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Incidental presentation of appendix neuroendocrine tumor: Long-term results from a single institution. 阑尾神经内分泌肿瘤的附带表现:来自单一机构的长期结果。
IF 1.1 4区 医学 Q4 EMERGENCY MEDICINE Pub Date : 2023-09-01 DOI: 10.14744/tjtes.2023.78038
Marlen Süleyman, Abdullah Senlikci, Abdullah Durhan, Koray Kosmaz

Background: Appendix neuroendocrine tumors (NETs) are the most common tumors of the appendix and are most often diagnosed incidentally. The aim of this study was to retrospectively evaluate appendix NETs diagnosed incidentally in our clinic.

Methods: Of 8304 patients who underwent appendectomy with the diagnosis of acute appendicitis in Ankara Training and Re-search Hospital, General Surgery Clinic between January 2009 and January 2022, 33 had histopathology results evaluated as appendix NET, and a retrospective analysis was made of these cases. The patients were evaluated in terms of age, gender, tumor infiltration, tumor location, tumor size, surgical margin, tumor World Health Organization grade, surgery performed, lymph node metastasis, Ki67 index, number of mitosis, follow-up time, and survival.

Results: The rate of appendix NET was found to be 0.4%. The 33 cases comprised 15 (45.5%) males and 18 (54.5%) females with a mean age of 35.48 years (range: 16-84 years). Positive surgical margin was determined in 1 (3.03%) case, in which right hemicolectomy was performed. All other cases were followed up after appendectomy. The median follow-up was 89 (7-145) months. No recurrence was observed in any case. Mortality developed during follow-up in one case due to non-tumoral causes.

Conclusion: Appendix NETs are generally asymptomatic and appear incidentally after appendectomy due to acute appendicitis. Appendix NETs diagnosed incidentally are generally below 2 cm and have a good prognosis.

背景:阑尾神经内分泌肿瘤(NETs)是阑尾中最常见的肿瘤,通常是偶然诊断出来的。本研究的目的是回顾性评估在我们诊所偶然诊断的阑尾NETs。方法:在2009年1月至2022年1月期间,在安卡拉普通外科诊所培训和重新搜索医院接受阑尾切除术并诊断为急性阑尾炎的8304名患者中,33名患者的组织病理学结果被评估为阑尾NET,并对这些病例进行回顾性分析。根据年龄、性别、肿瘤浸润、肿瘤位置、肿瘤大小、手术切缘、世界卫生组织肿瘤分级、手术方式、淋巴结转移、Ki67指数、有丝分裂次数、随访时间和生存率对患者进行评估。结果:阑尾NET发生率为0.4%,33例中男性15例(45.5%),女性18例(54.5%),平均年龄35.48岁(16-84岁)。1例(3.03%)手术切缘阳性,其中右半结肠切除术。所有其他病例均在阑尾切除术后随访。中位随访时间为89(7-145)个月。在任何情况下均未观察到复发。一例患者在随访期间因非肿瘤原因死亡。结论:阑尾NETs通常无症状,在急性阑尾炎阑尾切除术后偶然出现。偶然诊断的阑尾NETs通常在2厘米以下,预后良好。
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引用次数: 0
Comparison of sinus tarsi approach versus extensile lateral approach in the management of displaced intra-articular calcaneal fractures: A single-center study. 跗骨窦入路与可伸展外侧入路治疗移位跟骨关节内骨折的比较:一项单中心研究。
IF 1.1 4区 医学 Q4 EMERGENCY MEDICINE Pub Date : 2023-09-01 DOI: 10.14744/tjtes.2023.13642
Mehmet Ersin, Mehmet Demirel, Mehmet Ekinci, İbrahim Sungur, Murat Yilmaz

Background: Controversy still exists for optimal treatment for displaced intra-articular calcaneal fractures (DIACFs). Conven-tionally, the extensile lateral approach (ELA) has been the most preferred approach. Although ELA provides excellent fracture access and direct evaluation of the depressed posterior facet, this approach has a high rate of serious complications, such as hematoma, superficial/deep infection, and wound healing issues. To overcome such complications, more minimally invasive techniques including external fixation, percutaneous fixation, arthroscopic assisted fixation, and sinus tarsi approach (STA) have been recently described. The primary aim of this study was to compare STA and LEA in the treatment of DIACFs.

Methods: Patients who were operated for DIACFs in our clinic were included in the study. Patients with closed DIACFs of Sanders Type II, III, IV, and over 18 years of age were identified. Physical examinations and radiological evaluations of the patients were per-formed, and clinical scores were filled. Patients were divided into subgroups according to the Sander's classification and comparisons were made again according to these subgroups.

Results: There were 37 patients (four female and 33 male) in STA group and 44 patients in LEA group (six female and 38 male). The mean age was 44.42±13.57 years (range, 18-61) for STA group and 37.32±11.09 years (range, 18-56) for the LEA group. In clinical outcomes, except for short-form survey (SF-12)/MCS-12 (Mental Score) and visual analog scale score, all the parameters were signifi-cantly better in STA group compared to LEA group. No significant difference was observed between the two groups in radiographic results, except for the Böhler angle. Significantly less infection occurred in the STA group compared to LEA group (P=0.021). According to Sander's classification, American Orthopedic Foot and Ankle Society, foot and ankle disability index, and SF-12/PCS-12 and foot function index scores, no significant differences were determined between STA and LEA groups for Sanders Type 2, whereas the values were considerably higher in STA group than in LEA group for Sanders Type 3 and 4.

