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Ethical Principles in Plastic Surgery Research 整形外科研究的伦理原则
IF 2 3区 医学 Q2 SURGERY Pub Date : 2024-02-08 DOI: 10.1055/s-0043-1778045
Research is an integral part of medical progress that leads to better understanding of disease processes and the development of therapies to improve patient care. The medical community has an obligation and societal responsibility to review its practices and advance its knowledge to optimize care for those who entrust it with their health and well-being. While ultimately intended to benefit patients specifically and society as a whole, every laboratory and clinical investigation inherently carries an element of uncertainty and has attendant risks. These can have unintended and, at times, harmful consequences that cannot justify the knowledge gained. In order to mitigate these risks and protect human subjects involved in clinical research studies, a basic framework of ethical principles has been developed to guide responsible experimental design, execution, and data dissemination. This article provides a review of these principles and the historical context from which they were derived and explores the persistent challenges and cognitive biases that can increase susceptibility to unethical research practices.
研究是医学进步不可或缺的一部分,它能让人们更好地了解疾病的过程,并开发出改善病人护理的疗法。医学界有义务和社会责任对其实践进行审查,并增进其知识,以优化对那些将健康和福祉托付给医学界的人的护理。虽然每项实验室和临床研究最终都是为了造福患者和整个社会,但其本身也存在不确定性因素和相应的风险。这些风险可能会带来意想不到的后果,有时甚至是有害的后果,无法弥补所获得的知识。为了降低这些风险并保护参与临床研究的人类受试者,我们制定了一个基本的伦理原则框架,以指导负责任的实验设计、执行和数据传播。本文回顾了这些原则及其产生的历史背景,并探讨了可能增加不道德研究行为易感性的长期挑战和认知偏差。
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引用次数: 0
Merging Humans and Neuroprosthetics through Regenerative Peripheral Nerve Interfaces 通过再生外周神经接口实现人类与神经假肢的融合
IF 2 3区 医学 Q2 SURGERY Pub Date : 2024-02-06 DOI: 10.1055/s-0044-1779028
Limb amputations can be devastating and significantly affect an individual's independence, leading to functional and psychosocial challenges in nearly 2 million people in the United States alone. Over the past decade, robotic devices driven by neural signals such as neuroprostheses have shown great potential to restore the lost function of limbs, allowing amputees to regain movement and sensation. However, current neuroprosthetic interfaces have challenges in both signal quality and long-term stability. To overcome these limitations and work toward creating bionic limbs, the Neuromuscular Laboratory at University of Michigan Plastic Surgery has developed the Regenerative Peripheral Nerve Interface (RPNI). This surgical construct embeds a transected peripheral nerve into a free muscle graft, effectively amplifying small peripheral nerve signals to provide enhanced control signals for a neuroprosthetic limb. Furthermore, the RPNI has the potential to provide sensory feedback to the user and facilitate neuroprosthesis embodiment. This review focuses on the animal studies and clinical trials of the RPNI to recapitulate the promising trajectory toward neurobionics where the boundary between an artificial device and the human body becomes indistinct. This paper also sheds light on the prospects of the improvement and dissemination of the RPNI technology.
肢体截肢可能是毁灭性的,严重影响个人的独立性,仅在美国就有近 200 万人因此面临功能和社会心理方面的挑战。在过去十年中,由神经信号驱动的机器人设备(如神经义肢)已显示出恢复肢体丧失功能的巨大潜力,使截肢者能够重新获得运动和感觉。然而,目前的神经义肢接口在信号质量和长期稳定性方面都存在挑战。为了克服这些限制并努力创造仿生肢体,密歇根大学整形外科神经肌肉实验室开发了再生外周神经接口(RPNI)。这种手术结构将切断的外周神经嵌入游离肌肉移植中,有效地放大了微小的外周神经信号,为神经义肢提供更强的控制信号。此外,RPNI 还有可能为使用者提供感觉反馈,促进神经假肢的实现。本综述侧重于 RPNI 的动物研究和临床试验,以重现神经仿生学的发展轨迹,即人工设备与人体之间的界限变得模糊不清。本文还揭示了 RPNI 技术的改进和推广前景。
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引用次数: 0
60 Years of Michigan Plastic Surgery 密歇根整形外科 60 年历史
IF 2 3区 医学 Q2 SURGERY Pub Date : 2024-02-05 DOI: 10.1055/s-0043-1778035
Ipek Berberoglu, Katherine L. Burke, Robert H. Gilman, Steven Kasten, Paul S. Cederna, Stephen W.P. Kemp

