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Comparison between home-based and supervised rehabilitation protocols after anterior cruciate ligament reconstruction: a systematic review and meta-analysis. 前交叉韧带重建后家庭康复方案与监督康复方案的比较:系统回顾和荟萃分析。
IF 4 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-09-04 DOI: 10.1530/EOR-2024-0216
Waleed D Khubzan, Khalid M Alhomayani

Purpose: This systematic review and meta-analysis assesses the comparative effectiveness of home-based and supervised rehabilitation protocols following anterior cruciate ligament reconstruction, with a focus on functional recovery and muscle strength.

Methods: Registered in PROSPERO (CRD42024585478) and following PRISMA guidelines, we searched Web of Science, PubMed, Ovid MEDLINE, and Cochrane. For the quality assessment, the Cochrane Collaboration risk of bias (RoB) tool was used. Review Manager v5.4 was used for the analysis.

Results: Twelve studies were included qualitatively, and seven quantitatively. Outcomes included subjective knee scores (Lysholm, Tegner, IKDC) and quadriceps/hamstring strength measures. Our findings indicated a 19% improvement in subjective knee scores for home-based protocols in some studies. However, for hamstring strength measures, the supervised protocol was superior (SMD = -0.48, P = 0.02).

Conclusion: Overall, home-based rehabilitation outcomes were comparable to supervised programs in functional recovery. However, supervised approaches slightly enhanced muscle strength. Supervised rehabilitation is recommended to optimize strength, especially for athletes, though further research is needed to assess its impact on return to sport.

目的:本系统综述和荟萃分析评估了前交叉韧带重建后家庭康复方案和监督康复方案的比较有效性,重点是功能恢复和肌肉力量。方法:在PROSPERO注册(CRD42024585478),按照PRISMA指南,检索Web of Science、PubMed、Ovid MEDLINE和Cochrane。质量评价采用Cochrane Collaboration的风险偏倚(risk of bias, RoB)工具。Review Manager v5.4用于分析。结果:定性纳入12项研究,定量纳入7项研究。结果包括主观膝关节评分(Lysholm, Tegner, IKDC)和股四头肌/腘绳肌力量测量。我们的研究结果表明,在一些研究中,以家庭为基础的治疗方案的主观膝关节评分提高了19%。然而,对于腘绳肌强度测量,监督方案更优越(SMD = -0.48, P = 0.02)。结论:总体而言,以家庭为基础的康复结果与有监督的功能恢复方案相当。然而,有监督的方法稍微增强了肌肉力量。虽然需要进一步的研究来评估其对恢复运动的影响,但建议监督康复以优化力量,特别是对运动员。
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引用次数: 0
Early weight-bearing after acetabular fractures in the older patient: a systematic review. 老年患者髋臼骨折后早期负重:一项系统综述。
IF 4 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-09-04 DOI: 10.1530/EOR-2024-0191
Marte I Lommerse, Anna H M Mennen, Frank W Bloemers, Hanna C Willems, Daphne van Embden

Purpose: While the incidence of acetabular fractures keeps rising among our older patient population, age-specific rehabilitation guidelines are lacking. Post-surgery weight-bearing is often restricted for 8-12 weeks to avoid secondary fixation failure. However, non- or restricted weight-bearing commonly results in atrophy, and older patients are at additional risk of long-term mobility and functionality loss. Therefore, if the risk of secondary fracture failure proves to be lower than currently believed, early or permissive weight-bearing might actually be the preferred treatment choice to advance fracture healing and decrease recovery time. This study aims to review the current literature on early weight-bearing outcomes of acetabular fractures in older adults.

Methods: A systematic search of two databases was conducted following PRISMA guidelines. Eligible studies reported on early weight-bearing outcomes of older patients after surgical management. Data were showed in tables alongside a narrative synthesis. Critical appraisal and risk-of-bias tools assessed the study quality.

Results: Six studies were included with a retrospective or observational design, with a total of 147 patients averaging 64 years old. The majority of studies discussed early weight-bearing protocols after percutaneous fixation (PF), with heterogeneity in terminology across protocols.

