffer from. Laxative therapy is a reliable way to treat constipation. Several medicinal plants exert laxative potential. Hence, we decided to identify medicinal plants with laxative properties in Arasbaran Forests, East Azerbaijan Province, Northwest Iran. Methods: This ethnobotanical study was conducted in Arasbaran Forests, East Azerbaijan Province, and Northwest Iran from October 2022 to December 2022. Questionnaires were distributed among 20 traditional medicine doctors and finally, traditional information on the therapeutic effect of medicinal plants was collected through interviews. Demographic information from indigenous people who have traditional botanical knowledge was also collected. Eventually, the data were analyzed. Results: Our work revealed that thirteen medicinal herbs from 11 herbal families have potent laxative effects. The Berberidaceae, Equisetaceae, Caprifoliaceae, Celasteraceae, Asteraceae, Cucurbitaceae, Euphorbiaceae, Grossulariaceae, Polygonacea, Polypodiaceae, and Rosaceae families had laxative effects. Fruit, leaves, aerial parts, bark, root, and rhizome were the most effective parts, respectively. These medicinal plants were administrated in decoction and fresh form. Conclusion: The findings show the traditional laxative effects of medicinal plants against constipation in this region, which have traditional uses. Therefore, identifying the phytochemical constituents of these plants and understanding the mechanism of their laxative effect can be helpful.
{"title":"Ethnobotanical Study of Effective Medicinal Plants as Laxative (Anti-constipation): A Case Study in Arasbaran Forests, Northwest Iran","authors":"Ehsan Bahmani, Fariba Bahmani, Saber Abbaszadeh","doi":"10.34172/jbp.2023.12","DOIUrl":"https://doi.org/10.34172/jbp.2023.12","url":null,"abstract":"Introduction: Constipation is recognized as a common gastrointestinal problem that many sick and healthy individuals suffer from. Laxative therapy is a reliable way to treat constipation. Several medicinal plants exert laxative potential. Hence, we decided to identify medicinal plants with laxative properties in Arasbaran Forests, East Azerbaijan Province, Northwest Iran. Methods: This ethnobotanical study was conducted in Arasbaran Forests, East Azerbaijan Province, and Northwest Iran from October 2022 to December 2022. Questionnaires were distributed among 20 traditional medicine doctors and finally, traditional information on the therapeutic effect of medicinal plants was collected through interviews. Demographic information from indigenous people who have traditional botanical knowledge was also collected. Eventually, the data were analyzed. Results: Our work revealed that thirteen medicinal herbs from 11 herbal families have potent laxative effects. The Berberidaceae, Equisetaceae, Caprifoliaceae, Celasteraceae, Asteraceae, Cucurbitaceae, Euphorbiaceae, Grossulariaceae, Polygonacea, Polypodiaceae, and Rosaceae families had laxative effects. Fruit, leaves, aerial parts, bark, root, and rhizome were the most effective parts, respectively. These medicinal plants were administrated in decoction and fresh form. Conclusion: The findings show the traditional laxative effects of medicinal plants against constipation in this region, which have traditional uses. Therefore, identifying the phytochemical constituents of these plants and understanding the mechanism of their laxative effect can be helpful.","PeriodicalId":476420,"journal":{"name":"Journal of Biochemicals and Phytomedicine","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136365960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Obesity is one of the problems of current century, which is the cause of complex disorders of organs and systems of the human body, up to the development of lethal outcomes. The modern market of pharmaceutical medicine preparations for treatment and prevention is quite extensive. The main treatment of diseases that is proven on the basis of evidence, including for preventive purposes, is the inclusion of such drugs in fever protocols throughout the country. The purpose of this study is to examine the current market of drugs for the prevention and treatment of obesity in Ukraine.
