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Intraventricular Neurocystecercosis with Psychiatry Manifestations 伴有精神病学表现的脑室内神经囊虫病
Pub Date : 2023-09-12 DOI: 10.58739/jcbs/v13i2.23.26
A Anitha, P Kruthi, K Prabhakar
Neurocysticercosis (NCC)is one of the common parasitic infection of the central nervous system, caused by tenia solium. We present here a case of 19-year-old female presented with partial hanging, on CT brain incidentally found to have asymmetric ectasia of right lateral ventricle, for which MRI was done revealed - intraventricular neurocysticercosis causing obstructive hydrocephalus. Extra parenchymal neurocysticercosis can occur in ventricles, sub arachnoid space, spine and eyes. A recent study reported an overall frequency of subarachnoid cysts in 2%, ventricular cysts in 6%, and hydrocephalus in 16% of NCC cases. It may be associated with any neurological sign and symptom. Focal neurological deficits have been recognized in one-third of symptomatic patients. Motor deficits, involuntary movements, Parkinsonism, language disturbances, sensory deficits may occur in some patients. Psychiatric disorders may mark the evolution of hydrocephalus, As in our case, patient with unilateral hydrocephalus presented with alleged history of hanging , it is important to rule out organic brain diseases in all cases with psychiatry manifestations. Keywords: Neurocysticercosis, Hydrocephalus, Psychiatry disorder
神经囊虫病(NCC)是一种常见的中枢神经系统寄生虫感染,由猪头绦虫引起。我们在此报告一位19岁女性患者,在CT上偶然发现右侧侧脑室不对称扩张,MRI显示-脑室内神经囊虫病引起梗阻性脑积水。脑实质外神经囊虫病可发生在脑室、蛛网膜下腔、脊柱和眼睛。最近的一项研究报告了NCC病例中蛛网膜下腔囊肿的总发生率为2%,脑室囊肿为6%,脑积水为16%。它可能与任何神经体征和症状有关。局灶性神经功能障碍在三分之一的有症状的患者中得到确认。一些患者可能出现运动缺陷、不自主运动、帕金森症、语言障碍、感觉缺陷。精神障碍可能标志着脑积水的发展,如本病例,单侧脑积水患者有所谓的上吊史,在所有有精神病学表现的病例中,排除器质性脑疾病是很重要的。关键词:脑囊虫病,脑积水,精神障碍
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引用次数: 0
Mystery of the Treatment of Syphilis 梅毒治疗的奥秘
Pub Date : 2023-09-12 DOI: 10.58739/jcbs/v13i2.22.117
T S Rajashekar, Kumar K Suresh, E Meghana, T R Pavithra, Chowdary Y Deepthi, K Hanumanthayya
Syphilis is the commonest sexually transmitted disease (STD) affecting humans globally. On 12.10.1492, Christopher Columbus with his crew landed in Haiti (America) and returned to Spain (Europe) on 15th March 1493. Historians believe that, he and his crew members spread the disease syphilis in Europe, which he and his crew members had contracted in Haiti. The migration of people due to war (soldiers and mercenaries), merchants and slave trade contributed to the rapid spread of the disease and it became a pandemic. Initially, syphilis was highly contagious and virulent, affecting millions of people with very high mortality. Hence, the physicians of that time left no stone unturned for finding a cure. They tried mostly ineffective and harmful methods to treat syphilis. The drugs proved to be more harmful than curative. The fatality due to drugs itself was very significant. Alexander Fleming, a Scottish physician discovered penicillin in 1928 as a crude extract from Penicillium rubens. Eagle H and his coworkers in 1940, found that, penicillin at a relatively low dosage used over a prolonged period of four weeks cured syphilis. The discovery of penicillin enabled to transform a disease with high mortality to a manageable disease. Keywords: Syphilis, Treponema pallidum, Infectious disease