Conclusion: In DIACFs, STA is considered a safe and effective method for restoring the width, height, and length of the calca-neus and reconstruction of joint alignment and has now become our standard technique for all calcaneal fractures requiring operative treatment.

背景:移位跟骨关节内骨折(DIACF)的最佳治疗方法仍存在争议。传统上,伸展侧入路(ELA)是最受欢迎的入路。尽管ELA提供了极好的骨折途径和对凹陷的后小关节的直接评估,但这种方法有很高的严重并发症发生率,如血肿、浅表/深部感染和伤口愈合问题。为了克服这些并发症,最近描述了更多的微创技术,包括外固定、经皮固定、关节镜辅助固定和睑板窦入路(STA)。本研究的主要目的是比较STA和LEA在治疗DIACF中的作用。方法:将在我们诊所接受DIACF手术的患者纳入研究。确定了Sanders II型、III型、IV型和18岁以上的闭合性DIACF患者。对患者进行体检和放射学评估,并填写临床评分。根据Sander分类法将患者分为亚组,并根据这些亚组再次进行比较。结果:STA组37例(4女33男),LEA组44例(6女38男)。STA组的平均年龄为44.42±13.57岁(范围18-61),LEA组为37.32±11.09岁(范围18-26)。在临床结果方面,除了简短问卷(SF-12)/MCS-12(心理评分)和视觉模拟量表评分外,STA组的所有参数都明显优于LEA组。除了Böhler角外,两组的放射学结果没有显著差异。与LEA组相比,STA组的感染发生率显著降低(P=0.021)。根据Sander分类、美国足踝矫形学会、足部和踝关节残疾指数、SF-12/PCS-12和足部功能指数评分,在Sanders 2型方面,STA和LEA组之间没有显着差异,而Sanders 3型和4型的STA组的值明显高于LEA组。结论:在DIACF中,STA被认为是恢复跟骨宽度、高度和长度以及重建关节排列的一种安全有效的方法,现在已成为我们治疗所有需要手术治疗的跟骨骨折的标准技术。
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引用次数: 0
Research of Importance of Thiol, CRP and Lactate in Diagnosing Mesenteric Ischemia At An Early Stage: Animal Model. 硫醇、CRP和乳酸在早期诊断肠系膜缺血中的重要性研究:动物模型。
IF 1.1 4区 医学 Q4 EMERGENCY MEDICINE Pub Date : 2023-09-01 DOI: 10.14744/tjtes.2023.45234
Fırat Canlıkarakaya, Bülent Cavit Yüksel, Sadettin Er, Yasir Keçelioğlu, Salim Neselioglu

Introduction and purpose: Acute mesenteric ischemia is especially seen in the elderly population. It has an increasing incidence in today's world where the average life expectancy is increasing. Early diagnosis is the most important factor reducing morbidity and mortality, and there is still no marker with high sensitivity and specificity for early diagnosis.In this study, we aimed to find a more sensitive and specific serum marker in the early diagnosis of mesenteric ischemia by comparing thiol with the currently used markers C-reactive protein and lactate.

Materials and methods: In our study, 32 Wistar Albino male rats, 10-12 weeks old, weighing 250-300 g, were used. 32 rats were divided into 4 groups, one of which was the control group. The superior mesenteric artery of the other 3 groups was ligated. Blood samples were taken after 2 hours from the first group, 4 hours from the second group, and 6 hours from the third group. Then the rats were sacrificed. Mesenteric ischemia and its level were observed in sacrificed subjects. The samples were separated under appropriate conditions and analyzed biochemically.

Results: As the ischemia time increased, CRP increased and this increase was found to be statistically insignificant (p>0.05). The changes in lactate were found to be statistically significant (p<0.05). The difference between the changes of total and native thiol values was found to be statistically significant (p<0.05).

Conclusion: Although CRP is a non-specific parameter in the early diagnosis of acute mesenteric ischemia, lactate maintains its importance as seen in our study. Differences in total thiol and native thiol changes were statistically significant. The fact that this significant difference is observed at the 4th hour values, reveals the importance of these parameters in early diagnosis. Thanks to the economic and fast results of thiol parameters, it is thought that new studies to be added to the literature can lead to the diagnosis of mesenteric ischemia.

引言和目的:急性肠系膜缺血在老年人群中尤为常见。在当今世界平均预期寿命不断增加的情况下,这种疾病的发病率越来越高。早期诊断是降低发病率和死亡率的最重要因素,目前还没有对早期诊断具有高灵敏度和特异性的标志物。在这项研究中,我们旨在通过将硫醇与目前使用的标记物C反应蛋白和乳酸进行比较,找到一种更灵敏、更特异的血清标记物,用于肠系膜缺血的早期诊断。材料和方法:在我们的研究中,32只Wistar Albino雄性大鼠,10-12周龄,体重250-300g。将32只大鼠分为4组,其中1组为对照组。其余3组均结扎肠系膜上动脉。第一组在2小时后、第二组在4小时后和第三组在6小时后采集血样。然后处死大鼠。在处死的受试者中观察肠系膜缺血及其水平。在适当的条件下分离样品并进行生物化学分析。结果:随着缺血时间的增加,CRP升高,且这种升高在统计学上不显著(p>0.05)。乳酸盐的变化在统计学上显著(结论:尽管CRP在急性肠系膜缺血的早期诊断中是一个非特异性参数,但正如我们的研究所见,乳酸仍然具有其重要性。总硫醇和天然硫醇变化的差异具有统计学意义。在第4小时观察到这种显著差异,这一事实揭示了这些参数在早期诊断中的重要性硫醇参数的经济快速结果,认为新的研究可以增加到文献中,从而对肠系膜缺血进行诊断。
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引用次数: 0
Is diagnostic laparoscopy necessary in the management of left thoracoabdominal stab wounds? 诊断性腹腔镜检查在治疗左胸腹部刺伤中是否必要?
IF 1.1 4区 医学 Q4 EMERGENCY MEDICINE Pub Date : 2023-09-01 DOI: 10.14744/tjtes.2023.33423
Hasan Okmen, Kivilcim Ulusan, Acar Aren

