Anaesthesia Critical Care & Pain Medicine最新文献_第6页

Comparison of two different positions of an anaesthesiologist for ease of endotracheal intubation in adult patients: A randomised control trial 比较麻醉师的两种不同体位对成年患者气管插管的易用性：随机对照试验。

IF 3.7 3区医学 Q1 ANESTHESIOLOGY

Anaesthesia Critical Care & Pain Medicine

Pub Date : 2024-10-01 DOI: 10.1016/j.accpm.2024.101422

Poonam Kumari, Amarjeet Kumar, Chandni Sinha, Ajeet Kumar, Kunal Singh

Background and aims

Maintaining the airway with a cuffed endotracheal tube (ETT) in the trachea remains one of the most essential anaesthesia skills. Many parameters were described to assess the difficulty of intubation in the preoperative period, but none allow the prediction of all difficult intubations. The correct posture of the anaesthesiologist is also an important factor for successful endotracheal intubation. The aim of this study was. This study aimed to compare the impact of two different positions of an anaesthesiologist (sitting vs. standing) at the time of endotracheal intubation.

Methods

One hundred ten American Society of Anaesthesiologists (ASA) Physical Status I/II patients, aged between 17 to 65 years, Mallampati grade I/II, mouth opening 39–70 mm, thyromental distance (TMD) 6–6.5 cm, and sternomental distance (SMD) >13 cm, scheduled for elective laparoscopic cholecystectomy, were recruited. Patients were divided into two groups; Group I consisted of patients who underwent endotracheal intubation by an anaesthesiologist in a sitting posture, while Group II encompassed patients who underwent endotracheal intubation by anaesthesiologists in a standing posture. Assessment parameters include ease of intubation (IDS score), intubation time, intubation success rate, number of attempts, grade of laryngoscopy (Cormack Lehane score, POGO score), and complications like tooth and soft tissue damage.

Results

The ease of intubation was higher in group I, 1(0–1), than in group II, 1(1−2) (p = 0.02), and there was a significant difference between the two groups. The Cormack Lehane grade (CL) was I/IIa/IIb/III in 19/23/13/0 in group I and I/IIa/IIb/III in 13/21/18/3 in group II. The first-attempt intubation success rate for groups I and II was 94.54 % and 92.72 % respectively.

Conclusion

The sitting posture of an anaesthesiologist at the time of laryngoscopy provides a better intubating condition when compared with the standing posture.

Registration

Clinical Trial Registry - India (CTRI) CTRI/2023/03/050371.

背景和目的：在气管内使用带袖带的气管导管（ETT）保持气道通畅仍然是最基本的麻醉技能之一。许多参数被用来评估术前插管的难度，但没有一个参数可以预测所有困难插管。麻醉师的正确姿势也是成功进行气管插管的重要因素。本研究的目的是本研究旨在比较麻醉医师在气管插管时两种不同姿势（坐姿与站姿）的影响：方法：招募了 110 名美国麻醉医师协会（ASA）身体状况 I/II 级患者，年龄在 17 至 65 岁之间，Mallampati I/II 级，张口 39 至 70 毫米，甲状腺距离（TMD）6 至 6.5 厘米，胸骨距离（SMD）大于 13 厘米，计划进行择期腹腔镜胆囊切除术。患者被分为两组，第一组包括由麻醉师以坐姿进行气管插管的患者，第二组包括由麻醉师以站立姿势进行气管插管的患者。评估参数包括插管难易程度（IDS 评分）、插管时间、插管成功率、尝试次数、喉镜检查等级（Cormack Lehane 评分、POGO 评分）以及牙齿和软组织损伤等并发症：结果：第一组（1（0-1））的插管难易度高于第二组（1（1-2））（P = 0.02），两组之间存在显著差异。I 组中 19/23/13/0 的 Cormack Lehane 分级（CL）为 I/IIa/IIb/III，II 组中 13/21/18/3 的 Cormack Lehane 分级（CL）为 I/IIa/IIb/III。第一组和第二组的首次尝试插管成功率分别为 94.54 % 和 92.72 %：结论：与站立姿势相比，麻醉医生在喉镜检查时的坐姿能提供更好的插管条件：注册：印度临床试验注册中心（CTRI）CTRI/2023/03/050371。