Conclusions: Albeit limited and low in evidence, the included studies suggest that early weight-bearing might be a possible alternative for non- or minimally displaced fractures and displaced fractures after PF and open reduction internal fixation, respectively. When risk assessments and functional outcomes are appropriately investigated, early weight-bearing may help patients, especially older adults, avoid suffering and prolonged rehabilitation periods.

目的:虽然老年患者髋臼骨折的发生率持续上升,但缺乏针对年龄的康复指南。术后通常限制负重8-12周,以避免二次固定失败。然而,非或限制性负重通常会导致肌肉萎缩,老年患者有长期活动能力和功能丧失的额外风险。因此,如果继发性骨折失败的风险比目前认为的要低,那么早期或允许负重可能实际上是促进骨折愈合和缩短恢复时间的首选治疗选择。本研究旨在回顾目前关于老年人髋臼骨折早期负重结局的文献。方法:按照PRISMA指南系统检索两个数据库。符合条件的研究报告了手术治疗后老年患者的早期负重结果。数据以表格形式显示,并附有叙述综合。关键评价和偏倚风险工具评估了研究质量。结果:6项研究纳入回顾性或观察性设计,共147例患者,平均年龄64岁。大多数研究讨论了经皮固定(PF)后的早期负重方案,不同方案的术语存在异质性。结论:虽然证据有限,但纳入的研究表明,早期负重可能是PF和切开复位内固定后非或最小移位骨折和移位骨折的可能替代方法。当风险评估和功能结果得到适当调查时,早期负重可能有助于患者,特别是老年人,避免痛苦和延长康复期。
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引用次数: 0
One-year mortality rates of fragility fractures of the pelvis: a systematic review and meta-analysis. 骨盆脆性骨折的一年死亡率:系统回顾和荟萃分析。
IF 4 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-09-04 DOI: 10.1530/EOR-2024-0164
Duy Nguyen Anh Tran, Chao-Yu Hsu, Pol Maria Rommens, Tan Thanh Nguyen, Yi-Jie Kuo, Shun-Jen Cheng, Yu-Pin Chen

Purpose: This study investigates the 1-year mortality of fragility fractures of the pelvis (FFP) in patients categorized under this system and treated with surgery or conservative methods, aiming to assess the algorithm's effectiveness.

Methods: We systematically searched PubMed, Embase, Scopus, and Web of Science for English studies on the 1-year mortality of FFP, with no publication date restrictions. Study quality was assessed using the Newcastle-Ottawa Scale. Pooled 1-year mortality rates were calculated using random-effects models. In addition, if applicable, odds ratios with 95% confidence intervals were employed. PRISMA guidelines were followed for reporting, and the study was registered with PROSPERO.

Results: Analysis of 22 studies encompassing 3,265 patients with FFP revealed a concerning overall 1-year mortality rate of 15.5%. Mortality varied by fracture type, with FFP IV having the lowest rate (7.5%) and FFP III having the highest (17.0%). All studies concurred on conservative treatment for FFP I. For other fracture types, mortality rates differed between conservative and surgical approaches. Conservative treatment resulted in rates of 14.9, 21.8, and 5.1% for FFP II, III, and IV, respectively. Conversely, surgical treatment yielded mortality rates of 16.8, 19.5, and 24.2% for FFP II, III, and IV, respectively.

Conclusion: Fragility fractures of the pelvis have high mortality, especially in FFP III. Conservative treatment may be suitable for FFP I, while surgery might be better for FFP III. The rarity of FFP IV fractures limits conclusions, and FFP II fractures lack a clear treatment consensus. Further research is needed to optimize management for these fracture types.