{"title":"The Current Market of Pharmacological Drugs for the Prevention and Treatment of Obesity in Ukraine: A Review","authors":"Kateryna Ivanivna Smetanina","doi":"10.34172/jbp.2023.8","DOIUrl":"https://doi.org/10.34172/jbp.2023.8","url":null,"abstract":"Obesity is one of the problems of current century, which is the cause of complex disorders of organs and systems of the human body, up to the development of lethal outcomes. The modern market of pharmaceutical medicine preparations for treatment and prevention is quite extensive. The main treatment of diseases that is proven on the basis of evidence, including for preventive purposes, is the inclusion of such drugs in fever protocols throughout the country. The purpose of this study is to examine the current market of drugs for the prevention and treatment of obesity in Ukraine.","PeriodicalId":476420,"journal":{"name":"Journal of Biochemicals and Phytomedicine","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136365836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Fever is a common symptom in several diseases. Medicinal plants have a long history in dealing with diseases. Hence, the objective of this ethnobotanical study was to identify herbs used for the management of fever in Sojas Rud district in Khodabandeh County, Zanjan province, Northwest Iran. Methods: This ethnobotanical study was carried out in Sojas Rud district in Khodabandeh County, Zanjan province, Northwest Iran. Collection of ethnobotanical information as done through interviews and questionnaires among 22 traditional healers. Demographic information was also collected. The data were analyzed by Excel. Results: Our findings revealed that 10 medicinal herbs including Anthemis nobilis L., Centaurea depressa L., Crataegus monogyna, Descurainia Sophia L., Elaeagnus angustifolia L, Gundelia tourneforti L., Nasturtium officinalis, Orchis latifolia L., Plantago lanceolata L., and Salix spp. from 7 families had a considerable effect in the management of fever. We have also observed that the medicinal herbs in Asteraceae, Rosaceae, Brassicaceae, Elaeagnaceae, Orchidaceae, Plantaginaceae, and Saliaceae families had the effect on controlling fever. Furthermore, our results demonstrated that the flower, stem, fruit, seed, leaf, aerial parts, tuber, root, and bark of these plants were the effective parts, respectively. In addition, most forms of preparation of these plants were decoction, fresh, infusion, cooked, and syrup, respectively. Conclusion: The presented study revealed the remarkable effect of some new medicinal plants against fever. Therefore, further studies in the field of investigating the effects of medicinal plants on fever with the approach of identifying the role of the phytochemical constituents of these plants and their effective mechanisms on fever treatment can be a way forward.
{"title":"Identification of Important Herbs for Anti-fever Treatment: An Ethnobotanical Study of Sojas Rud, Northwest Iran","authors":"Mahdeyeh Ahmadi, Fateme Khajoei Nejad, Neda Dastyar","doi":"10.34172/jbp.2023.11","DOIUrl":"https://doi.org/10.34172/jbp.2023.11","url":null,"abstract":"Introduction: Fever is a common symptom in several diseases. Medicinal plants have a long history in dealing with diseases. Hence, the objective of this ethnobotanical study was to identify herbs used for the management of fever in Sojas Rud district in Khodabandeh County, Zanjan province, Northwest Iran. Methods: This ethnobotanical study was carried out in Sojas Rud district in Khodabandeh County, Zanjan province, Northwest Iran. Collection of ethnobotanical information as done through interviews and questionnaires among 22 traditional healers. Demographic information was also collected. The data were analyzed by Excel. Results: Our findings revealed that 10 medicinal herbs including Anthemis nobilis L., Centaurea depressa L., Crataegus monogyna, Descurainia Sophia L., Elaeagnus angustifolia L, Gundelia tourneforti L., Nasturtium officinalis, Orchis latifolia L., Plantago lanceolata L., and Salix spp. from 7 families had a considerable effect in the management of fever. We have also observed that the medicinal herbs in Asteraceae, Rosaceae, Brassicaceae, Elaeagnaceae, Orchidaceae, Plantaginaceae, and Saliaceae families had the effect on controlling fever. Furthermore, our results demonstrated that the flower, stem, fruit, seed, leaf, aerial parts, tuber, root, and bark of these plants were the effective parts, respectively. In addition, most forms of preparation of these plants were decoction, fresh, infusion, cooked, and syrup, respectively. Conclusion: The presented study revealed the remarkable effect of some new medicinal plants against fever. Therefore, further studies in the field of investigating the effects of medicinal plants on fever with the approach of identifying the role of the phytochemical constituents of these plants and their effective mechanisms on fever treatment can be a way forward.","PeriodicalId":476420,"journal":{"name":"Journal of Biochemicals and Phytomedicine","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136365968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Meat and meat products are very valuable and widely consumed, therefore, it is necessary to detect fraud in these products. The purpose of this review is to introduce and debate on quick and easy diagnostic methods for the identity of meat and meat products. For carrying out this review, scientific databases and search engines for finding the articles were "Google Scholar", "SID", "Scopus", "PubMed", "Science Direct", and "ISI". The search was done for articles published that included the search term containing, authentication, meat products, health, and risk assessment in their title. This study focused on published articles from 2016 to 2022. The studies indicated that classical analytical methods have replaced fast, simple, and non-invasive methods to increase productivity and profitability in the meat supply chain. Fourier transform infrared (FTIR) spectroscopy, near infrared (NIR) spectroscopy have become valuable analytical methods for structural or functional studies related to foods as a fast, non-destructive, cost-effective, and sensitive physicochemical fingerprinting method. The studies indicate that ATR-FTIR spectroscopy had better results statistically and functionally.