In 1964, the Section of Plastic and Reconstructive Surgery at the University of Michigan opened its doors to future surgeons and leaders in the field. Today, we are celebrating the 60-year history of the program and its significant contributions to the field. Beginning under the leadership of Reed O. Dingman, MD, DDS, the program began with three faculty members and two independent surgical residents. Since that time, it has expanded dramatically to include 24 faculty members and 28 integrated plastic surgery residents. The goals of the program have always been to achieve excellence in all three of our academic missions including clinical care, teaching, and research. Annually, the program sees an average of 35,000 outpatient clinic visits, 4,000 major operations, 200 peer-reviewed publications, $5,000,000 in research spending, and residents who are well trained and highly competitive for fellowships of their choosing every single year. Through scientific collaborations, academic exchanges, and medical missions, the program's influence has spread beyond Michigan, reaching the entire world. In addition to training world-renowned surgeons, Michigan's faculty and graduates have assumed leadership roles in prestigious professional organizations, scientific journals, and research foundations. In this article, we explore the roots of the program and reflect on six decades of impact, innovation, and inspiration.

1964 年,密歇根大学整形外科向未来的外科医生和该领域的领军人物敞开了大门。今天,我们正在庆祝该项目 60 年的历史及其对该领域的重大贡献。在医学博士里德-O-丁曼(Reed O. Dingman)的领导下,该项目开始时只有三名教师和两名独立的外科住院医师。从那时起,它的规模急剧扩大,现已拥有 24 名教师和 28 名综合整形外科住院医师。本项目的目标一直是在临床护理、教学和研究等三项学术任务中取得优异成绩。每年,该项目平均门诊量达 35,000 人次,大型手术 4,000 例,发表同行评审论文 200 篇,科研支出达 5,000,000 美元,住院医师训练有素,每年都有很强的竞争力获得自己选择的奖学金。通过科学合作、学术交流和医疗任务,该计划的影响力已超越密歇根州,遍及全世界。除了培养世界知名的外科医生,密歇根的教师和毕业生还在著名的专业组织、科学杂志和研究基金会中担任领导职务。在这篇文章中,我们将探究该计划的根源,并回顾六十年来的影响、创新和灵感。
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引用次数: 0
Regenerative Peripheral Nerve Interface Surgery for the Management of Chronic Posttraumatic Neuropathic Pain 外周神经接口再生手术治疗慢性创伤后神经病理性疼痛
IF 2 3区 医学 Q2 SURGERY Pub Date : 2024-01-19 DOI: 10.1055/s-0043-1778078
Jennifer C. Lee, Stephen W.P. Kemp, Theodore A. Kung

Chronic pain resulting from peripheral nerve injury remains a common issue in the United States and affects 7 to 10% of the population. Regenerative Peripheral Nerve Interface (RPNI) surgery is an innovative surgical procedure designed to treat posttraumatic neuropathic pain, particularly when a symptomatic neuroma is present on clinical exam. RPNI surgery involves implantation of a transected peripheral nerve into an autologous free muscle graft to provide denervated targets to regenerating axons. RPNI surgery has been found in animal and human studies to be highly effective in addressing postamputation pain. While most studies have reported its uses in the amputation patient population for the treatment of neuroma and phantom limb pain, RPNI surgery has recently been used to address refractory headache, postmastectomy pain, and painful donor sites from the harvest of neurotized flaps. This review summarizes the current understanding of RPNI surgery for the treatment of chronic neuropathic pain.