目的:本研究调查在该系统分类下接受手术或保守治疗的骨盆脆性骨折(FFP)患者的1年死亡率,旨在评估该算法的有效性。方法:我们系统地检索PubMed、Embase、Scopus和Web of Science关于FFP 1年死亡率的英文研究,没有发表日期限制。使用纽卡斯尔-渥太华量表评估研究质量。使用随机效应模型计算汇总的1年死亡率。此外,如果适用,采用95%置信区间的比值比。遵循PRISMA指南进行报告,该研究已在PROSPERO注册。结果:对包含3265例FFP患者的22项研究的分析显示,FFP的1年总死亡率为15.5%。不同骨折类型的死亡率不同,FFP IV的死亡率最低(7.5%),FFP III的死亡率最高(17.0%)。所有的研究都赞同保守治疗FFP i。对于其他类型的骨折,保守治疗和手术治疗的死亡率不同。保守治疗导致FFP II、III和IV的发生率分别为14.9%、21.8%和5.1%。相反,手术治疗的FFP II、III和IV的死亡率分别为16.8%、19.5%和24.2%。结论:骨盆脆性骨折病死率高,尤其是FFP III型。保守治疗可能适用于FFP I,而手术治疗可能对FFP III更好。FFP IV骨折的罕见性限制了结论,而FFP II骨折缺乏明确的治疗共识。需要进一步的研究来优化这些裂缝类型的管理。
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引用次数: 0
What do European shoulder surgeons think of the frozen shoulder? Results of a questionnaire survey among the members of the European Society for Surgery of the Shoulder and the Elbow and a review of the current evidence. 欧洲的肩部外科医生是如何看待冻肩的?对欧洲肩关节外科学会成员进行问卷调查的结果以及对现有证据的回顾。
IF 4 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-09-04 DOI: 10.1530/EOR-2024-0218
Anna Várnagy, Dániel S Veres, Gábor Skaliczki

The results of our survey conducted among the members of the European Society for Surgery of the Shoulder and the Elbow is presented in this article. The two most important features of frozen shoulder are movement restriction and pain. Frozen shoulder is considered secondary if it occurs after surgery or trauma. Corticosteroid injections are recommended as the first choice of pharmacological therapy. Patient education and physical therapy are the first choice of non-surgical therapy. The rate of remaining symptoms was observed in less than 20% of patients.

我们在欧洲肩关节外科学会成员中进行的调查结果在这篇文章中提出。肩周炎的两个最重要的特征是活动受限和疼痛。如果发生在手术或创伤之后,肩周炎被认为是继发性的。建议将皮质类固醇注射作为药物治疗的首选。患者教育和物理治疗是非手术治疗的首选。在不到20%的患者中观察到残留症状。
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引用次数: 0
Exploring superior capsular reconstruction and tendon transfers for massive irreparable posterosuperior rotator cuff tears. 探讨上囊重建和肌腱转移治疗大量不可修复的后上肩袖撕裂。
IF 4 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-09-04 DOI: 10.1530/EOR-2024-0139
Majd Mzeihem, Mohamad Nassereddine, Anas El Zouhbi, Farid Amirouche, Bassem Elhassan

Rotator cuff tears are prevalent, affecting 20% of the general population, with massive tears accounting for 40% of these cases. Massive tears, those larger than 5 cm or involving several tendons, pose substantial clinical problems, including poorer surgical outcomes and increased recurrence rates. Multiple classification systems offer varied definitions, complicating treatment strategies. The irreparability of these tears, exacerbated by conditions such as tendon atrophy and advanced imaging abnormalities, can further complicate management. Surgical options include superior capsular reconstruction (SCR) and tendon transfers. SCR, which involves attaching a graft to the superior glenoid and greater tuberosity, has shown promise in individuals with intact subscapularis tendons and minimal arthritis. Graft alternatives include fascia lata (FL) autografts, human dermal allografts, and long head of the biceps tendon (LHBT) autografts. Each graft type has distinct advantages and disadvantages, with FL autografts providing greater results despite donor site morbidity. Tendon transfers, such as latissimus dorsi and lower trapezius transfers, offer alternative treatments, especially for younger, more active individuals. This review thoroughly reviews different therapeutic options, emphasizing the most recent evidence and clinical outcomes to help guide the best management of massive posterosuperior irreparable rotator cuff injuries.