梅毒是全球范围内影响人类的最常见的性传播疾病。1492年10月12日,克里斯托弗·哥伦布和他的船员在海地(美洲)登陆,并于1493年3月15日返回西班牙(欧洲)。历史学家认为,他和他的船员将梅毒传播到欧洲,他和他的船员在海地感染了梅毒。战争造成的人口迁移(士兵和雇佣军)、商人和奴隶贸易促成了这种疾病的迅速传播,并成为一种流行病。最初,梅毒具有高度传染性和毒性,影响了数百万人,死亡率非常高。因此,当时的医生们千方百计地寻找治疗方法。他们尝试了许多无效和有害的方法来治疗梅毒。事实证明,这些药物弊大于利。药物本身造成的死亡率非常高。1928年,苏格兰医生亚历山大·弗莱明(Alexander Fleming)发现盘尼西林,当时盘尼西林是从鲁本青霉菌(Penicillium rubens)中提取的粗提取物。Eagle H和他的同事在1940年发现,青霉素在相对较低的剂量下长时间使用四周,可以治愈梅毒。青霉素的发现使一种高死亡率的疾病变成了一种可控制的疾病。关键词:梅毒,梅毒螺旋体,传染病
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引用次数: 0
Social Phobia and Procrastination as the Predictors of Perceived Stress among the School Children of Kolar Post COVID 19 Pandemic - A Cross-sectional S tudy 社交恐惧症和拖延症是Kolar新冠疫情后学龄儿童感知压力的预测因素——一项横断面S研究
Pub Date : 2023-09-12 DOI: 10.58739/jcbs/v13i2.23.16
S Anandu, Kamath B T Prasanna, T S Pradeep
The WHO defines a pandemic as spread of certain disease worldwide or across international borders, influencing many people. COVID-19 is recently found infectious coronavirus that is transmitted from person to person via droplets. Multiple studies indicating an increase in schoolchildren's procrastination can be attributable to pandemic's increased uncertainty level. To find out whether Social Phobia and Procrastination can be predictors of Perceived Stress among school children of Kolar post-COVID-19 pandemic. Data collection was from the high school children of selected schools in Kolar Taluk. Data collection was conducted using a pretested semi-structured questionnaire. “Simple random sampling” was done to select the participant schools. 2 Schools each were selected in the rural and urban areas. The design of the research was Cross-sectional and was done among students of co-education high schools in Kolar taluk. All the students in the selected schools belonging to 8th, 9th, and 10th classes were involved. The analysis tools used are the PSS-10 scale for perceived stress, Social Phobia Scale (SPS) for social phobia, and The Lay’s Procrastination Scale for measuring procrastination. The study duration was from 30th November 2022 to 31st December 2022. Assuming the stress prevalence in school children to be 50% considered as prevalence (p), “error of 5% with a 95% confidence interval, the sample size” determined was 400 [estimated by Open Epi version 3.01]. Simple Random sampling was used. All data will be put into a Microsoft Excel sheet and analyzed with SPSS v 22. (IBM Corp). The perceived stress scores are positively associated with social phobia scores and procrastination scores and this relationship was observed to be statistically significant. Both social phobia and procrastination were able to predict 89.7% of changes in the perceived stress levels among the participants. Social phobia and procrastination are the predictors of perceived stress and any intervention for stress should also consider these factors into consideration. Keywords: Perceived stress, Social Phobia, Procrastination, adolescents
世界卫生组织将大流行定义为某种疾病在全球或跨国界传播,影响许多人。COVID-19是最近发现的传染性冠状病毒,通过飞沫在人与人之间传播。多项研究表明,学童拖延症的增加可归因于大流行的不确定性水平的增加。探讨社交恐惧症和拖延症是否可以预测Kolar学龄儿童的感知压力。数据收集来自Kolar Taluk选定学校的高中生。数据收集采用预先测试的半结构化问卷进行。采用“简单随机抽样”方式选择参与学校。各有2所学校分别来自农村和城市地区。研究的设计是横断面的,是在Kolar taluk男女同校高中的学生中进行的。入选学校8、9、10班的所有学生都参与其中。使用的分析工具是用于感知压力的PSS-10量表,用于社交恐惧症的社交恐惧症量表(SPS)和用于测量拖延症的Lay 's拖延量表。研究时间为2022年11月30日至2022年12月31日。假设学龄儿童的压力患病率为50% (p),“误差为5%,置信区间为95%,”确定的样本量为400[使用Open Epi 3.01版估算]。采用简单随机抽样。所有的数据将被放入一个微软Excel表格,并与SPSS v 22分析。(IBM . n:行情))。感知压力得分与社交恐惧症得分和拖延症得分呈正相关,且这种关系具有统计学意义。社交恐惧症和拖延症都能预测参与者感知压力水平变化的89.7%。社交恐惧症和拖延症是感知压力的预测因素,任何对压力的干预都应该考虑到这些因素。关键词:感知压力,社交恐惧症,拖延症,青少年
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引用次数: 0
