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Medication for Opioid Use Disorder During Pregnancy - Maternal and Infant Network to Understand Outcomes Associated with Use of Medication for Opioid Use Disorder During Pregnancy (MAT-LINK), 2014-2021. 妊娠期阿片类药物使用紊乱--了解妊娠期阿片类药物使用紊乱相关结果的母婴网络(MAT-LINK),2014-2021 年。
IF 37.3 1区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-05-05 DOI: 10.15585/mmwr.ss7203a1
Kathryn Miele, Shin Y Kim, Rachelle Jones, Juneka H Rembert, Elisha M Wachman, Hira Shrestha, Michelle L Henninger, Teresa M Kimes, Patrick D Schneider, Vaseekaran Sivaloganathan, Katherine A Sward, Vikrant G Deshmukh, Pilar M Sanjuan, Jessie R Maxwell, Neil S Seligman, Sarah Caveglia, Judette M Louis, Tanner Wright, Carolyne Cody Bennett, Caitlin Green, Nisha George, Lucas Gosdin, Emmy L Tran, Dana Meaney-Delman, Suzanne M Gilboa

Problem: Medication for opioid use disorder (MOUD) is recommended for persons with opioid use disorder (OUD) during pregnancy. However, knowledge gaps exist about best practices for management of OUD during pregnancy and these data are needed to guide clinical care.

Period covered: 2014-2021.

Description of the system: Established in 2019, the Maternal and Infant Network to Understand Outcomes Associated with Medication for Opioid Use Disorder During Pregnancy (MAT-LINK) is a surveillance network of seven clinical sites in the United States. Boston Medical Center, Kaiser Permanente Northwest, The Ohio State University, and the University of Utah were the initial clinical sites in 2019. In 2021, three clinical sites were added to the network (the University of New Mexico, the University of Rochester, and the University of South Florida). Persons receiving care at the seven clinical sites are diverse in terms of geography, urbanicity, race and ethnicity, insurance coverage, and type of MOUD received. The goal of MAT-LINK is to capture demographic and clinical information about persons with OUD during pregnancy to better understand the effect of MOUD on outcomes and, ultimately, provide information for clinical care and public health interventions for this population. MAT-LINK maintains strict confidentiality through robust information technology architecture. MAT-LINK surveillance methods, population characteristics, and evaluation findings are described in this inaugural surveillance report. This report is the first to describe the system, presenting detailed information on funding, structure, data elements, and methods as well as findings from a surveillance evaluation. The findings presented in this report are limited to selected demographic characteristics of pregnant persons overall and by MOUD treatment status. Clinical and outcome data are not included because data collection and cleaning have not been completed; initial analyses of clinical and outcome data will begin in 2023.

Results: The MAT-LINK surveillance network gathered data on 5,541 reported pregnancies with a known pregnancy outcome during 2014-2021 among persons with OUD from seven clinical sites. The mean maternal age was 29.7 (SD = ±5.1) years. By race and ethnicity, 86.3% of pregnant persons were identified as White, 25.4% as Hispanic or Latino, and 5.8% as Black or African American. Among pregnant persons, 81.6% had public insurance, and 84.4% lived in urban areas. Compared with persons not receiving MOUD during pregnancy, those receiving MOUD during pregnancy were more likely to be older and White and to have public insurance. The evaluation of the surveillance system found that the initial four clinical sites were not representative of demographics of the South or Southwest regions of the United States and had low representation from certain racial and ethnic groups compared with the ov

问题:建议妊娠期阿片类药物使用障碍(OUD)患者服用治疗阿片类药物使用障碍(MOUD)的药物。然而,关于孕期阿片类药物使用障碍管理的最佳实践还存在知识差距,需要这些数据来指导临床护理:了解孕期阿片类药物使用障碍相关结果的母婴网络(MAT-LINK)成立于 2019 年,是一个由美国 7 个临床站点组成的监测网络。波士顿医疗中心、西北凯撒医疗集团、俄亥俄州立大学和犹他大学是 2019 年的首批临床基地。2021 年,该网络又增加了三个临床站点(新墨西哥大学、罗切斯特大学和南佛罗里达大学)。在这七个临床基地接受治疗的人在地理位置、城市化程度、种族和民族、保险覆盖率以及接受的 MOUD 类型等方面各不相同。MAT-LINK 的目标是收集孕期 OUD 患者的人口统计和临床信息,以便更好地了解 MOUD 对治疗效果的影响,最终为这一人群的临床治疗和公共卫生干预提供信息。MAT-LINK 通过强大的信息技术架构严格保密。MAT-LINK 监测方法、人群特征和评估结果将在这份首次监测报告中进行介绍。本报告是第一份描述该系统的报告,详细介绍了该系统的资金、结构、数据元素和方法,以及监测评估结果。本报告中介绍的结果仅限于孕妇的总体人口统计特征和 MOUD 治疗状况。由于数据收集和清理工作尚未完成,因此不包括临床和结果数据;临床和结果数据的初步分析将于 2023 年开始:MAT-LINK监测网络收集了2014-2021年期间来自7个临床站点的5,541例已知妊娠结果的OUD患者的妊娠报告数据。产妇的平均年龄为 29.7 岁(SD = ±5.1)。按种族和民族划分,86.3% 的孕妇被认定为白人,25.4% 被认定为西班牙裔或拉丁裔,5.8% 被认定为黑人或非裔美国人。在孕妇中,81.6%有公共保险,84.4%居住在城市地区。与怀孕期间未接受钼靶治疗的人相比,怀孕期间接受钼靶治疗的人更有可能是老年人、白人和有公共保险的人。对监测系统的评估发现,最初的四个临床站点不能代表美国南部或西南部地区的人口构成,与美国总人口相比,某些种族和民族群体的代表性较低;然而,2021 年新增的三个临床站点使监测网络更具代表性。自动提取和处理提高了数据收集和分析的速度。MAT-LINK能够增加新的临床站点和变量,这充分体现了MAT-LINK的灵活性:MAT-LINK是首个从多个临床站点收集与妊娠期MOUD相关的围产期结局的孕妇-婴儿二人组综合纵向数据的监测系统。对临床地点数据的分析表明,MOUD 治疗组和非 MOUD 治疗组之间存在不同的社会人口特征:公共卫生行动:MAT-LINK 是一个及时、灵活的监测系统,拥有约 5,500 例妊娠的数据。持续的数据收集和分析将为临床和公共卫生指导提供信息支持,以改善患有 OUD 的孕妇及其子女的健康状况。
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引用次数: 0
Early Identification of Autism Spectrum Disorder Among Children Aged 4 Years - Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2020. 4岁儿童自闭症谱系障碍的早期识别——自闭症与发育障碍监测网络,美国,2020。
IF 37.3 1区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-03-24 DOI: 10.15585/mmwr.ss7201a1
Kelly A Shaw, Deborah A Bilder, Dedria McArthur, Ashley Robinson Williams, Esther Amoakohene, Amanda V Bakian, Maureen S Durkin, Robert T Fitzgerald, Sarah M Furnier, Michelle M Hughes, Elise T Pas, Angelica Salinas, Zachary Warren, Susan Williams, Amy Esler, Andrea Grzybowski, Christine M Ladd-Acosta, Mary Patrick, Walter Zahorodny, Katie K Green, Jennifer Hall-Lande, Maya Lopez, Kristen Clancy Mancilla, Ruby H N Nguyen, Karen Pierce, Yvette D Schwenk, Josephine Shenouda, Kate Sidwell, Alison Vehorn, Monica DiRienzo, Johanna Gutierrez, Libby Hallas, Allison Hudson, Margaret H Spivey, Sydney Pettygrove, Anita Washington, Matthew J Maenner
<p><strong>Problem/condition: </strong>Autism spectrum disorder (ASD).</p><p><strong>Period covered: </strong>2020.</p><p><strong>Description of system: </strong>The Autism and Developmental Disabilities Monitoring Network is an active surveillance program that estimates prevalence and characteristics of ASD and monitors timing of ASD identification among children aged 4 and 8 years. In 2020, a total of 11 sites (located in Arizona, Arkansas, California, Georgia, Maryland, Minnesota, Missouri, New Jersey, Tennessee, Utah, and Wisconsin) conducted surveillance of ASD among children aged 4 and 8 years and suspected ASD among children aged 4 years. Surveillance included children who lived in the surveillance area at any time during 2020. Children were classified as having ASD if they ever received 1) an ASD diagnostic statement in an evaluation, 2) a special education classification of autism (eligibility), or 3) an ASD International Classification of Diseases (ICD) code (revisions 9 or 10). Children aged 4 years were classified as having suspected ASD if they did not meet the case definition for ASD but had a documented qualified professional's statement indicating a suspicion of ASD. This report focuses on children aged 4 years in 2020 compared with children aged 8 years in 2020.</p><p><strong>Results: </strong>For 2020, ASD prevalence among children aged 4 years varied across sites, from 12.7 per 1,000 children in Utah to 46.4 in California. The overall prevalence was 21.5 and was higher among boys than girls at every site. Compared with non-Hispanic White children, ASD prevalence was 1.8 times as high among Hispanic, 1.6 times as high among non-Hispanic Black, 1.4 times as high among Asian or Pacific Islander, and 1.2 times as high among multiracial children. Among the 58.3% of children aged 4 years with ASD and information on intellectual ability, 48.5% had an IQ score of ≤70 on their most recent IQ test or an examiner's statement of intellectual disability. Among children with a documented developmental evaluation, 78.0% were evaluated by age 36 months. Children aged 4 years had a higher cumulative incidence of ASD diagnosis or eligibility by age 48 months compared with children aged 8 years at all sites; risk ratios ranged from 1.3 in New Jersey and Utah to 2.0 in Tennessee. In the 6 months before the March 2020 COVID-19 pandemic declaration by the World Health Organization, there were 1,593 more evaluations and 1.89 more ASD identifications per 1,000 children aged 4 years than children aged 8 years received 4 years earlier. After the COVID-19 pandemic declaration, this pattern reversed: in the 6 months after pandemic onset, there were 217 fewer evaluations and 0.26 fewer identifications per 1,000 children aged 4 years than children aged 8 years received 4 years earlier. Patterns of evaluation and identification varied among sites, but there was not recovery to pre-COVID-19 pandemic levels by the end of 2020 at most sites or overall. For 2020
问题/状况:自闭症谱系障碍(ASD)。涵盖时间:2020年。系统描述:自闭症和发育障碍监测网络是一个主动监测项目,用于估计自闭症谱系障碍的患病率和特征,并监测4至8岁儿童自闭症谱系障碍的识别时间。2020年,共有11个地点(位于亚利桑那州、阿肯色州、加利福尼亚州、佐治亚州、马里兰州、明尼苏达州、密苏里州、新泽西州、田纳西州、犹他州和威斯康星州)对4岁和8岁儿童的ASD和4岁儿童的疑似ASD进行了监测。监测对象包括2020年期间任何时间居住在监测区内的儿童。如果儿童曾经收到1)评估中的ASD诊断声明,2)自闭症的特殊教育分类(资格),或3)ASD国际疾病分类(ICD)代码(修订版9或10),则将其归类为患有ASD。如果4岁的儿童不符合ASD的病例定义,但有合格的专业人员的书面声明表明怀疑患有ASD,则将其归类为疑似ASD。本报告重点关注2020年4岁儿童与2020年8岁儿童的对比。结果:2020年,不同地区4岁儿童的ASD患病率各不相同,从犹他州的12.7 / 1000到加利福尼亚州的46.4 / 1000。总体患病率为21.5,各地点男孩的患病率均高于女孩。与非西班牙裔白人儿童相比,西班牙裔儿童的ASD患病率是非西班牙裔白人儿童的1.8倍,非西班牙裔黑人儿童的1.6倍,亚洲或太平洋岛民儿童的1.4倍,多种族儿童的1.2倍。在58.3%的4岁儿童ASD和智力信息中,48.5%的儿童在最近的智商测试或考官智力残疾声明中智商得分≤70分。在有发育评估记录的儿童中,78.0%在36个月前进行了评估。与8岁儿童相比,4岁儿童在48个月时ASD诊断或资格的累积发生率更高;风险比从新泽西州和犹他州的1.3到田纳西州的2.0不等。在世界卫生组织宣布2020年3月COVID-19大流行之前的6个月里,与4年前相比,每1000名4岁儿童中接受评估的人数增加了1593人,每1000名8岁儿童中有1.89人被诊断为ASD。在宣布COVID-19大流行后,这种模式发生了逆转:在大流行发生后的6个月内,与4年前相比,每1000名4岁儿童接受的评估减少了217次,每1000名4岁儿童接受的鉴定减少了0.26次。各站点的评估和识别模式各不相同,但到2020年底,大多数站点或总体上都没有恢复到covid -19大流行前的水平。2020年,每1000名4岁儿童中疑似ASD的患病率从0.5(加利福尼亚州)到10.4(阿肯色州)不等,五个地区(亚利桑那州、阿肯色州、马里兰州、新泽西州和犹他州)的患病率较2018年有所增加。4岁疑似ASD儿童的人口学特征和认知特征与4岁ASD儿童相似。解释:观察到4岁前ASD的大范围患病率,表明社区之间早期ASD识别实践存在差异。2020年,在所有地区,4岁儿童中48月龄ASD的累积发病率高于8岁儿童,这表明ASD的早期识别有所改善。在2020年COVID-19大流行爆发之前,4岁儿童的评估次数和诊断率明显较高。在大流行爆发后,大多数地点的ASD评估和识别水平持续较低,这可能表明,到2020年底,卫生服务提供者和学校的评估和识别的典型做法将中断。恢复程度较高的站点可能表明减少服务中断的成功战略,例如转向远程保健方法进行评估。公共卫生行动:从2016年到2020年2月,4岁儿童队列中的ASD评估和识别超过了4年前(从2012年到2016年3月)的8岁儿童队列中的ASD评估和识别。从2016年到2020年3月,4岁儿童的ASD评估和识别在2020年超过了2012年至2016年3月的8岁儿童。与2019冠状病毒病大流行开始同时发生的评估中断以及2020年疑似ASD患病率的增加可能导致ASD识别和干预措施的延误。 随着受影响群体中的儿童年龄的增长,社区可以评估这些中断的影响,并考虑减轻未来突发公共卫生事件造成的服务中断的战略。
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引用次数: 0
Prevalence and Characteristics of Autism Spectrum Disorder Among Children Aged 8 Years - Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2020. 自闭症谱系障碍在 8 岁儿童中的患病率和特征 - 自闭症和发育障碍监测网络,11 个站点,美国,2020 年。
IF 24.9 1区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-03-24 DOI: 10.15585/mmwr.ss7202a1
Matthew J Maenner, Zachary Warren, Ashley Robinson Williams, Esther Amoakohene, Amanda V Bakian, Deborah A Bilder, Maureen S Durkin, Robert T Fitzgerald, Sarah M Furnier, Michelle M Hughes, Christine M Ladd-Acosta, Dedria McArthur, Elise T Pas, Angelica Salinas, Alison Vehorn, Susan Williams, Amy Esler, Andrea Grzybowski, Jennifer Hall-Lande, Ruby H N Nguyen, Karen Pierce, Walter Zahorodny, Allison Hudson, Libby Hallas, Kristen Clancy Mancilla, Mary Patrick, Josephine Shenouda, Kate Sidwell, Monica DiRienzo, Johanna Gutierrez, Margaret H Spivey, Maya Lopez, Sydney Pettygrove, Yvette D Schwenk, Anita Washington, Kelly A Shaw

