Pub Date : 2024-05-23DOI: 10.56557/bn/2024/v44i12034
Ha-Bin Kim, Hyun-Joon Yoon, Dae-Kwang Kim
Intelligence has a huge influences and is very closely related with human’s life. Because intelligence is indefinable, scholars have specified it through testing tools and named it intelligence quotient (IQ). In measuring IQ, researchers have found that IQ has a wide distribution and tried to find out the reasons by assessing the brain's functional level and environmental and genetic factors. One study reported an association between IQ and mitochondrial DNA (mtDNA) sequence 15,925, and this study investigated the association in Koreans. The number of participants was 57 in the mental retardation group without chromosomal abnormalities and 148 in the normal group, respectively. PCR technique and direct sequencing analysis were used to know participant’s mtDNA sequences. At 15,925 base, all participants had only wild type C and no variant type of m.15,925 C > T. We further studied variants in mtDNA sequences 15,926-15,927. At 15,926 base, the variant type of 15,926 C < T was found in only one case (0.7%) in the control group. At the 15,927 base, variant type of 15,927 G < A was found in 9 cases (6.1%) in the control group and 1 case (1.8%) in the retardation group, respectively. As a result, the polymorphisms of mtDNA sequences at bases 15,925-15,927 had no statistical significance in the Korean control and mental retardation group.
智力影响巨大，与人的一生息息相关。由于智力无法定义，学者们通过测试工具对其进行了明确，并将其命名为智商（IQ）。在测量智商的过程中，研究人员发现智商有广泛的分布，并试图通过评估大脑的功能水平以及环境和遗传因素来找出原因。一项研究报告称，智商与线粒体 DNA（mtDNA）序列 15 925 之间存在关联。没有染色体异常的智力迟钝组和正常组的参与人数分别为 57 人和 148 人。研究人员采用聚合酶链反应（PCR）技术和直接测序分析法了解参与者的 mtDNA 序列。我们进一步研究了 mtDNA 序列 15,926-15,927 的变异。在 15,926 碱基上，对照组中只有一个病例（0.7%）发现了 15,926 C < T 的变异类型。在 15,927 碱基上，对照组有 9 例（6.1%）发现 15,927 G < A 的变异类型，弱智组有 1 例（1.8%）发现 15,927 G < A 的变异类型。因此，韩国对照组和智力迟钝组的 mtDNA 序列在 15,925-15,927 碱基上的多态性没有统计学意义。
{"title":"The Relationship between Intelligence and Mitochondrial DNA Polymorphism at Site of 15925 Base Pairs","authors":"Ha-Bin Kim, Hyun-Joon Yoon, Dae-Kwang Kim","doi":"10.56557/bn/2024/v44i12034","DOIUrl":"https://doi.org/10.56557/bn/2024/v44i12034","url":null,"abstract":"Intelligence has a huge influences and is very closely related with human’s life. Because intelligence is indefinable, scholars have specified it through testing tools and named it intelligence quotient (IQ). In measuring IQ, researchers have found that IQ has a wide distribution and tried to find out the reasons by assessing the brain's functional level and environmental and genetic factors. One study reported an association between IQ and mitochondrial DNA (mtDNA) sequence 15,925, and this study investigated the association in Koreans. The number of participants was 57 in the mental retardation group without chromosomal abnormalities and 148 in the normal group, respectively. PCR technique and direct sequencing analysis were used to know participant’s mtDNA sequences. At 15,925 base, all participants had only wild type C and no variant type of m.15,925 C > T. We further studied variants in mtDNA sequences 15,926-15,927. At 15,926 base, the variant type of 15,926 C < T was found in only one case (0.7%) in the control group. At the 15,927 base, variant type of 15,927 G < A was found in 9 cases (6.1%) in the control group and 1 case (1.8%) in the retardation group, respectively. As a result, the polymorphisms of mtDNA sequences at bases 15,925-15,927 had no statistical significance in the Korean control and mental retardation group.","PeriodicalId":490896,"journal":{"name":"BIONATURE","volume":"113 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141105957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-15DOI: 10.56557/bn/2024/v44i12031
Ezenwelu, Chijioke, O., Okeke, Chisom M., Udemezue, Onyeka, I., Ngwu, Ogochukwu, R., Oparaji, Emeka, H.