Assessment of Nutrition and Immunization Status of Children Attending to Anganwadis at Field Practice Area of a Rural Medical College, Karnataka 卡纳塔克邦一所农村医学院实地实习区Anganwadis儿童营养和免疫状况评估
Pub Date : 2023-09-12 DOI: 10.58739/jcbs/v13i2.23.12
S V Abhishek, B N Sunil
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引用次数: 0
Perceived Stress Levels and its Associated Factors Among Urban Population of Gandhinagar: A Community-Based Cross-Sectional Study 甘地那格尔城市人口感知压力水平及其相关因素:一项基于社区的横断面研究
Pub Date : 2023-09-12 DOI: 10.58739/jcbs/v13i2.23.17
S Anandu, Wasim Anjum
Growing stress in the developing world is a sign of unresolved physical and emotional tensions. Chronic stress has a detrimental effect on one's health and well-being. The data regarding the levels of perceived stress and its related factors among general population of India is sparse. To assess the perceived stress levels and their related factors among the urban population of Gandhinagar. Data collection was from the residents of Urban field practice area of Gandhinagar, Kolar. A pretested semi-structured questionnaire has been used for the data collection. The houses were chosen using systematic random selection. Study design was a community-based Cross-sectional study. PSS-10 scale was applied to estimate the perceived stress. The research was conducted between October 2022 to February 2023 after getting the clearance from institutional ethics committee. Based on the prevalence of any mental health disorders in India as per National Mental Health Survey (2015-2016) as 10% with alpha error of 5% with 95% confidence interval the minimum sample size calculated was 144 [calculated by Open Epi version 3.01]. For this study, households served as the sample unit. All data was inserted in Microsoft office excel sheet, investigated by SPSS v 22 (IBM Corp). The t-test and the “ANOVA test”, with significance level being defined as “p < 0.05”, was used to find out whether there was significant mean difference between 2 or more groups in perceived stress. Linear regression was performed to find out how much the various factors can predict the perceived stress scores. The univariate analysis showed that habits of smoking, alcoholism, occupation, and socioeconomic status were the factors which can predict the perceived stress levels. When multiple linear regression was done, only the SES was predicting the perceived stress levels. Higher the SES lesser the perceived stress levels. Perceived stress in low socioeconomic status was high with habit of smoking, alcoholism, marital status, and occupation being its covariates. Future research must evaluate the social networks' role in Indian environment as a means of dealing with perceived stress. Keywords: Perceived stress, Urban Population, PSS­10 scale
在发展中国家,不断增长的压力是身体和情感紧张未解决的标志。长期的压力对一个人的健康和幸福有不利的影响。关于印度普通人群的感知压力水平及其相关因素的数据很少。评估甘地那格尔城市人口的感知压力水平及其相关因素。数据收集来自科拉尔甘地纳加尔城市野外实践区的居民。数据收集使用了预先测试的半结构化问卷。这些房屋是通过系统随机选择来选择的。研究设计为基于社区的横断面研究。采用PSS-10量表评估感知压力。该研究在得到伦理委员会的批准后,于2022年10月至2023年2月进行。根据国家心理健康调查(2015-2016),印度任何精神健康障碍的患病率为10%,alpha误差为5%,95%置信区间,计算出的最小样本量为144[由Open Epi 3.01版计算]。本研究以家庭为样本单位。所有数据在Microsoft office excel表格中插入,用SPSS v 22 (IBM Corp .)进行调查。采用t检验和“ANOVA检验”,显著性水平定义为“p < 0.05”,以确定两组或两组以上的感知压力是否有显著的平均差异。通过线性回归分析各因素对感知压力得分的预测作用。单因素分析显示,吸烟习惯、酗酒习惯、职业和社会经济地位是预测感知压力水平的因素。当多元线性回归时,只有SES能预测感知压力水平。社会经济地位越高,感知到的压力水平越低。社会经济地位低者的感知压力高,其协变量为吸烟习惯、酗酒、婚姻状况和职业。未来的研究必须评估社会网络作为一种处理感知压力的手段在印度环境中的作用。关键词:感知压力,城市人口,PSS-10量表
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引用次数: 0
Bilirubin in Diabetic Retinopathy: Too Little or Too Much? 胆红素在糖尿病视网膜病变中的作用:过少还是过多?