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引用次数: 0

Methodological challenges in rapid molecular testing for pneumonia: Insights and future directions for performing “the perfect” study 肺炎快速分子检测的方法挑战：开展 "完美 "研究的启示和未来方向。

IF 3.7 3区医学 Q1 ANESTHESIOLOGY

Anaesthesia Critical Care & Pain Medicine

Pub Date : 2024-10-01 DOI: 10.1016/j.accpm.2024.101415

Antoni Torres , Laia Fernández-Barat

引用次数: 0

Combined hypoglossal and lingual nerve palsy: An unrecognized complication after orotracheal intubation for general anaesthesia. A case report of a day surgery patient and a literature review 舌下神经和舌神经联合麻痹：全身麻醉气管插管后一种未被发现的并发症。日间手术患者的病例报告和文献综述。

IF 3.7 3区医学 Q1 ANESTHESIOLOGY

Anaesthesia Critical Care & Pain Medicine

Pub Date : 2024-10-01 DOI: 10.1016/j.accpm.2024.101418

Laure Cazenave , Philippe Mahiou , John Swan , Philippe Clavert , Johannes Barth

Cranial nerve injury after orotracheal intubation is a rare complication, which has varied etiology. We present a case of combined unilateral hypoglossal and lingual nerve palsy after orotracheal intubation. The current literature was reviewed for the diagnostic, treatment, follow-up, and preventive measures of this complication.

气管插管后颅神经损伤是一种罕见的并发症，其病因多种多样。我们报告了一例气管插管后合并单侧舌下神经和舌神经麻痹的病例。我们查阅了现有文献，以了解该并发症的诊断、治疗、随访和预防措施。

引用次数: 0

Universal use of videolaryngoscope for all intubations in the ICU: The time is now! 在重症监护室的所有插管过程中普遍使用视频喉镜：时不我待！

IF 3.7 3区医学 Q1 ANESTHESIOLOGY

Anaesthesia Critical Care & Pain Medicine

Pub Date : 2024-10-01 DOI: 10.1016/j.accpm.2024.101417

Clément Monet , Philippe Richebé , Samir Jaber

引用次数: 0

High-flow nasal cannula and in-line aerosolised bronchodilator delivery during severe exacerbation of asthma in adults: a feasibility observational study 成人哮喘严重恶化期间的高流量鼻导管和在线气雾支气管扩张剂给药：可行性观察研究。

IF 3.7 3区医学 Q1 ANESTHESIOLOGY

Anaesthesia Critical Care & Pain Medicine

Pub Date : 2024-10-01 DOI: 10.1016/j.accpm.2024.101414

Nicolás Colaianni-Alfonso , Ada Toledo , Guillermo Montiel , Mauro Castro-Sayat , Claudia Crimi , Luigi Vetrugno

Background

Asthma is a common chronic respiratory disease affecting 1–29% of the population in different countries. Exacerbations represent a change in symptoms and lung function from the patient's usual condition that requires emergency department (ED) admission. Recently, the use of a High-Flow Nasal Cannula (HFNC) plus an in-line vibrating mesh nebulizer (VMN) for aerosol drug delivery has been advocated in clinical practice. Thus, this pilot observational study aims to investigate the feasibility of HFNC treatment with VMN for in-line bronchodilator delivery in patients with severe asthma.

Methods

This study was conducted from May 2022 to May 2023. Subjects ≥18 years old with a previous diagnosis of asthma who were admitted to the ED during severe exacerbation were included. The primary endpoint was the change in peak expiratory flow ratio (PEFR) after 2-h of treatment with bronchodilator delivered by HFNC with in-line VMN. Additional outcomes were changes in forced expiratory volume in 1 s (FEV₁) and clinical variables before treatment.

Results

30 patients, mean age of 43 (SD ± 16) years, mostly female (67%) were studied. A significant change in PEFR (147 ± 31 L/m vs. 220 ± 38 L/m; p < 0.001) was observed after treatment with HFNC and in-line VMN with significant improvement in clinical variables. And no subjects required invasive mechanical ventilation (IMV) during the study.

Conclusions

HFNC treatment with in-line VMN for bronchodilator delivery appears feasible and safe for patients with severe asthma exacerbation. These preliminary promising results should be confirmed with appropriately large-designed studies.

