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Indications, modalities, and outcomes of surgery for ulcerative colitis in 2024 2024 年溃疡性结肠炎手术的适应症、方式和结果
IF 2.1 4区 医学 Q2 SURGERY Pub Date : 2024-06-01 DOI: 10.1016/j.jviscsurg.2024.05.004
Océane Lelièvre , Stéphane Benoist , Antoine Brouquet

Treatment of ulcerative colitis (UC) has been revolutionized by the arrival of biotherapies and technical progress in interventional endoscopy and surgery. (Sub)total emergency colectomy is required in the event of complicated severe acute colitis: colectasis, perforation, hemorrhage, organ failure. Corticosteroid therapy is the reference treatment for uncomplicated severe acute colitis, while infliximab and ciclosporin are 2nd-line treatments. At each step, before and after each line of treatment failure, surgery should be considered as an option. In cases refractory to medical treatment, the choice between surgery and change in medication must weigh the chronic symptoms associated with the disease against the risks of postoperative complications and functional sequelae inherent to surgery. Detection of dysplastic lesions necessitates chromoendoscopic imaging with multiple biopsies and anatomopathological verification. Endoscopic treatment of these lesions remains reserved for selected patients. These different indications call for multidisciplinary medical-surgical discussion. Total coloproctectomy with ileo-anal anastomosis (TCP-IAA) is the standard surgery, and it holds out hope for healing. Modalities depend on patient characteristics, previous emergency colectomy, and presence of dysplasia. It may be carried out in one, in two modified, or in three phases. The main complications are anastomotic fistula, short-term pouch-related fistula, ileo-anal pouch syndrome, pouchitis and long-term digestive and sexual disorders. For selected cases, an alternative can consist in total colectomy with ileo-rectal anastomosis or permanent terminal ileostomy. The objective of this update is to clarify the indications, modalities, and results of surgical treatment of ulcerative colitis in accordance with the most recent data in the literature.

生物疗法的出现以及介入性内窥镜和外科手术技术的进步为溃疡性结肠炎(UC)的治疗带来了革命性的变化。(如果出现复杂的严重急性结肠炎:结肠脓肿、穿孔、出血、器官衰竭,则需要进行(次)急诊全结肠切除术。皮质类固醇疗法是治疗无并发症重症急性结肠炎的参考疗法,而英夫利昔单抗和环孢素则是二线疗法。在每一步治疗失败前后,都应考虑选择手术治疗。对于药物治疗无效的病例,在选择手术还是换药时,必须权衡与疾病相关的慢性症状与手术后并发症和功能性后遗症的风险。要发现发育不良的病变,必须进行色内镜成像,并进行多次活检和解剖病理学验证。对这些病变的内窥镜治疗仍仅限于特定患者。这些不同的适应症需要多学科的内外科讨论。带回肠肛门吻合术的全结肠切除术(TCP-IAA)是标准手术,为治愈带来了希望。手术方式取决于患者的特征、之前的急诊结肠切除术以及是否存在发育不良。手术可分一次、两次或三次进行。主要并发症有吻合口瘘、短期内与肠袋有关的瘘管、回肠肛门肠袋综合征、肠袋炎以及长期的消化和性功能障碍。对于某些病例,可以选择全结肠切除术,同时进行回肠直肠吻合术或永久性末端回肠造口术。本次更新的目的是根据最新的文献数据,阐明溃疡性结肠炎手术治疗的适应症、方式和结果。
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引用次数: 0
Extended hepatectomy with biliary reconstruction over two separate segmental bile ducts for a Bismuth type IV or Rennes type X hilar cholangiocarcinoma (with video) 针对 Bismuth IV 型或 Rennes X 型肝门部胆管癌的扩大肝切除术,并在两个独立的胆管节段上进行胆道重建(附视频)。
IF 2.1 4区 医学 Q2 SURGERY Pub Date : 2024-06-01 DOI: 10.1016/j.jviscsurg.2024.03.001
Marie Livin , Stylianos Tzedakis , Heithem Jeddou
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引用次数: 0
SiLaT: A paradigm shift in the treatment of pilonidal disease? SiLaT:朝天鼻病治疗模式的转变?
IF 2.1 4区 医学 Q2 SURGERY Pub Date : 2024-06-01 DOI: 10.1016/j.jviscsurg.2024.03.007
Mélanie Draullette , Vincent de Parades , Amine Antonin Alam , Nadia Fathallah , Anne-Laure Rentien , Paul Benfredj , Manuel Aubert , Élise Pommaret , Hélène Beaussier , Audrey Fels , Lucas Spindler