Problem/condition: Autism spectrum disorder (ASD).

Period covered: 2020.

Description of system: The Autism and Developmental Disabilities Monitoring (ADDM) Network is an active surveillance program that provides estimates of the prevalence of ASD among children aged 8 years. In 2020, there were 11 ADDM Network sites across the United States (Arizona, Arkansas, California, Georgia, Maryland, Minnesota, Missouri, New Jersey, Tennessee, Utah, and Wisconsin). To ascertain ASD among children aged 8 years, ADDM Network staff review and abstract developmental evaluations and records from community medical and educational service providers. A child met the case definition if their record documented 1) an ASD diagnostic statement in an evaluation, 2) a classification of ASD in special education, or 3) an ASD International Classification of Diseases (ICD) code.

Results: For 2020, across all 11 ADDM sites, ASD prevalence per 1,000 children aged 8 years ranged from 23.1 in Maryland to 44.9 in California. The overall ASD prevalence was 27.6 per 1,000 (one in 36) children aged 8 years and was 3.8 times as prevalent among boys as among girls (43.0 versus 11.4). Overall, ASD prevalence was lower among non-Hispanic White children (24.3) and children of two or more races (22.9) than among non-Hispanic Black or African American (Black), Hispanic, and non-Hispanic Asian or Pacific Islander (A/PI) children (29.3, 31.6, and 33.4 respectively). ASD prevalence among non-Hispanic American Indian or Alaska Native (AI/AN) children (26.5) was similar to that of other racial and ethnic groups. ASD prevalence was associated with lower household income at three sites, with no association at the other sites.Across sites, the ASD prevalence per 1,000 children aged 8 years based exclusively on documented ASD diagnostic statements was 20.6 (range = 17.1 in Wisconsin to 35.4 in California). Of the 6,245 children who met the ASD case definition, 74.7% had a documented diagnostic statement of ASD, 65.2% had a documented ASD special education classification, 71.6% had a documented ASD ICD code, and 37.4% had all three types of ASD indicators. The median age of earliest known ASD diagnosis was 49 months and ranged from 36 months in California to 59 months in Minnesota.Among the 4,165 (66.7%) children with ASD with information on cognitive ability, 37.9% were classified as having an intellectual disability. Intellectual disability was present among 50.8% of Black, 41.5% of A/PI, 37.8% of two or more races, 34.9% of Hispanic, 34.8% of AI/AN, and 31.8% of White children with ASD. Overall, children with intellectual disability had earlier median ages of ASD diagnosis (43 months) than those without intellectual disability (53 months).

Interpretation: For 2020, one in 36 children aged 8 years (approximately 4% of boys and 1% of girls) was estimated to have ASD. These estimates are