外周神经损伤导致的慢性疼痛在美国仍是一个常见问题,影响着7%到10%的人口。再生周围神经接口(RPNI)手术是一种创新的外科手术,旨在治疗创伤后神经病理性疼痛,尤其是在临床检查中发现有症状的神经瘤时。RPNI 手术是将横断的周围神经植入自体游离肌肉移植中,为再生轴突提供去神经支配靶点。动物和人体研究发现,RPNI 手术对解决截肢后疼痛非常有效。虽然大多数研究报告称 RPNI 手术用于治疗截肢患者的神经瘤和幻肢痛,但最近它也被用于治疗难治性头痛、乳房切除术后疼痛以及神经化皮瓣切除后供体部位疼痛。本综述总结了目前对 RPNI 手术治疗慢性神经病理性疼痛的理解。
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引用次数: 0
H Vessel Formation as a Marker for Enhanced Bone Healing in Irradiated Distraction Osteogenesis H 血管形成是辐照牵引成骨过程中骨愈合增强的标志物
IF 2 3区 医学 Q2 SURGERY Pub Date : 2024-01-19 DOI: 10.1055/s-0043-1778039
Melissa Daniel, Nathan Sheppard, Garrison Carlos, Noah Nelson, Alex Donneys, Steven R. Buchman
<p>In the setting of bone defects, the injured vasculature and loss of hemodynamic inflow leads to hematoma formation and low oxygen tension which stimulates vascular expansion through the HIf-1α pathway. Most importantly, this pathway upregulates sprouting of type H vessels (CD31hiEmcnhi vessels). H vessels engage in direct interaction with perivascular osteoprogenitor cells (OPCs), osteoblasts, and preosteoclasts of bone formation and remodeling. This angiogenic-osteogenic coupling leads to synchronous propagation of vascular and bony tissue for regenerative healing. A growing body of literature demonstrates that H vessels constitute a large portion of bone's innate capacity for osteogenic healing. We believe that CD31hiEmcnhi vessels play a role in bone healing during distraction osteogenesis (DO). DO is a procedure that utilizes traction forces to facilitate induction of endogenous bone formation and regeneration of surrounding soft tissues such as skin, muscle, tendon, and neurovascular structures. While the H vessel response to mechanical injury is adequate to facilitate healing in normal healthy tissue, it remains inadequate to overcome the devastation of radiation. We posit that the destruction of CD31hiEmcnhi vessels plays a role in precluding DO's effectiveness in irradiated bone defect healing. We aim, therefore, to recapitulate the normal pathway of bony healing by utilizing the regenerative capacity of H vessels. We hypothesize that using localized application of deferoxamine (DFO) will enhance the H vessel-mediated vasculogenic response to radiation damage and ultimately enable osteogenic healing during DO. This discovery could potentially be exploited by developing translational therapeutics to hopefully accelerate bone formation and shorten the DO consolidation period, thereby potentially expanding DO's utilization in irradiated bone healing.</p> <p>Sprague–Dawley rats were divided into three groups: DO, radiation with DO (xDO), and radiation with DO and DFO implantation (xDODFO). Experimental groups received 35 Gy of radiation. All groups underwent DO. The treatment group received injections into the osteotomy site, every other day, beginning on postoperative day (POD) 4 of DFO. Animals were sacrificed on POD 40. For immunohistochemical analysis, mandibles were dissected and fixed in 4% paraformaldehyde for 48 hours, decalcified in Cal-Ex II for 2 days, dehydrated through graded ethanol of increasing concentration, and then embedded in paraffin. Samples were cut into 7-μm thick longitudinally oriented sections including the metaphysis and diaphysis. CD31 and Emcn double immunofluorescent staining were performed to evaluate the extent of CD31hiEmcnhi vessel formation. Bone sections were then stained with conjugated antibodies overnight at 4°C. Nuclei were stained with Hoechst. Slides were also double stained with Osterix and CD31 to study the quantity of H vessel-mediated recruitment of OPCs to accelerate bone healing. Images were
在骨缺损的情况下,受伤的血管和血液动力流入的丧失会导致血肿形成和低氧张力,从而通过 HIf-1α 途径刺激血管扩张。最重要的是,这一途径会上调 H 型血管(CD31hiEmcnhi 血管)的萌发。H 型血管与血管周围的成骨细胞(OPCs)、成骨细胞以及骨形成和重塑过程中的前破骨细胞直接相互作用。这种血管生成与骨生成的耦合导致血管和骨组织的同步繁殖,从而实现再生愈合。越来越多的文献表明,H 血管在骨的先天成骨愈合能力中占了很大一部分。我们认为,CD31hiEmcnhi 血管在牵张成骨(DO)过程中对骨愈合起作用。牵引成骨是一种利用牵引力促进内源性骨形成和周围软组织(如皮肤、肌肉、肌腱和神经血管结构)再生的过程。虽然 H 血管对机械损伤的反应足以促进正常健康组织的愈合,但仍不足以克服辐射的破坏。我们认为,CD31hiEmcnhi 血管的破坏阻碍了 DO 在辐照骨缺损愈合中的有效性。因此,我们希望通过利用 H 血管的再生能力来重现骨骼愈合的正常途径。我们假设,局部应用去氧胺(DFO)将增强 H 血管介导的血管生成对辐射损伤的反应,并最终在 DO 过程中实现骨生成愈合。这一发现有可能被用于开发转化治疗药物,从而有望加速骨形成并缩短DO巩固期,从而有可能扩大DO在辐照骨愈合中的应用。Sprague-Dawley 大鼠被分为三组:DO组、DO辐射组(xDO)、DO和DFO植入辐射组(xDODFO)。实验组接受 35 Gy 的辐射。所有组均接受 DO。治疗组从 DFO 术后第 4 天(POD)开始,每隔一天向截骨部位注射一次。动物于术后第 40 天处死。为了进行免疫组化分析,解剖下颌骨并将其在 4% 多聚甲醛中固定 48 小时,在 Cal-Ex II 中脱钙 2 天,用浓度递增的分级乙醇脱水,然后用石蜡包埋。将样本切成7微米厚的纵向切片,包括干骺端和干骺端。进行 CD31 和 Emcn 双免疫荧光染色,以评估 CD31hiEmcnhi 血管形成的程度。然后在 4°C 下用共轭抗体对骨切片染色过夜。细胞核用 Hoechst 染色。切片还用 Osterix 和 CD31 进行双重染色,以研究 H 血管介导的 OPCs 募集数量,从而加速骨愈合。使用尼康 Ti2 宽场显微镜采集图像,并使用 NIS- Elements Advanced Research 5.41.02 软件进行分析。再生样本中 CD31 + Emcn+ 血管的面积分数代表 H 型血管的丰度。再生样本中 Osterix+ 细胞的面积分数代表 OPC 同时向分流间隙增殖的情况。DO 组的 H 型血管比 xDO 组多 6 倍。与 xDO 相比,局部 DFO 使辐照 DO 动物的 H 型血管数量明显增加了 15 倍(p = 0.00133531)。此外,H型血管丰富度更高的DO组和xDODFO组也表现出更好的血管生成和成骨效果。有趣的是,与 DO 组相比,xDODFO 组的 H 型血管形成量增加了一倍,这表明存在超生理反应(p = 0.044655055)。此外,H 血管介导的 OPCs 招募模拟了我们研究组中描述的 H 血管形成趋势。与 DO 对照组相比,辐照 DO 组的 OPCs 含量减少了 3 倍。对 xDO 动物进行 DFO 处理后,辐照损伤得到补救,Osterix+ 细胞的含量增加了 12 倍。最后,与 DO 对照组相比,对辐照动物进行 DFO 处理后,骨生成细胞招募到牵张间隙的数量增加了四倍。在这项研究中,我们开发了一种新方法来观察石蜡切片中的 CD31hiEmcnhi,以研究 DO 的再生。正常 DO 表现出 H 血管形成和相关血管生成-骨生成耦合的显著上调。辐射严重减少了H血管的形成,同时也显著减少了新骨的形成和不愈合。然而,服用 DFO 后,血管得到补充,大量 CD31hiEmcnhi 和 OPC 恢复,重现了骨再生和修复的正常过程。DFO治疗可修复辐照区域的新骨形成和骨结合,这与H血管血管生成-骨生成耦合的增加有关。 虽然还需要进一步的研究来优化这种方法,但这项研究的结果对于将期待已久的局部 DFO 应用于临床领域来说,具有令人难以置信的前景。
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引用次数: 0
Financial Toxicity in Breast Reconstruction: The Role of the Surgeon-Patient Cost-of-Care Discussion 乳房再造中的经济毒性:外科医生与患者讨论护理成本的作用
IF 2 3区 医学 Q2 SURGERY Pub Date : 2024-01-19 DOI: 10.1055/s-0043-1778040
Brigit D. Baglien, Nishant Ganesh Kumar, Nicholas L. Berlin, Sarah T. Hawley, Reshma Jagsi, Adeyiza O. Momoh