Background

Pilonidal disease (PD) is a common condition for which the global incidence is increasing. Surgery is the currently preferred approach to treatment but there is a growing interest in new minimally invasive techniques, such as sinus laser therapy (SiLaT).

Aim

Our primary objective was to assess the efficacy of SiLaT for the treatment of pilonidal disease. The secondary objectives were to evaluate morbidity and patient satisfaction and identify predictive factors of success.

Methods

All adult patients, who underwent SiLaT in our department for a primary or recurrent pilonidal sinus from June 1, 2018, to December 31, 2020, were included in the study. Healing was defined as the closure of cutaneous orifices and the absence of seepage or abscesses.

Results

In total, 111 consecutive patients, for whom the male/female sex ratio was 2.1 and the mean age 28.8 (± 9.4) years, were included in this study. Eighteen (16.2%) patients had already undergone prior surgery for PD. The mean follow-up was 339.2 (± 221.4) days. A healing rate of 78.4% was observed, with a median time to healing of 20.0 days (15.0–30.0). The median time to return to usual activities was three days (1–7). The only postoperative complication was bleeding, which occurred for two patients (1.8%). Eighty-two patients (88.2%) reported being “very satisfied” with the treatment. Multivariate analysis showed no predictive factors for healing among the studied variables.

Conclusion

SiLaT is an efficient and safe procedure for the treatment of PD, with a high level of patient satisfaction. It will now be necessary to position it within the therapeutic algorithm.

背景:蝶窦疾病(PD)是一种常见疾病,全球发病率正在上升。手术是目前首选的治疗方法,但人们对鼻窦激光疗法(SiLaT)等新型微创技术的兴趣与日俱增。次要目标是评估发病率和患者满意度,并确定成功的预测因素:研究纳入了2018年6月1日至2020年12月31日期间在我科接受SiLaT治疗原发性或复发性朝天鼻窦的所有成年患者。痊愈的定义是皮肤孔口闭合,无渗液或脓肿:本研究共纳入 111 名连续患者,男女性别比为 2.1,平均年龄为 28.8(± 9.4)岁。其中有 18 名患者(16.2%)曾接受过腰椎间盘突出症手术。平均随访时间为 339.2 (± 221.4) 天。痊愈率为78.4%,中位痊愈时间为20.0天(15.0-30.0)。恢复正常活动的中位时间为三天(1-7 天)。术后唯一的并发症是出血,有两名患者(1.8%)发生了这种情况。82名患者(88.2%)表示对治疗 "非常满意"。多变量分析表明,所研究的变量中没有预测痊愈的因素:SiLaT是一种高效、安全的PD治疗方法,患者满意度很高。现在有必要将其纳入治疗方案。
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引用次数: 0
Press review 新闻评论
IF 2.1 4区 医学 Q2 SURGERY Pub Date : 2024-06-01 DOI: 10.1016/j.jviscsurg.2024.05.001
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引用次数: 0
Management after local excision of small rectal cancers. Indications for completion total mesorectal excision and possible alternatives 小直肠癌局部切除术后的处理。全直肠系膜切除术的适应症和可能的替代方案。
IF 2.1 4区 医学 Q2 SURGERY Pub Date : 2024-06-01 DOI: 10.1016/j.jviscsurg.2024.02.003
Camélia Labiad , Hadrien Alric , Maximilien Barret , Antoine Cazelles , Gabriel Rahmi , Mehdi Karoui , Gilles Manceau