背景：哮喘是一种常见的慢性呼吸道疾病，在不同国家影响着 1-29% 的人口。哮喘加重意味着患者的症状和肺功能与往常不同，需要入住急诊科（ED）。最近，临床实践中提倡使用高流量鼻导管（HFNC）和在线振动网状雾化器（VMN）进行气溶胶给药。因此，本试验性观察研究旨在调查 HFNC 治疗与 VMN 用于重症哮喘患者在线支气管扩张剂给药的可行性：本研究于 2022 年 5 月至 2023 年 5 月进行。研究对象包括年龄≥ 18 岁、既往诊断为哮喘且在严重哮喘加重期间入住急诊室的患者。主要终点是在使用带有线控 VMN 的 HFNC 支气管扩张剂治疗 2 小时后呼气峰值流量比 (PEFR) 的变化。其他结果包括 1 秒用力呼气容积（FEV1）的变化和治疗前的临床变量：研究的 30 名患者平均年龄为 43 岁（SD ± 16），大部分为女性（67%）。PEFR 有明显变化（147 ± 31 L/m vs. 220 ± 38 L/m；p 结论：治疗前，PEFR 有明显变化（147 ± 31 L/m vs. 220 ± 38 L/m；p）：对于严重哮喘加重的患者来说，使用线控 VMN 输送支气管扩张剂的高频数控治疗似乎是可行和安全的。这些初步的良好结果应通过适当的大型设计研究加以证实。

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引用次数: 0

Postoperative Pain Management in children: guidance from the Pain Committee of the European Society for Paediatric Anaesthesiology (ESPA Pain Management Ladder Initiative) Part II 儿童术后疼痛管理：欧洲儿科麻醉学会疼痛委员会指南（ESPA 疼痛管理阶梯倡议）第二部分。

IF 3.7 3区医学 Q1 ANESTHESIOLOGY

Anaesthesia Critical Care & Pain Medicine

Pub Date : 2024-09-17 DOI: 10.1016/j.accpm.2024.101427

Maria Vittinghoff , Per Arne Lönnqvist , Valeria Mossetti , Stefan Heschl , Dusica Simic , Vesna Colovic , Martin Hözle , Marzena Zielinska , Belen De Josè Maria , Francesca Oppitz , Diana Butkovic , Neil S. Morton

The ESPA Pain Management Ladder Initiative is a clinical practice advisory based upon expert consensus supported by the current literature to help ensure a basic standard of perioperative pain management for all children. In 2018 the perioperative pain management of six common pediatric surgical procedures was summarised. The current Pain Management Ladder recommendations focus on five more complex pediatric surgical procedures and suggest basic, intermediate, and advanced pain management methods. The aim of this paper is to encourage best possible pain management practice and to support institutions to create their own pain management concepts according to their financial and human resources due to the diversity of clinical settings in Europe. Furthermore, the authors underline that these recommendations are intended for inpatients only.

ESPA疼痛管理阶梯计划是一项基于专家共识的临床实践建议，得到了当前文献的支持，有助于确保所有儿童围手术期疼痛管理的基本标准。2018 年，对六种常见儿科外科手术的围手术期疼痛管理进行了总结。目前的疼痛管理阶梯建议主要针对五种更复杂的儿科外科手术，并提出了基本、中级和高级疼痛管理方法。由于欧洲临床环境的多样性，本文旨在鼓励尽可能最佳的疼痛管理实践，并支持医疗机构根据其财力和人力资源创建自己的疼痛管理理念。此外，作者强调这些建议仅适用于住院患者。

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引用次数: 0

Effects of dexmedetomidine versus propofol on outcomes in critically ill patients with different sedation depths: a propensity score-weighted cohort study 右美托咪定与异丙酚对不同镇静深度重症患者预后的影响：倾向得分加权队列研究。

IF 3.7 3区医学 Q1 ANESTHESIOLOGY

Anaesthesia Critical Care & Pain Medicine

Pub Date : 2024-09-16 DOI: 10.1016/j.accpm.2024.101425

Hao-Chin Wang , Chun-Jen Huang , Shu-Fen Liao , Ru-Ping Lee

Objective

We explored the effects of dexmedetomidine (DEX) versus propofol on outcomes in critically ill patients and to assess whether these effects are dissimilar under different sedation depths.

Methods

A stabilized inverse probability of treatment weighting cohort study was conducted using data from the Medical Information Mart for Intensive Care IV database from 2008 to 2019. Adult intensive care unit (ICU) patients who were administered DEX or propofol as the primary sedative were identified. Various statistical methods were used to evaluate the effects of DEX versus propofol on outcomes.