Background: The diagnosis of a diaphragmatic rupture and the identification of patients for surgical repair is challenging despite current diagnostic algorithms and imaging technologies. Unless treated on time, acute traumatic diaphragmatic injury due to stab wounds has a high mortality and morbidity rate, with an increasing trend in the presence of organ herniation. In this study, we aimed to investigate the efficacy of diagnostic laparoscopy in patients with an anterior thoracoabdominal stab wound and to compare the follow-up outcomes of cases.

Methods: We retrospectively reviewed our institutional database of patients who were admitted with stab wounds between Oc-tober 2012 and 2022. Patients who underwent diagnostic laparoscopy were divided into two groups depending on the presence of a diaphragmatic injury. We analyzed demographics, the success of computed tomography (CT) imaging in the diagnosis, the presence of hemomediastinum, pneumomediastinum, tube thoracostomy application, associated organ injury, type of surgery, duration of surgery, complications, and the length of stay between the groups.

Results: Of the 39 patients with penetrating left thoracoabdominal injury underwent diagnostic laparoscopy, CT had a diagnostic sensitivity of 63.16% (95% Confidence interval [CI] 38.36-83.71%), and a specificity of 100% (95% CI 82.35-100.00%). We could not find a statistically significant difference between the groups in terms of studied variables, while operation time was significantly higher in the diaphragmatic injury group (P<0.01). Fourteen patients had accompanied visceral injuries.

Conclusion: Diagnostic laparoscopy is still the gold standard particularly in the ER setting, particularly in the absence of an experienced radiologist for 24 h and when the close monitoring of the patient by the same team cannot be provided.

背景:尽管目前有诊断算法和成像技术,但膈肌破裂的诊断和手术修复患者的识别仍然具有挑战性。除非及时治疗,否则由刺伤引起的急性创伤性膈肌损伤具有很高的死亡率和发病率,并且存在器官突出的增加趋势。在这项研究中,我们旨在研究诊断性腹腔镜在胸腹前刺伤患者中的疗效,并比较病例的随访结果。方法:我们回顾性回顾了2012年10月至2022年期间因刺伤入院的患者的机构数据库。根据膈肌损伤的存在,接受诊断性腹腔镜检查的患者被分为两组。我们分析了人口统计学、计算机断层扫描(CT)成像在诊断中的成功率、血纵隔的存在、纵隔气肿、导管胸腔造口术的应用、相关器官损伤、手术类型、手术持续时间、并发症以及两组之间的住院时间。结果:在39例左胸腹穿透性损伤患者中,CT的诊断敏感性为63.16%(95%可信区间[CI]38.36-83.71%),特异性为100%(95%可信置信区间82.35-100.00%),而膈肌损伤组的手术时间明显更长(P结论:诊断性腹腔镜检查仍然是金标准,特别是在急诊室环境中,尤其是在没有经验丰富的放射科医生24小时的情况下,以及在同一团队无法对患者进行密切监测的情况下。
{"title":"Is diagnostic laparoscopy necessary in the management of left thoracoabdominal stab wounds?","authors":"Hasan Okmen,&nbsp;Kivilcim Ulusan,&nbsp;Acar Aren","doi":"10.14744/tjtes.2023.33423","DOIUrl":"10.14744/tjtes.2023.33423","url":null,"abstract":"<p><strong>Background: </strong>The diagnosis of a diaphragmatic rupture and the identification of patients for surgical repair is challenging despite current diagnostic algorithms and imaging technologies. Unless treated on time, acute traumatic diaphragmatic injury due to stab wounds has a high mortality and morbidity rate, with an increasing trend in the presence of organ herniation. In this study, we aimed to investigate the efficacy of diagnostic laparoscopy in patients with an anterior thoracoabdominal stab wound and to compare the follow-up outcomes of cases.</p><p><strong>Methods: </strong>We retrospectively reviewed our institutional database of patients who were admitted with stab wounds between Oc-tober 2012 and 2022. Patients who underwent diagnostic laparoscopy were divided into two groups depending on the presence of a diaphragmatic injury. We analyzed demographics, the success of computed tomography (CT) imaging in the diagnosis, the presence of hemomediastinum, pneumomediastinum, tube thoracostomy application, associated organ injury, type of surgery, duration of surgery, complications, and the length of stay between the groups.</p><p><strong>Results: </strong>Of the 39 patients with penetrating left thoracoabdominal injury underwent diagnostic laparoscopy, CT had a diagnostic sensitivity of 63.16% (95% Confidence interval [CI] 38.36-83.71%), and a specificity of 100% (95% CI 82.35-100.00%). We could not find a statistically significant difference between the groups in terms of studied variables, while operation time was significantly higher in the diaphragmatic injury group (P<0.01). Fourteen patients had accompanied visceral injuries.</p><p><strong>Conclusion: </strong>Diagnostic laparoscopy is still the gold standard particularly in the ER setting, particularly in the absence of an experienced radiologist for 24 h and when the close monitoring of the patient by the same team cannot be provided.</p>","PeriodicalId":49398,"journal":{"name":"Ulusal Travma Ve Acil Cerrahi Dergisi-Turkish Journal of Trauma & Emergency Surgery","volume":"29 9","pages":"1026-1031"},"PeriodicalIF":1.1,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c6/81/TJTES-29-1026.PMC10560811.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10195562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Percutaneous cholecystostomy in the management of acute cholecystitis-comparative analysis of before and after the COVID 19 pandemic. 经皮胆囊造口术在治疗急性胆囊炎中的应用2019冠状病毒病大流行前后的比较分析。
IF 1.1 4区 医学 Q4 EMERGENCY MEDICINE Pub Date : 2023-09-01 DOI: 10.14744/tjtes.2023.22901
Fatih Kılınç, Çağlayan Çakır, Ömer Yıldız, Alpen Yahya Gümüşoğlu, Abdülcelil Gezmiş, Fidan Aygün