问题/条件:自闭症谱系障碍(ASD):自闭症谱系障碍 (ASD).覆盖时期:2020 年.系统描述:自闭症和发育障碍监测(ADDM)网络是一项积极的监测计划,提供8岁儿童中自闭症谱系障碍患病率的估计值。2020 年,全美共有 11 个 ADDM 网络站点(亚利桑那州、阿肯色州、加利福尼亚州、佐治亚州、马里兰州、明尼苏达州、密苏里州、新泽西州、田纳西州、犹他州和威斯康星州)。为了确定 8 岁儿童是否患有 ASD,ADDM 网络的工作人员从社区医疗和教育服务提供者处审查和摘录发育评估和记录。如果儿童的记录中包含:1)评估中的 ASD 诊断声明;2)特殊教育中的 ASD 分类;或 3)ASD 国际疾病分类 (ICD) 代码,则该儿童符合病例定义:2020 年,在所有 11 个 ADDM 站点中,每千名 8 岁儿童的 ASD 患病率从马里兰州的 23.1 到加利福尼亚州的 44.9 不等。每 1000 名 8 岁儿童中 ASD 的总体患病率为 27.6(每 36 人中有 1 人),男孩的患病率是女孩的 3.8 倍(43.0 对 11.4)。总体而言,非西班牙裔白人儿童(24.3)和两个或两个以上种族儿童(22.9)的 ASD 患病率低于非西班牙裔黑人或非裔美国人(黑人)、西班牙裔和非西班牙裔亚裔或太平洋岛民(A/PI)儿童(分别为 29.3、31.6 和 33.4)。非西班牙裔美国印第安人或阿拉斯加原住民(AI/AN)儿童的 ASD 患病率(26.5)与其他种族和族裔群体的患病率相似。在三个研究地点,ASD发病率与较低的家庭收入有关,而在其他研究地点则没有关联。在所有研究地点,每千名8岁儿童中完全基于有据可查的ASD诊断陈述的ASD发病率为20.6(范围=威斯康星州的17.1至加利福尼亚州的35.4)。在符合 ASD 病例定义的 6,245 名儿童中,74.7% 有 ASD 诊断陈述记录,65.2% 有 ASD 特殊教育分类记录,71.6% 有 ASD ICD 编码记录,37.4% 有所有三种 ASD 指标。最早确诊 ASD 的年龄中位数为 49 个月,从加利福尼亚州的 36 个月到明尼苏达州的 59 个月不等。在 4,165 名(66.7%)有认知能力信息的 ASD 儿童中,37.9% 被归类为智力残疾。在患有 ASD 的儿童中,50.8% 的黑人儿童、41.5% 的 A/PI 儿童、37.8% 的两个或两个以上种族儿童、34.9% 的西班牙裔儿童、34.8% 的美国原住民/印第安人儿童和 31.8% 的白人儿童患有智力障碍。总体而言,智障儿童确诊 ASD 的中位年龄(43 个月)早于非智障儿童(53 个月):据估计,2020 年每 36 名 8 岁儿童中就有一名(约占男孩的 4%,女孩的 1%)患有 ASD。这些估计值高于 2000-2018 年期间 ADDM 网络的先前估计值。在 8 岁儿童中,白人儿童的 ASD 患病率首次低于其他种族和族裔群体,扭转了过去观察到的 ASD 患病率种族和族裔差异的方向。患有自闭症的黑人儿童仍比患有自闭症的白人儿童更有可能同时患有智力残疾:被确认患有 ASD 的儿童人数持续增加,尤其是非白人儿童和女童,这突出表明需要加强基础设施建设,为所有患有 ASD 的儿童提供公平的诊断、治疗和支持服务。与之前的报告期类似,各网络站点的研究结果差异很大,这表明有必要开展更多研究,以了解这些差异的性质,并有可能在各州应用成功的识别策略。
{"title":"Prevalence and Characteristics of Autism Spectrum Disorder Among Children Aged 8 Years - Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2020.","authors":"Matthew J Maenner, Zachary Warren, Ashley Robinson Williams, Esther Amoakohene, Amanda V Bakian, Deborah A Bilder, Maureen S Durkin, Robert T Fitzgerald, Sarah M Furnier, Michelle M Hughes, Christine M Ladd-Acosta, Dedria McArthur, Elise T Pas, Angelica Salinas, Alison Vehorn, Susan Williams, Amy Esler, Andrea Grzybowski, Jennifer Hall-Lande, Ruby H N Nguyen, Karen Pierce, Walter Zahorodny, Allison Hudson, Libby Hallas, Kristen Clancy Mancilla, Mary Patrick, Josephine Shenouda, Kate Sidwell, Monica DiRienzo, Johanna Gutierrez, Margaret H Spivey, Maya Lopez, Sydney Pettygrove, Yvette D Schwenk, Anita Washington, Kelly A Shaw","doi":"10.15585/mmwr.ss7202a1","DOIUrl":"10.15585/mmwr.ss7202a1","url":null,"abstract":"<p><strong>Problem/condition: </strong>Autism spectrum disorder (ASD).</p><p><strong>Period covered: </strong>2020.</p><p><strong>Description of system: </strong>The Autism and Developmental Disabilities Monitoring (ADDM) Network is an active surveillance program that provides estimates of the prevalence of ASD among children aged 8 years. In 2020, there were 11 ADDM Network sites across the United States (Arizona, Arkansas, California, Georgia, Maryland, Minnesota, Missouri, New Jersey, Tennessee, Utah, and Wisconsin). To ascertain ASD among children aged 8 years, ADDM Network staff review and abstract developmental evaluations and records from community medical and educational service providers. A child met the case definition if their record documented 1) an ASD diagnostic statement in an evaluation, 2) a classification of ASD in special education, or 3) an ASD International Classification of Diseases (ICD) code.</p><p><strong>Results: </strong>For 2020, across all 11 ADDM sites, ASD prevalence per 1,000 children aged 8 years ranged from 23.1 in Maryland to 44.9 in California. The overall ASD prevalence was 27.6 per 1,000 (one in 36) children aged 8 years and was 3.8 times as prevalent among boys as among girls (43.0 versus 11.4). Overall, ASD prevalence was lower among non-Hispanic White children (24.3) and children of two or more races (22.9) than among non-Hispanic Black or African American (Black), Hispanic, and non-Hispanic Asian or Pacific Islander (A/PI) children (29.3, 31.6, and 33.4 respectively). ASD prevalence among non-Hispanic American Indian or Alaska Native (AI/AN) children (26.5) was similar to that of other racial and ethnic groups. ASD prevalence was associated with lower household income at three sites, with no association at the other sites.Across sites, the ASD prevalence per 1,000 children aged 8 years based exclusively on documented ASD diagnostic statements was 20.6 (range = 17.1 in Wisconsin to 35.4 in California). Of the 6,245 children who met the ASD case definition, 74.7% had a documented diagnostic statement of ASD, 65.2% had a documented ASD special education classification, 71.6% had a documented ASD ICD code, and 37.4% had all three types of ASD indicators. The median age of earliest known ASD diagnosis was 49 months and ranged from 36 months in California to 59 months in Minnesota.Among the 4,165 (66.7%) children with ASD with information on cognitive ability, 37.9% were classified as having an intellectual disability. Intellectual disability was present among 50.8% of Black, 41.5% of A/PI, 37.8% of two or more races, 34.9% of Hispanic, 34.8% of AI/AN, and 31.8% of White children with ASD. Overall, children with intellectual disability had earlier median ages of ASD diagnosis (43 months) than those without intellectual disability (53 months).</p><p><strong>Interpretation: </strong>For 2020, one in 36 children aged 8 years (approximately 4% of boys and 1% of girls) was estimated to have ASD. These estimates are ","PeriodicalId":48549,"journal":{"name":"Mmwr Surveillance Summaries","volume":"72 2","pages":"1-14"},"PeriodicalIF":24.9,"publicationDate":"2023-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042614/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9265448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abortion Surveillance - United States, 2020. 堕胎监控 - 美国,2020 年。
IF 37.3 1区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-11-25 DOI: 10.15585/mmwr.ss7110a1
Katherine Kortsmit, Antoinette T Nguyen, Michele G Mandel, Elizabeth Clark, Lisa M Hollier, Jessica Rodenhizer, Maura K Whiteman
<p><strong>Problem/condition: </strong>CDC conducts abortion surveillance to document the number and characteristics of women obtaining legal induced abortions and number of abortion-related deaths in the United States.</p><p><strong>Period covered: </strong>2020.</p><p><strong>Description of system: </strong>Each year, CDC requests abortion data from the central health agencies for the 50 states, the District of Columbia, and New York City. For 2020, a total of 49 reporting areas voluntarily provided aggregate abortion data to CDC. Of these, 48 reporting areas provided data each year during 2011-2020. Census and natality data were used to calculate abortion rates (number of abortions per 1,000 women aged 15-44 years) and ratios (number of abortions per 1,000 live births), respectively. Abortion-related deaths from 2019 were assessed as part of CDC's Pregnancy Mortality Surveillance System (PMSS).</p><p><strong>Results: </strong>A total of 620,327 abortions for 2020 were reported to CDC from 49 reporting areas. Among 48 reporting areas with data each year during 2011-2020, in 2020, a total of 615,911 abortions were reported, the abortion rate was 11.2 abortions per 1,000 women aged 15-44 years, and the abortion ratio was 198 abortions per 1,000 live births. From 2019 to 2020, the total number of abortions decreased 2% (from 625,346 total abortions), the abortion rate decreased 2% (from 11.4 abortions per 1,000 women aged 15-44 years), and the abortion ratio increased 2% (from 195 abortions per 1,000 live births). From 2011 to 2020, the total number of reported abortions decreased 15% (from 727,554), the abortion rate decreased 18% (from 13.7 abortions per 1,000 women aged 15-44 years), and the abortion ratio decreased 9% (from 217 abortions per 1,000 live births).In 2020, women in their 20s accounted for more than half of abortions (57.2%). Women aged 20-24 and 25-29 years accounted for the highest percentages of abortions (27.9% and 29.3%, respectively) and had the highest abortion rates (19.2 and 19.0 abortions per 1,000 women aged 20-24 and 25-29 years, respectively). By contrast, adolescents aged <15 years and women aged ≥40 years accounted for the lowest percentages of abortions (0.2% and 3.7%, respectively) and had the lowest abortion rates (0.4 and 2.6 abortions per 1,000 women aged <15 and ≥40 years, respectively). However, abortion ratios were highest among adolescents (aged ≤19 years) and lowest among women aged 25-39 years.Abortion rates decreased from 2011 to 2020 among all age groups. The decrease in abortion rate was highest among adolescents compared with any other age group. From 2019 to 2020, abortion rates decreased or did not change for all age groups. Abortion ratios decreased from 2011 to 2020 for all age groups, except adolescents aged 15-19 years and women aged 25-29 years for whom abortion ratios increased. The decrease in abortion ratio was highest among women aged ≥40 years compared with any other age group. From 2019 to
问题/条件:疾病预防控制中心对人工流产进行监测,以记录美国合法人工流产妇女的数量和特征,以及与人工流产相关的死亡人数:每年,疾病预防控制中心都会要求 50 个州、哥伦比亚特区和纽约市的中央卫生机构提供堕胎数据。就 2020 年而言,共有 49 个报告地区自愿向疾病预防控制中心提供堕胎综合数据。其中,48 个报告地区在 2011-2020 年期间每年都提供了数据。人口普查和出生率数据分别用于计算堕胎率(每千名 15-44 岁女性的堕胎数)和比率(每千名活产婴儿的堕胎数)。作为疾病预防控制中心妊娠死亡监测系统(PMSS)的一部分,对2019年与人工流产相关的死亡进行了评估:49 个报告地区共向疾病预防控制中心报告了 620,327 例 2020 年人工流产。在 2011-2020 年期间每年都有数据的 48 个报告地区中,2020 年共报告了 615,911 例人工流产,人工流产率为每 1,000 名 15-44 岁女性中有 11.2 例人工流产,人工流产率为每 1,000 例活产中有 198 例人工流产。从 2019 年到 2020 年,堕胎总数减少了 2%(堕胎总数为 625 346 例),堕胎率下降了 2%(每千名 15-44 岁女性的堕胎率为 11.4 例),堕胎率上升了 2%(每千名活产婴儿的堕胎率为 195 例)。从 2011 年到 2020 年,报告的堕胎总数下降了 15%(从 727 554 例下降到 727 554 例),堕胎率下降了 18%(从每千名 15-44 岁妇女 13.7 例堕胎下降到每千名 15-44 岁妇女 13.7 例堕胎),堕胎率下降了 9%(从每千名活产婴儿 217 例堕胎下降到每千名活产婴儿 217 例堕胎)。20-24 岁和 25-29 岁妇女的堕胎比例最高(分别为 27.9% 和 29.3%),堕胎率也最高(每千名 20-24 岁和 25-29 岁妇女的堕胎率分别为 19.2 和 19.0)。相比之下,妊娠 13 周的青少年堕胎率始终较低(≤9.2%)。2020 年,妊娠≤9 周的早期药物流产所占比例最高(51.0%),其次是妊娠≤13 周的手术流产(40.0%)、妊娠>13 周的手术流产(6.7%)和妊娠>9 周的药物流产(2.4%);所有其他方法都不常见(解释:在 48 个连续报告数据的地区中,妊娠≤9 周的早期药物流产所占比例最高(51.0%),其次是妊娠≤13 周的手术流产(40.0%)、妊娠>13 周的手术流产(6.7%)和妊娠>9 周的药物流产(2.4%):在 2011-2020 年间连续报告数据的 48 个地区中,2011-2020 年间报告的堕胎总数、比率和比例总体下降。从 2019 年到 2020 年,报告的堕胎总数和堕胎率也有所下降;但堕胎总比率却上升了 2%:流产监测可用于帮助评估旨在促进美国公平获得以患者为中心的优质避孕服务的计划,以减少意外怀孕。
{"title":"Abortion Surveillance - United States, 2020.","authors":"Katherine Kortsmit, Antoinette T Nguyen, Michele G Mandel, Elizabeth Clark, Lisa M Hollier, Jessica Rodenhizer, Maura K Whiteman","doi":"10.15585/mmwr.ss7110a1","DOIUrl":"10.15585/mmwr.ss7110a1","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Problem/condition: &lt;/strong&gt;CDC conducts abortion surveillance to document the number and characteristics of women obtaining legal induced abortions and number of abortion-related deaths in the United States.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Period covered: &lt;/strong&gt;2020.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Description of system: &lt;/strong&gt;Each year, CDC requests abortion data from the central health agencies for the 50 states, the District of Columbia, and New York City. For 2020, a total of 49 reporting areas voluntarily provided aggregate abortion data to CDC. Of these, 48 reporting areas provided data each year during 2011-2020. Census and natality data were used to calculate abortion rates (number of abortions per 1,000 women aged 15-44 years) and ratios (number of abortions per 1,000 live births), respectively. Abortion-related deaths from 2019 were assessed as part of CDC's Pregnancy Mortality Surveillance System (PMSS).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 620,327 abortions for 2020 were reported to CDC from 49 reporting areas. Among 48 reporting areas with data each year during 2011-2020, in 2020, a total of 615,911 abortions were reported, the abortion rate was 11.2 abortions per 1,000 women aged 15-44 years, and the abortion ratio was 198 abortions per 1,000 live births. From 2019 to 2020, the total number of abortions decreased 2% (from 625,346 total abortions), the abortion rate decreased 2% (from 11.4 abortions per 1,000 women aged 15-44 years), and the abortion ratio increased 2% (from 195 abortions per 1,000 live births). From 2011 to 2020, the total number of reported abortions decreased 15% (from 727,554), the abortion rate decreased 18% (from 13.7 abortions per 1,000 women aged 15-44 years), and the abortion ratio decreased 9% (from 217 abortions per 1,000 live births).In 2020, women in their 20s accounted for more than half of abortions (57.2%). Women aged 20-24 and 25-29 years accounted for the highest percentages of abortions (27.9% and 29.3%, respectively) and had the highest abortion rates (19.2 and 19.0 abortions per 1,000 women aged 20-24 and 25-29 years, respectively). By contrast, adolescents aged &lt;15 years and women aged ≥40 years accounted for the lowest percentages of abortions (0.2% and 3.7%, respectively) and had the lowest abortion rates (0.4 and 2.6 abortions per 1,000 women aged &lt;15 and ≥40 years, respectively). However, abortion ratios were highest among adolescents (aged ≤19 years) and lowest among women aged 25-39 years.Abortion rates decreased from 2011 to 2020 among all age groups. The decrease in abortion rate was highest among adolescents compared with any other age group. From 2019 to 2020, abortion rates decreased or did not change for all age groups. Abortion ratios decreased from 2011 to 2020 for all age groups, except adolescents aged 15-19 years and women aged 25-29 years for whom abortion ratios increased. The decrease in abortion ratio was highest among women aged ≥40 years compared with any other age group. From 2019 to","PeriodicalId":48549,"journal":{"name":"Mmwr Surveillance Summaries","volume":"71 10","pages":"1-27"},"PeriodicalIF":37.3,"publicationDate":"2022-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707346/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10465302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surveillance for Sickle Cell Disease - Sickle Cell Data Collection Program, Two States, 2004-2018. 镰状细胞病监测-镰状细胞数据收集计划,两个州,2004-2018。