Results

Data on 107 and 2318 patients in DEX and propofol groups, respectively, were analyzed. Compared to the propofol group, the DEX group exhibited longer ventilator-free days on day 28 and a shorter ICU stay. Conversely, it showed null associations of DEX with the risk of 90-day ICU mortality, the odds of persistent organ dysfunction on day 14 and acute kidney injury, and the duration of vasopressor-free days on day 28. Subgroup analyses revealed that DEX positively impacted persistent organ dysfunction on day 14, ventilator-free days on day 28, and ICU stay in the subgroup with a Richmond Agitation Sedation Scale (RASS) score of ≥−2. However, DEX negatively impacted 90-day ICU mortality, persistent organ dysfunction on day 14, and ventilator-free days on day 28 in the subgroup with a RASS score of <−2.

Conclusion

Our results indicated that, compared with propofol, DEX had beneficial and adverse impacts on certain ICU outcomes in critically ill patients, and these impacts appeared to depend on sedation depths.

目的我们探讨了右美托咪定（DEX）与丙泊酚对重症患者预后的影响，并评估这些影响在不同镇静深度下是否不同。方法利用2008年至2019年重症监护医学信息市场IV数据库的数据，开展了一项稳定的逆概率治疗加权队列研究。研究确定了使用DEX或丙泊酚作为主要镇静剂的成人重症监护病房（ICU）患者。结果分析了DEX组和丙泊酚组分别为107例和2318例患者的数据。与异丙酚组相比，DEX 组第 28 天无呼吸机天数更长，重症监护室住院时间更短。相反，DEX与重症监护室90天死亡风险、第14天持续器官功能障碍和急性肾损伤的几率以及第28天无呼吸机天数的持续时间呈负相关。亚组分析显示，在里士满躁动镇静量表（RASS）评分≥-2的亚组中，DEX对第14天持续器官功能障碍、第28天无呼吸机天数和ICU住院时间有积极影响。结论我们的研究结果表明，与异丙酚相比，DEX对重症患者的某些ICU预后既有有利影响，也有不利影响，这些影响似乎取决于镇静深度。

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引用次数: 0

Prophylactic application of dexmedetomidine reduces the incidence of emergence delirium in children: A systematic review and meta-analysis 预防性使用右美托咪定可降低儿童出现谵妄的几率：系统回顾与元分析。

IF 3.7 3区医学 Q1 ANESTHESIOLOGY

Anaesthesia Critical Care & Pain Medicine

Pub Date : 2024-09-16 DOI: 10.1016/j.accpm.2024.101426

Sai-hao Fu , Meng-rong Miao , Lu-yao Zhang , Jing Bian , Yun-xiang Fu , Jia-qiang Zhang , Ming-yang Sun

Background

Emergence delirium (ED) is a common postoperative cognitive dysfunction in children. ED may cause distress to patients and their families in the early post-anesthesia period and have long-term adverse effects on children.

The primary purpose

was to verify whether dexmedetomidine can reduce the occurrence of ED in children.

Research type

Systematic review and meta-analysis of RCTs.

Data acquisition

A search was conducted on Web of Science, WHO Trials, Cochrane Library, Clinical Trials.gov, and PubMed for all published studies from inception to 23 Oct. 2022.

Eligibility criteria

Randomized clinical trials that met the following criteria: patients aged 1–18 years, study site in the PACU (Post-anesthesia care unit), incidence of ED as the primary outcome, and prophylactic use of dexmedetomidine defined as injected before admission to the PACU.

Results

A total of 7 randomized trials were included (6 studies during eye and neck surgery, 1 during hernia surgery), involving 512 patients (257 (50.1%) with dexmedetomidine, and 250 (49.9%) with control. ED was observed in 17.51% of the patients treated with dexmedetomidine and in 43.14% of those receiving control (risk ratio (RR) = 0.40, 95 % confidence interval [CI] [0.30−0.55], P < 0.00001). Additionally, the prophylactic application of dexmedetomidine also reduced the occurrence of Post-Operating Nausea and Vomiting (RR = 0.24, 95%CI [0.12−0.49], P = 0.0001) and PACU stay time after extubation (mean difference (MD) = −1.57, 95%CI [−3.07 to −0.07], P = 0.04). However, sensitivity analysis of RCTs showed that our effect estimates were not stable (MD = −1.78, 95%CI [−4.18−0.62], P = 0.15).

