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Journal of Translational Medicine & Transplantation Research最新文献

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Investigation of Regenerative Effects of Theranekron® and Misoprostol after Partial Hepatectomy in Rats Theranekron®和米索前列醇对大鼠肝部分切除后再生作用的研究
Pub Date : 2023-09-30 DOI: 10.47363/jtmtr/2023(2)109
İsmet Yılmaz, Burhan Hakan Kanat, Azibe Yildiz
In the present study we were aimed to investigate/compare regenerative effects of Theranekron® (TC) and Misoprostol (MS) after Partial Hepatectomy (PH) in rats. This study was conducted in 38 rats, they were divided in to 5 groups and 7 days study periot. When considering biochemical and histopathological results; we were seen that after PH 7 days duration was not sufficient and also at least 10 days periot may be necessary. Although some literatures were reported about positive effects of TC and MS on epithelial growing, we have not seen that they have not any positive effect on liver regeneration. In the future -at different doses and durations- these may be found effective.
在本研究中,我们旨在研究/比较Theranekron®(TC)和米索前列醇(MS)在大鼠肝部分切除术(PH)后的再生效果。实验选用大鼠38只,随机分为5组,每组7 d。在考虑生化和组织病理学结果时;我们看到,PH后7天的时间是不够的,至少10天的时间可能是必要的。虽然一些文献报道了TC和MS对上皮细胞生长的积极作用,但我们还没有看到它们对肝脏再生没有任何积极作用。将来,在不同的剂量和持续时间下,这些可能会被发现是有效的。
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Journal of Translational Medicine & Transplantation Research
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