肩袖撕裂很普遍,影响20%的普通人群,其中大规模撕裂占40%。大于5厘米或涉及多个肌腱的大规模撕裂会造成严重的临床问题,包括手术效果较差和复发率增加。多种分类系统提供不同的定义,使治疗策略复杂化。这些撕裂的不可修复性,因肌腱萎缩和晚期影像学异常等情况而加剧,可能使治疗进一步复杂化。手术选择包括上囊重建(SCR)和肌腱转移。SCR包括将移植物附着于上盂关节和大结节,在肩胛下肌肌腱完整且关节炎轻微的个体中显示出希望。可选择的移植物包括阔筋膜(FL)自体移植物、人类真皮同种异体移植物和二头肌肌腱长头(LHBT)自体移植物。每种移植物类型都有不同的优点和缺点,尽管供体部位发病率高,但自体FL移植物的效果更好。肌腱转移,如背阔肌和下斜方肌转移,提供了另一种治疗方法,特别是对年轻、更活跃的个体。本综述全面回顾了不同的治疗方案,强调了最新的证据和临床结果,以帮助指导大规模后上不可修复的肩袖损伤的最佳治疗。
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引用次数: 0
Evolutionary patterns and future perspectives of joint replacement in arthritis patients: a comprehensive analysis of findings over the past decades. 关节炎患者关节置换的进化模式和未来前景:对过去几十年研究结果的综合分析。
IF 4 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-09-04 DOI: 10.1530/EOR-2025-0071
Sha-Sha Tao, Jian Tang, Yu-Chen Liu, Shu-Zhen Xu, Zhu Chen, Hai-Feng Pan

Purpose: This study aimed to comprehensively review the current research status and trends of joint replacement for arthritis patients worldwide.

Methods: Literature related to joint replacement for arthritis patients from 2004 to 2024 was extracted from the Web of Science Core Collection (WoSCC) database. A systematic qualitative and quantitative analysis of these publications was conducted. Visualization of results was achieved using CiteSpace and VOSviewer software.

Results: In total, 14,349 publications met the inclusion and exclusion criteria and were selected for further research. Keyword analysis revealed a clinical emphasis on optimizing surgical outcomes through advancements in total knee arthroplasty, total hip arthroplasty, and patient-centered metrics. Emerging research hotspots since 2020 included precision techniques such as robotic-assisted surgery, strategies to address periprosthetic joint infection, and the role of psychological factors such as depression and patient satisfaction. Temporal trends highlighted evolving priorities, including personalized alignment protocols, where the burst intensities of kinematic alignment and mechanical alignment were 16.33 and 13.79, respectively, as well as functional recovery and complication prevention. Historical dominance of rheumatoid arthritis research has transitioned to broader exploration of osteoarthritis management and technological innovations in surgical precision.

Conclusion: This study revealed a marked transition from rheumatoid arthritis-focused studies to innovations in osteoarthritis management and precision surgical techniques. Clinically, these findings emphasize the need to integrate technological advancements with multidisciplinary frameworks to standardize infection control, optimize implant durability, and enhance rehabilitation outcomes. Future efforts should prioritize personalized alignment strategies, evidence-based infection control protocols, and multidisciplinary rehabilitation frameworks to improve long-term functional outcomes.