The financial burden of breast cancer treatment and reconstruction is a significant concern for patients. Patient desire for preoperative cost-of-care counseling while navigating the reconstructive process remains unknown. A cross-sectional survey of women from the Love Research Army was conducted. An electronic survey was distributed to women over 18 years of age and at least 1 year after postmastectomy breast reconstruction. Descriptive statistics and multivariable modeling were used to determine desire for and occurrence of cost-of-care discussions, and factors associated with preference for such discussions. Secondary outcomes included the association of financial toxicity with desire for cost discussions. Among 839 women who responded, 620 women (74.1%) did not speak to their plastic surgeon and 480 (57.4%) did not speak to a staff member regarding costs of breast reconstruction. Of the 550 women who reported it would have been helpful to discuss costs, 315 (57.3%) were not engaged in a financial conversation initiated by a health care provider. A greater proportion of women who reported financial toxicity, compared to those who did not, would have preferred to discuss costs with their plastic surgeon (65.2% vs. 43.5%, p < 0.001) or a staff member (75.5% vs. 59.3%, p < 0.001). Among women with financial toxicity, those who had some form of insurance (private, Medicaid, Medicare, “other”) were significantly more likely to prefer a cost-of-care discussion (p < 0.001, p = 0.02, p = 0.05, p = 0.01). Financial discussions about the potential costs of breast reconstruction seldom occurred in this national cohort. Given the reported preference and unmet need for financial discussions by a majority of women, better cost transparency and communication is needed.