The treatment of superficial rectal cancers (local excision, or proctectomy with total mesorectal excision (TME) remains controversial. Endoscopy and endorectal ultrasonography are essential for the precise initial definition of these small cancers. During endoscopy, the depth of the lesion can be estimated using virtual chromoendoscopy with magnification, thereby aiding the assessment of the possibilities of local excision. Current international recommendations indicate completion proctectomy after wide local excision for cases where the pathologic examination reveals poorly-differentiated lesions, lymphovascular invasion, grade 2 or 3 tumor budding, and incomplete resection. But debate persists regarding whether the depth of submucosal invasion can accurately predict the risk of lymph node spread. Recent data from the literature suggest that the depth of submucosal invasion should no longer, by itself, be an indication for additional oncological surgery. Adjuvant radio-chemotherapy could be an alternative to completion proctectomy in patients with pT1 rectal cancer and unfavorable histopathological criteria. A Dutch randomized controlled trial is underway to validate this strategy.

浅表直肠癌的治疗方法(局部切除或直肠切除加直肠系膜全切术(TME))仍存在争议。内窥镜检查和肛门直肠内超声波检查对初步精确界定这些小癌至关重要。在内窥镜检查过程中,可以使用放大的虚拟色内窥镜估计病变的深度,从而帮助评估局部切除的可能性。目前国际上的建议是,如果病理检查发现病灶分化不佳、淋巴管受侵、2 级或 3 级肿瘤出芽以及切除不彻底,则应在局部广泛切除后进行完整的直肠切除术。但关于粘膜下浸润深度能否准确预测淋巴结扩散风险的争论一直存在。最近的文献数据表明,粘膜下侵犯的深度本身不应再作为额外肿瘤手术的指征。对于 pT1 直肠癌且组织病理学标准不佳的患者,辅助放射化疗可作为完整直肠切除术的替代方案。荷兰正在进行一项随机对照试验,以验证这一策略。
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引用次数: 0
Treatment of low colorectal anastomotic leaks with transanal negative pressure 经肛负压治疗低位结直肠吻合口瘘。
IF 2.1 4区 医学 Q2 SURGERY Pub Date : 2024-06-01 DOI: 10.1016/j.jviscsurg.2019.09.002
P.-A. Tokoto, N.C. Buchs, D. Massalou
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引用次数: 0
Hemorrhoidal disease: Epidemiological study and analysis of predictive factors for surgical management 痔疮疾病:流行病学研究和手术治疗预测因素分析
IF 2.1 4区 医学 Q2 SURGERY Pub Date : 2024-06-01 DOI: 10.1016/j.jviscsurg.2024.03.005
Nadia Fathallah, Amine Alam, Anne L. Rentien, Giorgio La Greca, Joshua Co, Elise Pommaret, Amélie Barré, Stéphane Kegne, Hélène Beaussier, Lucas Spindler, Vincent de Parades

Introduction

There are very few French studies on hemorrhoidal disease and its management.

Patients and methods

Prospective single-center study from July to December 2021 including 472 patients.

Results

Bleeding, prolapse and pain were the main reasons for consultation. Treatment modalities were medical (44%), ± instrumental (72%), and surgical (17%). After treatment, the bleeding score and prolapse score decreased significantly (P = 0.002 and P  0.0001, respectively), but improvement was more marked in the surgery group with a better rate of “very good satisfaction” (73% vs. 54%, P = 0.003). Factors associated with likelihood of surgical treatment were: age > 44 years, hypertrophic perianal skin tags, high scores (Bristol > 5, bleeding > 5, prolapse > 2), severe impact on quality of life, smoking and reading during bowel movements. We have developed an online application, which aims to assess the risk of requiring hemorrhoidal surgery.

Conclusion

Less than 20% of patients who present with hemorrhoidal disease require surgical treatment, but it is associated with better effectiveness despite more complex postoperative consequences that sometimes motivate patient refusal. We have highlighted factors associated with surgical management, which can guide the practitioner in their therapeutic choices.