目的:本研究旨在全面回顾国内外关节炎患者关节置换术的研究现状及发展趋势。方法:从Web of Science Core Collection (WoSCC)数据库中提取2004 - 2024年关节炎患者关节置换术相关文献。对这些出版物进行了系统的定性和定量分析。利用CiteSpace和VOSviewer软件实现结果的可视化。结果:符合纳入和排除标准的文献共14349篇,可供进一步研究。关键词分析显示,临床强调通过全膝关节置换术、全髋关节置换术和以患者为中心的指标来优化手术结果。自2020年以来,新兴的研究热点包括机器人辅助手术等精密技术,解决假体周围关节感染的策略,以及抑郁症和患者满意度等心理因素的作用。时间趋势突出了不断发展的优先事项,包括个性化对齐方案,其中运动学对齐和机械对齐的爆发强度分别为16.33和13.79,以及功能恢复和并发症预防。类风湿关节炎研究的历史优势已经过渡到骨关节炎管理和手术精度技术创新的更广泛的探索。结论:本研究揭示了从以类风湿关节炎为重点的研究到骨关节炎管理和精确手术技术创新的显著转变。在临床上,这些发现强调需要将技术进步与多学科框架相结合,以规范感染控制,优化种植体耐久性,提高康复效果。未来的努力应优先考虑个性化对齐策略、循证感染控制方案和多学科康复框架,以改善长期功能预后。
{"title":"Evolutionary patterns and future perspectives of joint replacement in arthritis patients: a comprehensive analysis of findings over the past decades.","authors":"Sha-Sha Tao, Jian Tang, Yu-Chen Liu, Shu-Zhen Xu, Zhu Chen, Hai-Feng Pan","doi":"10.1530/EOR-2025-0071","DOIUrl":"10.1530/EOR-2025-0071","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to comprehensively review the current research status and trends of joint replacement for arthritis patients worldwide.</p><p><strong>Methods: </strong>Literature related to joint replacement for arthritis patients from 2004 to 2024 was extracted from the Web of Science Core Collection (WoSCC) database. A systematic qualitative and quantitative analysis of these publications was conducted. Visualization of results was achieved using CiteSpace and VOSviewer software.</p><p><strong>Results: </strong>In total, 14,349 publications met the inclusion and exclusion criteria and were selected for further research. Keyword analysis revealed a clinical emphasis on optimizing surgical outcomes through advancements in total knee arthroplasty, total hip arthroplasty, and patient-centered metrics. Emerging research hotspots since 2020 included precision techniques such as robotic-assisted surgery, strategies to address periprosthetic joint infection, and the role of psychological factors such as depression and patient satisfaction. Temporal trends highlighted evolving priorities, including personalized alignment protocols, where the burst intensities of kinematic alignment and mechanical alignment were 16.33 and 13.79, respectively, as well as functional recovery and complication prevention. Historical dominance of rheumatoid arthritis research has transitioned to broader exploration of osteoarthritis management and technological innovations in surgical precision.</p><p><strong>Conclusion: </strong>This study revealed a marked transition from rheumatoid arthritis-focused studies to innovations in osteoarthritis management and precision surgical techniques. Clinically, these findings emphasize the need to integrate technological advancements with multidisciplinary frameworks to standardize infection control, optimize implant durability, and enhance rehabilitation outcomes. Future efforts should prioritize personalized alignment strategies, evidence-based infection control protocols, and multidisciplinary rehabilitation frameworks to improve long-term functional outcomes.</p>","PeriodicalId":48598,"journal":{"name":"Efort Open Reviews","volume":"10 9","pages":"646-659"},"PeriodicalIF":4.0,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12412288/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144993927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Coronal native limb alignment: establishing reporting standards and aligning measurements of key angles. 冠状原生肢体对准:建立报告标准和对准关键角度的测量。
IF 4 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-08-04 DOI: 10.1530/EOR-2024-0119

The main goal of a successful total knee arthroplasty is to relieve pain and restore function. While mechanical alignment provides excellent long-term implant survivorship, clinical and functional outcomes remain less than ideal. As a result, the focus has gradually shifted to a more personalized surgical approach based on the patient's specific characteristics. There is a pressing need for agreement on definitions of key terms to standardize limb alignment measurements and improve understanding and communication within the field. This work aims to clarify the concept of native limb alignment, outline how it is measured, and propose a standardized terminology to describe it.

成功的全膝关节置换术的主要目标是减轻疼痛和恢复功能。虽然机械对准提供了良好的长期种植体存活,但临床和功能结果仍然不理想。因此,重点逐渐转移到基于患者具体特征的更个性化的手术方法。迫切需要在关键术语的定义上达成一致,以标准化肢体对准测量并改善该领域内的理解和交流。本研究的目的是澄清原生肢体对齐的概念,概述如何测量,并提出一个标准化的术语来描述它。
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引用次数: 0
Risk factors and injury prevention strategies for hamstring injuries: a narrative review. 腿筋损伤的危险因素和损伤预防策略:一个叙述性的回顾。
IF 4 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-08-04 DOI: 10.1530/EOR-2024-0135
Akram Hagos, Amaan A Merchant, Babar Kayani, Adam T Yasen, Fares S Haddad

Hamstring injuries are a significant concern in high-speed running and kicking sports, contributing to a high incidence and recurrence rate among athletes. Anatomical and biomechanical properties of the hamstrings, especially the biceps femoris long head, make them susceptible to strain, contributing to the high injury rate observed in athletes. Key risk factors, including prior injury history, neuromuscular deficiencies, excessive load, and muscle-tendon architecture, have been identified as contributors to injury prevalence. Eccentric strengthening exercises, particularly the Nordic hamstring exercise, are highlighted for their effectiveness in reducing the incidence of hamstring injuries. Stretching protocols, when combined with strengthening exercises, have shown potential in enhancing muscle flexibility and reducing injury risk, although their standalone effectiveness remains a subject of ongoing research.