IF 24.9 1区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-10-07 DOI: 10.15585/mmwr.ss7109a1
Angela B Snyder, Sangeetha Lakshmanan, Mary M Hulihan, Susan T Paulukonis, Mei Zhou, Sophia S Horiuchi, Karon Abe, Shammara N Pope, Laura A Schieve
<p><strong>Problem/condition: </strong>Sickle cell disease (SCD), an inherited blood disorder affecting an estimated 100,000 persons in the United States, is associated with multiple complications and reduced life expectancy. Complications of SCD can include anemia, debilitating acute and chronic pain, infection, acute chest syndrome, stroke, and progressive organ damage, including decreased cognitive function and renal failure. Early diagnosis, screenings and preventive interventions, and access to specialist health care can decrease illness and death. Population-based public health surveillance is critical to understanding the course and outcomes of SCD as well as the health care use, unmet health care needs, and gaps in essential services of the population affected by SCD.</p><p><strong>Period covered: </strong>2004-2018.</p><p><strong>Description of the program: </strong>In 2015, CDC established the Sickle Cell Data Collection (SCDC) program to characterize the epidemiology of SCD in two states (California and Georgia). Previously, surveillance for SCD was conducted by two short-term projects: Registry and Surveillance System for Hemoglobinopathies (RuSH), which was conducted during 2010-2012 and included 2004-2008 data, and Public Health Research, Epidemiology, and Surveillance for Hemoglobinopathies (PHRESH), which was conducted during 2012-2014 and included 2004-2008 data. Both California and Georgia participated in RuSH and PHRESH, which guided the development of the SCDC methods and case definitions. SCDC is a population-based tracking system that uses comprehensive data linkages in state health systems. These linkages serve to synthesize and disseminate population-based, longitudinal data for persons identified with SCD from multiple sources using selected International Classification of Diseases, Ninth Revision, Clinical Modification, and Tenth Revision codes and laboratory results confirmed through state newborn screening (NBS) programs or clinic case reporting. Administrative and clinical data sources include state Medicaid and Children's Health Insurance Program databases, death certificates, NBS programs, hospital discharge and emergency department records, and clinical records or case reports. Data from multiple sources and years are linked and deduplicated so that states can analyze and report on SCD population prevalence, demographic characteristics, health care access and use, and health outcomes. The SCD case definition is based on an algorithm that classifies cases with laboratory confirmation as confirmed cases and those with a reported clinical diagnosis or three or more diagnostic codes over a 5-year period from an administrative data source as probable cases. In 2019, nine states (Alabama, California, Georgia, Indiana, Michigan, Minnesota, North Carolina, Tennessee, and Virginia) were funded as part of an SCDC capacity-building initiative. The newly funded states developed strategies for SCD case identification and data l
问题/状况:镰状细胞病(SCD)是一种遗传性血液病,在美国约有10万人患病,与多种并发症和预期寿命缩短有关。SCD的并发症可能包括贫血、使人衰弱的急性和慢性疼痛、感染、急性胸部综合征、中风和进行性器官损伤,包括认知功能下降和肾衰竭。早期诊断、筛查和预防性干预以及获得专业医疗保健可以减少疾病和死亡。基于人口的公共卫生监测对于了解SCD的过程和结果,以及受SCD影响的人群的医疗保健使用、未满足的医疗保健需求和基本服务差距至关重要。涵盖时间:2004-2018。项目描述:2015年,美国疾病控制与预防中心建立了镰状细胞数据收集(SCDC)计划,以表征两个州(加利福尼亚州和佐治亚州)的镰状细胞病流行病学。此前,SCD的监测由两个短期项目进行:血红蛋白病登记和监测系统(RuSH),于2010-2012年进行,包括2004-2008年的数据;公共卫生研究、流行病学和血红蛋白病监测(PHRESH),于2012-2014年进行,包括2004-2008年数据。加利福尼亚州和乔治亚州都参与了RuSH和PHRESH,指导了SCDC方法和案例定义的发展。SCDC是一个基于人口的跟踪系统,在州卫生系统中使用全面的数据链接。这些联系有助于综合和传播来自多个来源的SCD患者的基于人群的纵向数据,这些数据使用选定的国际疾病分类、第九次修订、临床修改和第十次修订代码以及通过国家新生儿筛查(NBS)计划或临床病例报告确认的实验室结果。行政和临床数据来源包括州医疗补助和儿童健康保险计划数据库、死亡证明、NBS计划、出院和急诊科记录以及临床记录或病例报告。将来自多个来源和年份的数据联系起来并消除重复,以便各州能够分析和报告SCD人口流行率、人口统计特征、医疗保健的获得和使用以及健康结果。SCD病例定义基于一种算法,该算法将实验室确认的病例分类为确诊病例,并将行政数据源在5年内报告的临床诊断或三个或三个以上诊断代码的病例归类为可能病例。2019年,作为SCDC能力建设倡议的一部分,九个州(阿拉巴马州、加利福尼亚州、佐治亚州、印第安纳州、密歇根州、明尼苏达州、北卡罗来纳州、田纳西州和弗吉尼亚州)获得了资助。新资助的州制定了类似于加利福尼亚州和佐治亚州的SCD病例识别和数据链接策略。截至2021年,SCDC计划已扩展到11个州,增加了科罗拉多州和威斯康星州。结果:2004-2018年,加利福尼亚州和佐治亚州确诊和疑似SCD病例的累计流行率分别为9875例和14777例。2018年加利福尼亚州的年度流行率为6027例,佐治亚州为9141例。2014-2018年期间,通过贡献数据源对流行率计数的检查显示,每个数据源在加利福尼亚州捕获了16%-71%的病例,在佐治亚州捕获了17%-87%的病例;因此,没有任何单独的来源足以估计全州的人口流行率。儿科SCD患者(0-18岁儿童)的比例在加利福尼亚州为27%,在佐治亚州为40%。加利福尼亚州和乔治亚州女性SCD患者的比例分别为58%和57%。在有SCD基因分型数据的病例中(n=5856),63%的患者患有镰状细胞性贫血。SCDC数据已被用于直接向医疗保健提供者和政策制定者通报SCD患者的医疗保健需求和差距。例如,佐治亚州SCDC的一项评估表明,在2004-2016年期间出生的SCD婴儿中,10%的婴儿居住在距离任何SCD专科护理选择超过1小时车程的地方,另有14%的婴儿居住的地方距离定期SCD专科诊所不到1小时车程。同样,SCDC加利福尼亚州的一项评估表明,在2016-2018年期间,洛杉矶县的大多数SCD患者居住在距离有SCD护理经验的血液学家约15-60英里的地方。2020-2021年期间,对所有11个SCDC州的监测能力和性能评估表明,各州在用于SCD监测的数据源的可用性和访问每个州数据源的时间框架方面存在差异。尽管如此,所有参与国都制定了报告标准化的方法。 解读:本报告首次全面描述了美国疾病控制与预防中心与参与州合作,通过SCDC计划建立、维持和扩大SCD监测,以改善SCD患者的健康状况。来自加利福尼亚州和乔治亚州的分析结果强调了增加SCD专科诊所的必要性。尽管采用了不同的方法,但使用所有参与州制定的标准化、严格的方法,报告疾病流行率、医疗保健需求和使用情况以及死亡情况,将SCDC扩展到多个州是可能的。公共卫生行动:监测结果可用于改善和监测SCD患者的护理和结果。这些和其他SCDC分析在开设新的SCD诊所、教育医疗保健提供者、制定州医疗保健政策和指导新的研究举措方面发挥了作用。公共卫生官员可以将这份报告作为指导框架,为SCD患者规划或实施监测计划。与数据相关的活动(数据源;患者标识符;以及获取、传输和链接数据)和行政考虑因素(利益相关者参与、成本和资源以及长期可持续性)对这些计划的成功至关重要。
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引用次数: 4
Malaria Surveillance - United States, 2018. 疟疾监测-美国,2018。
IF 24.9 1区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-09-02 DOI: 10.15585/mmwr.ss7108a1
Kimberly E Mace, Naomi W Lucchi, Kathrine R Tan
<p><strong>Problem/condition: </strong>Malaria in humans is caused by intraerythrocytic protozoa of the genus Plasmodium. These parasites are transmitted by the bite of an infective female Anopheles species mosquito. Most malaria infections in the United States and its territories occur among persons who have traveled to regions with ongoing malaria transmission. However, among persons who have not traveled out of the country, malaria is occasionally acquired through exposure to infected blood or tissues, congenital transmission, nosocomial exposure, or local mosquitoborne transmission. Malaria surveillance in the United States and its territories provides information on its occurrence (e.g., temporal, geographic, and demographic), guides prevention and treatment recommendations for travelers and patients, and facilitates rapid transmission control measures if locally acquired cases are identified.</p><p><strong>Period covered: </strong>This report summarizes confirmed malaria cases in persons with onset of illness in 2018 and trends in previous years.</p><p><strong>Description of system: </strong>Malaria cases diagnosed by blood smear microscopy, polymerase chain reaction, or rapid diagnostic tests are reported to local and state health departments through electronic laboratory reports or by health care providers or laboratory staff members directly reporting to CDC or health departments. Case investigations are conducted by local and state health departments, and reports are transmitted to CDC through the National Malaria Surveillance System (NMSS), the National Notifiable Diseases Surveillance System (NNDSS), or direct CDC clinical consultations. CDC reference laboratories provide diagnostic assistance and conduct antimalarial drug resistance marker testing on blood specimens submitted by health care providers or local or state health departments. This report summarizes data from the integration of all cases from NMSS and NNDSS, CDC clinical consultations, and CDC reference laboratory reports.</p><p><strong>Results: </strong>CDC received reports of 1,823 confirmed malaria cases with onset of symptoms in 2018, including one cryptic case and one case acquired through a bone marrow transplant. The number of cases reported in 2018 is 15.6% fewer than in 2017. The number of cases diagnosed in the United States and its territories has been increasing since the mid-1970s; the number of cases reported in 2017 was the highest since 1972. Of the cases in 2018, a total of 1,519 (85.0%) were imported cases that originated from Africa; 1,061 (69.9%) of the cases from Africa were from West Africa, a similar proportion to what was observed in 2017. Among all cases, P. falciparum accounted for most infections (1,273 [69.8%]), followed by P. vivax (173 [9.5%]), P. ovale (95 [5.2%]), and P. malariae (48 [2.6%]). For the first time since 2008, an imported case of P. knowlesi was identified in the United States and its territories. Infections by two or more speci
问题/状况:人类疟疾是由疟原虫属红细胞内原生动物引起的。这些寄生虫通过受感染的雌性按蚊叮咬传播。在美国及其领土上,大多数疟疾感染发生在前往疟疾持续传播地区的人群中。然而,在没有出国旅行的人中,疟疾偶尔会通过接触受感染的血液或组织、先天性传播、医院接触或当地蚊子传播而获得。美国及其领土上的疟疾监测提供有关其发生情况的信息(例如,时间、地理和人口统计),指导旅行者和患者的预防和治疗建议,并在确定当地感染病例时促进快速传播控制措施。所涉期间:本报告总结了2018年发病人群中确诊的疟疾病例以及前几年的趋势。系统描述:通过血液涂片镜检、聚合酶链反应或快速诊断检测诊断的疟疾病例通过电子实验室报告报告给地方和州卫生部门,或由卫生保健提供者或实验室工作人员直接报告给疾病预防控制中心或卫生部门。病例调查由地方和州卫生部门进行,报告通过国家疟疾监测系统(NMSS)、国家法定疾病监测系统(NNDSS)或疾病预防控制中心的直接临床咨询传递给疾病预防控制中心。疾病预防控制中心参考实验室提供诊断协助,并对卫生保健提供者或地方或州卫生部门提交的血液标本进行抗疟疾耐药性标记物检测。本报告总结了来自NMSS和NNDSS的所有病例、CDC临床咨询和CDC参考实验室报告的综合数据。结果:2018年,美国疾病预防控制中心共收到1823例出现症状的疟疾确诊病例报告,其中隐匿病例1例,骨髓移植病例1例。2018年报告的病例数比2017年减少了15.6%。自20世纪70年代中期以来,美国及其领土上确诊的病例数量一直在增加;2017年报告的病例数是1972年以来的最高水平。2018年,非洲输入性病例1519例(85.0%);来自非洲的病例中有1061例(69.9%)来自西非,与2017年观察到的比例相似。其中,恶性疟原虫感染人数最多,为1273例(69.8%),其次为间日疟原虫173例(9.5%)、卵形疟原虫95例(5.2%)、疟疾疟原虫48例(2.6%)。自2008年以来,美国及其领土首次发现了一例输入性诺氏疟原虫病例。两种或两种以上疟疾感染占17例(解释:疟疾输入反映了全球进出疟疾流行地区的总体趋势,2018年输入病例比2017年减少15.6%。在输入性病例中,59.3%是来自西非的人员。在美国平民中,探亲访友是最常见的旅行原因(77.1%)。公共卫生行动:美国居民预防疟疾的最佳方法是在前往疟疾流行的国家旅行之前、期间和之后服用化学预防药物。在美国旅行者中遵守建议的疟疾预防策略将减少输入病例的数量。据报道,不坚持服药的原因包括离开疟疾流行地区后过早停止服药,忘记服药,以及出现副作用。卫生保健提供者可使旅行者了解疟疾带来的风险,并纳入教育,以激励他们坚持化学预防。如果不能根据患者的年龄、妊娠状况、病史、可能感染疟疾的国家以及以前使用过抗疟药物进行及时诊断和治疗,疟疾感染可能是致命的。应根据经常更新的疾病预防控制中心指南确定用于化学预防和治疗的抗疟药物使用。2019年4月,静脉注射青蒿琥酯(IV)成为美国及其领土治疗严重疟疾的一线药物。青蒿琥酯于2020年获得美国食品和药物管理局(FDA)的批准,并可从美国主要药品分销商(https://amivas.com)处获得(注射用青蒿琥酯)。在当地储存静脉注射青蒿琥酯可以在确诊后立即对严重疟疾进行治疗,并为患者提供完全康复和无后遗症的最佳机会。 随着商业化静脉注射青蒿琥酯现已上市,CDC将于2022年9月30日根据一项试验性新药方案停止分发未经fda批准的静脉注射青蒿琥酯。预防疟疾的详细建议可在https://www.cdc.gov/malaria/travelers/drugs.html上查阅。疟疾诊断和治疗建议也可在https://www.cdc.gov/malaria/diagnosis_treatment上获得。寻求传染病紧急咨询并在疟疾诊断和治疗方面需要额外援助的保健提供者可在上午9时至下午5时拨打疟疾热线。东部时间周一至周五,电话:770-488-7788或855-856-4713,非工作时间紧急查询电话:770-488-7100。提交疟疾病例报告的人(护理提供者、实验室以及州和地方公共卫生官员)应提供完整的信息,因为不完整的报告会影响病例调查和预防未来感染和检查疟疾病例趋势的公共卫生努力。抗疟药物耐药性标记的分子监测使疾病预防控制中心能够在国内和全球范围内跟踪、指导治疗和管理疟疾寄生虫的耐药性。需要更大比例的国内疟疾病例标本,以提高抗疟药耐药性分析的完整性;因此,疾病预防控制中心要求在美国及其领土上诊断出的任何疟疾病例都要提交血液样本。