Background: Percutaneous cholecystostomy (PC) is a minimally invasive temporary treatment for patients with acute cholecys-titis (AC) who are at high risk for surgery. The aim of this study was to compare the characteristics of patients with AC treated with PC before and during the coronavirus disease 2019 (COVID 19) pandemic.

Methods: The data of patients who underwent PC with the diagnosis of AC between 2019 and 2021 were analyzed by scanning the hospital registry system. During the COVID 19 pandemic period of March 11, 2020, to March 11, 2021, 110 patients with AC were treated with PC. In the pre-pandemic period of March 2019 to March 2020, 99 patients who underwent PC were added to the study as a control group. The data of the 209 patients included in the study were recorded, and descriptive statistical analysis was performed. The patient characteristics of the two groups were compared.

Results: Evaluation was made of 209 patients who were diagnosed with AC between March 2019 and March 2021 and could not be operated on due to the high risk of surgery. The average age of the patients was 63.84 years (21-97) in the pandemic period and 68.43 years (31-100) in the pre-pandemic period. The rate of female patients was 45.5% in the pandemic group and 44.5% in the pre-pandemic group. The mean procedure-discharge time was 3.85 days in the pandemic period and 3.34 days pre-pandemic. The American Society of Anesthesiologists physical status classification (PS) was determined to be 1 or 2 in 56.4% of the pandemic group patients and 3 or 4 in 78.8% of the pre-pandemic group. There was no comorbidity accompanying AC in 45 (40.9%) patients in the pandemic period, and at least one comorbid condition accompanying AC was detected in 77 (77.8%) patients in the pre-pandemic period. The severity grading for AC was 2 (moderate) in 97.3% of the patients in the pandemic group and 3 (severe) in 26.3% of the patients in the pre-pandemic group. Of the 110 patients in the pandemic period, 14 were Covid 19 positive or suspected. PC-related mortality was not observed in either group.

Conclusion: PC is an effective and safe treatment method that reduced the operating room and intensive care burden during the exacerbation of the COVID 19 pandemic. Therefore, it seems like a logical option to expand the PC indications at times when the number of COVID 19 patients increases.