乳腺癌治疗和重建的经济负担是患者非常关心的问题。患者在进行乳房再造手术时,对术前费用咨询的需求仍是未知数。我们对 "爱的研究军团 "的女性进行了一项横断面调查。调查对象为年满 18 周岁、乳房切除术后乳房再造至少 1 年的女性。调查采用了描述性统计和多变量模型来确定护理成本讨论的愿望和发生率,以及与偏好此类讨论相关的因素。次要结果包括财务毒性与费用讨论意愿的关联。在作出回复的 839 名妇女中,有 620 名妇女(74.1%)没有与整形外科医生讨论过乳房再造的费用,480 名妇女(57.4%)没有与工作人员讨论过乳房再造的费用。在 550 位表示讨论费用会有帮助的女性中,有 315 位(57.3%)没有参与过由医疗服务提供者发起的财务对话。与未报告财务问题的女性相比,报告财务问题的女性更愿意与整形外科医生讨论费用问题(65.2% 对 43.5%,p p p = 0.02,p = 0.05,p = 0.01)。在这个全国性队列中,有关乳房重建潜在成本的财务讨论很少发生。考虑到大多数女性对财务讨论的偏好和需求未得到满足,因此需要提高成本透明度并加强沟通。
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引用次数: 0
Management of Neuropathic Pain with Neurectomy Combined with Dermal Sensory Regenerative Peripheral Nerve Interface (DS-RPNI) 神经切除术结合真皮感觉再生外周神经接口(DS-RPNI)治疗神经病理性疼痛
IF 2 3区 医学 Q2 SURGERY Pub Date : 2024-01-19 DOI: 10.1055/s-0043-1778041
Geoffrey E. Hespe, David L. Brown

Neuropathic pain affects a large percentage of the U.S. population and leads to tremendous morbidity. Numerous nonsurgical and surgical treatments have been utilized to try and manage neuropathic pain with varying degrees of success. Recent research investigating ways to improve prosthetic control have identified new mechanisms for preventing neuromas in both motor and sensory nerves with free muscle and dermal grafts, respectively. These procedures have been used to treat chronic neuropathic pain in nonamputees, as well, in order to reduce failure rates found with traditional neurectomy procedures. Herein, we focus our attention on Dermal Sensory-Regenerative Peripheral Nerve Interfaces (DS-RPNI, free dermal grafts) which can be used to physiologically “cap” sensory nerves following neurectomy and have been shown to significantly decrease neuropathic pain.