In the study, soil samples were impacted with 10%, 50% and 100% (v/w) of the palm oil mill effluents. Soil physicochemical properties, soil stress marker enzymes, soil bacteria populations were studied using standard methods. Analysis of the physicochemical properties of the Palm oil mill effluent (POME) showed that POME in the presence of the reference showed the following: pH, conductivity, BOD5, TDS, TSS, TS at 5.67 ±0.014a , 610±0.023c , 4.87±0.025b, 372.1±0.015c , 539.55±0.04a, 911.6±0.032b mg/ml, respectively dissolved mineral such as Magnessium (Mg), potassium (K), calcium (Ca) and phosphate (PO3) were recorded at 9.82±0.05b , 14.52±0.05a, 13.23±0.04c and 8.69±0.01bc mg/ml respectively. Total organic carbon and organic matter contents were recorded at 81.87±0.01a and 100.7±0.02c mg/ml respectively. Organismal proliferation increase as the percentage of the POME per gram of the soil increase from 10-50% (v/w) while a downturn in the organismal counts decreases significantly at 100% (v/w). There was a noticeable decrease in the coliform counts/g of the organisms as the incubation days increases from day 0-14. Enzyme activity relatively decreases as the contaminant concentrations increases from 0-100 v/w. Lipases activity was seen relatively low in all the soil at low concentrations of the effluents (0-50 v/w). At high concentrations of the effluents, there was a significant increase in the enzyme activity. POME can be utilized as sustainable source of organic agro fertilizer when quantified; however poor incentive by peasant farmers may lead to abysmal utilization of the waste water and its negative impact in the soil with aftermath of low soil fertility and poor agricultural productivity.
{"title":"Palm Oil Mill Effluent Disposal and Its Utilization in Agricultural Soil","authors":"Ezenwelu, Chijioke, O., Okeke, Chisom M., Udemezue, Onyeka, I., Ngwu, Ogochukwu, R., Oparaji, Emeka, H.","doi":"10.56557/bn/2024/v44i12031","DOIUrl":"https://doi.org/10.56557/bn/2024/v44i12031","url":null,"abstract":"In the study, soil samples were impacted with 10%, 50% and 100% (v/w) of the palm oil mill effluents. Soil physicochemical properties, soil stress marker enzymes, soil bacteria populations were studied using standard methods. Analysis of the physicochemical properties of the Palm oil mill effluent (POME) showed that POME in the presence of the reference showed the following: pH, conductivity, BOD5, TDS, TSS, TS at 5.67 ±0.014a , 610±0.023c , 4.87±0.025b, 372.1±0.015c , 539.55±0.04a, 911.6±0.032b mg/ml, respectively dissolved mineral such as Magnessium (Mg), potassium (K), calcium (Ca) and phosphate (PO3) were recorded at 9.82±0.05b , 14.52±0.05a, 13.23±0.04c and 8.69±0.01bc mg/ml respectively. Total organic carbon and organic matter contents were recorded at 81.87±0.01a and 100.7±0.02c mg/ml respectively. Organismal proliferation increase as the percentage of the POME per gram of the soil increase from 10-50% (v/w) while a downturn in the organismal counts decreases significantly at 100% (v/w). There was a noticeable decrease in the coliform counts/g of the organisms as the incubation days increases from day 0-14. Enzyme activity relatively decreases as the contaminant concentrations increases from 0-100 v/w. Lipases activity was seen relatively low in all the soil at low concentrations of the effluents (0-50 v/w). At high concentrations of the effluents, there was a significant increase in the enzyme activity. POME can be utilized as sustainable source of organic agro fertilizer when quantified; however poor incentive by peasant farmers may lead to abysmal utilization of the waste water and its negative impact in the soil with aftermath of low soil fertility and poor agricultural productivity.","PeriodicalId":490896,"journal":{"name":"BIONATURE","volume":"56 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140973912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-16DOI: 10.56557/bn/2024/v44i12013
Tejaswini S Dhamdar, Sandhya K V, B. V. Basavaraj