{"title":"Malaria Surveillance - United States, 2018.","authors":"Kimberly E Mace,&nbsp;Naomi W Lucchi,&nbsp;Kathrine R Tan","doi":"10.15585/mmwr.ss7108a1","DOIUrl":"https://doi.org/10.15585/mmwr.ss7108a1","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Problem/condition: &lt;/strong&gt;Malaria in humans is caused by intraerythrocytic protozoa of the genus Plasmodium. These parasites are transmitted by the bite of an infective female Anopheles species mosquito. Most malaria infections in the United States and its territories occur among persons who have traveled to regions with ongoing malaria transmission. However, among persons who have not traveled out of the country, malaria is occasionally acquired through exposure to infected blood or tissues, congenital transmission, nosocomial exposure, or local mosquitoborne transmission. Malaria surveillance in the United States and its territories provides information on its occurrence (e.g., temporal, geographic, and demographic), guides prevention and treatment recommendations for travelers and patients, and facilitates rapid transmission control measures if locally acquired cases are identified.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Period covered: &lt;/strong&gt;This report summarizes confirmed malaria cases in persons with onset of illness in 2018 and trends in previous years.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Description of system: &lt;/strong&gt;Malaria cases diagnosed by blood smear microscopy, polymerase chain reaction, or rapid diagnostic tests are reported to local and state health departments through electronic laboratory reports or by health care providers or laboratory staff members directly reporting to CDC or health departments. Case investigations are conducted by local and state health departments, and reports are transmitted to CDC through the National Malaria Surveillance System (NMSS), the National Notifiable Diseases Surveillance System (NNDSS), or direct CDC clinical consultations. CDC reference laboratories provide diagnostic assistance and conduct antimalarial drug resistance marker testing on blood specimens submitted by health care providers or local or state health departments. This report summarizes data from the integration of all cases from NMSS and NNDSS, CDC clinical consultations, and CDC reference laboratory reports.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;CDC received reports of 1,823 confirmed malaria cases with onset of symptoms in 2018, including one cryptic case and one case acquired through a bone marrow transplant. The number of cases reported in 2018 is 15.6% fewer than in 2017. The number of cases diagnosed in the United States and its territories has been increasing since the mid-1970s; the number of cases reported in 2017 was the highest since 1972. Of the cases in 2018, a total of 1,519 (85.0%) were imported cases that originated from Africa; 1,061 (69.9%) of the cases from Africa were from West Africa, a similar proportion to what was observed in 2017. Among all cases, P. falciparum accounted for most infections (1,273 [69.8%]), followed by P. vivax (173 [9.5%]), P. ovale (95 [5.2%]), and P. malariae (48 [2.6%]). For the first time since 2008, an imported case of P. knowlesi was identified in the United States and its territories. Infections by two or more speci","PeriodicalId":48549,"journal":{"name":"Mmwr Surveillance Summaries","volume":"71 8","pages":"1-35"},"PeriodicalIF":24.9,"publicationDate":"2022-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470224/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40336731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 16
Surveillance for Coccidioidomycosis, Histoplasmosis, and Blastomycosis - United States, 2019. 球虫菌病、组织浆菌病和芽生菌病的监测-美国,2019。
IF 24.9 1区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-08-19 DOI: 10.15585/mmwr.ss7107a1
Dallas J Smith, Samantha L Williams, Kaitlin M Benedict, Brendan R Jackson, Mitsuru Toda
<p><strong>Problem/condition: </strong>Coccidioidomycosis, histoplasmosis, and blastomycosis are underdiagnosed fungal diseases that often mimic bacterial or viral pneumonia and can cause disseminated disease and death. These diseases are caused by inhalation of fungal spores that have distinct geographic niches in the environment (e.g., soil or dust), and distribution is highly susceptible to climate changes such as expanding arid regions for coccidioidomycosis, the northward expansion of histoplasmosis, and areas like New York reporting cases of blastomycosis previously thought to be nonendemic. The national incidence of coccidioidomycosis, histoplasmosis, and blastomycosis is poorly characterized.</p><p><strong>Reporting period: </strong>2019.</p><p><strong>Description of system: </strong>The National Notifiable Diseases Surveillance System (NNDSS) tracks cases of coccidioidomycosis, a nationally notifiable condition reported to CDC by 26 states and the District of Columbia. Neither histoplasmosis nor blastomycosis is a nationally notifiable condition; however, histoplasmosis is voluntarily reported in 13 states and blastomycosis in five states. Health departments classify cases based on the definitions established by the Council of State and Territorial Epidemiologists.</p><p><strong>Results: </strong>In 2019, a total of 20,061 confirmed coccidioidomycosis, 1,124 confirmed and probable histoplasmosis, and 240 confirmed and probable blastomycosis cases were reported to CDC. Arizona and California reported 97% of coccidioidomycosis cases, and Minnesota and Wisconsin reported 75% of blastomycosis cases. Illinois reported the greatest percentage (26%) of histoplasmosis cases. All three diseases were more common among males, and the proportion for blastomycosis (70%) was substantially higher than for histoplasmosis (56%) or coccidioidomycosis (52%). Coccidioidomycosis incidence was approximately four times higher for non-Hispanic American Indian or Alaska Native (AI/AN) persons (17.3 per 100,000 population) and almost three times higher for Hispanic or Latino persons (11.2) compared with non-Hispanic White (White) persons (4.1). Histoplasmosis incidence was similar across racial and ethnic categories (range: 0.9-1.3). Blastomycosis incidence was approximately six times as high among AI/AN persons (4.5) and approximately twice as high among non-Hispanic Asian and Native Hawaiian or other Pacific Islander persons (1.6) compared with White persons (0.7). More than one half of histoplasmosis (54%) and blastomycosis (65%) patients were hospitalized, and 5% of histoplasmosis and 9% of blastomycosis patients died. States in which coccidioidomycosis is not known to be endemic had more cases in spring (March, April, and May) than during other seasons, whereas the number of cases peaked slightly in autumn (September, October, and November) for histoplasmosis and in winter (December, January, and February) for blastomycosis.</p><p><strong>Interpretation: </s
问题/状况:球孢子菌病、组织胞浆菌病和芽生菌病是未被诊断的真菌疾病,通常类似细菌性或病毒性肺炎,可引起弥散性疾病和死亡。这些疾病是由吸入真菌孢子引起的,这些真菌孢子在环境中具有不同的地理生态位(例如土壤或灰尘),其分布极易受到气候变化的影响,例如球虫菌病在干旱地区的扩大,组织浆菌病的向北扩展,以及像纽约这样的地区报告了以前被认为是非地方性的孢子菌病病例。球孢子菌病、组织浆菌病和芽孢菌病的全国发病率特征不明显。报告期间:2019年。系统描述:国家法定疾病监测系统(NNDSS)跟踪球孢子菌病病例,这是由26个州和哥伦比亚特区向疾病预防控制中心报告的一种全国性法定疾病。组织胞浆菌病和芽生菌病都不是国家通报的疾病;然而,13个州报告了组织胞浆菌病,5个州报告了芽生菌病。卫生部门根据国家和地区流行病学家委员会确定的定义对病例进行分类。结果:2019年共向疾病预防控制中心报告球虫菌病确诊病例20,061例,组织浆菌病确诊和疑似病例1,124例,囊胚菌病确诊和疑似病例240例。亚利桑那州和加利福尼亚州报告了97%的球孢子菌病病例,明尼苏达州和威斯康星州报告了75%的芽孢菌病病例。伊利诺伊州报告的组织胞浆菌病病例比例最高(26%)。这三种疾病在男性中更为常见,芽孢菌病的比例(70%)大大高于组织浆菌病(56%)或球孢子菌病(52%)。与非西班牙裔美国印第安人或阿拉斯加原住民(AI/AN)相比,非西班牙裔美国印第安人或阿拉斯加原住民(AI/AN)的球虫病发病率大约高出4倍(每10万人17.3人),西班牙裔或拉丁裔人(11.2人)的球虫病发病率几乎是非西班牙裔白人(4.1人)的3倍。组织胞浆菌病的发病率在种族和民族类别中相似(范围:0.9-1.3)。与白人(0.7)相比,AI/AN人群的芽孢菌病发病率大约是白人的6倍(4.5),非西班牙裔亚洲人和夏威夷原住民或其他太平洋岛民(1.6)的发病率大约是白人的2倍(0.7)。超过一半的组织胞浆菌病(54%)和芽生菌病(65%)患者住院,5%的组织胞浆菌病和9%的芽生菌病患者死亡。在球孢子菌病未流行的州,春季(3月、4月和5月)的病例数比其他季节多,而组织胞浆菌病的病例数在秋季(9月、10月和11月)和芽孢菌病的病例数在冬季(12月、1月和2月)略有高峰。解释:球虫菌病、组织浆菌病和芽生菌病是发生在美国地理生态位的疾病。这些疾病会导致严重的疾病,2019年报告的球孢子菌病病例约为2万例。虽然组织胞浆菌病和芽生菌病的报告病例少得多,但监测却有限得多,而且很可能存在诊断不足的情况,高住院率和高死亡率就是明证。这表明,症状较轻的人可能不会寻求医疗评估,症状会自行消退,或者疾病被误诊为其他更常见的呼吸系统疾病。公共卫生行动:有必要改进监测,以更好地确定球孢子菌病的严重程度,并改进组织浆菌病和芽孢菌病的检测。这些发现可能指导改进检测实践,使真菌疾病能够及时诊断和治疗。临床医生和卫生保健专业人员应在社区获得性肺炎或其他下呼吸道急性感染患者中考虑球虫菌病、组织浆菌病和芽生菌病,这些患者居住或曾到过已知环境中存在致病真菌的地区。适合文化的量身定制的教育信息可能有助于改善诊断和治疗。对这三种疾病的公共卫生应对受到阻碍,因为从国家常规监测中收集的信息不包括风险人群和接触源的数据。更广泛的监测,包括扩展到其他州,以及关于潜在暴露和相关宿主因素的更详细信息,可以描述流行趋势、危险人群和疾病预防策略。
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引用次数: 9
Surveillance for Violent Deaths - National Violent Death Reporting System, 42 States, the District of Columbia, and Puerto Rico, 2019. 暴力死亡监测-国家暴力死亡报告系统,42个州,哥伦比亚特区和波多黎各,2019年。
IF 24.9 1区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-05-20 DOI: 10.15585/mmwr.ss7106a1
Rebecca F Wilson, Grace Liu, Bridget H Lyons, Emiko Petrosky, Dominque D Harrison, Carter J Betz, Janet M Blair
<p><strong>Problem/condition: </strong>In 2019, approximately 67,000 persons died of violence-related injuries in the United States. This report summarizes data from CDC's National Violent Death Reporting System (NVDRS) on violent deaths that occurred in 42 states, the District of Columbia, and Puerto Rico in 2019. Results are reported by sex, age group, race and ethnicity, method of injury, type of location where the injury occurred, circumstances of injury, and other selected characteristics.</p><p><strong>Period covered: </strong>2019.</p><p><strong>Description of system: </strong>NVDRS collects data regarding violent deaths obtained from death certificates, coroner and medical examiner records, and law enforcement reports. This report includes data collected for violent deaths that occurred in 2019. Data were collected from 39 states with statewide data (Alabama, Alaska, Arizona, Colorado, Connecticut, Delaware, Georgia, Hawaii, Indiana, Iowa, Kansas, Kentucky, Louisiana, Maine, Maryland, Massachusetts, Michigan, Minnesota, Missouri, Montana, Nebraska, Nevada, New Hampshire, New Jersey, New Mexico, North Carolina, North Dakota, Ohio, Oklahoma, Oregon, Rhode Island, South Carolina, Utah, Vermont, Virginia, Washington, West Virginia, Wisconsin, and Wyoming), three states with data from counties representing a subset of their population (30 California counties, representing 57% of its population, and 47 Illinois counties and 40 Pennsylvania counties, representing at least 80% of their populations), the District of Columbia, and Puerto Rico. NVDRS collates information for each violent death and links deaths that are related (e.g., multiple homicides, homicide followed by suicide, or multiple suicides) into a single incident.</p><p><strong>Results: </strong>For 2019, NVDRS collected information on 50,374 fatal incidents involving 51,627 deaths that occurred in 42 states (39 states collecting statewide data, 30 California counties, 47 Illinois counties, and 40 Pennsylvania counties), and the District of Columbia. In addition, information was collected for 831 fatal incidents involving 897 deaths in Puerto Rico. Data for Puerto Rico were analyzed separately. Of the 51,627 deaths, the majority (64.1%) were suicides, followed by homicides (25.1%), deaths of undetermined intent (8.7%), legal intervention deaths (1.4%) (i.e., deaths caused by law enforcement and other persons with legal authority to use deadly force acting in the line of duty, excluding legal executions), and unintentional firearm deaths (<1.0%). The term "legal intervention" is a classification incorporated into the International Classification of Diseases, Tenth Revision, and does not denote the lawfulness or legality of the circumstances surrounding a death caused by law enforcement. Demographic patterns and circumstances varied by manner of death. The suicide rate was higher for males than for females. Across all age groups, the suicide rate was highest among adults aged 45-54 years
问题/状况:2019年,美国约有6.7万人死于与暴力有关的伤害。本报告总结了疾病预防控制中心国家暴力死亡报告系统(NVDRS)关于2019年发生在42个州、哥伦比亚特区和波多黎各的暴力死亡的数据。结果按性别、年龄组、种族和民族、受伤方法、受伤发生的位置类型、受伤情况和其他选定的特征报告。涵盖时间:2019年。系统描述:NVDRS从死亡证明、验尸官和法医记录以及执法报告中收集有关暴力死亡的数据。本报告包括收集的2019年发生的暴力死亡数据。数据收集自39个州的全州数据(阿拉巴马州、阿拉斯加州、亚利桑那州、科罗拉多州、康涅狄格州、特拉华州、佐治亚州、夏威夷州、印第安纳州、爱荷华州、堪萨斯州、肯塔基州、路易斯安那州、缅因州、马里兰州、马萨诸塞州、密歇根州、明尼苏达州、密苏里州、蒙大拿州、内布拉斯加州、内华达州、新罕布什尔州、新泽西州、新墨西哥州、北卡罗来纳州、北达科他州、俄亥俄州、俄克拉荷马州、俄勒冈州、罗德岛州、南卡罗来纳州、犹他州、佛蒙特州、弗吉尼亚州、华盛顿州、西弗吉尼亚州、威斯康星州和怀俄明州)。三个州的数据来自代表其人口子集的县(加利福尼亚州的30个县,占其人口的57%,伊利诺伊州的47个县和宾夕法尼亚州的40个县,至少占其人口的80%),哥伦比亚特区和波多黎各。NVDRS对每一起暴力死亡事件的信息进行整理,并将相关的死亡事件(例如,多次杀人、杀人后自杀或多次自杀)联系到一起。结果:2019年,NVDRS收集了42个州和哥伦比亚特区发生的50,374起致命事件的信息,涉及51,627人死亡(39个州收集全州数据,30个加利福尼亚州,47个伊利诺伊州和40个宾夕法尼亚州县)。此外,还收集了波多黎各831起致命事件的资料,涉及897人死亡。波多黎各的数据被单独分析。在51,627例死亡中,大多数(64.1%)是自杀,其次是他杀(25.1%)、不明意图死亡(8.7%)、法律干预死亡(1.4%)(即由执法人员和其他依法有权使用致命武力执行任务的人造成的死亡,不包括合法处决)和非故意枪支死亡(解释:本报告提供了NVDRS关于2019年发生的暴力死亡的详细数据摘要。自杀率在AI/AN和白人男性中最高,而杀人率在黑人男性中最高。精神健康问题、亲密伴侣问题、人际冲突和急性生活压力是多种类型暴力死亡的主要情况。公共卫生行动:暴力是可以预防的,数据可以指导公共卫生行动。NVDRS数据用于监测与暴力有关的致命伤害的发生,并协助公共卫生当局制定、实施和评估减少和预防暴力死亡的方案、政策和做法。例如,新罕布什尔州暴力死亡报告系统(VDRS)、印第安纳州VDRS和科罗拉多州VDRS使用他们的VDRS数据来指导自杀预防工作,并生成报告,强调需要额外关注的地方。在新罕布什尔州,VDRS数据已被用于监测2014-2018年自杀率的上升,并指导全州范围内的合作预防工作。印第安纳州VDRS利用当地数据证明了黑人在自杀和其他相关心理健康问题方面的差异,并强调需要提高对自杀的认识和具有文化能力的心理保健。科罗拉多州VDRS进行了地理空间和人口统计分析,将当地VDRS数据与现有的自杀预防工作和资源相结合,以确定自杀率高的地区和自杀风险高的人口。同样,参与NVDRS的州也使用他们的VDRS数据来检查该州的凶杀案。例如,在北卡罗来纳州,AI/AN和黑人的杀人率大约是全州杀人率的2.5倍,北卡罗来纳州VDRS计划旨在与该州历史上的黑人学院和大学合作,培训研究人员使用VDRS数据来解决其直接社区及其周围的卫生公平问题。
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引用次数: 21
Assisted Reproductive Technology Surveillance - United States, 2018. 辅助生殖技术监测-美国,2018年。
IF 24.9 1区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-02-18 DOI: 10.15585/mmwr.ss7104a1
Saswati Sunderam, Dmitry M Kissin, Yujia Zhang, Amy Jewett, Sheree L Boulet, Lee Warner, Charlan D Kroelinger, Wanda D Barfield

