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Surgical Repair of Postinfarction Left Ventricular Pseudoaneurysm. 梗死后左心室假性动脉瘤的手术修复。
IF 0.9 4区 医学 Pub Date : 2024-10-01 DOI: 10.14503/THIJ-24-8405
Soon Jin Kim, Kyung Hwa Kim, Jong Hun Kim, Tae Yun Kim

Left ventricular pseudoaneurysm is a serious and rare disorder that usually develops after acute myocardial infarction. It can lead to potentially lethal mechanical complications, such as acute left ventricular free wall rupture. This report presents the case of a 64-year-old man with a left ventricular pseudoaneurysm and myocardial rupture that was managed by left ventricular restoration with aneurysmectomy and coronary artery bypass with 2 grafts.

左心室假性动脉瘤是一种严重而罕见的疾病,通常发生在急性心肌梗死之后。它可能导致潜在的致命性机械并发症,如急性左心室游离壁破裂。本报告介绍了一名 64 岁男性的病例,他患有左心室假性动脉瘤和心肌破裂,通过动脉瘤切除术和冠状动脉搭桥术治疗后恢复了左心室功能。
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引用次数: 0
Prevalence of Cardiometabolic Risk Factors in Women: Insights From the Houston HeartReach Study. 女性心脏代谢风险因素的普遍性:休斯顿 HeartReach 研究的启示。
IF 0.9 4区 医学 Pub Date : 2024-09-27 DOI: 10.14503/THIJ-24-8429
Arjun R Raghuram, Matthew W Segar, Stephanie Coulter, Joseph G Rogers

Background: Cardiovascular disease is the leading cause of death among women in the United States. Past research has highlighted the importance of the relationship between female-specific demographics and traditional risk factors. The present analysis aimed to identify the prevalence of modifiable risk factors in women attending a community cardiovascular health screening.

Methods: Data collected between 2011 and 2019 were obtained from the Houston HeartReach Registry. Participants were classified as having or not having each of 4 traditional cardiometabolic risk factors: hypertension, diabetes, body mass index indicating overweight or obesity, and dyslipidemia. Differences in prevalence were compared using the Pearson χ2 test.

Results: Most participants had hypertension, overweight or obesity, and dyslipidemia. Older women (≥65 years) had the highest prevalence of all cardiometabolic risk factors. Black participants had a higher prevalence of hypertension (P = .006) and a lower prevalence of dyslipidemia (P = .009) than non-Black participants. Hispanic participants had a lower prevalence of hypertension (P < .001) and a higher prevalence of overweight or obesity (P = .03) than non-Hispanic participants. Participants in the lowest household income bracket (<$25,000) were more likely to have diabetes (P = .001) and overweight or obesity (P = .004) than participants in the highest income bracket (≥$50,000). Unemployed participants had a higher prevalence of diabetes (P < .001), overweight or obesity (P = .004), and dyslipidemia (P < .001) than employed participants. Comorbidity analysis revealed clustering of multiple cardiometabolic risk factors. Moreover, risk factor hot spots were identified by zip code, which could help select future sites for targeted screening.

Conclusion: The analysis found that cardiometabolic risk factor prevalence varies with demographic and socioeconomic status. Geographic areas where cardiometabolic risk factor prevalence was highest were also identified. Further participant recruitment and analysis are required to create predictive models of cardiovascular disease risk in women.