{"title":"Identifying the Fraud and Authenticity of Meat Products by Infrared Spectroscopy: A Systematic Review","authors":"Nabi Shariatifar, Mohadeseh Pirhadi","doi":"10.34172/jbp.2023.9","DOIUrl":"https://doi.org/10.34172/jbp.2023.9","url":null,"abstract":"Meat and meat products are very valuable and widely consumed, therefore, it is necessary to detect fraud in these products. The purpose of this review is to introduce and debate on quick and easy diagnostic methods for the identity of meat and meat products. For carrying out this review, scientific databases and search engines for finding the articles were \"Google Scholar\", \"SID\", \"Scopus\", \"PubMed\", \"Science Direct\", and \"ISI\". The search was done for articles published that included the search term containing, authentication, meat products, health, and risk assessment in their title. This study focused on published articles from 2016 to 2022. The studies indicated that classical analytical methods have replaced fast, simple, and non-invasive methods to increase productivity and profitability in the meat supply chain. Fourier transform infrared (FTIR) spectroscopy, near infrared (NIR) spectroscopy have become valuable analytical methods for structural or functional studies related to foods as a fast, non-destructive, cost-effective, and sensitive physicochemical fingerprinting method. The studies indicate that ATR-FTIR spectroscopy had better results statistically and functionally.","PeriodicalId":476420,"journal":{"name":"Journal of Biochemicals and Phytomedicine","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136365974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amir Soltanbeigi, Mohadeseh Pirhadi, Sedef Özliman
Introduction: There are various drugs and methods to deal with anorexia, but both have adverse effects and limited effectiveness. Dissatisfaction of people with expensive chemical drugs that have many side effects as well as the desire to get fit through natural methods are important reasons for people to use herbal drugs. Considering that many plants used by people are used in the treatment of anorexia, this study aims to identify and report the plants that are used in the treatment of anorexia/hypophagia in the ethnobotanical knowledge of Musian city in order to facilitate access to them. Methods: This ethnobotanical study was conducted from May 2022 to January 2023 through face-to-face interviews and using a questionnaire among 28 traditional healers in Musian (West Iran). These questionnaires included demographic and specialized information on the medicinal plants of the 28 people who participated in this study. The results obtained from the questionnaires were directly transferred to the relevant tables and recorded. Finally, the data were analyzed by Excel. Results: The results of the study showed that in Musian 12 species of medicinal plants including Amygdalus communis L., Centaurea solstitialis L., Ficus carica, Malva neglecta Wallr, Menta longifolia (L.) Hudson, Rhus coriaria L, Tymbra spicata, Medicago sativa, Linum usitatissimum, Achillea wilhelmsii C. Kock, Alhagi persarum, and Alyssum campestre are in the ethnobotanical knowledge of this region as herbal medicine for anorexia (appetizer). Asteraceae, Laminaceae, and Fabaceae with two plant species are the most plant families that are used as appetizers in the region. The aerial organs were identified as 46% of the most used plant organs. Conclusion: The presence of rich plant flora and medicinal plant species in Musian city shows that this region is rich in medicinal plants and this issue can provide a suitable ground for better use of medicinal plants of this city to produce appetizing herbal products.
