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The effect of motor imagery on the excitability of spinal segmentary reflexes in restless legs syndrome patients 运动意象对不宁腿综合征患者脊柱节段性反射兴奋性的影响
IF 0.4 4区 医学 Q4 NEUROSCIENCES Pub Date : 2022-01-01 DOI: 10.4103/nsn.nsn_221_20
F. Yavlal, M. Kiziltan
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引用次数: 0
The role of occipital cortex hyperexcitability in visual snow syndrome 枕皮质高兴奋性在视觉雪综合征中的作用
IF 0.4 4区 医学 Q4 NEUROSCIENCES Pub Date : 2022-01-01 DOI: 10.4103/nsn.nsn_193_21
I. Unal‐Cevik
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引用次数: 1
The reliability and validity of the Turkish version of the fatigue assessment scale in patients with multiple sclerosis 土耳其版多发性硬化症患者疲劳评定量表的信度和效度
IF 0.4 4区 医学 Q4 NEUROSCIENCES Pub Date : 2022-01-01 DOI: 10.4103/nsn.nsn_142_21
Fatih Özden, Mehmet Ozkeskin, N. Yüceyar
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引用次数: 0
Cognitive evidence on EEG-P300 in healthy individuals with high depression scores 抑郁得分高的健康个体EEG-P300的认知证据
IF 0.4 4区 医学 Q4 NEUROSCIENCES Pub Date : 2022-01-01 DOI: 10.4103/nsn.nsn_185_21
Didem Oz, Yagmur Özbek, Ilayda Kiyi, BilgeTargitay Öztürk, I. Öztura, G. Yener
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引用次数: 0
Evaluation of brain death due to methanol intoxication 甲醇中毒致脑死亡的评估
IF 0.4 4区 医学 Q4 NEUROSCIENCES Pub Date : 2022-01-01 DOI: 10.4103/nsn.nsn_128_21
T. Mengi, Hüseyin Özkök, Ö. Öner, E. Yaka, Bilgin Cömert, A. Gökmen
Objective: Intoxication may mimic brain death and cause brain death. In the literature, brain death due to methanol intoxication is limited to case reports. In this report, patients with methanol intoxication who had findings of imminent brain death were evaluated. Materials and Methods: The study population consisted of patients with methanol intoxication treated in the adult intensive care unit (ICU) between October 2014 and October 2020. The records in the hospital automation system of patients with methanol intoxication were evaluated retrospectively. According to the outcomes, the patients were divided into two groups: survivors and patients who had imminent brain death. Results: Eighteen patients with methanol intoxication were investigated. The brainstem reflexes disappeared in seven patients who were in a coma. The imminent brain death rate of patients with methanol intoxication was 39%. Patients who had imminent brain death had lower Glasgow Coma Scale scores during ICU admission and a higher ratio of pathologic neuroimaging findings due to methanol intoxication (P < 0.05). According to the clinical criteria and ancillary tests, four patients were declared brain dead. The brain death rate of patients with methanol intoxication was 22%. One of four patients with brain death was an organ donor. The liver was transplanted from our donor. Conclusion: Treatment should be initiated immediately in cases of methanol intoxication. Patients who do not respond well to treatment should be followed closely in terms of brain death. Based on published data and our personal experience, organ donations can be performed after appropriate investigations in brain death cases due to methanol intoxication.
目的:中毒可模拟脑死亡,引起脑死亡。在文献中,甲醇中毒导致的脑死亡仅限于病例报告。在本报告中,对发现即将发生脑死亡的甲醇中毒患者进行了评估。材料和方法:研究人群包括2014年10月至2020年10月在成人重症监护室(ICU)接受治疗的甲醇中毒患者。对甲醇中毒患者在医院自动化系统中的记录进行回顾性评价。根据结果,患者被分为两组:幸存者和即将脑死亡的患者。结果:对18例甲醇中毒患者进行了调查。7名昏迷患者脑干反射消失。甲醇中毒患者的近期脑死亡率为39%。即将发生脑死亡的患者在入住ICU期间格拉斯哥昏迷量表评分较低,甲醇中毒引起的病理性神经影像学检查结果比率较高(P<0.05)。根据临床标准和辅助测试,有4名患者被宣布脑死亡。甲醇中毒患者的脑死亡率为22%。四名脑死亡患者中有一名是器官捐献者。肝脏是从我们的捐赠者那里移植的。结论:甲醇中毒应立即开始治疗。对治疗反应不佳的患者应密切关注脑死亡情况。根据已公布的数据和我们的个人经验,在对甲醇中毒导致的脑死亡病例进行适当调查后,可以进行器官捐献。
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引用次数: 0
Autologous stem cell transplantation in a patient with refractory anti-MuSK-Positive myasthenia gravis and familial mediterranean fever 自体干细胞移植治疗难治性重症肌无力合并家族性地中海热1例
IF 0.4 4区 医学 Q4 NEUROSCIENCES Pub Date : 2022-01-01 DOI: 10.4103/nsn.nsn_197_21
Berin Inan, C. Bekircan-Kurt, H. Demiroğlu, H. Göker, Sevim Erdem‐Özdamar, E. Tan
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引用次数: 1