背景:心血管疾病是导致美国女性死亡的主要原因。过去的研究强调了女性特有的人口统计学特征与传统风险因素之间关系的重要性。本分析旨在确定参加社区心血管健康筛查的女性中可改变风险因素的流行率:2011年至2019年期间收集的数据来自休斯顿HeartReach登记处。参与者被分类为是否具有以下 4 种传统心血管代谢风险因素:高血压、糖尿病、体重指数显示超重或肥胖以及血脂异常。采用 Pearson χ2 检验比较患病率的差异:结果:大多数参与者患有高血压、超重或肥胖以及血脂异常。老年妇女(≥65 岁)在所有心脏代谢风险因素中发病率最高。与非黑人参与者相比,黑人参与者的高血压患病率较高(P = .006),血脂异常患病率较低(P = .009)。与非西班牙裔参与者相比,西班牙裔参与者的高血压患病率较低(P < .001),超重或肥胖患病率较高(P = .03)。最低家庭收入阶层的参与者(结论:P = 0.001分析发现,心脏代谢风险因素的发生率因人口和社会经济状况而异。此外,还确定了心脏代谢风险因素流行率最高的地理区域。需要进一步招募参与者并进行分析,以建立女性心血管疾病风险预测模型。
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引用次数: 0
Recent Developments in Cardiac Contractility Modulation for Heart Failure. 心脏收缩力调节治疗心力衰竭的最新进展。
IF 0.9 4区 医学 Pub Date : 2024-09-17 DOI: 10.14503/THIJ-24-8464
Joshua R Hirsch, Hamid Afshar
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引用次数: 0
Valvular Endocarditis and Biventricular Heart Failure in the Setting of Tropheryma whipplei Disease. 瓣膜性心内膜炎和双心室性心力衰竭(Tropheryma whipplei Disease)。
IF 0.9 4区 医学 Pub Date : 2024-08-05 DOI: 10.14503/THIJ-23-8336
Defne Gunes Ergi, Hind J Fadel, Hector I Michelena, Grace Lin, Kevin L Greason, Arman Arghami

Whipple disease is a rare systemic illness associated with weight loss, diarrhea, and arthralgia. Asymptomatic carriage is common, but the disease can be complicated by cardiac involvement and may result in culture-negative endocarditis. Cardiac manifestations of the disease can lead to death. This report presents the case of a 66-year-old man with Whipple disease and biventricular heart failure with cardiogenic shock. Medical therapy followed by successful replacement of the aortic and mitral valves resulted in substantial improvement.

惠普尔病是一种罕见的全身性疾病,伴有体重减轻、腹泻和关节痛。无症状带菌很常见,但该病可因心脏受累而并发,并可能导致培养阴性的心内膜炎。该病的心脏表现可导致死亡。本报告介绍了一名 66 岁男性患者的病例,他患有 Whipple 病和双心室心力衰竭,并伴有心源性休克。在接受药物治疗后,成功置换了主动脉瓣和二尖瓣,病情得到显著改善。
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引用次数: 0
Cardiac Mass in a 78-Year-Old Patient With a History of Cancer: Diagnostic and Treatment Challenges. 一名 78 岁有癌症史患者的心脏肿块:诊断与治疗的挑战。
IF 0.9 4区 医学 Pub Date : 2024-08-02 DOI: 10.14503/THIJ-23-8299
Bihong Zhao, Ayah Zaqqa, Michelle M McDonald, Ismael A Salas de Armas, Igor D Gregoric, L Maximilian Buja

Primary cardiac angiosarcoma is a rare, aggressive malignancy that commonly metastasizes to various organs. The presenting symptoms are typically nonspecific, so a comprehensive examination is required to confirm the diagnosis promptly. This case report describes the presentation of an older patient with a history of neoplasms. Echocardiography and biopsy were performed, but despite surgical intervention to resect a large right atrial mass, the patient died. A final diagnosis of primary angiosarcoma was made based on the resected specimen.

原发性心脏血管肉瘤是一种罕见的侵袭性恶性肿瘤,通常会转移到各种器官。其症状通常没有特异性,因此需要进行全面检查才能及时确诊。本病例报告描述了一名有肿瘤病史的老年患者的表现。患者接受了超声心动图检查和活组织检查,尽管手术切除了一个巨大的右心房肿块,但患者还是死亡了。根据切除的标本,最终诊断为原发性血管肉瘤。
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引用次数: 0
Modern Perspectives on Hypertrophic Cardiomyopathy-No One Size Fits All. 肥厚型心肌病的现代视角--不能一刀切。
IF 0.9 4区 医学 Pub Date : 2024-08-01 DOI: 10.14503/THIJ-24-8423
Brett Doliner, Hadeel Gaddar, Ramsey Kalil, Alexander Postalian