{"title":"Ethno-Botanical Study of Appetizing Medicinal Plants Used in Musian City, West of Iran","authors":"Amir Soltanbeigi, Mohadeseh Pirhadi, Sedef Özliman","doi":"10.34172/jbp.2023.14","DOIUrl":"https://doi.org/10.34172/jbp.2023.14","url":null,"abstract":"Introduction: There are various drugs and methods to deal with anorexia, but both have adverse effects and limited effectiveness. Dissatisfaction of people with expensive chemical drugs that have many side effects as well as the desire to get fit through natural methods are important reasons for people to use herbal drugs. Considering that many plants used by people are used in the treatment of anorexia, this study aims to identify and report the plants that are used in the treatment of anorexia/hypophagia in the ethnobotanical knowledge of Musian city in order to facilitate access to them. Methods: This ethnobotanical study was conducted from May 2022 to January 2023 through face-to-face interviews and using a questionnaire among 28 traditional healers in Musian (West Iran). These questionnaires included demographic and specialized information on the medicinal plants of the 28 people who participated in this study. The results obtained from the questionnaires were directly transferred to the relevant tables and recorded. Finally, the data were analyzed by Excel. Results: The results of the study showed that in Musian 12 species of medicinal plants including Amygdalus communis L., Centaurea solstitialis L., Ficus carica, Malva neglecta Wallr, Menta longifolia (L.) Hudson, Rhus coriaria L, Tymbra spicata, Medicago sativa, Linum usitatissimum, Achillea wilhelmsii C. Kock, Alhagi persarum, and Alyssum campestre are in the ethnobotanical knowledge of this region as herbal medicine for anorexia (appetizer). Asteraceae, Laminaceae, and Fabaceae with two plant species are the most plant families that are used as appetizers in the region. The aerial organs were identified as 46% of the most used plant organs. Conclusion: The presence of rich plant flora and medicinal plant species in Musian city shows that this region is rich in medicinal plants and this issue can provide a suitable ground for better use of medicinal plants of this city to produce appetizing herbal products.","PeriodicalId":476420,"journal":{"name":"Journal of Biochemicals and Phytomedicine","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136365966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: The treatment of most diseases in dentistry is related to the local application of antiseptic drugs that regulate the microbiocenosis in the oral cavity. The study of pharmacodynamic and kinetic parameters of the release of active pharmaceutical ingredients (APIs) from the dosage form (DF) is an important task. In this study, we tried to evaluate the release of APIs from developed dental medicinal films (DMF) produced on a polymeric basis. Methods: To confirm the antimicrobial activity of the three developed DMF with amizon, decamethoxine and chlorhexidine digluconate, a statistical analysis and mathematical processing of the research results were carried out. Results: Statistical processing made it possible to organize the results of our earlier studies, in which the concentrations of three APIs (amizon, decamethoxine, and chlorhexidine digluconate) were determined during their diffusion from the polymer base of the DMF to the aqueous dispersion medium (0.9% sodium chloride solution). Due to performed statistical calculations, regarding the reliability of APIs release, it was determined that the time duration of complete release of the three active substances from the polymer base was different, which will ultimately affect the duration of the pharmacological effect of the APIs in the patient's body. Conclusion: In the manufacture of DMF on a polymeric base of hydrophilic type, it is necessary to take into account the release time of each API, according to the composition of the polymeric coatings.