神经病理性疼痛影响着美国很大一部分人口,并导致巨大的发病率。许多非手术和手术疗法都被用于治疗神经性疼痛,但都取得了不同程度的成功。最近对如何改善假肢控制的研究发现了新的机制,可以分别通过游离肌肉和真皮移植来预防运动神经和感觉神经的神经瘤。这些手术也被用于治疗非截肢者的慢性神经性疼痛,以降低传统神经切除术的失败率。在此,我们重点关注皮肤感觉-再生外周神经接口(DS-RPNI,游离真皮移植),它可用于神经切除术后的生理性感觉神经 "盖帽",并已被证明可显著减轻神经性疼痛。
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引用次数: 0
A History of Gender-Affirming Surgery at the University of Michigan: Lessons for Today 密歇根大学性别确认手术的历史:对今天的启示
IF 2 3区 医学 Q2 SURGERY Pub Date : 2024-01-19 DOI: 10.1055/s-0043-1778042
Cole Roblee, Os Keyes, Gaines Blasdel, Caleb Haley, Megan Lane, Lauren Marquette, Jessica Hsu, William M. Kuzon Jr.

The University of Michigan has played an important role in advancing gender-affirming surgery programs in the United States. The University of Michigan was home to a little-known gender identity clinic shortly after the opening of the first such clinic at Johns Hopkins. Since 1995, the University of Michigan Comprehensive Services Program (UMCGSP) has been continually offering surgical services to transgender and gender diverse patients. Here, we present the history of both programs, drawn from program documents and oral history, and explore their implications for the future sustainability of gender-affirming surgery programs. The original gender identity clinic opened in 1968, and operated in a multidisciplinary fashion, similar to other clinics at the time. Eventually, the clinic was closed due to disinvestment and lack of sufficient providers to maintain the program, problems which are being increasingly recognized as barriers for similar programs. The modern program, UMCGSP is perhaps the longest continually running gender-affirming surgical program at an academic center. In spite of challenges, key investments in education, statewide community engagement, and the development of a comprehensive care model have helped UMCGSP avoid the pitfalls of the earlier clinic and remain relevant throughout its nearly 30-year history. In the face of rising challenges to gender-affirming care in the United States, much can be learned from the sustainability of the UMCGSP. Institutions seeking to maintain gender-affirming surgery programs should ensure the availability of comprehensive care and promote the education of the health care workforce.

密歇根大学在推动美国性别确认手术项目方面发挥了重要作用。在约翰霍普金斯大学开设第一家性别认同诊所后不久,密歇根大学就开设了一家鲜为人知的性别认同诊所。自 1995 年以来,密歇根大学综合服务计划(UMCGSP)一直在为变性和性别多元化患者提供手术服务。在此,我们将从项目文件和口述历史中介绍这两个项目的历史,并探讨它们对性别确认手术项目未来可持续性的影响。最初的性别认同诊所于 1968 年开业,以多学科的方式运营,与当时的其他诊所类似。最终,由于投资减少和缺乏足够的医疗服务提供者来维持项目,该诊所关闭了,而这些问题正被越来越多的人认为是类似项目的障碍。作为一个现代项目,UMCGSP 可能是学术中心中持续开展时间最长的性别平等手术项目。尽管挑战重重,但在教育、全州社区参与和发展综合护理模式方面的关键投资,帮助 UMCGSP 避免了早期诊所的陷阱,并在近 30 年的历史中始终保持其相关性。面对美国性别平等医疗面临的日益严峻的挑战,我们可以从 UMCGSP 的可持续发展中学到很多东西。寻求维持性别平等手术项目的机构应确保提供全面的医疗服务,并促进医疗队伍的教育。
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引用次数: 0
A Historical Review of Racial, Ethnic, and Gender Diversity in Plastic Surgery at the University of Michigan 密歇根大学整形外科种族、民族和性别多样性的历史回顾
IF 2 3区 医学 Q2 SURGERY Pub Date : 2024-01-19 DOI: 10.1055/s-0043-1778044
Julien J.L. Levy, Rachel C. Hooper