背景:经皮胆囊造口术(PC)是一种微创的临时治疗急性胆囊炎(AC)患者的方法,这些患者有很高的手术风险。本研究的目的是比较在2019冠状病毒病(COVID 19)大流行之前和期间接受PC治疗的AC患者的特征。方法:通过扫描医院登记系统,分析2019年至2021年间接受PC诊断为AC的患者的数据。在2020年3月11日至2021年3月1日的2019冠状病毒病大流行期间,110名AC患者接受了PC治疗。在2019年3月至2020年3月份的大流行前期间,99名接受PC治疗的患者被添加到研究中作为对照组。对纳入研究的209名患者的数据进行记录,并进行描述性统计分析。比较两组患者的特点。结果:对209名在2019年3月至2021年3月期间被诊断为AC的患者进行了评估,这些患者由于手术风险高而无法进行手术。患者的平均年龄在大流行期间为63.84岁(21-97岁),在大流行前为68.43岁(31-100岁)。女性患者的发病率在大流行组为45.5%,在大流行前组为44.5%。平均手术出院时间在大流行期间为3.85天,在大流行前为3.34天。美国麻醉师协会确定,56.4%的疫情组患者的身体状况分类(PS)为1或2,78.8%的疫情前患者的身体状态分类为3或4。在大流行期间,45名(40.9%)患者没有AC合并症,在大流行前期间,77名(77.8%)患者至少检测到一种AC合并症。疫情组97.3%的患者AC的严重程度分级为2级(中度),疫情前组26.3%的患者为3级(重度)。在大流行期间的110名患者中,有14名新冠肺炎19例呈阳性或疑似。两组均未观察到PC相关死亡率。结论:PC是一种有效、安全的治疗方法,在新冠肺炎疫情恶化期间减轻了手术室和重症监护负担。因此,在新冠肺炎患者人数增加的时候,扩大PC适应症似乎是一个合乎逻辑的选择。
{"title":"Percutaneous cholecystostomy in the management of acute cholecystitis-comparative analysis of before and after the COVID 19 pandemic.","authors":"Fatih Kılınç,&nbsp;Çağlayan Çakır,&nbsp;Ömer Yıldız,&nbsp;Alpen Yahya Gümüşoğlu,&nbsp;Abdülcelil Gezmiş,&nbsp;Fidan Aygün","doi":"10.14744/tjtes.2023.22901","DOIUrl":"10.14744/tjtes.2023.22901","url":null,"abstract":"<p><strong>Background: </strong>Percutaneous cholecystostomy (PC) is a minimally invasive temporary treatment for patients with acute cholecys-titis (AC) who are at high risk for surgery. The aim of this study was to compare the characteristics of patients with AC treated with PC before and during the coronavirus disease 2019 (COVID 19) pandemic.</p><p><strong>Methods: </strong>The data of patients who underwent PC with the diagnosis of AC between 2019 and 2021 were analyzed by scanning the hospital registry system. During the COVID 19 pandemic period of March 11, 2020, to March 11, 2021, 110 patients with AC were treated with PC. In the pre-pandemic period of March 2019 to March 2020, 99 patients who underwent PC were added to the study as a control group. The data of the 209 patients included in the study were recorded, and descriptive statistical analysis was performed. The patient characteristics of the two groups were compared.</p><p><strong>Results: </strong>Evaluation was made of 209 patients who were diagnosed with AC between March 2019 and March 2021 and could not be operated on due to the high risk of surgery. The average age of the patients was 63.84 years (21-97) in the pandemic period and 68.43 years (31-100) in the pre-pandemic period. The rate of female patients was 45.5% in the pandemic group and 44.5% in the pre-pandemic group. The mean procedure-discharge time was 3.85 days in the pandemic period and 3.34 days pre-pandemic. The American Society of Anesthesiologists physical status classification (PS) was determined to be 1 or 2 in 56.4% of the pandemic group patients and 3 or 4 in 78.8% of the pre-pandemic group. There was no comorbidity accompanying AC in 45 (40.9%) patients in the pandemic period, and at least one comorbid condition accompanying AC was detected in 77 (77.8%) patients in the pre-pandemic period. The severity grading for AC was 2 (moderate) in 97.3% of the patients in the pandemic group and 3 (severe) in 26.3% of the patients in the pre-pandemic group. Of the 110 patients in the pandemic period, 14 were Covid 19 positive or suspected. PC-related mortality was not observed in either group.</p><p><strong>Conclusion: </strong>PC is an effective and safe treatment method that reduced the operating room and intensive care burden during the exacerbation of the COVID 19 pandemic. Therefore, it seems like a logical option to expand the PC indications at times when the number of COVID 19 patients increases.</p>","PeriodicalId":49398,"journal":{"name":"Ulusal Travma Ve Acil Cerrahi Dergisi-Turkish Journal of Trauma & Emergency Surgery","volume":"29 9","pages":"978-986"},"PeriodicalIF":1.1,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ea/df/TJTES-29-978.PMC10560820.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10198778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prospective evolution of body compositions based on bioelectrical impedance analysis and water intake on patients with gallstone. 基于生物电阻抗分析和胆囊结石患者饮水的身体成分前瞻性演变。
IF 1.1 4区 医学 Q4 EMERGENCY MEDICINE Pub Date : 2023-08-01 DOI: 10.14744/tjtes.2023.94034
Mustafa Sami Bostan, Salih Yılmaz

Background: We aimed to compare bioelectrical impedance analysis (BIA) body composition and to reveal predictive factors that may help prevent gallstone formation.

Methods: Patients with gallstones by ultrasonography were selected as the case group, while participants without stones were selected as the control group. The body composition of the participants in both groups was measured by BIA. Demographic charac-teristics, mean water intake daily of the participants (MWID) and body mass index (BMI), total body fat mass (TBFM), total body fat percentage (BFP), total body water (TBW), body fat mass of trunk (BFM of trunk), and visceral fat level (VFL) measured by BIA were recorded. Predictive risk factors for gallstone formation were revealed by statistical analysis.

Results: The data of a total of 191 participants, including 83 participants in the group with gallstones and 108 participants in the group without gallstones, were analyzed. Both groups were statistically similar in terms of age and sex (P>0.05). In univariate analysis, BMI, TBFM, BFP, BFM of trunk, and VFL were statistically significantly higher (P = 0.007, P=0.004, P=0.003, P=0.003, and P=0.005, respectively) while MWID was lower (P<0.001) in the group with gallstone. In multivariate analysis, MWID (ref: ≥1.5 odds ratio [OR]: 7.786 95% confidence interval [CI]: 3.612-16.781) and BFP (ref: ≥0.24 OR: 3.102 95%CI: 1.207-7.972) were independent factors in gallstone formation.

Conclusion: The MWID and BFP level measured by the BIA technique, which is an easily applicable, noninvasive method, are independent risk factors for gallstone formation.