{"title":"Research Design of the Release of Amizon, Decametoxine, and Chlorhexidine from the Composition of Dental Medicinal Films","authors":"Ihor Hrynovets, Volodymyr Hrynovets, Roman Lysiuk","doi":"10.34172/jbp.2023.13","DOIUrl":"https://doi.org/10.34172/jbp.2023.13","url":null,"abstract":"Introduction: The treatment of most diseases in dentistry is related to the local application of antiseptic drugs that regulate the microbiocenosis in the oral cavity. The study of pharmacodynamic and kinetic parameters of the release of active pharmaceutical ingredients (APIs) from the dosage form (DF) is an important task. In this study, we tried to evaluate the release of APIs from developed dental medicinal films (DMF) produced on a polymeric basis. Methods: To confirm the antimicrobial activity of the three developed DMF with amizon, decamethoxine and chlorhexidine digluconate, a statistical analysis and mathematical processing of the research results were carried out. Results: Statistical processing made it possible to organize the results of our earlier studies, in which the concentrations of three APIs (amizon, decamethoxine, and chlorhexidine digluconate) were determined during their diffusion from the polymer base of the DMF to the aqueous dispersion medium (0.9% sodium chloride solution). Due to performed statistical calculations, regarding the reliability of APIs release, it was determined that the time duration of complete release of the three active substances from the polymer base was different, which will ultimately affect the duration of the pharmacological effect of the APIs in the patient's body. Conclusion: In the manufacture of DMF on a polymeric base of hydrophilic type, it is necessary to take into account the release time of each API, according to the composition of the polymeric coatings.","PeriodicalId":476420,"journal":{"name":"Journal of Biochemicals and Phytomedicine","volume":"217 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136365973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Medicinal plants have shown special application in the pharmaceutical and food industries. Chemical analysis and determination of medicinal compounds of medicinal plants attract great attention throughout the world. The present study was designed to evaluate the phytochemical properties and antioxidant activity of methanol extract of three species of aromatic plants by FTIR method. Methods: Three species of aromatic plants including Konar (Ziziphus spina-christi), rosemary (Salvia rosmarinus), and Marzeh khuzestani (Satureja khuzistanica) were prepared and studied from the cities of Dehlran and Ilam locating in the west of Iran. These medicinal plants were dried and then powdered. The active groups of the medicinal plants were identified by the FT-IR method. Total antioxidant capacity was measured based on divalent iron reducing ability (FRAP) and by a single electron transfer mechanism. Results: The FT-IR results displayed that Z. spina-christi surrounds 11 functional groups, rosemary has 13 functional groups, and Khuzestani pepper contains 12 functional groups. The antioxidant potential of the methanolic extract of Z. spina-christi was 7 mmol Fe2+/L, rosemary was 1.93 mmol Fe2+/L, and Marzeh khuzestani was 12.99 mmol Fe2+/L. Conclusion: Ziziphus spina-christi, Salvia rosmarinus, and Satureja Khuzestani have strong antioxidant properties due to their chemical compounds and can be used for medicinal purposes.
{"title":"Evaluation of Phytochemical Properties and Antioxidant Activity of Methanol Extract of Ziziphus Spina-Christi, Satureja Khuzistanica, and Salvia Rosmarinus Using FT-IR Method","authors":"Fatehalrahman Faris Magbool Alrekaby, Ahed J Alkhatib, Hassan Abubakar, Samira Shokri","doi":"10.34172/jbp.2023.10.","DOIUrl":"https://doi.org/10.34172/jbp.2023.10.","url":null,"abstract":"Introduction: Medicinal plants have shown special application in the pharmaceutical and food industries. Chemical analysis and determination of medicinal compounds of medicinal plants attract great attention throughout the world. The present study was designed to evaluate the phytochemical properties and antioxidant activity of methanol extract of three species of aromatic plants by FTIR method. Methods: Three species of aromatic plants including Konar (Ziziphus spina-christi), rosemary (Salvia rosmarinus), and Marzeh khuzestani (Satureja khuzistanica) were prepared and studied from the cities of Dehlran and Ilam locating in the west of Iran. These medicinal plants were dried and then powdered. The active groups of the medicinal plants were identified by the FT-IR method. Total antioxidant capacity was measured based on divalent iron reducing ability (FRAP) and by a single electron transfer mechanism. Results: The FT-IR results displayed that Z. spina-christi surrounds 11 functional groups, rosemary has 13 functional groups, and Khuzestani pepper contains 12 functional groups. The antioxidant potential of the methanolic extract of Z. spina-christi was 7 mmol Fe2+/L, rosemary was 1.93 mmol Fe2+/L, and Marzeh khuzestani was 12.99 mmol Fe2+/L. Conclusion: Ziziphus spina-christi, Salvia rosmarinus, and Satureja Khuzestani have strong antioxidant properties due to their chemical compounds and can be used for medicinal purposes.","PeriodicalId":476420,"journal":{"name":"Journal of Biochemicals and Phytomedicine","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136365837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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