Despite substantial advances in the management of hypertrophic cardiomyopathy, advanced heart failure remains a major cause of morbidity in this patient population. This narrative review presents the case of a patient with hypertrophic obstructive cardiomyopathy who underwent alcohol septal ablation to frame a discussion of modern therapies for hypertrophic cardiomyopathy. The current treatment landscape includes medications, both old and new, and surgical and procedural interventions to relieve mechanical obstruction. Several promising new modalities for relieving obstruction are in the nascent stages of development.

尽管肥厚型心肌病的治疗取得了长足的进步,但晚期心力衰竭仍然是导致这类患者发病的主要原因。这篇叙事性综述介绍了一名接受酒精房间隔消融术的肥厚型梗阻性心肌病患者的病例,并以此为框架讨论肥厚型心肌病的现代疗法。目前的治疗方法包括新旧药物、外科手术和程序干预,以缓解机械性梗阻。目前有几种很有前景的缓解梗阻的新方法正处于研发初期。
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引用次数: 0
Iatrogenic Atrial Septal Defect After MitraClip Transcatheter Edge-to-Edge Repair: To Close or Not to Close? MitraClip 经导管边缘到边缘修复术后的先天性房室隔缺损:关闭还是不关闭?
IF 0.9 4区 医学 Pub Date : 2024-07-31 DOI: 10.14503/THIJ-23-8337
Mariem Abdelsalam, Raghad Younus, Lamis F Abdalla, Abdelkader Almanfi

The evolution of percutaneous procedures that use transseptal puncture to treat left-sided structural heart disease has led to the emergence of iatrogenic atrial septal defects as a potential complication. These defects can result in hemodynamic decompensation and worsening clinical outcomes. Some iatrogenic atrial septal defects require immediate closure, others do not. This case report presents 2 patients who underwent transcatheter edge-to-edge mitral valve repair with transseptal puncture and required iatrogenic atrial septal defect closure (1 immediate and 1 delayed). The goal of this report is to highlight iatrogenic atrial septal defect assessment and the possible need for closure after transseptal puncture.

使用经皮穿刺治疗左侧结构性心脏病的经皮手术的发展导致了先天性房间隔缺损这一潜在并发症的出现。这些缺损可导致血流动力学失调和临床预后恶化。有些先天性房间隔缺损需要立即关闭,有些则不需要。本病例报告介绍了 2 例接受经导管二尖瓣边缘对边缘修复术并行经皮穿刺的患者,他们都需要进行先天性房间隔缺损关闭术(1 例立即关闭,1 例延迟关闭)。本报告的目的是强调先天性房间隔缺损的评估以及经房间隔穿刺后可能需要关闭的情况。
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引用次数: 0
Spontaneous Right Intrapetrous Internal Carotid Dissection in a Patient With Active COVID-19. 一名活动性 COVID-19 患者的自发性右颈内动脉交叉。
IF 0.9 4区 医学 Pub Date : 2024-07-25 DOI: 10.14503/THIJ-24-8403
Oscar Noble, Keri Sprung, Orlando Diaz, Stephanie Coulter, Eduardo Hernandez-Vila

Spontaneous cervical artery dissection, a nontraumatic tear in the wall of an internal carotid or vertebral artery, is a common cause of stroke, particularly in patients younger than 40 years of age; however, petrous internal carotid artery dissection is extremely rare. This case report describes a 50-year-old woman who had a spontaneous intrapetrous internal carotid dissection thought to be secondary to active SARS-CoV-2 infection; the dissection was treated successfully with a flow-diverter stent.