在高速跑步和踢腿运动中,腿筋损伤是一个重要的问题,在运动员中造成了很高的发病率和复发率。腘绳肌的解剖和生物力学特性,特别是股二头肌的长头,使其容易受到拉伤,导致运动员受伤率高。关键的危险因素,包括先前的损伤史、神经肌肉缺陷、过度负荷和肌肉肌腱结构,已被确定为损伤患病率的贡献者。偏心强化运动,特别是北欧腿筋运动,因其减少腿筋损伤的有效性而被强调。拉伸方案,当与强化锻炼相结合时,已经显示出增强肌肉灵活性和降低受伤风险的潜力,尽管它们单独的有效性仍然是一个正在进行的研究课题。
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引用次数: 0
Efficacy of pericapsular nerve group block for pain control and functional recovery after total hip arthroplasty: a systematic review and meta-analysis of randomized controlled trials. 全髋关节置换术后囊周神经群阻滞对疼痛控制和功能恢复的疗效:随机对照试验的系统回顾和荟萃分析。
IF 4 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-08-04 DOI: 10.1530/EOR-2024-0105
Yapeng Li, Feng Li, Zhijie Zhang, Jiayi Guo, Chen Yue

Purpose: The objective of this study was to assess the benefits of the PENG block on pain control and functional recovery.

Methods: Randomized controlled trials in PubMed, Web of Science, Embase, and the Cochrane Library were selected, and data were meta-analyzed using a random-effects model to estimate mean difference (MD) or standardized mean differences (SMD).

Results: Eleven trials involving 1,135 patients were included. The PENG block was associated with significantly lower total opioid consumption than sham/no block (MD: -25.23, 95% CI: -27.01 to -23.45, I 2 = 0%), as well as better functional recovery. The PENG block was noninferior to the suprainguinal fascia iliaca block regarding postoperative pain scores and functional recovery and had a significant reduction in total opioid consumption (MD: -8.25, 95% CI: -16.48 to -0.02, I 2 = 68%). The PENG block was associated with similar total opioid consumption and functional recovery as the periarticular anesthetic infiltration (PAI), but worse static pain scores at 12 h (SMD: 0.41, 95% CI: 0.08-0.75, I 2 = 51%) and dynamic pain scores at 48 h after surgery (SMD: 0.36, 95% CI: 0.08-0.64, I 2 = 0%).

Conclusions: While current evidence supports the PENG block as a viable alternative to other types of peripheral analgesia in THA, existing data remain insufficient to conclude that the PENG block outperforms other peripheral analgesia when it comes to pain control or functional recovery. More well-designed randomized controlled trials are needed in the future to thoroughly explore whether the PENG block has superiority over other analgesic techniques.

目的:本研究的目的是评估PENG阻滞对疼痛控制和功能恢复的益处。方法:选择PubMed、Web of Science、Embase和Cochrane图书馆的随机对照试验,采用随机效应模型对数据进行meta分析,估计平均差异(MD)或标准化平均差异(SMD)。结果:纳入11项试验,涉及1135例患者。与假/无阻断相比,PENG阻断与总阿片类药物消耗显著降低(MD: -25.23, 95% CI: -27.01至-23.45,I 2 = 0%)以及更好的功能恢复相关。在术后疼痛评分和功能恢复方面,彭阻滞不逊于腹股沟上髂筋膜阻滞,并且阿片类药物总消耗显著减少(MD: -8.25, 95% CI: -16.48至-0.02,I 2 = 68%)。彭阻滞与关节周围麻醉浸润(PAI)的总阿片类药物消耗和功能恢复相似,但术后12小时的静态疼痛评分(SMD: 0.41, 95% CI: 0.08-0.75, I 2 = 51%)和48小时的动态疼痛评分(SMD: 0.36, 95% CI: 0.08-0.64, I 2 = 0%)较差。结论:虽然目前的证据支持彭阻滞作为THA中其他类型外周镇痛的可行替代方案,但现有的数据仍然不足以得出彭阻滞在疼痛控制或功能恢复方面优于其他外周镇痛的结论。未来需要更多精心设计的随机对照试验来彻底探索PENG阻滞是否优于其他镇痛技术。
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引用次数: 0
The differential diagnostic potential of SPECT/CT to detect osteomyelitis in foot or ankle: a systematic review. SPECT/CT对足部或踝关节骨髓炎的鉴别诊断潜力:系统综述。
IF 4 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-08-04 DOI: 10.1530/EOR-2024-0049
Verena Sontheimer, Lars Kemna, Juri Ruf, Andreas Frodl, Jan Kühle, Hagen Schmal