Conclusion

The prophylactic use of dexmedetomidine was associated with a reduction of ED. However, our findings only apply to eye and neck surgery.

Trial registration

PROSPERO: CRD42022371840.

背景谵妄（ED）是儿童术后常见的认知功能障碍。ED 可能会在麻醉后早期对患者及其家属造成困扰，并对儿童产生长期不良影响。研究类型系统综述和荟萃分析 RCTs.DATA ACQUISITION在 Web of Science、WHO Trials、Cochrane Library、Clinical Trials.gov 和 PubMed 上搜索了从开始到 2022 年 10 月 23 日发表的所有研究。.筛选标准符合以下标准的随机临床试验：患者年龄在 1-18 岁之间，研究地点在 PACU（麻醉后护理病房），ED 发生率为主要结果，预防性使用右美托咪定的定义是在进入 PACU 之前注射。结果共纳入了 7 项随机试验（6 项在眼部和颈部手术中进行，1 项在疝气手术中进行），涉及 512 名患者（257 人（50.1%）使用右美托咪定，250 人（49.9%）使用对照组。在使用右美托咪定的患者中，17.51%的患者出现了ED，而在使用对照组的患者中，43.14%的患者出现了ED（风险比（RR）= 0.40，95%置信区间[CI] [0.30 - 0.55]，P < 0.00001）。此外，预防性应用右美托咪定还减少了术后恶心和呕吐的发生率（RR = 0.24，95% 置信区间 [0.12 - 0.49]，P = 0.0001）和拔管后在 PACU 的停留时间（平均差 (MD) =-1.57，95% 置信区间 [-3.07 to -0.07]，P = 0.04）。结论预防性使用右美托咪定可减少 ED。然而，我们的研究结果仅适用于眼部和颈部手术。

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引用次数: 0

Integrating StEP-COMPAC definition and enhanced recovery after surgery status in a machine-learning-based model for postoperative pulmonary complications in laparoscopic hepatectomy 基于机器学习的腹腔镜肝切除术术后肺部并发症模型整合了 StEP-COMPAC 定义和术后增强恢复状态。

IF 3.7 3区医学 Q1 ANESTHESIOLOGY

Anaesthesia Critical Care & Pain Medicine

Pub Date : 2024-09-13 DOI: 10.1016/j.accpm.2024.101424

Sibei Li , Yaxin Lu , Hong Zhang , Chuzhou Ma , Han Xiao , Zifeng Liu , Shaoli Zhou , Chaojin Chen

Background

Postoperative pulmonary complications (PPCs) contribute to high mortality rates and impose significant financial burdens. In this study, a machine learning-based prediction model was developed to identify patients at high risk of developing PPCs following laparoscopic hepatectomy.

Methods

Data were collected from 1022 adult patients who underwent laparoscopic hepatectomy at two centres between January 2015 and February 2021. The dataset was divided into a development set and a temporal external validation set based on the year of surgery. A total of 42 factors were extracted for pre-modelling, including the implementation status of Enhanced Recovery after Surgery (ERAS). Feature selection was performed using the least absolute shrinkage and selection operator (LASSO) method. Model performance was assessed using the area under the receiver operating characteristic curve (AUC). The model with the best performance was externally validated using temporal data.

Results

The incidence of PPCs was 8.7%. Lambda.1se was selected as the optimal lambda for LASSO feature selection. For implementation of ERAS, serum gamma-glutamyl transferase levels, malignant tumour presence, total bilirubin levels, and age-adjusted Charleston Comorbidities Index were the selected factors. Seven models were developed. Among them, logistic regression demonstrated the best performance, with an AUC of 0.745 in the internal validation set and 0.680 in the temporal external validation set.

Conclusions

Based on the most recent definition, a machine learning model was employed to predict the risk of PPCs following laparoscopic hepatectomy. Logistic regression was identified as the best-performing model. ERAS implementation was associated with a reduction in the number of PPCs.