Problem/condition: Since the first U.S. infant conceived with assisted reproductive technology (ART) was born in 1981, both the use of ART and the number of fertility clinics providing ART services have increased steadily in the United States. ART includes fertility treatments in which eggs or embryos are handled in the laboratory (i.e., in vitro fertilization [IVF] and related procedures). Although the majority of infants conceived through ART are singletons, women who undergo ART procedures are more likely than women who conceive naturally to have multiple births because multiple embryos might be transferred. Multiple births can pose substantial risks for both mothers and infants, including obstetric complications, preterm birth (<37 weeks), and low birthweight (<2,500 g). This report provides state-specific information for the United States (including the District of Columbia and Puerto Rico) on ART procedures performed in 2018 and compares birth outcomes that occurred in 2018 (resulting from ART procedures performed in 2017 and 2018) with outcomes for all infants born in the United States in 2018.

Period covered: 2018.

Description of system: In 1995, CDC began collecting data on ART procedures performed in fertility clinics in the United States as mandated by the Fertility Clinic Success Rate and Certification Act of 1992 (Public Law 102-493 [October 24, 1992]). Data are collected through the National ART Surveillance System (NASS), a web-based data collection system developed by CDC. This report includes data from the 50 U.S. states, the District of Columbia, and Puerto Rico.