Purpose: Diagnosing osteomyelitis in the foot/ankle region is challenging primarily due to anatomical constraints. While bone biopsy is the gold standard, non-invasive methods such as SPECT (single photon emission computed tomography) and MRI are sensitive but lack specificity. This study aims to evaluate SPECT/CT's potential, integrating functional and structural imaging, to improve osteomyelitis diagnosis in this region.

Methods: A systematic review following PRISMA guidelines and the Cochrane Handbook was conducted, including comprehensive research across major databases (inception to October 2022). Diagnostic studies using SPECT/CT for suspected foot/ankle bone lesions or inflammation were included. We carried out descriptive analysis, SROC curve generation, and calculated mean sensitivities and specificities. Subgroup analyses were conducted for various tracers, CT resolutions, and evaluation strategies. Sensitivity and heterogeneity analyses, bias risk, and publication bias were assessed.

Results: Eleven diagnostic studies (463 patients) were reviewed, with seven focusing on diabetic patients. Tracers included labeled leukocytes (WBC), antigranulocyte antibodies, phosphonates (BS), and gallium citrate. Clinical follow-up was the primary reference standard. Mean sensitivity of SPECT/CT for osteomyelitis diagnosis was 93.8% (95% CI: 89.7-96.4%), and specificity was 84.6% (95% CI: 65.1-94.2%). WBC SPECT/CT was more specific (79.4%) but less sensitive (89.2%) than BS SPECT/CT (specificity 46.5%, sensitivity 93.1%). Combined tracers yielded the highest mean specificity (96.4%).

Conclusion: SPECT/CT shows promising diagnostic performance for osteomyelitis in the foot/ankle region, especially when applying combined tracer methods. It is particularly advantageous in chronic, postoperative, and post-traumatic cases, offering added value compared to MRI.

目的:由于解剖学上的限制,诊断足/踝关节区域的骨髓炎具有挑战性。虽然骨活检是金标准,非侵入性方法,如SPECT(单光子发射计算机断层扫描)和MRI是敏感的,但缺乏特异性。本研究旨在评估SPECT/CT结合功能和结构成像的潜力,以提高该区域骨髓炎的诊断。方法:遵循PRISMA指南和Cochrane手册进行系统评价,包括对主要数据库(成立至2022年10月)的综合研究。使用SPECT/CT对疑似足/踝骨病变或炎症进行诊断研究。我们进行了描述性分析,SROC曲线生成,并计算了平均敏感性和特异性。对各种示踪剂、CT分辨率和评估策略进行亚组分析。评估敏感性和异质性分析、偏倚风险和发表偏倚。结果:回顾了11项诊断研究(463例),其中7项针对糖尿病患者。示踪剂包括标记白细胞(WBC)、抗粒细胞抗体、磷酸盐(BS)和柠檬酸镓。临床随访为主要参考标准。SPECT/CT诊断骨髓炎的平均敏感性为93.8% (95% CI: 89.7-96.4%),特异性为84.6% (95% CI: 65.1-94.2%)。WBC SPECT/CT比BS SPECT/CT特异性高(79.4%),敏感性低(89.2%)(特异性46.5%,敏感性93.1%)。联合示踪剂的平均特异性最高(96.4%)。结论:SPECT/CT对足/踝关节区域骨髓炎的诊断具有良好的表现,特别是在应用联合示踪方法时。与MRI相比,它在慢性、术后和创伤后病例中特别有利,提供了额外的价值。
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引用次数: 0
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