背景:我们旨在比较生物电阻抗分析(BIA)的身体成分,并揭示可能有助于预防胆结石形成的预测因素。方法:选择经超声检查有胆结石的患者作为病例组,选择无结石的参与者作为对照组。通过BIA测量两组参与者的身体成分。记录受试者的人口学特征、平均每日摄水量(MWID)和体重指数(BMI)、全身脂肪量(TBFM)、全身脂百分比(BFP)、全身水分(TBW)、躯干脂肪量(BFM)和BIA测量的内脏脂肪水平(VFL)。统计分析揭示了胆囊结石形成的预测危险因素。结果:对191名参与者的数据进行了分析,其中有胆结石组83名参与者和无胆结石组108名参与者。两组患者的年龄和性别差异无统计学意义(P>0.05),和VFL在统计学上显著较高(分别为P=0.007、P=0.004、P=0.003、P=0.003和P=0.005),而MWID较低(P结论:BIA技术测量的MWID和BFP水平是胆囊结石形成的独立危险因素,BIA技术是一种易于应用、无创的方法。
{"title":"Prospective evolution of body compositions based on bioelectrical impedance analysis and water intake on patients with gallstone.","authors":"Mustafa Sami Bostan,&nbsp;Salih Yılmaz","doi":"10.14744/tjtes.2023.94034","DOIUrl":"10.14744/tjtes.2023.94034","url":null,"abstract":"<p><strong>Background: </strong>We aimed to compare bioelectrical impedance analysis (BIA) body composition and to reveal predictive factors that may help prevent gallstone formation.</p><p><strong>Methods: </strong>Patients with gallstones by ultrasonography were selected as the case group, while participants without stones were selected as the control group. The body composition of the participants in both groups was measured by BIA. Demographic charac-teristics, mean water intake daily of the participants (MWID) and body mass index (BMI), total body fat mass (TBFM), total body fat percentage (BFP), total body water (TBW), body fat mass of trunk (BFM of trunk), and visceral fat level (VFL) measured by BIA were recorded. Predictive risk factors for gallstone formation were revealed by statistical analysis.</p><p><strong>Results: </strong>The data of a total of 191 participants, including 83 participants in the group with gallstones and 108 participants in the group without gallstones, were analyzed. Both groups were statistically similar in terms of age and sex (P>0.05). In univariate analysis, BMI, TBFM, BFP, BFM of trunk, and VFL were statistically significantly higher (P = 0.007, P=0.004, P=0.003, P=0.003, and P=0.005, respectively) while MWID was lower (P<0.001) in the group with gallstone. In multivariate analysis, MWID (ref: ≥1.5 odds ratio [OR]: 7.786 95% confidence interval [CI]: 3.612-16.781) and BFP (ref: ≥0.24 OR: 3.102 95%CI: 1.207-7.972) were independent factors in gallstone formation.</p><p><strong>Conclusion: </strong>The MWID and BFP level measured by the BIA technique, which is an easily applicable, noninvasive method, are independent risk factors for gallstone formation.</p>","PeriodicalId":49398,"journal":{"name":"Ulusal Travma Ve Acil Cerrahi Dergisi-Turkish Journal of Trauma & Emergency Surgery","volume":"29 8","pages":"850-857"},"PeriodicalIF":1.1,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0e/4f/TJTES-29-850.PMC10560795.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10346287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A new, simple marker for predicting complicated appendicitis in patients with normal white blood cell count indicator; LUC. 一种新的、简单的标记物,用于预测白细胞计数指标正常的患者并发阑尾炎;LUC。
IF 1.1 4区 医学 Q4 EMERGENCY MEDICINE Pub Date : 2023-08-01 DOI: 10.14744/tjtes.2023.60196
Erdinc Cetinkaya, Sukru Melih Bayazitli, Abidin Göktaş, Tezcan Akın, Ozgur Akgul, Sadettin Er, Enver Okan Hamamcı, Huseyin Berkem, Bülent Cavit Yüksel, Mesut Tez

Background: The aim of this study was to investigate the ability of a new marker that could be easily obtained to differentiate between complicated and uncomplicated appendicitis in a patients with a white blood cell (WBC) count within the normal range.

Methods: The patients who underwent surgery with histopathologically proven acute appendicitis (AA) between January 2021 and October 2022 were evaluated retrospectively. Patients were classified into two groups as uncomplicated and complicated appendicitis, based on the surgical and histopathological findings. Groups were compared in terms of laboratory parameters at the time of hospital admission.

Results: During the study period, 2589 patients underwent an appendectomy, among these 612 patients who had a WBC count within the normal range at the time of admission were analyzed. Uncomplicated appendicitis was detected in 79.6% of the patients and complicated appendicitis in 20.4%. Neutrophil%, neutrophil-to-lymphocyte ratio, C-reactive protein, and total bilirubin levels were significantly higher, whereas lymphocyte%, lymphocyte count, lymphocyte-to-monocyte ratio, sodium levels, and large unstained cells (LUC)% were significantly lower in patients with complicated appendicitis. Multiple logistic regression analysis revealed that lower LUC% (Odds Ratio [OR]: 0.45; 95% Confidence Intervals [CI]: 1.08-2.09; P=0.01) and higher total bilirubin levels (OR: 1.50; 95% CI: 1.08-2.09; P=0.01) were independent risk factors for complicated appendicitis.

Conclusion: In patients with a diagnosis of AA with a normal WBC value, LUC% obtained from the complete blood count can be used as a new parameter predicting the diagnosis of complicated appendicitis.