自发性颈动脉夹层是颈内动脉或椎动脉壁的非创伤性撕裂,是中风的常见原因,尤其是在 40 岁以下的患者中;然而,颈内动脉石刻状夹层极为罕见。本病例报告描述了一名 50 岁女性自发性颈内动脉瓣内夹层,被认为是继发于活动性 SARS-CoV-2 感染;夹层通过分流支架得到了成功治疗。
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引用次数: 0
Minimally Invasive Mitral Valve Surgery Using a Cold Fibrillatory Cardiac Arrest Technique in Patients With Prior Cardiac Surgery. 在接受过心脏手术的患者中使用冷颤性心脏停搏技术进行二尖瓣微创手术
IF 0.9 4区 医学 Pub Date : 2024-07-19 DOI: 10.14503/THIJ-23-8167
Ahmed Ali, Zachary Gray, Gabriel Loor, Alexis E Shafii, Todd K Rosengart, Kenneth K Liao

Objective: Minimally invasive mitral valve surgery (mini-MVS) is typically reserved for patients who have not undergone open cardiac surgery. In the reoperative setting, using intrapericardial dissection for crossclamping the aorta through a minimally invasive approach can be difficult and, at times, risky. Cold fibrillatory cardiac arrest (CFCA) with systemic cardiopulmonary bypass without cross-clamping is a well-described technique; however, data about its safety for patients who undergo reoperative mini-MVS are limited.

Methods: Data for 34 patients who underwent reoperative mini-MVS with CFCA from March 2017 to March 2022 were reviewed retrospectively. A mini right thoracotomy (n = 30) or robotic (n = 4) approach was used. Systemic hypothermia was induced to a target temperature of 25 °C.

Results: Patient mean (SD) age was 64.5 (9.6) years, and 15 of 34 (44.1%) patients were women. Of those 34 patients, 23 (67.6%) had severe regurgitation, and 11 (32.4%) had severe stenosis. Before mini-MVS, 28 patients had undergone valve surgery, and 8 had undergone coronary artery bypass graft surgery. The mitral valve was repaired in 5 of 34 (14.7%) and replaced in 29 of 34 (85.3%) patients. No difference was observed in preoperative and postoperative left ventricular function (P = .82). In 1 patient, kidney failure developed that necessitated dialysis. No postoperative stroke or mortality at 30 days occurred.

Conclusion: Mini-MVS with CFCA is well tolerated in patients with prior cardiac surgery. Myocardial function was not impaired, nor was the risk of stroke increased in this cohort, indicating that CFCA is a safe alternative in this high-risk population.