Pub Date : 2023-09-12 DOI: 10.58739/jcbs/v13i2.23.11
R Harish, K N Shashidhar
Diabetic retinopathy (DR) is a significant diabetic complication that may result in loss of vision and blindness. The development of DR is intricate and encompasses numerous processes, such as oxidative stress. Bilirubin, a powerful antioxidant, has been proposed as a probable indicator for oxidative stress in DR. Bilirubin is a powerful antioxidant that helps to eliminate free radicals and other reactive oxygen species (ROS) in the body by being produced during the breakdown of heme. Additionally, it aids in the regulation of the expression of antioxidant genes, further bolstering its antioxidant properties. Therefore, bilirubin plays a crucial role in safeguarding cells from oxidative stress. Oxidative stress arises when there is an imbalance between ROS production and the body's ability to detoxify them. This can result in oxidative damage to cellular components like proteins, lipids, and DNA. Oxidative stress has been implicated in the development of various ailments, including Diabetic Retinopathy (DR). Keywords: Bilirubin, Diabetic retinopathy, Oxidative stress
糖尿病视网膜病变(DR)是一种重要的糖尿病并发症,可导致视力丧失和失明。DR的发展是复杂的,包括许多过程,如氧化应激。胆红素是一种强大的抗氧化剂,已被认为是dr氧化应激的可能指标。胆红素是一种强大的抗氧化剂,通过在血红素分解过程中产生,有助于消除体内自由基和其他活性氧(ROS)。此外,它有助于调节抗氧化基因的表达,进一步增强其抗氧化性能。因此,胆红素在保护细胞免受氧化应激方面起着至关重要的作用。当活性氧产生和身体解毒能力不平衡时,氧化应激就会出现。这会导致细胞成分如蛋白质、脂质和DNA的氧化损伤。氧化应激与各种疾病的发展有关,包括糖尿病视网膜病变(DR)。关键词:胆红素,糖尿病视网膜病变,氧化应激
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引用次数: 0
Dermatology Photo Quiz – 4 皮肤病学照片测验- 4
Pub Date : 2023-09-12 DOI: 10.58739/jcbs/v13i2.23.28
T S Rajashekar, Kumar K Suresh, P V Swathi, Chris R Jervin, S Samhith, Y Sushmitha, K Hanumanthayya
Basal Cell Carcinoma (BCC) is slow growing and less discomforting lesion. BCC is usually seen on upper part of the face (A line drawn from the angle of mouth to tragus of the ear). As the lesion is less symptomatic, patients do not come forward for treatment. Pain and itching are the greatest gift of the God. People seek treatment, if they get discomfort in the lesion either in the form of pain or itching. This patient is 75-year-old man, illiterate and do not give importance to his external appearance, all the time he will be thinking of going to field, grow the crops, and feed himself and his dependents. As he fell down and injured the lesion, he was forced to come major hospital for treatment. The reason for not giving importance to his external appearance is because of his poverty and illiteracy which makes him work tirelessly for his and his family to meet his daily needs. Keywords: BCC, Tumor cells, Basal cells
基底细胞癌(BCC)是一种生长缓慢且不易引起不适的病变。BCC通常见于面部上半部分(从嘴角到耳屏的一条线)。由于病变症状较轻,患者不前来治疗。疼痛和瘙痒是上帝给我们最好的礼物。如果病变部位出现疼痛或瘙痒等不适,人们就会寻求治疗。这个病人是一个75岁的男人,文盲,不重视他的外表,他总是想着去田里,种庄稼,养活自己和他的家属。由于摔倒伤了皮损,他被迫来到大医院接受治疗。他不重视外表的原因是因为他的贫穷和文盲,这使得他不知疲倦地为他和他的家人工作,以满足他的日常需求。关键词:基底细胞癌,肿瘤细胞,基底细胞
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引用次数: 0
A multifaceted Investigation Saga of an Sordid Act of Mariticide - A Case Report 一个肮脏的杀人行为的多方面调查传奇-一个案例报告
Pub Date : 2023-09-12 DOI: 10.58739/jcbs/v13i2.23.23
R Abhinandana, Rajkumar Rajkumar
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引用次数: 0