法国关于痔疮及其治疗的研究很少。这项前瞻性单中心研究于 2021 年 7 月至 12 月进行,包括 472 名患者。出血、脱垂和疼痛是就诊的主要原因。治疗方式为药物治疗(44%)、器械治疗(72%)和手术治疗(17%)。治疗后,出血评分和脱垂评分明显下降(分别=0.002和≤0.0001),但手术组的改善更明显,"非常满意 "率更高(73%对54%,=0.003)。与手术治疗可能性相关的因素有:年龄大于 44 岁、肛周皮肤标签肥厚、评分较高(布里斯托尔>5、出血>5、脱垂>2)、严重影响生活质量、吸烟和排便时阅读。我们开发了一款在线应用程序,旨在评估需要进行痔疮手术的风险。只有不到 20% 的痔疮患者需要接受手术治疗,但手术治疗效果更好,尽管术后后果更复杂,有时会促使患者拒绝手术治疗。我们强调了与手术治疗相关的因素,这些因素可以为医生的治疗选择提供指导。
{"title":"Hemorrhoidal disease: Epidemiological study and analysis of predictive factors for surgical management","authors":"Nadia Fathallah,&nbsp;Amine Alam,&nbsp;Anne L. Rentien,&nbsp;Giorgio La Greca,&nbsp;Joshua Co,&nbsp;Elise Pommaret,&nbsp;Amélie Barré,&nbsp;Stéphane Kegne,&nbsp;Hélène Beaussier,&nbsp;Lucas Spindler,&nbsp;Vincent de Parades","doi":"10.1016/j.jviscsurg.2024.03.005","DOIUrl":"10.1016/j.jviscsurg.2024.03.005","url":null,"abstract":"<div><h3>Introduction</h3><p>There are very few French studies on hemorrhoidal disease and its management.</p></div><div><h3>Patients and methods</h3><p>Prospective single-center study from July to December 2021 including 472 patients.</p></div><div><h3>Results</h3><p>Bleeding, prolapse and pain were the main reasons for consultation. Treatment modalities were medical (44%),<!--> <!-->±<!--> <!-->instrumental (72%), and surgical (17%). After treatment, the bleeding score and prolapse score decreased significantly (<em>P</em> <!-->=<!--> <!-->0.002 and <em>P</em> <!-->≤<!--> <!-->0.0001, respectively), but improvement was more marked in the surgery group with a better rate of “very good satisfaction” (73% vs. 54%, <em>P</em> <!-->=<!--> <!-->0.003). Factors associated with likelihood of surgical treatment were: age<!--> <!-->&gt;<!--> <!-->44<!--> <!-->years, hypertrophic perianal skin tags, high scores (Bristol<!--> <!-->&gt;<!--> <!-->5, bleeding<!--> <!-->&gt;<!--> <!-->5, prolapse<!--> <!-->&gt;<!--> <!-->2), severe impact on quality of life, smoking and reading during bowel movements. We have developed an online application, which aims to assess the risk of requiring hemorrhoidal surgery.</p></div><div><h3>Conclusion</h3><p>Less than 20% of patients who present with hemorrhoidal disease require surgical treatment, but it is associated with better effectiveness despite more complex postoperative consequences that sometimes motivate patient refusal. We have highlighted factors associated with surgical management, which can guide the practitioner in their therapeutic choices.</p></div>","PeriodicalId":49271,"journal":{"name":"Journal of Visceral Surgery","volume":"161 3","pages":"Pages 161-166"},"PeriodicalIF":2.1,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1878788624000304/pdfft?md5=cf214765814f96ac41f8e80435239c54&pid=1-s2.0-S1878788624000304-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140579907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The challenge of sodium-glucose cotransporter type 2 (SGLT2) inhibitors in the treatment of type 2 diabetes: Does their efficacy outweigh infectious risks? 钠-葡萄糖共转运体 2 型 (SGLT2) 抑制剂在治疗 2 型糖尿病方面面临的挑战:其疗效是否大于感染风险?
IF 2.1 4区 医学 Q2 SURGERY Pub Date : 2024-06-01 DOI: 10.1016/j.jviscsurg.2024.01.001
Anne-Cécile Ezanno , Pierre-Louis Conan , Cyril Garcia
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引用次数: 0
Cecal volvulus in complete common mesentery 完全性总肠系膜盲肠卷曲。
IF 2.1 4区 医学 Q2 SURGERY Pub Date : 2024-06-01 DOI: 10.1016/j.jviscsurg.2024.02.006
Ghita Taki , Victoire Roblot , Karine Pautrat