目的:微创二尖瓣手术(mini-MVS)通常只适用于未接受过心脏开放手术的患者。在再次手术的情况下,通过微创方法使用心包内剥离术横断主动脉可能会很困难,有时还会有风险。冷纤颤性心脏停搏(CFCA)配合全身心肺旁路而不进行横切是一种描述详尽的技术;然而,有关其对接受再手术微型心血管系统患者安全性的数据却很有限:方法:回顾性分析了2017年3月至2022年3月期间34名接受CFCA再手术迷你MVS患者的数据。采用迷你右胸廓切开术(n = 30)或机器人(n = 4)方法。全身低温诱导至目标温度25 °C:患者平均(标清)年龄为 64.5(9.6)岁,34 名患者中有 15 名(44.1%)为女性。在这 34 名患者中,23 人(67.6%)有严重的反流,11 人(32.4%)有严重的狭窄。在进行 mini-MVS 之前,28 名患者接受过瓣膜手术,8 名患者接受过冠状动脉旁路移植手术。34 位患者中有 5 位(14.7%)接受了二尖瓣修复手术,34 位患者中有 29 位(85.3%)接受了二尖瓣置换手术。术前和术后左心室功能无差异(P = .82)。一名患者出现肾衰竭,需要进行透析。术后 30 天未发生中风或死亡:结论:曾接受过心脏手术的患者对使用 CFCA 的 Mini-MVS 耐受良好。该组患者的心肌功能未受损,中风风险也未增加,这表明 CFCA 是此类高危人群的安全替代选择。
{"title":"Minimally Invasive Mitral Valve Surgery Using a Cold Fibrillatory Cardiac Arrest Technique in Patients With Prior Cardiac Surgery.","authors":"Ahmed Ali, Zachary Gray, Gabriel Loor, Alexis E Shafii, Todd K Rosengart, Kenneth K Liao","doi":"10.14503/THIJ-23-8167","DOIUrl":"10.14503/THIJ-23-8167","url":null,"abstract":"<p><strong>Objective: </strong>Minimally invasive mitral valve surgery (mini-MVS) is typically reserved for patients who have not undergone open cardiac surgery. In the reoperative setting, using intrapericardial dissection for crossclamping the aorta through a minimally invasive approach can be difficult and, at times, risky. Cold fibrillatory cardiac arrest (CFCA) with systemic cardiopulmonary bypass without cross-clamping is a well-described technique; however, data about its safety for patients who undergo reoperative mini-MVS are limited.</p><p><strong>Methods: </strong>Data for 34 patients who underwent reoperative mini-MVS with CFCA from March 2017 to March 2022 were reviewed retrospectively. A mini right thoracotomy (n = 30) or robotic (n = 4) approach was used. Systemic hypothermia was induced to a target temperature of 25 °C.</p><p><strong>Results: </strong>Patient mean (SD) age was 64.5 (9.6) years, and 15 of 34 (44.1%) patients were women. Of those 34 patients, 23 (67.6%) had severe regurgitation, and 11 (32.4%) had severe stenosis. Before mini-MVS, 28 patients had undergone valve surgery, and 8 had undergone coronary artery bypass graft surgery. The mitral valve was repaired in 5 of 34 (14.7%) and replaced in 29 of 34 (85.3%) patients. No difference was observed in preoperative and postoperative left ventricular function (P = .82). In 1 patient, kidney failure developed that necessitated dialysis. No postoperative stroke or mortality at 30 days occurred.</p><p><strong>Conclusion: </strong>Mini-MVS with CFCA is well tolerated in patients with prior cardiac surgery. Myocardial function was not impaired, nor was the risk of stroke increased in this cohort, indicating that CFCA is a safe alternative in this high-risk population.</p>","PeriodicalId":48680,"journal":{"name":"Texas Heart Institute Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11258755/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141727993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Artificial Chordae Implantation vs Posterior Leaflet Preservation: A Comparison of Midterm Results After Mitral Valve Replacement. 人工腱膜植入与后叶保留:二尖瓣置换术后中期效果比较。
IF 0.9 4区 医学 Pub Date : 2024-07-19 DOI: 10.14503/THIJ-23-8291
Salih Salihi, Bilhan Özalp, Fatih Toptan, Ibrahim Kara

Background: Various techniques have been proposed for the preservation of the subvalvular apparatus (SVA) in mitral valve replacement. This study aimed to compare the midterm results of posterior leaflet preservation with the results of selective preservation of the SVA involving artificial chordae implantation in terms of left ventricular performance in patients undergoing mitral valve replacement.

Methods: In total, 127 patients were included in this study. Patients were allocated to 1 of 2 groups according to the techniques used to preserve the SVA. Patients in group 1 underwent posterior leaflet preservation: The anterior leaflet was completely resected, and the posterior leaflet was preserved. In group 2, which comprised patients with severe leaflet extension and subvalvular fusion, the mitral valve was excised completely and substituted with artificial chordae. All relevant preoperative, intraoperative, and postoperative data were recorded.

Results: Mean (SD) ages in groups 1 and 2 were 63.1 (9.65) and 57.1 (12.3) years, respectively (P = .003). Mean (SD) follow-up time was 59.97 (23.63) months (range, 6-99 months). Left ventricular end-diastolic diameter decreased significantly after artificial chordae implantation (P < .001), while the decrease after posterior leaflet preservation was not statistically significant (P = .20). In both groups, there were statistically significant reductions (P < .001) in left ventricular end-systolic diameter and left atrium diameter in the postoperative period compared with respective preoperative levels. During follow-up, left ventricular ejection fraction was found to have increased beyond the preoperative levels in both groups, but the differences were not statistically significant (P > .05).