The integration of biomimicry principles with artificial intelligence (AI) presents a compelling approach to addressing complex challenges across various domains. This article explores the synergy between biomimicry and AI, elucidating how the emulation of natural processes and structures can inspire innovative solutions. Beginning with an overview of biomimicry's historical roots and notable achievements, the narrative progresses to highlight AI's role in accelerating biomimetic research and innovation. Various applications of biomimicry, ranging from material development to biotech and climate change mitigation, are discussed, showcasing the breadth of possibilities offered by this interdisciplinary approach. Challenges and ethical considerations inherent in combining biomimicry and AI were also examined, emphasizing the need for multidisciplinary collaboration and ethical awareness. Looking ahead, future directions in research are outlined, including the development of AI algorithms that integrate knowledge from diverse biological sources and the incorporation of moral considerations into biomimetic design processes. Ultimately, the article concludes by suggesting that the convergence of biomimicry and AI holds promise for fostering sustainable, efficient, and ethically informed technological advancements, facilitating a harmonious relationship between humanity and the natural world. GRAPHICAL ABSTRACT:
{"title":"Advancing Innovation through Biomimicry and AI: Inspiration to Implementation","authors":"Tejaswini S Dhamdar, Sandhya K V, B. V. Basavaraj","doi":"10.56557/bn/2024/v44i12013","DOIUrl":"https://doi.org/10.56557/bn/2024/v44i12013","url":null,"abstract":"The integration of biomimicry principles with artificial intelligence (AI) presents a compelling approach to addressing complex challenges across various domains. This article explores the synergy between biomimicry and AI, elucidating how the emulation of natural processes and structures can inspire innovative solutions. Beginning with an overview of biomimicry's historical roots and notable achievements, the narrative progresses to highlight AI's role in accelerating biomimetic research and innovation. Various applications of biomimicry, ranging from material development to biotech and climate change mitigation, are discussed, showcasing the breadth of possibilities offered by this interdisciplinary approach. Challenges and ethical considerations inherent in combining biomimicry and AI were also examined, emphasizing the need for multidisciplinary collaboration and ethical awareness. Looking ahead, future directions in research are outlined, including the development of AI algorithms that integrate knowledge from diverse biological sources and the incorporation of moral considerations into biomimetic design processes. Ultimately, the article concludes by suggesting that the convergence of biomimicry and AI holds promise for fostering sustainable, efficient, and ethically informed technological advancements, facilitating a harmonious relationship between humanity and the natural world.\u0000GRAPHICAL ABSTRACT:","PeriodicalId":490896,"journal":{"name":"BIONATURE","volume":"32 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140696737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-26DOI: 10.56557/bn/2024/v44i11983
Jin-WonPark
Changes in the behavior of the prepared lipid bilayer according to each phase of the layer, induced by mucin incorporation, were investigated. 8-Aminonaphtalene-1,3,6-trisulfonic acid disodium salt (ANTS) was encapsulated only in the water-soluble interior of the vesicle. p-xylene-bis(N-pyridinium bromide) (DPX) settled only outside of the vesicles to quench the ANTS. The calibration was established for the fluorescence with the encapsulated ANTS separated from the DPX (100%) and the ANTS mixed with DPX (0%). The changes were found due to the layer phase over the ratio of mucin to lipid. The changes are determined by the stability of the vesicles.