Tremor and myoclonus is common in immune-mediated and hereditary polyneuropathies 震颤和肌阵挛在免疫介导的遗传性多神经病变中很常见
IF 0.4 4区 医学 Q4 NEUROSCIENCES Pub Date : 2022-01-01 DOI: 10.4103/nsn.nsn_99_21
D. Tezer, A. Gündüz, M. Tütüncü, M. Akalın, N. Adatepe, F. Savrun, M. Kiziltan
Objective: Our goal was to identify the frequency and types of involuntary movements in immune mediated and hereditary polyneuropathies. Methods: In this prospective study, we included all consecutive patients with immune mediated or hereditary polyneuropathy between January 2017 and November 2019. The presence and type of the involuntary movements were determined by the clinical examination and multichannel surface electromyography. Results: We identified 23 (48.9%) patients with involuntary movements among 47 patients with immune mediated or hereditary polyneuropathy in the study period. All patients with an involuntary movement had postural tremor with accompanying action and/or rest tremor. Short duration and high-amplitude myoclonus was accompanying in 18 (38.3%) patients. The demographic and clinical characteristics and features of nerve conduction studies were similar between patients with and without involuntary movements. Discussion: Tremor and myoclonus were frequent in our cohort. Postural tremor was the most frequent subtype. There was no significant relationship between myoclonus or tremor and clinical/electrophysiological features. Conclusion: For assessing movement disorders in polyneuropathies not only clinical examination, but also electrophysiological studies such as multichannel surface electromyography should be used.
目的:我们的目的是确定免疫介导和遗传性多发性神经病中非自主运动的频率和类型。方法:在这项前瞻性研究中,我们纳入了2017年1月至2019年11月期间所有连续的免疫介导或遗传性多发性神经病患者。通过临床检查和多通道表面肌电图来确定不自主运动的存在和类型。结果:在研究期间,我们在47名免疫介导或遗传性多发性神经病患者中确定了23名(48.9%)患者有不自主运动。所有不自主运动的患者都有伴随动作和/或休息的体位性震颤。18例(38.3%)患者伴有短时高振幅肌阵挛。非自主运动和非自主运动患者的神经传导研究的人口统计学和临床特征相似。讨论:震颤和肌阵挛在我们的队列中很常见。体位性震颤是最常见的亚型。肌阵挛或震颤与临床/电生理特征之间没有显著关系。结论:评估多发性神经病的运动障碍,不仅要进行临床检查,还要进行多通道表面肌电图等电生理学研究。
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引用次数: 0
The effect of risk factors on the clinical course and treatment of older patients with coronavirus disease 2019 危险因素对2019年冠状病毒病老年患者临床病程及治疗的影响
IF 0.4 4区 医学 Q4 NEUROSCIENCES Pub Date : 2022-01-01 DOI: 10.4103/nsn.nsn_114_21
U. Duzgun, A. Sonkaya, B. Öztürk, O. Sarı, E. Yurdakul, Ümit Savaşçı, D. Doğan, Ö. Karadaş
Introduction: Coronavirus disease 2019 (COVID-19) is known to have higher morbidity and mortality rates, parallel to the increased risk factors in the elderly. We aimed to define the risk factors related to mortality and morbidity in older patients hospitalized with COVID-19 disease in this study. Materials and Methods: This retrospective cross-sectional study included patients aged ≥65 years who were hospitalized with a confirmed diagnosis of COVID-19. We analyzed their demographic data, clinical findings, comorbidities, laboratory and radiologic findings, treatment protocols, and outcomes. Results: A total of 58 patients were included in the study. A total of eight (13.8%) patients died during the clinical follow-up and treatment, and 50 (86.2%) patients were discharged. The most common comorbidities among all patients were hypertension (HT) (69%) and diabetes mellitus (39.7%). The most common symptoms include fever (51.7%), cough (44.8%), and dyspnea (43.1%), and the most common neurologic findings were headache (27.6%) and impaired consciousness (27.6%). Intensive care unit admission was significantly higher among patients with comorbidities of HT, cerebrovascular disease, atrial fibrillation (AF), and chronic obstructive pulmonary disease. The rate of death was significantly higher in patients with a history of smoking, cerebrovascular disease, AF, and HT. Although there was a statistically significant positive correlation between the death rate and leukocyte, neutrophil, C-reactive protein, lactate dehydrogenase, D-dimer, interleukin-6, and procalcitonin levels, a negative correlation was observed in lymphocyte levels. Conclusion: Age-related comorbid conditions, especially HT, cerebrovascular disease, and AF, caused increased morbidity and mortality rates in older patients with COVID-19.