Common mesentery is an abnormal rotation of the primary umbilical loop characterized by inverted positioning of the mesenteric vessels; the mesenteric vein is displaced to the left of the artery. The inversion can be complete or incomplete. If it is incomplete, the mesenteric root is very short, with an empty right iliac fossa and the caecum in high median or subhepatic position. If it is complete, the entire small intestine is on the right, the entire large intestine is on the left; there is no third duodenum, and the second duodenum is anastomosed in the jejunum to the right of the superior mesenteric vessels. Cecal volvulus is a rarely encountered cause of acute intestinal occlusion and should be considered as a surgical emergency. There exist two main types of volvulus: by twisting of the large intestine around its axis, which remains in place; or by tilt and to rotation of the colon, which changes position.

共肠系膜是原脐环的异常旋转,其特点是肠系膜血管位置倒置;肠系膜静脉移位到动脉左侧。倒置可以是完全的,也可以是不完全的。如果是不完全内翻,肠系膜根部非常短,右侧髂窝空虚,盲肠处于高位正中或肝下位置。如果是完全性的,整个小肠在右侧,整个大肠在左侧;没有第三十二指肠,第二十二指肠吻合在肠系膜上血管右侧的空肠中。盲肠旋涡是急性肠梗阻的一种罕见病因,应视为外科急症。有两种主要的肠旋转类型:一种是大肠绕其轴线扭转,保持原位;另一种是结肠倾斜和旋转,改变位置。
{"title":"Cecal volvulus in complete common mesentery","authors":"Ghita Taki ,&nbsp;Victoire Roblot ,&nbsp;Karine Pautrat","doi":"10.1016/j.jviscsurg.2024.02.006","DOIUrl":"10.1016/j.jviscsurg.2024.02.006","url":null,"abstract":"<div><p>Common mesentery is an abnormal rotation of the primary umbilical loop characterized by inverted positioning of the mesenteric vessels; the mesenteric vein is displaced to the left of the artery. The inversion can be complete or incomplete. If it is incomplete, the mesenteric root is very short, with an empty right iliac fossa and the caecum in high median or subhepatic position. If it is complete, the entire small intestine is on the right, the entire large intestine is on the left; there is no third duodenum, and the second duodenum is anastomosed in the jejunum to the right of the superior mesenteric vessels. Cecal volvulus is a rarely encountered cause of acute intestinal occlusion and should be considered as a surgical emergency. There exist two main types of volvulus: by twisting of the large intestine around its axis, which remains in place; or by tilt and to rotation of the colon, which changes position.</p></div>","PeriodicalId":49271,"journal":{"name":"Journal of Visceral Surgery","volume":"161 3","pages":"Pages 226-227"},"PeriodicalIF":2.1,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140060894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mesenteric and portal venous resections during pancreatoduodenectomy 胰十二指肠切除术中的肠系膜和门静脉切除术。
IF 2.1 4区 医学 Q2 SURGERY Pub Date : 2024-06-01 DOI: 10.1016/j.jviscsurg.2024.04.003
Doris Da Silva , Jean-Christophe Vaillant , Sebastien Gaujoux
{"title":"Mesenteric and portal venous resections during pancreatoduodenectomy","authors":"Doris Da Silva ,&nbsp;Jean-Christophe Vaillant ,&nbsp;Sebastien Gaujoux","doi":"10.1016/j.jviscsurg.2024.04.003","DOIUrl":"10.1016/j.jviscsurg.2024.04.003","url":null,"abstract":"","PeriodicalId":49271,"journal":{"name":"Journal of Visceral Surgery","volume":"161 3","pages":"Pages 200-205"},"PeriodicalIF":2.1,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1878788624000547/pdfft?md5=4a1c3366b283a38f54403718d9eb944b&pid=1-s2.0-S1878788624000547-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140759007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Visceral Surgery
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