背景：术后肺部并发症（PPCs）会导致高死亡率，并造成巨大的经济负担。本研究开发了一种基于机器学习的预测模型，用于识别腹腔镜肝切除术后出现肺并发症的高风险患者：方法：收集了2015年1月至2022年2月期间在两个中心接受腹腔镜肝切除术的1022名成年患者的数据。数据集根据手术年份分为开发集和时间外部验证集。共提取了 42 个因素进行预建模，其中包括术后增强恢复（ERAS）的实施状态。特征选择采用最小绝对收缩和选择算子（LASSO）方法。使用接收者工作特征曲线下面积（AUC）评估模型性能。利用时间数据对性能最佳的模型进行了外部验证：结果：PPC 的发病率为 8.7%。Lambda.1se 被选为 LASSO 特征选择的最佳 lambda。在实施ERAS时，血清γ-谷氨酰转移酶水平、是否存在恶性肿瘤、总胆红素水平和经年龄调整的Charleston合并症指数是选定的因素。共建立了七个模型。其中，逻辑回归表现最佳，内部验证集的AUC为0.745，临时外部验证集的AUC为0.680：结论：根据最新的定义，采用机器学习模型预测腹腔镜肝切除术后发生 PPCs 的风险。逻辑回归被认为是效果最好的模型。ERAS的实施与PPCs数量的减少有关。

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引用次数: 0

Effect of ventilation mode on postoperative pulmonary complications among intermediate- to high-risk patients undergoing abdominal surgery: A randomized controlled trial 通气模式对腹部手术中高危患者术后肺部并发症的影响：随机对照试验。

IF 3.7 3区医学 Q1 ANESTHESIOLOGY

Anaesthesia Critical Care & Pain Medicine

Pub Date : 2024-09-13 DOI: 10.1016/j.accpm.2024.101423

Xuefei Li , Yi Xu , Zaili Wang , Weiwei Wang , Qiansu Luo , Qianglin Yi , Hai Yu

Background

The effect of different mechanical ventilation modes on pulmonary outcome after abdominal surgery remains unclear. We evaluated the effects of three common ventilation modes on postoperative pulmonary complications (PPCs) among intermediate- to high-risk patients undergoing abdominal surgery.

Methods

This randomized clinical trial enrolled adult patients at intermediate or high risk of PPCs who were scheduled for abdominal surgery. Participants were randomized to receive one of three modes of mechanical ventilation modes: volume-controlled ventilation (VCV), pressure-controlled ventilation (PCV), and pressure-control with volume-guaranteed ventilation (PCV-VG). Lung-protective ventilation strategy was implemented in all groups. The primary outcome was the incidence of a composite of pulmonary complications within the first 7 postoperative days. Pulmonary complications within 30 postoperative days, the severity grade of PPCs, and other secondary outcomes were also analyzed.

Results

A total of 1365 patients were randomized and 1349 were analyzed. The primary outcome occurred in 98 (21.8%) in the VCV group, 95 (22.1%) in the PCV group, and 101 (22.5%) in the PCV-VG group (P = 0.865). Additionally, there were no statistically significant differences among the three groups in terms of the incidence of pulmonary complications within postoperative 30 days, severity grade of PPCs, and other secondary outcomes.

Conclusion

In intermediate- to high-risk patients undergoing abdominal surgery, the choice of ventilation mode did not affect the risk of PPCs.

Trial Registration

Chinese Clinical Trial Registry, entry ChiCTR1900025880.

背景：不同的机械通气模式对腹部手术后肺部预后的影响仍不明确。我们评估了三种常见通气模式对腹部手术中高危患者术后肺部并发症（PPCs）的影响：这项随机临床试验招募了计划接受腹部手术的中高危成人患者。参与者被随机分配接受三种机械通气模式中的一种：容量控制通气（VCV）、压力控制通气（PCV）和带容量保证的压力控制通气（PCV-VG）。所有组别均采用肺保护通气策略。主要结果是术后 7 天内肺部并发症的综合发生率。此外，还分析了术后 30 天内的肺部并发症、PPCs 的严重程度等级以及其他次要结果：共有 1365 名患者接受了随机治疗，其中 1349 人接受了分析。VCV 组有 98 例（21.8%）、PCV 组有 95 例（22.1%）、PCV-VG 组有 101 例（22.5%）出现主要结局（P = 0.865）。此外，在术后 30 天内肺部并发症的发生率、PPCs 的严重程度等级以及其他次要结果方面，三组之间没有显著的统计学差异：结论：对于接受腹部手术的中高危患者，通气模式的选择不会影响PPCs的风险：试验注册：中国临床试验注册中心，注册号：ChiCTR1900025880。

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引用次数: 0