研究了在加入粘蛋白的诱导下，所制备的脂质双分子层各阶段的行为变化。8-氨基萘-1,3,6-三磺酸二钠盐（ANTS）只被包裹在囊泡的水溶性内部，对二亚甲苯双（N-吡啶溴化物）（DPX）只沉淀在囊泡外部以淬灭 ANTS。在封装的 ANTS 与 DPX 分离（100%）和 ANTS 与 DPX 混合（0%）的情况下，对荧光进行了校准。发现变化是由于层相随粘蛋白和脂质的比例变化而产生的。这些变化取决于囊泡的稳定性。
{"title":"Exploring the Influence of Mucin on Lipid Bilayers: Insights into Phase-Dependent Interactions","authors":"Jin-WonPark","doi":"10.56557/bn/2024/v44i11983","DOIUrl":"https://doi.org/10.56557/bn/2024/v44i11983","url":null,"abstract":"Changes in the behavior of the prepared lipid bilayer according to each phase of the layer, induced by mucin incorporation, were investigated. 8-Aminonaphtalene-1,3,6-trisulfonic acid disodium salt (ANTS) was encapsulated only in the water-soluble interior of the vesicle. p-xylene-bis(N-pyridinium bromide) (DPX) settled only outside of the vesicles to quench the ANTS. The calibration was established for the fluorescence with the encapsulated ANTS separated from the DPX (100%) and the ANTS mixed with DPX (0%). The changes were found due to the layer phase over the ratio of mucin to lipid. The changes are determined by the stability of the vesicles.","PeriodicalId":490896,"journal":{"name":"BIONATURE","volume":"11 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140378588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-15DOI: 10.56557/bn/2024/v44i11971
Kajal
The majority of Indian homes include tulsi, often known as holy basil (Ocimum sanctum L). Although it is regarded as a spiritual plant, physiologically speaking, it is one of the most readily available antibiotics. Tulsi is the most significant herb in Ayurveda, and current research is confirming its health advantages. It is also one of the plants that are utilised widely in Ayurvedic treatments.It relieves physical, physiological, metabolic, and psychological stress due to its special mix of pharmacological activity. A substrate for the quick development and multiplication of commercially significant plants is provided by plant tissue culture. Determining the optimal explants type and medium conditions for large-scale in vitro Tulsi shoot induction is the aim of the current effort. In the current investigation, the nodal segment and shoot tips were employed as explants. The nodal segment reacted well with a frequency rate of about 90% on all MS media utilized in the current investigation, including media with BAP and media with different combinations of BAP and IAA. It was seen that one or more shoots were emerging from the explants' nodal area after 10 days of culture. In this work, we examined the effects of various PGR combinations and dosages on the in vitro micro propagation of Tulsi, a fragrant and therapeutic plant (Ocmium sanctum L.). Three distinct PGRs were utilized, namely 6-benzylaminopurine (BAP), naphthalene acetic acid (NAA), and indole-3-acetic acid (IAA). The optimal medium for inducing and multiplying shoots was found to be Murashige and Skoog (MS) medium supplemented with 0.25 mg/l BAP and 0.1 mg/l NAA. The MS medium exhibits average shoot formation with 0.025 mg/l IAA and 0.1 mg/l BAP. Our results demonstrate that Tulsi may be successfully micro-propagated in vitro with the appropriate PGR.
{"title":"In vitro Propagation of Ocimum Sanctum Linn by Using Growth Hormone Shoot Induction","authors":"Kajal","doi":"10.56557/bn/2024/v44i11971","DOIUrl":"https://doi.org/10.56557/bn/2024/v44i11971","url":null,"abstract":"The majority of Indian homes include tulsi, often known as holy basil (Ocimum sanctum L). Although it is regarded as a spiritual plant, physiologically speaking, it is one of the most readily available antibiotics. Tulsi is the most significant herb in Ayurveda, and current research is confirming its health advantages. It is also one of the plants that are utilised widely in Ayurvedic treatments.It relieves physical, physiological, metabolic, and psychological stress due to its special mix of pharmacological activity. A substrate for the quick development and multiplication of commercially significant plants is provided by plant tissue culture. Determining the optimal explants type and medium conditions for large-scale in vitro Tulsi shoot induction is the aim of the current effort. In the current investigation, the nodal segment and shoot tips were employed as explants. The nodal segment reacted well with a frequency rate of about 90% on all MS media utilized in the current investigation, including media with BAP and media with different combinations of BAP and IAA. It was seen that one or more shoots were emerging from the explants' nodal area after 10 days of culture. In this work, we examined the effects of various PGR combinations and dosages on the in vitro micro propagation of Tulsi, a fragrant and therapeutic plant (Ocmium sanctum L.). Three distinct PGRs were utilized, namely 6-benzylaminopurine (BAP), naphthalene acetic acid (NAA), and indole-3-acetic acid (IAA). The optimal medium for inducing and multiplying shoots was found to be Murashige and Skoog (MS) medium supplemented with 0.25 mg/l BAP and 0.1 mg/l NAA. The MS medium exhibits average shoot formation with 0.025 mg/l IAA and 0.1 mg/l BAP. Our results demonstrate that Tulsi may be successfully micro-propagated in vitro with the appropriate PGR.","PeriodicalId":490896,"journal":{"name":"BIONATURE","volume":"48 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140507562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-09DOI: 10.56557/bn/2023/v43i21877
P. Ashoka, G. J. Avinash, M. T. Apoorva, Pranav Raj, M. Sekhar, Sanjay Singh, R. Vijay Kumar, Bal veer Singh
Exploring the use of intelligent approaches, particularly artificial intelligence (AI) and machine learning (ML), in detecting soil nutrient deficiencies, is a crucial aspect of agriculture. Traditional methods of soil nutrient analysis, although effective, are beset with limitations, including high costs, time-intensiveness, and lack of real-time data. Emerging intelligent approaches address these challenges by providing real-time, accurate data on soil nutrient levels, thereby enabling timely and precise fertilization. Several case studies, including the Indian startups CropIn and Fasal, demonstrate the successful application of these technologies in agriculture, leading to improved crop yields, reduced fertilizer costs, and enhanced sustainability. The article also discusses ongoing research and prospects, highlighting the potential of AI not only in detection but also in predictive analysis. Finally, the piece provides a roadmap for farmers and stakeholders interested in adopting these intelligent approaches, emphasizing the importance of understanding the technology, choosing suitable tools, and fostering a mindset of change and continuous learning. Overall, intelligent approaches to soil nutrient detection promise a more productive, sustainable, and economically viable future in farming.