导言:已知2019冠状病毒病(COVID-19)具有较高的发病率和死亡率,与老年人风险因素增加平行。在本研究中,我们旨在确定与COVID-19住院老年患者死亡率和发病率相关的危险因素。材料和方法:本回顾性横断面研究纳入年龄≥65岁且确诊为COVID-19住院的患者。我们分析了他们的人口统计数据、临床表现、合并症、实验室和放射学表现、治疗方案和结果。结果:共纳入58例患者。临床随访治疗中死亡8例(13.8%),出院50例(86.2%)。所有患者中最常见的合并症是高血压(69%)和糖尿病(39.7%)。最常见的症状包括发热(51.7%)、咳嗽(44.8%)和呼吸困难(43.1%),最常见的神经系统症状是头痛(27.6%)和意识受损(27.6%)。合并HT、脑血管疾病、心房颤动(AF)和慢性阻塞性肺疾病的患者入住重症监护病房的比例明显更高。有吸烟史、脑血管疾病史、房颤史和HT史的患者死亡率明显较高。虽然死亡率与白细胞、中性粒细胞、c反应蛋白、乳酸脱氢酶、d -二聚体、白细胞介素-6、降钙素原水平呈正相关,但与淋巴细胞水平呈负相关。结论:年龄相关的合并症,尤其是HT、脑血管疾病和房颤导致老年COVID-19患者的发病率和死亡率增加。
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引用次数: 0
Could we Predict Respiratory Failure in Amyotrophic Lateral Sclerosis? 我们能否预测肌萎缩侧索硬化症患者的呼吸衰竭?
IF 0.4 4区 医学 Q4 NEUROSCIENCES Pub Date : 2022-01-01 DOI: 10.4103/nsn.nsn_210_21
C. Akkoc, S. Aykac, F. Bademki̇ran, I. Aydogdu, S. Taşbakan
Introduction: Respiratory complications are important in the prognosis of amyotrophic lateral sclerosis (ALS). The aim of this study was to determine the electrophysiological findings that may predict respiratory failure. Methods: According to the Awaji electrodiagnostic criteria, 30 patients with ALS who were diagnosed with definite or probable ALS without respiratory failure were included in the study. Nerve conduction studies, needle electromyography (EMG), and single-breath count tests were performed in all patients. In addition, the pulmonary function tests, swallowing EMG, and arterial blood gas analysis of the patients were recorded and evaluated. The patients were followed until respiratory failure developed. Results: As a result of 18 months of follow-up, 26 of 30 patients developed respiratory failure. When the contribution of the accessory respiratory muscles to the respiratory effort before the development of respiratory failure was evaluated clinically and electrophysiologically, it was observed that the most common muscles involved in the respiratory effort were sternocleidomastoid (SCM), trapezius, and rectus abdominis. Before the development of respiratory failure, the latest neurogenic EMG findings were seen in the SCM (50% cases), trapezius (20% cases), and thoracic paraspinal muscles (17% of cases), respectively. It was thought that this finding could be an important early electrophysiologic marker in predicting the development of respiratory failure in ALS cases. Conclusions: To sum up, the presence of neurogenic changes in certain muscles in needle EMG and demonstration of the contribution of certain accessory respiratory muscles in respiration can be used as an electrophysiological marker to predict the development of respiratory failure.
引言:呼吸系统并发症对肌萎缩侧索硬化症(ALS)的预后很重要。本研究的目的是确定可能预测呼吸衰竭的电生理学结果。方法:根据Awaji电诊断标准,将30名被诊断为明确或可能患有ALS但无呼吸衰竭的ALS患者纳入研究。对所有患者进行了神经传导研究、针肌电图(EMG)和单次呼吸计数测试。此外,还记录和评估了患者的肺功能测试、吞咽肌电图和动脉血气分析。对患者进行随访,直到出现呼吸衰竭。结果:经过18个月的随访,30名患者中有26人出现呼吸衰竭。当对呼吸衰竭发生前副呼吸肌对呼吸努力的贡献进行临床和电生理评估时,观察到参与呼吸努力的最常见肌肉是胸锁乳突肌(SCM)、斜方肌和腹直肌。在呼吸衰竭发展之前,最新的神经源性肌电图检查结果分别出现在SCM(50%的病例)、斜方肌(20%的病例)和胸棘旁肌(17%的病例)中。人们认为,这一发现可能是预测ALS病例呼吸衰竭发展的重要早期电生理标志。结论:总之,针肌电图中某些肌肉的神经源性变化以及某些呼吸辅助肌肉对呼吸的贡献的证明可以作为预测呼吸衰竭发展的电生理标志。
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引用次数: 0
A rare paraneoplastic finding of the breast cancer and chronic inflammatory demyelinating polyneuropathy 乳腺癌症和慢性炎性脱髓鞘多发性神经病的罕见副肿瘤发现
IF 0.4 4区 医学 Q4 NEUROSCIENCES Pub Date : 2022-01-01 DOI: 10.4103/nsn.nsn_123_21
B. Ateş, Kezban Aslan-Kara, M. Ergin, H. Bozdemir
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引用次数: 0
期刊
Neurological Sciences and Neurophysiology
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