Results: In 2018, a total of 203,119 ART procedures (range: 196 in Alaska to 26,028 in California) were performed in 456 U.S. fertility clinics and reported to CDC. These procedures resulted in 73,831 live-birth deliveries (range: 76 in Puerto Rico and Wyoming to 9,666 in California) and 81,478 infants born (range: 84 in Wyoming to 10,620 in California). Nationally, among women aged 15-44 years, the rate of ART procedures performed was 3,135 per 1 million women. ART use exceeded 1.5 times the national rate in seven states (Connecticut, Illinois, Maryland, Massachusetts, New Jersey, New York, and Rhode Island) and the District of Columbia. ART use rates exceeded the national rate in an additional seven states (California, Delaware, Hawaii, New Hampshire, Utah, Vermont, and Virginia). Nationally, among all ART transfer procedures, the average number of embryos transferred was similar across age groups (1.3 among women aged <35 years, 1.3 among women aged 35-37 years, and 1.4 among women aged >37 years). The national single-embryo transfer (SET) rate among all embryo-transfer procedures was 74.1% among women aged <35 years (range: 28.2% in Puerto Rico to 89.5% in Delaware), 72.8% among women aged 35-37 years (range: 30.6% in Puerto Rico to 93.7% in Delaware), and 66.4% among women aged