Conclusion: Results of echocardiographic observations regarding the preservation of the SVA via artificial chordae implantation for mitral valve disease in this sample were satisfactory. Findings suggest that artificial chordae implantation should be considered when posterior leaflet preservation is not suitable.

背景:在二尖瓣置换术中,有多种保留瓣下装置(SVA)的技术被提出。本研究旨在比较二尖瓣置换术中保留后瓣叶与选择性保留瓣下装置(包括人工腱膜植入)在左室功能方面的中期效果:本研究共纳入 127 例患者。根据保留 SVA 的技术将患者分为两组。第一组患者接受后瓣叶保留术:前叶完全切除,后叶保留。第二组包括严重瓣叶延伸和瓣下融合的患者,完全切除二尖瓣并用人工腱膜替代。所有相关的术前、术中和术后数据均已记录:第一组和第二组的平均(标清)年龄分别为 63.1(9.65)岁和 57.1(12.3)岁(P = .003)。平均(标清)随访时间为 59.97 (23.63) 个月(6-99 个月)。人工腱索植入术后左心室舒张末期直径明显缩小(P < .001),而后叶保留术后的缩小无统计学意义(P = .20)。与术前水平相比,两组患者术后左室收缩末期直径和左心房直径均有统计学意义的显著下降(P < .001)。随访期间发现,两组患者的左室射血分数都比术前有所增加,但差异无统计学意义(P > .05):结论:该样本中通过人工腱索植入治疗二尖瓣疾病保留SVA的超声心动图观察结果令人满意。研究结果表明,在不适合保留后叶的情况下,应考虑人工腱膜植入术。
{"title":"Artificial Chordae Implantation vs Posterior Leaflet Preservation: A Comparison of Midterm Results After Mitral Valve Replacement.","authors":"Salih Salihi, Bilhan Özalp, Fatih Toptan, Ibrahim Kara","doi":"10.14503/THIJ-23-8291","DOIUrl":"10.14503/THIJ-23-8291","url":null,"abstract":"<p><strong>Background: </strong>Various techniques have been proposed for the preservation of the subvalvular apparatus (SVA) in mitral valve replacement. This study aimed to compare the midterm results of posterior leaflet preservation with the results of selective preservation of the SVA involving artificial chordae implantation in terms of left ventricular performance in patients undergoing mitral valve replacement.</p><p><strong>Methods: </strong>In total, 127 patients were included in this study. Patients were allocated to 1 of 2 groups according to the techniques used to preserve the SVA. Patients in group 1 underwent posterior leaflet preservation: The anterior leaflet was completely resected, and the posterior leaflet was preserved. In group 2, which comprised patients with severe leaflet extension and subvalvular fusion, the mitral valve was excised completely and substituted with artificial chordae. All relevant preoperative, intraoperative, and postoperative data were recorded.</p><p><strong>Results: </strong>Mean (SD) ages in groups 1 and 2 were 63.1 (9.65) and 57.1 (12.3) years, respectively (P = .003). Mean (SD) follow-up time was 59.97 (23.63) months (range, 6-99 months). Left ventricular end-diastolic diameter decreased significantly after artificial chordae implantation (P < .001), while the decrease after posterior leaflet preservation was not statistically significant (P = .20). In both groups, there were statistically significant reductions (P < .001) in left ventricular end-systolic diameter and left atrium diameter in the postoperative period compared with respective preoperative levels. During follow-up, left ventricular ejection fraction was found to have increased beyond the preoperative levels in both groups, but the differences were not statistically significant (P > .05).</p><p><strong>Conclusion: </strong>Results of echocardiographic observations regarding the preservation of the SVA via artificial chordae implantation for mitral valve disease in this sample were satisfactory. Findings suggest that artificial chordae implantation should be considered when posterior leaflet preservation is not suitable.</p>","PeriodicalId":48680,"journal":{"name":"Texas Heart Institute Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11258753/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141727992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Texas Heart Institute Journal
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