Effectiveness of Tailored Exercise Protocol on Functional Independence in Post Laminectomy Induced Paraparesis – A Case Study 量身定制的运动方案对椎板切除术后诱发截瘫的功能独立性的有效性-一个案例研究
Pub Date : 2023-05-30 DOI: 10.58739/jcbs/v13i1.23.1
Krishna Anand, Kavitha Rani N
The compression and decompression junction are a potential site for spinal cord distortion. Cord compression could result from the changed cerebrospinal fluid flow dynamics. Para paresis will occur due to direct trauma sustained during surgery or postoperative hematomas and there is 16% of secondary disease, because of non-traumatic injuries and 84% of spinal cord injury are due to trauma and 2 to 5 times the individuals will die prematurely due to spinal cord injury. Case report of a patient, having D8-L1 wedge compression fracture undergone surgical laminectomy, for which specific exercise protocol designed to improve muscle strength, activities of daily living and reduce clonus. post-operatively patient complained of weakness in bilateral lower limb, and he was dependent on others for his daily life activities, so our aim was to make the patient independent and he should be able to transfer from bed to wheelchair and reduce clonus. Tailored protocol was designed for patient’s functional independence by bed mobility, transfer skills, muscle strengthening by using different scales, and he was trained five sessions in a week for three months. After implementing the exercise program like strengthening exercises for bilateral upper limbs, bed mobility training, stretching of bilateral lower limb muscles for clonus and transfer skills using tailored protocol for twelve weeks there was improvement in all parameters. Keywords: Paraplegia, Functional independence, Tailored exercise
压缩和减压连接处是脊髓变形的潜在部位。脑脊液流动动力学的改变可能导致脊髓受压。由于手术中持续的直接创伤或术后血肿会导致瘫瘫,继发性疾病的16%,因为非创伤性损伤和84%的脊髓损伤是由于创伤造成的,2至5倍的个体会因脊髓损伤而过早死亡。1例D8-L1楔形压缩性骨折患者行椎板切除术的病例报告,针对该患者设计了特定的运动方案,以提高肌力、日常生活活动能力和减少结痂。术后患者主诉双侧下肢无力,日常生活活动依赖他人,我们的目标是使患者能够独立,能够从床上移到轮椅上,减少结痂。针对患者的功能独立性,通过床上活动、转移技能、肌肉强化等不同尺度设计了量身定制的方案,每周训练5次,持续3个月。在实施了锻炼计划,如加强双侧上肢的锻炼,床上活动训练,伸展双侧下肢肌肉的clonus和使用量身定制的方案转移技能12周后,所有参数都有所改善。关键词:截瘫,功能独立,针对性运动
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引用次数: 0
Dermatology Photo Quiz 2 皮肤病学照片测验2
Pub Date : 2023-05-21 DOI: 10.58739/jcbs/v13i1.22.125
Rajashekar T S, Suresh Kumar K, Vaishnavi B V, Anjana G, Shiva Saadhvi M, Harihara Subramanian M, Hanumanthayya K
40-year-old male, married, and sexually active gentleman, had un-protected sex with other woman, after 5 days, he noticed painful ulcers on his penis. He came to hospital, examination revealed, painful ulcers on glans penis and inner layer of prepuce, with regional lymph node enlargement. Routine and specific investigations were done. Treatment was given, after 10 days, ulcers healed. Genital hygiene and counselling were done, and asked the gentleman to come for regular check-up. Keywords: STD, Chancroid, H ducreyi
40岁男性,已婚,性活跃,与其他女性发生无保护措施的性行为,5天后,他发现阴茎溃疡疼痛。他来到医院,检查显示,阴茎头和包皮内层溃疡疼痛,伴有局部淋巴结肿大。进行了例行和具体的调查。给予治疗,10天后,溃疡愈合。完成了生殖器卫生和咨询,并要求这位先生定期来检查。关键词:性病;软下疳
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引用次数: 0
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