问题/状况:自1981年美国第一个通过辅助生殖技术(ART)受孕的婴儿出生以来,美国ART的使用和提供ART服务的生育诊所的数量都在稳步增加。抗逆转录病毒技术包括在实验室处理卵子或胚胎的生育治疗(即体外受精[IVF]和相关程序)。虽然大多数通过抗逆转录病毒技术怀孕的婴儿是单胎,但接受抗逆转录病毒技术的妇女比自然怀孕的妇女更有可能生多胎,因为多个胚胎可能被转移。多胎可对母亲和婴儿构成重大风险,包括产科并发症、早产(涵盖期间:2018年)。系统描述:1995年,CDC根据1992年生育诊所成功率和认证法案(Public Law 102-493 [October 24, 1992])的规定,开始收集美国生育诊所进行ART手术的数据。数据是通过国家抗逆转录病毒药物监测系统(NASS)收集的,这是一个由疾病预防控制中心开发的基于网络的数据收集系统。这份报告包括来自美国50个州、哥伦比亚特区和波多黎各的数据。结果:2018年,美国456家生育诊所共进行了203,119例ART手术(范围:阿拉斯加196例,加州26,028例),并向疾病预防控制中心报告。这些程序导致73,831例活产分娩(范围:波多黎各和怀俄明州的76例到加利福尼亚州的9,666例)和81,478例婴儿出生(范围:怀俄明州的84例到加利福尼亚州的10,620例)。在全国范围内,年龄在15-44岁的妇女中,接受抗逆转录病毒治疗的比率为每100万妇女3135例。在七个州(康涅狄格州、伊利诺伊州、马里兰州、马萨诸塞州、新泽西州、纽约州和罗德岛州)和哥伦比亚特区,抗逆转录病毒治疗的使用率超过了全国使用率的1.5倍。另外七个州(加利福尼亚州、特拉华州、夏威夷、新罕布什尔州、犹他州、佛蒙特州和弗吉尼亚州)的抗逆转录病毒治疗使用率超过了全国水平。在全国范围内,在所有抗逆转录病毒技术移植程序中,移植胚胎的平均数量在各年龄组中相似(37岁妇女中有1.3个)。37岁女性的全国单胚胎移植(SET)率为74.1%(范围:波多黎各27.1%至特拉华州85.3%)。2018年,ART在2017年和2018年进行的手术中占美国出生婴儿总数的2.0%(范围:波多黎各0.4%至马萨诸塞州5.1%)。约78.6%的人工受孕婴儿是单胎婴儿。总的来说,抗逆转录病毒治疗导致了12.5%的多胞胎出生,包括12.5%的双胞胎出生和13.3%的三胞胎和高序胞胎出生。在所有人工受精多胞胎中,双胞胎约占97.1%(16,001例中有15,532例)。接受抗逆转录病毒治疗的婴儿中多胞胎的比例(21.4%)高于出生人口中所有婴儿的比例(3.3%)。大约20.7%(74,926例中有15,532例)的人工受精婴儿是双胞胎,0.6%(74,926例中有469例)是三胞胎和高倍数。在全国范围内,接受抗逆转录病毒治疗的婴儿占所有低出生体重婴儿的4.2%(解释:尽管单胎婴儿占接受抗逆转录病毒治疗的婴儿的大多数,但接受抗逆转录病毒治疗的多胎婴儿在各州和全国范围内存在很大差异,占美国出生的所有双胞胎、三胞胎和高序多胎婴儿的12%以上。由于多胎分娩的早产率高于单胎分娩,抗逆转录病毒治疗对不良分娩结果的影响仍然值得注意。虽然所有年龄组的SET率都有所增加,但各州和地区之间的SET率仍然存在差异,这可能反映了生育诊所之间胚胎移植实践的差异,并可能部分解释了各州和地区之间多胎出生率的差异。公共卫生行动:在临床上适当的情况下,减少胚胎移植数量和增加使用人工授精技术,有助于减少多胎分娩和对母婴造成的相关不良健康后果。虽然多胎妊娠对母亲的风险包括更高的剖腹产率、妊娠期高血压和妊娠期糖尿病,但多胎妊娠的婴儿出现许多不良后遗症(如早产、出生缺陷和发育障碍)的风险增加。通过整合现有的母婴健康监测系统和NASS提供的数据,对抗逆转录病毒治疗婴儿进行长期随访,可能有助于在人群基础上监测不良后果。
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引用次数: 32
Surveillance for Violent Deaths - National Violent Death Reporting System, 39 States, the District of Columbia, and Puerto Rico, 2018. 暴力死亡监测--全国暴力死亡报告系统,39个州、哥伦比亚特区和波多黎各,2018年。
IF 37.3 1区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-01-28 DOI: 10.15585/mmwr.ss7103a1
Kameron J Sheats, Rebecca F Wilson, Bridget H Lyons, Shane P D Jack, Carter J Betz, Katherine A Fowler

Problem/condition: In 2018, approximately 68,000 persons died of violence-related injuries in the United States. This report summarizes data from CDC's National Violent Death Reporting System (NVDRS) on violent deaths that occurred in 39 states the District of Columbia, and Puerto Rico in 2018. Results are reported by sex, age group, race and ethnicity, method of injury, type of location where the injury occurred, circumstances of injury, and other selected characteristics.

Period covered: 2018.

Description of system: NVDRS collects data regarding violent deaths obtained from death certificates, coroner and medical examiner reports, and law enforcement reports. This report includes data collected for violent deaths that occurred in 2018. Data were collected from 36 states with statewide data (Alabama, Alaska, Arizona, Colorado, Connecticut, Delaware, Georgia, Indiana, Iowa, Kansas, Kentucky, Louisiana, Maine, Maryland, Massachusetts, Michigan, Minnesota, Missouri, Nebraska, Nevada, New Hampshire, New Jersey, New Mexico, New York, North Carolina, Ohio, Oklahoma, Oregon, Rhode Island, South Carolina, Utah, Vermont, Virginia, Washington, West Virginia, and Wisconsin), three states with data from counties representing a subset of their population (21 California counties, 28 Illinois counties, and 39 Pennsylvania counties), the District of Columbia, and Puerto Rico. NVDRS collates information for each death and links deaths that are related (e.g., multiple homicides, homicide followed by suicide, or multiple suicides) into a single incident.

Results: For 2018, NVDRS collected information on 52,773 fatal incidents involving 54,170 deaths that occurred in 39 states and the District of Columbia. In addition, information was collected on 880 fatal incidents involving 975 deaths in Puerto Rico. Data for Puerto Rico were analyzed separately. Of the 54,170 deaths, the majority (64.1%) were suicides, followed by homicides (24.8%), deaths of undetermined intent (9.0%), legal intervention deaths (1.4%) (i.e., deaths caused by law enforcement and other persons with legal authority to use deadly force acting in the line of duty, excluding legal executions), and unintentional firearm deaths (<1.0%). (The term "legal intervention" is a classification incorporated into the International Classification of Diseases, Tenth Revision, and does not denote the lawfulness or legality of the circumstances surrounding a death caused by law enforcement.) Demographic patterns and circumstances varied by manner of death. The suicide rate was higher among males than among females and was highest among adults aged 35-64 years and non-Hispanic American Indian or Alaska Native (AI/AN) and non-Hispanic White persons. The most common method of injury for suicide was a firearm among males and hanging, strangulation, or suffocation among females. Suicide was most often preceded by a mental health, i

问题/条件:2018 年,美国约有 68,000 人死于与暴力有关的伤害。本报告总结了美国疾病预防控制中心国家暴力死亡报告系统(NVDRS)提供的数据,涉及 2018 年在 39 个州、哥伦比亚特区和波多黎各发生的暴力死亡事件。结果按性别、年龄组、种族和民族、伤害方式、伤害发生地类型、伤害情况以及其他选定特征进行了报告。覆盖时期:2018年。系统描述:NVDRS:NVDRS 从死亡证明、验尸官和法医报告以及执法报告中收集有关暴力死亡的数据。本报告包括收集到的 2018 年发生的暴力死亡数据。数据收集自 36 个拥有全州数据的州(阿拉巴马州、阿拉斯加州、亚利桑那州、科罗拉多州、康涅狄格州、特拉华州、佐治亚州、印第安纳州、爱荷华州、堪萨斯州、肯塔基州、路易斯安那州、缅因州、马里兰州、马萨诸塞州、密歇根州、明尼苏达州、密苏里州、内布拉斯加州、内华达州、新罕布什尔州、新泽西州、新墨西哥州、纽约州、北卡罗来纳州、俄亥俄州、俄克拉荷马州、俄勒冈州、罗得岛州、南卡罗来纳州、犹他州、佛蒙特州、弗吉尼亚州、华盛顿州、西弗吉尼亚州和威斯康星州)、三个州(数据来自代表其人口子集的县(加利福尼亚州 21 个县、伊利诺伊州 28 个县和宾夕法尼亚州 39 个县))、哥伦比亚特区和波多黎各。NVDRS 整理了每例死亡的信息,并将相关的死亡(如多起凶杀、凶杀后自杀或多起自杀)联系到一起事件中:2018 年,NVDRS 收集了发生在 39 个州和哥伦比亚特区的 52,773 起死亡事件的信息,涉及 54,170 例死亡。此外,还收集了波多黎各 880 起死亡事件的信息,涉及 975 人死亡。波多黎各的数据单独进行了分析。在 54,170 例死亡中,大多数(64.1%)是自杀,其次是他杀(24.8%)、意图不明的死亡(9.0%)、合法干预死亡(1.4%)(即执法人员和其他有合法权力使用致命武力的人员在执行公务时造成的死亡,不包括合法处决),以及非故意的枪支致死(解释:这是指在执行公务时使用致命武力造成的死亡):本报告详细总结了 NVDRS 提供的 2018 年发生的暴力死亡数据。非西班牙裔美国原住民和非西班牙裔白人男性的自杀率最高,非西班牙裔黑人男性的凶杀率最高。精神健康问题、亲密伴侣问题、人际冲突和严重的生活压力是多种类型暴力死亡的主要情况。杀人嫌疑犯的情况因年龄组而异,包括曾与执法部门接触和参与由其他犯罪、亲密伴侣暴力和毒品交易或药物使用引发的事件:NVDRS 数据用于监测与暴力有关的致命伤害的发生情况,并协助公共卫生部门制定、实施和评估旨在减少和预防暴力致死的计划、政策和做法。例如,亚利桑那州和威斯康星州利用州级 VDRS 数据支持各自州内的自杀预防工作。威斯康星州 VDRS 使用多年的数据(2013-2017 年)来确定重要的风险和保护因素,并随后制定了一项全面的自杀预防计划。亚利桑那州退伍军人登记系统(Arizona VDRS)与亚利桑那州 "连接倡议"(Arizona Be Connected Initiative)合作,提供亚利桑那州退伍军人自杀死亡的定制社区级数据。同样,参与 NVDRS 的各州也利用其 VDRS 数据来检查亲密伴侣暴力相关的死亡情况,以支持预防工作。例如,南卡罗来纳州 VDRS 的数据被用于检查 2017 年期间在南卡罗来纳州发生的亲密伴侣杀人案件。南卡罗来纳州 VDRS 发现,2017 年发生的所有凶杀案中有 12% 与亲密伴侣暴力有关,女性占亲密伴侣凶杀案相关受害者的 52%。这些数据已与南卡罗来纳州的家庭暴力预防合作者共享,以加强他们在减少亲密伴侣暴力相关死亡方面的努力。与2017年相比,2018年的NVDRS数据增加了四个州,为公共卫生工作提供了更全面、更可操作的暴力死亡信息,以减少暴力死亡。
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Mmwr Surveillance Summaries
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