背景:本研究的目的是研究一种新的标记物的能力,该标记物可以很容易地在白细胞计数在正常范围内的患者中区分复杂和非复杂阑尾炎。方法:对2021年1月至2022年10月期间接受组织病理学证实的急性阑尾炎(AA)手术的患者进行回顾性评估。根据手术和组织病理学结果,将患者分为无并发症和复杂阑尾炎两组。根据入院时的实验室参数对各组进行比较。结果:在研究期间,2589名患者接受了阑尾切除术,对612名患者中入院时WBC计数在正常范围内的患者进行了分析。79.6%的患者检测到非复杂型阑尾炎,20.4%的患者检测出复杂型阑尾炎。中性粒细胞%、中性粒细胞与淋巴细胞比率、C反应蛋白和总胆红素水平显著升高,而淋巴细胞%、淋巴细胞计数、淋巴细胞与单核细胞比率、钠水平、,而大未染色细胞(LUC)%在复杂性阑尾炎患者中显著降低。多元逻辑回归分析显示,较低的LUC%(比值比[OR]:4.45;95%置信区间[CI]:1.08-2.09;P=0.01)和较高的总胆红素水平(OR:1.50;95%CI:1.08-2.09:P=0.01)是并发阑尾炎的独立危险因素。结论:在诊断为AA且WBC值正常的患者中,从全血细胞计数中获得的LUC%可作为预测复杂阑尾炎诊断的新参数。
{"title":"A new, simple marker for predicting complicated appendicitis in patients with normal white blood cell count indicator; LUC.","authors":"Erdinc Cetinkaya,&nbsp;Sukru Melih Bayazitli,&nbsp;Abidin Göktaş,&nbsp;Tezcan Akın,&nbsp;Ozgur Akgul,&nbsp;Sadettin Er,&nbsp;Enver Okan Hamamcı,&nbsp;Huseyin Berkem,&nbsp;Bülent Cavit Yüksel,&nbsp;Mesut Tez","doi":"10.14744/tjtes.2023.60196","DOIUrl":"10.14744/tjtes.2023.60196","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to investigate the ability of a new marker that could be easily obtained to differentiate between complicated and uncomplicated appendicitis in a patients with a white blood cell (WBC) count within the normal range.</p><p><strong>Methods: </strong>The patients who underwent surgery with histopathologically proven acute appendicitis (AA) between January 2021 and October 2022 were evaluated retrospectively. Patients were classified into two groups as uncomplicated and complicated appendicitis, based on the surgical and histopathological findings. Groups were compared in terms of laboratory parameters at the time of hospital admission.</p><p><strong>Results: </strong>During the study period, 2589 patients underwent an appendectomy, among these 612 patients who had a WBC count within the normal range at the time of admission were analyzed. Uncomplicated appendicitis was detected in 79.6% of the patients and complicated appendicitis in 20.4%. Neutrophil%, neutrophil-to-lymphocyte ratio, C-reactive protein, and total bilirubin levels were significantly higher, whereas lymphocyte%, lymphocyte count, lymphocyte-to-monocyte ratio, sodium levels, and large unstained cells (LUC)% were significantly lower in patients with complicated appendicitis. Multiple logistic regression analysis revealed that lower LUC% (Odds Ratio [OR]: 0.45; 95% Confidence Intervals [CI]: 1.08-2.09; P=0.01) and higher total bilirubin levels (OR: 1.50; 95% CI: 1.08-2.09; P=0.01) were independent risk factors for complicated appendicitis.</p><p><strong>Conclusion: </strong>In patients with a diagnosis of AA with a normal WBC value, LUC% obtained from the complete blood count can be used as a new parameter predicting the diagnosis of complicated appendicitis.</p>","PeriodicalId":49398,"journal":{"name":"Ulusal Travma Ve Acil Cerrahi Dergisi-Turkish Journal of Trauma & Emergency Surgery","volume":"29 8","pages":"872-876"},"PeriodicalIF":1.1,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/72/57/TJTES-29-872.PMC10560799.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10040619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A revolutionary acute subdural hematoma detection based on two-tiered artificial intelligence model. 基于两层人工智能模型的革命性急性硬膜下血肿检测。
IF 1.1 4区 医学 Q4 EMERGENCY MEDICINE Pub Date : 2023-08-01 DOI: 10.14744/tjtes.2023.76756
İsmail Kaya, Tuğrul Hakan Gençtürk, Fidan Kaya Gülağız

Background: The article was planned to make the first evaluation in terms of acute subdural hemorrhages, thinking that it can help in appropriate pathologies by tomography interpretation with the artificial intelligence (AI) method, at least in a way to quickly warn the responsible doctor.

Methods: A two-level AI-based hybrid method was developed. The proposed model uses the mask-region convolutional neural network (Mask R-CNN) technique, which is a deep learning model, in the hemorrhagic region's mask generation stage, and a problem-specific, optimized support vector machines (SVM) technique which is a machine learning model in the binary classification stage. Furthermore, the bee colony algorithm was used for the optimization of SVM algorithms' parameters.

Results: In the first stage, the mean average precision (mAP) value was obtained as 0.754 when the intercept over union (IOU) value was taken as 0.5 with the Mask R-CNN architecture used. At the same time, when a 5-fold cross-validation was applied, the mAP value was obtained 0.736. With the hyperparameter optimization for both Mask R-CNN and the SVM algorithm, the accuracy of the two-level classification process was obtained as 96.36%. Furthermore, final false-negative rate and false-positive rate values were obtained as 6.20%, and 2.57%, respectively.

Conclusion: With the proposed model, both the detection of hemorrhage and the presentation of the suspicious area to the physician were performed more successfully on two dimensional (2D) images with low cost and high accuracy compared to similar studies and today's interpretations with telemedicine techniques.

背景:这篇文章计划对急性硬膜下出血进行首次评估,认为它可以通过人工智能(AI)方法的断层扫描解释来帮助进行适当的病理检查,至少在某种程度上可以快速警告负责任的医生。方法:提出一种基于两级人工智能的混合方法。所提出的模型在出血区域的掩模生成阶段使用了掩模区域卷积神经网络(mask R-CNN)技术,这是一种深度学习模型,以及在二元分类阶段使用了针对特定问题的优化支持向量机(SVM)技术,它是一种机器学习模型。此外,采用蜂群算法对支持向量机算法的参数进行了优化。结果:在第一阶段,使用Mask R-CNN架构,当截距过并集(IOU)值取0.5时,平均精度(mAP)值为0.754。同时,当应用5倍交叉验证时,mAP值为0.736。通过对Mask R-CNN和SVM算法的超参数优化,两级分类过程的准确率为96.36%。此外,最终的假阴性率和假阳性率分别为6.20%和2.57%。结论:与类似的研究和当今远程医疗技术的解释相比,使用所提出的模型,在二维(2D)图像上以低成本和高精度更成功地检测出血和向医生呈现可疑区域。
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引用次数: 0
Placebo-controlled randomized double-blind comparison of the analgesic efficacy of lidocaine spray and etofenamate spray in pain control of rib fractures. 安慰剂对照随机双盲比较利多卡因喷雾剂和依托芬酯喷雾剂在肋骨骨折疼痛控制中的镇痛效果。
IF 1.1 4区 医学 Q4 EMERGENCY MEDICINE Pub Date : 2023-08-01 DOI: 10.14744/tjtes.2023.40652
Safa Dönmez, Ahmet Burak Erdem, Alp Şener, Furkan Altas, Reyhan İrem Mutlu