{"title":"Efficient Detection of Soil Nutrient Deficiencies through Intelligent Approaches","authors":"P. Ashoka, G. J. Avinash, M. T. Apoorva, Pranav Raj, M. Sekhar, Sanjay Singh, R. Vijay Kumar, Bal veer Singh","doi":"10.56557/bn/2023/v43i21877","DOIUrl":"https://doi.org/10.56557/bn/2023/v43i21877","url":null,"abstract":"Exploring the use of intelligent approaches, particularly artificial intelligence (AI) and machine learning (ML), in detecting soil nutrient deficiencies, is a crucial aspect of agriculture. Traditional methods of soil nutrient analysis, although effective, are beset with limitations, including high costs, time-intensiveness, and lack of real-time data. Emerging intelligent approaches address these challenges by providing real-time, accurate data on soil nutrient levels, thereby enabling timely and precise fertilization. Several case studies, including the Indian startups CropIn and Fasal, demonstrate the successful application of these technologies in agriculture, leading to improved crop yields, reduced fertilizer costs, and enhanced sustainability. The article also discusses ongoing research and prospects, highlighting the potential of AI not only in detection but also in predictive analysis. Finally, the piece provides a roadmap for farmers and stakeholders interested in adopting these intelligent approaches, emphasizing the importance of understanding the technology, choosing suitable tools, and fostering a mindset of change and continuous learning. Overall, intelligent approaches to soil nutrient detection promise a more productive, sustainable, and economically viable future in farming.","PeriodicalId":490896,"journal":{"name":"BIONATURE","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135146489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-18DOI: 10.56557/bn/2023/v43i21861
Jin-Won Park
The effect of cerivastatin (CER) on the permeability of lipid-raft-mimetic membrane was investigated. CER is a drug candidate to treat dyslipidemia and cardiovascular diseases. Sphingomyelin (SM) was used to form the outer layer of liposomes of which inner layer was prepared with dioleoylphosphatidic-acid. The permeability of the SM layer was estimated by measuring the release of the pyranine encapsulated in the liposome. The change of the permeability was analyzed with the presence of CER dispersion in PBS buffer, especially its hydrophobic group. The results of this study seem to be useful in deriving the drug candidate for cardiovascular disease.
{"title":"Effect of Cerivastatin on Permeability of Lipid-raft-mimetic Membranes","authors":"Jin-Won Park","doi":"10.56557/bn/2023/v43i21861","DOIUrl":"https://doi.org/10.56557/bn/2023/v43i21861","url":null,"abstract":"The effect of cerivastatin (CER) on the permeability of lipid-raft-mimetic membrane was investigated. CER is a drug candidate to treat dyslipidemia and cardiovascular diseases. Sphingomyelin (SM) was used to form the outer layer of liposomes of which inner layer was prepared with dioleoylphosphatidic-acid. The permeability of the SM layer was estimated by measuring the release of the pyranine encapsulated in the liposome. The change of the permeability was analyzed with the presence of CER dispersion in PBS buffer, especially its hydrophobic group. The results of this study seem to be useful in deriving the drug candidate for cardiovascular disease.","PeriodicalId":490896,"journal":{"name":"BIONATURE","volume":"124 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135207355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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