In this article, we examine the 60-year history of diversity efforts within the Section of Plastic Surgery at the University of Michigan (UofM) in the context of national trends. We describe the experiences of pioneering Underrepresented in Medicine (URiM) and female graduates of the program. James Norris, MD, and Christine Sullivan, MD, were the first URiM and female graduates from UofM in 1974 and 1989, respectively. Currently, women constitute over one-half the plastic surgery trainees at UofM, but URiM trainee representation remains limited. Dr. Adeyiza Momoh and Dr. Amy Alderman were the first URiM and female faculty members hired in 2011 and 2004, respectively. At present, there are four URiM and seven female faculty members in the Section. With a shared vision, supportive leadership, and motivation to change, faculty diversity has increased substantially. Additional strategies, including ongoing pipeline programs in medicine and science for URiM and women, are needed to further increase workforce diversity in plastic surgery.

在这篇文章中,我们结合全国的发展趋势,回顾了密歇根大学整形外科 60 年来在多元化方面所做的努力。我们描述了医学界代表不足(URiM)的先驱和该专业女性毕业生的经历。医学博士詹姆斯-诺里斯(James Norris)和医学博士克里斯蒂娜-沙利文(Christine Sullivan)分别于 1974 年和 1989 年成为密歇根大学第一批URiM 和女性毕业生。目前,麻省理工大学整形外科受训人员中女性占一半以上,但URiM受训人员的比例仍然有限。阿德伊扎-莫莫(Adeyiza Momoh)博士和艾米-奥尔德曼(Amy Alderman)博士分别于2011年和2004年受聘成为URiM第一位女教员。目前,该科共有四名 URiM 教员和七名女教员。有了共同的愿景、支持性的领导和变革的动力,教职员工的多样性得到了大幅提高。要进一步提高整形外科劳动力的多样性,还需要采取其他策略,包括为URiM和女性持续开展医学和科学方面的管道计划。
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引用次数: 0
Pyrocarbon Lunate Arthroplasty: An Option for the Young Patient with Advanced Kienbock Disease 火碳月牙关节成形术:晚期基恩博克病年轻患者的一种选择
IF 2 3区 医学 Q2 SURGERY Pub Date : 2024-01-19 DOI: 10.1055/s-0043-1778036
Shashank S. Dwivedi, Kevin C. Chung

Kienbock disease, or avascular necrosis of the lunate, is an uncommon cause of a painful and stiff wrist. Management options range from conservative treatment in the form of immobilization and corticosteroid injections to a wide variety of surgical treatments that depend on the structural integrity of the lunate, intercarpal relationships, and the condition of the articular cartilage of the wrist. A particularly difficult problem lies in the management of young patient in whom vascularized bone grafting of the lunate has failed but in whom arthritis has not yet developed. Pyrocarbon lunate implant arthroplasty is a newer treatment option for such a patient, and allows the preservation of the remainder of the proximal carpal row while directly addressing the degenerative lunate. This article describes the evidence and surgical technique for lunate implant arthroplasty and presents an illustrative case example.

基恩博克病或月骨无血管性坏死是导致手腕疼痛和僵硬的一个不常见原因。治疗方法多种多样,从固定和注射皮质类固醇的保守治疗,到取决于月骨结构完整性、腕骨间关系和腕关节软骨状况的各种手术治疗。对于月骨血管移植失败但尚未发展成关节炎的年轻患者,如何治疗是一个特别棘手的问题。对于这类患者,碳化火烧月骨植入关节成形术是一种较新的治疗方案,它可以保留腕骨近端的其余部分,同时直接治疗退行性月骨。本文介绍了月骨植入关节成形术的证据和手术技巧,并提供了一个示例病例。
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引用次数: 0
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Seminars in Plastic Surgery
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