Background: As far as we could detect, we could not find any study in literature on the analgesic efficacy of spray forms of lidocaine and etofenamate in rib fractures. In this study, our aim is to empirically compare the analgesic efficacy of etofenamate spray, lidocaine 10% spray and placebo spray in the management of pain secondary to trauma secondary to isolated rib fractures.

Methods: The study was designed according to a single-center, prospective, randomized, placebo-controlled double-blind study model. About 30 sealed envelopes were prepared for each of the 3 groups and 30 patients were included in each group. A total of 84 cases were included in the study (three groups: 27, 28, 29).

Results: Numeric rating scale (NRS) grades at admission and at 15-30-60-120 min were similar between the three groups (P>0.05). Analysis findings of NRS perception differences between the initial NRS level and the 15-30-60-120th min NRS difference at the 0-120th min showed more lidocaine spray organs, and it was not clearly perceived that these four parameters went between the 3 groups for the outline.

Conclusion: The analgesic efficacy of lidocaine 10% spray, etofenamate spray, and placebo spray used together with standard dexketoprofen 50 mg intravenous treatment in the pain management of rib fractures were similar to each other and although there was a difference at the 120th min, this difference was not statistically significant.

背景:就我们所能检测到的而言,我们在文献中找不到任何关于利多卡因和依托芬酯喷雾剂对肋骨骨折的镇痛效果的研究。在本研究中,我们的目的是根据经验比较埃托非那酯喷雾剂、10%利多卡因喷雾剂和安慰剂喷雾剂在治疗孤立性肋骨骨折继发创伤疼痛方面的镇痛效果。方法:本研究采用单中心、前瞻性、随机、安慰剂对照双盲研究模型。为3组中的每一组准备了大约30个密封信封,每组包括30名患者。本研究共纳入84例病例(三组:27、28、29),并且没有清楚地察觉到这四个参数在轮廓的三组之间。结论:10%利多卡因喷雾剂、依托非那末喷雾剂和安慰剂喷雾剂与标准右酮洛芬50mg静脉注射治疗肋骨骨折的镇痛效果相似,尽管在第120分钟有差异,但差异无统计学意义。
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引用次数: 0
Is prophylactic anti-convulsive treatment necessary in subdural hematomas? 硬膜下血肿是否需要预防性抗惊厥治疗?
IF 1.1 4区 医学 Q4 EMERGENCY MEDICINE Pub Date : 2023-08-01 DOI: 10.14744/tjtes.2023.06554
Mehmet Ozan Durmaz, Adem Dogan, Mehmet Can Ezgü, Ali Kaplan

Background: Subdural hematoma (SDH) is usually an emergent clinical condition in neurosurgery. The relationship between the SDH and epilepsy is not well established. Therefore, the use of anti-convulsive treatment in patients with SDH is controversial. The aim of this study is to analyze the presence of seizures in patients who underwent surgery for SDH.

Methods: Patients who were operated on for SDH in our department between 2016 and 2021 were reviewed retrospectively. Demographic features, Glasgow Coma Scale (GCS) score at admission, type of SDH, location, etiology, type of surgical intervention, presence of seizures, and re-operation were evaluated.

Results: There were 175 patients with SDH. There is a statistically significant difference between the frequency of seizures and the type of SDH. More seizures were observed in acute SDH than in the others. There is also a statistically significant difference between the GCS score and the frequency of seizures. Patients with a GCS score <12 at admission had more frequent seizures than patients with a score of 12 or higher. No statistically significant difference was found between factors such as etiology, re-operation, hematoma location, and the development of seizures.

Conclusion: Anti-convulsive treatment may be recommended in patients with acute SDH and a low GCS score at admission. Further studies with larger series should be performed to determine the most appropriate anti-convulsive agent for patients with SDH.

背景:硬膜下血肿(SDH)通常是神经外科的一种紧急临床情况。SDH与癫痫之间的关系尚不明确。因此,在SDH患者中使用抗惊厥治疗是有争议的。本研究的目的是分析接受SDH手术的患者是否存在癫痫发作。方法:回顾性分析2016年至2021年间在我科接受SDH手术治疗的患者。评估人口统计学特征、入院时格拉斯哥昏迷量表(GCS)评分、SDH类型、位置、病因、手术干预类型、癫痫发作情况和再次手术。结果:SDH患者175例。癫痫发作的频率和SDH的类型之间存在统计学上的显著差异。急性SDH患者的癫痫发作次数多于其他患者。GCS评分和癫痫发作频率之间也存在统计学上的显著差异。GCS评分的患者结论:对于入院时GCS评分较低的急性SDH患者,建议进行抗惊厥治疗。应进行更大系列的进一步研究,以确定最适合SDH患者的抗惊厥药物。
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引用次数: 0
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Ulusal Travma Ve Acil Cerrahi Dergisi-Turkish Journal of Trauma & Emergency Surgery
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